CN1084203A

CN1084203A - Water-based compressed gas aeerosol

Info

Publication number: CN1084203A
Application number: CN 93101565
Authority: CN
Inventors: M·J·瑞诺兹
Original assignee: Individual
Current assignee: Individual
Priority date: 1992-09-07
Filing date: 1993-02-25
Publication date: 1994-03-23
Also published as: AU2619992A; AU632263B2; GB9302538D0; GB2270698A

Abstract

The water base aerosol product of a kind of pressurized gas, it comprises:

One comprises valve and injector device, also comprises the aerosol canister of an intubate when needing; A kind of solution or suspension that forms in the water base solvent that is being mainly by activeconstituents in said jar; And a kind of pressure is at least the rare gas element as propellant of 620kPag (20 ℃).

Description

Water-based compressed gas aeerosol

The present invention relates to the water-based compressed gas aeerosol product and relate to the method and apparatus that is used to make this product, particularly relate to the aerosol product that a kind of needs spray the finely powdered product, but be not limited to this product.

For many years people just wish to have always a kind of not with an organic solvent or organic propellant, to human body nontoxicity and not environmentally hazardous aerosol product, yet this hope still fails to realize so far.Although it is believed that the water base aerosol product that the rare gas element of utilization compression sprays is the ideal product, but still fail to produce a kind of this series products so far, and also do not work out a kind of method and apparatus that is used to produce this series products with characteristics such as gratifying preparation effect, product stability, storage life and jet particle fineness.

For example, U.S. Patent No. 3,854,636(Conway) disclosed such fact, when utilizing nitrogen, nitrous oxide or carbonic acid gas as propellant, pressure descends significantly along with the injection of product, guarantee that all products can both eject even when beginning, utilize a kind of " height " (not limiting) to press from aerosol canister, above-mentioned situation is still like this, and such high pressure must have a low rate of release, to avoid the injection along with aerosol content, in injection undesirable too drastic variation takes place in nature.Conway suggestion in order to overcome above-mentioned problem, can add at least one additional throttle orifice in his valve body design of aerosol canister.

“Principles of Aerosol Technology”，Paul A。Sanders, 1990, Van Nostrand Reinhold Company PP28-33,60-62,88-90 and 161-163; " The Science and Technology of Aerosol Packaging ", John S.Sciarra and Leonard Stoller, 1974, John Wiley ﹠amp; Sons, PP136-141; And " Kirk Othmer Encyclopaedia of Chemical Technology ", vol.1, PP670-685; All these documents have all been narrated why in generation nineteen fifty and generation nineteen sixty, nitrogen is subjected to warm welcome so as the potential use meeting that is used for the pressurized gas propellant of aerosol canister, and this is because nitrogen has inexpensive, hypotoxicity, inertia and stable advantage.But owing to nitrogen almost completely is insoluble in the aerocolloidal liquid phase, so the use of nitrogen has been rejected basically.This insoluble feasible nitrogen of using uses the volume of the aerosol canister of liquefaction (for example hydro carbons, halocarbon class or halogenated hydrocarbon) gas injection agent as the volume of the aerosol canister of propellant greater than those, and, when running into unscheduled event jar is inverted so that it is when spraying, the gas of compression only can be ejected into to a certain degree, and remaining gas is not enough to all products are gushed out.Therefore, except those did not need to spray the purposes of fine powder, pressurized gas use had in every respect all been abandoned basically.

The other problems relevant with the particularly water base aerosol product of common aerosol product is air or oxygen and microorganism or the bacterium that is difficult to get rid of wherein, and these materials can cause the active constituent in the liquid phase, the degraded of sense of smell component or other components causes the shelf life of aerosol product unacceptably to shorten.Although require promptly to reduce the global emissions that those cause the gas of Greenhouse effect and the gas that damages the ozone layer (for example comprising hydro carbons, halocarbon class or halogenated hydrocarbon gas) consumingly people in recent years, but still dissatisfied known or available water-based compressed gas aeerosol product may have wide wide purposes, and these purposes comprise that product need be ejected into remote sterilant aerosol from those need be sprayed into mist with product up to those but do not need to spray the product of remote fragrance air freshener or perfume and so on.

