CN108392598A - A kind of ointment and preparation method thereof for treating tinea of feet and hands - Google Patents

A kind of ointment and preparation method thereof for treating tinea of feet and hands Download PDF

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CN108392598A
CN108392598A CN201810369240.7A CN201810369240A CN108392598A CN 108392598 A CN108392598 A CN 108392598A CN 201810369240 A CN201810369240 A CN 201810369240A CN 108392598 A CN108392598 A CN 108392598A
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parts
leaf
ointment
essential oil
feet
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不公告发明人
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/66—Papaveraceae (Poppy family), e.g. bloodroot
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    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/35—Fat tissue; Adipocytes; Stromal cells; Connective tissues
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    • A61K35/63—Arthropods
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    • A61K35/644—Beeswax; Propolis; Royal jelly; Honey
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    • A61K36/18—Magnoliophyta (angiosperms)
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/284—Atractylodes
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/32—Burseraceae (Frankincense family)
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
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    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/532—Agastache, e.g. giant hyssop
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704—Polygonum, e.g. knotweed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/74—Rubiaceae (Madder family)
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/906—Zingiberaceae (Ginger family)
    • A61K36/9066—Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
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    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/31—Extraction of the material involving untreated material, e.g. fruit juice or sap obtained from fresh plants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50—Methods involving additional extraction steps
    • A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying

Abstract

The present invention discloses a kind of ointment for treating tinea of feet and hands, includes the raw material of following parts by weight proportioning：70 79 parts of 28 33 parts of macleaya cordata leaf, 19 28 parts of madder leaf, 20 25 parts of turmeric leaf, 17 24 parts of littleflower plumbagella herb leaf, 58 parts of psoralea corylifolia fruit, 17 20 parts of teasel root, 49 parts of Armstrong, 20 22 parts of Rhizoma Atractylodis Macrocephalae, 13 parts of nano-calcium carbonate, 79 parts of sodium alginate, 10 12 parts of frankincense, 67 parts of oleanolic acid, 34 parts of Essential Oil From Pine Needles, 14 parts of Pogostemon cablin essential, 57 parts of deodar essential oil, 30 35 parts of honey and house oil, the therapeutic effect of the treatment tinea of feet and hands are good.

Description

A kind of ointment and preparation method thereof for treating tinea of feet and hands
Technical field
The present invention relates to a kind of ointment and preparation method thereof for treating tinea of feet and hands.
Background technology
Dermatophytosis refers mainly to the dermatophyte of close keratoprotein, includes mainly trichophyton, Microsporon and table Epidermophyton, invades the skin, hair, deck of humans and animals, and caused infection is referred to as dermatophytosis, abbreviation tinea.At present Dermatophytosis still presses site of pathological change and names such as favus of the scalp, ringworm of the body, jock itch, the tinea manuum, tinea pedis.Summer is multiple, and winter is rare.Mainly Pathogenic bacteria are dermatophytes, include mainly trichophyton, Microsporon and Epidermophyton, common feature is close cutin egg In vain, the skin, hair, deck for invading humans and animals, cause to infect.The fungi of the mankind is infected essentially from external environment, infection Approach can be contact, suck or eat.There are erythema, blister, the scales of skin that peel off, angling to thicken and the symptoms such as itch.
The external medication effect of current treatment tinea of feet and hands is general, it is hard to the needs of meeting in the market.
Invention content
The technical problem to be solved in the present invention is to provide a kind of ointment of the good treatment tinea of feet and hands of therapeutic effect and its preparations Method.
To solve the above problems, the present invention adopts the following technical scheme that：
A kind of ointment and preparation method thereof for treating tinea of feet and hands includes the raw material of following parts by weight proportioning：Macleaya cordata leaf 28-33 parts, 19-28 parts of madder leaf, 20-25 parts of turmeric leaf, 17-24 parts of littleflower plumbagella herb leaf, 5-8 parts of psoralea corylifolia fruit, teasel root 17-20 Part, 4-9 parts of Armstrong, 20-22 parts of Rhizoma Atractylodis Macrocephalae, 1-3 parts of nano-calcium carbonate, 7-9 parts of sodium alginate, 10-12 parts of frankincense, oleanolic acid 70-79 parts of 6-7 parts, 3-4 parts of Essential Oil From Pine Needles, 1-4 parts of Pogostemon cablin essential, 5-7 parts of deodar essential oil, 30-35 parts of honey and house oil.
