CN108434331A - A kind of Chinese medicine composition and preparation method thereof for treating enruesis - Google Patents
A kind of Chinese medicine composition and preparation method thereof for treating enruesis Download PDFInfo
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- CN108434331A CN108434331A CN201810455014.0A CN201810455014A CN108434331A CN 108434331 A CN108434331 A CN 108434331A CN 201810455014 A CN201810455014 A CN 201810455014A CN 108434331 A CN108434331 A CN 108434331A
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- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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Abstract
The invention discloses a kind of Chinese medicine compositions for treating enruesis, include the component of following parts by weight:2~4 parts of ginseng, 9~11 parts of Radix Astragali, 11~13 parts of Gorgon fruit, 5~7 parts of the fruit of Cherokee rose, 4~6 parts of psoralea corylifolia, 8~10 parts of Semen Cuscutae, 8~10 parts of Chinese yam, 8~10 parts of grass-leaved sweetflag, 1~3 part of pilose antler, 4~6 parts of Chinese ephedra, 1~3 part of evodia rutaecarpa, 0.5~1.5 part of the root of Dahurain angelica, 0.5~1.5 part of white pepper, 3~5 parts of honeycomb, 3~5 parts of hawthorn, 3~5 parts of Chinese yam, 3~5 parts of the membrane of a chicken's gizzard, 18~22 parts of the bletilla striata.The invention belongs to technical field of traditional Chinese medicines to achieve the purpose that safely and effectively to treat enruesis, curative effect of the present invention is stablized, and has no toxic side effect, uneasy to recur after drug withdrawal by selecting suitable natural Chinese traditional medicines material and its proportioning.
Description
Technical field
The invention belongs to technical field of traditional Chinese medicines, in particular to a kind of Chinese medicine composition for treating enruesis and its preparation sides
Method.
Background technology
Enruesis is commonly called as wetting the bed, and is often referred to 3 years old or more especially 5 years old or more children and is unable to automatic micturition when sleeping soundly, and one
As 3~4 years old when there are 20% children to have an enruesis, 10 years old when, has 5% children to have enruesis, there is small number of patients enuresis symptoms last
To the manhood.The characteristics of enuresis is:There is no apparent urinary tract neurological organic disease.Enuresis
Number of the infected is higher, accounts for about the 70~80% of enruesis total number of persons.Infantile enuresis is such as not treated in time, and so that child is formed interior
To, sensitive, timid, inferiority complex, Character Limitation is caused, and child's growth can be influenced, partially short, partially thin or puffiness type body occurs
Material.Enuresis time length is also possible to lead to child's poor memory, and absent minded, school grade is poor, and then influences child's adult
Interpersonal relationships afterwards, career development and family harmony.From clinical nearly 30 years case summaries, enruesis to patient especially not
The body of adult patients, psychological harm are big and lasting.
Treatment enruesis, the drug of the urinary incontinence are numerous both at home and abroad at present, but curative effect is undesirable, traces it to its cause:Drug is more
For Western medicine, and it is mostly nervous stimulants, toxic side effect is big, and curative effect is unstable, is easily recurred after drug withdrawal.Common maincenter god
Through excitant:Such as imipramine, pro-banthine or amitriptyline, enter per os hora somni, detrusor can be made to relax, and bladder is inhibited to receive
Contracting controls the enuresis.But these medicine side effects are big, and effect is only 30~40%, is easily recurred after drug withdrawal.The enuresis is thought on tcm clinical practice
The pathogenesis of disease is:For patient because native endowment is insufficient or ferritic weakness leads to deficiency of kidney-QI, below element deficiency and cold cannot the foster wing of temperature
Guang, functioning of bladder functional disturbance close Tibetan dereliction of duty, cannot keep within bounds water channel, and are the enuresis.When asthenia of pulmonosplenic qi, when dampness-heat of liver channel, upper void
Cannot make down, lower void cannot on hold, cause to have no right to constrain water channel, then incontinence of urine, or sleep middle urine from going out, can also cause to lose
Urine.And the teenage patient of the disease is in the majority, so the present invention is in nearly clinical research in 30 years, more than 10 ten thousand rehabilitations
It is special to be developed by foothold of traditional Chinese medicine during curative effect is summarized.
