CN108434281A - A kind of Chinese medicine composition of Neurology treatment Parkinson - Google Patents

A kind of Chinese medicine composition of Neurology treatment Parkinson Download PDF

Info

Publication number
CN108434281A
CN108434281A CN201710329194.3A CN201710329194A CN108434281A CN 108434281 A CN108434281 A CN 108434281A CN 201710329194 A CN201710329194 A CN 201710329194A CN 108434281 A CN108434281 A CN 108434281A
Authority
CN
China
Prior art keywords
parts
radix
chinese medicine
rhizoma
medicine composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201710329194.3A
Other languages
Chinese (zh)
Inventor
李婷
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to CN201710329194.3A priority Critical patent/CN108434281A/en
Publication of CN108434281A publication Critical patent/CN108434281A/en
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/888—Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
    • A61K36/8884—Arisaema, e.g. Jack in the pulpit
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/26—Iron; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/02—Medicinal preparations containing materials or reaction products thereof with undetermined constitution from inanimate materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/58—Reptiles
    • A61K35/586—Turtles; Tortoises, e.g. terrapins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/618—Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/62—Leeches; Worms, e.g. cestodes, tapeworms, nematodes, roundworms, earth worms, ascarids, filarias, hookworms, trichinella or taenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/63—Arthropods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/63—Arthropods
    • A61K35/646—Arachnids, e.g. spiders, scorpions, ticks or mites
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06—Fungi, e.g. yeasts
    • A61K36/07—Basidiomycota, e.g. Cryptococcus
    • A61K36/076—Poria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/13—Coniferophyta (gymnosperms)
    • A61K36/15—Pinaceae (Pine family), e.g. pine or cedar
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232—Angelica
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/236—Ligusticum (licorice-root)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/237—Notopterygium
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/26—Aristolochiaceae (Birthwort family), e.g. heartleaf
    • A61K36/268—Asarum (wild ginger)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/282—Artemisia, e.g. wormwood or sagebrush
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/284—Atractylodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/286—Carthamus (distaff thistle)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/35—Caprifoliaceae (Honeysuckle family)
    • A61K36/355—Lonicera (honeysuckle)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/41—Crassulaceae (Stonecrop family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/47—Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481—Astragalus (milkvetch)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484—Glycyrrhiza (licorice)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/51—Gentianaceae (Gentian family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/537—Salvia (sage)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/539—Scutellaria (skullcap)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/59—Menispermaceae (Moonseed family), e.g. hyperbaena or coralbead
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/736—Prunus, e.g. plum, cherry, peach, apricot or almond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/80—Scrophulariaceae (Figwort family)
    • A61K36/804—Rehmannia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/80—Scrophulariaceae (Figwort family)
    • A61K36/808—Scrophularia (figwort)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/888—Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10—Preparation or pretreatment of starting material
    • A61K2236/17—Preparation or pretreatment of starting material involving drying, e.g. sun-drying or wilting
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50—Methods involving additional extraction steps
    • A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying

Abstract

The invention discloses the Chinese medicine composition that a kind of Neurology treats Parkinson, the quality proportioning of traditional Chinese medicine composite composition is：Radix Salviae Miltiorrhizae, honey-fried licorice root, radix scutellariae, Rhizoma Atractylodis Macrocephalae, Poria cocos, Radix Rehmanniae, radix rehmanniae preparata, asarum, Radix Astragali, earthworm, Rhizoma Chuanxiong, safflower, peach kernel, rhizoma typhonii, the larva of a silkworm with batrytis, scorpio, Radix Angelicae Pubescentis, Radix Angelicae Sinensis, bark of ash, Rhizoma Et Radix Notopterygii, Herba Lycopodii, radix scrophulariae, raw sienna, Sagina subulata, oriental wormwood, arisaema cum bile, korean pine seed, the fruit of Rangoon creeper, moutan bark, honeysuckle, stringy stonecrop, milk thistle, the root of fangji, calcined Dragon's bone, calcined oyster shell, turtle shell；The present invention is all made of natural Chinese medicine material, and selected medicinal material compatibility is suitable, meets traditional Chinese medicine and pharmacy and modern medical theory, to treatment Parkinson's disease tool by unique curative effect, manner of formulation is simple, good absorption effect, has blood circulation promoting and enriching, medicine source wide, it is at low cost, it is significant in efficacy, mild in medicine property and；It is without side-effects, it is safe.