Therefore an object of the present invention is to provide and a kind ofly can be used for the water base aerosol product of pressurized gas of wide wide-range and a kind of method and apparatus that is used to make this product is provided.

One aspect of the present invention provides a kind of pressurized gas water base aerosol product, and this product contains:

An aerosol canister, it comprises a valve and injector device, also comprises an intubate when needed;

A kind of activeconstituents in said jar is being mainly solution or the suspension in the water-based solvent; And

A kind of pressure is at least 620kPag(20 ℃) the rare gas element propellant.

The present invention also provides a kind of method that is used to make water base aerosol product on the other hand, and this method comprises:

Preparing a kind of being scattered in by activeconstituents mainly is solution or suspension in the water-based solvent;

The said solution of aequum or suspension are packed in the aerosol canister;

A valve and injector are installed on said jar; And

With rare gas element jar is pressurized to and is at least 620kPag(20 ℃) pressure, be enough to all solution or suspension are gushed out from aerosol canister.

Preferably used water is saturated with rare gas element earlier, and said rare gas element is selected from nitrogen, nitrous oxide or carbonic acid gas, preferably nitrogen.Preferably used water is handled to remove the oxygen that is dissolved in wherein through the rare gas element bubbling earlier.Best said group water solution or suspension are through filtering removing impurity, and preparation and can under appropriate condition.Preferably rare gas element charges under appropriate condition.

Best said solution or suspension also contain antioxidant (as xitix) and cosolvent or sanitas or germ-resistant alcohols (for example ethanol) except that containing activeconstituents.Preferably used jar is a kind of low can that is pressed with weld seam.Preferably used jar is that a kind of nominal volume is the jar of 670ml.The volume of best water base active ingredient solution or suspension is about 300ml, and is used for pressure to the rare gas element of jar pressurization greater than 690kPag, and preferably 840-1000kPag(20 ℃).Other nominal tank volume/active ingredient solution or suspension vol are: 550ml/245ml and 1,400ml/625ml(approximation).

What the present invention also provided a kind of preferred form is used to make the equipment that is mainly water base aerosol product, and it comprises:

A kind ofly be used for making activeconstituents to be dispersed in the device that water-based solvent forms solution or suspension;

A kind of be used for will metering said solution or the suspension device that is filled into aerosol canister;

A kind of being used for is installed in device on said jar with valve and injector device; And

A kind of be used for rare gas element is charged into by said valve and injector device said jar so that jar in pressure bring up to be at least 620kPag(20 ℃) device.

Best said jar is a kind of jar of 670ml nominal volume.Preferably set up said jet apparatus so that the solution of 300ml or suspension are injected said jar.Best said pressure is at least 690kPag, and most preferably is 840-1000kPag(20 ℃).Preferably this equipment also comprises a device that is used to install splash head and cap.Preferably the nozzle of splash head or the diameter of spray orifice are 0.3-0.5mm.

Optimal way of the present invention is described now.

According to the present invention, in a preferred method, make water by comprising a set filter of carbon or charcoal filter, to remove impurity wherein, by 0.2 an aseptic μ strainer, enter in the aseptic stainless container at last.Then this sterilized water is cooled to 0-5 ℃ and make its deoxidation, method of deoxidation is to feed till the oxygen in being dissolved in water is removed in the water through the filtering and aseptic carbonic acid gas of 0.2 μ or nitrogen a kind of.Then with this container with carbonic acid gas or nitrogen pressure to about 100kPag.Use a DEPC gauger (play shape batch system (bomb bulk system)) to spray into the composition of activeconstituents and other any needs in this container together then and stirred, to form the aqueous solution or the suspension of a kind of activeconstituents and other compositions.Depress in the charging head that said solution or suspension is transferred to a colloidal sol charging line adding then.In the low pressure tinplate welded tank that the nominal cubic capacity of then solution of 300ml or suspension being packed into is 670ml, and then load onto valve and starter and be fixed on the jar.Then jar is sent to the inflation platform, being charged to pressure with nitrogen herein is 840kPag(20 ℃).Load onto nozzle and cap at last.Provide so for each jar to be equivalent to about 3.4 liters N under 20 ℃ and barometric point ₂Gas, these nitrogen are enough to the 300ml group water solution or the suspension of these activeconstituentss have been sprayed.

