CN108434521A - A kind of implantation material and preparation method thereof promoting bone wound healing - Google Patents

A kind of implantation material and preparation method thereof promoting bone wound healing Download PDF

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Publication number
CN108434521A
CN108434521A CN201810613321.7A CN201810613321A CN108434521A CN 108434521 A CN108434521 A CN 108434521A CN 201810613321 A CN201810613321 A CN 201810613321A CN 108434521 A CN108434521 A CN 108434521A
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China
Prior art keywords
fixedly connected
wall
reaction kettle
silicon rubber
fixed
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CN201810613321.7A
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Chinese (zh)
Inventor
谢美明
唐康来
袁成松
杨明宇
张洪鑫
杨志金
陶旭
周兵华
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Nanfang Hospital
First Affiliated Hospital of PLA Military Medical University
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First Affiliated Hospital of PLA Military Medical University
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Priority to CN201810613321.7A priority Critical patent/CN108434521A/en
Publication of CN108434521A publication Critical patent/CN108434521A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14Macromolecular materials
    • A61L27/18Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0006Controlling or regulating processes
    • B01J19/0013Controlling the temperature of the process
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0053Details of the reactor
    • B01J19/0066Stirrers
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/18Stationary reactors having moving elements inside
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00Materials or treatment for tissue regeneration
    • A61L2430/02Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Medicinal Chemistry (AREA)
  • Dermatology (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Materials For Medical Uses (AREA)

Abstract

The invention discloses a kind of implantation materials and preparation method thereof of promotion bone wound healing, including silicon rubber, the silicon rubber is alternately made of silicon and oxygen atom, organic group there are two usually connecting on silicon atom in the silicon rubber, the organic group includes methyl, phenyl, vinyl and trifluoro propyl, and the silicon rubber is made of silicon and organic group under conditions of high temperature.The present invention avoids opening reaction kettle cover, will not change the environment of silicon rubber synthetic reaction, can ensure the hot conditions of silicon rubber synthesis, ensure the quality of silicon rubber synthesis, improve the efficiency of silicon rubber synthesis.

