CN108452255A - Plaster and preparation method thereof for treating chest impediment and cardialgia - Google Patents
Plaster and preparation method thereof for treating chest impediment and cardialgia Download PDFInfo
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- CN108452255A CN108452255A CN201810379021.7A CN201810379021A CN108452255A CN 108452255 A CN108452255 A CN 108452255A CN 201810379021 A CN201810379021 A CN 201810379021A CN 108452255 A CN108452255 A CN 108452255A
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- parts
- plaster
- cardialgia
- chest impediment
- treating
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- 239000011505 plaster Substances 0.000 title claims abstract description 55
- 206010002383 Angina Pectoris Diseases 0.000 title claims abstract description 32
- 238000002360 preparation method Methods 0.000 title claims abstract description 22
- 239000003921 oil Substances 0.000 claims abstract description 51
- 235000019198 oils Nutrition 0.000 claims abstract description 51
- 239000003814 drug Substances 0.000 claims abstract description 23
- 235000003717 Boswellia sacra Nutrition 0.000 claims abstract description 22
- 240000007551 Boswellia serrata Species 0.000 claims abstract description 22
- 235000012035 Boswellia serrata Nutrition 0.000 claims abstract description 22
- 240000007311 Commiphora myrrha Species 0.000 claims abstract description 22
- 235000006965 Commiphora myrrha Nutrition 0.000 claims abstract description 22
- 239000004863 Frankincense Substances 0.000 claims abstract description 22
- 235000007265 Myrrhis odorata Nutrition 0.000 claims abstract description 22
- DTGKSKDOIYIVQL-WEDXCCLWSA-N (+)-borneol Chemical compound C1C[C@@]2(C)[C@@H](O)C[C@@H]1C2(C)C DTGKSKDOIYIVQL-WEDXCCLWSA-N 0.000 claims abstract description 21
- REPVLJRCJUVQFA-UHFFFAOYSA-N (-)-isopinocampheol Natural products C1C(O)C(C)C2C(C)(C)C1C2 REPVLJRCJUVQFA-UHFFFAOYSA-N 0.000 claims abstract description 21
- 229940116229 borneol Drugs 0.000 claims abstract description 21
- CKDOCTFBFTVPSN-UHFFFAOYSA-N borneol Natural products C1CC2(C)C(C)CC1C2(C)C CKDOCTFBFTVPSN-UHFFFAOYSA-N 0.000 claims abstract description 21
- DTGKSKDOIYIVQL-UHFFFAOYSA-N dl-isoborneol Natural products C1CC2(C)C(O)CC1C2(C)C DTGKSKDOIYIVQL-UHFFFAOYSA-N 0.000 claims abstract description 21
- 238000002156 mixing Methods 0.000 claims abstract description 21
- 235000006040 Prunus persica var persica Nutrition 0.000 claims abstract description 13
- 244000020518 Carthamus tinctorius Species 0.000 claims abstract description 12
- 235000003255 Carthamus tinctorius Nutrition 0.000 claims abstract description 12
- 240000000774 Cunila origanoides Species 0.000 claims abstract description 12
- 235000018274 Cunila origanoides Nutrition 0.000 claims abstract description 12
- 235000014866 Dictamnus albus Nutrition 0.000 claims abstract description 12
- 239000002994 raw material Substances 0.000 claims abstract description 11
- 239000010773 plant oil Substances 0.000 claims abstract description 10
- 235000015112 vegetable and seed oil Nutrition 0.000 claims abstract description 9
- 239000008158 vegetable oil Substances 0.000 claims abstract description 9
- 244000144730 Amygdalus persica Species 0.000 claims abstract description 8
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 36
- 238000007670 refining Methods 0.000 claims description 22
- 241000304531 Allium macrostemon Species 0.000 claims description 12
- 244000061520 Angelica archangelica Species 0.000 claims description 12
- 241000758794 Asarum Species 0.000 claims description 12
- 244000037364 Cinnamomum aromaticum Species 0.000 claims description 12
- 235000014489 Cinnamomum aromaticum Nutrition 0.000 claims description 12
- 241000218176 Corydalis Species 0.000 claims description 12
- 235000001287 Guettarda speciosa Nutrition 0.000 claims description 12
- 235000008326 Trichosanthes anguina Nutrition 0.000 claims description 12
- 244000078912 Trichosanthes cucumerina Species 0.000 claims description 12
- VYQNWZOUAUKGHI-UHFFFAOYSA-N monobenzone Chemical compound C1=CC(O)=CC=C1OCC1=CC=CC=C1 VYQNWZOUAUKGHI-UHFFFAOYSA-N 0.000 claims description 12
- 239000007788 liquid Substances 0.000 claims description 8
- 238000009833 condensation Methods 0.000 claims description 7