Invention content
To solve above-mentioned existing problem, the present invention prepares one by selecting suitable natural Chinese traditional medicines material and its proportioning
Kind treats the Chinese medicine composition of enruesis, achievees the purpose that safely and effectively to treat enruesis, and curative effect of the present invention is stablized, nontoxic secondary work
With uneasy to recur after drug withdrawal.
The technical solution adopted by the present invention is as follows:A kind of Chinese medicine composition for treating enruesis, including following parts by weight
Component:2~4 parts of ginseng, 9~11 parts of Radix Astragali, 11~13 parts of Gorgon fruit, 5~7 parts of the fruit of Cherokee rose, 4~6 parts of psoralea corylifolia, Semen Cuscutae 8~
10 parts, 8~10 parts of Chinese yam, 8~10 parts of grass-leaved sweetflag, 1~3 part of pilose antler, 4~6 parts of Chinese ephedra, 1~3 part of evodia rutaecarpa, the root of Dahurain angelica 0.5~
1.5 parts, 0.5~1.5 part of white pepper, 3~5 parts of honeycomb, 3~5 parts of hawthorn, 3~5 parts of Chinese yam, 3~5 parts of the membrane of a chicken's gizzard, the bletilla striata 18~
22 parts.
Further, a kind of Chinese medicine composition for treating enruesis, includes the component of following parts by weight:3 parts of ginseng, Radix Astragali
10 parts, 12 parts of Gorgon fruit, 6 parts of the fruit of Cherokee rose, 5 parts of psoralea corylifolia, 9 parts of Semen Cuscutae, 9 parts of Chinese yam, 9 parts of grass-leaved sweetflag, 2 parts of pilose antler, Chinese ephedra 5
Part, 2 parts of evodia rutaecarpa, 1 part of the root of Dahurain angelica, 1 part of white pepper, 4 parts of honeycomb, 4 parts of hawthorn, 4 parts of Chinese yam, 4 parts of the membrane of a chicken's gizzard, 20 parts of the bletilla striata.
Further, a kind of Chinese medicine composition for treating enruesis further includes the component of following parts by weight:20 parts of the bletilla striata,
10 parts of grass-leaved sweetflag, 10 parts of psoralea corylifolia, 50 parts of Radix Astragali, for steeping foot medicine after said components are milled.
The invention also discloses a kind of preparation methods of Chinese medicine composition that treating enruesis, include the following steps:
1) each component is weighed according to the weight part ratio of component;
2) pilose antler is burned into pilose antler fine hair with no pyrotechnics, is shaved with bamboo knife, the broken ends of fractured bone of pilose antler is immersed in 0.5 in 50 DEG C of hot wine
It~l hours, is sliced after pilose antler softening, it is spare to be ground into pilose antler powder;By ginseng, Radix Astragali, Gorgon fruit, the fruit of Cherokee rose, psoralea corylifolia, Tu
Son, Chinese yam, grass-leaved sweetflag, Chinese ephedra, merging vessel are interior to add cold water soak half an hour, the water of 8 times of medicine weight is added, after being boiled by fire
It is 20 minutes pan-fried to change small fire, concoction is filtered out, the water of 6 times of medicine weight is added, it is multiple to decoct once, concoction twice is poured in obtaining together
Medicine decoction, while taking the pilose antler powder of parts by weight developed to be added in the traditional Chinese herbal decoction of tanning and obtaining oral decoction;
3) evodia rutaecarpa of parts by weight, the root of Dahurain angelica, white pepper mixed in proportion, smashed, being ground up, sieved into herb powder, added
With appropriate light-coloured vinegar to paste is tuned into, navel medicine for external application is obtained;
4) honeycomb of parts by weight is put in iron pan and is slowly heated, until fine grinding while hot when crisp, by the mountain of parts by weight
Powder one is made in short, bristly hair or beard, Chinese yam, the membrane of a chicken's gizzard jointly, and powder one and the honeycomb powder of parts by weight obtain dietotherapy medicinal powder after mixing.