Description

A kind of implantation material and preparation method thereof promoting bone wound healing
Technical field
The present invention relates to medical material tech field more particularly to a kind of implantation materials and its system promoting bone wound healing Preparation Method.
Background technology
Silicon rubber has good physical and chemical stability and physiological inertia, long-term embedding in vivo, is resistant to tissue corrosion, will not By organism metabolism, absorption and degradation, there is hydrophobicity, gas permeability, heat resistance, preferable blood and histocompatbility, Yi Jiliang Good craftsmanship, common silicon rubber are mainly made of the silica chain link containing methyl and a small amount of vinyl, and the introducing of phenyl can carry The heatproof and oil resistance of silicon rubber, silicon then can be improved in the introducing of the high- and low-temperature resistance performance of high silicon rubber, trifluoro propyl and cyano Rubber low temperature resistance is functional, generally remains to work at -55 DEG C.After introducing phenyl, reachable -73 DEG C.The heat resistance of silicon rubber Can be also very prominent, at 180 DEG C can long-term work, a little higher than 200 DEG C can also bear several weeks or longer time it is still flexible, instantaneously It is resistant to 300 DEG C or more of high temperature.The good permeability of silicon rubber, OTR oxygen transmission rate is highest in synthetic polymer, in addition, silicon Rubber also has physiological inertia, will not lead to the prominent characteristic of blood coagulation, therefore is widely used in medical field, the hot sulphur of silicon rubber point Change type, room temperature vulcanized, wherein room temperature vulcanized are divided into polycondensation reaction type and addition reaction-type.High temperature silicone rubber is mainly used for making Various silastic products are made, and room temperature silicon rubber is then used primarily as bonding agent, Embedding Material or mold.Thermal vulcanization is used Amount is maximum, and thermal vulcanization is divided into methyl silicone rubber, methyl vinyl silicone rubber, methyl vinyl phenyl silicon rubber PVMQ, other Also eyeball silicon rubber, fluorine silicone rubber etc..
Raw-silastic continuously itself is nontoxic to human body, but due to the needs of every field, we need to be to silicon rubber Glue adds compounding agent, enhances its various aspects of performance, needs to add different match in existing medical silicon rubber production process Mixture, the addition of traditional batch additives make opening react kettle cover, compounding agent are added into reaction kettle, but traditional reaction kettle is opened Mode can change silicon rubber synthetic reaction environment, influence the quality of silicon rubber, and it is relatively complicated not to react kettle cover opening procedure in addition Just, time-consuming and laborious, influence silicon rubber combined coefficient.
Invention content
The purpose of the present invention is to solve silicon rubber compounding agents in the prior art to add influence synthetic reaction environment, influences The problem of quality and silicon rubber combined coefficient of silicon rubber, and the implantation material and its system of a kind of promotion bone wound healing proposed Preparation Method.
To achieve the goals above, present invention employs following technical solutions:
A kind of implantation material and preparation method thereof promoting bone wound healing, including silicon rubber, the silicon rubber by silicon and Oxygen atom is alternately constituted, and is usually connected there are two organic group on silicon atom in the silicon rubber, the organic group include methyl, Phenyl, vinyl and trifluoro propyl, the silicon rubber are made of silicon and organic group under conditions of high temperature.
Preferably, it is described promote bone wound healing implantation material in the organic group amount of accounting for it is a little, surplus be mostly silicon and Oxygen.
A kind of preparation method promoting bone wound healing, including reaction kettle ontology, the outer wall of the reaction kettle ontology are fixed There are two " J " shape fixed blocks for connection, and the upper surface of " J " the shape fixed block offers threaded hole, and the hole wall screw thread of threaded hole It is connected with bolt, the upper surface of the reaction kettle ontology is connected with reaction kettle cover, and the outer wall of the reaction kettle cover, which is fixed, to be connected It connects there are two the first fixed block to match with " J " shape fixed block, the upper surface of the reaction kettle cover is fixedly connected with the first rotation The output end of rotating motor, first electric rotating machine passes through the upper surface of reaction kettle cover and extends downwardly, first electric rotating The output end of machine is fixedly connected with bull stick, and the bottom end of the bull stick is fixedly connected with diamond shape fixture block, the reaction kettle ontology it is interior Wall slidably connects support plate, and the both sides of the