Description

A kind of Chinese medicine composition of Neurology treatment Parkinson
Technical field
The present invention is bright to belong to field of Chinese medicinal composition, and in particular to a kind of Chinese traditional medicine composition of Neurology treatment Parkinson Object.
Background technology
Parkinson's disease also known as shaking plasy are one of most common neurodegenerative diseases.Parkinson's disease be to tremble, Myotonia, the chronic neurological degenerative disease that movement is reduced and abnormal posture is characterized, are mainly in the middle-aged and the old, with population Aging is on the rise, and the incidence of this disease will increasingly rise.Doctor trained in Western medicine wouldn't can effect a radical cure Parkinson's disease, the treatment to patient, Mainly mitigate slight illness, disease is delayed to develop.
Chinese medicine thinks that Parkinson is wind, void, phlegm, the stasis of blood, defective ejaculation, dirty empty meaning sheet, inherently elaborates the cause of disease trembled With pathology.Shen controls bone, store essential substances give birth to marrow lead to brain, deficiency of kidney-essence cannot go up honor in brain, cannot be by marrow tonifying brain with essence.Brain be marrow it Sea, marrow, which lacks brain and loses marrow, supports, and muscle is become homeless profit, and sees arrested anxious, trembling and dizziness.Spleen governing muscles are source of generating QI and blood, spleen deficiency, cereal nutrient It is unable to transporting, cannot change and be " red ", blood cannot go up honor in brain, and brain is hollow, flourish cannot support muscle, and see muscle rigidity It is tetanic.According to theory of traditional Chinese medical science, for the pathogenesis of Parkinson, with blood circulation promoting and enriching, tonifying liver is empty, calming liver to stop endogenous wind, and nourshing kidney cerebrum tonifying is good for Spleen QI invigorating, it is eliminating dampness and eliminating phlegm be principle of reatment, to achieve the purpose that treating both manifestation and root cause of disease.
Invention content
In view of the above problems, the present invention provides the Chinese medicine composition that a kind of Neurology treats Parkinson, it is all made of day Right Chinese medicine material, selected medicinal material compatibility is suitable, meets traditional Chinese medicine and pharmacy and modern medical theory, to treatment Parkinson's disease tool by Unique curative effect, manner of formulation is simple, good absorption effect, has blood circulation promoting and enriching, medicine source is wide, at low cost, significant in efficacy, mild in medicine property With；It is without side-effects, it is safe, it can effectively solve the problems in background technology.
To achieve the goals above, the technical solution adopted by the present invention is as follows：In a kind of Neurology treatment Parkinson Drug composition, the Chinese medicine composition are prepared using multigroup traditional Chinese medicine composite, traditional Chinese medicine composite composition Quality proportioning is：
4-6 parts of Radix Salviae Miltiorrhizae, 3-5 parts of honey-fried licorice root, 3-5 parts of radix scutellariae, 3-5 parts of Rhizoma Atractylodis Macrocephalae, 2-4 parts of Poria cocos, 2-4 parts of Radix Rehmanniae, radix rehmanniae preparata 2-4 It is part, 2-4 parts of asarum, 2-4 parts of Radix Astragali, 2-4 parts of earthworm, 3-5 parts of Rhizoma Chuanxiong, 2-4 parts of safflower, 3-5 parts of peach kernel, 2-4 parts of rhizoma typhonii, white 3-5 parts of stiff silkworm, 4-6 parts of scorpio, 2-4 parts of Radix Angelicae Pubescentis, 3-5 parts of Radix Angelicae Sinensis, 2-4 parts of bark of ash, 2-4 parts of Rhizoma Et Radix Notopterygii, 3-5 parts of Herba Lycopodii, radix scrophulariae 4-6 parts, 3-5 parts of raw sienna, 2-4 parts of Sagina subulata, 2-4 parts of oriental wormwood, 3-5 parts of arisaema cum bile, 4-6 parts of korean pine seed, 2-4 parts of the fruit of Rangoon creeper, 2-4 parts of moutan bark, 4-8 parts of honeysuckle, 3-5 parts of stringy stonecrop, 2-4 parts of milk thistle, 2-4 parts of the root of fangji, 2-10 parts of calcined Dragon's bone, calcined oyster shell 2-10 parts, 2-10 parts of turtle shell.
According to above-mentioned technical proposal, the earthworm is earthworm powder.
According to above-mentioned technical proposal, the honeysuckle is dry for honeysuckle, and is by with adopting with solarization, thinly by honeysuckle It is sprinkled upon on pallet, pallet is placed in ventilation area without shade, Bei Gaonan is low, is divulged information with profit；To eighty per cant it is dry when, can stir or close disk Drying, night or chance rain will be placed on pallet within doors in time, avoid the discoloration that gets wet, fine day from continuing to dry, until drying；It dries It is dry：Kept when room temperature is increased to 40 DEG C or so general 6 it is small when, room temperature is maintained at 40~45 DEG C, waits for that the aqueous vapor of fresh flower is most of Exclude, be such as not achieved 8 one-tenth it is dry more than, the time of 40~45 DEG C of temperature control need to be extended, then room temperature is mentioned 55~60 DEG C, honeysuckle is fast Rapid-curing cutback is dry；Entire drying course is manufactured after need to generally lasting 18 hours.
A kind of Chinese medicine composition preparation method of Neurology treatment Parkinson, includes the following steps：
(1) dispensing：Each raw material is weighed by formula, removal of impurities is dried rear spare；
(2) it crushes：By scorpio, Radix Angelicae Pubescentis, Radix Angelicae Sinensis, bark of ash, Rhizoma Et Radix Notopterygii, Herba Lycopodii, radix scrophulariae, raw sienna, Sagina subulata, oriental wormwood, courage After Southern Star, korean pine seed, the fruit of Rangoon creeper, moutan bark, honeysuckle, stringy stonecrop, milk thistle, the root of fangji, calcined Dragon's bone, calcined oyster shell and turtle shell crush Screening is crossed, obtains mixed-powder after mixing；
(3) extracting solution is prepared：Mixed-powder in step (2) is added to the water of 10-12 times of its total weight, be boiled by fire 3- Continue to decoct 20-30min after 5min, 4-6 times of water is added after filtering, decocts 20-30min, filters again, merges filtrate twice It is spare to obtain extracting solution A；
(4) mixed solution is prepared：By Radix Salviae Miltiorrhizae, honey-fried licorice root, radix scutellariae, Rhizoma Atractylodis Macrocephalae, Poria cocos, Radix Rehmanniae, radix rehmanniae preparata, asarum, Radix Astragali, Dragon, Rhizoma Chuanxiong, safflower, peach kernel, rhizoma typhonii, arisaema cum bile and the larva of a silkworm with batrytis are put into its 12-15 times of weight, volume fraction after mechanical crushing To impregnate 20-24h in 98% ethanol solution, it is heated to reflux 2-3 times, it is spare obtains mixed solution B；
(5) it mixes：Mixed solution B in extracting solution A and step (4) in step (3) is added in blender together, It is stirred under the rotating speed of 600-800r/min, obtains mixed solution；
(6) it concentrates：Mixed solution low temperature in step (5) is concentrated into the 1/10 of original volume, is obtained in the present invention Drug composition；
(7) it packs：Obtained Chinese medicine composition in step (6) is packed；
According to above-mentioned technical proposal, the screening in the step (2) is used for 240-280 mesh sieve.
According to above-mentioned technical proposal, the time that the step (5) is stirred in blender is 15-25min.
According to above-mentioned technical proposal, the packing device of the step (7) is automatic packaging machine.
