CN108478847B - Oily gauze for treating wound and preparation method thereof - Google Patents

Oily gauze for treating wound and preparation method thereof Download PDF

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CN108478847B
CN108478847B CN201810189089.9A CN201810189089A CN108478847B CN 108478847 B CN108478847 B CN 108478847B CN 201810189089 A CN201810189089 A CN 201810189089A CN 108478847 B CN108478847 B CN 108478847B
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mixture coating
mixture
wounds
oil
coating
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CN108478847A (en
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崔景民
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Shanghai Junlian Medical Equipment Co ltd
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Abstract

The invention discloses a oily sand cloth for treating wounds and a preparation method thereof, and particularly discloses an oily sand cloth for treating wounds, bedsores and postoperative inflammatory wounds and a preparation method thereof, the oily sand cloth for treating wounds, bedsores and postoperative inflammatory wounds comprises a cloth body and a mixture coating coated on the cloth body, wherein the mixture coating comprises: olive oil, sunflower oil, beeswax, vaseline, bismuth subgallate and borneol. The oily gauze for treating wounds, bedsores and postoperative inflammatory wounds adopts an aseptic coating process, is cut, packaged and sterilized, is convenient for doctors to use, is easy to take off after use, has controllable coating area, does not cause sensitive skin, and can promote the growth of wound surfaces.

