CN108478721A - A kind of astringing to arrest bleeding frost and preparation method thereof - Google Patents
A kind of astringing to arrest bleeding frost and preparation method thereof Download PDFInfo
- Publication number
- CN108478721A CN108478721A CN201810537682.8A CN201810537682A CN108478721A CN 108478721 A CN108478721 A CN 108478721A CN 201810537682 A CN201810537682 A CN 201810537682A CN 108478721 A CN108478721 A CN 108478721A
- Authority
- CN
- China
- Prior art keywords
- parts
- frost
- astringing
- arrest bleeding
- powder
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
- A61K33/10—Carbonates; Bicarbonates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/36—Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/82—Theaceae (Tea family), e.g. camellia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/889—Arecaceae, Palmae or Palmaceae (Palm family), e.g. date or coconut palm or palmetto
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/898—Orchidaceae (Orchid family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Medical Informatics (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Botany (AREA)
- Alternative & Traditional Medicine (AREA)
- Dermatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Cell Biology (AREA)
- Inorganic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Developmental Biology & Embryology (AREA)
- Immunology (AREA)
- Virology (AREA)
- Zoology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
Abstract
The invention belongs to technical field of pharmaceuticals, and in particular to the raw material group of a kind of astringing to arrest bleeding frost and preparation method thereof, the hemostasis frost becomes：Micarex, marmor serpentinatum, montmorillonite, cogongrass rhizome extractive, bletilla, crinis trachycarpi, Plant Soot, carbonized hair, oxhide gelatin, black tea-seed oil, deionized water.By adding a variety of natural minerals stones, Chinese herbal medicine and other functional ingredient; raw material natural environmental-protective; it has no toxic side effect, can stop blooding rapidly, energy part is molten disconnected and absorbs sore face exudate; there is convergence protection wound; promote the growth and healing of sore face granulation tissue, has hemostasis fast, incrustation is fast; the effects that not infecting, not being afraid of water logging sweat stain.
Description
Technical field
The present invention relates to a kind of technical field of pharmaceuticals, more particularly, to a kind of astringing to arrest bleeding frost and preparation method thereof.
Background technology
Inside and outside bleeding blood caused by a variety of causes is extremely common in daily life, traumatic hemorrhage can be divided into external hemorrhage and
Two kinds of internal haemorrhage.Blood flows to body epigenesist from wound and is known as external hemorrhage, is common in knife hurts, stabs, bullet wound and spreading are hindered etc..
If skin does not have wound, blood to be flowed in tissue, internal organs or body cavity by the blood vessel ruptured, referred to as internal haemorrhage.Cause internal haemorrhage
Reason is complexity far beyond external hemorrhage, and processing is also more difficult, needs hospital therapy more.Blood is stopped, is the traumatic external hemorrhage for the treatment of
Main purpose.Different according to external hemorrhage type, Hemostasis is also different.It is compressing and hemostasis with packs clinically to do multi-purpose
Method, or hemostasis, the uses of drug in clinic but current these stop blooding are achieved the purpose that by the method for intravenous injection
Method is single, inconvenient to use, and anthemorrhagic speed is slower, and haemostatic effect is undesirable, and price is generally relatively high.
Chinese patent《A kind of hemostatic medicine composition and its application》(number of patent application：CN201710337887.7) open
A kind of hemostatic medicine composition, the hemostatic medicine composition are prepared by nano silicon dioxide, montmorillonite, honeysuckle,
To various traumatic hemorrhage can quick-acting haemostatic powder, anti-inflammatory analgetic promotes the healing of wound to have notable curative effect.But its drug is to the later stage
Resume treatment slow, scar of dispelling effect unobvious.
Invention content
To solve the above-mentioned problems, the present invention provides a kind of astringing to arrest bleeding frosts and preparation method thereof, a variety of by adding
Natural minerals stone, Chinese herbal medicine and other functional ingredient, raw material natural environmental-protective have no toxic side effect, and can stop blooding rapidly, there is convergence protection wound
Effect, have hemostasis fast, incrustation is fast, the effects that not infecting, be not afraid of water logging sweat stain.
