CN108403455A - A method of it doing inorganic antibacterial filler with diatomite and makes toothpaste - Google Patents
A method of it doing inorganic antibacterial filler with diatomite and makes toothpaste Download PDFInfo
- Publication number
- CN108403455A CN108403455A CN201810584838.8A CN201810584838A CN108403455A CN 108403455 A CN108403455 A CN 108403455A CN 201810584838 A CN201810584838 A CN 201810584838A CN 108403455 A CN108403455 A CN 108403455A
- Authority
- CN
- China
- Prior art keywords
- diatomite
- purification
- toothpaste
- bacterium
- antibacterial
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 title claims abstract description 79
- 230000000844 anti-bacterial effect Effects 0.000 title claims abstract description 30
- 229940034610 toothpaste Drugs 0.000 title claims abstract description 23
- 239000000606 toothpaste Substances 0.000 title claims abstract description 23
- 238000000034 method Methods 0.000 title claims abstract description 18
- 239000000945 filler Substances 0.000 title claims abstract description 8
- 238000000746 purification Methods 0.000 claims abstract description 15
- 239000002245 particle Substances 0.000 claims abstract description 14
- 230000008569 process Effects 0.000 claims abstract description 10
- 238000000605 extraction Methods 0.000 claims abstract description 7
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 claims description 21
- 239000002689 soil Substances 0.000 claims description 9
- 239000008187 granular material Substances 0.000 claims description 8
- 238000009991 scouring Methods 0.000 claims description 8
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 8
- 239000004927 clay Substances 0.000 claims description 6
- 239000000725 suspension Substances 0.000 claims description 6
- 229910044991 metal oxide Inorganic materials 0.000 claims description 5
- 150000004706 metal oxides Chemical class 0.000 claims description 5
- 238000004062 sedimentation Methods 0.000 claims description 5
- 238000001556 precipitation Methods 0.000 claims description 4
- 239000007864 aqueous solution Substances 0.000 claims description 3
- 238000001354 calcination Methods 0.000 claims description 3
- 239000002270 dispersing agent Substances 0.000 claims description 3
- 238000001035 drying Methods 0.000 claims description 3
- 239000004576 sand Substances 0.000 claims description 3
- 238000004513 sizing Methods 0.000 claims description 3
- 125000002091 cationic group Chemical group 0.000 claims description 2
- 229920000620 organic polymer Polymers 0.000 claims description 2
- 238000007873 sieving Methods 0.000 claims description 2
- 239000000377 silicon dioxide Substances 0.000 claims description 2
- 238000005406 washing Methods 0.000 claims description 2
- 240000007594 Oryza sativa Species 0.000 claims 1
- 235000007164 Oryza sativa Nutrition 0.000 claims 1
- 235000009566 rice Nutrition 0.000 claims 1
- 241000894006 Bacteria Species 0.000 abstract description 26
- 210000002421 cell wall Anatomy 0.000 abstract description 7
- 229910052500 inorganic mineral Inorganic materials 0.000 abstract description 6
- 239000011707 mineral Substances 0.000 abstract description 6
- 238000010521 absorption reaction Methods 0.000 abstract description 5
- 239000000463 material Substances 0.000 abstract description 5
- 210000000170 cell membrane Anatomy 0.000 abstract description 4
- 206010003497 Asphyxia Diseases 0.000 abstract description 3
- 230000015572 biosynthetic process Effects 0.000 abstract description 2
- 230000002147 killing effect Effects 0.000 abstract description 2
- 230000004048 modification Effects 0.000 abstract description 2
- 238000012986 modification Methods 0.000 abstract description 2
- 239000002994 raw material Substances 0.000 abstract description 2
- 230000001954 sterilising effect Effects 0.000 abstract description 2
- 239000000126 substance Substances 0.000 abstract description 2
- 230000002195 synergetic effect Effects 0.000 abstract description 2
- 238000003786 synthesis reaction Methods 0.000 abstract description 2
- 230000005611 electricity Effects 0.000 description 9
- 239000004615 ingredient Substances 0.000 description 6
- 230000000694 effects Effects 0.000 description 5
- 238000012360 testing method Methods 0.000 description 5
- CDBYLPFSWZWCQE-UHFFFAOYSA-L Sodium Carbonate Chemical compound [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 description 4
- 239000002734 clay mineral Substances 0.000 description 4
- 230000008901 benefit Effects 0.000 description 3
