CN108403615A - Composition including batyl alcohol isostearate and its application in cosmetics - Google Patents
Composition including batyl alcohol isostearate and its application in cosmetics Download PDFInfo
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- CN108403615A CN108403615A CN201810316007.2A CN201810316007A CN108403615A CN 108403615 A CN108403615 A CN 108403615A CN 201810316007 A CN201810316007 A CN 201810316007A CN 108403615 A CN108403615 A CN 108403615A
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- core material
- wall material
- mass ratio
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- batyl alcohol
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9794—Liliopsida [monocotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/11—Encapsulated compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/20—Halogens; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/37—Esters of carboxylic acids
- A61K8/375—Esters of carboxylic acids the alcohol moiety containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/733—Alginic acid; Salts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/736—Chitin; Chitosan; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/99—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/56—Compounds, absorbed onto or entrapped into a solid carrier, e.g. encapsulated perfumes, inclusion compounds, sustained release forms
Abstract
The present invention relates to a kind of composition including batyl alcohol isostearate and its in the application of cosmetics.Wherein, the composition including batyl alcohol isostearate includes several microsphere structures, wherein the microsphere structure includes wall material and core material, and the wall material coats the core material;The wherein described core material includes the component of following mass fraction:43~96 parts of 2.5~6 parts of batyl alcohol isostearate, 0.02~0.05 part of placenta stem-cell and intermixture.The above-mentioned composition for including batyl alcohol isostearate has good emulsification, dispersion, lubricating ability, additionally it is possible to realize whitening, anti-aging and repair epidermis and other effects.
Description
Technical field
The present invention relates to application field, more particularly to including batyl alcohol isostearate composition and its in cosmetics
Application.
Background technology
Originally separation obtains batyl alcohol (BATYL ALCOHOL) from shark cod-liver oil, also has presence in animal yellow marrow.
Batyl alcohol is intrinsic substance in animal body, and content is more in marrow hemopoiesis tissue, it may be possible to which one of internal Hemopoietic factor can rise
The megacaryocyte and granulocyte number that height is reduced by radioactive ray, and life cycle can be extended.Have and promotes leucocyte hyperplasia and anti-radiation line
Effect, Neuroleptic Leukocytopenia can be prevented, hemopoietic system can be also fought caused by benzene poisoning and cytotoxic drug and inhibit.Shark
Liver alcohol stearate (BATYL STEARATE, No. CAS:13232-26-3) it is batyl alcohol and stearic ester type compound.It is right
It is in the starting stage in the research of batyl alcohol stearate, applicant is carrying out grinding for the composition of batyl alcohol stearate
Study carefully and its using research and development.
Invention content
Based on this, it is necessary to provide a kind of composition including batyl alcohol isostearate and its application in cosmetics.
A kind of composition including batyl alcohol isostearate comprising several microsphere structures, wherein the microsphere
Structure includes wall material and core material, and the wall material coats the core material;The wherein described core material includes the component of following mass fraction:Shark
43~96 parts of 2.5~6 parts of liver alcohol isostearate, 0.02~0.05 part of placenta stem-cell and intermixture.Above-mentioned includes shark liver
The composition of alcohol isostearate has good emulsification, dispersion, lubricating ability, additionally it is possible to realize whitening, slow down aging and repair
Multiple epidermis and other effects.
Further, the intermixture includes water in one of the embodiments,.
Further, in one of the embodiments, the core material include following mass fraction component:Batyl alcohol is different hard
2.5~6 parts of resin acid ester, 0.2~0.8 part of Bai Shi ash jasmines flower extract, 0.3~1.3 part of Spiraea ulmaria leaf extract, corn poppy spend
0.2~0.8 part of valve extract, 0.1~0.5 part of golden hairpin dendrobium extract, 0.02~0.05 part of placenta stem-cell and intermixture
43~96 parts.
The wall material includes sodium alginate, calcium chloride and/or chitosan in one of the embodiments,.
The wall material includes sodium alginate, calcium chloride and chitosan in one of the embodiments, wherein sodium alginate,
Calcium chloride and chitosan mass ratio are " 2~5 ":" 0.5~1.5 ":" 1~6 ".
The microsphere structure is provided at least ten blind holes in the wall material in one of the embodiments,.
Each blind hole is uniformly distributed in the wall material in one of the embodiments,.
Each blind hole is set on the outer surface of the wall material in one of the embodiments,.
The depth of the blind hole is the 30%~50% of the thickness of the wall portion of the wall material in one of the embodiments,.
The microsphere structure offers at least three crank slots in the wall material in one of the embodiments,.
The intermixture includes water, surfactant, emulsifier and moisturizer in one of the embodiments, wherein table
Face activating agent, emulsifier, moisturizer and water mass ratio be " 1~2 ":" 2~5 ":" 1~5 ":" 31~93 ".
Application of the composition including batyl alcohol isostearate in cosmetics described in any one.
The cosmetics include lipstick, massage cream, facial mask or skin cream etc. in one of the embodiments,.
Description of the drawings
The present invention is without attached drawing.
Specific implementation mode
In order to make the foregoing objectives, features and advantages of the present invention clearer and more comprehensible, below in conjunction with the accompanying drawings to the present invention
Specific implementation mode be described in detail.Many details are elaborated in the following description in order to fully understand this hair
It is bright.But the invention can be embodied in many other ways as described herein, those skilled in the art can be not
Similar improvement is done in the case of violating intension of the present invention, therefore the present invention is not limited by following public specific embodiment.
It should be noted that when element is referred to as " being fixed on " or " being set to " another element, it can be directly another
On one element or there may also be elements placed in the middle.When an element is considered as " connection " another element, it can be with
It is directly to another element or may be simultaneously present centering elements.Term as used herein " vertically ", " level
", "left", "right" and similar statement for illustrative purposes only, be not offered as being unique embodiment.
Unless otherwise defined, all of technologies and scientific terms used here by the article and belong to the technical field of the present invention
The normally understood meaning of technical staff is identical.Used term is intended merely to describe specific reality in the description of the invention
Apply the purpose of mode, it is not intended that in the limitation present invention.Term " and or " used herein includes one or more relevant
Any and all combinations of Listed Items.
