CN108465056A - A kind of Chinese medicine composition and preparation method thereof for treating amyotrophia - Google Patents
A kind of Chinese medicine composition and preparation method thereof for treating amyotrophia Download PDFInfo
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Abstract
This application discloses a kind of Chinese medicine compositions for treating amyotrophia in field of Chinese herbal medicine technology, including following raw material：Uncaria, the fleece-flower root, flax benevolence, the stem of noble dendrobium, the shell of seaear, radix polygonati officinalis, radix rehmanniae recen, Radix Paeoniae Alba, the tuber of dwarf lilyturf and Radix Glycyrrhizae, the raw material are in parts by weight：5~10 parts of uncaria, 5~10 parts of the fleece-flower root, 5~10 parts of flax benevolence, 15~30 parts of the stem of noble dendrobium, 15~30 parts of the shell of seaear, 15~30 parts of radix polygonati officinalis, 6~12 parts of radix rehmanniae recen, 6~12 parts of Radix Paeoniae Alba, 6~12 parts of the tuber of dwarf lilyturf, 2~5 parts of Radix Glycyrrhizae.The Chinese medicine composition of the present invention focuses on all medicines share and promotes the production of body fluid fluid infusion, and strengthening the spleen and replenishing qi, myogenic plays impotence, more preferably to the therapeutic effect of amyotrophia.
Description
Technical field
The invention belongs to field of Chinese herbal medicine technology more particularly to a kind of Chinese medicine composition for treating amyotrophia and its preparation sides
A kind of method, and in particular to Chinese medicine composition and preparation method thereof for treating myasthenia and thenar amyotrophia.
Background technology
Muscular dystrophy refers to band muscular dystrophy, meat fiber attenuates even disappear etc. caused by muscle volume contract
It is small, it is the genetic disease of one group of damage human muscle.Muscular dystrophy shows as progressive skeletal muscle atrophy, muscle protein
Matter lacks and the death of muscle cell or tissue.The cause of disease mainly has neurogenic muscular atrophy, muscle-derived amyotrophia, useless property flesh
Atrophy and other reasons amyotrophia.Muscle nutrition situation more has with nervous system in addition to the pathological change of musculature itself
Substantial connection.Spinal cord disease often results in muscular dystrophy and muscular atrophy occurs.Amyotrophia patient due to muscular atrophy, flesh without
Power and long-term bed, easy Complicating Pneumonia In Patients, bedsore etc., in addition Most patients there is bulbar paralysis symptom, give patient vitals to constitute
Greatly threaten.
Currently, many scholars in countries in the world explore the disease, but it is still unclear so far.Since the course of disease of this disease is slow
Slowly, certain types are up to normal life span.This brings very big difficulty to the treatment of this disease and curative effect.Many since this century
Person is to find the treatment of this disease to have done a large amount of effort, though there is hundreds of clinical drug application, still affirms curative effect without having so far
Drug.
Invention content
The invention is intended to provide a kind of Chinese medicine composition for treating amyotrophia, to solve the prior art in treatment amyotrophia
The defect of curative effect drug is not affirmed.
The technical scheme is that a kind of Chinese medicine composition for treating amyotrophia, including following raw material：Uncaria, He Shou
Crow, flax benevolence, the stem of noble dendrobium, the shell of seaear, radix polygonati officinalis, radix rehmanniae recen, Radix Paeoniae Alba, the tuber of dwarf lilyturf and Radix Glycyrrhizae, the raw material are in parts by weight：
5~10 parts of uncaria, 5~10 parts of the fleece-flower root, 5~10 parts of flax benevolence, 15~30 parts of the stem of noble dendrobium, 15~30 parts of the shell of seaear, radix polygonati officinalis 15~
30 parts, 6~12 parts of radix rehmanniae recen, 6~12 parts of Radix Paeoniae Alba, 6~12 parts of the tuber of dwarf lilyturf, 2~5 parts of Radix Glycyrrhizae.
