CN108450953A - A method of protection eyesight - Google Patents
A method of protection eyesight Download PDFInfo
- Publication number
- CN108450953A CN108450953A CN201810256261.8A CN201810256261A CN108450953A CN 108450953 A CN108450953 A CN 108450953A CN 201810256261 A CN201810256261 A CN 201810256261A CN 108450953 A CN108450953 A CN 108450953A
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- CN
- China
- Prior art keywords
- purity
- yeast
- brewer
- lutein ester
- oligofructose
- Prior art date
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- Pending
Links
- 238000000034 method Methods 0.000 title claims abstract description 20
- 230000004438 eyesight Effects 0.000 title claims abstract description 14
- 240000004808 Saccharomyces cerevisiae Species 0.000 claims abstract description 20
- 235000014680 Saccharomyces cerevisiae Nutrition 0.000 claims abstract description 20
- KBPHJBAIARWVSC-RGZFRNHPSA-N lutein Chemical compound C([C@H](O)CC=1C)C(C)(C)C=1\C=C\C(\C)=C\C=C\C(\C)=C\C=C\C=C(/C)\C=C\C=C(/C)\C=C\[C@H]1C(C)=C[C@H](O)CC1(C)C KBPHJBAIARWVSC-RGZFRNHPSA-N 0.000 claims abstract description 17
- 239000000047 product Substances 0.000 claims abstract description 14
- WHMDKBIGKVEYHS-IYEMJOQQSA-L Zinc gluconate Chemical compound [Zn+2].OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O WHMDKBIGKVEYHS-IYEMJOQQSA-L 0.000 claims abstract description 13
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 13
- 239000011670 zinc gluconate Substances 0.000 claims abstract description 13
- 235000011478 zinc gluconate Nutrition 0.000 claims abstract description 13
- 229960000306 zinc gluconate Drugs 0.000 claims abstract description 13
- 238000004806 packaging method and process Methods 0.000 claims abstract description 8
- 238000012545 processing Methods 0.000 claims abstract description 8
- 239000002994 raw material Substances 0.000 claims abstract description 7
- 238000010438 heat treatment Methods 0.000 claims abstract description 4
- 238000011068 loading method Methods 0.000 claims abstract description 4
- 230000001954 sterilising effect Effects 0.000 claims abstract description 4
- 238000004659 sterilization and disinfection Methods 0.000 claims abstract description 4
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 claims description 18
- LRHPLDYGYMQRHN-UHFFFAOYSA-N N-Butanol Chemical compound CCCCO LRHPLDYGYMQRHN-UHFFFAOYSA-N 0.000 claims description 18
- 241000209140 Triticum Species 0.000 claims description 18
- 235000021307 Triticum Nutrition 0.000 claims description 18
- 238000000855 fermentation Methods 0.000 claims description 18
- 230000004151 fermentation Effects 0.000 claims description 18
- 235000011389 fruit/vegetable juice Nutrition 0.000 claims description 18
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 claims description 12
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 12
- XLOMVQKBTHCTTD-UHFFFAOYSA-N Zinc monoxide Chemical compound [Zn]=O XLOMVQKBTHCTTD-UHFFFAOYSA-N 0.000 claims description 12
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Chemical compound OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims description 6
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 claims description 6
- 238000009835 boiling Methods 0.000 claims description 6
- 235000013339 cereals Nutrition 0.000 claims description 6
- 239000012141 concentrate Substances 0.000 claims description 6
- 239000012065 filter cake Substances 0.000 claims description 6
- 230000002218 hypoglycaemic effect Effects 0.000 claims description 6
- 238000004519 manufacturing process Methods 0.000 claims description 6
- IJDNQMDRQITEOD-UHFFFAOYSA-N sec-butylidene Natural products CCCC IJDNQMDRQITEOD-UHFFFAOYSA-N 0.000 claims description 6
- 238000003756 stirring Methods 0.000 claims description 6
- UGZADUVQMDAIAO-UHFFFAOYSA-L zinc hydroxide Chemical compound [OH-].[OH-].[Zn+2] UGZADUVQMDAIAO-UHFFFAOYSA-L 0.000 claims description 6
- 229940007718 zinc hydroxide Drugs 0.000 claims description 6
- 229910021511 zinc hydroxide Inorganic materials 0.000 claims description 6
- 239000011787 zinc oxide Substances 0.000 claims description 6
- 239000008103 glucose Substances 0.000 claims description 5
- 239000012452 mother liquor Substances 0.000 claims description 5
- 239000003963 antioxidant agent Substances 0.000 claims description 4
