CN108380159A - A kind of full tumour antigen preparation facilities of glioma - Google Patents

A kind of full tumour antigen preparation facilities of glioma Download PDF

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Publication number
CN108380159A
CN108380159A CN201810265634.8A CN201810265634A CN108380159A CN 108380159 A CN108380159 A CN 108380159A CN 201810265634 A CN201810265634 A CN 201810265634A CN 108380159 A CN108380159 A CN 108380159A
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CN
China
Prior art keywords
tracheae
agitator
cover board
shaft
glioma
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201810265634.8A
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Chinese (zh)
Inventor
李欣
于佳楠
孙红梅
迟男男
李丛言
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Jiamusi University
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Jiamusi University
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Publication date
Application filed by Jiamusi University filed Critical Jiamusi University
Priority to CN201810265634.8A priority Critical patent/CN108380159A/en
Publication of CN108380159A publication Critical patent/CN108380159A/en
Pending legal-status Critical Current

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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/18Stationary reactors having moving elements inside
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0011Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
    • A61L2/0029Radiation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2202/00Aspects relating to methods or apparatus for disinfecting or sterilising materials or objects
    • A61L2202/20Targets to be treated
    • A61L2202/21Pharmaceuticals, e.g. medicaments, artificial body parts

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

The invention discloses a kind of full tumour antigen preparation facilities of glioma, including shell, the inside of the shell is equipped with agitator and sterilamp, the sterilamp is equipped with multiple, the sterilamp is about agitator circumferentially array, geometrical clamp is installed on the inner wall of the agitator, the second tracheae is clamped on the geometrical clamp, second tracheae is equipped with more, the top of second tracheae is communicated with the first tracheae of annular, the side of second tracheae is communicated with nozzle, the bottom of the agitator is communicated with discharge nozzle, cover board is installed at the top of the agitator, motor is installed at the top of the cover board, the output shaft of the motor is downward through cover board and is connected with shaft, the side of the shaft is welded with stirring blade, it is plugged with feed pipe at the top of the cover board, the side of the shell is equipped with nitrogen gas tank.This invention ensures that the progress of reaction efficient stable, easy to operate, structure novel have good practicability.