Preferably, the raw material is in parts by weight：5 parts of uncaria, 5 parts of the fleece-flower root, 5 parts of flax benevolence, 15 parts of the stem of noble dendrobium,
15 parts of the shell of seaear, 15 parts of radix polygonati officinalis, 6 parts of radix rehmanniae recen, 6 parts of Radix Paeoniae Alba, 6 parts of the tuber of dwarf lilyturf, 2 parts of Radix Glycyrrhizae.
It is further preferred that the raw material is in parts by weight：8 parts of uncaria, 8 parts of the fleece-flower root, 8 parts of flax benevolence, stone
22 parts of dry measure used in former times, 22 parts of the shell of seaear, 22 parts of radix polygonati officinalis, 20 parts of radix rehmanniae recen, 10 parts of Radix Paeoniae Alba, 10 parts of the tuber of dwarf lilyturf, 3 parts of Radix Glycyrrhizae.
Another step is preferred, and the raw material is in parts by weight：10 parts of uncaria, 10 parts of the fleece-flower root, 10 parts of flax benevolence,
30 parts of the stem of noble dendrobium, 30 parts of the shell of seaear, 30 parts of radix polygonati officinalis, 12 parts of radix rehmanniae recen, 12 parts of Radix Paeoniae Alba, 12 parts of the tuber of dwarf lilyturf, 5 parts of Radix Glycyrrhizae.
The operation principle of the present invention：The Chinese medicine composition of the present invention is formed using 10 taste Chinese traditional medicine compositions, wherein uncaria：Heat-clearing
Soothing the liver relieves dizziness, high fever, infantile convulsions, epilepsy, etc. and relieves the pain, and has decompression, calm, anticonvulsion, and platelet aggregation and anti-thrombosis function, clinic is inhibited to be mainly used for
Control total numbness, half of wind, neural paralysis, hypertension etc..Fleece-flower root pharmacological property is bitter, sweet, puckery, tepor, Return liver, the heart, kidney channel.Have
The effect of nourishing the blood and yin relaxes bowel, wind-dispelling, removing toxic substances can treat Light-headedness, and palpitaition is had a sleepless night, soreness and weakness of waist and knees, poliosis,
Tinnitus, seminal emission, dry constipation of intestines, chronic malaria body void, rubella itch, sore carbuncle, scrofula, hemorrhoid etc..Flax benevolence：Nature and flavor sweet and neutral, returns spleen,
Stomach, large intestine channel have effects that relax bowel.Blood deficiency and depleted fluid, dry constipation of intestines etc. can be treated.The stem of noble dendrobium：It is sweet in flavor, flat, nontoxic, wound
In, gas under eliminating impediment, mend in never sufficient, flat stomach gas, long muscle has the function of tonifying five zang organs, thick stomach, by force the moon strengthening the essence.The shell of seaear：
It is calming the liver, it clears liver and improve vision.Radix polygonati officinalis：Nourishing Yin and moistening lung, nourishing the stomach of promoting the production of body fluid.Radix rehmanniae recen：Clearing heat and cooling blood, nourishing Yin and promoting production of body fluid, ease constipation.Radix Paeoniae Alba：
Nature and flavor, picric acid are slightly cold, and Return liver spleen two passes through, and function cures mainly, and cloudy, soothing the liver, relieving spasm to stop pain, deficiency of Yin blood, blood deficiency and sthenic liver-energy, dizziness are held back in blood-nourishing
Mesh is spent, insomnia, costalgia of chest, spasm of limbs, incoordination between the liver and the spleen, liver-qi depression, incessant sweating due to debility.Radix Glycyrrhizae pharmacological property sweet and neutral, returns spleen, stomach,
The effect of heart, lung channel, have and middle emergency, moistening lung are detoxified, coordinating the drug actions of a prescription.It can treat weakness of the spleen and the stomach, burnout deficiency of food, abdominal pain is just
It is half congealed, four limbs contraction, palpitaition, hysteria, consumptive lung disease cough；It is raw with controlling abscess of throat, ulcerative carbuncle pyogenic infections, infant fetal toxin and drug, food
Object poisoning etc..
Amyotrophia is native endowment deficiency, and essence loses blood and is unable to nutrition muscle muscles and bones less, gradually appears muscle inability, atrophy.
