CN108434074A - A kind of tooth whitening composition itself - Google Patents

A kind of tooth whitening composition itself Download PDF

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Publication number
CN108434074A
CN108434074A CN201810382430.2A CN201810382430A CN108434074A CN 108434074 A CN108434074 A CN 108434074A CN 201810382430 A CN201810382430 A CN 201810382430A CN 108434074 A CN108434074 A CN 108434074A
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CN
China
Prior art keywords
whitening
stabilizer
parts
composition itself
tooth
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201810382430.2A
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Chinese (zh)
Inventor
谢海青
谢君毅
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Foshan University
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Foshan University
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Publication date
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Priority to CN201810382430.2A priority Critical patent/CN108434074A/en
Publication of CN108434074A publication Critical patent/CN108434074A/en
Pending legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/35Ketones, e.g. benzophenone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/23Sulfur; Selenium; Tellurium; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/63Steroids; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/66Enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/736Chitin; Chitosan; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/98Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
    • A61K8/987Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Emergency Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Zoology (AREA)
  • Cosmetics (AREA)

Abstract

The present invention provides a kind of tooth whitening composition itself, and the tooth whitening composition itself and its parts by weight include:20~50 parts of whitening agent, 5~15 parts of whitening catalyst, 15~30 parts of anti-sensitizer, 12~16 parts of stabilizer, 5~10 parts of preservative, surplus are deionized water;The whitening agent includes xylanase, pearl powder, bioactive minerals powder, sodium sulfite and Hydros, ratio 1:1:2:1:1;The whitening catalyst is one or more in rare earth oxide, rare earth chloride, rare earth compounding;The anti-sensitizer includes Paeonol and dipotassium glycyrrhizinate, ratio 2:1;The stabilizer includes whitening stabilizer and beneficial bacteria stabilizer, and the ratio of the whitening stabilizer and beneficial bacteria stabilizer is 1:1;The preservative includes sodium benzoate and ethylparaben;Its ratio is 1:1.1.The tooth whitening composition itself can effectively tooth-whitening, but larger stimulation will not be caused to tooth simultaneously.