- 230000003078 antioxidant effect Effects 0.000 claims description 4
- 235000006708 antioxidants Nutrition 0.000 claims description 4
- 238000001914 filtration Methods 0.000 claims description 4
- 239000007788 liquid Substances 0.000 claims description 4
- 230000003647 oxidation Effects 0.000 claims description 4
- 238000007254 oxidation reaction Methods 0.000 claims description 4
- NWUYHJFMYQTDRP-UHFFFAOYSA-N 1,2-bis(ethenyl)benzene;1-ethenyl-2-ethylbenzene;styrene Chemical compound C=CC1=CC=CC=C1.CCC1=CC=CC=C1C=C.C=CC1=CC=CC=C1C=C NWUYHJFMYQTDRP-UHFFFAOYSA-N 0.000 claims description 3
- AEQDJSLRWYMAQI-UHFFFAOYSA-N 2,3,9,10-tetramethoxy-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinoline Chemical compound C1CN2CC(C(=C(OC)C=C3)OC)=C3CC2C2=C1C=C(OC)C(OC)=C2 AEQDJSLRWYMAQI-UHFFFAOYSA-N 0.000 claims description 3
- 241000228212 Aspergillus Species 0.000 claims description 3
- 235000005881 Calendula officinalis Nutrition 0.000 claims description 3
- RGHNJXZEOKUKBD-UHFFFAOYSA-N D-gluconic acid Natural products OCC(O)C(O)C(O)C(O)C(O)=O RGHNJXZEOKUKBD-UHFFFAOYSA-N 0.000 claims description 3
- RGHNJXZEOKUKBD-SQOUGZDYSA-N Gluconic acid Natural products OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O RGHNJXZEOKUKBD-SQOUGZDYSA-N 0.000 claims description 3
- 208000007976 Ketosis Diseases 0.000 claims description 3
- FLDFNEBHEXLZRX-DLQNOBSRSA-N Nystose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)OC[C@]1(OC[C@]2(O[C@@H]3[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O3)O)[C@H]([C@H](O)[C@@H](CO)O2)O)[C@@H](O)[C@H](O)[C@@H](CO)O1 FLDFNEBHEXLZRX-DLQNOBSRSA-N 0.000 claims description 3
- 240000000111 Saccharum officinarum Species 0.000 claims description 3
- 235000007201 Saccharum officinarum Nutrition 0.000 claims description 3
- 229930006000 Sucrose Natural products 0.000 claims description 3
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 claims description 3
- 240000000785 Tagetes erecta Species 0.000 claims description 3
- 239000002253 acid Substances 0.000 claims description 3
- 239000004480 active ingredient Substances 0.000 claims description 3
- 239000003463 adsorbent Substances 0.000 claims description 3
- 239000003472 antidiabetic agent Substances 0.000 claims description 3
- 235000013405 beer Nutrition 0.000 claims description 3
- 239000003729 cation exchange resin Substances 0.000 claims description 3
- 238000011049 filling Methods 0.000 claims description 3
- 239000000174 gluconic acid Substances 0.000 claims description 3
- 235000012208 gluconic acid Nutrition 0.000 claims description 3
- 229940126904 hypoglycaemic agent Drugs 0.000 claims description 3
- 239000012535 impurity Substances 0.000 claims description 3
- 150000002584 ketoses Chemical class 0.000 claims description 3
- 239000000203 mixture Substances 0.000 claims description 3
- FLDFNEBHEXLZRX-UHFFFAOYSA-N nystose Natural products OC1C(O)C(CO)OC1(CO)OCC1(OCC2(OC3C(C(O)C(O)C(CO)O3)O)C(C(O)C(CO)O2)O)C(O)C(O)C(CO)O1 FLDFNEBHEXLZRX-UHFFFAOYSA-N 0.000 claims description 3
- 238000002360 preparation method Methods 0.000 claims description 3
- 238000005086 pumping Methods 0.000 claims description 3
- 238000010583 slow cooling Methods 0.000 claims description 3
- 239000000176 sodium gluconate Substances 0.000 claims description 3
- 235000012207 sodium gluconate Nutrition 0.000 claims description 3
- 229940005574 sodium gluconate Drugs 0.000 claims description 3
- 239000002904 solvent Substances 0.000 claims description 3
- 239000005720 sucrose Substances 0.000 claims description 3
- 238000005406 washing Methods 0.000 claims description 3
- RFSUNEUAIZKAJO-ARQDHWQXSA-N Fructose Chemical class OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O RFSUNEUAIZKAJO-ARQDHWQXSA-N 0.000 claims 1
- 239000000284 extract Substances 0.000 claims 1
- 238000009434 installation Methods 0.000 claims 1
- 238000002156 mixing Methods 0.000 claims 1
- 238000010025 steaming Methods 0.000 claims 1
- 235000016709 nutrition Nutrition 0.000 abstract description 7
- 230000035764 nutrition Effects 0.000 abstract description 7
- 230000003064 anti-oxidating effect Effects 0.000 abstract description 4
- 238000012856 packing Methods 0.000 abstract description 3
- 239000003755 preservative agent Substances 0.000 abstract description 3