Description

Oily gauze for treating wound and preparation method thereof
Technical Field
The invention belongs to the technical field of medical supplies, and relates to a piece of oily gauze, in particular to a piece of oily gauze for treating wounds, bedsores and postoperative inflammatory wounds; meanwhile, the invention also relates to a preparation method of the oily gauze for treating wounds, bedsores and postoperative inflammatory wounds.
Background
With the increasing patients with bedsore, wound infection disunion, burn and contusion of epidermis, a dressing-changed oily sand cloth is clinically needed for auxiliary treatment, after the period of wound exudate is finished, the oily sand cloth with proper specification is selected according to the size of the wound to cover the wound, the wound is covered and bound with a piece of sterile gauze, the wound is isolated from the external environment after use, wound infection is not suitable, the wound is not bonded, and the wound tissue growth is facilitated.
The existing oil gauze is coated by Vaseline, the wound growth is not easily promoted by clinical observation, and the clinical significance is not great.
In view of the above, there is an urgent need to design a new oil gauze to overcome the above-mentioned disadvantages of the existing vaseline coating.
Disclosure of Invention
The invention aims to provide a oily gauze for treating wounds, bedsores and postoperative inflammatory wounds and a preparation method thereof.
The invention provides a tarpaulin in a first aspect, which comprises a cloth body and a mixture coating coated on the cloth body, wherein the mixture coating comprises: olive oil, sunflower oil, beeswax, vaseline, and borneol.
In another preferred embodiment, the mixture coating further comprises bismuth subgallate.
In another preferred embodiment, the mixture coating comprises:
Figure BDA0001591164350000011
in another preferred embodiment, the mixture coating comprises:
Figure BDA0001591164350000012
Figure BDA0001591164350000021
in another preferred embodiment, the mixture coating comprises:
Figure BDA0001591164350000022
in another preferred embodiment, the mixture coating comprises:
Figure BDA0001591164350000023
in another preferred embodiment, the mixture coating comprises:
Figure BDA0001591164350000024
in another preferred embodiment, the periphery of the oil sand cloth is provided with an adhesive cloth
In another preferred example, the oil sand cloth is distributed with air-permeable through holes.
In another preferred example, the line distance of the oil sand cloth is as follows: 1.5 to 2.0mm x 1.5 to 2.0 mm.
In a second aspect of the present invention, there is provided a method of preparing the tarpaulin of the first aspect of the present invention, the method comprising the steps of:
(1) preparing raw material mixture
Mixing oleum Olivarum, oleum Helianthi, Cera flava, vaseline, Borneolum Syntheticum, and bismuth subgallate, and emulsifying to obtain emulsion;
(2) coating the emulsion obtained in the step (1) on a flat cloth body;
(3) and cutting the coated cloth body to obtain the oil gauze.
In a third aspect of the present invention, there is provided a compound coating for use in the treatment of wounds, bedsores, post-operative inflamed wounds, said compound coating comprising: olive oil, sunflower oil, beeswax, vaseline, and borneol.
In another preferred embodiment, the mixture coating further comprises bismuth subgallate.
In another preferred embodiment, the mixture coating comprises:
Figure BDA0001591164350000031
in another preferred embodiment, the mixture coating comprises:
Figure BDA0001591164350000032
in another preferred embodiment, the mixture coating comprises:
Figure BDA0001591164350000033
in another preferred embodiment, the mixture coating comprises:
Figure BDA0001591164350000034
in another preferred embodiment, the mixture coating comprises:
Figure BDA0001591164350000035
Figure BDA0001591164350000041
it is to be understood that within the scope of the present invention, the above-described features of the present invention and those specifically described below (e.g., in the examples) may be combined with each other to form new or preferred embodiments. Not to be reiterated herein, but to the extent of space.
Drawings
FIG. 1 is a flow chart of the present invention.
Detailed Description
The technical problem to be solved by the invention is as follows: provides the oily gauze for treating wounds, bedsores and postoperative inflammatory wounds, which is easy to take off after use, has controllable coating area, does not cause skin allergy, promotes the growth of wound surface tissue cells and is easy to separate out exudates.
In addition, the invention also provides a preparation method of the oily gauze for treating wounds, bedsores and postoperative inflammatory wounds, and the prepared oily gauze is easy to take off after use, controllable in coating area, free from skin allergy, capable of promoting the growth of wound tissue cells and easy to separate out exudates.
In order to solve the technical problems, the invention adopts the following technical scheme:
an oil gauze for treating wounds, bedsores and post-operative inflammatory wounds, comprising: a cloth body and a mixture coating coated on the cloth body; the periphery of the oiled sandcloth is provided with a sticky adhesive tape;
the mixture coating comprises olive oil, sunflower oil, beeswax, vaseline, borneol and bismuth subgallate; the concrete mass percentages are:
30% of olive oil; 25.8% of sunflower oil; 12% of beeswax; 32% of vaseline; 0.1% of borneol: 0.1% of bismuth subgallate: the content of condensate is more than 99.5 percent.
A tarpaulin for treating a wound, the tarpaulin for treating a wound comprising: a cloth body and a mixture coating coated on the cloth body;
the mixture coating comprises olive oil, sunflower oil, beeswax, vaseline, borneol and bismuth subgallate; as a preferred scheme of the invention, the mixture coating comprises the following specific mass percentages:
1-49% of olive oil; 1-49% of sunflower oil; 1-20% of beeswax; 2-60% of vaseline; 0.01-10% of borneol: 0.1-5% of bismuth subgallate; the content of condensate is more than 99.5 percent.
In a preferred embodiment of the present invention, the periphery of the oil gauze is provided with a sticky tape.
A method of preparing a tarpaulin for the treatment of wounds, said method comprising the steps of:
step S1, preparing a raw material mixture, taking a set amount of olive oil, sunflower oil, beeswax, vaseline, borneol and Tibetan plant extract, and placing the substances into equipment for vacuum mixing and emulsification to be uniform;
the concrete mass percentages are: 25% of olive oil; 25% of sunflower oil; 8% of beeswax; 40% of vaseline; 0.1% of borneol: 1.9% of Tibetan plant extract; the content of condensate is more than 99.5 percent;
step S2, coating the mixed emulsion on a flat cloth body;
step S3, cutting the coated oil gauze;
and step S4, arranging adhesive tapes on the periphery of the cut oil gauze.
Step S5, packaging the prepared oil gauze; and step S1-S5 are fully automatically completed.
A method of preparing a tarpaulin for the treatment of wounds, said method comprising the steps of:
step S1, preparing a raw material mixture, taking a set amount of olive oil, sunflower oil, beeswax, vaseline, borneol and Tibetan plant extract, and uniformly stirring;
step S2, coating the mixed emulsion on a cloth body;
and step S3, cutting and packaging the coated oil gauze.
As a preferred scheme of the invention, the mixture coating comprises the following specific mass percentages:
1-49% of olive oil; 1-49% of sunflower oil; 1-20% of beeswax; 2-60% of vaseline; 0.01-10% of borneol: 0.1-5% of Tibetan plant extract; the content of condensate is more than 99.5 percent.
As a preferred embodiment of the present invention, steps S1, S2, and S3 are fully automated.
A tarpaulin for treating a wound, the tarpaulin for treating a wound comprising: gauze, paste mixture and preparation process.
The process flow comprises the following steps: special production environment, raw material weighing, mixing, vacuum emulsification, coating, leveling, cutting, compound packaging, special mode sterilization and external packaging.
The natural raw materials are mixed, coated and cut into the oily gauze with different specifications, the mixture of olive oil, sunflower oil, beeswax, vaseline, borneol, bismuth subgallate and the like is adopted, the aseptic coating process, the leveling, the cutting, the compound packaging and the sterilization are adopted, the use by doctors is convenient, the oily gauze is easy to take off after being used, the coating area is controllable, the skin is not allergic, the exudate is easy to separate out, and the growth of wound tissue cells is promoted.