Description

A kind of tooth whitening composition itself
Technical field
The present invention relates to oral care techniques field more particularly to a kind of tooth whitening composition itselfs.
Background technology
Pure white beautiful tooth is always a kind of fashion that people pursue.In today of the U.S. for advocating smiles in bloom, tooth Bright clean have become international fashion world and weigh beautiful mark.But due to various reasons, dental surface coloring greatly affected It is beautiful.Therefore tooth whitening is a very important thing.
The brightening agent in brightener for tooth is usually peroxide at present, and it is higher to add concentration.The presence of peroxide Two major classes can be divided into, one kind is that peroxide exists in liquid form, if the peroxide of liquid directly acts on tooth, counterpart It is less safe for chamber, and liquid peroxide compound itself is unstable, since the release of oxygen is not easy to maintain;Another kind of is peroxidating Object exists by solid form, and property is stablized, but to make solid peroxides not oxygen loss when making lotion, it is necessary in acid Property medium in, be allowed to fully dissolve, therefore the sensibility of tooth can be increased using such tooth whitening products for a long time.
Invention content
The present invention provides a kind of tooth whitening composition itself, the tooth whitening composition itself can effectively tooth-whitening, but Larger stimulation will not be caused to tooth simultaneously.
To achieve the above object, the present invention uses following technical proposals.
A kind of tooth whitening composition itself, which is characterized in that the tooth whitening composition itself and its parts by weight include:Whitening agent 20~50 parts, 5~15 parts of whitening catalyst, 15~30 parts of anti-sensitizer, 12~16 parts of stabilizer, 5~10 parts of preservative, surplus be Deionized water;
The whitening agent includes xylanase, pearl powder, bioactive minerals powder, sodium sulfite and Hydros, Ratio is 1:1:2:1:1;
The whitening catalyst is one or more in rare earth oxide, rare earth chloride, rare earth compounding;
The anti-sensitizer includes Paeonol and dipotassium glycyrrhizinate, ratio 2:1;
The stabilizer includes whitening stabilizer and beneficial bacteria stabilizer, the proportioning of the whitening stabilizer and beneficial bacteria stabilizer Ratio is 1:1;
The preservative includes sodium benzoate and ethylparaben;Its ratio is 1:1.1.
Further, the whitening stabilizer is self-adsorption type stabilizer, and the beneficial bacteria stabilizer is chitosan or sweet dew Glycan alcohol.
Further, the bioactivity miberal powder also has the ingredient of following weight percent:SiO220~25%, CaO 35~55%, TiO 5~10%, SrO 2~10%;Diameter of particle is 5~10 μm in the wherein described bioactivity miberal powder.
Further, the diameter of particle of the pearl powder is 30~60 μm.
Beneficial effects of the present invention are:In the present invention whitening agent include xylanase, pearl powder, bioactive minerals powder, Sodium sulfite and Hydros, xylanase are a kind of biological enzyme, carbohydrate or fibre in the tartar that can effectively degrade Dimension element, is allowed to loosen or fall off, and then both chemical whitening agents of sodium sulfite and Hydros is made to carry out deep reactions, with Reach the dosage of potent whitening function and reduction chemistry whitening agent;Bioactivity miberal powder has special inorganic amorphous structure, Possess and improves cell activity and promote the excellent properties such as biomineralization, and a large amount of calcium of pearl powder CNOOC and abundant micro- Secondary element and a variety of amino acid being easily absorbed by the body, bioactivity miberal powder and pearl powder synergistic effect pass through physics mode temperature Tartar and secured tooth are removed with ground;Rare earth compound be also added in the present invention as whitening catalyst, tartar can be made In coloring matter activation, reduce the activation energy of bleaching action, make reacting for tartar and whitening agent more depth, while rare earth chemical combination Object is also a kind of effective fungicide, acts synergistically with Paeonol and alleviates the condition susceptible of tooth.
Specific implementation mode
The technique effect of the design of the present invention, concrete structure and generation is carried out below with reference to embodiment clear, complete Ground describes, to be completely understood by the purpose of the present invention, feature and effect.Obviously, described embodiment is the one of the present invention Section Example, rather than whole embodiments, based on the embodiment of the present invention, those skilled in the art are not paying creativeness The other embodiment obtained under the premise of labour, belongs to the scope of protection of the invention.In addition, what is be previously mentioned in text is all / connection relation is connect, not singly refers to component and directly connects, and referring to can be according to specific implementation situation, by adding or reducing connection Auxiliary, to form more preferably coupling structure.Each technical characteristic in the invention, under the premise of not conflicting conflict It can be with combination of interactions.
Embodiment 1
A kind of tooth whitening composition itself, which is characterized in that the tooth whitening composition itself and its parts by weight include:Whitening agent 35 parts, 10 parts of whitening catalyst, 25 parts of anti-sensitizer, 13 parts of stabilizer, 6 parts of preservative, surplus be deionized water;
The whitening agent includes xylanase, pearl powder, bioactive minerals powder, sodium sulfite and Hydros, Ratio is 1:1:2:1:1;
The whitening catalyst is one or more in rare earth oxide, rare earth chloride, rare earth compounding;
The anti-sensitizer includes Paeonol and dipotassium glycyrrhizinate, ratio 2:1;
The stabilizer includes whitening stabilizer and beneficial bacteria stabilizer, the proportioning of the whitening stabilizer and beneficial bacteria stabilizer Ratio is 1:1;
The preservative includes sodium benzoate and ethylparaben;Its ratio is 1:1.1.
Further, the whitening stabilizer is self-adsorption type stabilizer, and the beneficial bacteria stabilizer is chitosan or sweet dew Glycan alcohol.
Further, the bioactivity miberal powder also has the ingredient of following weight percent:SiO2 25%, CaO55%, TiO 10%, SrO 10%;Diameter of particle is 5~10 μm in the wherein described bioactivity miberal powder.
Further, the diameter of particle of the pearl powder is 30~60 μm.
Tooth whitening composition itself made from Example 1 carries out efficacy test.
Object on probation:Totally 100 people, the range of age are 20~50 years old.
Test method and observed content:For subject without disease, blood routine, blood platelet, clotting time are normal.By subject with Machine is grouped, and double blind pairing is divided into control group and experimental group.Case load is divided into control group and experimental group, each 50 people.Test group is tested Person brushes teeth 2 times sooner or later daily, every time using the tooth whitening composition itself described in embodiment 1, continues 6 months, is partly quivered using water Dynamic method is brushed teeth;Control group subject brushes teeth 2 times sooner or later daily, uses conventional dental lightening compositions every time, continues 6 months, adopt It is brushed teeth with half trembling method of water.
Curative effect judging standard:
It is effective:Subjective symptom is obviously improved, plaque index (PLI), gingival sulcus mountain blood index (SRT), gingival index (GI) value Drop-out value>1.
It improves:Symptom mitigates, gingival sulcus mountain blood improves, at least one decline in periodontal index.
In vain:Symptom slightly improves or unchanged.
As a result:Clinical examination in 6 months, wherein control group 3, test group 3
The comparison of 1 control group of table and test group periodontal index before the test
Subject Plaque index (PLI) Gingival sulcus bleeding index (SBI) Gingival index (GI)
50 people of control group 3±0.5 1.6±0.4 1.2±0.4
50 people of test group 3.1±0.6 1.55±0.4 1.16±0.3
It can be seen that two groups of subjects before the test through statistics examine by plaque index, gingival sulcus bleeding index, gingival index It tests, control group and test group there are no significant difference are comparable.
After table clinical examination in 26 months, the comparison of the periodontal index of test group and control group
Subject Plaque index (PLI) Gingival sulcus bleeding index (SBI) Gingival index (GI)
Test group (50 people) 1.35±0.2 0.75±0.5 1.34±0.3
Control group (50 people) 2.61±0.7 1.71±0.4 1.4±0.7
Dentistry lightening compositions 6 of the subject in test group in using the present embodiment 1 as can be seen from the above data There is highly significant sex differernce before plaque index, gingival sulcus bleeding index, gingival index and use after a month;And control group uses often There was no significant difference before with use after rule tooth whitening composition itself.
The better embodiment of the present invention is illustrated above, but the invention is not limited to the implementation Example, those skilled in the art can also make various equivalent modifications or be replaced under the premise of without prejudice to spirit of that invention It changes, these equivalent modifications or replacement are all contained in the application claim limited range.

