CN108420464A - Sampling device for biopsy - Google Patents

Sampling device for biopsy Download PDF

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Publication number
CN108420464A
CN108420464A CN201810254540.0A CN201810254540A CN108420464A CN 108420464 A CN108420464 A CN 108420464A CN 201810254540 A CN201810254540 A CN 201810254540A CN 108420464 A CN108420464 A CN 108420464A
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CN
China
Prior art keywords
sampling
syringe needle
biopsy
tube
fixed part
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201810254540.0A
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Chinese (zh)
Inventor
沈靖南
尹军强
黄纲
邹昌业
谢显彪
王永谦
王博
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First Affiliated Hospital of Sun Yat Sen University
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First Affiliated Hospital of Sun Yat Sen University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by First Affiliated Hospital of Sun Yat Sen University filed Critical First Affiliated Hospital of Sun Yat Sen University
Priority to CN201810254540.0A priority Critical patent/CN108420464A/en
Publication of CN108420464A publication Critical patent/CN108420464A/en
Pending legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/02Instruments for taking cell samples or for biopsy
    • A61B10/0233Pointed or sharp biopsy instruments
    • A61B10/0266Pointed or sharp biopsy instruments means for severing sample
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M19/00Local anaesthesia; Hypothermia

Abstract

The invention discloses a kind of sampling device for biopsy.The sampling device for biopsy is particularly suitable for adjoining the biopsy sampling of the tissues such as important blood vessels, nerve around the small sizes tumours such as Bone and soft tissue tumors and/or tumour, can solve the problems, such as the biopsy that puncture procedure spatial dimension is small, needs precise positioning.Wherein guid needle can be connect by needle stand with syringe, is carried out local anaesthesia and Fluoroscopy location work, can be reduced surgical operation step, mitigate the pain of patient;And since guid needle only serves the effect of guiding or injection, therefore it can accomplish that diameter is very small, so as to increase in the operable space on tumour periphery, advantageously reduce the operation difficulty punctured repeatedly, and advantageously reduce damage to tissue, and under the guiding of syringe needle tube, outer tube can effectively avoid the important histoorgan in periphery when being inserted into body with sampling inner core, reduce the risk of puncture.The sampling device for biopsy combines minimally invasive guiding and anesthesia guiding, is conducive to shorten surgical procedure.

Description

Sampling device for biopsy
Technical field
The present invention relates to medical instruments fields, more particularly, to a kind of sampling device for biopsy.
Background technology
Bone and soft tissue tumors are occupied an important position in orthopaedics, and diagnosing and treating is always the difficult point of orthopaedics.Clinically, Bone tissue biopsy inspection is to diagnose the important means of a variety of orthopaedic diseases, and biopsy needle is required in bone tissue biopsy procedure Instrument, but the biopsy needle applied at present can only meet the needs that routine clinical bone tissue punctures, it is difficult to meet some particular fields The use demand of conjunction, as the biopsy of some Bone and soft tissue tumors samples occasion.
Clinical some common Bone and soft tissue tumors small volumes (tumour maximum diameter only 2-5cm), it is more difficult to it positions, and Often adjoin the histoorgans such as important blood vessels, nerve, spinal cord around tumor tissues, assisted even if being navigated using coherent video, Also due to the operable space in tumour periphery is limited, need to puncture repeatedly.And traditional bone tissue puncture gauge 8-15G it Between (internal diameter is all higher than 1.3mm), it is repeated multiple times puncture be easy to cause operating time extension, and can cause damaging surrounding tissue to suffer from Person causes unnecessary pain, and while damaging serious can lead to the hair of the medical complications such as peripheral vessels, nerve, spinal cord injury It is raw.
It is traditional there are also improved biopsy needle, as being not easily taken out for Bone and soft tissue tumors etc. the problem of carries out It improves, is for another example directed to the improvement etc. of orientation problem when aspiration biopsy, but traditional biopsy needle still remains Needle localization precision It is not high, and the problem of easily cause tissue damage.