- 150000001768 cations Chemical class 0.000 description 3
- 239000007789 gas Substances 0.000 description 3
- 239000007788 liquid Substances 0.000 description 3
- 239000002244 precipitate Substances 0.000 description 3
- FRXSZNDVFUDTIR-UHFFFAOYSA-N 6-methoxy-1,2,3,4-tetrahydroquinoline Chemical compound N1CCCC2=CC(OC)=CC=C21 FRXSZNDVFUDTIR-UHFFFAOYSA-N 0.000 description 2
- 241000233866 Fungi Species 0.000 description 2
- BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical compound [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 description 2
- 229910002808 Si–O–Si Inorganic materials 0.000 description 2
- 241000194019 Streptococcus mutans Species 0.000 description 2
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 description 2
- 239000002253 acid Substances 0.000 description 2
- 238000004140 cleaning Methods 0.000 description 2
- 239000000470 constituent Substances 0.000 description 2
- 238000004090 dissolution Methods 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 230000002964 excitative effect Effects 0.000 description 2
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 2
- 239000010931 gold Substances 0.000 description 2
- 229910052737 gold Inorganic materials 0.000 description 2
- 150000002500 ions Chemical class 0.000 description 2
- 229910052751 metal Inorganic materials 0.000 description 2
- 239000002184 metal Substances 0.000 description 2
- 210000000214 mouth Anatomy 0.000 description 2
- 239000005416 organic matter Substances 0.000 description 2
- 239000000047 product Substances 0.000 description 2
- 229910052709 silver Inorganic materials 0.000 description 2
- 239000004332 silver Substances 0.000 description 2
- 239000002002 slurry Substances 0.000 description 2
- 229910000029 sodium carbonate Inorganic materials 0.000 description 2
- 238000001179 sorption measurement Methods 0.000 description 2
- 238000003756 stirring Methods 0.000 description 2
- 231100000331 toxic Toxicity 0.000 description 2
- 230000002588 toxic effect Effects 0.000 description 2
- 229910052725 zinc Inorganic materials 0.000 description 2
- 239000011701 zinc Substances 0.000 description 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 1
- 241000195493 Cryptophyta Species 0.000 description 1
- 241000790917 Dioxys <bee> Species 0.000 description 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 description 1
- 235000006508 Nelumbo nucifera Nutrition 0.000 description 1
- 240000002853 Nelumbo nucifera Species 0.000 description 1
- 235000006510 Nelumbo pentapetala Nutrition 0.000 description 1
- 239000004113 Sepiolite Substances 0.000 description 1
- 229910003978 SiClx Inorganic materials 0.000 description 1
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 description 1
- 229910021536 Zeolite Inorganic materials 0.000 description 1
- 230000002421 anti-septic effect Effects 0.000 description 1
- 229910052799 carbon Inorganic materials 0.000 description 1
- JYYOBHFYCIDXHH-UHFFFAOYSA-N carbonic acid;hydrate Chemical compound O.OC(O)=O JYYOBHFYCIDXHH-UHFFFAOYSA-N 0.000 description 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- GUJOJGAPFQRJSV-UHFFFAOYSA-N dialuminum;dioxosilane;oxygen(2-);hydrate Chemical compound O.[O-2].[O-2].[O-2].[Al+3].[Al+3].O=[Si]=O.O=[Si]=O.O=[Si]=O.O=[Si]=O GUJOJGAPFQRJSV-UHFFFAOYSA-N 0.000 description 1
- LZBIYPIDWSGLOV-UHFFFAOYSA-N dimethyl(prop-2-enyl)azanium;chloride Chemical compound [Cl-].C[NH+](C)CC=C LZBIYPIDWSGLOV-UHFFFAOYSA-N 0.000 description 1
- HNPSIPDUKPIQMN-UHFFFAOYSA-N dioxosilane;oxo(oxoalumanyloxy)alumane Chemical compound O=[Si]=O.O=[Al]O[Al]=O HNPSIPDUKPIQMN-UHFFFAOYSA-N 0.000 description 1
- 125000005313 fatty acid group Chemical group 0.000 description 1
- 238000009775 high-speed stirring Methods 0.000 description 1
- 229910052739 hydrogen Inorganic materials 0.000 description 1
- 239000001257 hydrogen Substances 0.000 description 1
- 229910010272 inorganic material Inorganic materials 0.000 description 1
- 239000011147 inorganic material Substances 0.000 description 1
- 125000003010 ionic group Chemical group 0.000 description 1
- 239000010410 layer Substances 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 239000002207 metabolite Substances 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 229910052901 montmorillonite Inorganic materials 0.000 description 1
- PZNOBXVHZYGUEX-UHFFFAOYSA-N n-prop-2-enylprop-2-en-1-amine;hydrochloride Chemical compound Cl.C=CCNCC=C PZNOBXVHZYGUEX-UHFFFAOYSA-N 0.000 description 1
