CN108434341A - A kind of Chinese medicine preparation and preparation method for treating atrophic gastritis navel patch - Google Patents

A kind of Chinese medicine preparation and preparation method for treating atrophic gastritis navel patch Download PDF

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CN108434341A
CN108434341A CN201810664675.4A CN201810664675A CN108434341A CN 108434341 A CN108434341 A CN 108434341A CN 201810664675 A CN201810664675 A CN 201810664675A CN 108434341 A CN108434341 A CN 108434341A
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parts
root
chinese medicine
atrophic gastritis
preparation
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石国剑
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Jiangsu Hundred Sword Pharmaceutical Technology Co Ltd
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Jiangsu Hundred Sword Pharmaceutical Technology Co Ltd
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
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Abstract

The present invention provides the present invention relates to a kind of Chinese medicine preparations and preparation method thereof for treating atrophic gastritis navel patch, the Chinese medicine preparation includes the stem of noble dendrobium, perfume Citron skins, root of Aucklandia lappa Decne, agalloch eaglewood, basic fuchsin, Hericium erinaceus, pig gall bladder, Divine Comedy, Endothelium Corneum Gigeriae Galli (parched), the root of three-nerved spicebush, grass-leaved sweetflag, the root of straight ladybell, Radix Ophiopogonis.Navel of the present invention patch provides that a kind of one kind for treating atrophic gastritis in addition to endo-medicine other than is outer to control mode, with convenient, effective, uneasy to recur advantage.