One embodiment of the invention is a kind of composition including batyl alcohol isostearate comprising several microspheres
Structure, wherein the microsphere structure includes wall material and core material, and the wall material coats the core material;The wherein described core material includes
The component of following mass fraction:2.5~6 parts of batyl alcohol isostearate, 0.02~0.05 part of placenta stem-cell and intermixture
43~96 parts.The above-mentioned composition for including batyl alcohol isostearate has good emulsification, dispersion, lubricating ability, additionally it is possible to
It realizes whitening, anti-aging and repairs epidermis and other effects.For example, a kind of composition including batyl alcohol isostearate, packet
Include several microsphere structures, wherein the microsphere structure includes wall material and core material, and the wall material coats the core material;Wherein
The core material includes the component of following mass fraction:3~5.5 parts of batyl alcohol isostearate, placenta stem-cell 0.03~0.04
50~90 parts of part and intermixture;For example, the core material includes the component of following mass fraction:Batyl alcohol isostearate 2.5
43 parts of part, 0.05 part of placenta stem-cell and intermixture;Alternatively, the core material includes the component of following mass fraction:Batyl alcohol
96 parts of 6 parts of isostearate, 0.02 part of placenta stem-cell and intermixture;Alternatively, the core material includes following mass fraction
Component:90 parts of 3 parts of batyl alcohol isostearate, 0.04 part of placenta stem-cell and intermixture;Alternatively, the core material includes following
The component of mass fraction:50 parts of 5.5 parts of batyl alcohol isostearate, 0.03 part of placenta stem-cell and intermixture;Alternatively, described
Core material includes the component of following mass fraction:4 parts of batyl alcohol isostearate, 0.035 part of placenta stem-cell and intermixture 60
Part;Alternatively, the core material includes the component of following mass fraction:4.5 parts of batyl alcohol isostearate, 0.03 part of placenta stem-cell
And 65 parts of intermixture.
In each embodiment, the thickness of the wall material is arranged according to demand, for different cosmetics, the thickness of the wall material
Difference, for example, for facial cleanser, facial mask, massage cream and lipstick, the thickness sequence of the wall material increases setting, for example, the wall
The thickness of material is 0.5~1000 micron, and for another example, the thickness of the wall material is 1~100 micron, and for another example, the thickness of the wall material is
2~50 microns, for another example, the thickness of the wall material is 3~10 microns, according to different demands flexible design.For another example, the wall
The mass ratio of material and the core material is (1~10):(1~10), for example, the wall material and the mass ratio of the core material are
10:1、1:1 or 1:10 etc., in this way, can be according to microsphere structure described in different demands flexible design.Further, described micro-
A diameter of 1.2~2500 microns of sphere structure, for another example, a diameter of 2.5~250 microns of the microsphere structure, for another example, institute
State microsphere structure a diameter of 5~120 microns, for another example, a diameter of 7~30 microns of the microsphere structure, and so on.
Further, the intermixture includes water in one of the embodiments,.Further, described in one of the embodiments,
Water is pure water or deionized water.In one of the embodiments, the intermixture include water, surfactant, emulsifier with
Moisturizer, wherein surfactant, emulsifier, moisturizer and water mass ratio be " 1~2 ":" 2~5 ":" 1~5 ":“31
~93 ";For example, in the intermixture, surfactant, emulsifier, moisturizer and water mass ratio be 1.5:3:2.5:45;
For another example, in the intermixture, surfactant, emulsifier, moisturizer and water mass ratio be 2:4.5:3.5:88.For example,
The core material includes 56 parts of 5 parts of batyl alcohol isostearate, 0.04 part of placenta stem-cell and intermixture, wherein the mixing
Agent includes 3 parts of 50 parts of water, 1 part of surfactant, 2 parts of emulsifier and moisturizer, remaining embodiment and so on.
For example, the emulsifier includes glycerol monolaurate, dilaurin and/or glycerine myristate ester;Into
One step, the emulsifier includes that mass ratio is " 2~4 ":" 1~3 ":The glycerol monolaurate of " 1~5 ", two bay of glycerine
Acid esters and glycerine myristate ester;For example, it is 2 that the emulsifier, which includes mass ratio,:1:1 glycerol monolaurate, glycerine two
Laurate and glycerine myristate ester;For another example, it is 2 that the emulsifier, which includes mass ratio,:3:It is 5 glycerol monolaurate, sweet
Oily dilaurate and glycerine myristate ester;For another example, the emulsifier further includes the smooth oleate of sorb and/or the smooth sesquialter of sorb
The dosage of oleate, the smooth oleate of sorb and/or sorbitan sesquioleate should not be excessive, for example, the emulsifier includes matter
Amount ratio is " 0.5~1 ":" 2~4 ":" 1~3 ":The smooth oleate of sorb, glycerol monolaurate, the glycerine tin dilaurate of " 1~5 "
Ester and glycerine myristate ester;For example, it is 0.6 that the emulsifier, which includes mass ratio,:2.5:2.5:The 2.5 smooth oleic acid of sorb
Ester, glycerol monolaurate, dilaurin and glycerine myristate ester.For another example, the emulsifier includes that mass ratio is
" 0.5~1 ":" 0.2~0.5 ":" 2~4 ":" 1~3 ":The smooth oleate of sorb, sorbitan sesquioleate, the glycerine of " 1~5 "
Laurate, dilaurin and glycerine myristate ester;For example, it is 0.6 that the emulsifier, which includes mass ratio,:0.4:
4:3:The 2 smooth oleate of sorb, sorbitan sesquioleate, glycerol monolaurate, dilaurin and glycerine nutmeg
Acid esters.It is appreciated that these emulsifier components can with auxiliary other purposes of work such as detergent, moisturizer or foam improver,
Herein only its mass fraction or mass ratio are calculated as emulsifier.
Further, the surfactant is or including amino acid surfactant, ammonia in one of the embodiments,
Base acid surfaces activating agent have the advantages that it is safe, mild and non-stimulated, be suitable for various skin quality, make particularly suitable as cosmetics
With.The amino acid surfactant includes sodium lauroyl glutamate, myristoyl glutamate in one of the embodiments,
Sodium, cocounut oil acyl glycine potassium and/or cocoyl glutamic acid triethanolamine salt;In each related embodiment, cocounut oil acyl glycine potassium
Sodium cocoyl glycinate replacement can be used;Further, the amino acid surfactant further includes methyl cocoyl ox sulphur
Sour sodium.For example, it is 1 that the amino acid surfactant, which includes mass ratio,:1 sodium lauroyl glutamate and myristoyl paddy ammonia
Sour sodium;For another example, it is 1 that the amino acid surfactant, which includes mass ratio,:2:1 sodium lauroyl glutamate, the sweet ammonia of cocounut oil acyl
Sour potassium and sodium methyl cocoyl taurate;For another example, it is 1 that the amino acid surfactant, which includes mass ratio,:2:0.5 meat
Myristoyl sodium glutamate, cocoyl glutamic acid triethanolamine salt and sodium methyl cocoyl taurate;For another example, the amino acid
Surfactant includes that mass ratio is 1:2:1:0.8 sodium lauroyl glutamate, myristoyl glutamate sodium, cocoyl paddy
Propylhomoserin triethanolamine salt and sodium methyl cocoyl taurate;For another example, the amino acid surfactant includes that mass ratio is
1:1:2:1 myristoyl glutamate sodium, sodium cocoyl glycinate, cocoyl glutamic acid triethanolamine salt and methyl cocoyl acyl
Base sodium taurocholate;For another example, it is 1 that the amino acid surfactant, which includes mass ratio,:1:1:1:0.8 myristoyl glutamate
Sodium, myristoyl glutamate sodium, cocounut oil acyl glycine potassium, cocoyl glutamic acid triethanolamine salt and methyl cocoyl ox sulphur
Sour sodium;For another example, it is 1 that the amino acid surfactant, which includes mass ratio,:1:1:2:1 myristoyl glutamate sodium, Pork and beans
Cool acyl sodium glutamate, sodium cocoyl glycinate, cocoyl glutamic acid triethanolamine salt and sodium methyl cocoyl taurate.It can
To understand, these surfactant components can only be used as surfactant herein with auxiliary other purposes of work such as moisturizer
Calculate its mass fraction or mass ratio.For example, the intermixture includes 1 part of amino acid surfactant, the amino acid
Surfactant includes that mass ratio is 1:1:2:1 myristoyl glutamate sodium, sodium cocoyl glycinate, cocoyl paddy ammonia
Triethylenetetraminehexaacetic acid alcohol amine salt and sodium methyl cocoyl taurate, that is, the amino acid surfactant includes myristoyl glutamate
0.2 part of sodium, 0.2 part of sodium cocoyl glycinate, 0.4 part of cocoyl glutamic acid triethanolamine salt and methyl cocoyl taurine
0.2 part of sodium, remaining embodiment and so on.