- 230000002335 preservative effect Effects 0.000 abstract description 3
- 239000013589 supplement Substances 0.000 abstract description 3
- 238000005457 optimization Methods 0.000 description 5
- 230000008859 change Effects 0.000 description 3
- 239000011701 zinc Substances 0.000 description 3
- 229910052725 zinc Inorganic materials 0.000 description 3
- FPIPGXGPPPQFEQ-UHFFFAOYSA-N 13-cis retinol Natural products OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-UHFFFAOYSA-N 0.000 description 2
- FPIPGXGPPPQFEQ-BOOMUCAASA-N Vitamin A Natural products OC/C=C(/C)\C=C\C=C(\C)/C=C/C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-BOOMUCAASA-N 0.000 description 2
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 description 2
- FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 description 2
- 238000000605 extraction Methods 0.000 description 2
- 230000036541 health Effects 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 150000003254 radicals Chemical class 0.000 description 2
- 235000019155 vitamin A Nutrition 0.000 description 2
- 239000011719 vitamin A Substances 0.000 description 2
- 229940045997 vitamin a Drugs 0.000 description 2
- NAOLWIGVYRIGTP-UHFFFAOYSA-N 1,3,5-trihydroxyanthracene-9,10-dione Chemical compound C1=CC(O)=C2C(=O)C3=CC(O)=CC(O)=C3C(=O)C2=C1 NAOLWIGVYRIGTP-UHFFFAOYSA-N 0.000 description 1
- 201000004569 Blindness Diseases 0.000 description 1
- 208000002177 Cataract Diseases 0.000 description 1
- 206010019233 Headaches Diseases 0.000 description 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
- 241001025261 Neoraja caerulea Species 0.000 description 1
- 208000017442 Retinal disease Diseases 0.000 description 1
- 206010038923 Retinopathy Diseases 0.000 description 1
- 206010047571 Visual impairment Diseases 0.000 description 1
- 235000009754 Vitis X bourquina Nutrition 0.000 description 1
- 235000012333 Vitis X labruscana Nutrition 0.000 description 1
- 240000006365 Vitis vinifera Species 0.000 description 1
- 235000014787 Vitis vinifera Nutrition 0.000 description 1
- 230000032683 aging Effects 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- QNDQILQPPKQROV-UHFFFAOYSA-N dizinc Chemical compound [Zn]=[Zn] QNDQILQPPKQROV-UHFFFAOYSA-N 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 208000027993 eye symptom Diseases 0.000 description 1
- 231100000869 headache Toxicity 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 230000003902 lesion Effects 0.000 description 1
- 230000037345 metabolism of vitamins Effects 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 230000000149 penetrating effect Effects 0.000 description 1
- 230000005855 radiation Effects 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 208000029257 vision disease Diseases 0.000 description 1
- 230000004393 visual impairment Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/125—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives containing carbohydrate syrups; containing sugars; containing sugar alcohols; containing starch hydrolysates
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/14—Yeasts or derivatives thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/16—Inorganic salts, minerals or trace elements
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
- C07C403/24—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by six-membered non-aromatic rings, e.g. beta-carotene
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/14—Fungi; Culture media therefor
- C12N1/16—Yeasts; Culture media therefor
- C12N1/18—Baker's yeast; Brewer's yeast
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
- C12P7/58—Aldonic, ketoaldonic or saccharic acids
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Abstract