Further, include the raw material of following parts by weight proportioning：28 parts of macleaya cordata leaf, 19 parts of madder leaf, turmeric leaf 20 Part, 17 parts of littleflower plumbagella herb leaf, 5 parts of psoralea corylifolia fruit, 17 parts of teasel root, 4 parts of Armstrong, 20 parts of Rhizoma Atractylodis Macrocephalae, 1 part of nano-calcium carbonate, sodium alginate 7 parts, 10 parts of frankincense, 6 parts of oleanolic acid, 3 parts of Essential Oil From Pine Needles, 1 part of Pogostemon cablin essential, 5 parts of deodar essential oil, 30 parts of honey and horse 70 parts of oil.
Further, include the raw material of following parts by weight proportioning：33 parts of macleaya cordata leaf, 28 parts of madder leaf, turmeric leaf 25 Part, 24 parts of littleflower plumbagella herb leaf, 8 parts of psoralea corylifolia fruit, 20 parts of teasel root, 9 parts of Armstrong, 22 parts of Rhizoma Atractylodis Macrocephalae, 3 parts of nano-calcium carbonate, sodium alginate 9 parts, 12 parts of frankincense, 7 parts of oleanolic acid, 4 parts of Essential Oil From Pine Needles, 4 parts of Pogostemon cablin essential, 7 parts of deodar essential oil, 35 parts of honey and horse 79 parts of oil.
Further, include the raw material of following parts by weight proportioning：30 parts of macleaya cordata leaf, 25 parts of madder leaf, turmeric leaf 23 Part, 21 parts of littleflower plumbagella herb leaf, 7 parts of psoralea corylifolia fruit, 19 parts of teasel root, 7 parts of Armstrong, 21 parts of Rhizoma Atractylodis Macrocephalae, 2 parts of nano-calcium carbonate, sodium alginate 8 parts, 11 parts of frankincense, 7 parts of oleanolic acid, 4 parts of Essential Oil From Pine Needles, 3 parts of Pogostemon cablin essential, 6 parts of deodar essential oil, 33 parts of honey and horse 75 parts of oil.
Another technical problem to be solved by the present invention is that a kind of preparation method of ointment that treating tinea of feet and hands is provided, including with Lower step：
1) by 28-33 parts of macleaya cordata leaf, 19-28 parts of madder leaf, 20-25 parts of turmeric leaf, 17-24 parts of littleflower plumbagella herb leaf and Psoralen 5-8 parts of fat fruit, which is poured into together in juice extractor, carries out squeezing processing, and juice and slag object is made, spare；
2) slag charge made from step 1) is poured into vessel, the moisture of Double Weight is then added, is boiled with high heat to boiling It rises, 20-22 parts of 17-20 parts of teasel root, 4-9 parts of Armstrong and Rhizoma Atractylodis Macrocephalae is then added and 2h is boiled with slow fire, filter off scaling-off object, after And 30-35 parts of honey is added, and it is boiled with slow fire, until to paste is become, ointment is made, it is spare；
3) juice made from step 1) is poured into progress low-temperature evaporation processing in low-temperature evaporation thickener, water content is steamed It is sent to 25-35wt%, concentrated juice is made, it is spare；
4) concentrated juice made from ointment made from step 2) and step 3) is poured into together in agitator tank, is then added 6-7 parts of 1-3 parts of nano-calcium carbonate, 7-9 parts of sodium alginate, 10-12 parts of frankincense and oleanolic acid carry out at heating stirring mixing Reason, wherein the mixing speed of heating stirring mixed processing is 85-150r/min, and heating temperature is 40-55 DEG C, and heating time is 20-40min, mixing time 1-2h place room temperature, and paste mixture is made, spare；
5) 3-4 parts of Essential Oil From Pine Needles, 1-4 parts of Pogostemon cablin essential, 5-7 parts of deodar essential oil, 70-79 parts of house oil and step 4) are made The paste mixture obtained is poured into agitator tank together is stirred mixed processing, wherein mixing time 40-60min, stirring Speed is 40-100r/min to get ointment.