Further, the moisturizer includes hyaluronic acid in one of the embodiments, and hyaluronic acid is D-Glucose
The dissacharide units sodium hyaluronate (Hyaluronan, also known as Hyaluronic Acid) of aldehydic acid and N-acetyl-glucosamine composition, it is also known as sugared
Aldehydic acid, is a kind of acid mucopolysaccharide, and basic structure is by two dissacharide units D-Glucose aldehydic acid and N-acetyl-glucosamine group
At large-scale polysaccharide, molecule can carry 500 times or more of moisture, using hyaluronic acid product is contained, can improve drying
There is the skin of wrinkle, has kept its recovery original smooth and elastic.It is imitated in order to further enhance the moisturizing of the composition
Fruit, in each embodiment, the moisturizer further includes ceramide (ceramide);Ceramide is a kind of fat for being present in skin
Class.Also known as sphingolipid plays an important role in epidermal keratinocytes layer formation process.Ceramide is that sphingolipid is total
Some structural units.Ceramide local use can cause skin electric conductivity clearly to increase, cholesterol secondly, free-fat
Acid and cholesteryl ester act on then unobvious.Ceramide has hydrone ability of associating by force very much, it in cuticula by forming
Reticular structure maintains moisture of skin.Also, ceramide content in horny layer of epidermis can be made to increase using ceramide, can improved
The situations such as dry skin, furfur, coarse;Ceramide can increase epidermal keratinocytes layer thickness simultaneously, improve skin moisture holding capacity, subtract
Few wrinkle, enhances skin elasticity, delay skin aging.For example, in each embodiment, the moisturizer includes hyaluronic acid and nerve
Amide, and the mass ratio of hyaluronic acid and ceramide is 5:1.For another example, one embodiment in each embodiment or wherein
In, the moisturizer includes at least one of glycerine, butanediol, pentanediol, hexylene glycol and hyaluronic acid.For example, described
Moisturizer is glycerine, butanediol, pentanediol, hexylene glycol or hyaluronic acid.The moisturizer packet in one of the embodiments,
It is 2 to include mass ratio:1:1 glycerine, pentanediol and hexylene glycol;For example, the intermixture of the core material includes moisturizer 4
Part, remaining be water or remaining be water, surfactant and emulsifier, remaining embodiment.For example, the core material packet
4 parts of moisturizer is included, the moisturizer includes that mass ratio is 2:1:1 glycerine, pentanediol and hexylene glycol presses mass fraction
The moisturizer includes 1 part of 2 parts of glycerine, 1 part of pentanediol and hexylene glycol, remaining embodiment and so on.A reality wherein
It applies in example, the moisturizer includes that mass ratio is 14:1 glycerine and hyaluronic acid.For example, the core material includes moisturizer
3 parts, the moisturizer includes that mass ratio is 14:1 glycerine and hyaluronic acid include by moisturizer described in mass fraction
0.2 part of 2.8 parts of glycerine and hyaluronic acid, remaining embodiment and so on.The core material of composition has fairly good guarantor in this way
Wet effect.
The core material further includes epidermal stem cells in one of the embodiments, and in the core material, epidermal stem cells with
The mass ratio of placenta stem-cell is " 4 to 10 ":10;For example, in the core material, the quality of epidermal stem cells and placenta stem-cell
Ratio is " 5 to 9 ":10;For example, in the core material, the mass ratio of epidermal stem cells and placenta stem-cell is " 6 to 8 ":10;
For example, in the core material, the mass ratio of epidermal stem cells and placenta stem-cell is 7:10.Institute in one of the embodiments,
It further includes colony-stimulating factor to state core material, and in the core material, the quality of colony-stimulating factor and placenta stem-cell
Ratio is " 1 to 2 ":10.For example, in the core material, the mass ratio of colony-stimulating factor and placenta stem-cell is " 1.2
To 1.8 ":10;For example, in the core material, the mass ratio of colony-stimulating factor and placenta stem-cell is 1.5:10.At it
In middle one embodiment, the core material further includes oligopeptides, and in the core material, and the mass ratio of oligopeptides and placenta stem-cell is " 5
To 15 ":10.For example, in the core material, the mass ratio of oligopeptides and placenta stem-cell is " 6 to 12 ":10.For example, the core material
In, the mass ratio of oligopeptides and placenta stem-cell is " 9 or 10 ":10.The oligopeptides is oligopeptides-in one of the embodiments,
3.Further, the core material includes 0.02~0.05 part of placenta stem-cell in one of the embodiments, and the core material packet
It is " 4 to 10 " to include mass ratio:" 1 to 2 ":" 5 to 15 ":10 epidermal stem cells, colony-stimulating factor, oligopeptides and tire
Disk stem cell.For example, it is " 5 to 9 " that the core material, which includes mass ratio,:" 1.2 to 1.8 ":" 6 to 12 ":10 epidermal stem cells,
Colony-stimulating factor, oligopeptides and placenta stem-cell;For another example, it is " 6 to 8 " that the core material, which includes mass ratio,:" 1.4 to
1.6”:" 7 to 10 ":10 epidermal stem cells, colony-stimulating factor, oligopeptides and placenta stem-cell;For another example, the core material
It is 7 including mass ratio:1.5:8:10 epidermal stem cells, colony-stimulating factor, oligopeptides and placenta stem-cell.At it
In middle one embodiment, the core material includes 0.02 part of placenta stem-cell, and the core material includes that mass ratio is 4:1:5:10
Epidermal stem cells, colony-stimulating factor, oligopeptides -3 and placenta stem-cell, i.e., the described core material includes epidermal stem cells
0.02 part of 0.008 part, 0.002 part of colony-stimulating factor, 0.01 part of oligopeptides -3 and placenta stem-cell, epidermal stem cells,
Colony-stimulating factor, oligopeptides -3 and placenta stem-cell add up to 0.04 part, remaining embodiment and so on.