Claims (4)

1. a kind of tooth whitening composition itself, which is characterized in that the tooth whitening composition itself and its parts by weight include:Whitening agent 20 ~50 parts, 5~15 parts of whitening catalyst, 15~30 parts of anti-sensitizer, 12~16 parts of stabilizer, 5~10 parts of preservative, surplus be go Ionized water;
The whitening agent includes xylanase, pearl powder, bioactive minerals powder, sodium sulfite and Hydros, proportioning Ratio is 1:1:2:1:1;
The whitening catalyst is one or more in rare earth oxide, rare earth chloride, rare earth compounding;
The anti-sensitizer includes Paeonol and dipotassium glycyrrhizinate, ratio 2:1;
The stabilizer includes whitening stabilizer and beneficial bacteria stabilizer, the ratio of the whitening stabilizer and beneficial bacteria stabilizer It is 1:1;
The preservative includes sodium benzoate and ethylparaben;Its ratio is 1:1.1.
2. a kind of tooth whitening composition itself according to claim 1, which is characterized in that the whitening stabilizer is from absorption Type stabilizer, the beneficial bacteria stabilizer are chitosan or mannosan alcohol.
3. a kind of tooth whitening composition itself according to claim 1, which is characterized in that the bioactivity miberal powder also have with The ingredient of lower weight percent:SiO220~25%, CaO 35~55%, TiO 5~10%, SrO 2~10%;Wherein institute It is 5~10 μm to state diameter of particle in bioactivity miberal powder.
4. a kind of tooth whitening composition itself according to claim 1, which is characterized in that the diameter of particle of the pearl powder is 30~60 μm.
CN201810382430.2A 2018-04-25 2018-04-25 A kind of tooth whitening composition itself Pending CN108434074A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201810382430.2A CN108434074A (en) 2018-04-25 2018-04-25 A kind of tooth whitening composition itself

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Application Number Priority Date Filing Date Title
CN201810382430.2A CN108434074A (en) 2018-04-25 2018-04-25 A kind of tooth whitening composition itself

Publications (1)

Publication Number Publication Date
CN108434074A true CN108434074A (en) 2018-08-24

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20230210732A1 (en) * 2022-01-04 2023-07-06 Cao Group, Inc. Reductive teeth whitening utilizing salts of dithionite

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107028799A (en) * 2017-02-21 2017-08-11 广州薇美姿实业有限公司 A kind of oral cavity baste of antiallergic whitening
CN107753325A (en) * 2017-10-31 2018-03-06 吉林省亨泰服装洗染科学技术研究所 A kind of whitening promoting and tooth-building toothpaste and preparation method thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107028799A (en) * 2017-02-21 2017-08-11 广州薇美姿实业有限公司 A kind of oral cavity baste of antiallergic whitening
CN107753325A (en) * 2017-10-31 2018-03-06 吉林省亨泰服装洗染科学技术研究所 A kind of whitening promoting and tooth-building toothpaste and preparation method thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20230210732A1 (en) * 2022-01-04 2023-07-06 Cao Group, Inc. Reductive teeth whitening utilizing salts of dithionite

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Application publication date: 20180824