The above materials are put into a professional device according to the proportion, mixed and emulsified evenly in vacuum, coated in a full-automatic sterile manner, leveled, cut, packaged in a compound manner, and sterilized for use. When in use, the oily gauze is stuck on the wound, the periphery is stuck, and the wound is wrapped by sterile gauze.
The invention has the beneficial effects that: the oily gauze for treating the wound, provided by the invention, adopts the mixture of olive oil, sunflower oil, beeswax, vaseline, borneol, bismuth subgallate and the like, adopts an aseptic coating process, is cut, packaged and sterilized, is convenient for a doctor to use, is easy to take off after use, has controllable coating area, does not cause skin allergy, is easy to separate out exudates, promotes the growth of wound tissue cells and the like.
The present invention will be described in further detail with reference to the following examples. It should be understood that these examples are for illustrative purposes only and are not intended to limit the scope of the present invention. Experimental procedures without specifying the detailed conditions in the following examples are generally carried out according to the conditions recommended by the manufacturers. Unless otherwise indicated, percentages and parts are by weight. The test materials and reagents used in the following examples are commercially available without specific reference.
Example 1
The oil sand cloth for treating wounds, bedsores and postoperative inflammation wounds provided by the embodiment comprises: a cloth body and a mixture coating coated on the cloth body; the periphery of the oiled sandcloth is provided with a sticky adhesive tape;
the mixture coating comprises olive oil, sunflower oil, beeswax, vaseline, borneol and bismuth subgallate; the concrete mass percentages are:
25% of olive oil; 25% of sunflower oil; 8% of beeswax; 40% of vaseline; 0.1% of borneol: 1.9% of bismuth subgallate; the solid content is more than 99.5 percent.
Referring to fig. 1, the present invention discloses a method for preparing a tarpaulin for treating wounds, bedsores and post-operative inflamed wounds, which comprises the following steps:
step S1, preparing a raw material mixture, taking a set amount of olive oil, sunflower oil, beeswax, vaseline, borneol and bismuth subgallate, and placing the above substances into a device for vacuum mixing and emulsification;
in the embodiment, the specific mass percentages are as follows: 25% of olive oil; 25% of sunflower oil; 8% of beeswax; 40% of vaseline; 0.1% of borneol: 1.9% of bismuth subgallate; the content of condensate is more than 99.5 percent;
(S2) coating the mixed emulsion on a flat cloth body;
(S3) cutting the coated oil gauze;
step S4, adhesive tapes are arranged on the periphery of the cut oil gauze.
Step S5, packaging the prepared oil gauze; and step S1-S5 are fully automatically completed.
Example 2
The oil sand cloth for treating wounds provided by the embodiment comprises: a cloth body and a mixture coating coated on the cloth body; the mixture coating comprises olive oil, sunflower oil, beeswax, vaseline, borneol and bismuth subgallate.
In this embodiment, the mixture coating comprises: 20kg of olive oil, 30kg of sunflower oil, 5kg of beeswax, 50kg of vaseline, 0.01kg of borneol and 0.02kg of bismuth subgallate.
The preparation method of the tarpaulin for treating wounds provided by the embodiment comprises the following steps:
step S1, preparing a raw material mixture, taking a set amount of olive oil, sunflower oil, beeswax, vaseline, borneol and bismuth subgallate, and uniformly stirring;
step S2, coating the mixed emulsion on a cloth body;
and step S3, cutting and packaging the coated oil gauze.
Steps S1, S2, S3 may be fully automated.
Example 3
The oil sand cloth for treating wounds provided by the embodiment comprises: a cloth body and a mixture coating coated on the cloth body; the mixture coating comprises olive oil, sunflower oil, beeswax, vaseline, borneol and bismuth subgallate.
In this embodiment, the mixture coating comprises: 30kg of olive oil, 29kg of sunflower oil, 10kg of beeswax, 30kg of vaseline, 0.02kg of borneol and 0.02kg of bismuth subgallate.
The preparation method of the tarpaulin for treating wounds provided by the embodiment comprises the following steps:
step S1, preparing a raw material mixture, taking a set amount of olive oil, sunflower oil, beeswax, vaseline, borneol and bismuth subgallate, and uniformly stirring;
step S2, coating the mixed emulsion on a cloth body;
and step S3, cutting and packaging the coated oil gauze.
Steps S1, S2, S3 may be fully automated.
Example 4
The oil sand cloth for treating wounds provided by the embodiment comprises: a cloth body and a mixture coating coated on the cloth body; the mixture coating comprises olive oil, sunflower oil, beeswax, vaseline, borneol and bismuth subgallate.
In this embodiment, the mixture coating comprises: 30kg of olive oil, 20kg of sunflower oil, 10kg of beeswax, 35kg of vaseline, 0.01kg of bismuth subgallate and 0.02kg of borneol.
The preparation method of the tarpaulin for treating wounds provided by the embodiment comprises the following steps:
step S1, preparing a raw material mixture, taking a set amount of olive oil, sunflower oil, beeswax, vaseline, borneol and bismuth subgallate, and uniformly stirring;
step S2, coating the mixed emulsion on a cloth body;
and step S3, cutting and packaging the coated oil gauze.
Steps S1, S2, S3 may be fully automated.
Example 5
The oil sand cloth for treating wounds provided by the embodiment comprises: a cloth body and a mixture coating coated on the cloth body; the mixture coating comprises olive oil, sunflower oil, beeswax, vaseline, borneol and bismuth subgallate.
In this embodiment, the mixture coating comprises: 30kg of olive oil, 10kg of sunflower oil, 5kg of beeswax, 50kg of vaseline, 0.05kg of bismuth subgallate and 0.01kg of borneol.
The preparation method of the tarpaulin for treating wounds provided by the embodiment comprises the following steps:
step S1, preparing a raw material mixture, taking a set amount of olive oil, sunflower oil, beeswax, vaseline, borneol and bismuth subgallate, and uniformly stirring;
step S2, coating the mixed emulsion on a cloth body;
and step S3, cutting and packaging the coated oil gauze.
Steps S1, S2, S3 may be fully automated.
Comparative example:
Figure BDA0001591164350000081
example 6 animal model test
New Zealand female white rabbits (2 kg-3kg in weight) were shaved and sterilized on the ventral side of the rabbit without the great vessels, and then the whole skin was microscopically excised with a trephine to the cartilage surface. Circular wound incisions of about 0.6cm in diameter were obtained, 5 on each side.
The oil gauze in the embodiments 1-5 and the respective proportions are cut into proper sizes, attached to the surface of the wound, changed every 1 day, and the wound surface is observed to count the time for healing of the wound. The test results are shown in the following table.
TABLE 1
Group of Mean days of healing Group of Mean days of healing
Example 1 6.5 days Comparative example 1 13.5 days
Example 2 6.0 days Comparative example 2 11.0 days
Example 3 5.5 days Comparative example 3 10.5 days
Example 4 6.5 days Comparative example 4 Can not heal within 20 days
Example 5 7.0 days
From the experimental results, the oil gauze can obviously shorten the wound healing time. In animal model experiments, the inventor finds that the wounds of the experimental animals of the comparative experimental group are not only long in healing time, but also inflammatory infection is observed, and more than about half of the experimental animals have abnormal wound inflammation. The experimental animals of the groups using the examples of the present invention showed no infection nor sensitization.
In conclusion, the oily gauze for treating the wound provided by the invention adopts the mixture of olive oil, sunflower oil, beeswax, vaseline, borneol, bismuth subgallate and the like, adopts an aseptic coating process, is cut, packaged and sterilized, is convenient for doctors to use, and has the advantages of easiness in taking off after use, controllable coating area, no sensitivity to skin, promotion of wound growth and the like.
All documents referred to herein are incorporated by reference into this application as if each were individually incorporated by reference. Furthermore, it should be understood that various changes and modifications of the present invention can be made by those skilled in the art after reading the above teachings of the present invention, and these equivalents also fall within the scope of the present invention as defined by the appended claims.