For a middle repoussage body aluminium pot, the nitrogen pressure that is charged into is enhanced 950kPag(20 ℃).

The aerocolloidal better formula of a kind of water-base pesticide agent is as follows:

Activeconstituents pyrethrum extract 1.3g

(about 20% pyrethroid)

Piperonyl butoxide 6.0g

Flavouring agent spearmint oil 10.0ml

(cosolvent/sterilant) ethanol 50.0ml

Antioxidants ascorbic acid 0.1g

Aqueous solvent complements to 1000.0ml

Also can adopt other prescription similarly to prepare other aerosol product, for example the fragrance and the deodorising product that use with spray liquid, sterilizing agent, dedusting auxiliary agent (dusting aids), fabric protectant, binding agent and sealing agent, washing composition, starch, lubricant and individual of boiling.

Whether as for requiring water is carried out deoxidation or water is definitely sterilized and then carried out cannedly, this will depend on that activeconstituents in the product or other compositions whether can be owing to oxygenizements or owing to the Decomposition of bacterium is degraded in the product storage process.

The Australian standards AS2278-1986 that Standards Association of Australia (Standards Association of Australia) is formulated the metal aerosol container is consistent with following minimal deformation pressure criteria:

1, low pressure vessel (the tinplate container that weld seam is arranged) must be able to bear 970kPag(55 ℃) pressure;

2, medium pressure vessel (whole aluminum container) must be able to bear 1100kPag(55 ℃) pressure;

3, high pressure vessel must be able to bear 1265kPag(55 ℃) pressure, this standard is applicable to that internal diameter is less than or equal to 75mm, nominal (being full of) volume is less than or equal to the container of 820ml.

Above-mentioned preferred method is based on those aerosol canisters that meet the minimum Australian standards of low-voltage and medium voltage container and sets up.Be appreciated that nitrogen gas pressure just can correspondingly improve so if used jar can bear the minimum sandards pressure that surpasses corresponding to minimal deformation.For example, if low pressure jar can bear the pressure of 1150kPag and not deform, nitrogen gas pressure just can be brought up to 1000kPag(20 ℃ so), this pressure is more much bigger than the pressure of prior art suggestion.

Above-mentioned inflation pressure is determined according to the Pressure/Temperature relation table of following pressurized gas (comprising nitrogen).

Temperature (℃) pressure (kPag) approximation

10 500 960

20 521 1000

30 542 1040

40 564 1080

50 585 1120

55 596 1140

Be readily appreciated that method and apparatus of the present invention can a kind ofly be produced the water-based compressed gas aeerosol product of wide scope to the suitable water-based solvent of required given activity composition by preparing.

Claims

1, the water base aerosol product of a kind of pressurized gas, it comprises:

An aerosol canister, it comprises a valve and injector device, also comprises an intubate when needs;

Be in said jar at a kind of solution or suspension that is mainly one or more activeconstituentss in the water-based solvent; And a kind of pressure is at least the rare gas element propellant of 620kPag (20 ℃).

2, product as claimed in claim 1, wherein water-based solvent is saturated with rare gas element, and said noble gas body is selected from nitrogen, nitrous oxide or carbonic acid gas, most preferably is nitrogen.

3, as the product of claim 1 or 2, wherein water-based solvent is removed the oxygen that is dissolved in wherein by handling with the rare gas element bubbling.

4, as claim 1,2 or 3 product, wherein solution or suspension are filtered removing impurity, and preparation and tinning under appropriate condition.

5, as each described product in the claim 1 to 4, wherein rare gas element under appropriate condition by tinning.

