CN108474028A - 鉴别并区分遗传样品的系统及方法 - Google Patents

鉴别并区分遗传样品的系统及方法 Download PDF

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Publication number
CN108474028A
CN108474028A CN201680079030.3A CN201680079030A CN108474028A CN 108474028 A CN108474028 A CN 108474028A CN 201680079030 A CN201680079030 A CN 201680079030A CN 108474028 A CN108474028 A CN 108474028A
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CN
China
Prior art keywords
probes
nucleic acid
biochip
analyte
probe
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Pending
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CN201680079030.3A
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English (en)
Chinese (zh)
Inventor
罗伯特·查尔斯·卡因
理查德·沈
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Revere Biosensors Inc
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Revere Biosensors Inc
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Priority to CN202210950570.1A priority Critical patent/CN115287335A/zh
Publication of CN108474028A publication Critical patent/CN108474028A/zh
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
    • C12Q2525/10—Modifications characterised by
    • C12Q2525/117—Modifications characterised by incorporating modified base
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
    • C12Q2525/10—Modifications characterised by
    • C12Q2525/161—Modifications characterised by incorporating target specific and non-target specific sites
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
    • C12Q2525/10—Modifications characterised by
    • C12Q2525/185—Modifications characterised by incorporating bases where the precise position of the bases in the nucleic acid string is important
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2527/00—Reactions demanding special reaction conditions
    • C12Q2527/107—Temperature of melting, i.e. Tm
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2537/00—Reactions characterised by the reaction format or use of a specific feature
    • C12Q2537/10—Reactions characterised by the reaction format or use of a specific feature the purpose or use of
    • C12Q2537/143—Multiplexing, i.e. use of multiple primers or probes in a single reaction, usually for simultaneously analyse of multiple analysis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2563/00—Nucleic acid detection characterized by the use of physical, structural and functional properties
    • C12Q2563/107—Nucleic acid detection characterized by the use of physical, structural and functional properties fluorescence
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A90/00—Technologies having an indirect contribution to adaptation to climate change
    • Y02A90/10—Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
CN201680079030.3A 2015-11-16 2016-11-15 鉴别并区分遗传样品的系统及方法 Pending CN108474028A (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202210950570.1A CN115287335A (zh) 2015-11-16 2016-11-15 鉴别并区分遗传样品的系统及方法

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201562256049P 2015-11-16 2015-11-16
US62/256,049 2015-11-16
US201662306597P 2016-03-10 2016-03-10
US62/306,597 2016-03-10
PCT/US2016/062090 WO2017087416A1 (en) 2015-11-16 2016-11-15 Systems and methods for identifying and distinguishing genetic samples

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CN202210950570.1A Division CN115287335A (zh) 2015-11-16 2016-11-15 鉴别并区分遗传样品的系统及方法

Publications (1)

Publication Number Publication Date
CN108474028A true CN108474028A (zh) 2018-08-31

Family

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Family Applications (2)

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CN201680079030.3A Pending CN108474028A (zh) 2015-11-16 2016-11-15 鉴别并区分遗传样品的系统及方法
CN202210950570.1A Pending CN115287335A (zh) 2015-11-16 2016-11-15 鉴别并区分遗传样品的系统及方法

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Country Status (8)

Country Link
US (2) US11725233B2 (https=)
EP (1) EP3377654B1 (https=)
JP (2) JP7315326B2 (https=)
CN (2) CN108474028A (https=)
AU (2) AU2016357723A1 (https=)
CA (1) CA3005430A1 (https=)
DK (1) DK3377654T3 (https=)
WO (1) WO2017087416A1 (https=)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109735598A (zh) * 2019-02-13 2019-05-10 中国人民解放军总医院 琥珀酸弧菌属在鉴别和/或区分不同种族个体中的应用
CN110869512A (zh) * 2017-05-09 2020-03-06 雷瑞生物传感器有限责任公司 鉴别并区分遗传样品的系统及方法
US12565676B2 (en) 2019-03-01 2026-03-03 Revere Biosensors, Llc Systems and methods for separating decoded arrays