The present invention can be achieved through the following technical solutions：
A kind of astringing to arrest bleeding frost, is made of the raw material of following parts by weight：30~40 parts of micarex, marmor serpentinatum 15~25
Part, 3~7 parts of montmorillonite, 6~12 parts of cogongrass rhizome extractive, 4~10 parts of bletilla, 1~3 part of crinis trachycarpi, 1~2 part of Plant Soot, blood
1~3 part of remaining charcoal, 1~3 part of oxhide gelatin, 5~9 parts of black tea-seed oil, 10~15 parts of deionized water.
Preferably, a kind of astringing to arrest bleeding frost, is made of the raw material of following parts by weight：32~38 parts of micarex, marmor serpentinatum
18~22 parts, 4~6 parts of montmorillonite, 8~10 parts of cogongrass rhizome extractive, 6~8 parts of bletilla, 1.6~2.4 parts of crinis trachycarpi, Plant Soot
1.2~1.8 parts, 1.3~2.7 parts of carbonized hair, 1.3~2.7 parts of oxhide gelatin, 6~8 parts of black tea-seed oil, 12~14 parts of deionized water.
Preferably, a kind of astringing to arrest bleeding frost, is made of the raw material of following parts by weight：35 parts of micarex, 20 parts of marmor serpentinatum,
5 parts of montmorillonite, 9 parts of cogongrass rhizome extractive, 7 parts of bletilla, 2 parts of crinis trachycarpi, 1.5 parts of Plant Soot, 2 parts of carbonized hair, 2 parts of oxhide gelatin,
7 parts of black tea-seed oil, 13 parts of deionized water.
Preferably, the preparation method of the cogongrass rhizome extractive is：Rhizoma imperatae is cleaned into drying, is crushed, 10 mesh sieve is crossed, it will
The water that 3~5 times of amounts are added in rhizoma imperatae coarse powder decocts 3~4 times, decocts 2~3h every time, merges water cooking liquid, and filtering takes filtrate in 30
It is concentrated under reduced pressure at~60 DEG C, is freeze-dried, obtains cogongrass rhizome extractive.
Preferably, a kind of preparation method of astringing to arrest bleeding frost, includes the following steps：
(1) by blocky micarex and marmor serpentinatum impurity elimination, various sizes of particle, particle are ground by medicinal herb grinder
Diameter is in 1 μm~1mm；Mineral powder after crushing is heat-treated by different temperature, in 300 DEG C, 500 DEG C, 700 DEG C, 900 DEG C of temperature
Degree is lower to handle 5~6h, and the mineral powder of heat treatment is uniformly mixed with montmorillonite, obtains mixture；
(2) it by bletilla, crinis trachycarpi, Plant Soot and carbonized hair grind into powder and is uniformly mixed, powder crosses 100~120 mesh
Sieve, obtains traditional Chinese medicine powder；
(3) mixture, traditional Chinese medicine powder, cogongrass rhizome extractive and deionized water are mixed evenly, obtain water phase；
(4) water phase is added in emulsification pot, 80 DEG C of heat preservations in emulsifying pot are added oxhide gelatin and black tea-seed oil, start
Stirring, 3~5min of homogeneous, stirring cooling obtain the astringing to arrest bleeding frost of the invention prepared.
Each main composition mechanism of action of the present invention is as follows：
Micarex, return lung, liver, the spleen channel.Kidney tonifying, astringing to arrest bleeding.Deficient for internal lesion caused by overexertion, dizziness is palpitated with fear, epilepsy, and sympotoms caused by cold factors are long
Malaria, sore, carbuncle and painful swelling, knife wound bleeding.Convergence astringent method can make blood stagnation to reach haemostatic effect.Marmor serpentinatum is metamorphic rock class rock
Stone has the work(of removing blood stasis and hemostasis containing the serpentine griotte that more or less, for noise made in coughing or vomiting blood, hemostasis, traumatic hemorrhage, the pain of injury caused by falling and tumbling.