Invention content
Based on this, it is necessary to provide a kind of biopsy sampling that can be improved positioning accuracy and tissue damage problem can be reduced Device.
A kind of sampling device for biopsy, including:
Guid needle, the guid needle include needle stand and the syringe needle tube that is connect with the needle stand, the needle stand and the syringe needle Pipe is separable, and the syringe needle tube is for puncturing to target tissue site;
Outer tube, the outer tube include housing fixed part and Casing-Cutting portion, and the housing fixed part is connected to institute The one end in Casing-Cutting portion is stated, the housing fixed part is external for staying in, and the other end in the Casing-Cutting portion has cutting Head, the Casing-Cutting portion can be sleeved on the syringe needle tube and can be cut into along the syringe needle tube by the cutting head Enter the target tissue site;And
Inner core is sampled, the sampling inner core includes sampling fixed part and drive pipe portion, the sampling fixed part connection One end in the drive pipe portion, the sampling fixed part can be limited with the housing fixed part to be coordinated, the sampling set There is the other end of pipe portion sampling head, the drive pipe portion to be used to be inserted into the Casing-Cutting portion and can be along the cutting Cannula portion and/or the syringe needle tube are inserted into sampling point;
The length of the syringe needle tube is more than the length of the outer tube.
The internal diameter of the syringe needle tube is 0.06mm~0.16mm in one of the embodiments,.
The length of the syringe needle tube is more than the length of the sampling inner core, the sampling set in one of the embodiments, The length of pipe portion is more than the length in the Casing-Cutting portion.
The needle stand is equipped with cyclic annular, single-blade shape or double-vane shape pintle in one of the embodiments,.
Pipe, insert-type sleeve-connected are connected through a screw thread between the needle stand and the syringe needle tube in one of the embodiments, Pipe, pre-break formula connecting tube or can shear-type connecting tube connection.
The sampling inner core further includes handle portion in one of the embodiments, and the handle portion is fixed with the sampling Portion connects.
The housing fixed part is equipped with the stair-stepping limit being connected to the Casing-Cutting portion in one of the embodiments, Position hole, the sampling fixed part are annular stepped structure compatible with the limit hole.
The cutting head has sharp edge ring in one of the embodiments, and the sharp edge ring is by multiple semicircle swords Mouth cyclization is constituted or is made of multiple cutting edges in the arrangement of worm gear shape;
The shape of the sampling head is beveled tip head, strip forming head, multi-edge column-shaped tip, hook tip or worm gear shape tip.
It is equipped in the syringe needle tube, the Casing-Cutting portion and the drive pipe portion in one of the embodiments, Scale marker.
The sampling device for biopsy further includes needle fixture in one of the embodiments, and the syringe needle fixes dress It sets including crossbeam, syringe needle lock-screw, supporting rod, support castor and castor lock screw, the crossbeam is equipped with for institute The mounting hole that syringe needle tube passes through is stated, one end of the syringe needle lock-screw can screw in the mounting hole and be contacted with the syringe needle tube Being locked the syringe needle tube in the mounting hole, the crossbeam is respectively provided with tooth mouth in the both sides of the mounting hole, The supporting rod has two, and two supporting rods can be each passed through two tooth mouths and be engaged with the crossbeam and two branch The distance between strut is adjustable, and the support castor is ellipse and there is rubber face, the support castor to be located at described for side The both ends of supporting rod, the castor lock screw is for being locked the support leg wheel in the end of the supporting rod.