- 239000001814 pectin Substances 0.000 description 1
- 235000010987 pectin Nutrition 0.000 description 1
- 229920001277 pectin Polymers 0.000 description 1
- 230000000505 pernicious effect Effects 0.000 description 1
- 125000002467 phosphate group Chemical group [H]OP(=O)(O[H])O[*] 0.000 description 1
- 239000011148 porous material Substances 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 230000029058 respiratory gaseous exchange Effects 0.000 description 1
- 229910052624 sepiolite Inorganic materials 0.000 description 1
- 235000019355 sepiolite Nutrition 0.000 description 1
- 229910052710 silicon Inorganic materials 0.000 description 1
- 239000010703 silicon Substances 0.000 description 1
- 235000012239 silicon dioxide Nutrition 0.000 description 1
- 239000002356 single layer Substances 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 238000013268 sustained release Methods 0.000 description 1
- 239000012730 sustained-release form Substances 0.000 description 1
- 239000010457 zeolite Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/25—Silicon; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/70—Biological properties of the composition as a whole
- A61K2800/72—Hypo-allergenic
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Inorganic Chemistry (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Cosmetics (AREA)
Abstract
It is the present invention relates to daily use chemicals field of toothpaste, i.e., a kind of to make the method that inorganic antibacterial filler makes toothpaste of diatomite.Its step are as follows：1, Purification of Diatomite：（1）Purification is cleaned,（2）Roasting purification,（3）Grading extraction.2, diatomite modified arranges.Diatomite particle surface after modification is changed into electropositive by original elecrtonegativity, it was confirmed that the completion of surface charge modifying process；For raw material of toothpaste, it is conducive to bacterium asphyxia, rupture, achievees the purpose that antibacterial, antibacterial.Cell wall, the cell membrane of intraoral bacterium are negative, diatom inorganic antibacterial material positive charge can from medium the negatively charged bacterium of a large amount of absorption surfaces, it is supression and the killing effect of the ion pair bacterium of mineral release, its antibacterial efficacy is the synthesis result of Electrostatic Absorption and ion sterilizing ability synergistic effect.
Description
Technical field
It is the present invention relates to daily use chemicals field of toothpaste, i.e., a kind of to make the method that inorganic antibacterial filler makes toothpaste of diatomite.
Background technology
In the prior art, diatomite is a kind of novel environment-friendly materials, it has the pernicious gas in air relatively strong
Adsorption capacity and other functions, be applied to the daily life such as various products, craftwork by people due to its own distinctive function
It applies flexibly in product.Purification both at home and abroad at present, modified, production the general surface of diatomite are all negatively charged, and electric potential value is
Negative value.
Inorganic antibacterial toothpaste refers to the one kind added inorganic antibacterial ingredient, bacterium is killed or inhibited using the method for physics
Toothpaste.Cell wall, the cell membrane of most of harmful bacteria are negative, and the metal cations such as gold, silver, zinc can be by positive and negative attracting
And make bacterium asphyxia, rupture, generate " dissolution phenomena ", achieve the purpose that antibacterial, antibacterial；Sepiolite, montmorillonite, zeolite, activity
The inorganic material such as carbon are to do the metal cations such as carrier loaded gold, silver, zinc, and sustained release is reached by way of adsorbing, wrapping up and is released
Put the purpose of removal bacterium.
These inorganic antibacterial ingredients are added in toothpaste, relative to addition organic chemistry antibacterial and traditional Chinese medicine ingredients, have it is long-acting,
It is excitatory it is small, toxic side effect is small, does not generate the characteristics of antibody-resistant bacterium.
The technology that inorganic antibacterial toothpaste is directly prepared using diatomite as active constituent not yet occurs, and with the modified diatom of addition
Soil is the toothpaste of inorganic antibacterial material by having not been reported as antiseptic toothpaste.