Claims (9)

1. The oily gauze is characterized by comprising a gauze body and a mixture coating coated on the gauze body, wherein the mixture coating consists of olive oil, sunflower oil, beeswax, vaseline, borneol and bismuth subgallate, and the mixture coating consists of the following components in percentage by weight:
Figure FDA0002779731500000011
2. the tarpaulin of claim 1, wherein the mixture coating is formed by:
Figure FDA0002779731500000012
3. the tarpaulin of claim 2, wherein the mixture coating is formed by:
Figure FDA0002779731500000013
4. a tarpaulin according to claim 3, wherein said coating of a mixture is formed by:
Figure FDA0002779731500000014
5. the tarpaulin of claim 1, wherein said tarpaulin has a tape at its periphery.
6. A method for preparing a tarpaulin for the treatment of wounds, bedsores and post-operative inflamed wounds according to claim 1, characterized in that it comprises the steps of:
(1) preparing raw material mixture
Mixing oleum Olivarum, oleum Helianthi, Cera flava, vaseline, Borneolum Syntheticum, and bismuth subgallate, and emulsifying to obtain emulsion;
(2) coating the emulsion obtained in the step (1) on a flat cloth body;
(3) and cutting the coated cloth body to obtain the oil gauze.
7. A mixture coating for treating wounds, bedsores and postoperative inflammatory wounds, which is characterized in that the mixture coating is composed of olive oil, sunflower oil, beeswax, vaseline, borneol and bismuth subgallate; wherein:
Figure FDA0002779731500000023
8. the mixture coating of claim 7, wherein the mixture coating is formed from:
Figure FDA0002779731500000021
9. the mixture coating of claim 7, wherein the mixture coating is formed from:
Figure FDA0002779731500000022
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