The pharmacological activity of each traditional Chinese medicine composite is as follows in the present invention：
Radix Salviae Miltiorrhizae：Hardship is slightly cold.Converge to heart and liver channels.Promoting blood circulation for regulating menstruation, stasis-dispelling and pain-killing, cool blood to disappear carbuncle, relieving restlessness that clears away heart-fire.Cure mainly month warp It is uncomfortable, Amenorrhea, dysmenorrhoea, postpartum stasis caused pain , lumps in the chest and abdomen, chest and abdomen shouting pain, arthralgia pain due to rheumatism, sore carbuncle swells, pyreticosis divine coma, palpitaition Insomnia；Hepatic sclerosis, coronary heart disease.
Honey-fried licorice root：Sweet and neutral.The thoughts of returning home, lung, spleen, stomach.It invigorates the spleen and benefits qi, clearing heat and detoxicating, expelling phlegm and arresting coughing, relieving spasm to stop pain reconciles All medicines.For weakness of the spleen and the stomach, lassitude hypodynamia, palpitation, coughing with a lot of sputum, gastral cavity abdomen, four limbs contraction, carbuncle sore tumefacting virus, alleviation It is drug toxicity, strong.
Radix scutellariae：There are heat-clearing and damp-drying drug, cool blood tocolysis, detoxicating functions.Cure mainly the warm heat disease, infection of the upper respiratory tract, cough with lung heat, wet The diseases such as hot jaundice, pneumonia, dysentery, hemoptysis, hot eyes, fetal irritability, hypertension, carbuncle swells furuncle sore.Effect：Have with teasel root tocolysis it Work(, with controlling fetal irritability.
Rhizoma Atractylodis Macrocephalae：Tonifying spleen, beneficial stomach, eliminating dampness, and in, tocolysis.Control deficient QI of the spleen and stomach, do not feel like eating, burnout lacks gas, empty swollen, diarrhea, Phlegm and retained fluid, oedema, jaundice, arthritis with fixed pain caused by dampness, difficult urination is dizzy, spontaneous perspiration, and nausea is uneasy.Poria cocos：Eliminating dampness and diuresis, beneficial spleen and stomach, calming heart peace God.Difficult urination is controlled, oedema turgor, phlegm and retained fluid cough is inverse, the sound of vomiting of vomitting, diarrhea, seminal emission, stranguria with turbid discharge, and palpitation with fear is forgetful.
Radix Rehmanniae：Nature and flavor：Sweetness and bitterness, it is cool.Fever due to yin deficiency is controlled, is quenched one's thirst, is spitted blood, bleeding from five sense organs or subcutaneous tissue, metrorrhagia, irregular menstruation, fetal irritability, the moon Hinder constipation.
Radix rehmanniae preparata：It is sweet in flavor；It is warm-natured.Return liver；Kidney channel.Enrich blood moist；Beneficial to spirit and marrow；For blood deficiency chlorosis；Dizziness palpitaition；Menstruation It is uncomfortable；It collapses more than；Liver-kidney Yin deficiency；Hectic fever night sweat；Seminal emission impotence；Infertility；Irregular menstruation；Metrostaxis；Soreness and weakness of waist and knees；Ear Ring is deaf；It is dim-sighted；Poliosis；It quenches one's thirst；Constipation；Syndrome characterized by dyspnea.
Asarum：Relieving exterior syndrome and dispelling cold, wind-expelling pain-stopping is sensible, warming lung and resolving fluid.For anemofrigid cold, have a headache, toothache, nasal congestion, Allergic rhinitis, nasosinusitis, arthralgia pain due to rheumatism, sputum cough.
Radix Astragali：It is sweet, tepor.There are enhancing body's immunity, liver protection, diuresis, anti-aging, resisting stress, decompression and wide Antibacterial action.Jishengshenqiwan albuminuria can be eliminated, myocardial contractive power is enhanced, adjusts blood-sugar content.Radix Astragali can not only be expanded Coronary artery improves myocardial blood supply, improves immune function, and be capable of the process of delaying cell aging.
Earthworm：Cure mainly high fever frightened epilepsy, move wind twitch, pyreticosis shy mad, child convulsion, cough and asthma, headache and hot eyes, abscess of throat, Urinary obstruction, pain in rheumatoid joints, the diseases such as hemiplegia.
Rhizoma Chuanxiong：Acrid flavour, it is warm-natured；Return liver, courage, the heart channel of Hang-Shaoyin；Gas perfume (or spice) rises to dissipate, and there is blood-activating and qi-promoting, the effect of wind-expelling pain-stopping to cure mainly the moon Through uncomfortable, dysmenorrhoea, Amenorrhea, difficult labour, placenta retension, lochia abdominal pain, lump, heart pain in chest and hypochondrium, traumatic injury swelling and pain, headache Vertigo and head dark, wind-cold-dampness arthralgia, extremity numbness, ulcer sores.
Safflower：Invigorate blood circulation, stasis eliminatings analgesic.Controlling through closing , Disorder lumps in the abdomen, difficult labour, stillborn foetus, disease that postpartum lochia can't go, hemostasis are had a pain, carbuncle It is swollen, injury from falling down.
Peach kernel：Promoting blood circulation relaxes bowel.For Amenorrhea, dysmenorrhoea , wei lump in the abdomen lump in the abdomens, injury from falling down, dry constipation of intestines.Peach kernel Property sweet flat, bitter, enter lung, liver, large intestine channel；There is the effect of blood-breaking row stasis of blood, moisturize laxation；Controlling through closing, dysmenorrhoea, lump in the abdomen lump in the abdomen lump in the abdomen, fall Beat damage, dry constipation of intestines.
Rhizoma typhonii：It is acrid flavour, sweet, it is warm-natured, it is toxic.Return stomach, Liver Channel.It is eliminating dampness and eliminating phlegm, expelling wind and relieving convulsion, detoxicating and resolving a mass analgesic.It is main Control middle air port eye caused by wind phlegm tiltedly, infantile convulsion epilepsy, lockjaw, migraine etc.；Tuberculous lymphadenitis, swollen ulcer drug and venomous snake bite.
Arisaema cum bile：Bitter, micro-pungent, it is cool.Return lung, liver, the spleen channel.Clearing heat and eliminating phlegm, dispelling wind and relieving convulsion.For phlegm-heat cough, Huang of coughing up phlegm It is thick, stroke and phlegm confusing heart, demented frightened epilepsy.Enter the warp of conscience lung three, clearing away fire and eliminating phlegm is relieving convulsion to determine epilepsy, controls stroke and phlegm confusing heart, infantile convulsion top epilepsy, convulsive seizure due to phlegm-fire It breathes with cough, the dizzy dusk Southern Star clearing heat and eliminating phlegm of intermittent headache, dispelling wind and relieving convulsion.For phlegm-heat cough, cough up phlegm yellow thick, stroke and phlegm confusing heart, demented frightened epilepsy.
The larva of a silkworm with batrytis：Liver；Lung；Stomach, acrid flavour；It is salty；It is mild-natured；Expelling wind and relieving convulsion；Reducing phlegm and resolving masses；Removing toxic substances relieving sore-throat.Main twitch； Middle air port eye is tiltedly；Migraine and general headache；Abscess of throat；Scrofula；Mumps；Rubella；Sore.
Scorpio：Scorpio is classified as medicine for calming liver and calming endopathic wind, and acrid flavour is mild-natured, toxic, return liver warp.Stop with Inflammation Zhijing, dredging collateral Bitterly, the effect of detoxicating and resolving a mass.The effect of scorpio be it is pungent dissipate, string thoroughly, attack poison, to control the key medicine of exogenous wind.It is usually used in apoplexy, shies Wind, lockjaw, bi Zheng can be used for sore carbuncle, tuberculosis, venomous snake bite.