Invention content
The purpose of the present invention is provide against the above deficiency and a kind of doing inorganic antibacterial filler with diatomite and make toothpaste
Method is added to diatom inorganic antibacterial ingredient in toothpaste, solves the problems, such as not generate antibody-resistant bacterium in oral cavity.Relative to addition
For the toothpaste of organic chemistry antibacterial and traditional Chinese medicine ingredients, diatom inorganic antibacterial ingredient have it is long-acting, excitatory it is small, toxic side effect is small
Advantage.
Technical solution of the invention is：A method of it doing inorganic antibacterial filler with diatomite and makes toothpaste, it is special
Sign is that steps are as follows：
1, it is high-quality pure white that the source counties Chang Bai are selected from, diatomite of the amorphous silica content not less than 86% is purified：
（1）Clean purification：Diatomite original soil is soaked in water 1~2 h, then by adding water and dispersant（Such as sodium carbonate）, make material
Slurry concentration reaches 30%, and stirs scouring, and the process of scouring is exactly to be rinsed using high-velocity flow, makes detrital mineral and clay mineral
It is detached with diatom, precipitation is shaked out respectively, and slightly soil, suspension grade clay and Primary Study of Choosing Diatomite, Primary Study of Choosing Diatomite reach unformed dioxy to grade
90% or more SiClx；It cleans 3 times repeatedly, cleans time about 20~30min, thick native, suspension grade clay the precipitation of each sand grade every time
Time is 4~6min, and the sedimentation time of last time Primary Study of Choosing Diatomite is 2~4h；By cleaning, detrital mineral and clay mineral
It is removed, diatom is opposite to be enriched with, Si02Content improves, Al2 03、Fe2 03Content reduces, the diatom granule content in diatomite
Reach 92%.
（2）Roasting purification：Sodium hydroxide is added to roast the Primary Study of Choosing Diatomite of scouring, roasting one is removal organic matter；
Second is that due to being added to sodium hydroxide, in roasting process, the metal oxide in diatomite reacts with sodium hydroxide, reaction
Object aggregate and precipitate, calcination temperature are 400~650 DEG C；Diatomite after roasting rejects the metal oxide of aggregate and precipitate through selection by winnowing,
The diatom granule content in diatomite is set to reach 98%.Diatom granule content is higher, and diatomaceous functionality is stronger.
（3）Grading extraction：Grading extraction is carried out with gas flow sizing machine to the diatomite after purification, take particle size interval be 15 ~
20 microns of diatom particles.The safety that diatomite is applied in toothpaste is improved, the size of particle determines the height of the gum extent of damage
It is low.
2, diatomite modified arranges：Diatomite and cationic organic polymer（Such as food-grade poly dimethyl allyl
Ammonium chloride）Aqueous solution mixes high-speed stirred, and 20~30min of high-speed stirred adjusts pH value 5-6.8, is conducive to antibacterial, antibacterial, then
Through the processes such as being filtered, washed, drying, crush, be sieved.It is changed to by the negative electricity on modified diatom particle positively charged.
It is an advantage of the invention that：
1, streptococcus mutans total number of bacteria 5.2 × 103A/ml does filler with the diatomite of organically-modified arrangement, making
Toothpaste is to bacteria test result；Bacteria-eliminating efficacy after organically-modified is more superior, can remove 99% or more bacterium.Test result table
Bright, its thinner potential value of granularity on positive electricity absorbent-type diatom is higher, then better to the removal function and effect of elecrtonegativity bacterium liquid.
2, the diatomite particle surface after modification is changed into electropositive by original elecrtonegativity, it was confirmed that surface charge
The completion of modifying process；For raw material of toothpaste, it is conducive to bacterium asphyxia, rupture, generates " dissolution phenomena ", reach antibacterial, antibacterial
Purpose.
3, the cell wall, cell membrane of intraoral bacterium are negative, and diatom inorganic antibacterial material positive charge can be from medium
In a large amount of negatively charged bacteriums of absorption surface, it is supression and the killing effect of the ion pair bacterium of mineral release, it
Antibacterial efficacy is the synthesis result of Electrostatic Absorption and ion sterilizing ability synergistic effect.
Embodiments of the present invention are described in further detail below in conjunction with embodiment.