The invention discloses a kind of methods of protection eyesight, and specific method includes as follows, S1, makes the lutein ester of high-purity first；S2 makes the brewer's yeast of high-purity；S3 makes the zinc gluconate of high-purity；S4 makes the oligofructose of high-purity；S5, the above zinc gluconate and oligofructose are mixed, then lutein ester is first poured into be heated, computer heating control temperature is at 85 120 DEG C, and time control is in 45min, when being cooled to room temperature, it is then slowly added into brewer's yeast, it is thoroughly mixed, then the 20min that simmers in water is to get finished product；S6, raw material packaging：The finished product processed is subjected to disinfection by ultraviolet light, then the good solution of sterilizing is fitted into bottled packing machine, by being fitted into Packaging Bottle according to fixed weight, every bottle of 15 30ml after the completion of loading, are integrally sealed processing.The nutrition of the product supplement ocular cell of the method for the present invention processing, increases its antioxidation, is convenient for carrying, nutrition is delicious, additive-free, preservative free.
Description
Technical field
The present invention relates to technical field of medical science, especially a kind of method of protection eyesight.
Background technology
With electronic digital model change, viewing custom (such as viewing distance, display brightness and the display colour temperature of spectators
Deng) do not change but.But electronic digital product is used to health science, needs the brightness according to different electronic digital products, spoke
Situations such as penetrating adjusts viewing distance and viewing duration of spectators etc..Electronic digital product in the prior art does not remind spectators
Abstemiously, it scientifically watches, causes many spectators visual impairment, Headache due to long-time, short distance viewing use
The eye symptoms such as puckery, and the arch-criminal of eyes aging is mainly the destruction of free radical, seems ultraviolet light, blue ray radiation, is all freely
The light source of base.These free radicals can make ocular cell generate oxidation, gently then strength be caused to decline, heavy then generate macular area
Lesion, cataract, retinopathy, it is last even to have the possibility for making blindness.So the nutrition of ocular cell how is supplemented,
Increase the ability of its antioxidation, is then the project that Medical circle is being studied.
ZINC zinc is anti-oxidant-and zinc can assist anti-oxidant, and prevent the blurring of image, reduce eye illness.Body is helped to absorb dimension
Raw element A- zinc participates in the metabolism of vitamin A, and vitamin A is the important substance for safeguarding vision health.More than so how being directed to
Element design a kind of method of protection eyesight, this becomes our problems to be solved.
Invention content
The present invention is to solve above-mentioned phenomenon, using the technical solution of following modification, a method of protection eyesight, specific side
Method include it is as follows,
S1 makes the lutein ester of high-purity first；
S2 makes the brewer's yeast of high-purity；
S3 makes the zinc gluconate of high-purity；
S4 makes the oligofructose of high-purity；
S5 mixes the above zinc gluconate and oligofructose, then first pours into lutein ester and is heated, heating
Temperature is controlled at 85-120 DEG C, time control is in 45min, when being cooled to room temperature, is then slowly added into brewer's yeast, is filled
Divide and be stirred, then the 20min that simmers in water is to get finished product；
S6, raw material packaging：The finished product processed is subjected to disinfection by ultraviolet light, the good solution of sterilizing is then packed into bottle
In packing machine, by being fitted into Packaging Bottle according to fixed weight, every bottle of 15-30ml after the completion of loading, is integrally sealed place
Reason completes processing.
As present invention further optimization mode, the lutein ester entirety accounting is set as 32%, the brewer's yeast
Whole accounting be set as 14%, the whole accounting of the zinc gluconate is set as 26%, and the whole accounting of the oligofructose is set
It is 28%.
As present invention further optimization mode, the zinc gluconate makes using glucose as raw material, uses Aspergillus
Fermentation neutralizes after detaching, purifying with zinc oxide or zinc hydroxide.Also can by glucose through air oxidation, then with hydrogen-oxygen
Change sodium solution and be converted into sodium gluconate, the gluconic acid solution of high-purity is converted into through storng-acid cation exchange resin, most
It reacts and is made with zinc oxide or zinc hydroxide afterwards.