Radix Angelicae Pubescentis：Acrid flavour, hardship, slightly warm in nature.Return kidney, bladder warp.Dispelling wind and eliminating dampness, arthritis analgesic.For wind-cold-dampness arthralgia, pain is washed Bitterly, few the moon volt wind headache, chill hold wet headache under the arm.
Radix Angelicae Sinensis：Replenishing and activating blood, menstruction regulating and pain relieving relax bowel.For blood deficiency chlorosis, dizziness palpitaition, irregular menstruation, Amenorrhea pain Through, asthenia cold abdominalgia, dry constipation of intestines, arthralgia pain due to rheumatism, injury from falling down, ulcer sores.
Bark of ash：It is pungent, bitter, it is slightly cold.Return stomach, Liver Channel, gallbladder channel.Wind-damp dispelling, relaxing muscles and tendons network, clearind deficient heat.For arthralgia pain due to rheumatism, muscle Arteries and veins contraction, skeletal pain, afternoon tidal fever, infantile malnutrition generates heat.
Rhizoma Et Radix Notopterygii：Dissipate exterior cold, wind-damp dispelling, sharp joint.Cure cold chill, headache and adiapneustia, wind-cold-dampness arthralgia, and item strengthening tendons are anxious, joint Ache, geomantic omen edema, skin sore.For impotence and seminal emission, enuresis frequent micturition, waist and knee crymodynia, deficiency of the kidney and dyspnea, Diarrhoea；External application Curing vitiligo, alopecia areata.Relieving exterior syndrome and dispelling cold, expelling wind and eliminating dampness, analgesic.
Herba Lycopodii：Cool in nature, mildly bitter flavor enters liver, spleen two passes through；Containing quaternary amine alkaloid, the predominantly former small-sized palm leaf root of fangji Secondly alkali and a small amount of jateorrhizine are the magnoflorine of aporphine type and choline, Herba Lycopodii alkali, Herba Lycopodii lactone, the lobus cardiacus of amine The ingredients such as wide muscle alcohol, cupreol, glucan, have effects that relaxing tendons and activating collaterals, wind-expelling pain-stopping, for treating arthralgia pain due to rheumatism, sitting The diseases such as osteoneuralgia, lumbar muscle strain, traumatic injury.
Radix scrophulariae：Enriching yin, fall fire, relieving restlessness, removing toxic substances；Consumption of YIN caused by febrile disease is controlled, tongue unravels silk polydipsia, and macular eruption, hectic fever due to yin labor is hot, and night sleeps not rather, Spontaneous sweating, Tianjin hinder constipation, hematemesis and epistaxis, abscess of throat, carbuncle swells, scrofula, febrile virulent maculae, hot eyes, diphtheria, sore.
Raw sienna：Hardship is trembled with fear.Return liver, the heart channel of Hang-Shaoyin；Calming the liver, drop is inverse, hemostasis；For having a headache caused by liver-yang hyperactivity, dizzy It is dizzy, the circulation of vital energy in the wrong direction is panted, blood-head is spitted blood, bleeding from five sense organs or subcutaneous tissue etc..
Sagina subulata：It is cool in nature；Sweet-bitter flavor；Return liver, lung channel；Calming liver and clearing heat, promoting diuresis to remove toxic substance；Control enteritis, dysentery, infectiousness liver Inflammation, nephritic dropsy, urinary tract infections, infantile malnutrition, pinkeye mesh screen, aphtha head sore, nameless sores or boils.
Oriental wormwood：Cold nature；It is bitter, pungent；Returns spleen, stomach, liver, gallbladder channel；Clearing heat and promoting diuresis；Removing jaundice.It cures mainly：Jaundice, difficult urination, Itchy sore, infectious jaundice type hepatitis.
Moutan bark：It is cold in nature, bitter；It is cool；It is slightly cold.The thoughts of returning home；Liver；Kidney；Lung channel；Clearing heat and cooling blood；Promoting blood circulation to remove blood stasis.Warm heat disease heat enters Blood system；Macular eruption；Hematemesis；Pyreticosis later stage hot Fu Yin distributions heat；Deficiency of Yin osteopyrexia and fever；Amenorrhea due to stagnation of blood；Dysmenorrhoea；Carbuncle sore tumefacting virus；Fall and flutters It is grieved；Beriberoid pyretic arthralgia.
Peach kernel：With promoting blood circulation, relax bowel, relieving cough and asthma effect；For closed dysmenorrhea, lump in the abdomen lump in the abdomen lump in the abdomen, lung carbuncle Acute appendicitis, injury from falling down, dry constipation of intestines, cough and asthma.
Korean pine seed：Nutrient solution relieves dizziness, high fever, infantile convulsions, epilepsy, etc., moistening lung, and laxation controls wandering arthritis, dizzy, cough caused by dryness, spits blood, constipation.
The fruit of Rangoon creeper：Desinsection, disperse accumulation, invigorating the spleen.Roundworm abdominal pain, infantile malnutrition are controlled, breast food is stagnated, abdominal distension, rush down dysentery.
Honeysuckle：Sweet, slight bitter, faint scent is pungent, trembles with fear.Return lung, stomach, the heart, large intestine channel；It is clearing heat and detoxicating, wind-heat dissipating.For carbuncle Swollen furunculosis, larynx numbness, erysipelas, toxic-heat and blood stasis, anemopyretic cold, warm disease heating.
Stringy stonecrop：Clearing heat and promoting diuresis；Removing toxicity for detumescence；Hemostasis blood-nourishing.Main jaundice with damp-heat pathogen；Gonorrhoea；Rush down dysentery；Lung carbuncle；Acute appendicitis；Boil Pyogenic infections；Snakebite and bugbite；Scald；Abscess of throat；Canker sore and eczema；Herpes zoster.
Milk thistle：Early stage of pyogenic infection of skin and erysipelas can be treated, hepatopathy, spleen disease gall stone, jaundice and chronic cough are used for；Heat-clearing solution Poison, liver protection, cholagogic protect brain, anti-X-ray；
The root of fangji：Property it is bitter, it is pungent, tremble with fear；Return bladder warp, kidney channel, the spleen channel；Cure mainly pain in rheumatoid joints；Damp and hot limbs pain；Water It is swollen；Difficult urination；Tinea pedis is wet swollen.
Calcined Dragon's bone：It is sweet puckery, it puts down.The thoughts of returning home, liver, kidney, large intestine channel.Tranquillizing the mind by relieving convulsion, arrest sweating controlling nocturnal emission with astringent drugs, stop blooding puckery intestines, myogenic sore. It is demented to control frightened epilepsy, palpitation is forgetful, insomnia and dreamful sleep, spontaneous sweating, and stranguria with turbid discharge of passing out semen, hematemesis is had blood in stool, and under uterine bleeding band, rush down dysentery rectal prolapse is burst Ulcer does not close up long.
Calcined oyster shell：Taste is salty；Cold nature.Return liver, courage, kidney channel.There is transquilization with heavy material, calming the liver, convergence astringent method effect, can use It controls confused and worried, insomnia of palpitating with fear, hyperactivity of yang due to yin deficiency, have a dizzy spell and various slip cards.
Turtle shell：It is salty, cold.Return liver and kidney channel.Nourishing and suppressing Yang, softening and resolving hard mass are brought down a fever except steaming.For fever due to yin deficiency, the hot bone of labor It steams, endogenous deficient wind, Amenorrhea , wei lumps in the abdomen, chronic malaria malaria with abdominal mass.
Beneficial effects of the present invention：
The present invention is all made of natural Chinese medicine material, and selected medicinal material compatibility is suitable, meets traditional Chinese medicine and pharmacy and modern medicine and pharmacology Theory, to treatment Parkinson's disease tool by unique curative effect, manner of formulation is simple, good absorption effect, has a blood circulation promoting and enriching, medicine source is wide, It is at low cost, it is significant in efficacy, mild in medicine property and；It is without side-effects, it is safe.