Rhizoma imperatae is the dry rhizome of grass cogongrass, has hemostasis, anti-inflammatory, diuresis, rhizoma imperatae is sweet in flavor, property
Cold, return lung, stomach, bladder warp have the effect of cooling blood and hemostasis, reducing fever and causing diuresis.It can be used for treating pyreticosis polydipsia, haematemesis, hematuria, heat
Drench the diseases such as puckery pain, difficult urination, oedema and jaundice.
Bletilla has the effect of astringing to arrest bleeding, detumescence and promoting granulation；Crinis trachycarpi is mild-natured, bitter, has effects that controlling of bleeding with astringents；Hundred
Careless frost has effects that hemostasis, heat-clearing dispersing blood stasis；Carbonized hair has effects that hemostasia and dissipation blood stasis, myogenic sore.
The present invention has following advantageous effect：
Astringing to arrest bleeding frost prepared by the present invention is by adding a variety of natural minerals stones, Chinese herbal medicine and other functional ingredient, raw material day
So environmental protection, has no toxic side effect, can stop blooding rapidly, and energy part is molten disconnected and absorbs sore face exudate, there is convergence protection wound,
Promote the growth and healing of sore face granulation tissue, has hemostasis fast, incrustation is fast, the effects that not infecting, be not afraid of water logging sweat stain.
Specific implementation mode
In order to make the technical means, the creative features, the aims and the efficiencies achieved by the present invention be easy to understand, tie below
Specific embodiment is closed, the present invention is further explained.
Embodiment 1
A kind of astringing to arrest bleeding frost, is made of the raw material of following parts by weight：30 parts of micarex, 15 parts of marmor serpentinatum, montmorillonite 3
Part, 6 parts of cogongrass rhizome extractive, 4 parts of bletilla, 1 part of crinis trachycarpi, 1 part of Plant Soot, 1 part of carbonized hair, 1 part of oxhide gelatin, black tea-seed oil 5
Part, 10 parts of deionized water.
The preparation method of the cogongrass rhizome extractive is：Rhizoma imperatae is cleaned into drying, is crushed, 10 mesh sieve is crossed, by rhizoma imperatae
The water that 3~5 times of amounts are added in coarse powder decocts 3~4 times, decocts 2~3h every time, merges water cooking liquid, and filtering takes filtrate in 30~60 DEG C
Under be concentrated under reduced pressure, be freeze-dried, obtain cogongrass rhizome extractive.
A kind of preparation method of astringing to arrest bleeding frost, includes the following steps：
(1) by blocky micarex and marmor serpentinatum impurity elimination, various sizes of particle, particle are ground by medicinal herb grinder
Diameter is at 1 μm；Mineral powder after crushing is heat-treated by different temperature, at a temperature of 300 DEG C, 500 DEG C, 700 DEG C, 900 DEG C
5h is handled, the mineral powder of heat treatment is uniformly mixed with montmorillonite, obtains mixture；
(2) it by bletilla, crinis trachycarpi, Plant Soot and carbonized hair grind into powder and is uniformly mixed, powder sieves with 100 mesh sieve, and obtains
Traditional Chinese medicine powder；
(3) mixture, traditional Chinese medicine powder, cogongrass rhizome extractive and deionized water are mixed evenly, obtain water phase；
(4) water phase is added in emulsification pot, 80 DEG C of heat preservations in emulsifying pot are added oxhide gelatin and black tea-seed oil, start
Stirring, homogeneous 3min, stirring cooling obtain the astringing to arrest bleeding frost of the invention prepared.
Embodiment 2
A kind of astringing to arrest bleeding frost, is made of the raw material of following parts by weight：32 parts of micarex, 18 parts of marmor serpentinatum, montmorillonite 4
It is part, 8 parts of cogongrass rhizome extractive, 6 parts of bletilla, 1.6 parts of crinis trachycarpi, 1.2 parts of Plant Soot, 1.3 parts of carbonized hair, 1.3 parts of oxhide gelatin, black
6 parts of tea-seed oil, 12 parts of deionized water.