As present invention further optimization mode, the brewer's yeast production method includes the following steps,
L1 selects container and liquid：Container must be clean, sealable；Water is necessary for cold water；After wheat juice must steam boiling
It takes；
L2, the first preparation of 4-6Bx wheats juice：The 10-12Bx after boiling is taken, adds equivalent cold water, is rapidly cooled to 30-32
DEG C, it is added in sealable clean container.
L3 takes a certain amount of dry ferment to be added in the wheat juice of 4-6Bx, and wheat juice dosage is 5-10 times of dry ferment.
L4 shook two minutes every 10 minutes, activated two hours, you can pours into fermentation filling, then pumping wheat juice can start
Fermentation, ferment control fermentation initial temperature is 11 DEG C, and fermentation maximum temperature is 15 DEG C, and beer active dry yeast dosage is 0.4 ‰,
Opposite wheat juice volume, starts pressurize after 48-72 hours, pol is 15 DEG C or more in 4.5Bx or so, fermentation initial temperature at this time
When, yeast dosage is hypoglycemic to 4.5Bx or so after 0.3 ‰, 24 hours, you can pressurize, when fermentation initial temperature is 8-9 DEG C, and ferment
Female dosage is 0.5 ‰, generally takes 5-10 days hypoglycemics to 4.5Bx or so, completion is processed.
As present invention further optimization mode, the lutein ester production method includes the following steps,
A, under the conditions of 20~70 DEG C, dissolving marigold flower grain is in normal butane or acetone, stirring 0.5~5 hour, fully
Active ingredient therein is extracted, filters, obtains extracting solution；
The extracting solution obtained in step a is added adsorbent, stirs 0.5~5 hour and filter at 20~70 DEG C, received by b
Collect mother liquor；
The mother liquor obtained in step b is dried in vacuo, sloughs solvent and obtain concentrate by c, band when to remove extraction flower grain
The normal butane or acetone entered；
The concentrate obtained in step c is dissolved in isopropanol or butanol, is stirred 0.5~5 hour at 20~70 DEG C by d, is formed
Slow cooling is filtered to -10~10 DEG C after being kept for 6~18 hours after uniform solution；
E washs the filter cake that isopropanol or butanol crystallizing are obtained by filtration with lower alcohol, to remove isopropanol or butanol and be dissolved in
Antioxidant is added in the impurity of lower alcohol, the filter cake after lower alcohol washing, and re-dry removes remaining lower alcohol, finally obtains height
The lutein ester of purity.
As present invention further optimization mode, the oligofructose is to pass through β (2-1) sugar by 1~3 fructosyl
Glycosidic bond is combined the mixture of ketose, Nystose and sugarcane sugar generated etc. with the fructosyl in sucrose.
The nutrition of the product supplement ocular cell of the method for the present invention processing, increases its antioxidation, is convenient for carrying, nutrition
Deliciousness, additive-free, preservative free.
Specific implementation mode
Below in conjunction in the embodiment of the present invention, technical solution in the embodiment of the present invention is clearly and completely retouched
It states, it is clear that described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.Based on the present invention
In embodiment, every other implementation obtained by those of ordinary skill in the art without making creative efforts
Example, shall fall within the protection scope of the present invention.
The present invention provides a kind of technical solution, a method of protection eyesight, specific method include it is as follows,
S1 makes the lutein ester of high-purity first；
S2 makes the brewer's yeast of high-purity；
S3 makes the zinc gluconate of high-purity；
S4 makes the oligofructose of high-purity；
S5 mixes the above zinc gluconate and oligofructose, then first pours into lutein ester and is heated, heating
Temperature is controlled at 85-120 DEG C, time control is in 45min, when being cooled to room temperature, is then slowly added into brewer's yeast, is filled
Divide and be stirred, then the 20min that simmers in water is to get finished product；
S6, raw material packaging：The finished product processed is subjected to disinfection by ultraviolet light, the good solution of sterilizing is then packed into bottle
In packing machine, by being fitted into Packaging Bottle according to fixed weight, every bottle of 15-30ml after the completion of loading, is integrally sealed place
Reason completes processing.