Description of the drawings
Fig. 1 is preparation flow figure of the present invention.
Specific implementation mode
In order to make the purpose , technical scheme and advantage of the present invention be clearer, with reference to embodiments, to the present invention It is further elaborated.It should be appreciated that the specific embodiments described herein are merely illustrative of the present invention, it is not used to Limit the present invention.
Embodiment 1：
Referring to Fig. 1, the present invention provides a kind of Chinese medicine composition of Neurology treatment Parkinson, the Chinese medicine composition It is to be prepared using multigroup traditional Chinese medicine composite, the quality proportioning of traditional Chinese medicine composite composition is：
4 parts of Radix Salviae Miltiorrhizae, 3 parts of honey-fried licorice root, 3 parts of radix scutellariae, 3 parts of Rhizoma Atractylodis Macrocephalae, 2 parts of Poria cocos, 2 parts of Radix Rehmanniae, 2 parts of radix rehmanniae preparata, 2 parts of asarum, Huang 2 parts of stilbene, 2 parts of earthworm, 3 parts of Rhizoma Chuanxiong, 2 parts of safflower, 3 parts of peach kernel, 2 parts of rhizoma typhonii, 3 parts of the larva of a silkworm with batrytis, 4 parts of scorpio, 2 parts of Radix Angelicae Pubescentis, when Return 3 parts, 2 parts of bark of ash, 2 parts of Rhizoma Et Radix Notopterygii, 3 parts of Herba Lycopodii, 4 parts of radix scrophulariae, 3 parts of raw sienna, 2 parts of Sagina subulata, 2 parts of oriental wormwood, arisaema cum bile 3 Part, 4 parts of korean pine seed, 2 parts of the fruit of Rangoon creeper, 2 parts of moutan bark, 4 parts of honeysuckle, 3 parts of stringy stonecrop, 2 parts of milk thistle, 2 parts of the root of fangji, calcined Dragon's bone 2 parts, 2 parts of calcined oyster shell, 2 parts of turtle shell.
According to above-mentioned technical proposal, the earthworm is earthworm powder, and the honeysuckle is dry for honeysuckle, and be by with adopt with It shines, honeysuckle is thinly sprinkled upon on pallet, pallet is placed in ventilation area without shade, Bei Gaonan is low, is divulged information with profit；It is dry to eighty per cant When, can stir and either close disk drying night or meet rain and pallet is placed within doors in time, avoid the discoloration that gets wet, fine day after Continuous drying, until drying；Drying：Kept when room temperature is increased to 40 DEG C or so general 6 it is small when, room temperature is maintained at 40~45 DEG C, Wait for that the aqueous vapor of fresh flower largely excludes, be such as not achieved 8 one-tenth it is dry more than, the time of 40~45 DEG C of temperature control need to be extended, then room temperature is carried To 55~60 DEG C, honeysuckle is dried rapidly；Entire drying course is manufactured after need to generally lasting 18 hours.
A kind of Chinese medicine composition preparation method of Neurology treatment Parkinson, includes the following steps：
(1) dispensing：Each raw material is weighed by formula, removal of impurities is dried rear spare；
(2) it crushes：By scorpio, Radix Angelicae Pubescentis, Radix Angelicae Sinensis, bark of ash, Rhizoma Et Radix Notopterygii, Herba Lycopodii, radix scrophulariae, raw sienna, Sagina subulata, oriental wormwood, courage After Southern Star, korean pine seed, the fruit of Rangoon creeper, moutan bark, honeysuckle, stringy stonecrop, milk thistle, the root of fangji, calcined Dragon's bone, calcined oyster shell and turtle shell crush Screening is crossed, obtains mixed-powder after mixing；
(3) extracting solution is prepared：Mixed-powder in step (2) is added to the water of 10-12 times of its total weight, be boiled by fire 3- Continue to decoct 20-30min after 5min, 4-6 times of water is added after filtering, decocts 20-30min, filters again, merges filtrate twice It is spare to obtain extracting solution A；
(4) mixed solution is prepared：By Radix Salviae Miltiorrhizae, honey-fried licorice root, radix scutellariae, Rhizoma Atractylodis Macrocephalae, Poria cocos, Radix Rehmanniae, radix rehmanniae preparata, asarum, Radix Astragali, Dragon, Rhizoma Chuanxiong, safflower, peach kernel, rhizoma typhonii, arisaema cum bile and the larva of a silkworm with batrytis are put into its 12-15 times of weight, volume fraction after mechanical crushing To impregnate 20-24h in 98% ethanol solution, it is heated to reflux 2-3 times, it is spare obtains mixed solution B；
(5) it mixes：Mixed solution B in extracting solution A and step (4) in step (3) is added in blender together, It is stirred under the rotating speed of 600-800r/min, obtains mixed solution；
(6) it concentrates：Mixed solution low temperature in step (5) is concentrated into the 1/10 of original volume, is obtained in the present invention Drug composition；
(7) it packs：Obtained Chinese medicine composition in step (6) is packed；
It according to above-mentioned technical proposal, is sieved for 240-280 mesh used in the screening in the step (2), the step (5) is being stirred The time for mixing machine stirring is 15-25min, and the packing device of the step (7) is automatic packaging machine.
Embodiment 2：
A kind of Chinese medicine composition of Neurology treatment Parkinson, the Chinese medicine composition is to use multigroup Chinese medicine composition Raw material is prepared, and the quality proportioning of traditional Chinese medicine composite composition is：
5 parts of Radix Salviae Miltiorrhizae, 4 parts of honey-fried licorice root, 4 parts of radix scutellariae, 4 parts of Rhizoma Atractylodis Macrocephalae, 3 parts of Poria cocos, 3 parts of Radix Rehmanniae, 3 parts of radix rehmanniae preparata, 3 parts of asarum, Huang 3 parts of stilbene, 3 parts of earthworm, 4 parts of Rhizoma Chuanxiong, 3 parts of safflower, 4 parts of peach kernel, 3 parts of rhizoma typhonii, 4 parts of the larva of a silkworm with batrytis, 5 parts of scorpio, 3 parts of Radix Angelicae Pubescentis, when Return 4 parts, 3 parts of bark of ash, 3 parts of Rhizoma Et Radix Notopterygii, 4 parts of Herba Lycopodii, 5 parts of radix scrophulariae, 4 parts of raw sienna, 3 parts of Sagina subulata, 3 parts of oriental wormwood, arisaema cum bile 4 Part, 5 parts of korean pine seed, 3 parts of the fruit of Rangoon creeper, 3 parts of moutan bark, 6 parts of honeysuckle, 4 parts of stringy stonecrop, 3 parts of milk thistle, 3 parts of the root of fangji, calcined Dragon's bone 6 parts, 6 parts of calcined oyster shell, 6 parts of turtle shell.
According to above-mentioned technical proposal, the earthworm is earthworm powder, and the honeysuckle is dry for honeysuckle, and be by with adopt with It shines, honeysuckle is thinly sprinkled upon on pallet, pallet is placed in ventilation area without shade, Bei Gaonan is low, is divulged information with profit；It is dry to eighty per cant When, can stir and either close disk drying night or meet rain and pallet is placed within doors in time, avoid the discoloration that gets wet, fine day after Continuous drying, until drying；Drying：Kept when room temperature is increased to 40 DEG C or so general 6 it is small when, room temperature is maintained at 40~45 DEG C, Wait for that the aqueous vapor of fresh flower largely excludes, be such as not achieved 8 one-tenth it is dry more than, the time of 40~45 DEG C of temperature control need to be extended, then room temperature is carried To 55~60 DEG C, honeysuckle is dried rapidly；Entire drying course is manufactured after need to generally lasting 18 hours.
A kind of Chinese medicine composition preparation method of Neurology treatment Parkinson, includes the following steps：