Further, the oral decoction described in step 2) is divided into two parts, respectively takes portion sooner or later.
Further, the navel medicine for external application described in step 3) spreads on umbilical region, sticks every night, and m seq is removed, and daily one
It is secondary.Evodia rutaecarpa, the root of Dahurain angelica take the effect of its middle benefit gas, qi-regulating, eliminating dampness in we;The effect of white pepper takes its warming spleen and stomach for dispelling cold, lower gas.
Further, the dietotherapy medicinal powder described in step 4) respectively takes 4g daily morning and evening, can be mixed into white sugar boiling water take after mixing it with water or
It can be mixed into congee and take.
The Chinese medicine composition that the present invention treats enruesis includes oral decoction, navel medicine for external application, steeps foot medicine and dietotherapy medicine,
The bubble foot medicine principle and necessity of middle navel medicine for external application and vola bubble foot are as follows:The navel of navel medicine for external application is treated to be administered by navel
It excites QI of channels and collaterals, the promoting flow of qi and blood, conditioning viscera to coordinate oral decoction during treating enruesis, solves patient's inconvenience
Puzzlement or malabsorption problem.It is mostly kidney that the principle and necessity of the bubble foot medicine of vola bubble foot, which are the enuresis thought based on Chinese medicine,
Unsaturated vapor, treating deficient cold caused by spleen and lung deficiency, are controlled and preferably train first kidney tonifying, strengthening spleen and tonifying lung, footbath with traditional Chinese medicines is the outer side of controlling of tcm characteristic
One of method is to achieve the purpose that treat enruesis by the therapeutic effect of the physical and chemical effect and drug of water, promotes medicine using hot water
Object permeates human body, expands the capillary of foot, and the effective ingredient of Chinese medicine is made adequately to be passed through by capillary circulation to whole body
Network, to have the function that the first kidney tonifying of training, strengthening spleen and tonifying lung, footbath with traditional Chinese medicines can guarantee that drug can be reached the whole body thoroughly by foot and be passed through
Network.
The enruesis course of disease is longer, recurrent exerbation, and severe cases daytime sleepiness can also occur, and the big Age Variations of enuresis sufferers
It is smaller, it is difficult to adhere to taking, dietotherapy prescription agent of arranging in pairs or groups can both heighten the effect of a treatment, and the patient that can be also directed to inconvenient medication controls
It treats.
The present invention is obtained and is had the beneficial effect that using the above scheme:The present invention treats the selected conjunction of Chinese medicine composition of enruesis
Suitable natural Chinese traditional medicines material and its proportioning cooperate between each component, act synergistically, can warm kidney benefit spleen, astringent method only lose, energy
Enough effectively treatment enruesises, and it is of low cost, preparation process is simple, quick, curative for effect, and pharmacological property is mild, secondary without any poison
Effect is particularly suitable for the old and the weak children's sufferer and uses.It is provided by the invention treatment enruesis Chinese medicine composition carry and it is easy to use,
It to human body significant effect, is verified through clinical test, effective percentage is not less than 93%.
Specific implementation mode
The technical scheme in the embodiments of the invention will be clearly and completely described below, it is clear that described implementation
Example is only a part of the embodiment of the present invention, instead of all the embodiments.Based on the embodiments of the present invention, this field is common
All other embodiment that technical staff is obtained without making creative work belongs to the model that the present invention protects
It encloses.