support plate are fixedly connected with sliding block, and the inner wall of the reaction kettle ontology offers The upper surface of the sliding slot to match with sliding block, the support plate offers circular hole, and the hole wall of circular hole is fixedly connected with the first rolling The inner wall of dynamic bearing, first rolling bearing is fixedly connected with stirring rod, and the top of the stirring rod is fixedly connected with connection Block, the upper surface of the link block offer the card slot to match with diamond shape fixture block, and the upper surface of the support plate is fixedly connected There are two the second electric rotating machine, the output end of two second electric rotating machines has been fixedly connected with gear, the reaction kettle sheet The inner wall of body offers fluting, and the inner wall of the fluting is fixedly connected with rack, the wheel and rack engagement, the reaction kettle The outer wall fixing sleeve of ontology is connected to the first fixed plate, and the upper surface of first fixed plate is fixedly connected with temperature regulating and controlling mechanism.
Preferably, the lower surface four corners of first fixed plate have been fixedly connected with support leg.
Preferably, the temperature regulating and controlling mechanism includes the slide rheostat being fixedly connected with the first fixed plate upper surface, institute It states slide rheostat movable block upper surface and is fixedly connected with the second rolling bearing, the inner wall of second rolling bearing is fixedly connected There are threaded rod, the bar wall of the threaded rod to be threaded with thread barrel, the outer wall of the thread barrel is fixedly connected with the second fixation Plate, second fixed plate lower surface are fixedly connected with the upper surface of the first fixed plate, and the inner wall of the reaction kettle ontology is fixed Equipped with heating tube.
Preferably, the one end of the threaded rod far from the second fixed plate is fixedly connected with moving block.
Preferably, the bar wall of the stirring rod is fixedly connected with multiple paddles.
Preferably, the outer wall fixation of the reaction kettle ontology is communicated with charge pipe, and the inner wall of the charge pipe is fixed with Two the first electrically operated valves.
Preferably, the lower surface of the reaction kettle ontology, which is fixed, is communicated with discharge nozzle, and the inner wall fixation of the discharge nozzle is set There is the second electrically operated valve.
Preferably, the upper surface of the reaction kettle cover offers through-hole, and the hole wall of through-hole is fixed with infrared thermometer.
Compared with prior art, the present invention provides a kind of implantation material and preparation method thereof of promotion bone wound healing, Has following advantageous effect:
1, the implantation material and preparation method thereof of promotion bone wound healing, by being provided with charge pipe, the first motor-driven valve Door, the first electric rotating machine and stirring rod first fill silicone rubber material when reaction kettle ontology is in silastic elastomer In reaction kettle ontology, reaction kettle cover is then covered, and fix by J-shaped fixed block and the first fixed block and bolt, then started Second electric rotating machine, the second electric rotating machine band moving gear rotate, gear along racks turn, then make support plate along sliding slot to Upper movement, makes link block be connect with bull stick, then starts the first electric rotating machine, and the first electric rotating machine drives bar rotation, bull stick Stirring rod is driven to rotate, stirring rod drives paddle rotation, then opens first electrically operated valve from charge pipe plus coordinates Agent closes the first electrically operated valve of first front opening, opens another first electrically operated valve again later later, so that compounding agent is entered anti- It answers and is sufficiently mixed with silicone rubber material in kettle ontology, which avoids opening reaction kettle cover, will not change silicon rubber synthetic reaction Environment, ensured silicon rubber synthesis quality, improve silicon rubber synthesis efficiency.
2, the implantation material and preparation method thereof of promotion bone wound healing, by be provided with heating tube, slide rheostat, Moving block and threaded rod need hot conditions when silastic elastomer, but reaction kettle internal temperature is more difficult to control, works as temperature When relatively low, moving block is rotated, moving block drives threaded rod rotation, threaded rod to drive the movable block movement of slide rheostat, Then the resistance for reducing heating tube circuit, increases heating tube heating power, ensures the hot conditions of silicon rubber synthesis, ensures silicon The quality of rubber synthesis.
It is not directed to part in the device to be the same as those in the prior art or can be realized by using the prior art, the present invention avoids Reaction kettle cover is opened, the environment of silicon rubber synthetic reaction will not be changed, can ensure the hot conditions of silicon rubber synthesis, is ensured The quality of silicon rubber synthesis, improves the efficiency of silicon rubber synthesis.