The sampling device for biopsy of the present invention is particularly suitable for adjoining around the small sizes tumours such as Bone and soft tissue tumors and/or tumour The biopsy of the tissues such as adjacent important blood vessels, nerve samples, and can solve the live body group that puncture procedure spatial dimension is small, needs precise positioning The problem of knitting inspection.On the whole, sampling device for biopsy of the invention has at least the following advantages:
It after 1. guid needle is inserted into target tissue site, can be connect with syringe by needle stand, carry out local anaesthesia and perspective Work is positioned, other invasive anesthesia surgeries is not necessarily to, surgical operation step can be reduced, mitigate the pain of patient;
2. since guid needle only serves the effect of guiding or injection, it can accomplish that diameter is very small, so as to increase The operable space on tumour periphery, advantageously reduces the operation difficulty punctured repeatedly, especially is needing to carry out positional operand repeatedly When making, since the diameter of guid needle can be much smaller than traditional bone tissue puncture needle, the pain of patient in surgical procedure can be reduced Hardship, and it is small to the damage of surrounding tissue, be conducive to the postoperative reparation of patient;
3. the needle stand of guid needle is separable with syringe needle tube, thus needle stand is divided with the syringe needle tube for being inserted in target tissue site From rear, directly outer tube and/or sampling the inner core target tissue site that goes directly can be guided to be sampled using syringe needle tube, in syringe needle tube Guiding under, outer tube with sampling inner core be inserted into body when can effectively avoid the important histoorgan in periphery, reduce puncture Risk;
4. the sampling device for biopsy of the present invention, combines above-mentioned advantage, sampling process is safe and easy to operate, more can be from The successful probability of biopsy is improved on the whole, can disposably be completed puncturing operation, be avoided puncturing repeatedly;
5. the sampling device for biopsy of the present invention combines minimally invasive guiding and anesthesia guiding, is conducive to shorten surgical procedure, subtract The radiation that few perspective or CT positioning generate damages patient and medical staff.
Description of the drawings
Fig. 1 is the structural schematic diagram of the sampling device for biopsy of an embodiment of the present invention;
Fig. 2 a, 2b and Fig. 2 c are respectively the structural representation of the guid needle of cyclic annular pintle, single-blade shape pintle and double-vane shape pintle Figure;
Fig. 3 a, 3b and 3c are respectively that needle stand and syringe needle tube pass through pre-break formula connecting tube, insert-type sleeve-connected pipe and screw thread The connection relationship diagram of connecting tube;
Fig. 4 is the structural schematic diagram of outer tube in Fig. 1;
Fig. 5 a and 5b are respectively front view and the side view for the cutting head of outer tube being made of multiple semicircle cutting edge cyclization Figure, Fig. 5 c are the structural schematic diagram for the cutting head being made of multiple cutting edges in the arrangement of worm gear shape;
Fig. 6 is the structural schematic diagram that inner core is sampled in Fig. 1;
Fig. 7 a, 7b, 7c, 7d and 7e are respectively the beveled tip head shapes, strip head shapes, multi-edge column-shaped tip for sampling inner core The structural schematic diagram of the sampling head of shape, hook pointed shape and worm gear shape pointed shape;
Fig. 8 is the cooperation schematic diagram of the guid needle and outer tube in Fig. 1;
Fig. 9 is the cooperation schematic diagram of outer tube and sampling inner core in Fig. 1;
Figure 10 is the cooperation schematic diagram of guid needle, outer tube and needle fixture in Fig. 1;
Figure 11 a, 11b, 11c and 11d are respectively the vertical view of needle fixture in Figure 10, support castor schematic diagram, cross The vertical view of beam and the side view of crossbeam;
Figure 12 is bone tumour volunteer's image picture in embodiment 1.
Specific implementation mode
To facilitate the understanding of the present invention, below with reference to relevant drawings to invention is more fully described.In attached drawing Give presently preferred embodiments of the present invention.But the present invention can realize in many different forms, however it is not limited to this paper institutes The embodiment of description.Keep the understanding to the disclosure more thorough on the contrary, purpose of providing these embodiments is Comprehensively.
It should be noted that when element is referred to as " being fixed on " another element, it can be directly on another element Or there may also be elements placed in the middle.When an element is considered as " connection " another element, it can be directly connected to To another element or it may be simultaneously present centering elements.
Unless otherwise defined, all of technologies and scientific terms used here by the article and belong to the technical field of the present invention The normally understood meaning of technical staff is identical.Used term is intended merely to description tool in the description of the invention herein The purpose of the embodiment of body, it is not intended that in the limitation present invention.Term as used herein "and/or" includes one or more phases Any and all combinations of the Listed Items of pass.