Embodiment 1, the present invention treat the Chinese medicine composition of enruesis, include the component of following parts by weight:3 parts of ginseng, Huang
10 parts of stilbene, 12 parts of Gorgon fruit, 6 parts of the fruit of Cherokee rose, 5 parts of psoralea corylifolia, 9 parts of Semen Cuscutae, 9 parts of Chinese yam, 9 parts of grass-leaved sweetflag, 2 parts of pilose antler, Chinese ephedra 5
Part, 2 parts of evodia rutaecarpa, 1 part of the root of Dahurain angelica, 1 part of white pepper, 4 parts of honeycomb, 4 parts of hawthorn, 4 parts of Chinese yam, 4 parts of the membrane of a chicken's gizzard, 20 parts of the bletilla striata.
The present invention treats the preparation method of the Chinese medicine composition of enruesis, includes the following steps:
1) each component is weighed according to the weight part ratio of component;
2) pilose antler is burned into pilose antler fine hair with no pyrotechnics, is shaved with bamboo knife, the broken ends of fractured bone of pilose antler is immersed in 0.5 in 50 DEG C of hot wine
It~l hours, is sliced after pilose antler softening, it is spare to be ground into pilose antler powder;By ginseng, Radix Astragali, Gorgon fruit, the fruit of Cherokee rose, psoralea corylifolia, Tu
Son, Chinese yam, grass-leaved sweetflag, Chinese ephedra, merging vessel are interior to add cold water soak half an hour, the water of 8 times of medicine weight is added, after being boiled by fire
It is 20 minutes pan-fried to change small fire, concoction is filtered out, the water of 6 times of medicine weight is added, it is multiple to decoct once, concoction twice is poured in obtaining together
Medicine decoction, while taking the pilose antler powder of parts by weight developed to be added in the traditional Chinese herbal decoction of tanning and obtaining oral decoction;
3) evodia rutaecarpa of parts by weight, the root of Dahurain angelica, white pepper mixed in proportion, smashed, being ground up, sieved into herb powder, added
With appropriate light-coloured vinegar to paste is tuned into, navel medicine for external application is obtained;
4) honeycomb of parts by weight is put in iron pan and is slowly heated, until fine grinding while hot when crisp, by the mountain of parts by weight
Powder one is made in short, bristly hair or beard, Chinese yam, the membrane of a chicken's gizzard jointly, and powder one and the honeycomb powder of parts by weight obtain dietotherapy medicinal powder after mixing.
Embodiment 2, the present invention treat the Chinese medicine composition of enruesis, include the component of following parts by weight:4 parts of ginseng, Huang
11 parts of stilbene, 13 parts of Gorgon fruit, 7 parts of the fruit of Cherokee rose, 6 parts of psoralea corylifolia, 10 parts of Semen Cuscutae, 10 parts of Chinese yam, 10 parts of grass-leaved sweetflag, 3 parts of pilose antler, fiber crops
6 parts yellow, 3 parts of evodia rutaecarpa, 1.5 parts of the root of Dahurain angelica, 1.5 parts of white pepper, 5 parts of honeycomb, 5 parts of hawthorn, 5 parts of Chinese yam, 5 parts of the membrane of a chicken's gizzard, the bletilla striata
22 parts.
The present invention treats the preparation method of the Chinese medicine composition of enruesis, includes the following steps:
1) each component is weighed according to the weight part ratio of component;
2) pilose antler is burned into pilose antler fine hair with no pyrotechnics, is shaved with bamboo knife, the broken ends of fractured bone of pilose antler is immersed in 0.5 in 50 DEG C of hot wine
It~l hours, is sliced after pilose antler softening, it is spare to be ground into pilose antler powder;By ginseng, Radix Astragali, Gorgon fruit, the fruit of Cherokee rose, psoralea corylifolia, Tu
Son, Chinese yam, grass-leaved sweetflag, Chinese ephedra, merging vessel are interior to add cold water soak half an hour, the water of 8 times of medicine weight is added, after being boiled by fire
It is 20 minutes pan-fried to change small fire, concoction is filtered out, the water of 6 times of medicine weight is added, it is multiple to decoct once, concoction twice is poured in obtaining together
Medicine decoction, while taking the pilose antler powder of parts by weight developed to be added in the traditional Chinese herbal decoction of tanning and obtaining oral decoction;
3) evodia rutaecarpa of parts by weight, the root of Dahurain angelica, white pepper mixed in proportion, smashed, being ground up, sieved into herb powder, added
With appropriate light-coloured vinegar to paste is tuned into, navel medicine for external application is obtained;
4) honeycomb of parts by weight is put in iron pan and is slowly heated, until fine grinding while hot when crisp, by the mountain of parts by weight
Powder one is made in short, bristly hair or beard, Chinese yam, the membrane of a chicken's gizzard jointly, and powder one and the honeycomb powder of parts by weight obtain dietotherapy medicinal powder after mixing.