Description

A kind of Chinese medicine preparation and preparation method for treating atrophic gastritis navel patch
Technical field
The present invention relates to a kind of Chinese medicine preparation, especially a kind of Chinese medicine preparation for treating atrophic gastritis navel patch and preparation side Method.
Background technology
Atrophic gastritis is also referred to as atrophic gastritis, and with gastric epithelial and body of gland atrophy, number is reduced, and stomach lining becomes Thin, mucous membrane base thickens, or with gland metaplasia and intestinal gland metaplasia, or the chronic digestible system disease for having atypical hyperplasia to be characterized Disease.Upper abdomen secret anguish, turgor, belch often are shown as, is lost the appetite, or is become thin, anaemia etc., no specificity.It is a kind of mostly pathogenic Because of disposition disease and precancerous lesion.Western medical treatment atrophic gastritis does not have particularly effective drug at present, just for disease Some medicines of shape.It is mostly oral that Chinese medicine, which treats this disease,.
Invention content
For the drug for being applicable to treatment atrophic gastritis for obtaining new and effective, the present inventor is to this by a large amount of deep Enter research, after having paid sufficient creative work, so as to complete the present invention.
The present invention relates to a kind of Chinese medicine preparation for treating atrophic gastritis, the Chinese medicine preparation includes 17-20 parts of the stem of noble dendrobium, perfume 12-15 parts of Citron skins, 7-10 parts of root of Aucklandia lappa Decne, 2-5 parts of agalloch eaglewood, 5-8 parts of basic fuchsin, 6-9 parts of Hericium erinaceus, 3-6 parts of pig gall bladder, Divine Comedy 7-10 Part, 6-9 parts of the root of three-nerved spicebush of 7-10g parts of Endothelium Corneum Gigeriae Galli (parched), 6-9 parts of grass-leaved sweetflag, 6-9 parts of the root of straight ladybell, Radix Ophiopogonis 6-9 part.
Property enumerates as an example, and in described pharmaceutical composition, in parts by weight, concrete component content is as follows：
20 parts of the stem of noble dendrobium, 12 parts of perfume Citron skins, 10 parts of root of Aucklandia lappa Decne, 2 parts of agalloch eaglewood, 5 parts of basic fuchsin, 6 parts of Hericium erinaceus, 6 parts of pig gall bladder, god 10 parts bent, 10 parts of Endothelium Corneum Gigeriae Galli (parched), 6 parts of the root of three-nerved spicebush, 6 parts of grass-leaved sweetflag, 6 parts of the root of straight ladybell, 6 parts of Radix Ophiopogonis.
If above-mentioned navel pastes, preparation method is：1) Pericarpium Citri, root of Aucklandia lappa Decne, agalloch eaglewood extraction volatilization are weighed by above-mentioned parts by weight Oil；2) other all kinds of medicinal materials are weighed according to above-mentioned parts by weight to be uniformly mixed, the water tanning of 10 times of volumes is added, changes small fire after boiling It boils medicine again 20 minutes, the traditional Chinese medicine liquid of tanning is poured into container, the water that active compound slag adds 10 times of volumes repeats to boil medicine one time, The dregs of a decoction are outwelled, the traditional Chinese medicine liquid boiled twice is mixed into and is evaporated together, extra moisture evaporation is fallen, are obtained as in pasta Medicine preparation；3) volatile oil, a certain amount of penetrating agent and the moisturizer of step 1) extraction are added into above-mentioned paste Chinese medicine preparation, applies Onto non-woven fabrics, it is prepared into navel patch.
The penetrating agent can be peppermint oil, lemon oil, eucalyptus oil, caryophyllus oil, selinum oil, Chinese angelica volatile oil, turpentine oil etc..
The moisturizer can be glycerine, vaseline, beeswax etc..
Navel patch as described above, application method are：Be applied with navel treatment, every time patch 24 hours, the next day it is primary.
Advantageous effect：Navel patch is external preparation, and navel is SHENQUE acupoint, this cave is the center of body surface gravitational field, right Appearance substance in human body has the place that powerful spasm acts on and stomach wall is most thin, acupuncture point to have warming and tonifying primordial YANG, is good for fortune spleen The benefits of stomach, recovery prevent prolapse.Above-mentioned navel pastes Chinese medicine preparation multiselect promoting qi circulation and relieving pain, and the Chinese medicine of strengthening the spleen and stomach proves all in clinic It is that there is apparent therapeutic effect to atrophic gastritis.There are some Chinese medicines that there is volatility in this prescription, while adding some tools There is volatile Chinese medicine to increase the transmitance to stomach wall, improves curative effect.Navel of the present invention patch provide it is a kind of in addition to The outer of atrophic gastritis is treated other than endo-medicine controls mode.With convenient, fast, effective advantage.It is of the present invention Navel patch can be used alone and can be also used cooperatively with existing endo-medicine, improve therapeutic efficiency.
The pharmacological property of main component：
1), the stem of noble dendrobium：Meridian distribution of property and flavor：It is slightly cold；It is sweet；Return stomach, kidney channel
Major function：Reinforcing stomach reg fluid, nourishing Yin and clearing heat.For impairment of yin body fluid deficiency, dry polydipsia, deficiency of food is retched, after being ill abnormal heat, mesh It is dark unknown.