As shown in Figure 1, the sampling device for biopsy 10 of an embodiment includes in guid needle 100, outer tube 200 and sampling Core 300.Guid needle 100 is mainly used as drug injection and when outer tube 200 and/or sampling inner core 300 are inserted into as guiding.Outside Casing 200 is used to match with sampling inner core 300 and is cut into target tissue site and is sampled.
Specifically, Fig. 2 a please be join, guid needle 100 is hollow structure, including needle stand 110 and the syringe needle that is connect with needle stand 110 Pipe 120.Needle stand 110 is separable with syringe needle tube 120, and syringe needle tube 120 is for puncturing to target tissue site.
In the present embodiment, needle stand 110 has for the pintle with the mating connection of the external injection device such as syringe 112a.The pintle 112a of guid needle 100 as shown in Figure 2 a is annular in shape.In other embodiments, pintle as shown in Figure 2 b Pintle 112c shown in 112b and Fig. 2 c is respectively single-blade shape and double-vane shape.The pintle of single-blade shape and double-vane shape is conveniently operated, such as It is pierced into convenient for guid needle 100, connection syringe, punctures repeatedly and the operations such as be detached from syringe needle tube 120, while being also easy to fix, Patient can be reduced and deviate (biopsy is usually local anaesthesia) caused by the slight vibrations such as twitch.Pintle on needle stand 110 is excellent It is selected as the pintle of single-blade shape.
The needle stand 110 of present embodiment is detachable connection with syringe needle tube 120.Specifically, such as Fig. 3 a, Fig. 3 b and Fig. 3 c It is shown, pre-break formula connecting tube, insert-type sleeve-connected pipe and screw nipple etc. can be passed through between needle stand 110 and syringe needle tube 120 Mode connects.Wherein, pre- folding connecting tube, that is, connecting tube is equipped with the pre- folding line convenient for fractureing;Insert-type sleeve-connected pipe, that is, needle stand In 110 pluggable syringe needle tubes 120 or syringe needle tube 120 can be inserted into needle stand 110;Screw nipple, that is, needle stand 110 and syringe needle tube 120 connect in end thread, such as can be located at external screw thread on needle stand 110, internal thread, Huo Zhe are arranged on syringe needle tube 120 Internal thread is set on needle stand 110, external screw thread etc. is set on syringe needle tube 120.Connecting tube between needle stand 110 and syringe needle tube 120 Material can be that stainless steel, aluminium alloy, magnesium alloy etc. may be used also between needle stand 110 and syringe needle tube 120 in other embodiments With using can the connection of shear-type connecting tube, medical polyvinyl (PVC), polyurethane (PU), polypropylene (PP), poly- such as may be used The plastic materials such as ethylene (PE) make, convenient for cutting.
In the present embodiment, can be done as the internal diameter of the syringe needle tube of guiding 120 it is very small, as internal diameter can be 0.16mm~0.06mm (30G~34G), in this way the bone tissue puncture needle compared with traditional specification between 8G~15G are being punctured When can reduce damage to tissue, reduce the pain of patient, even if needing to puncture repeatedly, repeatedly puncture to reduce as possible Damage to tissue, and since specification is smaller, it is possible to prevente effectively from the damage to sampling tissue surrounding tissue.
As shown in figure 4, outer tube 200 includes housing fixed part 210 and Casing-Cutting portion 220.Housing fixed part 210 connects It is connected on the one end in Casing-Cutting portion 220, housing fixed part 210 is external for staying in.The position hollow tubular knot in Casing-Cutting portion 220 Structure, the other end have cutting head 222.As shown in figure 8, Casing-Cutting portion 220 can be sleeved on syringe needle tube 120 and can pass through Cutting head 222 is cut into target tissue site along syringe needle tube 120.
Cutting head 222 has sharp edge ring.As shown in Fig. 5 a, 5b and 5c, sharp edge ring is by multiple semicircle cutting edge cyclization It constitutes or is made of multiple cutting edges in the arrangement of worm gear shape.Cutting head 222 by the sharp edge ring can with incised tissue, into Enter target tissue site.