Meanwhile The spleen and stomach provide the material basis of the acquired, metaplasia qi and blood, the nutrition vital organs of the human body, muscle muscles and bones, and spleen governing muscles, weakness of the spleen and the stomach, qi and blood life
Change deficiency, muscle, which is difficult nutrition, causes muscular dystrophy, muscular atrophy, myasthenia, main pathogenesis to be the loss of internal organ vital essence, muscles and bones
Muscle lose support and caused by, it is to treat big method that general treatment when took, which is filling liver kidney, strengthening the bones and muscles, degrading the channel,.And this hair
Bright Chinese medicine composition is with radix polygonati officinalis, radix rehmanniae recen and flax benevolence altogether for monarch drug in a prescription；Uncaria, the fleece-flower root are ministerial drug altogether；Radix Paeoniae Alba, the tuber of dwarf lilyturf,
Stem of noble dendrobium benefiting qi and nourishing yin, it is adjutant to make yin-yang match, treating YANG within YIN；The shell of seaear, Radix Glycyrrhizae dissipate to make medicine, coordinating the drug actions of a prescription with pungent-warm row.
By first " promoting the production of body fluid " fluid infusion of radix polygonati officinalis, radix rehmanniae recen and flax benevolence, body fluid is in addition to metaplasia blood, sperm, gastric juice and marrow liquid, and in energy
Internal organs are grown, becomes the liquid of internal organs, especially gastric juice, first nourishes gastric juice, uncaria, fleece-flower root auxiliary monarch drug in a prescription is recycled to promote the production of body fluid later,
Radix Paeoniae Alba, the tuber of dwarf lilyturf, the stem of noble dendrobium, the shell of seaear and Radix Glycyrrhizae yin-yang match, with coordinating the drug actions of a prescription, strengthening the spleen and replenishing qi is nourishing liver and kidney, and myogenic plays impotence,
It strengthens muscles and bones, it is slow for tendon and vessel using fluid infusion of promoting the production of body fluid, it is weak and feeble, it is with the passing of time unable to voluntary activity hand or walks about and cause
Muscular atrophy has fabulous therapeutic effect, more preferably especially for thenar amyotrophia therapeutic effect.
Beneficial effects of the present invention：The Chinese medicine composition of the present invention focuses on all medicines share and promotes the production of body fluid fluid infusion, strengthening the spleen and replenishing qi,
Myogenic plays impotence, more preferably to the therapeutic effect of amyotrophia.
A kind of preparation method of Chinese medicine composition that treating amyotrophia, includes the following steps：Step 1: stock：In proportion
Prepare the uncaria, the fleece-flower root, flax benevolence, the stem of noble dendrobium, the shell of seaear, radix polygonati officinalis, radix rehmanniae recen, Radix Paeoniae Alba, the tuber of dwarf lilyturf and the Radix Glycyrrhizae that cook；
Step 2: mixing chopping：3cm fragments below are cut into after above-mentioned raw materials are mixed, by the loading of above-mentioned fragment
In gauze, Chinese medicine package is obtained；
Step 3: cooking：Chinese medicine package is boiled in water 15~20min, obtains a liquid, Chinese medicine package pull out add water it is pan-fried
20~25min obtains secondary liquid, and Chinese medicine package adds water pan-fried 10~15min after pulling out, obtains liquid three times, removes Chinese medicine package,
Three liquid tune of boiling medicine are converted uniformly up to composition.
By decocting three times, decoction liquor shares three times, makes the drug effect in decoction liquor 90% or more, reduces pharmacological property in medicine
Residual in slag ensures its curative effect.
Further, the uncaria is 3 years or more wild uncarias.3 years or more wild uncaria drug effects are best.
Further, the raw material further includes having umbellate pore furgus.Umbellate pore furgus, property slightly sweet flavor is flat, and light to ooze profit, relatively clearing damp and promoting diuresis, matches
Radix Glycyrrhizae is closed to use, heat-clearing promotes blood circulation, and avoids because QI-blood circulation is different and neurotrophasthenia, caused by passages through which vital energy circulates muscle speed vertical not receive
Into withering.