Further, the core material further includes the component of following mass fraction:Bai Shi ash jasmine flower extracts (FAGRAEA
BERTERROANA) 0.2~0.8 part, 0.3~1.3 part of Spiraea ulmaria (SPIRAEA ULMARIA) leaf extract, corn poppy
0.2~0.8 part of (PAPAVER RHOEAS) petal extract and HERBA DENDROBII (DENDROBIUM NOBILE) extract 0.1~
At least one of 0.5 part;For example, the core material further includes the component of following mass fraction:Bai Shi ash jasmines flower extract 0.2
~0.8 part, 0.3~1.3 part of Spiraea ulmaria leaf extract, 0.2~0.8 part of corn poppy's petal extract or golden hairpin dendrobium extract
0.1~0.5 part;For another example, the core material further includes the component of following mass fraction:0.2~0.8 part of Bai Shi ash jasmines flower extract,
0.3~1.3 part of Spiraea ulmaria leaf extract, 0.2~0.8 part of corn poppy's petal extract and golden hairpin dendrobium extract 0.1~0.5
At least within the two or whole of part.Further, the core material includes following mass fraction in one of the embodiments,
Component:0.2~0.8 part of Bai Shi ash jasmines flower extract, 0.3~1.3 part of Spiraea ulmaria leaf extract, corn poppy's petal extract
0.2~0.8 part with 0.1~0.5 part of golden hairpin dendrobium extract at least one, 2.5~6 parts of batyl alcohol isostearate,
43~96 parts of 0.02~0.05 part of placenta stem-cell and intermixture.Further, the core material in one of the embodiments,
Include the component of following mass fraction:2.5~6 parts of batyl alcohol isostearate, 0.2~0.8 part of Bai Shi ash jasmines flower extract, elm
0.3~1.3 part of japanese spiraea leaf extract, 0.2~0.8 part of corn poppy's petal extract, 0.1~0.5 part of golden hairpin dendrobium extract,
43~96 parts of 0.02~0.05 part of placenta stem-cell and intermixture.Further, the core material in one of the embodiments,
Include the component of following mass fraction:3~5.5 parts of batyl alcohol isostearate, 0.3~0.7 part of Bai Shi ash jasmines flower extract, elm
0.4~1.2 part of japanese spiraea leaf extract, 0.3~0.7 part of corn poppy's petal extract, 0.2~0.4 part of golden hairpin dendrobium extract,
50~90 parts of 0.03~0.04 part of placenta stem-cell and intermixture.Further, the core material in one of the embodiments,
Include the component of following mass fraction:3.5~5 parts of batyl alcohol isostearate, 0.4~0.6 part of Bai Shi ash jasmines flower extract, elm
0.5~1 part of japanese spiraea leaf extract, 0.4~0.6 part of corn poppy's petal extract, 0.25~0.35 part of golden hairpin dendrobium extract,
55~85 parts of 0.03~0.04 part of placenta stem-cell and intermixture.For example, the core material includes the component of following mass fraction:
5 parts of batyl alcohol isostearate, 0.5 part of Bai Shi ash jasmines flower extract, 0.75 part of Spiraea ulmaria leaf extract, corn poppy's petal carry
Take 55 parts of 0.5 part of object, 0.25 part of golden hairpin dendrobium extract, 0.025 part of placenta stem-cell and intermixture.Further, described
Core material further includes the component of following mass fraction:Arginine/0.01~0.03 part of lysine polypeptide.For example, the core material includes
The component of following mass fraction:4 parts of batyl alcohol isostearate, 0.8 part of Bai Shi ash jasmines flower extract, Spiraea ulmaria leaf extract
1.2 parts, 0.4 part of corn poppy's petal extract, 0.2 part of golden hairpin dendrobium extract, 0.04 part of placenta stem-cell, 92 parts of intermixture with
And arginine/0.02 part of lysine polypeptide.Such component design can realize that whitening and anti-aging and recovery epidermis are equivalent
Fruit is suitable for various cosmetics.
Further, the core material further includes camomile (DENDRANTHEMA in one of the embodiments,
LAVANDULIFOLIUM) 2~5 parts of extract.Further, the core material further includes 3~4 parts of Flos Chrysanthemi extract;Further
Ground, the core material further include 3.5 parts of Flos Chrysanthemi extract.For example, the core material of each embodiment further include Flos Chrysanthemi extract 2,3,
3.5,4 or 5 parts.In this way, the composition has the technique effect for allergy of preferably releiving.And/or one embodiment wherein
In, the core material further includes 5~15 parts of sweet wild marjoram (ORIGANUM MAJORANA) caul-fat.Sweet wild marjoram is also known as marjoram.Further
Ground, the core material further include 1~5 part of sweet wild marjoram caul-fat;Further, the core material further includes 2~4 parts of sweet wild marjoram caul-fat.Example
Such as, the core material of each embodiment further include sweet wild marjoram caul-fat 1,2,3,4 or 5 parts.It is preferably grown in this way, the composition has
Moisten the technique effect of nursing.And/or the core material further includes American Ginseng (PANAX in one of the embodiments,
QUINQUEFOLIUM) 2~6 parts of extract.Further, the core material further includes 3~5 parts of American ginseng extract;Further
Ground, the core material further include 4 parts of American ginseng extract.For example, the core material of each embodiment further include American ginseng extract 2,
3,4,5 or 6 parts.In this way, the composition has the technique effect for preferably moistening nursing.And/or further, each to implement
In example, the core material further includes 1~4 part of Chinese herbaceous peony (PAEONIA ALBIFLORA) root extract;Further, the core material is also
Including 2~3 parts of Chinese herbaceous peony root extract;Further, the core material further includes 2.5 parts of Chinese herbaceous peony root extract;For example, each embodiment
The core material further include Chinese herbaceous peony root extract 1,2,2.5,3 or 4 parts, in this way, the composition have better whitening spot-removing
Technique effect.And/or further, in each embodiment, the core material further includes Rhizoma Atractylodis Macrocephalae (ATRACTYLOIDES
MACROCEPHALA) 2~4 parts of root extract;For example, the core material of each embodiment further includes Rhizoma Atractylodis Macrocephalae root extract 2,3 or 4
Part, in this way, the composition has better whitening, nti-freckle, soft and moist and nourishing technique effect.Further, each embodiment
In, the core material further includes 1~3 part of radix scutellariae (SCUTELLARIA BAICALENSIS) root extract;For example, each embodiment
The core material further includes 1,2 or 3 part of radix scutellariae root extract, in this way, the composition have preferably releive, antiallergic and soft and moist
Technique effect.Further, in each embodiment, the core material further includes Radix Salviae Miltiorrhizae (SALVIA MILTIORRHIZA) root extract 2
~4 parts;For example, the core material of each embodiment further includes 2,3 or 4 parts of Radix Salviae Miltiorrhizae root extract, in this way, the composition has more
Good moisturizing and oxidation resistant effect.It is appreciated that save space and according to the explanations of the various embodiments described above it is found that this hair
Bright embodiment further includes that the Flos Chrysanthemi extract with above-mentioned mass component, sweet wild marjoram caul-fat, American ginseng extract, Peony Root carry
Object, Rhizoma Atractylodis Macrocephalae root extract, radix scutellariae root extract and/or Radix Salviae Miltiorrhizae root extract are taken, details are not described herein.Further, each to implement
In example, the mass ratio of Flos Impatientis leaf extract and Flos Chrysanthemi extract is 2:1.Further, in each embodiment, American Ginseng extraction
The mass ratio of object and sweet wild marjoram caul-fat is 2:3.In order to adjust pH value, further, in each embodiment, according to target pH need
It asks, the core material further includes 0.1~12 part of sodium hydroxide or potassium hydroxide.