The beneficial effects of the invention are as follows：By using macleaya cordata leaf, madder leaf, turmeric leaf, littleflower plumbagella herb leaf and psoralea corylifolia The effect cooperation Essential Oil From Pine Needles of the treatment dermatophytosis of the traditional Chinese medicine ingredients such as fruit, the sterilization effect of Pogostemon cablin essential and deodar essential oil Fruit can effectively treat dermatophytosis, while teasel root and madder leaf compounding can promote the fester of vesicle tinea of feet and hands to arrange Go out, while the effect cooperation frankincense and Pogostemon cablin essential of the promotion regeneration of teasel root, can effectively promote site of disease and restore speed Degree.
It is the drug effect of the Chinese medicine material for the ointment for treating tinea of feet and hands below：
Macleaya cordata leaf：Bitter, pungent, cold in nature, temperature cures mainly the scattered stasis of blood；Wind-dispelling；Removing toxic substances；Analgesic；Desinsection, pain sore malignant boil are swollen；Ulcer on the shank； Hemorrhoid；Eczema；Snakebite and bugbite；Treating swelling and pain by traumatic injury；Rheumatic arthritis；Caries pain；Stubborn dermatitis.
Madder leaf：It is cold in nature enter blood system, can cooling blood and hemostasis, and can stagnation resolvation.Cure mainly blood-head spitting of blood, haematemesis, bleeding from five sense organs or subcutaneous tissue, hematuria, just Blood, uterine bleeding, Amenorrhea, postpartum stasis abdominal pain, traumatic injury, arthralgia pain due to rheumatism, jaundice, sore carbuncle, hemorrhoid are swollen, have the function of apocenosis.
Turmeric leaf：Energy promoting the circulation of qi broken stasis of blood, it is inducing meastruation to relieve menalgia.Cure mainly chest and abdomen swelling and pain, shoulder arm numbness pain, it is pained unbearably, postpartum blood pain, sore Tinea is initial.With there is strength antifungic action.
Littleflower plumbagella herb leaf：It is fine to treat tinea effect.
Psoralea corylifolia fruit：Psoralea corylifolia fruit medicine, have tonifying kidney and strengthening yang, good efficacy to suffering from a deficiency of the kidney function, and the skins such as psoriasis can be controlled Disease.
Teasel root：The dry root of Dipsacaceae plant teasel.Its slightly warm in nature, it is bitter, pungent；Return liver and kidney channel.With analgesic, Myogenic meat goes all epidemic heat syndromes, and the effect of also apocenosis, promotion regeneration.
Armstrong：Desinsection is antipruritic to treat the parasitic diseases such as pinworm.It also can decoction washout treatment skin sore rash, itch.
Rhizoma Atractylodis Macrocephalae：There is inhibiting effect to acrothesium floccosum, star nocardia.
Sodium alginate：With stability, dissolubility, viscosity and the safety needed for pharmaceutical preparation auxiliary material.Utilizing seaweed When sour sodium is as thickener, addition nano-calcium carbonate can play the role of concertedness.The viscosity of sodium alginate can be greatly improved.
Nano-calcium carbonate：Nano-calcium carbonate is added in lotion can improve its extrusion performance.
Frankincense：Blood-activating and qi-promoting relieves pain, detumescence and promoting granulation.
Oleanolic acid：For broad spectrum antibiotic, have the function of promoting cytothesis.
Essential Oil From Pine Needles：Have the function of anti-inflammatory, antibacterial, it is valuable for the skin of obstruction, and eczema, chronic eczema also can be by Pine tree essence oil is improved.
Pogostemon cablin essential：Promoting skin regeneration, there is a good bactericidal effect, dephlogistication phenomenon restrains pore, Firm, Wound is promoted to scab, for preventing bacterium infection, treatment useless fellow, eczema and psoriasis etc..With oleanolic acid with can play The good effect for promoting cytothesis.