The lutein ester entirety accounting is set as 32%, and the whole accounting of the brewer's yeast is set as 14%, the grape
The whole accounting of saccharic acid zinc is set as 26%, and the whole accounting of the oligofructose is set as 28%.
The zinc gluconate makes using glucose as raw material, is fermented with Aspergillus, after detaching, purifying with zinc oxide or
Zinc hydroxide neutralizes.Also can be by glucose through air oxidation, then with sodium hydroxide solution it is converted into sodium gluconate, through strong
Acid cation exchange resin is converted into the gluconic acid solution of high-purity, finally reacts and is made with zinc oxide or zinc hydroxide.
The brewer's yeast production method includes the following steps,
L1 selects container and liquid：Container must be clean, sealable；Water is necessary for cold water；After wheat juice must steam boiling
It takes；
L2, the first preparation of 4-6Bx wheats juice：The 10-12Bx after boiling is taken, adds equivalent cold water, is rapidly cooled to 30-32
DEG C, it is added in sealable clean container.
L3 takes a certain amount of dry ferment to be added in the wheat juice of 4-6Bx, and wheat juice dosage is 5-10 times of dry ferment.
L4 shook two minutes every 10 minutes, activated two hours, you can pours into fermentation filling, then pumping wheat juice can start
Fermentation, ferment control fermentation initial temperature is 11 DEG C, and fermentation maximum temperature is 15 DEG C, and beer active dry yeast dosage is 0.4 ‰,
Opposite wheat juice volume, starts pressurize after 48-72 hours, pol is 15 DEG C or more in 4.5Bx or so, fermentation initial temperature at this time
When, yeast dosage is hypoglycemic to 4.5Bx or so after 0.3 ‰, 24 hours, you can pressurize, when fermentation initial temperature is 8-9 DEG C, and ferment
Female dosage is 0.5 ‰, generally takes 5-10 days hypoglycemics to 4.5Bx or so, completion is processed.
The lutein ester production method includes the following steps,
A, under the conditions of 20~70 DEG C, dissolving marigold flower grain is in normal butane or acetone, stirring 0.5~5 hour, fully
Active ingredient therein is extracted, filters, obtains extracting solution；
The extracting solution obtained in step a is added adsorbent, stirs 0.5~5 hour and filter at 20~70 DEG C, received by b
Collect mother liquor；
The mother liquor obtained in step b is dried in vacuo, sloughs solvent and obtain concentrate by c, band when to remove extraction flower grain
The normal butane or acetone entered；
The concentrate obtained in step c is dissolved in isopropanol or butanol, is stirred 0.5~5 hour at 20~70 DEG C by d, is formed
Slow cooling is filtered to -10~10 DEG C after being kept for 6~18 hours after uniform solution；
E washs the filter cake that isopropanol or butanol crystallizing are obtained by filtration with lower alcohol, to remove isopropanol or butanol and be dissolved in
Antioxidant is added in the impurity of lower alcohol, the filter cake after lower alcohol washing, and re-dry removes remaining lower alcohol, finally obtains height
The lutein ester of purity.
The oligofructose is to be combined generation with the fructosyl in sucrose by β (2-1) glycosidic bond by 1~3 fructosyl
Ketose, Nystose and sugarcane sugar etc. mixture.
The nutrition of the product supplement ocular cell of the method for the present invention processing, increases its antioxidation, is convenient for carrying, nutrition
Deliciousness, additive-free, preservative free.
Finally it should be noted that：The foregoing is only a preferred embodiment of the present invention, is not intended to restrict the invention,
Although the present invention is described in detail referring to the foregoing embodiments, for those skilled in the art, still may be used
With technical scheme described in the above embodiments is modified or equivalent replacement of some of the technical features.
All within the spirits and principles of the present invention, any modification, equivalent replacement, improvement and so on should be included in the present invention's
Within protection domain.