The core material further includes 2~6 parts of aminoacid ingredient in one of the embodiments,.In one of the embodiments,
The aminoacid ingredient includes glycine (GLYCINE), proline (PROLINE), alanine (ALANINE), threonine
(THREONINE), valine (VALINE) and at least two kinds in leucine (LEUCINE).Institute in one of the embodiments,
State aminoacid ingredient include mass ratio be 2:1:1.5 glycine, proline and alanine.In one of the embodiments,
The aminoacid ingredient includes that mass ratio is 1:1:1 glycine, threonine and leucine.In one of the embodiments,
The aminoacid ingredient further includes histidine (HISTIDINE), for example, the aminoacid ingredient includes glycine, proline, third
At least two kinds in propylhomoserin, threonine, histidine, valine and leucine;For another example, the aminoacid ingredient include glycine,
At least two kinds in proline, alanine, threonine, valine and leucine and histidine.Further, histidine is in institute
It is 10%~18% to state the mass ratio in aminoacid ingredient.For another example, it is 2 that the aminoacid ingredient, which includes mass ratio,:1:
1.5:1.5:2:2:1.5 glycine, proline, alanine, threonine, valine, leucine and histidine.For example, each reality
It further includes 5.75 parts of aminoacid ingredient to apply the example core material, and the aminoacid ingredient includes that mass ratio is 2:1:1.5:1.5:2:
2:1.5 glycine, proline, alanine, threonine, valine, leucine and histidine presses amino described in mass fraction
Sour component includes 1 part of glycine, 0.5 part of proline, 0.75 part of alanine, 0.75 part of threonine, 1 part of valine, 1 part of leucine
With 0.75 part of histidine, mass ratio of the histidine in the aminoacid ingredient is about 13% at this time, remaining embodiment is with this
Analogize.Wherein, glycine has the function of moisturizer and skin conditioner, can enhance skin opsonizing capacity;Proline, which has, to be protected
Wet and shortening skin plays the role of cutin-softening layer, and cosmetics is contributed to realize whitening effect;Alanine has moisturizing, anti-inflammatory and anti-
Oxidation helps to promote cell metabolism ability, cosmetics is contributed to realize anti-wrinkle effect;Threonine have moisturizing,
Antistatic and protection cell membrane effect, contributes to the whitening function for promoting cosmetics, and have the effect of conditioning hair;Valine
Have the function of moisturizer and skin conditioner, contributes to the skin opsonic action for promoting cosmetics, and with promotion growth
Effect;Leucine has moisturizing and anti-inflammatory effect, with lipophilicity, contributes to the cutin-softening layer effect for promoting cosmetics;
Histidine has antistatic and anti-inflammatory effect, contributes to the whitening and the sun-proof result that promote cosmetics.
The wall material includes sodium alginate, calcium chloride and/or chitosan in one of the embodiments,.Sodium alginate is
By-product after extracting iodine and mannitol in the kelp or sargassum of brown algae, molecule is by beta-D-mannuronic acid (β-
D-mannuronic, M) and α-L- guluronic acids (α-L-guluronic, G) be formed by connecting.The aqueous solution of sodium alginate has
Higher viscosity has been used as thickener, stabilizer, emulsifier of food etc..Sodium alginate contains a large amount of-COO, in water
It can express out polyanion behavior in solution, there is certain adhesion, can be used as the pharmaceutical carrier for treating mucous membrane tissue.In acid
Under the conditions of property ,-COOIt is transformed into-COOH, degree of ionization reduces, and the hydrophily of sodium alginate reduces, and strand is shunk, and pH value increases
Added-time ,-COOH group constantly dissociate, and the hydrophily of sodium alginate increases, molecule chain-unfolding.Therefore, sodium alginate has bright
Aobvious pH sensibility.Sodium alginate can quickly form gel under conditions of extremely mild, when there is Ca2+、Sr2+Equal cations
In the presence of, the Na on G units+Ion-exchange reactions occurs with bivalent cation, G units are accumulated to form cross-linked network structure, from
And form hydrogel.Sodium alginate forms the mild condition of gel, this can be to avoid sensitive drug, protein, cell and enzyme
The inactivation of isoreactivity substance.Chitosan (Chitosan) is also known as chitosan, is the chitin being widely present by nature
(Chitin) pass through what deacetylation obtained, chemical name is Chitosan (1-4) -2- amino-B-D glucose, and N- is de-
Acetyl degree is low deacetylation chitosan 55%~70%, and 70%~85% is middle deacetylation chitosan, 85%~
95% be chitosan with high deacetylation degree, and 95%~100% is chitosan with ultrahigh deacetylation degree.Each glycosyl of chitin
On, there may be N- acetyl group, may there is no N- acetyl group, it is also possible to have N- acetyl group, every N- acetyl degree is below 50%
, it is all referred to as chitin, has the function of good moisture absorption, moisturizing, conditioning, antibacterial etc.;Suitable for skin cream, shower
The cosmetics such as dew, facial cleanser, mousse, high-grade cream, lotion, colloid, are also used in the medicine such as pulsed light, radio frequency, dot matrix, tartaric acid
Play the role of natural antibiotics after cosmetology and come antiallergic sense and anti-inflammatory generation, quickly repairs substrate thermal damage, quickly heal
Wound repairs epidermal barrier, and the skin care item of chitosan also have the effect for being metabolized heavy metal, particularly suitable for including shark
The composition of liver alcohol isostearate is simultaneously used as cosmetics.The wall material includes alginic acid in one of the embodiments,
Sodium, calcium chloride and chitosan, wherein sodium alginate, calcium chloride and chitosan mass ratio are " 2~5 ":" 0.5~1.5 ":“1
~6 ";Sodium alginate coordinates calcium chloride, can form cross-linked network structure, to form hydrogel, is particularly suitable for facial mask, lipstick
Equal cosmetics.Further, the wall material includes sodium alginate, calcium chloride and chitosan in one of the embodiments,
In, sodium alginate, calcium chloride and chitosan mass ratio are " 4.5~5 ":" 0.5~0.6 ":" 1~2 ".For example, the wall material
Including sodium alginate, calcium chloride and chitosan, wherein sodium alginate, calcium chloride and chitosan mass ratio are 3:1:2.In this way
Structure design so that the wall material of the composition can be ruptured in stress, to disengage the various components in core material.