Description

A kind of full tumour antigen preparation facilities of glioma
Technical field
The present invention relates to glioma technical fields more particularly to a kind of full tumour antigen of glioma to prepare dress It sets.
Background technology
Glioma is derived from neurepithelial tumour, is the most common malignant tumour of encephalic, accounts for about whole encephalics The 40-50% of tumour, it is high with incidence height, high recurrence rate, lethality, become the problem of oncotherapy.Traditional therapy master If performing the operation the survival probability of patient is improved with chemicotherapy.But the glioma positioned at critical function area is difficult to accomplish to cut entirely It removes.Radiotherapy is almost the conventional therapy of various glioma, but therapeutic evaluation differs, except medulloblastoma is quick to radiotherapy height Feel, outside ependymoma medium sensitivity, other types are insensitive to radiotherapy.Chemotherapeutics is limited to blood-brain barrier and the poison of drug is secondary Effect, curative effect are not affirmed still.In recent years, immunization therapy becomes effective treatment means of the glioma after operation, chemicotherapy.With Other modes use in conjunction specifically has very strong complementation, and the immune system that patient is damaged can be played recovery and be rebuild Unique curative effect, to further prevent the recurrence and transfer of tumour.
That there are reaction rates is slow in reaction for the existing device for preparing the full tumour antigen of glioma, and stirring is insufficient The problem of, lead to the efficiency for affecting preparation, sometimes even results in the incomplete phenomenon of reaction.
Invention content
The purpose of the present invention is to solve disadvantages existing in the prior art, and a kind of glioma proposed swells entirely Tumor antigen preparation facilities.
To achieve the goals above, present invention employs following technical solutions:
A kind of full tumour antigen preparation facilities of glioma, including shell, the inside of the shell are equipped with agitator And sterilamp, the sterilamp are equipped with multiple, the sterilamp is about agitator circumferentially array, on the inner wall of the agitator Geometrical clamp is installed, the second tracheae is clamped on the geometrical clamp, second tracheae is equipped with more, the top of second tracheae End is communicated with the first tracheae of annular, and the side of second tracheae is communicated with nozzle, and the bottom of the agitator is communicated with out Expects pipe is equipped with cover board at the top of the agitator, motor is equipped at the top of the cover board, the output shaft of the motor is downward Through cover board and it is connected with shaft, the side of the shaft is welded with stirring blade, and feed pipe is plugged at the top of the cover board, The side of the shell is equipped with nitrogen gas tank, and the gas outlet of the nitrogen gas tank is communicated with hose, is installed on the pipeline section of the hose There are pressure regulator valve and flow valve, the one end of the hose far from nitrogen gas tank to be connected to through cover board and with the first tracheae.
Preferably, the stirring blade is in cross.
Preferably, the first shut-off valve is installed on the pipeline section of the feed pipe, the second pipe is installed on the pipeline section of discharge nozzle Section valve.
Preferably, second tracheae is parallel with shaft.
Preferably, the output shaft of the motor is connect with shaft by shaft coupling.
Compared with prior art, the beneficial effects of the invention are as follows:
In the present invention by be arranged shell, stirring blade, shaft, discharge nozzle, nitrogen gas tank, pressure regulator valve, flow valve, hose, Cover board, motor, feed pipe, the first tracheae, the second tracheae, geometrical clamp, sterilamp, agitator and nozzle, it may be convenient to internally The fluid foods of portion's reaction are efficiently stirred, while being formed efficient mixed flow by high pressure draught and being moved, and influence will not be introduced The gas of reaction ensure that the progress of reaction efficient stable, easy to operate, structure novel have good practicability.
Description of the drawings
Fig. 1 is a kind of structural schematic diagram of the full tumour antigen preparation facilities of glioma proposed by the present invention;
Fig. 2 is a kind of the first tracheae and the second tracheae of the full tumour antigen preparation facilities of glioma proposed by the present invention Attachment structure schematic diagram.
In figure:1 shell, 2 stirring blades, 3 shafts, 4 discharge nozzles, 5 nitrogen gas tanks, 6 pressure regulator valves, 7 flow valves, 8 hoses, 9 lids Plate, 10 motors, 11 feed pipes, 12 first tracheaes, 13 second tracheaes, 14 geometrical clamps, 15 sterilamps, 16 agitators, 17 nozzles.
Specific implementation mode
Following will be combined with the drawings in the embodiments of the present invention, and technical solution in the embodiment of the present invention carries out clear, complete Site preparation describes, it is clear that described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.
Referring to Fig.1-2, the full tumour antigen preparation facilities of a kind of glioma, including shell 1, the inside installation of shell 1 There are an agitator 16 and sterilamp 15, sterilamp 15 is equipped with multiple, and sterilamp 15 is about the circumferentially array of agitator 16, agitator 16 Inner wall on geometrical clamp 14 is installed, be clamped with the second tracheae 13 on geometrical clamp 14, the second tracheae 13 is equipped with more, the second tracheae 13 top is communicated with the first tracheae 12 of annular, and the side of the second tracheae 13 is communicated with nozzle 17, and the bottom of agitator 16 connects It is connected with discharge nozzle 4, the top of agitator 16 is equipped with cover board 9, and the top of cover board 9 is equipped with motor 10, the output shaft of motor 10 Downward through cover board 9 and it is connected with shaft 3, the side of shaft 3 is welded with stirring blade 2, and the top of cover board 9 is plugged with feed pipe 11, the side of shell 1 is equipped with nitrogen gas tank 5, and the gas outlet of nitrogen gas tank 5 is communicated with hose 8, tune is equipped on the pipeline section of hose 8 Pressure valve 6 and flow valve 7, the one end of hose 8 far from nitrogen gas tank 5 are connected to through cover board 9 and with the first tracheae 12, and stirring blade 2 is in Cross is equipped with the first shut-off valve on the pipeline section of feed pipe 11, is equipped with the second pipeline section valve on the pipeline section of discharge nozzle 4, and second Tracheae 13 is parallel with shaft 3, and the output shaft of motor 10 is connect with shaft 3 by shaft coupling.
Operation principle:In use, the material for participating in reaction is passed by feed pipe 11 in agitator 16, start motor 10, motor 10 efficiently stirs reaction mass by shaft 3 and stirring blade 2, while nitrogen gas tank 5 passes through hose 8, One tracheae 12, the second tracheae 13 and nozzle 17 are passed through nitrogen into agitator 16, to pass through high pressure draught to internal material Blow and to form that more efficient mixed flow is dynamic, improves the efficiency of materials inside reaction, easy to operate, structure novel has very Good practicability.
The foregoing is only a preferred embodiment of the present invention, but scope of protection of the present invention is not limited thereto, Any one skilled in the art in the technical scope disclosed by the present invention, according to the technique and scheme of the present invention and its Inventive concept is subject to equivalent substitution or change, should be covered by the protection scope of the present invention.