- 230000005494 condensation Effects 0.000 claims description 7
- 238000001816 cooling Methods 0.000 claims description 7
- 238000000034 method Methods 0.000 claims description 3
- 238000003756 stirring Methods 0.000 claims description 2
- 239000000463 material Substances 0.000 claims 2
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 claims 1
- 239000010931 gold Substances 0.000 claims 1
- 229910052737 gold Inorganic materials 0.000 claims 1
- 230000000694 effects Effects 0.000 abstract description 13
- 239000002574 poison Substances 0.000 abstract description 2
- 231100000614 poison Toxicity 0.000 abstract description 2
- 230000000052 comparative effect Effects 0.000 description 9
- 208000024891 symptom Diseases 0.000 description 9
- 240000005809 Prunus persica Species 0.000 description 5
- 229940079593 drug Drugs 0.000 description 5
- 239000008280 blood Substances 0.000 description 4
- 210000004369 blood Anatomy 0.000 description 4
- 201000010099 disease Diseases 0.000 description 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 4
- 208000000059 Dyspnea Diseases 0.000 description 3
- 206010013975 Dyspnoeas Diseases 0.000 description 3
- 206010008479 Chest Pain Diseases 0.000 description 2
- AFCARXCZXQIEQB-UHFFFAOYSA-N N-[3-oxo-3-(2,4,6,7-tetrahydrotriazolo[4,5-c]pyridin-5-yl)propyl]-2-[[3-(trifluoromethoxy)phenyl]methylamino]pyrimidine-5-carboxamide Chemical compound O=C(CCNC(=O)C=1C=NC(=NC=1)NCC1=CC(=CC=C1)OC(F)(F)F)N1CC2=C(CC1)NN=N2 AFCARXCZXQIEQB-UHFFFAOYSA-N 0.000 description 2
- 206010067482 No adverse event Diseases 0.000 description 2
- 230000017531 blood circulation Effects 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 239000002674 ointment Substances 0.000 description 2
- 230000001737 promoting effect Effects 0.000 description 2
- 208000013220 shortness of breath Diseases 0.000 description 2
- 239000011800 void material Substances 0.000 description 2
- 208000019901 Anxiety disease Diseases 0.000 description 1
- 208000031229 Cardiomyopathies Diseases 0.000 description 1
- 206010009866 Cold sweat Diseases 0.000 description 1
- 206010020772 Hypertension Diseases 0.000 description 1
- 206010062717 Increased upper airway secretion Diseases 0.000 description 1
- 208000002193 Pain Diseases 0.000 description 1
- 244000131316 Panax pseudoginseng Species 0.000 description 1
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 description 1
- 235000003140 Panax quinquefolius Nutrition 0.000 description 1
- 206010040007 Sense of oppression Diseases 0.000 description 1
- 208000031975 Yang Deficiency Diseases 0.000 description 1
- 230000000202 analgesic effect Effects 0.000 description 1
- 230000000903 blocking effect Effects 0.000 description 1
- 239000000496 cardiotonic agent Substances 0.000 description 1
- 208000029078 coronary artery disease Diseases 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 238000003748 differential diagnosis Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000010579 first pass effect Methods 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 239000003205 fragrance Substances 0.000 description 1
- 235000008434 ginseng Nutrition 0.000 description 1
- 208000019622 heart disease Diseases 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 208000013210 hematogenous Diseases 0.000 description 1
- 230000001709 ictal effect Effects 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- 230000002045 lasting effect Effects 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 230000004089 microcirculation Effects 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 239000008188 pellet Substances 0.000 description 1
- 208000026435 phlegm Diseases 0.000 description 1
- 230000037452 priming Effects 0.000 description 1
- 210000004243 sweat Anatomy 0.000 description 1
- 208000011580 syndromic disease Diseases 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 230000001131 transforming effect Effects 0.000 description 1
- 238000010792 warming Methods 0.000 description 1
Classifications
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
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- A61K2236/30—Extraction of the material
- A61K2236/35—Extraction with lipophilic solvents, e.g. Hexane or petrol ether
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Abstract