Further, the wall material has wall portion, the heterogeneous setting of wall portion, for example, the wall portion in one of the embodiments,
Including thick portion and thin portion, the thickness proportion in the thickness portion and the thin portion is " 1.5~2.5 ":1;For example, the thin portion is part
Spherical or part ellipsoidal shape;For example, the wall portion includes at least three thin portions.In this way so that the composition it is described
Microsphere structure can have priority rupture sequence, most of component first to be disengaged from the thin portion of rupture in stress, remaining set
It point is disengaged again from the rupture location in thick portion, disengages effect so as to reach band form so that the microsphere structure exists
The cosmetics for having various subsequent designs in different cosmetics, and then reaching existing various homogeneous outputs cannot achieve pre-
Effect except material, such as moisturizing, skin care, nourishing and other effects.
The microsphere structure is provided at least eight blind holes in the wall material in one of the embodiments,;Wherein one
In a embodiment, the microsphere structure is provided at least ten blind holes in the wall material;It is described micro- in one of the embodiments,
Sphere structure is provided at least 12 blind holes in the wall material;Further, the blind hole include sodium alginate, calcium chloride and/
Or chitosan.For example, the blind hole includes sodium alginate, calcium chloride and chitosan, wherein sodium alginate, calcium chloride and shell are poly-
Sugared mass ratio is " 2~5 ":" 0.5~1.5 ":" 1~6 ".For example, the blind hole includes that sodium alginate, calcium chloride and shell are poly-
Sugar, wherein sodium alginate, calcium chloride and chitosan mass ratio are 2:0.8:3.Further, the quantity of the blind hole is even
Number;Each blind hole is uniformly distributed in the wall material in one of the embodiments,.Each institute in one of the embodiments,
Blind hole is stated to be set on the outer surface of the wall material.Further, each blind hole is evenly distributedly set to the wall material
On outer surface, for example, the regular line of each blind hole forms a regular polygon, alternatively, each blind hole is located at one
At each vertex position of a regular polygon, for example, the regular polygon be regualr decagon, dodecagon, positive ten quadrangle,
Positive ten hexagon, positive icosagon etc..The depth of the blind hole is the thickness of the wall portion of the wall material in one of the embodiments,
The 30%~50% of degree.Further, all the gross area of the blind holes be the wall material outer surface area 20%~
80%, for example, all the gross area of the blind hole is the 40%~60% of the area of the outer surface of the wall material;For example, all
The gross area of the blind hole is the 50% of the area of the outer surface of the wall material.It is all described blind for different product demands
There is some difference for the ratio of the area of the outer surface of the gross area in hole and the wall material, for example, for needing to burst out rapidly
Cosmetics, the large percentage of the gross area and the area of the outer surface of the wall material of whole blind holes, for example, all described blind
The gross area in hole is the 50%~80% of the area of the outer surface of the wall material;For the cosmetics that need not be burst out rapidly, entirely
The ratio of the area of the outer surface of the gross area of blind hole described in portion and the wall material is smaller, for example, all total faces of the blind hole
Product is the 20%~50% of the area of the outer surface of the wall material.For the ease of rupturing rapidly, institute in one of the embodiments,
It states microsphere structure and offers at least three crank slots in the wall material, for example, each mutually isolated setting of the crank slot, i.e., each song
Slot is non-cross;For example, the crank slot is that either V-arrangement, that is, crank slot has wavy cross-section or V-arrangement section to waveform;
For another example, spacing having the same between adjacent two crank slots.Further, the wall material has in one of the embodiments,
There is wall portion, and each blind hole is uniformly distributed in the wall portion.For example, the microsphere structure is in the wall of the wall material
Portion offers at least three crank slots.Each blind hole is set on the outer surface of the wall portion in one of the embodiments,.Into one
Step ground, each blind hole are evenly distributedly set on the outer surface of the wall portion.Further, the chitosan in the blind hole
Mass ratio is higher than the chitosan mass ratio in the wall portion.For example, the wall portion includes that sodium alginate, calcium chloride and shell are poly-
Sugar, wherein sodium alginate, calcium chloride and chitosan mass ratio are " 2~5 ":" 0.5~1.5 ":" 1~6 ", and the blind hole
It is " 2~5 " including mass ratio:The sodium alginate and chitosan of " 1~6 ";For example, the wall portion includes sodium alginate, chlorination
Calcium and chitosan, wherein sodium alginate, calcium chloride and chitosan mass ratio are 3:0.5:6, and the blind hole includes mass ratio
Example is 2:5 sodium alginate and chitosan;Such structure design so that the microsphere structure of the composition is in stress
When can be oriented to rupture in an orderly manner, to prior to blind hole position with the higher various components disengaged with bursting out speed in core material, then
From wall portion rupture location to disengage the remaining ingredient in core material compared with low velocity, so as to make the microsphere structure different
Cosmetics have various magical effects, this is that the cosmetics of existing various homogeneous outputs cannot achieve.
Further, the wall portion offers spaced main nacelle and at least two in one of the embodiments,
Auxiliary nacelle, the main nacelle house the maximum component of accounting in the core material, and an auxiliary nacelle houses the shark in the core material
Liver alcohol isostearate, remaining auxiliary nacelle house remaining component in the core material respectively;It is appreciated that for remaining auxiliary cabin
Body, the mode that the accommodating various ingredients of an auxiliary nacelle may be used are realized.Further, the main nacelle and each auxiliary cabin
The thickness of bulkhead between body is less than the thickness of the wall portion, and the thickness for being similar to the outside wall portions of spaceship or steamer is more than cabin
Thickness between room;Further, the thickness of the bulkhead is less than the thickness of the outer wall of the blind hole, and the outer wall of the blind hole
Thickness be less than the wall portion thickness;In this way, when user uses the composition, such as composition generation extruding,
When massage or coating, the bulkhead first ruptures, and then each component of the core material carries out a degree of mixing, then
It disengages again;For example, when user uses the composition, each component that the core material first occurs to rupture for bulkhead carries out to a certain degree
Mixing, then the rupture of blind hole position is with the higher various components disengaged with bursting out speed in core material, rear wall parts rupture and with
The remaining ingredient in core material is disengaged compared with low velocity ,-is burst out-so as to form mixing and is delayed the mode and disengage component in core material.
For example, it is " 2~5 " that the bulkhead, which includes mass ratio,:The sodium alginate and chitosan of " 1~6 ";Further, the bulkhead
It is 3 including mass ratio:5 or 2:5 sodium alginate and chitosan.Further, the wall in one of the embodiments,
Portion offers spaced main nacelle and two auxiliary nacelles, and the main nacelle houses the maximum component of accounting in the core material,
The one auxiliary nacelle houses the batyl alcohol isostearate in the core material, and another auxiliary nacelle houses its in the core material
Remaining component.Further, the wall portion offers spaced main nacelle and at least two auxiliary in one of the embodiments,
Nacelle, the main nacelle house the water in the core material, and an auxiliary nacelle houses the batyl alcohol isostearic acid in the core material
Ester, remaining auxiliary nacelle house remaining component in the core material respectively;For example, the wall portion is opened in one of the embodiments,
Equipped with spaced main nacelle and two auxiliary nacelles, the main nacelle houses the water in the core material, and an auxiliary nacelle is held
The batyl alcohol isostearate in the core material is set, another auxiliary nacelle houses remaining component in the core material.In this way, can
It to realize that finish is stored respectively with aqua, remixes when in use, so as to greatly promote effective use of active principle
Phase.For example, the wall portion offers spaced main nacelle and three auxiliary nacelles, the master in one of the embodiments,
Nacelle houses the water in the core material, and an auxiliary nacelle houses the batyl alcohol isostearate in the core material, another described
Auxiliary nacelle houses the remaining ingredient of the intermixture in addition to water, and a remaining auxiliary nacelle houses the core material respectively
In remaining component;Remaining embodiment and so on.For example, each auxiliary nacelle is symmetrical arranged, such as when there are two auxiliary cabins
When body, two auxiliary nacelle axial symmetry settings, when there are three auxiliary nacelles, three auxiliary nacelle center symmetric settings or three it is auxiliary
Nacelle figure in a center of symmetry on a certain section.For another example, the main nacelle is located at the middle part of the microsphere structure, i.e., described
Main nacelle is located at the middle part of the wall portion, and further, each auxiliary nacelle is symmetrical arranged relative to the main nacelle.