A kind of preparation method of astringing to arrest bleeding frost, includes the following steps：
(1) by blocky micarex and marmor serpentinatum impurity elimination, various sizes of particle, particle are ground by medicinal herb grinder
Diameter is at 100 μm；Mineral powder after crushing is heat-treated by different temperature, in 300 DEG C, 500 DEG C, 700 DEG C, 900 DEG C of temperature
Lower processing 5.2h, the mineral powder of heat treatment is uniformly mixed with montmorillonite, obtains mixture；
(2) it by bletilla, crinis trachycarpi, Plant Soot and carbonized hair grind into powder and is uniformly mixed, powder crosses 105 mesh sieve, obtains
Traditional Chinese medicine powder；
(3) mixture, traditional Chinese medicine powder, cogongrass rhizome extractive and deionized water are mixed evenly, obtain water phase；
(4) water phase is added in emulsification pot, 80 DEG C of heat preservations in emulsifying pot are added oxhide gelatin and black tea-seed oil, start
Stirring, homogeneous 3min, stirring cooling obtain the astringing to arrest bleeding frost of the invention prepared.
Embodiment 3
A kind of astringing to arrest bleeding frost, is made of the raw material of following parts by weight：35 parts of micarex, 20 parts of marmor serpentinatum, montmorillonite 5
Part, 9 parts of cogongrass rhizome extractive, 7 parts of bletilla, 2 parts of crinis trachycarpi, 1.5 parts of Plant Soot, 2 parts of carbonized hair, 2 parts of oxhide gelatin, black tea-seed oil
7 parts, 13 parts of deionized water.
A kind of preparation method of astringing to arrest bleeding frost, includes the following steps：
(1) by blocky micarex and marmor serpentinatum impurity elimination, various sizes of particle, particle are ground by medicinal herb grinder
Diameter is at 300 μm；Mineral powder after crushing is heat-treated by different temperature, in 300 DEG C, 500 DEG C, 700 DEG C, 900 DEG C of temperature
Lower processing 5.5h, the mineral powder of heat treatment is uniformly mixed with montmorillonite, obtains mixture；
(2) it by bletilla, crinis trachycarpi, Plant Soot and carbonized hair grind into powder and is uniformly mixed, powder crosses 110 mesh sieve, obtains
Traditional Chinese medicine powder；
(3) mixture, traditional Chinese medicine powder, cogongrass rhizome extractive and deionized water are mixed evenly, obtain water phase；
(4) water phase is added in emulsification pot, 80 DEG C of heat preservations in emulsifying pot are added oxhide gelatin and black tea-seed oil, start
Stirring, homogeneous 4min, stirring cooling obtain the astringing to arrest bleeding frost of the invention prepared.
Embodiment 4
A kind of astringing to arrest bleeding frost, is made of the raw material of following parts by weight：38 parts of micarex, 22 parts of marmor serpentinatum, montmorillonite 6
Part, 10 parts of cogongrass rhizome extractive, 8 parts of bletilla, 2.4 parts of crinis trachycarpi, 1.8 parts of Plant Soot, 2.7 parts of carbonized hair, 2.7 parts of oxhide gelatin,
8 parts of black tea-seed oil, 14 parts of deionized water.
A kind of preparation method of astringing to arrest bleeding frost, includes the following steps：
(1) by blocky micarex and marmor serpentinatum impurity elimination, various sizes of particle, particle are ground by medicinal herb grinder
Diameter is at 600 μm；Mineral powder after crushing is heat-treated by different temperature, in 300 DEG C, 500 DEG C, 700 DEG C, 900 DEG C of temperature
Lower processing 5.8h, the mineral powder of heat treatment is uniformly mixed with montmorillonite, obtains mixture；
(2) it by bletilla, crinis trachycarpi, Plant Soot and carbonized hair grind into powder and is uniformly mixed, powder crosses 115 mesh sieve, obtains
Traditional Chinese medicine powder；
(3) mixture, traditional Chinese medicine powder, cogongrass rhizome extractive and deionized water are mixed evenly, obtain water phase；
(4) water phase is added in emulsification pot, 80 DEG C of heat preservations in emulsifying pot are added oxhide gelatin and black tea-seed oil, start
Stirring, homogeneous 5min, stirring cooling obtain the astringing to arrest bleeding frost of the invention prepared.