Claims (6)
1. a kind of method of protection eyesight, it is characterised in that：Specific method include it is as follows,
S1 makes the lutein ester of high-purity first；
S2 makes the brewer's yeast of high-purity；
S3 makes the zinc gluconate of high-purity；
S4 makes the oligofructose of high-purity；
S5 mixes the above zinc gluconate and oligofructose, then first pours into lutein ester and is heated, computer heating control
Temperature is at 85-120 DEG C, and time control is in 45min, when being cooled to room temperature, is then slowly added into brewer's yeast, is fully stirred
Mixing is mixed, then the 20min that simmers in water is to get finished product；
S6, raw material packaging：The finished product processed is subjected to disinfection by ultraviolet light, the good solution of sterilizing is then packed into bottled packet
In installation, by being fitted into Packaging Bottle according to fixed weight, every bottle of 15-30ml after the completion of loading, is integrally sealed processing,
Complete processing.
2. a kind of method of protection eyesight according to claim 1, which is characterized in that the lutein ester entirety accounting is set
It is 32%, the whole accounting of the brewer's yeast is set as 14%, and the whole accounting of the zinc gluconate is set as 26%, described low
The whole accounting of Fructooligosaccharides is set as 28%.
3. a kind of method of protection eyesight according to claim 1, which is characterized in that the zinc gluconate makes with Portugal
Grape sugar is raw material, is fermented with Aspergillus, is neutralized with zinc oxide or zinc hydroxide after detaching, purifying.It also can be by glucose
It is converted into sodium gluconate through air oxidation, then with sodium hydroxide solution, is converted into through storng-acid cation exchange resin high-purity
The gluconic acid solution of degree is finally reacted with zinc oxide or zinc hydroxide and is made.
4. a kind of method of protection eyesight according to claim 1, which is characterized in that the brewer's yeast production method packet
Include following steps,
L1 selects container and liquid：Container must be clean, sealable；Water is necessary for cold water；Wheat juice takes after must steaming boiling
With；
L2, the first preparation of 4-6Bx wheats juice：The 10-12Bx after boiling is taken, adds equivalent cold water, is rapidly cooled to 30-32 DEG C,
It is added in sealable clean container.
L3 takes a certain amount of dry ferment to be added in the wheat juice of 4-6Bx, and wheat juice dosage is 5-10 times of dry ferment.
L4 shook two minutes every 10 minutes, activated two hours, you can it pours into fermentation filling, then pumping wheat juice can start to ferment,
Ferment control fermentation initial temperature is 11 DEG C, and fermentation maximum temperature is 15 DEG C, and beer active dry yeast dosage is 0.4 ‰, relatively
Wheat juice volume, starts pressurize after 48-72 hours, pol is in 4.5Bx or so, when fermentation initial temperature is 15 DEG C or more, ferment at this time
Female dosage is hypoglycemic to 4.5Bx or so after 0.3 ‰, 24 hours, you can pressurize, when fermentation initial temperature is 8-9 DEG C, yeast is used
Amount is 0.5 ‰, generally takes 5-10 days hypoglycemics to 4.5Bx or so, completion is processed.
5. a kind of method of protection eyesight according to claim 1, which is characterized in that the lutein ester production method packet
Include following steps,
A, under the conditions of 20~70 DEG C, dissolving marigold flower grain stirs 0.5~5 hour in normal butane or acetone, fully extracts
Active ingredient therein, filtering, obtains extracting solution；
The extracting solution obtained in step a is added adsorbent, stirs 0.5~5 hour and filter at 20~70 DEG C by b, is collected female
Liquid；
The mother liquor obtained in step b is dried in vacuo, sloughs solvent and obtain concentrate by c, is brought into when extracting flower grain to remove
Normal butane or acetone；
The concentrate obtained in step c is dissolved in isopropanol or butanol, is stirred 0.5~5 hour at 20~70 DEG C by d, is formed uniform
Slow cooling is filtered to -10~10 DEG C after being kept for 6~18 hours after solution；
E washs the filter cake that isopropanol or butanol crystallizing are obtained by filtration with lower alcohol, to remove isopropanol or butanol and be dissolved in rudimentary
Antioxidant is added in the impurity of alcohol, the filter cake after lower alcohol washing, and re-dry removes remaining lower alcohol, finally obtains high-purity
Lutein ester.
6. a kind of method of protection eyesight according to claim 1, which is characterized in that the oligofructose is by 1~3
Fructosyl is combined ketose, Nystose and the sugarcane sugar generated by β (2-1) glycosidic bond with the fructosyl in sucrose
Deng mixture.
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Application publication date: 20180828 |