As shown in fig. 6, sampling inner core 300 includes sampling fixed part 310 and drive pipe portion 320.Sample fixed part 310 It is connected to the one end in drive pipe portion 320, sampling fixed part 310 can be limited with housing fixed part 210 to be coordinated.Drive pipe portion 320 be hollow tubular structure.The other end in drive pipe portion 320 has sampling head 322, and drive pipe portion 320 is for being inserted into Casing-Cutting portion 220 simultaneously can be inserted into sampling point along Casing-Cutting portion 220 and/or syringe needle tube 120.
As shown in Fig. 7 a, 7b, 7c, 7d and 7e, the shape of sampling head 322 can be for beveled tip head, strip forming head, polygon prism The various shapes convenient for being pierced into and sampling such as shape tip, hook tip or worm gear shape tip, preferably strip forming head.
Incorporated by reference to Fig. 4, Fig. 6 and Fig. 9, in the present embodiment, housing fixed part 210 is equipped with to be connected with Casing-Cutting portion 220 Logical stair-stepping limit hole 212.Sampling fixed part 310 is annular stepped structure compatible with limit hole 212.Further, In the present embodiment, limit hole 212 is three-level stepped hole, and from one end far from Casing-Cutting portion 220 to Casing-Cutting portion One end internal diameter of 220 connections is gradually reduced, until consistent with the internal diameter in Casing-Cutting portion 220;Sampling fixed part 310 is two-stage ring Shape hierarchic structure can be adapted with the preceding two-stage hole of three-level stepped hole position.By the way that housing fixed part 210 is arranged and matches therewith The sampling fixed part 310 of set can fix sampling inner core 300 when obtaining tissue sample, avoid drive pipe portion 320 too deep It is pierced into, simultaneously because usually local anaesthesia when biopsy, uses housing fixed part 210 and the sampling fixed part to match therewith 310 can be shifted in drive pipe portion 320 to avoid patient caused by the slight vibrations such as twitch, and sampling deviation is caused.
Further, Fig. 6 please be join, the sampling inner core 300 of present embodiment further includes handle portion 330.Handle portion 330 and sampling Fixed part 310 connects.By the way that handle portion 330 is arranged, can also allow for taking out or being pierced into taking in order to rotate drive pipe portion 320 Sample cannula portion 320, and then conveniently tissue sample is obtained repeatedly.
In the present embodiment, the length of syringe needle tube 120 needs the length for being longer than outer tube 200, and to be preferably also longer than The length of inner core 300 is sampled, such as in one embodiment, the length of syringe needle tube 120 can be 8cm~40cm.Further preferably , the length in drive pipe portion 320 is more than the length in Casing-Cutting portion 220 and such as in one embodiment entirely samples inner core 300 length is 8cm~18cm.
Further, in the present embodiment, it is equipped in syringe needle tube 120, Casing-Cutting portion 220 and drive pipe portion 320 Scale marker is conducive to the depth that operator understands piercing in time in this way when being pierced into, convenient for the positioning for being pierced into and sampling.
In addition, as shown in Figure 10 and Figure 11 a~Figure 11 d, in the present embodiment, which further includes needle Head fixing device 400.Needle fixture 400 includes crossbeam 410, syringe needle lock-screw 420, supporting rod 430, support castor 440 and castor lock screw 450.Crossbeam 410 is equipped with the mounting hole 412 passed through for syringe needle tube 120.Syringe needle lock-screw 420 one end can screw in mounting hole 412 and be contacted with syringe needle tube 120 being locked syringe needle tube 120 in mounting hole 412. Crossbeam 410 is respectively provided with tooth mouth 414 in the both sides of mounting hole 412.Supporting rod 430 is arched, and which is provided with being capable of groove.Support Bar 430 has two, and two supporting rods 430 can be each passed through two tooth mouths 414 and be engaged with crossbeam 410 and two supporting rods 430 The distance between it is adjustable.Supporting castor 440 to be oval and side has rubber face, and the rubber face is for being placed on supporter On.Support castor 440 is located at the both ends of supporting rod 430.Castor lock screw 450 will be for that will support castor 440 to be locked On supporting rod 430.