Description of the drawings
Fig. 1 is a kind of structural representation of implantation material promoting bone wound healing proposed by the present invention and preparation method thereof Figure;
Fig. 2 is a kind of structure of implantation material promoting bone wound healing proposed by the present invention and preparation method thereof part A Schematic diagram.
Fig. 3 is a kind of structure of implantation material promoting bone wound healing proposed by the present invention and preparation method thereof part B Schematic diagram.
Fig. 4 is a kind of structure of implantation material promoting bone wound healing proposed by the present invention and preparation method thereof C portion Schematic diagram.
In figure:1 reaction kettle ontology, 2 stirring rods, 3 paddles, 4 heating tubes, 5 support plates, 6 bull sticks, 7 link blocks, 8 first Rolling bearing, 9 J-shaped fixed blocks, 10 infrared thermometers, 11 first electric rotating machines, 12 reaction kettle covers, 13 charge pipes, 14 first electricity Movable valve, 15 discharge nozzles, 16 second electrically operated valves, 17 support legs, 18 first fixed plates, 19 sliding blocks, 20 sliding slots, 21 second rotations Motor, 22 gears, 23 racks, 24 first fixed blocks, 25 second rolling bearings, 26 threaded rods, 27 thread barrels, 28 second are fixed Plate, 29 moving blocks, 30 bolts, 31 slide rheostats.
Specific implementation mode
Following will be combined with the drawings in the embodiments of the present invention, and technical solution in the embodiment of the present invention carries out clear, complete Site preparation describes, it is clear that described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.
In the description of the present invention, it is to be understood that, term "upper", "lower", "front", "rear", "left", "right", "top", The orientation or positional relationship of the instructions such as "bottom", "inner", "outside" is to be based on the orientation or positional relationship shown in the drawings, merely to just In the description present invention and simplify description, do not indicate or imply the indicated device or element must have a particular orientation, with Specific azimuth configuration and operation, therefore be not considered as limiting the invention.
Referring to Fig.1-4, a kind of implantation material promoting bone wound healing, including silicon rubber, silicon rubber is by silicon and oxygen atom Alternately constitute, usually connect there are two organic group on silicon atom in silicon rubber, organic group include methyl, phenyl, vinyl and Trifluoro propyl, silicon rubber are made of silicon and organic group under conditions of high temperature, promote to have in the implantation material of bone wound healing The machine group amount of accounting for is a little, and surplus is mostly silicon and oxygen.
A kind of preparation method promoting bone wound healing, including reaction kettle ontology 1, the outer wall of reaction kettle ontology 1, which is fixed, to be connected It connects there are two " J " shape fixed block 9, the upper surface of " J " shape fixed block 9 offers threaded hole, and the hole wall threaded connection of threaded hole There are bolt 30, the upper surface of reaction kettle ontology 1 to be connected with reaction kettle cover 12, the outer wall of reaction kettle cover 12 is fixedly connected with two The upper surface of a the first fixed block 24 to match with " J " shape fixed block 9, reaction kettle cover 12 is fixedly connected with the first electric rotating machine 11, the output end of the first electric rotating machine 11 passes through the upper surface of reaction kettle cover 12 and extends downwardly, the first electric rotating machine 11 it is defeated Outlet is fixedly connected with bull stick 6, and the bottom end of bull stick 6 is fixedly connected with diamond shape fixture block, and the inner wall of reaction kettle ontology 1 slidably connects Support plate 5, the both sides of support plate 5 are fixedly connected with sliding block 19, and the inner wall of reaction kettle ontology 1 is offered to match with sliding block 19 The upper surface of sliding slot 20, support plate 5 offers circular hole, and the hole wall of circular hole is fixedly connected with the first rolling bearing 8, and first rolls The inner wall of bearing 8 is fixedly connected with stirring rod 2, and the bar wall of stirring rod 2 is fixedly connected with multiple paddles 3, and paddle 3 increases instead It answers and stirs range in kettle ontology 1, each ingredient in reaction kettle ontology 1 is made fully to merge, improve the quality of silicon rubber synthesis, stir The top for mixing bar 2 is fixedly connected with link block 7, and the upper surface of link block 7 offers the card slot to match with diamond shape fixture block, support The upper surface of plate 5 is fixedly connected there are two the second electric rotating machine 21, and the output end of two the second electric rotating machines 21 is fixedly connected with There are gear 22, the inner wall of