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3377654B1 (en) 2015-11-16 2024-01-31 Revere Biosensors, LLC Systems and methods for identifying and distinguishing genetic samples
CN108588284B (zh) * 2018-05-10 2022-06-10 山东师范大学 基于酶催化可控自组装生物条码检测htlv-ii dna的方法

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US5593867A (en) * 1994-04-18 1997-01-14 Becton, Dickinson And Company Fluorerscence polarization detection of nucleic acid amplication
WO2002042775A2 (en) * 2000-11-27 2002-05-30 Genevention L.L.C. Clinically intelligent diagnostic devices and methods
US20040202577A1 (en) * 1994-08-08 2004-10-14 Mcneil John Austin Automated system and method for simultaneously performing a plurality of signal-based assays
US20050032095A1 (en) * 2003-05-23 2005-02-10 Wigler Michael H. Virtual representations of nucleotide sequences
US20080057513A1 (en) * 2006-09-01 2008-03-06 Ventana Medical Systems, Inc. Method for producing nucleic acid probes
US20090181378A1 (en) * 2007-04-27 2009-07-16 Sanders Heather R Nucleic acid detection combining amplification with fragmentation
US20120122737A1 (en) * 2008-03-10 2012-05-17 Illumina, Inc. Methods for selecting and amplifying polynucleotides
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US5563034A (en) * 1989-04-17 1996-10-08 Brink; Donald E. Negative control probes that are identical in sequence but opposite in polarity to the target, or are complementary in sequence and of the same polarity as the target, for use in nucleic acid hybridization assays
US5593867A (en) * 1994-04-18 1997-01-14 Becton, Dickinson And Company Fluorerscence polarization detection of nucleic acid amplication
US20040202577A1 (en) * 1994-08-08 2004-10-14 Mcneil John Austin Automated system and method for simultaneously performing a plurality of signal-based assays
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US20050032095A1 (en) * 2003-05-23 2005-02-10 Wigler Michael H. Virtual representations of nucleotide sequences
US20080057513A1 (en) * 2006-09-01 2008-03-06 Ventana Medical Systems, Inc. Method for producing nucleic acid probes
US20090181378A1 (en) * 2007-04-27 2009-07-16 Sanders Heather R Nucleic acid detection combining amplification with fragmentation
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WO2014185803A2 (en) * 2013-05-15 2014-11-20 Stab Vida - Investigação E Serviços Em Ciências Biológicas Lda Biochip, antigen bouquet, optical reader and method for detecting and monitoring diseases

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110869512A (zh) * 2017-05-09 2020-03-06 雷瑞生物传感器有限责任公司 鉴别并区分遗传样品的系统及方法
CN109735598A (zh) * 2019-02-13 2019-05-10 中国人民解放军总医院 琥珀酸弧菌属在鉴别和/或区分不同种族个体中的应用
US12565676B2 (en) 2019-03-01 2026-03-03 Revere Biosensors, Llc Systems and methods for separating decoded arrays

Also Published As

Publication number Publication date
JP2022023083A (ja) 2022-02-07
US11725233B2 (en) 2023-08-15
WO2017087416A1 (en) 2017-05-26
AU2016357723A1 (en) 2018-06-14
EP3377654B1 (en) 2024-01-31
DK3377654T3 (da) 2024-02-19
CA3005430A1 (en) 2017-05-26
CN115287335A (zh) 2022-11-04
EP3377654A1 (en) 2018-09-26
JP2018533965A (ja) 2018-11-22
US20240218431A1 (en) 2024-07-04
AU2022275409B2 (en) 2025-10-02
AU2022275409A1 (en) 2023-01-05
AU2022275409C1 (en) 2026-01-15
JP7315326B2 (ja) 2023-07-26
EP3377654A4 (en) 2019-07-10
US20200087717A1 (en) 2020-03-19
JP7434243B2 (ja) 2024-02-20

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Application publication date: 20180831