The sampling device for biopsy 10 of present embodiment is particularly suitable for the small sizes such as Bone and soft tissue tumors tumour and/or tumour Around adjoin the biopsy samplings of the tissues such as important blood vessels, nerve, can solve that puncture procedure spatial dimension is small, needs precise positioning The problem of biopsy.Wherein, after guid needle 100 is inserted into target tissue site, can be connected by needle stand 110 and syringe It connects, carries out local anaesthesia and Fluoroscopy location work, be not necessarily to other invasive anesthesia surgeries, surgical operation step can be reduced, mitigate disease The pain of people;And since guid needle 100 only serves the effect of guiding or injection, guid needle 100 is not used as sampling, therefore, can To accomplish that diameter is very small, so as to increase in the operable space on tumour periphery, the operation punctured repeatedly is advantageously reduced Difficulty, especially when needing to carry out positioning operation repeatedly, since the diameter of guid needle 100 can be much smaller than traditional bone tissue Puncture needle can reduce the pain of patient in surgical procedure, and small to the damage of surrounding tissue, be conducive to the postoperative reparation of patient; The syringe needle tube 120 of guid needle 100 directly can guide outer tube 200 using syringe needle tube 120 and/or take after being detached with needle stand 110 The target tissue site that goes directly of sample inner core 300 is sampled, under the guiding of syringe needle tube 120, in outer tube 200 and sampling inner core The important histoorgan in periphery can be effectively avoided when 300 insertion body, reduces the risk of puncture.
The structure and application method of the sampling device for biopsy of the present invention are made into one below in conjunction with two specific embodiments Step detailed description.
Embodiment 1
The sampling device for biopsy of the Bone and soft tissue tumors of the present embodiment includes guid needle, sampling inner core and outer tube.It leads Draw pin is made of syringe needle tube and needle stand, syringe needle tube model 32G (internal diameter 0.11mm), length 35cm, and needle stand uses single-blade The needle stand of shape pintle, syringe needle tube and needle stand are connected by plastics transfer tube.The drive pipe size portion for sampling inner core is strip, long Degree is 12cm, model 27G (internal diameter 0.21mm).Casing-Cutting minister's degree of outer tube is 10cm, model 20G (internal diameters For 0.60mm).
Application method:Existing bone tumour volunteer, tumor tissues are as shown in figure 12, and feature is positioned at 2 centrum (upper cervical of neck Vertebra), gross tumor volume it is small, only 3cm*2cm*2cm, and lesion locations are close to the vital tissues organ such as neck marrow, vertebral artery, oesophagus.Often Puncture needle is advised into fashionable, to avoid damage to neck marrow, vertebral artery, oesophagus etc., operable space is minimum, and even if being punctured, often It needs to adjust puncture angle according to perspective or CT images into 3cm, the puncture time is long, and can cause around caused by puncturing repeatedly The big consequence of tissue damage, wound.When carrying out biopsy to it using the sampling device for biopsy of the present embodiment, had an X-rayed using guid needle Lower positioning, after sharp property gos deep into lesion bone tissue, connection syringe carries out local infiltration anesthesia.Wait for anesthesia of patient position without sense of touch Afterwards, plastics transfer tube is cut.The syringe needle tube of guid needle is inserted in Casing-Cutting portion.When to prevent Casing-Cutting portion from entering human body The position offset for causing syringe needle tube with the frictional force of syringe needle tube fixes the syringe needle tube of guid needle using needle fixture, specifically It is:Syringe needle lock-screw is unscrewed, mounting hole is inserted in from syringe needle tube tail portion, screws syringe needle lock-screw;It is inserted on the tooth mouth of crossbeam Enter supporting rod and adjusts its position and spacing, it is fixed;Castor lock screw is unscrewed, the support castor for adjusting ellipse (carries rubber Glue rubbing surface) position, after entire needle fixture stabilization after, screw castor lock screw.Made with the syringe needle tube of guid needle For guiding, the sharp edge ring in Casing-Cutting portion is cut into tumor locus, extracts the syringe needle tube of guid needle out, removes syringe needle and fixes dress It sets.It is inserted into sampling inner core, until after sampling fixed part coincide with housing fixed part, the handle portion of 360 ° of rotation sampling inner cores waits swelling After tumor tissue is kept completely separate, sampling inner core is extracted, the biopsy procedure of bone tumour is completed.