Further, high pressure boiling machine, the pressure in the high pressure boiling machine are used when the step 2 cooks
For 0.4~0.8MPa.It is boiled medicine by high pressure boiling machine, using the principle of pressurization, it is enough to decoct out drug effect in a short time
Chinese medicine composition.
Specific implementation mode
It describes in detail to the technical method of the present invention with reference to specific embodiment：
A kind of embodiment 1, preparation method of Chinese medicine composition that treating amyotrophia, includes the following steps：
Step 1: stock：In proportion prepare cook 10 parts of uncaria, 10 parts of the fleece-flower root, 10 parts of flax benevolence, 30 parts of the stem of noble dendrobium,
30 parts of the shell of seaear, 30 parts of radix polygonati officinalis, 12 parts of radix rehmanniae recen, 12 parts of Radix Paeoniae Alba, 12 parts of the tuber of dwarf lilyturf, 5 parts of Radix Glycyrrhizae；
Step 2: mixing chopping：3cm fragments below are cut into after above-mentioned raw materials are mixed, by the loading of above-mentioned fragment
In gauze, Chinese medicine package is obtained；
Step 3: cooking：Chinese medicine package plus water are put into high pressure decocting machine, be fried boiling 15~20min at 0.8MPa, obtains
Liquid, Chinese medicine package is pulled out under 0.4MPa again plus water is in pan-fried 20~25min, obtains secondary liquid, Chinese medicine package adds again after pulling out
Water decocts 10~15min under 0.8MPa again, obtains liquid three times, removes Chinese medicine package, and three liquid tune of boiling medicine are converted uniformly up to composition.
Embodiment 2 differs only in 5 parts of uncaria, 5 parts of the fleece-flower root, 5 parts of flax benevolence, 15 parts of the stem of noble dendrobium, Shi Jue with embodiment 1
Bright 15 parts, 15 parts of radix polygonati officinalis, 6 parts of radix rehmanniae recen, 6 parts of Radix Paeoniae Alba, 6 parts of the tuber of dwarf lilyturf, 2 parts of Radix Glycyrrhizae.
Embodiment 3 differs only in 8 parts of uncaria, 8 parts of the fleece-flower root, 8 parts of flax benevolence, 22 parts of the stem of noble dendrobium, Shi Jue with embodiment 1
Bright 22 parts, 22 parts of radix polygonati officinalis, 20 parts of radix rehmanniae recen, 10 parts of Radix Paeoniae Alba, 10 parts of the tuber of dwarf lilyturf, 3 parts of Radix Glycyrrhizae.
The Radix Glycyrrhizae for increasing by 2~5 parts when differing only in step 1 stock of embodiment 4 and embodiment 1.
Above-mentioned uncaria was using 3 years or more wild uncarias.
1 part of above-mentioned raw materials are 1g.
Experimental verification：100 muscular atrophy patients are randomly selected, are randomly divided into 5 groups, by the Chinese medicine of above-described embodiment 1~4
The decoction of composition is taken to 4 groups of patients therein, daily 1 dose, and control group is using conventional treatment (low frequency or medium frequency electric thorn
Swash, Neurotrophic drugs, coordinate acupuncture/acusector and massage).
After 3 months, stopping a day, the electromyogram and muscle girth meaurement of comparison check patient obtain its curative effect.
Wherein, MUAP is moving cell action potential in muscle fibre.
By measuring time limit, the wave amplitude of motor unit potential, whether there is or not spontaneous electrical activity and muscle are big in the case of peace and quiet
The wave mode and wave amplitude that power is shunk, while judging according to muscle degree of enclosing ratio the therapeutic effect of amyotrophia.It to sum up analyzes, the present invention
Examples 1 to 4 compare control group for, therapeutic effect is more preferable, wherein especially best with the therapeutic effect of embodiment 4.
It will be apparent to those skilled in the art that without departing from the structure of the invention, several deformations can also be made
And improvement, these should also be considered as protection scope of the present invention, these all do not interfere with the effect and patent that the present invention is implemented.