reaction kettle ontology 1 to offer fluting, the inner wall of fluting is fixedly connected with rack 23, gear 22 and rack 23 engagements, the outer wall fixing sleeve of reaction kettle ontology 1 are connected to the first fixed plate 18, and the upper surface of the first fixed plate 18 is fixedly connected with Temperature regulating and controlling mechanism, temperature regulating and controlling mechanism include the slide rheostat 31 being fixedly connected with 18 upper surface of the first fixed plate, sliding 31 movable block upper surface of rheostat is fixedly connected with the second rolling bearing 25, and the inner wall of the second rolling bearing 25 is fixedly connected with spiral shell Rasp bar 26, the one end of threaded rod 26 far from the second fixed plate 28 are fixedly connected with moving block 29, and moving block 29 can facilitate screw thread The bar wall of the rotation of bar 26, threaded rod 26 is threaded with thread barrel 27, and the outer wall of thread barrel 27 is fixedly connected with the second fixation Plate 28,28 lower surface of the second fixed plate are fixedly connected with the upper surface of the first fixed plate 18, and the inner wall fixation of reaction kettle ontology 1 is set There is heating tube 4, which can ensure the hot conditions of silicon rubber synthesis, ensure the quality of silicon rubber synthesis, the first fixed plate 18 lower surface four corners have been fixedly connected with support leg 17, and the outer wall fixation of reaction kettle ontology 1 is communicated with charge pipe 13, feeds The inner wall of pipe 13 is fixed with two the first electrically operated valves 14, which avoids opening reaction kettle cover 12, will not change silicon rubber The environment of synthetic reaction has ensured the quality of silicon rubber synthesis, the efficiency of silicon rubber synthesis is improved, under reaction kettle ontology 1 Surface, which is fixed, is communicated with discharge nozzle 15, and the inner wall of discharge nozzle 15 is fixed with the second electrically operated valve 16, reacts the upper table of kettle cover 12 Face offers through-hole, and the hole wall of through-hole is fixed with infrared thermometer 10, and infrared thermometer 10 can monitor reaction kettle in real time Temperature in ontology 1, the first electric rotating machine 11, the first electrically operated valve 14, the second electrically operated valve 16, are slided second electric rotating machine 21 Dynamic rheostat 31 and heating tube 4 are electrically connected by controlling switch with external power supply, and it is the prior art that this, which is electrically connected mode, Details are not described herein.
In the present invention, by being provided with charge pipe 13, the first electrically operated valve 14, the first electric rotating machine 11 and stirring rod 2, when Reaction kettle ontology 1 is when silastic elastomer, first silicone rubber material filling in reaction kettle ontology 1, then covers anti- Kettle cover 12 is answered, and is fixed by J-shaped fixed block 9 and the first fixed block 24 and bolt 30, the second electric rotating machine 21 is then started, the Two electric rotating machines 21 are rotated with moving gear 22, and gear 22 is rotated along rack 23, then make support plate 5 along sliding slot 20 to moving up It is dynamic, so that link block 7 is connect with bull stick 6, then start the first electric rotating machine 11, the first electric rotating machine 11 drives bull stick 6 to rotate, and turns Bar 6 drives stirring rod 2 to rotate, and stirring rod 2 drives paddle 3 to rotate, and then opens first electrically operated valve 14 from charge pipe In 13 plus compounding agent, the first electrically operated valve 14 of the first front opening of closing later open another first electrically operated valve 14 again later, Make compounding agent enter in reaction kettle ontology 1 to be sufficiently mixed with silicone rubber material, which avoids opening reaction kettle cover 12, Bu Huigai The environment for becoming silicon rubber synthetic reaction has ensured the quality of silicon rubber synthesis, improves the efficiency of silicon rubber synthesis, passes through setting There are heating tube 4, slide rheostat 31, moving block 29 and threaded rod 26, hot conditions is needed when silastic elastomer, but anti- It answers kettle internal temperature more difficult to control, when temperature is relatively low, rotates moving block 29, moving block 29 drives threaded rod 26 to rotate, Threaded rod 26 drives the movable block movement of slide rheostat 31, then reduces the resistance of 4 circuit of heating tube, increases heating tube 4 Heating power ensures the hot conditions of silicon rubber synthesis, ensures the quality of silicon rubber synthesis.
The foregoing is only a preferred embodiment of the present invention, but scope of protection of the present invention is not limited thereto, Any one skilled in the art in the technical scope disclosed by the present invention, according to the technique and scheme of the present invention and its Inventive concept is subject to equivalent substitution or change, should be covered by the protection scope of the present invention.