Embodiment 2
The sampling device for biopsy of the Bone and soft tissue tumors of the present embodiment includes guid needle, sampling inner core and outer tube.It leads Draw pin is made of syringe needle tube and needle stand, syringe needle tube model 34G (internal diameter 0.06mm), length 15cm, and needle stand uses double-vane The needle stand of shape pintle, syringe needle tube and needle stand are connected by stainless steel pre-break formula connecting tube.Sample the drive pipe size portion of inner core For beveled tip head, length 14cm, model 32G (internal diameter 0.11mm).Casing-Cutting minister's degree of outer tube is 10cm, model For 18G (internal diameter 0.84mm).
Application method:Existing fibrosarcoma volunteer, tumor tissues are located at left upper arm, and feature is that gross tumor volume is small, size For 3cm*2cm*4cm, and nerve and blood vessel are adjoined in obscure boundary, periphery.The deficiency that conventional puncture needle is described in addition to embodiment 1 Outside, can also be larger due to diameter itself, peripheral soft tissues sliding can be pulled into fashionable, is caused suffering to patient, and lead to itself It is difficult to fix.When carrying out biopsy to it using the sampling device for biopsy of the present embodiment, using being positioned under guid needle CT, sharp property is goed deep into After lesion bone tissue, connection syringe carries out local infiltration anesthesia.After anesthesia of patient position is without sense of touch, connected from pre-break formula It is cut at the pre- folding line of pipe.Sampling inner core is inserted into outer tube, until after sampling fixed part coincide with housing fixed part, with guiding The syringe needle tube of needle drives outer tube and sampling inner core to be pierced into tumor locus as guiding, the tip in drive pipe portion, it is possible to reduce To the drawing of perienchyma, guid needle is extracted out, the handle portion of 360 ° of rotation sampling inner cores is pulled out after tumor tissues are kept completely separate Go out and sample inner core, obtain tumor tissues repeatedly, until obtaining enough tumor tissues samples.
Each technical characteristic of embodiment described above can be combined arbitrarily, to keep description succinct, not to above-mentioned reality It applies all possible combination of each technical characteristic in example to be all described, as long as however, the combination of these technical characteristics is not deposited In contradiction, it is all considered to be the range of this specification record.
Several embodiments of the invention above described embodiment only expresses, the description thereof is more specific and detailed, but simultaneously It cannot therefore be construed as limiting the scope of the patent.It should be pointed out that coming for those of ordinary skill in the art It says, without departing from the inventive concept of the premise, various modifications and improvements can be made, these belong to the protection of the present invention Range.Therefore, the protection domain of patent of the present invention should be determined by the appended claims.

Claims (10)

1. a kind of sampling device for biopsy, which is characterized in that including:
Guid needle, the guid needle include needle stand and the syringe needle tube that is connect with the needle stand, and the needle stand can with the syringe needle tube Separation, the syringe needle tube is for puncturing to target tissue site;
Outer tube, the outer tube include housing fixed part and Casing-Cutting portion, and the housing fixed part is connected to described cut One end of cannula portion is cut, the housing fixed part is external for staying in, and the other end in the Casing-Cutting portion has cutting head, institute Stating Casing-Cutting portion can be sleeved on the syringe needle tube and can be cut into institute along the syringe needle tube by the cutting head State target tissue site;And
Inner core is sampled, the sampling inner core includes that sampling fixed part and drive pipe portion, the sampling fixed part are connected to institute The one end in drive pipe portion is stated, the sampling fixed part can be limited with the housing fixed part to be coordinated, the drive pipe portion The other end there is sampling head, the drive pipe portion is for being inserted into the Casing-Cutting portion and can be along the Casing-Cutting Portion and/or the syringe needle tube are inserted into sampling point;
The length of the syringe needle tube is more than the length of the outer tube.