Embodiment 5
A kind of astringing to arrest bleeding frost, is made of the raw material of following parts by weight：40 parts of micarex, 25 parts of marmor serpentinatum, montmorillonite 7
Part, 12 parts of cogongrass rhizome extractive, 10 parts of bletilla, 3 parts of crinis trachycarpi, 2 parts of Plant Soot, 3 parts of carbonized hair, 3 parts of oxhide gelatin, black tea-seed oil
9 parts, 15 parts of deionized water.
A kind of preparation method of astringing to arrest bleeding frost, includes the following steps：
(1) by blocky micarex and marmor serpentinatum impurity elimination, various sizes of particle, particle are ground by medicinal herb grinder
Diameter is in 1mm；Mineral powder after crushing is heat-treated by different temperature, at a temperature of 300 DEG C, 500 DEG C, 700 DEG C, 900 DEG C
6h is handled, the mineral powder of heat treatment is uniformly mixed with montmorillonite, obtains mixture；
(2) it by bletilla, crinis trachycarpi, Plant Soot and carbonized hair grind into powder and is uniformly mixed, powder crosses 120 mesh sieve, obtains
Traditional Chinese medicine powder；
(3) mixture, traditional Chinese medicine powder, cogongrass rhizome extractive and deionized water are mixed evenly, obtain water phase；
(4) water phase is added in emulsification pot, 80 DEG C of heat preservations in emulsifying pot are added oxhide gelatin and black tea-seed oil, start
Stirring, homogeneous 5min, stirring cooling obtain the astringing to arrest bleeding frost of the invention prepared.
Comparative example 1
Difference lies in do not add micarex in the hemostasis frost of preparation with embodiment 1.
Comparative example 2
Difference lies in without addition cogongrass rhizome extractive in the hemostasis frost of preparation with embodiment 1.
Efficacy validation
70 rabbit of selection are tested, weight 3-4kg, are randomly divided into 7 groups, every group 10, every rabbit are cut off
Arteria auricularis, the hemostasis frost for using after free bleeding 5s, 5s 1-5 of the embodiment of the present invention and comparative example 1-2 to prepare respectively, takes 3-5g to apply
It is overlying at bleeding, experimental result is as shown in table 1 below：
Haemostatic effect of each hemostasis frost of table 1 to rabbit
| Group | Average bleeding stopping period/s of rabbit arteria auricularis |
| Embodiment 1 | 79±7 |
| Embodiment 2 | 80±5 |
| Embodiment 3 | 74±4 |
| Embodiment 4 | 77±9 |
| Embodiment 5 | 81±5 |
| Comparative example 1 | 125±7 |
| Comparative example 2 | 117±9 |
As seen from the above table, by the comparison of embodiment 1 and comparative example 1 it is found that add micarex in the hemostasis frost of preparation,
The average bleeding stopping period of rabbit can be shortened 36.8%；By the comparison of embodiment 1 and comparative example 2 it is found that preparation hemostasis
Cogongrass rhizome extractive is added in frost, the average bleeding stopping period of rabbit can be shortened 32.5%.
In summary, the hemostasis frost prepared using the embodiment of the present invention, anthemorrhagic speed are significantly better than comparative example group, explanation
Addition micarex and cogongrass rhizome extractive in astringing to arrest bleeding frost prepared by the present invention can effectively improve the use effect of hemostasis frost
Fruit.
Several embodiments of the invention above described embodiment only expresses, the description thereof is more specific and detailed, but simultaneously
Cannot the limitation to the scope of the claims of the present invention therefore be interpreted as.It should be pointed out that for those of ordinary skill in the art
For, without departing from the inventive concept of the premise, various modifications and improvements can be made, these belong to the guarantor of the present invention
Protect range.