The stem of noble dendrobium has excitation to intestinal tube, shrinkage amplitude can be made to increase.Pharmacological testing shows that oral stem of noble dendrobium decoction can promote Gastric secretion helps digest.Dendrobine is similar to Fei Xiting drug effects and effect is weaker, and stem of noble dendrobium medicinal extract can stimulate intestinal smooth muscle It shrinks, promotes gastrointestinal peristalsis.The stem of noble dendrobium can receive atrophic gastritis unique, satisfied effect.In addition, the stem of noble dendrobium contains esters Ingredient has the function of promoting blood circulation and removing blood stasis, expansion blood vessel and antiplatelet condensation, can improve the blood circulation of gastric tissue.
2) Pericarpium Citri：
Meridian distribution of property and flavor：It is pungent, sour, it is nontoxic.
Major function：Lower gas, removes phlegm water, gas pain under the heart.This product be stomach invigorating purging medicine, for indigestion, abundant expectoration uncomfortable in chest, The diseases such as vomiting；For chronic gastritis, nerve stomachache (peratodynia) is more suitable.
This product is containing citric acid, vitamin (C, P), hesperidine, citric acid, malic acid, pectin, tannin.To chronic gastritis, god It is preferable through property stomachache curative effect.Contained volatile oil has mild stimulation to gastrointestinal tract, can promote to wriggle in stomach and digestive juice divides It secretes, excludes enteral pneumatosis, and have phlegm-dispelling functions.
3) root of Aucklandia lappa Decne：
Meridian distribution of property and flavor：It is pungent, bitter, temperature.Returns spleen, stomach, large intestine, three burnt, gallbladder channels
Function with cure mainly：Promoting qi circulation and relieving pain, that qi-regulating is soothing the liver, invigorating the spleen disappears is stagnant.
This product pungent-warm perfume (or spice) dissipates, and can rise can drop, and leads to the gas of three cokes of reason, the especially gas of benefaction stomach and intestine and relieves pain, has invigorating the spleen concurrently and disappear The work(of food, all cards caused by all taste qi stagnation of large intestines are common product.4) agalloch eaglewood：
Meridian distribution of property and flavor：It is pungent, bitter, temperature.Returns spleen, stomach, kidney, lung channel
Effect：It is supporing yang to warm up kidney for sending down abnormally ascending middle benefit gas.
It cures mainly：It controls the circulation of vital energy in the wrong direction to pant, vomits hiccup, abdominal distention, waist and knee void is cold,
Large intestine void is secret, the leaching of urine gas, man's cold sperm.
Root of Aucklandia lappa Decne is used cooperatively with agalloch eaglewood, has the function of tonifying Qi promoting the circulation of qi.
Specific implementation mode
Below by specific embodiment, the present invention is described in detail, but the purposes of these exemplary embodiments and Purpose is only used for enumerating the present invention, not constitutes any type of any restriction to the real protection scope of the present invention, more non-to incite somebody to action Protection scope of the present invention is confined to this.
Embodiment 1
A kind of Chinese medicine preparation for treating atrophic gastritis, by following components parts by weights array at (every part of 1g)
17 parts of the stem of noble dendrobium, 12 parts of perfume Citron skins, 7 parts of root of Aucklandia lappa Decne, 2 parts of agalloch eaglewood, 5 parts of basic fuchsin, 6 parts of Hericium erinaceus, 3 parts of pig gall bladder, god 7 parts bent, 7 parts of Endothelium Corneum Gigeriae Galli (parched), 6 parts of the root of three-nerved spicebush, 6 parts of grass-leaved sweetflag, 6 parts of the root of straight ladybell, 6 parts of Radix Ophiopogonis.
Specific preparation method is as follows：
1) Pericarpium Citri, root of Aucklandia lappa Decne, agalloch eaglewood are weighed by above-mentioned parts by weight and extracts volatile oil；2) it is weighed according to above-mentioned parts by weight other All kinds of medicinal materials are uniformly mixed, and the water tanning of 10 times of volumes is added, changes small fire after boiling and boils medicine again 20 minutes, by the Chinese medicine medicine of tanning Liquid pours into container, and the water that active compound slag adds 10 times of volumes repeats to boil medicine one time, the dregs of a decoction is outwelled, the Chinese medicine that will be boiled twice Liquid is mixed into be evaporated together, and extra moisture evaporation is fallen, and is obtained as pasta Chinese medicine preparation；3) to above-mentioned paste Chinese medicine preparation Middle volatile oil, a certain amount of penetrating agent and the moisturizer that step 1) extraction is added, is coated onto on non-woven fabrics, is prepared into navel patch.
Be applied with navel treatment, every time patch 24 hours, the next day it is primary.
Embodiment 2
A kind of Chinese medicine preparation for treating atrophic gastritis, by following components parts by weights array at (every part of 1g)
20 parts of the stem of noble dendrobium, 15 parts of perfume Citron skins, 10 parts of root of Aucklandia lappa Decne, 5 parts of agalloch eaglewood, 8 parts of basic fuchsin, 9 parts of Hericium erinaceus, 6 parts of pig gall bladder, god 10 parts bent, 9 parts of the root of three-nerved spicebush of 10g parts of Endothelium Corneum Gigeriae Galli (parched), 9 parts of grass-leaved sweetflag, 9 parts of the root of straight ladybell, 9 parts of Radix Ophiopogonis.
Specific preparation method and application method are the same as embodiment 1.