Deodar essential oil：There are significant antiinflammation, antibacterial, convergence, diuresis, softness, resolving sputum, killing fungus.It can help to eliminate Scab, purulence and some chronic diseases, such as eczema and chronic eczema.It is compounded with frankincense, there is the effect of apparent softening skin.It is effectively improved Suffer from the effect of the dry skin at tinea.
Honey：Have the function of nourishing, moisturize, detoxify, the dry skin suffered from tinea is effectively improved with deodar essential oil compounding Effect.
House oil：The nutrient (vitamin e and leukotrienes) contained in house oil can restore human body health and keep skin tender, and And immunity and resistance to disease can be reinforced.It uses and can drive the air in pore gap out of on the skin of human body, And subcutaneous tissue is infiltrated into, and it is absorbed simultaneously in nutrient, not but not cutaneous respiration is hindered, and skin health can be made, grown Moisten skin and promotes vis medicatrix naturae and metabolism.It is very helpful to tinea alba.
Specific implementation mode
Embodiment 1：
A kind of ointment for treating tinea of feet and hands includes the raw material of following parts by weight proportioning：28 parts of macleaya cordata leaf, madder leaf 19 Part, 20 parts of turmeric leaf, 17 parts of littleflower plumbagella herb leaf, 5 parts of psoralea corylifolia fruit, 17 parts of teasel root, 4 parts of Armstrong, 20 parts of Rhizoma Atractylodis Macrocephalae, nano-calcium carbonate 1 Part, 7 parts of sodium alginate, 10 parts of frankincense, 6 parts of oleanolic acid, 3 parts of Essential Oil From Pine Needles, 1 part of Pogostemon cablin essential, 5 parts of deodar essential oil, bee 70 parts of 30 parts of honey and house oil.
A kind of preparation method of ointment that treating tinea of feet and hands includes the following steps：
1) together by 5 parts of 28 parts of macleaya cordata leaf, 19 parts of madder leaf, 20 parts of turmeric leaf, 17 parts of littleflower plumbagella herb leaf and psoralea corylifolia fruit It is poured into juice extractor and carries out squeezing processing, juice and slag object is made, it is spare；
2) slag charge made from step 1) is poured into vessel, the moisture of Double Weight is then added, is boiled with high heat to boiling It rises, 20 parts of 17 parts of teasel root, 4 parts of Armstrong and Rhizoma Atractylodis Macrocephalae is then added and 2h is boiled with slow fire, filter off scaling-off object, honey is then added It 30 parts, is boiled with slow fire, until to paste is become, ointment is made, it is spare；
3) juice made from step 1) is poured into progress low-temperature evaporation processing in low-temperature evaporation thickener, water content is steamed It is sent to 25wt%, concentrated juice is made, it is spare；
4) concentrated juice made from ointment made from step 2) and step 3) is poured into together in agitator tank, is then added 6 parts of 1 part of nano-calcium carbonate, 7 parts of sodium alginate, 10 parts of frankincense and oleanolic acid progress heating stirring mixed processings, wherein heating The mixing speed for being stirred processing is 85r/min, and heating temperature is 40 DEG C, heating time 20min, mixing time 1h, Room temperature is placed, paste mixture is made, it is spare；
5) by paste made from 3 parts of Essential Oil From Pine Needles, 1 part of Pogostemon cablin essential, 5 parts of deodar essential oil, 70 parts of house oil and step 4) Mixture is poured into agitator tank is stirred mixed processing together, wherein mixing time 40min, mixing speed 40r/ Min is to get ointment.
Embodiment 2：
A kind of ointment for treating tinea of feet and hands includes the raw material of following parts by weight proportioning：33 parts of macleaya cordata leaf, madder leaf 28 Part, 25 parts of turmeric leaf, 24 parts of littleflower plumbagella herb leaf, 8 parts of psoralea corylifolia fruit, 20 parts of teasel root, 9 parts of Armstrong, 22 parts of Rhizoma Atractylodis Macrocephalae, nano-calcium carbonate 3 Part, 9 parts of sodium alginate, 12 parts of frankincense, 7 parts of oleanolic acid, 4 parts of Essential Oil From Pine Needles, 4 parts of Pogostemon cablin essential, 7 parts of deodar essential oil, bee 79 parts of 35 parts of honey and house oil.