Claims (5)
1. a kind of astringing to arrest bleeding frost, which is characterized in that be made of the raw material of following parts by weight：30~40 parts of micarex, pistil
15~25 parts of stone, 3~7 parts of montmorillonite, 6~12 parts of cogongrass rhizome extractive, 4~10 parts of bletilla, 1~3 part of crinis trachycarpi, Plant Soot 1
~2 parts, 1~3 part of carbonized hair, 1~3 part of oxhide gelatin, 5~9 parts of black tea-seed oil, 10~15 parts of deionized water.
2. a kind of astringing to arrest bleeding frost according to claim 1, which is characterized in that be made of the raw material of following parts by weight：
32~38 parts of micarex, 18~22 parts of marmor serpentinatum, 4~6 parts of montmorillonite, 8~10 parts of cogongrass rhizome extractive, 6~8 parts of bletilla, palm fibre
1.6~2.4 parts of palmitic acid charcoal, 1.2~1.8 parts of Plant Soot, 1.3~2.7 parts of carbonized hair, 1.3~2.7 parts of oxhide gelatin, black tea-seed oil 6~
8 parts, 12~14 parts of deionized water.
3. a kind of astringing to arrest bleeding frost according to claim 2, which is characterized in that be made of the raw material of following parts by weight：
35 parts of micarex, 20 parts of marmor serpentinatum, 5 parts of montmorillonite, 9 parts of cogongrass rhizome extractive, 7 parts of bletilla, 2 parts of crinis trachycarpi, Plant Soot 1.5
Part, 2 parts of carbonized hair, 2 parts of oxhide gelatin, 7 parts of black tea-seed oil, 13 parts of deionized water.
4. according to a kind of astringing to arrest bleeding frost of claims 1 to 3 any one of them, which is characterized in that the cogongrass rhizome extractive
Preparation method be：Rhizoma imperatae is cleaned into drying, is crushed, 10 mesh sieve is crossed, the water that rhizoma imperatae coarse powder is added to 3~5 times of amounts decocts 3
~4 times, 2~3h is decocted every time, merges water cooking liquid, filtering takes filtrate to be concentrated under reduced pressure at 30~60 DEG C, is freeze-dried,
Obtain cogongrass rhizome extractive.
5. a kind of prepare such as a kind of method of astringing to arrest bleeding frost of Claims 1 to 4 any one of them, which is characterized in that including
Following steps：
(1) by blocky micarex and marmor serpentinatum impurity elimination, various sizes of particle is ground by medicinal herb grinder, grain diameter exists
1 μm~1mm；Mineral powder after crushing is heat-treated by different temperature, at a temperature of 300 DEG C, 500 DEG C, 700 DEG C, 900 DEG C
5~6h is handled, the mineral powder of heat treatment is uniformly mixed with montmorillonite, obtains mixture；
(2) it by bletilla, crinis trachycarpi, Plant Soot and carbonized hair grind into powder and is uniformly mixed, powder crosses 100~120 mesh sieve, obtains
Traditional Chinese medicine powder；
(3) mixture, traditional Chinese medicine powder, cogongrass rhizome extractive and deionized water are mixed evenly, obtain water phase；
(4) water phase is added in emulsification pot, 80 DEG C of heat preservations in emulsify pot, addition oxhide gelatin and black tea-seed oil, start stirring,
3~5min of homogeneous, stirring cooling obtain the astringing to arrest bleeding frost of the invention prepared.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810537682.8A CN108478721A (en) | 2018-05-29 | 2018-05-29 | A kind of astringing to arrest bleeding frost and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810537682.8A CN108478721A (en) | 2018-05-29 | 2018-05-29 | A kind of astringing to arrest bleeding frost and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN108478721A true CN108478721A (en) | 2018-09-04 |
Family
ID=63352596
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810537682.8A Withdrawn CN108478721A (en) | 2018-05-29 | 2018-05-29 | A kind of astringing to arrest bleeding frost and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN108478721A (en) |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1097622A (en) * | 1994-06-06 | 1995-01-25 | 郭文峰 | Styptic powder |