(1) dispensing：Each raw material is weighed by formula, removal of impurities is dried rear spare；
(2) it crushes：By scorpio, Radix Angelicae Pubescentis, Radix Angelicae Sinensis, bark of ash, Rhizoma Et Radix Notopterygii, Herba Lycopodii, radix scrophulariae, raw sienna, Sagina subulata, oriental wormwood, courage After Southern Star, korean pine seed, the fruit of Rangoon creeper, moutan bark, honeysuckle, stringy stonecrop, milk thistle, the root of fangji, calcined Dragon's bone, calcined oyster shell and turtle shell crush Screening is crossed, obtains mixed-powder after mixing；
(3) extracting solution is prepared：Mixed-powder in step (2) is added to the water of 10-12 times of its total weight, be boiled by fire 3- Continue to decoct 20-30min after 5min, 4-6 times of water is added after filtering, decocts 20-30min, filters again, merges filtrate twice It is spare to obtain extracting solution A；
(4) mixed solution is prepared：By Radix Salviae Miltiorrhizae, honey-fried licorice root, radix scutellariae, Rhizoma Atractylodis Macrocephalae, Poria cocos, Radix Rehmanniae, radix rehmanniae preparata, asarum, Radix Astragali, Dragon, Rhizoma Chuanxiong, safflower, peach kernel, rhizoma typhonii, arisaema cum bile and the larva of a silkworm with batrytis are put into its 12-15 times of weight, volume fraction after mechanical crushing To impregnate 20-24h in 98% ethanol solution, it is heated to reflux 2-3 times, it is spare obtains mixed solution B；
(5) it mixes：Mixed solution B in extracting solution A and step (4) in step (3) is added in blender together, It is stirred under the rotating speed of 600-800r/min, obtains mixed solution；
(6) it concentrates：Mixed solution low temperature in step (5) is concentrated into the 1/10 of original volume, is obtained in the present invention Drug composition；
(7) it packs：Obtained Chinese medicine composition in step (6) is packed；
It according to above-mentioned technical proposal, is sieved for 240-280 mesh used in the screening in the step (2), the step (5) is being stirred The time for mixing machine stirring is 15-25min, and the packing device of the step (7) is automatic packaging machine.
Embodiment 3：
A kind of Chinese medicine composition of Neurology treatment Parkinson, the Chinese medicine composition is to use multigroup Chinese medicine composition Raw material is prepared, and the quality proportioning of traditional Chinese medicine composite composition is：
6 parts of Radix Salviae Miltiorrhizae, 5 parts of honey-fried licorice root, 5 parts of radix scutellariae, 5 parts of Rhizoma Atractylodis Macrocephalae, 4 parts of Poria cocos, 4 parts of Radix Rehmanniae, 4 parts of radix rehmanniae preparata, 4 parts of asarum, Huang 4 parts of stilbene, 4 parts of earthworm, 5 parts of Rhizoma Chuanxiong, 4 parts of safflower, 5 parts of peach kernel, 4 parts of rhizoma typhonii, 5 parts of the larva of a silkworm with batrytis, 6 parts of scorpio, 4 parts of Radix Angelicae Pubescentis, when Return 5 parts, 4 parts of bark of ash, 4 parts of Rhizoma Et Radix Notopterygii, 5 parts of Herba Lycopodii, 6 parts of radix scrophulariae, 5 parts of raw sienna, 4 parts of Sagina subulata, 4 parts of oriental wormwood, arisaema cum bile 5 Part, 6 parts of korean pine seed, 4 parts of the fruit of Rangoon creeper, 4 parts of moutan bark, 8 parts of honeysuckle, 5 parts of stringy stonecrop, 4 parts of milk thistle, 4 parts of the root of fangji, calcined Dragon's bone 10 parts, 10 parts of calcined oyster shell, 10 parts of turtle shell.
According to above-mentioned technical proposal, the earthworm is earthworm powder, and the honeysuckle is dry for honeysuckle, and be by with adopt with It shines, honeysuckle is thinly sprinkled upon on pallet, pallet is placed in ventilation area without shade, Bei Gaonan is low, is divulged information with profit；It is dry to eighty per cant When, can stir and either close disk drying night or meet rain and pallet is placed within doors in time, avoid the discoloration that gets wet, fine day after Continuous drying, until drying；Drying：Kept when room temperature is increased to 40 DEG C or so general 6 it is small when, room temperature is maintained at 40~45 DEG C, Wait for that the aqueous vapor of fresh flower largely excludes, be such as not achieved 8 one-tenth it is dry more than, the time of 40~45 DEG C of temperature control need to be extended, then room temperature is carried To 55~60 DEG C, honeysuckle is dried rapidly；Entire drying course is manufactured after need to generally lasting 18 hours.
A kind of Chinese medicine composition preparation method of Neurology treatment Parkinson, includes the following steps：
(1) dispensing：Each raw material is weighed by formula, removal of impurities is dried rear spare；
(2) it crushes：By scorpio, Radix Angelicae Pubescentis, Radix Angelicae Sinensis, bark of ash, Rhizoma Et Radix Notopterygii, Herba Lycopodii, radix scrophulariae, raw sienna, Sagina subulata, oriental wormwood, courage After Southern Star, korean pine seed, the fruit of Rangoon creeper, moutan bark, honeysuckle, stringy stonecrop, milk thistle, the root of fangji, calcined Dragon's bone, calcined oyster shell and turtle shell crush Screening is crossed, obtains mixed-powder after mixing；
(3) extracting solution is prepared：Mixed-powder in step (2) is added to the water of 10-12 times of its total weight, be boiled by fire 3- Continue to decoct 20-30min after 5min, 4-6 times of water is added after filtering, decocts 20-30min, filters again, merges filtrate twice It is spare to obtain extracting solution A；
(4) mixed solution is prepared：By Radix Salviae Miltiorrhizae, honey-fried licorice root, radix scutellariae, Rhizoma Atractylodis Macrocephalae, Poria cocos, Radix Rehmanniae, radix rehmanniae preparata, asarum, Radix Astragali, Dragon, Rhizoma Chuanxiong, safflower, peach kernel, rhizoma typhonii, arisaema cum bile and the larva of a silkworm with batrytis are put into its 12-15 times of weight, volume fraction after mechanical crushing To impregnate 20-24h in 98% ethanol solution, it is heated to reflux 2-3 times, it is spare obtains mixed solution B；
(5) it mixes：Mixed solution B in extracting solution A and step (4) in step (3) is added in blender together, It is stirred under the rotating speed of 600-800r/min, obtains mixed solution；
(6) it concentrates：Mixed solution low temperature in step (5) is concentrated into the 1/10 of original volume, is obtained in the present invention Drug composition；
(7) it packs：Obtained Chinese medicine composition in step (6) is packed；
It according to above-mentioned technical proposal, is sieved for 240-280 mesh used in the screening in the step (2), the step (5) is being stirred The time for mixing machine stirring is 15-25min, and the packing device of the step (7) is automatic packaging machine.
Based on above-mentioned, it is an advantage of the current invention that the present invention is all made of natural Chinese medicine material, selected medicinal material compatibility phase Preferably, meet traditional Chinese medicine and pharmacy and modern medical theory, to treatment Parkinson's disease tool by unique curative effect, manner of formulation is simple, absorbs Effect is good, have blood circulation promoting and enriching, medicine source is wide, at low cost, significant in efficacy, mild in medicine property and；It is without side-effects, it is safe.
The foregoing is merely illustrative of the preferred embodiments of the present invention, is not intended to limit the invention, all essences in the present invention All any modification, equivalent and improvement etc., should all be included in the protection scope of the present invention made by within refreshing and principle.