A kind of preparation method of ointment that treating tinea of feet and hands, includes the following steps：
1) together by 8 parts of 33 parts of macleaya cordata leaf, 28 parts of madder leaf, 25 parts of turmeric leaf, 24 parts of littleflower plumbagella herb leaf and psoralea corylifolia fruit It is poured into juice extractor and carries out squeezing processing, juice and slag object is made, it is spare；
2) slag charge made from step 1) is poured into vessel, the moisture of Double Weight is then added, is boiled with high heat to boiling It rises, 22 parts of 20 parts of teasel root, 9 parts of Armstrong and Rhizoma Atractylodis Macrocephalae is then added and 2h is boiled with slow fire, filter off scaling-off object, honey is then added It 35 parts, is boiled with slow fire, until to paste is become, ointment is made, it is spare；
3) juice made from step 1) is poured into progress low-temperature evaporation processing in low-temperature evaporation thickener, water content is steamed It is sent to 35wt%, concentrated juice is made, it is spare；
4) concentrated juice made from ointment made from step 2) and step 3) is poured into together in agitator tank, is then added 7 parts of 3 parts of nano-calcium carbonate, 9 parts of sodium alginate, 12 parts of frankincense and oleanolic acid progress heating stirring mixed processings, wherein heating The mixing speed for being stirred processing is 150r/min, and heating temperature is 55 DEG C, heating time 40min, mixing time 2h, Room temperature is placed, paste mixture is made, it is spare；
5) by paste made from 4 parts of Essential Oil From Pine Needles, 4 parts of Pogostemon cablin essential, 7 parts of deodar essential oil, 79 parts of house oil and step 4) Mixture is poured into agitator tank is stirred mixed processing together, wherein mixing time 60min, mixing speed 100r/ Min is to get ointment.
Embodiment 3：
A kind of ointment for treating tinea of feet and hands includes the raw material of following parts by weight proportioning：30 parts of macleaya cordata leaf, madder leaf 25 Part, 23 parts of turmeric leaf, 21 parts of littleflower plumbagella herb leaf, 7 parts of psoralea corylifolia fruit, 19 parts of teasel root, 7 parts of Armstrong, 21 parts of Rhizoma Atractylodis Macrocephalae, nano-calcium carbonate 2 Part, 8 parts of sodium alginate, 11 parts of frankincense, 7 parts of oleanolic acid, 4 parts of Essential Oil From Pine Needles, 3 parts of Pogostemon cablin essential, 6 parts of deodar essential oil, bee 75 parts of 33 parts of honey and house oil.
A kind of preparation method of ointment that treating tinea of feet and hands, includes the following steps：
1) together by 7 parts of 30 parts of macleaya cordata leaf, 25 parts of madder leaf, 23 parts of turmeric leaf, 21 parts of littleflower plumbagella herb leaf and psoralea corylifolia fruit It is poured into juice extractor and carries out squeezing processing, juice and slag object is made, it is spare；
2) slag charge made from step 1) is poured into vessel, the moisture of Double Weight is then added, is boiled with high heat to boiling It rises, 21 parts of 19 parts of teasel root, 7 parts of Armstrong and Rhizoma Atractylodis Macrocephalae is then added and 2h is boiled with slow fire, filter off scaling-off object, honey is then added It 33 parts, is boiled with slow fire, until to paste is become, ointment is made, it is spare；
3) juice made from step 1) is poured into progress low-temperature evaporation processing in low-temperature evaporation thickener, water content is steamed It is sent to 30wt%, concentrated juice is made, it is spare；
4) concentrated juice made from ointment made from step 2) and step 3) is poured into together in agitator tank, is then added 7 parts of 2 parts of nano-calcium carbonate, 8 parts of sodium alginate, 11 parts of frankincense and oleanolic acid progress heating stirring mixed processings, wherein heating The mixing speed for being stirred processing is 100r/min, and heating temperature is 50 DEG C, heating time 30min, mixing time 2h, Room temperature is placed, paste mixture is made, it is spare；
5) by paste made from 4 parts of Essential Oil From Pine Needles, 3 parts of Pogostemon cablin essential, 6 parts of deodar essential oil, 75 parts of house oil and step 4) Mixture is poured into agitator tank is stirred mixed processing together, wherein mixing time 50min, mixing speed 70r/ Min is to get ointment.