| WO2005032571A2 (en) * | 2003-10-06 | 2005-04-14 | Peter Kolata | Method for the production of a medicinal tincture from higher mushrooms, medicinal tincture and use thereof |
| EP1608381B1 (en) * | 2002-02-15 | 2007-11-21 | Marie-José Touche | Therapeutic and consmetic application for a composition containing lycopene |
| CN107007754A (en) * | 2017-04-07 | 2017-08-04 | 贵州盛茂白芨开发有限公司 | A kind of bletilla dissipate and preparation method thereof |
-
2018
- 2018-05-29 CN CN201810537682.8A patent/CN108478721A/en not_active Withdrawn
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1097622A (en) * | 1994-06-06 | 1995-01-25 | 郭文峰 | Styptic powder |
| EP1608381B1 (en) * | 2002-02-15 | 2007-11-21 | Marie-José Touche | Therapeutic and consmetic application for a composition containing lycopene |
| WO2005032571A2 (en) * | 2003-10-06 | 2005-04-14 | Peter Kolata | Method for the production of a medicinal tincture from higher mushrooms, medicinal tincture and use thereof |
| CN107007754A (en) * | 2017-04-07 | 2017-08-04 | 贵州盛茂白芨开发有限公司 | A kind of bletilla dissipate and preparation method thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN106581439A (en) | Traditional Chinese medicine composition for treating wounds, diabetic feet and skin ulceration, and preparation method thereof | |
| CN104225258A (en) | Traditional Chinese medicine composition for promoting wound healing | |
| CN104840749A (en) | Externally used heavy-metal-free ointment for treating skin wound and preparation method | |
| CN112891514A (en) | Novel external hemostatic powder | |
| CN108478721A (en) | A kind of astringing to arrest bleeding frost and preparation method thereof | |
| CN102247533B (en) | External drug for treating trauma and preparation method thereof | |
| CN103816247A (en) | External Chinese medicinal composition capable of preventing scarring healing of external injury and preparation method for external Chinese medicinal composition | |
| CN105561382A (en) | Dendrobium officinale liquid woundplast and preparation method thereof | |
| CN101757389A (en) | External traditional Chinese medicine for treating heloma | |
| CN104721444A (en) | Chinese medicinal compositions for treating burns and preparation methods thereof | |
| CN112190660A (en) | Traditional Chinese medicine composition for promoting wound healing and preparation method thereof | |
| CN110090261A (en) | A kind for the treatment of method for treating burn and scald and other wounds | |
| CN104127474A (en) | Formula and preparation method of traditional Chinese medicine for treating burns and scalds | |
| CN103977266A (en) | Dendrobium officinale traditional Chinese medicine composition for hemostasis | |
| CN113384561B (en) | Allergy-free dysmenorrhea patch and preparation method thereof | |
| CN107693714A (en) | A kind of Chinese medicine composition for repairing face skin care and its preparation method and application | |
| CN103181964B (en) | Traditional Chinese medicine composition for treating animal body surface injuries and preparation method thereof | |
| CN114848778B (en) | Compound hoop ointment for diminishing inflammation, relieving pain and promoting wound healing as well as preparation method and application thereof | |
| CN105832644A (en) | Erodium stephanianum-containing acne-treatment traditional Chinese medicine composition for cosmetics | |
| CN105521326A (en) | Traditional Chinese medicine for treating hebra prurigo | |
| CN117860845A (en) | Prescription of trauma specific medicine and preparation method thereof | |
| CN106038898A (en) | Hemostatic drug for field emergency treatment | |
| CN104161908A (en) | Chinese herbal bone-setting ointment and preparation method thereof | |
| CN104739728A (en) | Quick pox-removing liquor and preparation method thereof | |
| CN103690728A (en) | External medicament for treating scalds and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WW01 | Invention patent application withdrawn after publication |
Application publication date: 20180904 |
|
| WW01 | Invention patent application withdrawn after publication |