Further, the blind hole closed-loop layout and microsphere structure is in institute in one of the embodiments,
It states and is formed with inner chamber body in blind hole, also that is, the blind hole is the structure that inside closed at both ends is cavity.For example, placenta stem-cell
0.02~0.05 part is respectively arranged in the inner chamber body of each blind hole, for example, using injection or air pump mode by tire
0.02~0.05 part of disk stem cell is respectively arranged in the inner chamber body of each blind hole.For example, between the wall portion offers
Every the main nacelle and at least two auxiliary nacelles of setting, the main nacelle houses the maximum component of accounting in the core material, and placenta is dry
0.02~0.05 part of cell is respectively arranged in the inner chamber body of each blind hole, and an auxiliary nacelle houses in the core material
Batyl alcohol isostearate, remaining auxiliary nacelle houses remaining component in the core material respectively;For another example, the wall portion offers
Spaced main nacelle and two auxiliary nacelles, the main nacelle house the water in the core material, and placenta stem-cell 0.02~
0.05 part is respectively arranged in the inner chamber body of each blind hole, and the batyl alcohol that an auxiliary nacelle houses in the core material is different
Stearate, another auxiliary nacelle house remaining component in the core material;For another example, the wall portion offers spaced
Main nacelle and three auxiliary nacelles, the main nacelle house the water in the core material, and 0.02~0.05 part of placenta stem-cell is set respectively
It is placed in the inner chamber body of each blind hole, an auxiliary nacelle houses the batyl alcohol isostearate in the core material, separately
The one auxiliary nacelle houses the remaining ingredient of the intermixture in addition to water, and a remaining auxiliary nacelle houses institute respectively
State remaining component in core material;Remaining embodiment and so on.In this way, being conducive to preferably protect the placenta stem-cell, make
Placenta stem-cell keeps activity time longer, this is also that the cosmetics of existing various homogeneous output cannot achieve.
Application of the composition including batyl alcohol isostearate in cosmetics described in any embodiment.A reality wherein
It applies in example, the cosmetics include lipstick, massage cream, facial mask, facial cleanser, skin care milk, reparation breast, toner or skin cream etc..
For example, the cosmetics are lipstick, the wall material rupture of microsphere structure, disengages internal core material when stress;For another example, the makeup
Product are facial mask, and the wall material rupture of part microsphere structure, disengages internal core material, again stress from certain orientation when first stress
When more microsphere structures wall material rupture, continue supplement and disengage internal core material, to the beautification function time it is long and
Two long advantages of long shelf-life.Other cosmetics and so on, it repeats no more.
It continues with and provides several specific embodiments the present invention will be described.
Embodiment 1:Include the composition of batyl alcohol isostearate comprising several microsphere structures, wherein described micro-
Sphere structure includes wall material and core material, and the wall material coats the core material;The wherein described core material includes the group of following mass fraction
Point:60 parts of 6 parts of batyl alcohol isostearate, 0.02 part of placenta stem-cell and intermixture;Wherein, the intermixture includes water,
The wall material includes sodium alginate.
Embodiment 2:Include the composition of batyl alcohol isostearate comprising several microsphere structures, wherein described micro-
Sphere structure includes wall material and core material, and the wall material coats the core material;The wherein described core material includes the group of following mass fraction
Point:56 parts of 3 parts of batyl alcohol isostearate, 0.04 part of placenta stem-cell and intermixture;Wherein, the intermixture includes quality
Ratio is 1:2:3:50 amino acid surfactant, emulsifier, moisturizer and water, the amino acid surfactant include matter
Amount ratio is 1:1 sodium lauroyl glutamate and myristoyl glutamate sodium, the emulsifier include that mass ratio is 2:1:1
Glycerol monolaurate, dilaurin and glycerine myristate ester, the emulsifier include that mass ratio is 5:1 it is transparent
Matter acid and ceramide, the wall material include that mass ratio is 3:0.5:6 sodium alginate, calcium chloride and chitosan.
Embodiment 3:Include the composition of batyl alcohol isostearate comprising several microsphere structures, wherein described micro-
Sphere structure includes wall material and core material, and the wall material coats the core material;The wherein described core material includes the group of following mass fraction
Point:4 parts of batyl alcohol isostearate, 0.2 part of Bai Shi ash jasmines flower extract, 0.4 part of Spiraea ulmaria leaf extract, corn poppy's petal
0.3 part of extract, 0.2 part of golden hairpin dendrobium extract, 1 part of glycine, 0.5 part of proline, 0.75 part of alanine, threonine 0.75
Part, 1 part of valine, 1 part of leucine, 0.75 part of histidine, 0.05 part of placenta stem-cell and 74 parts of intermixture;Wherein, described
Intermixture includes that mass ratio is 1.5:2.5:4:66 amino acid surfactant, emulsifier, moisturizer and water, the amino
Acid surfaces activating agent includes that mass ratio is 1:2:1:0.8 sodium lauroyl glutamate, myristoyl glutamate sodium, cocoyl
Glutamic acid triethanolamine salt and sodium methyl cocoyl taurate, the emulsifier include that mass ratio is 0.6:2.5:2.5:
The 2.5 smooth oleate of sorb, glycerol monolaurate, dilaurin and glycerine myristate ester, the moisturizer include
Mass ratio is 14:1 glycerine and hyaluronic acid, the wall material include that mass ratio is 2:1:4 sodium alginate, calcium chloride
With chitosan.
Comparative example 1:Certain commercially available facial mask.
Comparative example 2:Certain commercially available lipstick.
Using 4 groups of volunteers, correspond to embodiment 1 to 3 and comparative example 1 to 2, respectively to hand skin and skin of face
It is persistently tried out, the results are shown in table below.
As seen from the above table, every test effect of embodiment 1 to 3 is superior to comparative example.