2. sampling device for biopsy as described in claim 1, which is characterized in that the internal diameter of the syringe needle tube be 0.06mm~ 0.16mm。
3. sampling device for biopsy as described in claim 1, which is characterized in that the length of the syringe needle tube is more than in the sampling The length of core, the length in the drive pipe portion are more than the length in the Casing-Cutting portion.
4. sampling device for biopsy as described in claim 1, which is characterized in that the needle stand is equipped with cyclic annular, single-blade shape or double The pintle of wing.
5. sampling device for biopsy as described in claim 1, which is characterized in that pass through spiral shell between the needle stand and the syringe needle tube Line connecting tube, insert-type sleeve-connected pipe, pre-break formula connecting tube or can shear-type connecting tube connection.
6. sampling device for biopsy as described in claim 1, which is characterized in that the sampling inner core further includes handle portion, described Handle portion is connect with the sampling fixed part.
7. sampling device for biopsy as described in claim 1, which is characterized in that the housing fixed part is equipped with to be covered with the cutting The stair-stepping limit hole of pipe portion connection, the sampling fixed part are annular stepped structure compatible with the limit hole.
8. sampling device for biopsy as described in claim 1, which is characterized in that the cutting head has sharp edge ring, the cutting edge of a knife or a sword Sharp sword ring is made of multiple semicircle cutting edge cyclization or is made of multiple cutting edges in the arrangement of worm gear shape;
The shape of the sampling head is beveled tip head, strip forming head, multi-edge column-shaped tip, hook tip or worm gear shape tip.
9. sampling device for biopsy as described in claim 1, which is characterized in that the syringe needle tube, the Casing-Cutting portion and institute It states and is equipped with scale marker in drive pipe portion.
10. such as sampling device for biopsy according to any one of claims 1 to 9, which is characterized in that further include that syringe needle fixes dress It sets, the needle fixture includes crossbeam, syringe needle lock-screw, supporting rod, supports castor and castor lock screw, described Crossbeam is equipped with the mounting hole passed through for the syringe needle tube, and one end of the syringe needle lock-screw can screw in the mounting hole Contacted with the syringe needle tube being locked the syringe needle tube in the mounting hole, the crossbeam in the mounting hole two Side is respectively provided with tooth mouth, and the supporting rod has two, and two supporting rods can be each passed through two tooth mouths and the crossbeam It engages and the distance between two described supporting rods is adjustable, the support castor is ellipse and side has rubber face, described Support castor is located at the both ends of the supporting rod, and the castor lock screw is for being locked the support leg wheel described The end of supporting rod.
CN201810254540.0A 2018-03-26 2018-03-26 Sampling device for biopsy Pending CN108420464A (en)

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CN109820544A (en) * 2019-03-29 2019-05-31 中国医学科学院北京协和医院 A kind of Spinal Metastatic Tumors puncture channel and equipment
WO2020135726A1 (en) * 2018-12-28 2020-07-02 南京畅丰生物科技有限公司 Rotation prevention biopsy needle
CN111839596A (en) * 2020-06-12 2020-10-30 珠海市人民医院 Clamping type conveniently-folded multi-section sampling rod
CN113100887A (en) * 2021-04-06 2021-07-13 首都医科大学宣武医院 Three-stage puncture cannula assembly for trigeminal semilunar ganglion balloon compression

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020135726A1 (en) * 2018-12-28 2020-07-02 南京畅丰生物科技有限公司 Rotation prevention biopsy needle
CN109820544A (en) * 2019-03-29 2019-05-31 中国医学科学院北京协和医院 A kind of Spinal Metastatic Tumors puncture channel and equipment
CN111839596A (en) * 2020-06-12 2020-10-30 珠海市人民医院 Clamping type conveniently-folded multi-section sampling rod
CN113100887A (en) * 2021-04-06 2021-07-13 首都医科大学宣武医院 Three-stage puncture cannula assembly for trigeminal semilunar ganglion balloon compression

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