The invention discloses a kind of plaster and preparation method thereof for treating chest impediment and cardialgia, which includes the raw material of following parts by weight：10 45 parts of peach kernel, 10 45 parts of safflower, 10 60 parts of dittany bark, 10 45 parts of frankincense, 8 45 parts of myrrh, 10 60 parts of radix paeoniae rubra, 10 60 parts of Rhizoma Chuanxiong etc..Preparation method includes：(1) frankincense, myrrh, Radix Salviae Miltiorrhizae and borneol are crushed, mixing, crosses 100 150 mesh sieve；(2) surplus stock is placed in vegetable oil, plant oil temperature is appreciated 320 330 DEG C in 2 3h, prepare medicine oil；(3) when step (2) gained medicine oil temperature is down to 280 300 DEG C, red lead is added, finally goes " fiery poison "；(4) melt, mixed with step (1) gains, booth is made on blank plaster.Plaster produced by the present invention, easy to use, curative effect time is short, and effect is good, and is free from side effects, and can effectively treat chest impediment and cardialgia illness.
Description
Technical field
The invention belongs to traditional Chinese medicine plaster technical fields, and in particular to a kind of plaster and its preparation for treating chest impediment and cardialgia
Method.
Background technology
Chest impediment and cardialgia is one of the important disease of heart system for threatening middle-aged and the old's life and health, the accidental of short duration slight chest of less serious case
Portion's oppressiveness or secret anguish, or be ictal Danzhong or the unclean sense of discomfort of left chest；Severe one sharp ache, or twisted in squeezing sample
Bitterly.It is often accompanied by palpitaition, shortness of breath, unsmooth breath or even syndrome characterized by dyspnea, terrified uneasy, pale complexion, cold sweat goes out certainly.Disease this void mark
Real, this void is mainly the heart-yang deficiency of vital energy, pushes inability, hematogenous blockage, stasis blocking water is caused to stop.With modern society's life mode and drink
The change of structure is eaten, morbidity has the tendency that gradually increasing, thus this disease increasingly attracts people's attention.But use existing medicine
It is long, ineffective there are treatment time when object treats chest impediment and cardialgia, at the same also side effect the problem of.
Invention content
For above-mentioned deficiency in the prior art, the present invention provides a kind of plaster and its system for treating chest impediment and cardialgia
Preparation Method can effectively solve the drug of existing treatment chest impediment and cardialgia, and treatment time is long, ineffective while also side effect
Problem.
To achieve the above object, the technical solution adopted by the present invention to solve the technical problems is：
A kind of plaster for treating chest impediment and cardialgia includes the raw material of following parts by weight：10-45 parts of peach kernel, safflower 10-45
Part, 10-60 parts of dittany bark, 10-45 parts of frankincense, 8-45 parts of myrrh, 10-60 parts of radix paeoniae rubra, 10-60 parts of Rhizoma Chuanxiong, 10-60 parts of Radix Salviae Miltiorrhizae,
10-45 parts of the root of Dahurain angelica, 3-18 parts of asarum, 6-36 parts of cassia twig, 8-45 parts of Snakegourd Seed, 10-60 parts of Longstamen Onion Bulb, 8-45 parts of rhizoma cyperi, Fructus Aurantii 8-
4-24 parts of 45 parts, 10-60 parts of corydalis tuber, 8-45 parts of Radix Curcumae, 10-60 parts of Radix Paeoniae Alba and borneol.
Further, a kind of plaster for treating chest impediment and cardialgia, includes the raw material of following parts by weight：12-30 parts of peach kernel,
12-30 parts of safflower, 15-50 parts of dittany bark, 12-35 parts of frankincense, 12-25 parts of myrrh, 15-40 parts of radix paeoniae rubra, 15-40 parts of Rhizoma Chuanxiong, pellet
10-30 parts of ginseng, 12-30 parts of the root of Dahurain angelica, 5-10 parts of asarum, 8-25 parts of cassia twig, 12-30 parts of Snakegourd Seed, 15-30 parts of Longstamen Onion Bulb, rhizoma cyperi 12-
6-12 parts of 25 parts, 12-30 parts of Fructus Aurantii, 15-30 parts of corydalis tuber, 12-25 parts of Radix Curcumae, 15-35 parts of Radix Paeoniae Alba and borneol.