Specific implementation mode
Embodiment 1
1, Purification of Diatomite
（1）Clean purification diatomite：Original soil 1~2 h that is soaked in water keeps slurry dense then by adding water and sodium carbonate dispersant
Degree reaches 30%, and stirs scouring, and the process of scouring is exactly to be rinsed using high-velocity flow, makes detrital mineral and clay mineral and silicon
Algae detaches, and precipitation is shaked out the thick soil of grade, suspension grade clay and Primary Study of Choosing Diatomite respectively, smart soil reach amorphous silica 90% with
On；Clean 3 times repeatedly, clean time about 20~30min every time, the thick soil of each sand grade, suspension grade clay sedimentation time be 4~
The sedimentation time of 6min, last time Primary Study of Choosing Diatomite are 2~4h；By cleaning, detrital mineral and clay mineral are removed,
Diatom is opposite to be enriched with, Si02Content improves, Al2 03、Fe2 03Content reduces, and the diatom granule content in diatomite reaches 92%.
（2）Roasting purification：Sodium hydroxide is added to roast in the diatomite of scouring, roasting one is removal organic matter；Second is that
Due to being added to sodium hydroxide, in roasting process, metal oxide is not cleaned in diatomite and is reacted with sodium hydroxide, instead
It is 400~650 DEG C to answer object aggregate and precipitate, calcination temperature；Diatomite after roasting rejects metal oxide through selection by winnowing, makes diatomite
In diatom granule content reach 98%.The diatom granule content in diatomite is set to reach 98% or more, diatom granule content is higher
Diatomaceous functionality is stronger.
（3）Grading extraction：Grading extraction is carried out with gas flow sizing machine to the diatomite after purification, take particle size interval be 15 ~
20 microns of diatom particles.Improve the safety that diatomite is applied in toothpaste（The size of particle determines the height of the gum extent of damage
It is low）
2, diatomite modified arranges：Diatomite mixes high-speed stirred, high-speed stirring with polydimethyl diallyl ammonium chloride aqueous solution
It mixes 20~30min, adjusts pH value 5-6.8, be conducive to antibacterial, antibacterial, using processes such as filter, washing, drying, crushing, sievings,
Organically-modified modified sample is made.The benefit of diatomite modified is：Negative electricity on diatom particle is changed to positively charged.
Experimental example
Current potential compares before and after diatomite modified（mV）：
Diatomaceous main component is aqueous non-quality silicon dioxide.Under ordinary circumstances, diatomite particle surface is negatively charged
Lotus.This is because the Si-O-Si keys and unbroken Si-O-Si keys of some fractures of diatomite surface can realize chemistry with water
Absorption forms the surface absorbed layer with oyl negative electricity groups, then passes through the Hydrogen Binding Adsorption hydrone on mono- layer of OH again：
The SiO on diatomite surface from another viewpoint2Molecule and water make surface before modified after diatomite potential measurement result.Through
Organically-modified treated diatomite, all obtains positive zeta potential value after tested, characterizes diatomite particle surface by original negative
Electrically it is changed into electropositive, it was confirmed that the completion of surface charge modifying process.
Add the test result of purifying modified diatomite toothpaste：There is a large amount of sun on diatomite through organically-modified arrangement, surface
Ionic group, since bacterium, fungi and cell membrane surface carry secondary charge, when it encounters these cation groups i.e. by
With, and then inhibit the breathing function of bacterium and lead to " contact is dead ", or change its surface charge number and generate " bacterolysis ", it is real
Now efficient degerming purpose.For microorganism with negative electricity because containing teichoic acid in cell wall constituent, phosphate group carries negative electricity, or
Person contains fatty acid chain and carries negative electricity, some fungies.For example there are many more the pectin objects being made of poly uronic acid in cell wall
Matter after carboxyl ionizes, makes cell wall carry many negative electrical charges.In short, thalline with negative electricity be due to cell wall composition at
Point having electronegative group, thalline itself can generate some metabolites and keep its negatively charged in other words.
Experimental example 2
It is derived from 5.2 × 10 3/ml of oral cavity streptococcus mutans total number of bacteria, diatomite carries out test result to bacterium and shows
Purifying modified diatomite has apparent difference to the effective of bacterium liquid.The diatomite of non-modified processing, due to pore
Retention, can remove the bacterium of part, but it is organically-modified after diatomite bacteria-eliminating efficacy it is superior, can cross remove 99% or more bacterium.