For example, a kind of preparation method of the composition including batyl alcohol isostearate, includes the following steps:By any reality
The each component mixing for applying the core material of the example composition only need to get out described group when needing to split Shi Yike not mixings
Close each component of the core material of object.For another example, by after each component mixing of composition described in any embodiment, the system
Preparation Method is further comprising the steps of:Encapsulation;Alternatively, being directly packaged, i.e., directly it is packaged without mixing.For example, pressing wall
Material capacity packaging is in wall material.For another example, by after each component mixing of composition described in any embodiment, and wall material capacity is pressed
Before being encapsulated in wall material, the preparation method is further comprising the steps of:It stands;For example, standing 24~240 hours.In this way, root
According to the different component of composition described in any embodiment, the composition corresponding to any embodiment can be made.
It should be noted that in each embodiment, Spiraea ulmaria leaf extract, the i.e. extract of the leaf of Spiraea ulmaria can be with
It is obtained by making by oneself or buying commercial product, remaining component and remaining embodiment and so on.For another example, in each embodiment, shark
Liver alcohol isostearate is to make or buy commercially available batyl alcohol isostearate by oneself.It is appreciated that the present invention and its each embodiment
Extract, including be not limited to Bai Shi ash jasmines flower extract, Spiraea ulmaria leaf extract, corn poppy's petal extract and/or
Golden hairpin dendrobium extract etc. in practical operation, may be used the chemical reagent such as aqua, alcohol agent or ether agent and combine squeezing, squeeze juice, extraction
Take, centrifuge either the physics modes such as distillation extraction concentration according to demand or experiment deployment, for example, extract can be
Solid particle or liquid, of the invention and its each embodiment do not do this additional limitation, and preferably extract is that grain size is micro- less than 25
The powdery granule of rice, you can be sieved by 500 mesh, in this way, the active ingredient of composition described in the present invention and its each embodiment
Molecule it is very small, skin surface can be penetrated and deeply moisten maintenance skin, and designed, can be obtained by reasonable component proportion
Preferable cosmetics using effect.
It should be noted that in each embodiment, described part, i.e. mass parts, that is, mass fraction, it can be understood as gram, milli
Gram, kilogram, jin, kilogram, pound, ton etc..By gram for, for example, 1 part is a certain quality in 0.0001 to 10000 gram;Example
Such as, 1 part can be 0.001g, 0.01g, 0.02g, 0.05g, 0.1g, 0.2g, 0.5g, 1g, 2g, 3g, 4g, 5g, 10g, 15g,
20g, 30g, 50g, 80g, 100g, 500g, 1000g, 5000g, 10000g or 50000g etc., and it is without being limited thereto, according to practical life
Production manufacture is selected, each embodiment and so on.For example, 1 part is 1 gram, 0.1 part is 0.1 gram;For another example, 1 part is 10 grams,
0.1 part is 1 gram;For another example, 1 part is 100 grams, and 0.1 part is 10 grams;And so on.It in a particular application can be according to practical need
Seek flexible design, it is only necessary to meet the certain mass proportioning or mass ratio of each component.
Further, other embodiments of the invention further include that the technical characteristic in the various embodiments described above is combined with each other institute
Composition including batyl alcohol isostearate being formed, can implementing and its in the application of cosmetics and its in cosmetics
Using;In each embodiment, the composition is also referred to as cosmetic composition or cosmetics, that is, described includes that batyl alcohol is different hard
The composition of resin acid ester includes also referred to as the cosmetic composition of batyl alcohol isostearate or including batyl alcohol isostearic acid
The cosmetics of ester.
Each technical characteristic of embodiment described above can be combined arbitrarily, to keep description succinct, not to above-mentioned reality
It applies all possible combination of each technical characteristic in example to be all described, as long as however, the combination of these technical characteristics is not deposited
In contradiction, it is all considered to be the range of this specification record.
Several embodiments of the invention above described embodiment only expresses, the description thereof is more specific and detailed, but simultaneously
It cannot therefore be construed as limiting the scope of the patent.It should be pointed out that coming for those of ordinary skill in the art
It says, without departing from the inventive concept of the premise, various modifications and improvements can be made, these belong to the protection of the present invention
Range.Therefore, the protection domain of patent of the present invention should be determined by the appended claims.
Claims (10)
1. a kind of composition including batyl alcohol isostearate, which is characterized in that including several microsphere structures, wherein institute
It includes wall material and core material to state microsphere structure, and the wall material coats the core material;The wherein described core material includes following mass fraction
Component:43~96 parts of 2.5~6 parts of batyl alcohol isostearate, 0.02~0.05 part of placenta stem-cell and intermixture.
2. composition according to claim 1, which is characterized in that the wall material includes that sodium alginate, calcium chloride and/or shell are poly-
Sugar.
3. composition according to claim 1, which is characterized in that the wall material includes sodium alginate, calcium chloride and chitosan,
Wherein, sodium alginate, calcium chloride and chitosan mass ratio are " 2~5 ":" 0.5~1.5 ":" 1~6 ".
4. composition according to claim 1, which is characterized in that the microsphere structure is provided at least ten in the wall material
Blind hole.
5. composition according to claim 4, which is characterized in that each blind hole is uniformly distributed in the wall material.
6. composition according to claim 5, which is characterized in that each blind hole is set on the outer surface of the wall material.
7. composition according to claim 6, which is characterized in that the depth of the blind hole is the thickness of the wall portion of the wall material
30%~50%.
8. composition according to claim 1, which is characterized in that the microsphere structure offers at least three in the wall material
Crank slot.
9. according to any one of claim 1 to 8 composition, which is characterized in that the intermixture includes water, surface-active
Agent, emulsifier and moisturizer, wherein surfactant, emulsifier, moisturizer and water mass ratio be " 1~2 ":" 2~5 ":
" 1~5 ":" 31~93 ".
10. according to any one of claim 1 to 9 composition cosmetics application.
Priority Applications (1)
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CN201810316007.2A CN108403615A (en) | 2018-04-10 | 2018-04-10 | Composition including batyl alcohol isostearate and its application in cosmetics |
Applications Claiming Priority (1)
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CN201810316007.2A CN108403615A (en) | 2018-04-10 | 2018-04-10 | Composition including batyl alcohol isostearate and its application in cosmetics |
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Family
ID=63135062
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CN201810316007.2A Withdrawn CN108403615A (en) | 2018-04-10 | 2018-04-10 | Composition including batyl alcohol isostearate and its application in cosmetics |
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Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1272783A (en) * | 1997-09-01 | 2000-11-08 | 布茨公司 | Dermatological compositions |
CN103446029A (en) * | 2012-05-28 | 2013-12-18 | 孙勇 | Umbilical placental stem cell technology for cosmetic skin care product |
CN105213283A (en) * | 2015-10-30 | 2016-01-06 | 重庆小丸科贸有限公司 | A kind of bright eye cream of microcapsule-type |
-
2018
- 2018-04-10 CN CN201810316007.2A patent/CN108403615A/en not_active Withdrawn
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1272783A (en) * | 1997-09-01 | 2000-11-08 | 布茨公司 | Dermatological compositions |
CN103446029A (en) * | 2012-05-28 | 2013-12-18 | 孙勇 | Umbilical placental stem cell technology for cosmetic skin care product |
CN105213283A (en) * | 2015-10-30 | 2016-01-06 | 重庆小丸科贸有限公司 | A kind of bright eye cream of microcapsule-type |
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