Further, a kind of plaster for treating chest impediment and cardialgia, includes the raw material of following parts by weight：It is 15 parts of peach kernel, red
Spend 15 parts, 20 parts of dittany bark, 15 parts of frankincense, 15 parts of myrrh, 20 parts of radix paeoniae rubra, 20 parts of Rhizoma Chuanxiong, 20 parts of Radix Salviae Miltiorrhizae, 15 parts of the root of Dahurain angelica, asarum 6
Part, 12 parts of cassia twig, 15 parts of Snakegourd Seed, 20 parts of Longstamen Onion Bulb, 15 parts of rhizoma cyperi, 15 parts of Fructus Aurantii, 20 parts of corydalis tuber, 15 parts of Radix Curcumae, Radix Paeoniae Alba 20
8 parts of part and borneol.
The above-mentioned preparation method for treating the plaster of chest impediment and cardialgia includes the following steps：
(1) frankincense, myrrh, Radix Salviae Miltiorrhizae and borneol are crushed respectively, mixing, then crosses 100-150 mesh sieve；
(2) surplus stock is respectively placed in vegetable oil, plant oil temperature is then risen to 320-330 DEG C in 2-3h,
Then it refines oil, is filtered after oil refining, remove the dregs of a decoction, obtain medicine oil；Wherein oil refining can terminate to following degree：By gained
Medicine oil instills in water, after oil bloom scatter and can assemble, oil refining terminates；
(3) when step (2) gained medicine oil temperature is down to 280-300 DEG C, red lead is added, is stirred when adding red lead, so
It is poured into water afterwards with thread, continues to stir and evenly mix, taken out after its cooling condensation, rub repeatedly, agglomerate is made, finally by agglomerate
12-16 days are stood into the water, changes water twice daily, is gone to the greatest extent " fiery poison "；
(4) step (3) gains water proof is heated, so that it is melted the moisture in simultaneously removal step (3) gains, then adds
Enter step (1) gains, mixing places it on blank plaster, is made.
Further, in step (2), plant oil temperature is risen to 320 DEG C in 3h.
Further, in step (3), time of repose is 14 days.
Provided by the present invention for treating the plaster and preparation method thereof of chest impediment and cardialgia, have the advantages that：
(1) peach kernel, safflower, frankincense, myrrh, radix paeoniae rubra, Rhizoma Chuanxiong, Radix Salviae Miltiorrhizae are promoting blood circulation and removing blood stasis in inventive formulation；Snakegourd Seed, Longstamen Onion Bulb
Reducing phlegm and resolving masses；Cassia twig helps yang transforming qi, temperature three-way meridian；Rhizoma cyperi, Fructus Aurantii, corydalis tuber, Radix Curcumae, Radix Paeoniae Alba, the analgesic of root of Dahurain angelica chest qi；In vain
Moss skin cardiac stimulant；Asarum is warded off the cold to be drunk by phlegmization；Borneol fragrance is walked to alter, priming uplink；These drugs combine, and pass through specific method
Plaster is prepared, which can be promoting blood circulation and removing blood stasis, warming heart yang, so as to improve microcirculation, reduces blood viscosity, and then effectively
Treat chest impediment and cardialgia illness.
(2) plaster produced by the present invention, treatment are to be directed to patient illness part dispenser, are formed in disease sites higher
Drug concentration, selectivity and specific aim are stronger, to can avoid toxic side effect of the drug first pass effect to liver and other organs, because
This, plaster of the present invention is safe and reliable.
(3) plaster produced by the present invention, easy to use, curative effect time is short, and effect is good, and is free from side effects.
Specific implementation mode
Embodiment 1
A kind of plaster for treating chest impediment and cardialgia includes the raw material of following parts by weight：Peach kernel 10g, safflower 10g, dittany
Skin 10g, frankincense 10g, myrrh 8g, radix paeoniae rubra 10g, Rhizoma Chuanxiong 10g, Radix Salviae Miltiorrhizae 10g, root of Dahurain angelica 10g, asarum 3g, cassia twig 6g, Snakegourd Seed 8g,
Longstamen Onion Bulb 10g, rhizoma cyperi 8g, Fructus Aurantii 8g, corydalis tuber 10g, Radix Curcumae 8g, Radix Paeoniae Alba 10g and borneol 4g.