Test result shows that the granularity on positive electricity absorbent-type diatom is thinner and remittance potential value is higher, then to the effect of elecrtonegativity bacterium liquid
Better.
It is described above, only specific implementation mode of the invention, various illustrations are not to the substantive content structure of the present invention
At limitation.
Claims (1)
1. a kind of making the method that inorganic antibacterial filler makes toothpaste of diatomite, it is characterised in that steps are as follows：
Purification of Diatomite
（1）Clean purification：Diatomite original soil 1~2 h that is soaked in water makes pulp density reach then by adding water and dispersant
30%, and scouring is stirred, precipitation is shaked out respectively, and slightly soil, suspension grade clay and Primary Study of Choosing Diatomite, Primary Study of Choosing Diatomite reach unformed to grade
90% or more silica；It cleans 3 times repeatedly, cleans time about 20~30min every time, each sand grade is thick native, suspension grade clay
Sedimentation time is 4~6min, and the sedimentation time of last time Primary Study of Choosing Diatomite is 2~4h；
（2）Roasting purification：Sodium hydroxide is added to roast the Primary Study of Choosing Diatomite of scouring, calcination temperature is 400~650 DEG C；Roasting
Diatomite after burning rejects metal oxide through selection by winnowing, and the diatom granule content in diatomite is made to reach 98%；
（3）Grading extraction：Grading extraction is carried out with gas flow sizing machine to the diatomite after purification, it is 15 ~ 20 micro- to take particle size interval
Rice diatom particle；
Diatomite modified arranges：Diatomite mixes high-speed stirred with cationic organic polymer aqueous solution, and high-speed stirred 20~
30min, regulation system pH value 5-6.8 are made organically-modified modified using filter, washing, drying, crushing, sieving process
Product.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810584838.8A CN108403455B (en) | 2018-06-08 | 2018-06-08 | Method for preparing toothpaste by using diatomite as inorganic antibacterial filler |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810584838.8A CN108403455B (en) | 2018-06-08 | 2018-06-08 | Method for preparing toothpaste by using diatomite as inorganic antibacterial filler |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN108403455A true CN108403455A (en) | 2018-08-17 |
| CN108403455B CN108403455B (en) | 2020-12-18 |
Family
ID=63141476
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810584838.8A Active CN108403455B (en) | 2018-06-08 | 2018-06-08 | Method for preparing toothpaste by using diatomite as inorganic antibacterial filler |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN108403455B (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110326778A (en) * | 2019-07-13 | 2019-10-15 | 林聪� | Purposes of the diatomite in preparation removal helicobacter pylori food |
| CN111040339A (en) * | 2019-12-27 | 2020-04-21 | 山东霞光集团有限公司 | Diatom ooze wood-plastic wallboard and preparation method thereof |
| CN111840194A (en) * | 2020-08-13 | 2020-10-30 | 广州市名俐日用化工有限公司 | Whitening and stain-removing toothpaste containing diatomite and preparation method thereof |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101262907A (en) * | 2005-07-15 | 2008-09-10 | 高露洁-棕榄公司 | Oral coompositions having cationic active ingredients |
| CN101485617A (en) * | 2008-01-18 | 2009-07-22 | 邢津维 | Tooth-cleaning powder using bergmeal as raw material |
| CN102127319A (en) * | 2010-11-17 | 2011-07-20 | 王泽民 | Method for processing kieselguhr functional filler |
| CN103252209A (en) * | 2012-02-15 | 2013-08-21 | 任象玉 | Oil absorbent prepared from low grade diatomite and preparation method thereof |
| CN104162405A (en) * | 2014-07-15 | 2014-11-26 | 安徽省六安市朝晖机械制造有限公司 | Modified bentonite with bactericidal effect and preparation method thereof |
-
2018
- 2018-06-08 CN CN201810584838.8A patent/CN108403455B/en active Active
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101262907A (en) * | 2005-07-15 | 2008-09-10 | 高露洁-棕榄公司 | Oral coompositions having cationic active ingredients |
| CN101485617A (en) * | 2008-01-18 | 2009-07-22 | 邢津维 | Tooth-cleaning powder using bergmeal as raw material |
| CN102127319A (en) * | 2010-11-17 | 2011-07-20 | 王泽民 | Method for processing kieselguhr functional filler |