The advantageous effect further illustrated the present invention with reference to clinical data, but the invention is not limited in following clinics
Data:
Basic document:Enruesis is treated in June, 2013~2016 year 2 months using the above-mentioned prescription of the embodiment of the present invention 1
699, basic clinical data is as follows:Wherein man 378, female 321, the age between 3~45 years old, average age 29 years old.
Therapy:
Treatment group's whole case history uses oral decoction, and one one, one to take orally at twice.
Control group combines navel medicine for external application, vola bubble foot medicine and dietotherapy medicine to participate in treatment on the basis of oral decoction.
Above two groups equal 14 days courses for the treatment of, the effect of 2 courses for the treatment of are observed continuously.
Treatment results and efficacy determination:Curative effect determinate standard is drafted with reference to clinical disease diagnosis according to improvement standard is cured.
It cures:Original symptom disappears, oneself can wake up urination, then bed-wetting phenomenon does not occur;
It improves:Original symptom mitigates, and bed-wetting number is reduced;
In vain:Original symptom is without improvement.
Treatment results are shown in Table 1.
1.2 groups of curative effects of table compare
Group | Number of cases | It cures | It improves | In vain | It is efficient |
Treatment group | 239 | 138 | 57 | 14 | 81.58 |
Control group | 460 | 302 | 129 | 29 | 93.69 |
Note:Treatment group is compared with the control group:P<0.05
The clinical typical case summary cured:
Interrogation description before treatment:
Korea Spro, man, 12 years old, on April 16th, 2011 came our hospital's outpatient service with his father, main suit:Continue to aggravate in more than ten years of the enuresis
Half a year, symptoms include:Thin and weak to can't bear, Mian Se Koushi are white, readme:The frequent enuresis in sleeping, notably a night, urine was clear and grows, and rear of waking up is felt for several times,
Spiritlessness and weakness, shortness of breath lazyness speech, colourless limb is cold, lassitude in loin and legs, receives poor loose stool, and intelligence is poor, and tongue nature is light, and tongue is thin white, deep thready pulse without
Power.
Therapeutic process records:
It is dialectical:Kidney Spleen-Qi Deficiency.
The rules for the treatment of:Warming kidney and strengthening spleen consolidates contracting spring.
Prescription:Chinese herbs decoction coordinates navel administration, vola bubble foot to be subject to dietotherapy medicine.
After half a month, the enuresis significantly reduces for medication, disappears from symptom is lost, and shortness of breath lazyness speech is clearly better, and food of receiving is fragrant, and four limbs are bright
Aobvious strong earlier above, complexion is slightly ruddy.
No more side effects, following the service two weeks, advises and avoids cold and uncooked food, mostly edible temperature compensation food.
It is tracked after healing:
Follow-up no relapse after half a year.
Example the above is only the implementation of the present invention is not intended to limit the scope of the invention, every to utilize this hair
Equivalent structure or equivalent flow shift made by bright description is applied directly or indirectly in other relevant technology necks
Domain is included within the scope of the present invention.