The above-mentioned preparation method for treating the plaster of chest impediment and cardialgia includes the following steps：
(1) frankincense, myrrh, Radix Salviae Miltiorrhizae and borneol are crushed respectively, then mixing sieves with 100 mesh sieve；
(2) surplus stock is placed in 4200g vegetable oil, plant oil temperature is risen to 320 DEG C in 2h, is then refined oil,
It is filtered after oil refining, removes the dregs of a decoction, obtain medicine oil；Wherein oil refining can terminate to following degree：The medicine oil of gained is instilled
In water, after oil bloom scatter and it can assemble, oil refining terminates；
(3) when step (2) gains temperature is down to 280 DEG C, 1020g red lead is added, is stirred to shape when adding red lead
It at black stiff shape liquid, is then poured into cold water, is stirred continuously with thread, taken out after its cooling condensation, rub, make repeatedly
At agglomerate, agglomerate is finally stood to 12 days into the water, changes water twice daily；
(4) step (3) gains water proof is heated, so that it is melted the moisture in simultaneously removal step (3) gains, then adds
Enter step (1) gains, mixing places it on blank plaster, is made, every net weight 30g of the plaster.
Embodiment 2
A kind of plaster for treating chest impediment and cardialgia includes the raw material of following parts by weight：Peach kernel 45g, safflower 45g, dittany
Skin 60g, frankincense 45g, myrrh 45g, radix paeoniae rubra 60g, Rhizoma Chuanxiong 60g, Radix Salviae Miltiorrhizae 60g, root of Dahurain angelica 45g, asarum 18g, cassia twig 36g, Snakegourd Seed
45g, Longstamen Onion Bulb 60g, rhizoma cyperi 45g, Fructus Aurantii 45g, corydalis tuber 60g, Radix Curcumae 45g, Radix Paeoniae Alba 60g and borneol 24g.
The above-mentioned preparation method for treating the plaster of chest impediment and cardialgia includes the following steps：
(1) frankincense, myrrh, Radix Salviae Miltiorrhizae and borneol are crushed respectively, mixing, then crosses 150 mesh sieve；
(2) surplus stock is placed in 4300g vegetable oil, plant oil temperature is risen to 330 DEG C in 3h, is then refined oil,
It is filtered after oil refining, removes the dregs of a decoction, obtain medicine oil；Wherein oil refining can terminate to following degree：The medicine oil of gained is instilled
In water, after oil bloom scatter and it can assemble, oil refining terminates；
(3) when step (2) gains temperature is down to 300 DEG C, 1100g red lead is added, is stirred to shape when adding red lead
It at black stiff shape liquid, is then poured into cold water, is stirred continuously with thread, taken out after its cooling condensation, rub, make repeatedly
At agglomerate, agglomerate is finally stood to 16 days into the water, changes water twice daily；
(4) step (3) gains water proof is heated, so that it is melted the moisture in simultaneously removal step (3) gains, then adds
Enter step (1) gains, mixing places it on blank plaster, is made, every net weight 30g of the plaster.
Embodiment 3
A kind of plaster for treating chest impediment and cardialgia includes the raw material of following parts by weight：Peach kernel 12g, safflower 12g, dittany
Skin 15g, frankincense 12g, myrrh 12g, radix paeoniae rubra 15g, Rhizoma Chuanxiong 15g, Radix Salviae Miltiorrhizae 10g, root of Dahurain angelica 12g, asarum 5g, cassia twig 8g, Snakegourd Seed
12g, Longstamen Onion Bulb 15g, rhizoma cyperi 12g, Fructus Aurantii 12g, corydalis tuber 15g, Radix Curcumae 12g, Radix Paeoniae Alba 15g and borneol 6g.