| CN103252209A (en) * | 2012-02-15 | 2013-08-21 | 任象玉 | Oil absorbent prepared from low grade diatomite and preparation method thereof |
| CN104162405A (en) * | 2014-07-15 | 2014-11-26 | 安徽省六安市朝晖机械制造有限公司 | Modified bentonite with bactericidal effect and preparation method thereof |
Non-Patent Citations (1)
| Title |
|---|
| 郑水林等: "《非金属矿加工技术与应用手册》", 31 May 2005, 冶金工业出版社 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110326778A (en) * | 2019-07-13 | 2019-10-15 | 林聪� | Purposes of the diatomite in preparation removal helicobacter pylori food |
| CN111040339A (en) * | 2019-12-27 | 2020-04-21 | 山东霞光集团有限公司 | Diatom ooze wood-plastic wallboard and preparation method thereof |
| CN111840194A (en) * | 2020-08-13 | 2020-10-30 | 广州市名俐日用化工有限公司 | Whitening and stain-removing toothpaste containing diatomite and preparation method thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| CN108403455B (en) | 2020-12-18 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN108403455A (en) | A method of it doing inorganic antibacterial filler with diatomite and makes toothpaste | |
| Unuabonah et al. | Novel metal-doped bacteriostatic hybrid clay composites for point-of-use disinfection of water | |
| CN103523969A (en) | Special apparatus for removing heavy metal ions in wastewater, and method thereof | |
| CN104941584A (en) | SiO2/C composite material for adsorbing heavy metal ions in water body and application thereof | |
| CN108671896A (en) | A kind of modified montmorillonite used and preparation method thereof, heavy metal chelating agent | |
| CN102895972A (en) | Method for preparing negative ion material used for organic pollutant and sewage treatment and having photo-catalysis performance | |
| CN106433338B (en) | A kind of coating and preparation method thereof | |
| CN101142921A (en) | Zeolite nanometer-zinc-oxide-loaded inorganic inhibiting sulfate reducing bacteria powder and its preparation method | |
| CN103911907B (en) | A kind of multicomponent alloy nano-oxide sterilizing and air filter paper and preparation method thereof | |
| Liu et al. | Amino-functionalized biomass-based aerogel derived from waste reed converted into an efficient photocatalyst after adsorption of Cu2+ | |
| CN110776079B (en) | Method for promoting phenol pollutants to be efficiently photo-catalytically oxidized in situ by utilizing organic arsenic pollutants | |
| CN106745610A (en) | Modification of chitosan carries the preparation of Zn complex and the application of removal ammonia nitrogen pollutant | |
| CN112618064B (en) | Invisible appliance and preparation method thereof | |
| DE102005005569A1 (en) | Heavy metal decontamination by hybrid biofilters | |
| CN102107907B (en) | Porous nano hydrated titanium dioxide dearsenifying material and preparation method thereof | |
| CN102487964B (en) | Bacteriostat for secondary breeding bacteria, preparation method thereof and purifier | |
| CN107670080A (en) | The method and apparatus that a kind of refrigerator removes peculiar smell sterilizing | |
| CN1840485A (en) | Water purifier for preparing high-energy active water | |
| CN109423642B (en) | Cu-Zn-ZnO composite material and preparation method and application thereof | |
| CN112624218A (en) | Mineral hydrogen-rich activation water purification filter element | |
| CN108658039B (en) | Water hydrogen production material and preparation method and application thereof | |
| CN111874918A (en) | Silica for toothpaste with anti-allergy and antibacterial effects and preparation method thereof | |
| CN206437981U (en) | It is a kind of to improve the healthy pen for drinking anion in water and air | |
| CN101948160B (en) | Composition capable of generating multiple kinds of energy and preparation method thereof | |
| Xu et al. | ZCS-TiO2 modified bacterial cellulose multifunctional membranes for highly effective and antibacterial oil-water separation |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| TA01 | Transfer of patent application right | ||
| TA01 | Transfer of patent application right |
Effective date of registration: 20201123 Address after: 134300 Six Groups of Red Sixth Committee of Hongqi Street, Badaojiang District, Baishan City, Jilin Province Applicant after: Diao Guangxiang Address before: 134300 Baishan City, Jilin Province, Hun Jiang District, 4 of the Jin Ying Village Street (Jiangbei Development Zone) Applicant before: JILIN FA DE LONG DIATOMITE NEW MATERIAL TECHNOLOGY Co.,Ltd. |
|
| GR01 | Patent grant | ||
| GR01 | Patent grant |