6, as each described product in the claim 1 to 5, wherein solution or suspension also contain for example ethanol of antioxidant such as xitix and cosolvent or sanitas or germ-resistant alcohols except containing one or more activeconstituentss.

7, product as claimed in claim 1, wherein said jar is a kind of low can that is pressed with weld seam, and preferably a kind of nominal volume is 550/670/1, the jar of 400ml.

8, product as claimed in claim 7, wherein the volume of the solution of water base activeconstituents or suspension is about 245/300/245ml respectively.

9,, wherein be used for pressure to the rare gas element of jar pressurization greater than 690kPag as each described product in the claim 1 to 8.

10, product as claimed in claim 9, the pressure of rare gas element wherein are 840-1000kPag(20 ℃).

11, a kind of method that is used to make water base aerosol product, this method comprises:

Preparation is by solution or the suspension of one or more activeconstituentss in being mainly water-based solvent;

The solution or the suspension of aequum are added in the aerosol canister;

Valve and injector device are installed on the jar; And

With a kind of rare gas element jar is pressurized to and is at least 620kPag(20 ℃) pressure.

12, as the method for claim 11, wherein water-based solvent is saturated by rare gas element, and said rare gas element is selected from nitrogen, titanium dioxide phenodiazine or carbonic acid gas, most preferably is nitrogen.

13, as the method for claim 11 or 12, wherein water-based solvent is removed the oxygen that is dissolved in wherein by handling with the rare gas element bubbling.

14, as claim 11,12 or 13 method, wherein solution or suspension is through filtering removing impurity, and preparation and tinning under appropriate condition.

15, as each described method in the claim 11 to 14, wherein rare gas element is loaded under appropriate condition.

16, as each described method in the claim 11 to 15, wherein solution or suspension also contain antioxidant such as xitix and cosolvent or sanitas or germ-resistant alcohols such as ethanol except containing activeconstituents.

17, as the method for claim 11, wherein said jar is a kind of low can that is pressed with weld seam, and preferably a kind of nominal volume is 550/670/1, the jar of 400ml.

18, as the method for claim 17, wherein the volume of the solution of water base activeconstituents or suspension is about 245/300/625ml respectively.

19,, wherein be used for pressure to the rare gas element of jar pressurization greater than 690kPag as each described method in the claim 11 to 18.

20, as the method for claim 19, wherein the pressure of rare gas element is 840-1000kPag(20 ℃).

21, be used to make the equipment that is mainly water base aerosol product, this equipment comprises:

A kind ofly be used for preparing the solution that forms at water-based solvent by activeconstituents or the device of suspension;

A kind of be used for will metering said solution or the suspension device that adds to aerosol canister;

A kind of being used for is installed in device on said jar with a valve and injector device; And

A kind ofly be used for rare gas element is charged to by said valve and injector device said jar, be at least 620kPag(20 ℃ so that its pressure reaches) device.

22, as the equipment of claim 21, come the device of saturation water based solvent comprising a kind of with rare gas element, wherein said rare gas element is selected from nitrogen, nitrous oxide or carbonic acid gas, most preferably is nitrogen.

23, as the equipment of claim 21 or 22, comprising a kind of by come the treating water based solvent with the rare gas element bubbling to remove the bubbling device that is dissolved in oxygen wherein.

24, as claim 21,22 or 23 equipment, comprising a kind of filtering solution or suspension of being used for the device of removing impurity and be used for the device that under conditions suitable, is prepared and the device that injects product.

25, as each described equipment in the claim 21 to 24, comprising a kind of device that is used under conditions suitable, charging into rare gas element.

26, as each described equipment in the claim 21 to 25, wherein solution or suspension also contain antioxidant such as xitix except containing activeconstituents, and cosolvent or sanitas or germ-resistant alcohol such as ethanol.

27, as each described equipment in the claim 21 to 26, it comprises that one is charged to the device of pressure greater than 690kPag with rare gas element.

28, product as claimed in claim 9, wherein the pressure of rare gas element is 840-1000kPag(20 ℃)