The above-mentioned preparation method for treating the plaster of chest impediment and cardialgia includes the following steps：
(1) frankincense, myrrh, Radix Salviae Miltiorrhizae and borneol are crushed respectively, mixing, then crosses 150 mesh sieve；
(2) surplus stock is placed in 4250g vegetable oil, plant oil temperature is risen to 320 DEG C in 3h, is then refined oil,
It is filtered after oil refining, removes the dregs of a decoction, obtain medicine oil；Wherein oil refining can terminate to following degree：The medicine oil of gained is instilled
In water, after oil bloom scatter and it can assemble, oil refining terminates；
(3) when step (2) gains temperature is down to 300 DEG C, 1030g red lead is added, is stirred to shape when adding red lead
It at black stiff shape liquid, is then poured into cold water, is stirred continuously with thread, taken out after its cooling condensation, rub, make repeatedly
At agglomerate, agglomerate is finally stood to 13 days into the water, changes water twice daily；
(4) step (3) gains water proof is heated, so that it is melted the moisture in simultaneously removal step (3) gains, then adds
Enter step (1) gains, mixing places it on blank plaster, is made, every net weight 30g of the plaster.
Embodiment 4
A kind of plaster for treating chest impediment and cardialgia includes the raw material of following parts by weight：Peach kernel 30g, safflower 30g, dittany
Skin 50g, frankincense 35g, myrrh 25g, radix paeoniae rubra 40g, Rhizoma Chuanxiong 40g, Radix Salviae Miltiorrhizae 30g, root of Dahurain angelica 30g, asarum 10g, cassia twig 25g, Snakegourd Seed
30g, Longstamen Onion Bulb 30g, rhizoma cyperi 25g, Fructus Aurantii 30g, corydalis tuber 30g, Radix Curcumae 25g, Radix Paeoniae Alba 35g and borneol 12g.
The above-mentioned preparation method for treating the plaster of chest impediment and cardialgia includes the following steps：
(1) frankincense, myrrh, Radix Salviae Miltiorrhizae and borneol are crushed respectively, mixing, then crosses 150 mesh sieve；
(2) surplus stock is placed in 4280g vegetable oil, plant oil temperature is risen to 320 DEG C in 3h, is then refined oil,
It is filtered after oil refining, removes the dregs of a decoction, obtain medicine oil；Wherein oil refining can terminate to following degree：The medicine oil of gained is instilled
In water, after oil bloom scatter and it can assemble, oil refining terminates；
(3) when step (2) gains temperature is down to 300 DEG C, 1080g red lead is added, is stirred to shape when adding red lead
It at black stiff shape liquid, is then poured into cold water, is stirred continuously with thread, taken out after its cooling condensation, rub, make repeatedly
At agglomerate, agglomerate is finally stood to 15 days into the water, changes water twice daily；
(4) step (3) gains water proof is heated, so that it is melted the moisture in simultaneously removal step (3) gains, then adds
Enter step (1) gains, mixing places it on blank plaster, is made, every net weight 30g of the plaster.
Embodiment 5
A kind of plaster for treating chest impediment and cardialgia includes the raw material of following parts by weight：Peach kernel 15g, safflower 15g, dittany
Skin 20g, frankincense 15g, myrrh 15g, radix paeoniae rubra 20g, Rhizoma Chuanxiong 20g, Radix Salviae Miltiorrhizae 20g, root of Dahurain angelica 15g, asarum 6g, cassia twig 12g, Snakegourd Seed
15g, Longstamen Onion Bulb 20g, rhizoma cyperi 15g, Fructus Aurantii 15g, corydalis tuber 20g, Radix Curcumae 15g, Radix Paeoniae Alba 20g and borneol 8g.
The above-mentioned preparation method for treating the plaster of chest impediment and cardialgia includes the following steps：
(1) frankincense, myrrh, Radix Salviae Miltiorrhizae and borneol are crushed respectively, mixing, then crosses 150 mesh sieve；
(2) surplus stock is placed in 4255g vegetable oil, plant oil temperature is risen to 320 DEG C in 3h, is then refined oil,
It is filtered after oil refining, removes the dregs of a decoction, obtain medicine oil；Wherein oil refining can terminate to following degree：The medicine oil of gained is instilled
In water, after oil bloom scatter and it can assemble, oil refining terminates；
(3) when step (2) gains temperature is down to 300 DEG C, 1051g red lead is added, is stirred to shape when adding red lead
It at black stiff shape liquid, is then poured into cold water, is stirred continuously with thread, taken out after its cooling condensation, rub, make repeatedly
At agglomerate, agglomerate is finally stood to 14 days into the water, changes water twice daily；
(4) step (3) gains water proof is heated, so that it is melted the moisture in simultaneously removal step (3) gains, then adds
Enter step (1) gains, mixing places it on blank plaster, is made, every net weight 30g of the plaster.