Experimental example：
Experimental subjects：120 triers, randomized are divided into 4 groups：Experimental group one, experimental group two, experimental group three and control Group, every group of 30 people.
Test method：Experimental group one uses ointment made from embodiment 2 using ointment made from embodiment 1, experimental group two, Experimental group three uses the ointment for the treatment of dermatophytosis on the market, usage time using ointment made from embodiment 3, control group It it is 3 days, dosage is every 5 square millimeters and uses 0.1-0.15g.
4 groups of 3 days effects of user compare, and as a result see the table below：
By checking 4 groups of experiments, the use of experimental group one, experimental group two and experimental group three compared to control group is imitated Fruit will get well.
The beneficial effects of the invention are as follows：By using macleaya cordata leaf, madder leaf, turmeric leaf, littleflower plumbagella herb leaf and psoralea corylifolia The effect cooperation Essential Oil From Pine Needles of the treatment dermatophytosis of the traditional Chinese medicine ingredients such as fruit, the sterilization effect of Pogostemon cablin essential and deodar essential oil Fruit can effectively treat dermatophytosis, while teasel root and madder leaf compounding can promote the fester of vesicle tinea of feet and hands to arrange Go out, while the effect cooperation frankincense and Pogostemon cablin essential of the promotion regeneration of teasel root, can effectively promote site of disease and restore speed Degree.
The above description is merely a specific embodiment, but scope of protection of the present invention is not limited thereto, any The change or replacement expected without creative work should all be covered within the scope of the present invention.

Claims (5)

1. a kind of ointment for treating tinea of feet and hands, which is characterized in that include the raw material of following parts by weight proportioning：Macleaya cordata leaf 28- 33 parts, it is 19-28 parts of madder leaf, 20-25 parts of turmeric leaf, 17-24 parts of littleflower plumbagella herb leaf, 5-8 parts of psoralea corylifolia fruit, 17-20 parts of teasel root, flat Store 4-9 parts, 20-22 parts of Rhizoma Atractylodis Macrocephalae, 1-3 parts of nano-calcium carbonate, 7-9 parts of sodium alginate, 10-12 parts of frankincense, 6-7 parts of oleanolic acid, 70-79 parts of 3-4 parts of Essential Oil From Pine Needles, 1-4 parts of Pogostemon cablin essential, 5-7 parts of deodar essential oil, 30-35 parts of honey and house oil.
2. a kind of ointment for treating tinea of feet and hands as described in claim 1, which is characterized in that including following parts by weight proportioning Raw material：It is 28 parts of macleaya cordata leaf, 19 parts of madder leaf, 20 parts of turmeric leaf, 17 parts of littleflower plumbagella herb leaf, 5 parts of psoralea corylifolia fruit, 17 parts of teasel root, flat Store 4 parts, it is 20 parts of Rhizoma Atractylodis Macrocephalae, 1 part of nano-calcium carbonate, 7 parts of sodium alginate, 10 parts of frankincense, 6 parts of oleanolic acid, 3 parts of Essential Oil From Pine Needles, wide 70 parts of 1 part of Agastache rugosa, 5 parts of deodar essential oil, 30 parts of honey and house oil.