Claims (7)
1. a kind of Chinese medicine composition for treating enruesis, which is characterized in that include the component of following parts by weight:2~4 parts of ginseng,
9~11 parts of Radix Astragali, 11~13 parts of Gorgon fruit, 5~7 parts of the fruit of Cherokee rose, 4~6 parts of psoralea corylifolia, 8~10 parts of Semen Cuscutae, 8~10 parts of Chinese yam,
8~10 parts of grass-leaved sweetflag, 1~3 part of pilose antler, 4~6 parts of Chinese ephedra, 1~3 part of evodia rutaecarpa, 0.5~1.5 part of the root of Dahurain angelica, white pepper 0.5~
1.5 parts, 3~5 parts of honeycomb, 3~5 parts of hawthorn, 3~5 parts of Chinese yam, 3~5 parts of the membrane of a chicken's gizzard, 18~22 parts of the bletilla striata.
2. a kind of Chinese medicine composition for treating enruesis according to claim 1, which is characterized in that including following parts by weight
Component:3 parts of ginseng, 10 parts of Radix Astragali, 12 parts of Gorgon fruit, 6 parts of the fruit of Cherokee rose, 5 parts of psoralea corylifolia, 9 parts of Semen Cuscutae, 9 parts of Chinese yam, grass-leaved sweetflag
9 parts, 2 parts of pilose antler, 5 parts of Chinese ephedra, 2 parts of evodia rutaecarpa, 1 part of the root of Dahurain angelica, 1 part of white pepper, 4 parts of honeycomb, 4 parts of hawthorn, 4 parts of Chinese yam, in chicken
Golden 4 parts, 20 parts of the bletilla striata.
3. a kind of Chinese medicine composition for treating enruesis according to claim 1, which is characterized in that further include following weight
The component of part:20 parts of the bletilla striata, 10 parts of grass-leaved sweetflag, 10 parts of psoralea corylifolia, 50 parts of Radix Astragali, for steeping foot medicine after said components are milled.
4. a kind of preparation method of Chinese medicine composition that treating enruesis, which is characterized in that include the following steps:
1) each component is weighed according to the weight part ratio of component;
2) pilose antler is burned into pilose antler fine hair with no pyrotechnics, is shaved with bamboo knife, the broken ends of fractured bone of pilose antler is immersed in 0.5~l in 50 DEG C of hot wine
Hour, it is sliced after pilose antler softening, it is spare to be ground into pilose antler powder;By ginseng, Radix Astragali, Gorgon fruit, the fruit of Cherokee rose, psoralea corylifolia, Semen Cuscutae, mountain
In merging vessel plus cold water soak half an hour, the water of 8 times of medicine weight is added in medicine, grass-leaved sweetflag, Chinese ephedra, small with changing after being boiled by fire
Fire is 20 minutes pan-fried, and concoction is filtered out, and the water of 6 times of medicine weight is added, multiple pan-fried primary, and concoction twice is poured on and obtains Chinese medicinal decoction together
Agent, while taking the pilose antler powder of parts by weight developed to be added in the traditional Chinese herbal decoction of tanning and obtaining oral decoction;
3) evodia rutaecarpa of parts by weight, the root of Dahurain angelica, white pepper mixed in proportion, smashed, being ground up, sieved into herb powder, being fitted
Light-coloured vinegar is measured to paste is tuned into, obtains navel medicine for external application;
4) honeycomb of parts by weight is put in iron pan and is slowly heated, until fine grinding while hot when crisp, by the hawthorn of parts by weight, mountain
Powder one is made in medicine, the membrane of a chicken's gizzard jointly, and powder one and the honeycomb powder of parts by weight obtain dietotherapy medicinal powder after mixing.
5. a kind of preparation method of Chinese medicine composition for treating enruesis according to claim 4, which is characterized in that step
2) oral decoction described in is divided into two parts, respectively takes portion sooner or later.
6. a kind of preparation method of Chinese medicine composition for treating enruesis according to claim 4, which is characterized in that step
3) the navel medicine for external application described in spreads on umbilical region, sticks every night, and m seq is removed, once a day.
7. a kind of preparation method of Chinese medicine composition for treating enruesis according to claim 4, which is characterized in that step
4) the dietotherapy medicinal powder described in respectively takes 4g daily morning and evening, can be mixed into white sugar boiling water to take after mixing it with water or can be mixed into congee and take.
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