Claims (10)

1. a kind of implantation material promoting bone wound healing, including silicon rubber, which is characterized in that the silicon rubber is former by silicon and oxygen Son is alternately constituted, and usually connects that there are two organic groups in the silicon rubber on silicon atom, and the organic group includes methyl, benzene Base, vinyl and trifluoro propyl, the silicon rubber are made of silicon and organic group under conditions of high temperature.
2. a kind of implantation material promoting bone wound healing according to claim 1, which is characterized in that the promotion bone wound The organic group amount of accounting for is a little in the implantation material that recovery is closed, and surplus is mostly silicon and oxygen.
3. a kind of preparation method promoting bone wound healing, including reaction kettle ontology (1), which is characterized in that the reaction kettle sheet The outer wall of body (1) is fixedly connected there are two " J " shape fixed block (9), and the upper surface of " J " the shape fixed block (9) offers screw thread Hole, and the hole wall of threaded hole is threaded with bolt (30), the upper surface of the reaction kettle ontology (1) is connected with reaction kettle It covers (12), the outer wall of the reaction kettle cover (12) is fixedly connected with that there are two the first fixed blocks for matching with " J " shape fixed block (9) (24), the upper surface of the reaction kettle cover (12) is fixedly connected with the first electric rotating machine (11), first electric rotating machine (11) Output end pass through the upper surface of reaction kettle cover (12) and extend downwardly, the output end of first electric rotating machine (11), which is fixed, to be connected It is connected to bull stick (6), the bottom end of the bull stick (6) is fixedly connected with diamond shape fixture block, and the inner wall sliding of the reaction kettle ontology (1) connects It is connected to support plate (5), the both sides of the support plate (5) are fixedly connected with sliding block (19), and the inner wall of the reaction kettle ontology (1) is opened Equipped with the sliding slot (20) to match with sliding block (19), the upper surface of the support plate (5) offers circular hole, and the hole wall of circular hole is solid Surely it is connected with the first rolling bearing (8), the inner wall of first rolling bearing (8) is fixedly connected with stirring rod (2), the stirring The top of bar (2) is fixedly connected with link block (7), and the upper surface of the link block (7) is offered to match with diamond shape fixture block Card slot, the upper surface of the support plate (5) are fixedly connected with that there are two the second electric rotating machine (21), two second electric rotating machines (21) output end has been fixedly connected with gear (22), and the inner wall of the reaction kettle ontology (1) offers fluting, the fluting Inner wall is fixedly connected with rack (23), and the gear (22) is engaged with rack (23), and the outer wall of the reaction kettle ontology (1) is fixed It is socketed with the first fixed plate (18), the upper surface of first fixed plate (18) is fixedly connected with temperature regulating and controlling mechanism.
4. a kind of preparation method promoting bone wound healing according to claim 3, which is characterized in that described first fixes The lower surface four corners of plate (18) have been fixedly connected with support leg (17).
5. a kind of preparation method promoting bone wound healing according to claim 3, which is characterized in that the temperature regulation and control Mechanism includes the slide rheostat (31) being fixedly connected with the first fixed plate (18) upper surface, and the slide rheostat (31) is mobile Block upper surface is fixedly connected with the second rolling bearing (25), and the inner wall of second rolling bearing (25) is fixedly connected with threaded rod (26), the bar wall of the threaded rod (26) is threaded with thread barrel (27), and the outer wall of the thread barrel (27) is fixedly connected with Second fixed plate (28), the second fixed plate (28) lower surface is fixedly connected with the upper surface of the first fixed plate (18), described The inner wall of reaction kettle ontology (1) is fixed with heating tube (4).
6. a kind of preparation method promoting bone wound healing according to claim 5, which is characterized in that the threaded rod (26) one end far from the second fixed plate (28) is fixedly connected with moving block (29).
7. a kind of preparation method promoting bone wound healing according to claim 3, which is characterized in that the stirring rod (2) bar wall is fixedly connected with multiple paddles (3).
8. a kind of preparation method promoting bone wound healing according to claim 3, which is characterized in that the reaction kettle sheet The outer wall fixation of body (1) is communicated with charge pipe (13), and the inner wall of the charge pipe (13) is fixed with two the first electrically operated valves (14)。
9. a kind of preparation method promoting bone wound healing according to claim 3, which is characterized in that the reaction kettle sheet The lower surface of body (1) is fixed and is communicated with discharge nozzle (15), and the inner wall of the discharge nozzle (15) is fixed with the second electrically operated valve (16)。
10. a kind of preparation method promoting bone wound healing according to claim 3, which is characterized in that the reaction kettle The upper surface of lid (12) offers through-hole, and the hole wall of through-hole is fixed with infrared thermometer (10).
CN201810613321.7A 2018-06-14 2018-06-14 A kind of implantation material and preparation method thereof promoting bone wound healing Pending CN108434521A (en)

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CN104474592A (en) * 2014-12-09 2015-04-01 西安科技大学 Medical organosilicone material for pancreas and intestine anastomosis instrument and preparation method thereof
CN204522970U (en) * 2015-03-17 2015-08-05 李梓齐 A kind of chemical industry stirring reaction device

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102363050A (en) * 2011-06-29 2012-02-29 大连林桥科技有限公司 Medical biological material and preparation method thereof
CN104474592A (en) * 2014-12-09 2015-04-01 西安科技大学 Medical organosilicone material for pancreas and intestine anastomosis instrument and preparation method thereof
CN204522970U (en) * 2015-03-17 2015-08-05 李梓齐 A kind of chemical industry stirring reaction device

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Title
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