Claims (7)

1. a kind of Chinese medicine composition of Neurology treatment Parkinson, it is characterised in that：The Chinese medicine composition is using multigroup Traditional Chinese medicine composite is prepared, and the quality proportioning of traditional Chinese medicine composite composition is：
4-6 parts of Radix Salviae Miltiorrhizae, 3-5 parts of honey-fried licorice root, 3-5 parts of radix scutellariae, 3-5 parts of Rhizoma Atractylodis Macrocephalae, 2-4 parts of Poria cocos, 2-4 parts of Radix Rehmanniae, 2-4 parts of radix rehmanniae preparata, 2-4 parts of asarum, 2-4 parts of Radix Astragali, 2-4 parts of earthworm, 3-5 parts of Rhizoma Chuanxiong, 2-4 parts of safflower, 3-5 parts of peach kernel, 2-4 parts of rhizoma typhonii, white deadlock 3-5 parts of silkworm, 4-6 parts of scorpio, 2-4 parts of Radix Angelicae Pubescentis, 3-5 parts of Radix Angelicae Sinensis, 2-4 parts of bark of ash, 2-4 parts of Rhizoma Et Radix Notopterygii, 3-5 parts of Herba Lycopodii, radix scrophulariae 4-6 Part, 3-5 parts of raw sienna, 2-4 parts of Sagina subulata, 2-4 parts of oriental wormwood, 3-5 parts of arisaema cum bile, 4-6 parts of korean pine seed, 2-4 parts of the fruit of Rangoon creeper, tree peony 2-4 parts of skin, 4-8 parts of honeysuckle, 3-5 parts of stringy stonecrop, 2-4 parts of milk thistle, 2-4 parts of the root of fangji, 2-10 parts of calcined Dragon's bone, calcined oyster shell 2-10 Part, 2-10 parts of turtle shell.
2. the Chinese medicine composition of Neurology treatment Parkinson according to claim 1 a kind of, it is characterised in that：Describedly Dragon is earthworm powder.
3. the Chinese medicine composition of Neurology treatment Parkinson according to claim 1 a kind of, it is characterised in that：The gold Honeysuckle flower is dry for honeysuckle, and is by with adopting with solarization, honeysuckle is thinly sprinkled upon on pallet, and pallet, which is placed in ventilation, to face south Place, Bei Gaonan is low, is divulged information with profit；To eighty per cant it is dry when, can stir either close disk drying night or meet rain will be in time pallet It is placed within doors, the discoloration that gets wet, fine day is avoided to continue to dry, until drying；Drying：One is kept when room temperature is increased to 40 DEG C or so As 6 hours, room temperature is maintained at 40~45 DEG C, waits for that the aqueous vapor of fresh flower largely excludes, be such as not achieved 8 one-tenth it is dry more than, control need to be extended The time of 40~45 DEG C of temperature, then room temperature is mentioned 55~60 DEG C, honeysuckle is dried rapidly；Entire drying course need to generally last 18 Made of after hour.
4. a kind of Chinese medicine composition preparation method of Neurology treatment Parkinson, it is characterised in that：Include the following steps：
(1) dispensing：Each raw material is weighed by formula, removal of impurities is dried rear spare；
(2) it crushes：By scorpio, Radix Angelicae Pubescentis, Radix Angelicae Sinensis, bark of ash, Rhizoma Et Radix Notopterygii, Herba Lycopodii, radix scrophulariae, raw sienna, Sagina subulata, oriental wormwood, arisaema cum bile, Korean pine seed, the fruit of Rangoon creeper, moutan bark, honeysuckle, stringy stonecrop, milk thistle, the root of fangji, calcined Dragon's bone, calcined oyster shell and turtle shell grinding and sieving Choosing obtains mixed-powder after mixing；
(3) extracting solution is prepared：Mixed-powder in step (2) is added to the water of 10-12 times of its total weight, be boiled by fire 3-5min After continue to decoct 20-30min, 4-6 times of water is added after filtering, decocts 20-30min, filters again, filtrate obtains twice for merging Extracting solution A is spare；
(4) mixed solution is prepared：By Radix Salviae Miltiorrhizae, honey-fried licorice root, radix scutellariae, Rhizoma Atractylodis Macrocephalae, Poria cocos, Radix Rehmanniae, radix rehmanniae preparata, asarum, Radix Astragali, earthworm, river Rhizome of chuanxiong, safflower, peach kernel, rhizoma typhonii and the larva of a silkworm with batrytis are put into its 12-15 times of weight, the ethyl alcohol that volume fraction is 98% after mechanical crushing 20-24h is impregnated in solution, is heated to reflux 2-3 times, and it is spare to obtain mixed solution B；
(5) it mixes：Mixed solution B in extracting solution A and step (4) in step (3) is added in blender together, It is stirred under the rotating speed of 600-800r/min, obtains mixed solution；
(6) it concentrates：Mixed solution low temperature in step (5) is concentrated into the 1/10 of original volume, obtains the Chinese medicine group of the present invention Close object；
(7) it packs：Obtained Chinese medicine composition in step (6) is packed.
5. the Chinese medicine composition preparation method of Neurology treatment Parkinson according to claim 4 a kind of, feature exist In：Screening in the step (2) is used for 240-280 mesh sieve.
6. the Chinese medicine composition preparation method of Neurology treatment Parkinson according to claim 4 a kind of, feature exist In：The time that the step (5) is stirred in blender is 15-25min.
7. the Chinese medicine composition preparation method of Neurology treatment Parkinson according to claim 4 a kind of, feature exist In：The packing device of the step (7) is automatic packaging machine.
CN201710329194.3A 2017-05-11 2017-05-11 A kind of Chinese medicine composition of Neurology treatment Parkinson Pending CN108434281A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201710329194.3A CN108434281A (en) 2017-05-11 2017-05-11 A kind of Chinese medicine composition of Neurology treatment Parkinson