Comparative example 1
1 difference from Example 5 of comparative example is, in preparation process step (3), step (2) gains temperature is dropped
When to 300 DEG C, 1051g red lead is added, is stirred when adding red lead to black stiff shape liquid is formed, step (1) is then added
Gains, mixing place it on blank plaster, and plaster, every net weight 30g of the plaster is made.
Comparative example 2
2 difference from Example 5 of comparative example is preparation process difference, and raw material components are identical, and preparation process includes
Following steps：
(1) frankincense, myrrh, Radix Salviae Miltiorrhizae and borneol are crushed respectively, mixing, then crosses 150 mesh sieve；
(2) surplus stock is also crushed respectively, mixing, then crosses 150 mesh sieve；
(3) 4255g vegetable oil is heated to 60 DEG C, stops heating, step (2) gains are then added, mixing adds
Step (1) gains, mixing are made ointment, gained ointment are placed on blank plaster, and plaster is made, and every, the plaster is net
Weight 30g.
Test example
Patient and symptom：Feeling of oppression and pain in the chest caused by random inspection hypertension, coronary heart disease, cardiomyopathy, valvulopathy etc. is suffered from
Person 210, it belongs to stagnation of blood stasis disease person to differential diagnosis in tcm, and symptom is uncomfortable in chest, pectoralgia, shortness of breath, weak, palpitaition, pale complexion, goes out
Sweat limb is cold etc..
Grouping：These patients are randomly divided into 7 groups, 1-7 groups difference corresponding embodiment 1-5 and comparative example 1-2.
Suggested use and dosage：It will be wiped clean at patient's pareordia or chest pain, then plaster heated and is softened, before being affixed on the heart
At area or chest pain, daily to paste 1-2 pieces, every lasting 8h, 7 days as a course for the treatment of.
Effect：Treated using plaster made from embodiment 1-5 and comparative example 1-2, used respectively 3 courses for the treatment of, 2
When the course for the treatment of, 2 courses for the treatment of, 2 courses for the treatment of, 1 course for the treatment of and 3 courses for the treatment of, 3 courses for the treatment of, the patient feels symptom is substantially reduced, embodiment 1-
5 are further continued for that a course for the treatment of, symptom is used obviously to disappear, do not recur in 1 year, and have no adverse reaction；And comparative example 1 need to be after
It is continuous that 2 courses for the treatment of, symptom is used obviously to disappear, do not recurred in 1 year, and have no adverse reaction；And 2 comparative example 1 of comparative example need to be after
It is continuous that 2 courses for the treatment of, symptom is used obviously to disappear, it will appear light symptoms once in a while in 1 year.
In conclusion using plaster made from formula provided by the invention and specific preparation process, patient is easy to use,
After use in a short time can substantially reduced symptom, only according to formula provided by the invention combine specific preparation method,
Effect is just apparent, and curative effect time is short, and symptom is uneasy to recur, and side effect will not be generated to patient.
Claims (7)
1. a kind of plaster for treating chest impediment and cardialgia, which is characterized in that include the raw material of following parts by weight：10-45 parts of peach kernel,
10-45 parts of safflower, 10-60 parts of dittany bark, 10-45 parts of frankincense, 8-45 parts of myrrh, 10-60 parts of radix paeoniae rubra, 10-60 parts of Rhizoma Chuanxiong, Radix Salviae Miltiorrhizae
10-60 parts, 10-45 parts of the root of Dahurain angelica, 3-18 parts of asarum, 6-36 parts of cassia twig, 8-45 parts of Snakegourd Seed, 10-60 parts of Longstamen Onion Bulb, rhizoma cyperi 8-45
4-24 parts of part, 8-45 parts of Fructus Aurantii, 10-60 parts of corydalis tuber, 8-45 parts of Radix Curcumae, 10-60 parts of Radix Paeoniae Alba and borneol.