Embodiment 3
A kind of Chinese medicine preparation for treating atrophic gastritis, by following components parts by weights array at (every part of 1g)
20 parts of the stem of noble dendrobium, 12 parts of perfume Citron skins, 10 parts of root of Aucklandia lappa Decne, 2 parts of agalloch eaglewood, 5 parts of basic fuchsin, 6 parts of Hericium erinaceus, 6 parts of pig gall bladder, god 10 parts bent, 10 parts of Endothelium Corneum Gigeriae Galli (parched), 6 parts of the root of three-nerved spicebush, 6 parts of grass-leaved sweetflag, 6 parts of the root of straight ladybell, 6 parts of Radix Ophiopogonis.
Specific preparation method and application method are the same as embodiment 1.
Performance test：
Therapeutic efficiency of the navel patch of the present invention to atrophic gastritis.
Subjects：200, suffer from atrophic gastritis.
Test method：
200 patients are randomly divided into two groups, i.e. 100 people of oral medicine group, age 30-70 Sui, the course of disease -2 years 6 months；Navel 100 people of patch group, age 28-68 Sui, the course of disease -2 years 7 months.
Brief summary：Symptom improves situation and compares.2 groups of patient's abdominal pain, abdominal distension, loss of appetite all improve significantly, but control Recurrence rate navel patch group after treatment is significantly lower than oral medicine group (being shown in Table 1).
12 groups of patients with atrophic gastritis symptoms of table improve situation and compare [example (%)]
Case and clinical effectiveness：
Clinical application and effect of the Chinese medicine preparation of the present invention in treating atrophic gastritis.
1) Mrs Liu 55 years old, suffers from atrophic gastritis 3 years, when have stomach pain, do not feel like eating abdominal distension, belch acid regurgitation is angry Pain aggravates afterwards, dry and hard excrement, dark urine, red tongue body, and the navel patch that moss thin yellow is prepared using Chinese medicine preparation of the present invention is controlled After treating March, stomach pain is relieved, and appetite increases.Analysis：Such patient is of the present invention because fire caused by depression of liver-QI violates stomach Navel patch prepared by Chinese medicine preparation has the effect of soothing liver-qi stagnation, regulating qi-flowing for relieving pain, reaches therapeutic effect.
2) Mrs Li 43 years old, suffers from atrophic gastritis 2 years.Patient for many years when there is the gastral cavity pain, mostly shouting pain, pain to be in Paroxysmal, pain very then reflexes to the shoulder back of the body, thirsty, receives difference, and stool is dry, and urine is yellow, and tongue is dark red, and there are ecchymosis, moss thin yellow, arteries and veins in tongue side It is puckery.After the navel patch treatment prepared using Chinese medicine preparation of the present invention 3 months, pain of gastric cavity is substantially reduced after medication, without thirsty, two Just normal, patient symptom disappears, clinical cure.Parsing：Such patient because the stagnation of the circulation of vital energy with the passing of time due to cause blood stasis, Chinese medicine of the present invention is matched There is the navel patch just prepared the promoting flow of qi and blood circulation to reach therapeutic effect the effect of removing obstruction in channels to relieve pain.
3) Mr. Liu, 48 years old.Suffer from atrophic gastritis 2 years, when there is stomach to have a dull ache, have noisy sense in stomach.With dry tongue Dry, hidrosis, especially night sweat is more, irritated, becomes thin, after navel prepared by weak Chinese medicine preparation of the present invention pastes 3 months, patient's stomach Portion's pain and noisy sense disappear, no thirsty, perspire and weak sense mitigates, weight gain.Parsing：For such stomach-Yin deficiency disease There is enriching yin invigorating the spleen, the effect of nourishing the stomach in reach therapeutic effect for disease, navel patch prepared by Chinese medicine preparation of the present invention.
To sum up, there is navel patch of the present invention lasting medicine, the low advantage of recurrence rate can make together with oral drugs With improving the efficiency for the treatment of.
It should be appreciated that the purposes of these embodiments is merely to illustrate the present invention and is not intended to limitation protection model of the invention It encloses.In addition, it should also be understood that, after reading the technical contents of the present invention, those skilled in the art can make the present invention each Kind change, modification and/or variation, all these equivalent forms equally fall within and are protected defined by the application the appended claims Within the scope of shield.

Claims (1)

1. a kind of Chinese medicine for treating atrophic gastritis, it is characterised in that：In parts by weight, concrete component content is as follows：
20 parts of the stem of noble dendrobium, 12 parts of perfume Citron skins, 10 parts of root of Aucklandia lappa Decne, 2 parts of agalloch eaglewood, 5 parts of basic fuchsin, 6 parts of Hericium erinaceus, 6 parts of pig gall bladder, Divine Comedy 10 Part, 10 parts of Endothelium Corneum Gigeriae Galli (parched), 6 parts of the root of three-nerved spicebush, 6 parts of grass-leaved sweetflag, 6 parts of the root of straight ladybell, 6 parts of Radix Ophiopogonis.
CN201810664675.4A 2018-06-25 2018-06-25 A kind of Chinese medicine preparation and preparation method for treating atrophic gastritis navel patch Withdrawn CN108434341A (en)

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