Claims (5)

1. a kind of full tumour antigen preparation facilities of glioma, including shell (1), which is characterized in that the shell (1) it is interior Portion is equipped with agitator (16) and sterilamp (15), and the sterilamp (15) is equipped with multiple, and the sterilamp (15) is about stirring Bucket (16) circumferentially array is equipped with geometrical clamp (14) on the inner wall of the agitator (16), is clamped on the geometrical clamp (14) There is the second tracheae (13), second tracheae (13) is equipped with more, and the top of second tracheae (13) is communicated with the of annular The side of one tracheae (12), second tracheae (13) is communicated with nozzle (17), and the bottom of the agitator (16) is communicated with out Expects pipe (4) is equipped with cover board (9) at the top of the agitator (16), motor (10), institute is equipped at the top of the cover board (9) The output shaft of motor (10) is stated downward through cover board (9) and is connected with shaft (3), the side of the shaft (3) is welded with stirring Blade (2) is plugged with feed pipe (11) at the top of the cover board (9), and the side of the shell (1) is equipped with nitrogen gas tank (5), institute The gas outlet for stating nitrogen gas tank (5) is communicated with hose (8), and pressure regulator valve (6) and flow valve are equipped on the pipeline section of the hose (8) (7), the one end of the hose (8) far from nitrogen gas tank (5) is connected to through cover board (9) and with the first tracheae (12).
2. the full tumour antigen preparation facilities of a kind of glioma according to claim 1, which is characterized in that the stirring Blade (2) is in cross.
3. the full tumour antigen preparation facilities of a kind of glioma according to claim 1, which is characterized in that the charging It manages and the first shut-off valve is installed on the pipeline section of (11), the second pipeline section valve is installed on the pipeline section of discharge nozzle (4).
4. the full tumour antigen preparation facilities of a kind of glioma according to claim 1, which is characterized in that described second Tracheae (13) is parallel with shaft (3).
5. the full tumour antigen preparation facilities of a kind of glioma according to claim 1, which is characterized in that the motor (10) output shaft is connect with shaft (3) by shaft coupling.
CN201810265634.8A 2018-03-28 2018-03-28 A kind of full tumour antigen preparation facilities of glioma Pending CN108380159A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201810265634.8A CN108380159A (en) 2018-03-28 2018-03-28 A kind of full tumour antigen preparation facilities of glioma

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201810265634.8A CN108380159A (en) 2018-03-28 2018-03-28 A kind of full tumour antigen preparation facilities of glioma

Publications (1)

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CN108380159A true CN108380159A (en) 2018-08-10

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Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030161767A1 (en) * 2000-02-17 2003-08-28 Colin Ramshaw Rotating surface of revolution reactor with feed and collection mechanisms
CN103495373A (en) * 2013-10-17 2014-01-08 烟台新瑞环保科技有限公司 Novel gas distributor
CN204952890U (en) * 2015-08-24 2016-01-13 何纪江 Reaction kettle
CN205109646U (en) * 2015-11-24 2016-03-30 浙江大川新材料股份有限公司 Polyamine production polymerization cauldron agitating unit
CN206276299U (en) * 2016-12-14 2017-06-27 鄂文雯 A kind of practical food blending machine
CN107376810A (en) * 2017-08-24 2017-11-24 烟台宇诚企业管理咨询有限公司 A kind of highly effective and safe temperature and pressure control reactor

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030161767A1 (en) * 2000-02-17 2003-08-28 Colin Ramshaw Rotating surface of revolution reactor with feed and collection mechanisms
CN103495373A (en) * 2013-10-17 2014-01-08 烟台新瑞环保科技有限公司 Novel gas distributor
CN204952890U (en) * 2015-08-24 2016-01-13 何纪江 Reaction kettle
CN205109646U (en) * 2015-11-24 2016-03-30 浙江大川新材料股份有限公司 Polyamine production polymerization cauldron agitating unit
CN206276299U (en) * 2016-12-14 2017-06-27 鄂文雯 A kind of practical food blending machine
CN107376810A (en) * 2017-08-24 2017-11-24 烟台宇诚企业管理咨询有限公司 A kind of highly effective and safe temperature and pressure control reactor

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Application publication date: 20180810