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201710329194.3A CN108434281A (en) 2017-05-11 2017-05-11 A kind of Chinese medicine composition of Neurology treatment Parkinson

Publications (1)

Publication Number Publication Date
CN108434281A true CN108434281A (en) 2018-08-24

Family

ID=63190844

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201710329194.3A Pending CN108434281A (en) 2017-05-11 2017-05-11 A kind of Chinese medicine composition of Neurology treatment Parkinson

Country Status (1)

Country Link
CN (1) CN108434281A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108743822A (en) * 2018-09-04 2018-11-06 刘露 A kind of Chinese medicine oil for treating Parkinson's disease

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104352725A (en) * 2014-10-17 2015-02-18 詹霞 Traditional Chinese medicinal composition for treating Parkinson's disease
CN105770611A (en) * 2016-05-03 2016-07-20 邵琳 Traditional Chinese medicine composition for neurologically treating Parkinson's disease
WO2016166565A1 (en) * 2015-04-13 2016-10-20 Ethnodyne Use of a withania extract for the treatment of alpha synucleinopathies

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104352725A (en) * 2014-10-17 2015-02-18 詹霞 Traditional Chinese medicinal composition for treating Parkinson's disease
WO2016166565A1 (en) * 2015-04-13 2016-10-20 Ethnodyne Use of a withania extract for the treatment of alpha synucleinopathies
CN105770611A (en) * 2016-05-03 2016-07-20 邵琳 Traditional Chinese medicine composition for neurologically treating Parkinson's disease

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108743822A (en) * 2018-09-04 2018-11-06 刘露 A kind of Chinese medicine oil for treating Parkinson's disease

Similar Documents

Publication Publication Date Title
CN106177754A (en) A kind of prevention, treatment sow and the compositions of mammitis of cow
CN103736037A (en) Medicine for treating chronic fatigue syndrome and preparation method thereof
CN105996637A (en) Combined Chinese herb healthcare pillow
CN102847061B (en) Traditional Chinese medicine preparation for treating pediatric viral myocarditis and preparation method thereof
CN102988639B (en) Medicament for treating cervical spondylosis and preparation method of medicament
CN104998061A (en) Traditional Chinese medicine formula for treating cold uterus and infertility and preparation method thereof
CN103656121A (en) Immunity-improving traditional Chinese medicine composition and preparation method thereof
CN104173957A (en) Anti-senile life-prolonging plaster
CN108434281A (en) A kind of Chinese medicine composition of Neurology treatment Parkinson
CN105106916A (en) Postpartum nursing traditional Chinese medicine
CN103520631B (en) Traditional Chinese medicine used for treating irregular menstruation
CN103417836B (en) Chinese medicine composition for the treatment of tumor and preparation method thereof
CN103157003B (en) Preparation method of pumpkin-fermented medicated wine as well as product and use of pumpkin-fermented medicated wine
CN106389720A (en) Medicine for treating ankylosing spondylitis and preparation method thereof
CN105412830A (en) Medicine for treating acute icteric hepatitis and preparation method thereof
CN104940719A (en) Spleen and kidney tonifying pill for relieving uremia and preparation method of spleen and kidney tonifying pill
CN105456928A (en) Drug for treating rheumatoid arthritis and preparation method thereof
CN105079354A (en) Traditional Chinese medicinal liquor for relaxing channels and relieving pain
CN104707003B (en) The Chinese medicinal capsule for the treatment of hypertension, hyperlipidemia
CN104922595A (en) Traditional Chinese medicinal preparation for herpes zoster and preparation method thereof
CN105029982B (en) Making method of health-care pillow cushion capable of treating cervical spondylosis and pillow cushion raw material formula thereof
CN103735833A (en) Medicament for treating alopecia of children and preparation method for medicament
CN104547970A (en) Health traditional Chinese medicine for reducing blood pressure, promoting blood circulation and realizing high immunity and making method of health traditional Chinese medicine
CN107744561A (en) A kind of Chinese herbal medicine formula lavipeditum powder and preparation method thereof
CN111346209A (en) Traditional Chinese medicine foot bath bag and preparation method thereof

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
WD01 Invention patent application deemed withdrawn after publication
WD01 Invention patent application deemed withdrawn after publication

Application publication date: 20180824