Claims (8)
1. a kind of Chinese medicine composition for treating amyotrophia, which is characterized in that including following raw material：Uncaria, the fleece-flower root, flax benevolence,
The stem of noble dendrobium, the shell of seaear, radix polygonati officinalis, radix rehmanniae recen, Radix Paeoniae Alba, the tuber of dwarf lilyturf and Radix Glycyrrhizae, the raw material are in parts by weight：Uncaria 5~10
Part, 5~10 parts of the fleece-flower root, 5~10 parts of flax benevolence, 15~30 parts of the stem of noble dendrobium, 15~30 parts of the shell of seaear, 15~30 parts of radix polygonati officinalis, Radix Rehmanniae
6~12 parts yellow, 6~12 parts of Radix Paeoniae Alba, 6~12 parts of the tuber of dwarf lilyturf, 2~5 parts of Radix Glycyrrhizae.
2. the Chinese medicine composition for the treatment of amyotrophia according to claim 1, which is characterized in that the raw material is according to parts by weight
Number is calculated as：5 parts of uncaria, 5 parts of the fleece-flower root, 5 parts of flax benevolence, 15 parts of the stem of noble dendrobium are 15 parts of the shell of seaear, 15 parts of radix polygonati officinalis, 6 parts of radix rehmanniae recen, white
6 parts of Chinese herbaceous peony, 6 parts of the tuber of dwarf lilyturf, 2 parts of Radix Glycyrrhizae.
3. the Chinese medicine composition for the treatment of amyotrophia according to claim 1, which is characterized in that the raw material is according to parts by weight
Number is calculated as：It is 8 parts of uncaria, 8 parts of the fleece-flower root, 8 parts of flax benevolence, 22 parts of the stem of noble dendrobium, 22 parts of the shell of seaear, 22 parts of radix polygonati officinalis, 20 parts of radix rehmanniae recen, white
10 parts of Chinese herbaceous peony, 10 parts of the tuber of dwarf lilyturf, 3 parts of Radix Glycyrrhizae.
4. the Chinese medicine composition for the treatment of amyotrophia according to claim 1, which is characterized in that the raw material is according to parts by weight
Number is calculated as：10 parts of uncaria, 10 parts of the fleece-flower root, 10 parts of flax benevolence, 30 parts of the stem of noble dendrobium, 30 parts of the shell of seaear, 30 parts of radix polygonati officinalis, radix rehmanniae recen 12
Part, 12 parts of Radix Paeoniae Alba, 12 parts of the tuber of dwarf lilyturf, 5 parts of Radix Glycyrrhizae.
5. the preparation method of the Chinese medicine composition for the treatment of amyotrophia according to any one of claims 1 to 4, which is characterized in that
Include the following steps：Step 1: stock：Prepare the uncaria cooked, the fleece-flower root, flax benevolence, the stem of noble dendrobium, the shell of seaear, jade in proportion
Bamboo, radix rehmanniae recen, Radix Paeoniae Alba, the tuber of dwarf lilyturf and Radix Glycyrrhizae；
Step 2: mixing chopping：3cm fragments below are cut into after above-mentioned raw materials are mixed, by the loading gauze of above-mentioned fragment
In, obtain Chinese medicine package；
Step 3: cooking：Chinese medicine package is boiled in water 15~20min, obtains a liquid, Chinese medicine package pulls out and adds water pan-fried 20~
25min obtains secondary liquid, and Chinese medicine package adds water pan-fried 10~15min after pulling out, obtains liquid three times, removes Chinese medicine package, and three decoct
Liquid tune is converted uniformly up to composition.
6. the Chinese medicine composition for the treatment of amyotrophia according to claim 5, which is characterized in that the uncaria is 3 years or more
Wild uncaria.
7. the Chinese medicine composition for the treatment of amyotrophia according to claim 6, which is characterized in that the raw material further includes having pig
Siberian cocklebur.
8. the Chinese medicine composition for the treatment of amyotrophia according to claim 7, which is characterized in that the step 2 cook when
Time uses high pressure boiling machine, and the pressure in the high pressure boiling machine is 0.4~0.8MPa.
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| CN106190718A (en) * | 2016-07-05 | 2016-12-07 | 袁新 | A kind of ground winter fleece-flower root wine |
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