3. a kind of ointment for treating tinea of feet and hands as described in claim 1, which is characterized in that including following parts by weight proportioning Raw material：It is 33 parts of macleaya cordata leaf, 28 parts of madder leaf, 25 parts of turmeric leaf, 24 parts of littleflower plumbagella herb leaf, 8 parts of psoralea corylifolia fruit, 20 parts of teasel root, flat Store 9 parts, it is 22 parts of Rhizoma Atractylodis Macrocephalae, 3 parts of nano-calcium carbonate, 9 parts of sodium alginate, 12 parts of frankincense, 7 parts of oleanolic acid, 4 parts of Essential Oil From Pine Needles, wide 79 parts of 4 parts of Agastache rugosa, 7 parts of deodar essential oil, 35 parts of honey and house oil.
4. a kind of ointment for treating tinea of feet and hands as described in claim 1, which is characterized in that including following parts by weight proportioning Raw material：It is 30 parts of macleaya cordata leaf, 25 parts of madder leaf, 23 parts of turmeric leaf, 21 parts of littleflower plumbagella herb leaf, 7 parts of psoralea corylifolia fruit, 19 parts of teasel root, flat Store 7 parts, it is 21 parts of Rhizoma Atractylodis Macrocephalae, 2 parts of nano-calcium carbonate, 8 parts of sodium alginate, 11 parts of frankincense, 7 parts of oleanolic acid, 4 parts of Essential Oil From Pine Needles, wide 75 parts of 3 parts of Agastache rugosa, 6 parts of deodar essential oil, 33 parts of honey and house oil.
5. a kind of preparation method of ointment that treating tinea of feet and hands, which is characterized in that include the following steps：
1）By 28-33 parts of macleaya cordata leaf, 19-28 parts of madder leaf, 20-25 parts of turmeric leaf, 17-24 parts of littleflower plumbagella herb leaf and psoralea corylifolia fruit 5-8 parts are poured into juice extractor and carry out squeezing processing together, and juice and slag object is made, spare；
2）By step 1）Slag charge obtained is poured into vessel, and the moisture of Double Weight is then added, boils with high heat to boiling, so 20-22 parts of 17-20 parts of teasel root, 4-9 parts of Armstrong and Rhizoma Atractylodis Macrocephalae are added afterwards and 2h is boiled with slow fire, filters off scaling-off object, is then added 30-35 parts of honey, is boiled with slow fire, until to paste is become, ointment is made, spare；
3）By step 1）Juice obtained is poured into progress low-temperature evaporation processing in low-temperature evaporation thickener, and water content is evaporated to Concentrated juice is made in 25-35wt%, spare；
4）By step 2）Ointment obtained and step 3）Concentrated juice obtained is poured into agitator tank together, and nanometer is then added 6-7 parts of 1-3 parts of calcium carbonate, 7-9 parts of sodium alginate, 10-12 parts of frankincense and oleanolic acid progress heating stirring mixed processings, In, the mixing speed of heating stirring mixed processing is 85-150r/min, and heating temperature is 40-55 DEG C, heating time 20- 40min, mixing time 1-2h place room temperature, and paste mixture is made, spare；
5）By 3-4 parts of Essential Oil From Pine Needles, 1-4 parts of Pogostemon cablin essential, 5-7 parts of deodar essential oil, 70-79 parts of house oil and step 4）It is obtained Paste mixture is poured into agitator tank is stirred mixed processing together, wherein mixing time 40-60min, mixing speed It is 40-100r/min to get ointment.
CN201810369240.7A 2018-04-23 2018-04-23 A kind of ointment and preparation method thereof for treating tinea of feet and hands Pending CN108392598A (en)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101559136A (en) * 2008-04-18 2009-10-21 唐则荣 Combined medicament for treating tinea corporis and tinea manus and pedis and preparation method thereof
CN103055222A (en) * 2012-12-03 2013-04-24 展继军 Medicine for treating tinea manus and pedis
CN104027692A (en) * 2014-05-15 2014-09-10 陈松 Traditional Chinese medicine preparation for treating beriberi

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101559136A (en) * 2008-04-18 2009-10-21 唐则荣 Combined medicament for treating tinea corporis and tinea manus and pedis and preparation method thereof
CN103055222A (en) * 2012-12-03 2013-04-24 展继军 Medicine for treating tinea manus and pedis
CN104027692A (en) * 2014-05-15 2014-09-10 陈松 Traditional Chinese medicine preparation for treating beriberi

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