2. the plaster according to claim 1 for treating chest impediment and cardialgia, which is characterized in that include the original of following parts by weight
Material：12-30 parts of peach kernel, 12-30 parts of safflower, 15-50 parts of dittany bark, 12-35 parts of frankincense, 12-25 parts of myrrh, 15-40 parts of radix paeoniae rubra,
15-40 parts of Rhizoma Chuanxiong, 10-30 parts of Radix Salviae Miltiorrhizae, 12-30 parts of the root of Dahurain angelica, 5-10 parts of asarum, 8-25 parts of cassia twig, 12-30 parts of Snakegourd Seed, Longstamen Onion Bulb
15-30 parts, 12-25 parts of rhizoma cyperi, 12-30 parts of Fructus Aurantii, 15-30 parts of corydalis tuber, 12-25 parts of Radix Curcumae, 15-35 parts of Radix Paeoniae Alba and borneol 6-
12 parts.
3. the plaster according to claim 2 for treating chest impediment and cardialgia, which is characterized in that include the original of following parts by weight
Material：15 parts of peach kernel, 15 parts of safflower, 20 parts of dittany bark, 15 parts of frankincense, 15 parts of myrrh, 20 parts of radix paeoniae rubra, 20 parts of Rhizoma Chuanxiong, 20 parts of Radix Salviae Miltiorrhizae,
It is 15 parts of the root of Dahurain angelica, 6 parts of asarum, 12 parts of cassia twig, 15 parts of Snakegourd Seed, 20 parts of Longstamen Onion Bulb, 15 parts of rhizoma cyperi, 15 parts of Fructus Aurantii, 20 parts of corydalis tuber, strongly fragrant
8 parts of 15 parts of gold, 20 parts of Radix Paeoniae Alba and borneol.
4. the preparation method as described in any one of claims 1-3 for treating the plaster of chest impediment and cardialgia, which is characterized in that packet
Include following steps：
(1) frankincense, myrrh, Radix Salviae Miltiorrhizae and borneol are crushed respectively, mixing, then crosses 100-150 mesh sieve；
(2) surplus stock is respectively placed in vegetable oil, plant oil temperature is then risen to 320-330 DEG C in 2-3h, then
Oil refining, filters after oil refining, removes the dregs of a decoction, obtain medicine oil；
(3) when step (2) gained medicine oil temperature is down to 280-300 DEG C, red lead is added, is stirred when adding red lead, after mixing
It is placed in water, continues to stir and evenly mix, taken out after its cooling condensation, rub repeatedly, agglomerate is made, into the water by agglomerate finally
12-16 days are stood, changes water twice daily；
(4) step (3) gains water proof is heated, so that it is melted the moisture in simultaneously removal step (3) gains, step is then added
Suddenly (1) gains, mixing place it on blank plaster, are made.
5. the preparation method according to claim 4 for treating the plaster of chest impediment and cardialgia, which is characterized in that step (2)
In, plant oil temperature is risen to 320 DEG C in 3h.
6. the preparation method according to claim 4 for treating the plaster of chest impediment and cardialgia, which is characterized in that step (2)
In, index that oil refining process terminates is that the liquid of gained after refining oil instills in water, after liquid scatters and can be flocked together.
7. the preparation method according to claim 4 for treating the plaster of chest impediment and cardialgia, which is characterized in that step (3)
In, time of repose is 14 days.
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| CN201810379021.7A CN108452255A (en) | 2018-04-25 | 2018-04-25 | Plaster and preparation method thereof for treating chest impediment and cardialgia |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109125693A (en) * | 2018-09-28 | 2019-01-04 | 周妍 | For improving the Chinese herbal medicine of myocardial blood supply, drug paste and the preparation method of drug paste |
| CN114470049A (en) * | 2022-02-24 | 2022-05-13 | 重庆市垫江县人民医院 | Plaster for treating blood stasis arthralgia and preparation and use methods thereof |
-
2018
- 2018-04-25 CN CN201810379021.7A patent/CN108452255A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109125693A (en) * | 2018-09-28 | 2019-01-04 | 周妍 | For improving the Chinese herbal medicine of myocardial blood supply, drug paste and the preparation method of drug paste |
| CN114470049A (en) * | 2022-02-24 | 2022-05-13 | 重庆市垫江县人民医院 | Plaster for treating blood stasis arthralgia and preparation and use methods thereof |
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Application publication date: 20180828 |