CN108351920A - System and method for obtaining test result from body sample - Google Patents

System and method for obtaining test result from body sample Download PDF

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CN108351920A
CN108351920A CN201680045239.8A CN201680045239A CN108351920A CN 108351920 A CN108351920 A CN 108351920A CN 201680045239 A CN201680045239 A CN 201680045239A CN 108351920 A CN108351920 A CN 108351920A
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computing device
body sample
code
unique identification
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CN108351920B (en
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M.T.乔根森
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Biological Testing Co Ltd
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    • G16H10/00ICT specially adapted for the handling or processing of patient-related medical or healthcare data
    • G16H10/40ICT specially adapted for the handling or processing of patient-related medical or healthcare data for data related to laboratory analysis, e.g. patient specimen analysis
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
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    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B50/00ICT programming tools or database systems specially adapted for bioinformatics
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    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/20ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems

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Abstract

The present invention relates to the method and systems for obtaining test result from body sample in the case where being possible to keep anonymity during whole process.The system comprises:Container with unique identification code;Mobile/handheld computing device, including first identifier code reader, second identifier code reader and analysis component, the analysis component are configured as executing the one or more test to body sample.The container is suitable for preserving body sample.The mobile/handheld computing device is configured as the server from network site and/or fetches data from database, wherein the data packet includes body sample associated with unique identification code(It is one or more)Test result.

Description

System and method for obtaining test result from body sample
Technical field
The present invention relates to the system and method for obtaining test result from body sample.
Background technology
Based on age, gender, genetic background and life style, the general unsoundness of different phase of the people in its life is asked Topic and chronic disease.About individual human or animal physiology and/or medical condition knowledge to individual itself, pet owner and To he/her/its healthcare provider identifies problem before problem starts and prevents them is crucial.
Regular health checkup and test may assist in before problem starts and pinpoint the problems.However, only seldom people and Pet owner is inspected periodically together with his/her provider.This is carried due to several factors, such as health care Open hour, deciding ability, embarrassment and the consultant expenses of donor.
Especially when it includes the sexually transmitted disease of Chlamydia, gonorrhoea and bleb to be related to, people are not intended to these information As a part for their medical records.In addition, some and pet owner be not only to being related to his/her health care offer The physiological status of they or pet are monitored in the case of person(Such as analysis specific exercise and eating habit change it is whether effective) It is interested.
Accordingly, it is desired to provide a kind of for that need not inspected periodically together with his/her healthcare provider In the case of obtain about individuals or pet physiology and/or medical condition information method.
Meanwhile the run time equipped at laboratory optimization analytic unit is problematic, because they do not know daily How many sample reached.Accordingly, it would be desirable to be able to the system for solving both of these problems simultaneously.
Invention content
Present inventors have developed one kind in the case where being possible to keep anonymity during whole process from Body sample obtains the method and system of test result.Test to body sample be for individuals or pet physiology and/ Or the test of the biomarker of medical condition.
First aspect is related to a kind of method for obtaining test result from body sample, and the method includes following steps Suddenly:
The container for being suitable for preserving body sample is provided, the container includes unique identification code;
It is taken by the application executed on mobile/handheld computing device by calling the scanning function of mobile/handheld computing device Return the unique identification code, wherein the application executed on the mobile/handheld computing device is the unique identification code It is associated with multiple possible body sample tests;
It is selected from the multiple possible body sample test by the application executed on the mobile/handheld computing device One or more body sample tests;
One or more body samples are tested by mobile/handheld computing device handle is associated with the unique identification code The selection database that is transmitted to the server at network site and/or is transmitted at analytic unit;
Body sample is located in container;
By container transmission/transport analytic unit;
The container is received at the analytic unit;
By calling the scanning function of authentication code reader at the analytic unit unique mark is fetched from container Code;
Using the unique identification code pass is fetched from the server from network site and/or the database from analytic unit In the information that execute which body sample test to the body sample in container;
One or more body sample tests are executed to the body sample in container;
One or more body sample test results to the body sample in container are related to the unique identification code Connection, and be stored on the server at network site and/or on database;
Using described in being executed on the mobile/handheld computing device using the unique identification code from network position It the server at the place of setting and/or is fetched from database about one or more of body samples to the body sample in the container The information of this test result.
Term " body sample " include but is not limited to urine, saliva, breathing, hair, nail, Stomatocyte, oral fluid, Excrement, skin, sweat, nose liquid, mucus, sperm, vaginal fluid, blood, intraocular liquid, eye swab and earwax.
In one or more embodiments, body sample be selected from by urine, saliva, breathing, hair, nail, Stomatocyte, Oral fluid, excrement, skin, sweat, nose liquid, mucus, sperm, vaginal fluid, blood, intraocular liquid, eye swab and earwax composition Group.
In one or more embodiments, body sample is selected from the group being made of blood and urine.
In the present context, unique identification code is the generation for indicating to be suitable for preserving the unique mark of the container of body sample Code, such as ciphering sequence number(Such as electronic product code).Authentication code may include product(Container)Sequence number, is criticized model Number, build date, validity date, price, sell/sell country and mark product or with other relevant product identifications of product Relevant information.
Following form may be used in the code:One-dimensional bar code, two-dimensional bar, QR codes or one-dimensional bar code and/or The combination of two-dimensional bar and/or QR codes.
The code can also use RFID chip/label(Radio frequency identification)Form.
The code that can be read by electronic reader/scanner machine on mobile/handheld computing device by executing It is fetched using by calling the scanning function of mobile/handheld computing device.Therefore, the mobile/handheld computing device(Example Such as, smart phone)Including authentication code reader/scanner(For example, the camera of smart phone).
Unique identification code and multiple possible body samples are tested in the application executed on mobile/handheld computing device It is associated.Thus user can select multiple and different tests to his/her body sample.Testing the possibility of body sample is For the body biomarker of the physiology and/or medical condition of individuals or pet(Such as oxidative stress, antioxidant and inflammatory Biomarker)Test.
Although the usually main analysis executed using blood preparation to oxidative stress, antioxidant and inflammatory biomarker, But the present invention uses urine specimen, urine specimen with non-intruding mode and can be exposed to blood source by less skilled individual It is obtained in the case of the risk of pathogen is lower.In addition, the level of some biomarkers of blood sample may be due to haemolysis The release of red blood cell component or due to the precursor when blood is exposed to air in sample(Such as unsaturated lipids)In vitro oxygen Change and is substantially changed.
The test for multiple urine biologies label that urine executes is provided more steady than any individual urine biology label The strong assessment to individual health state.
In one or more embodiments, the user between the test of the possibility of the urine from urine specimen selects option It includes at least:It is directed to the test of at least one biomarker of inflammation, oxidative stress and antioxidant activity respectively.Test can be with In the liquid phase(In test tube or microplate hole)It executes, is suitable for the simple test paper method using dried reagent, or be merged into microfluid Or in current immunity detecting device.
Work as reactive oxygen species(ROS)(Such as lipid peroxide)Abnormal level when leading to molecular damage in body, meeting Oxidative stress occurs.ROS can be generated for example by fungi or viral infection, aging, UV radiation, pollution, excessive consumption of alcohol and smoking. ROS can further cause age-dependent macular degeneration and cataract.
Oxidative stress test may include merging specific malonaldehyde(MDA)Or 4- Hydroxynonenals(4HNE)Method is to quantify Lipid peroxidation, and/or merge Thiobarbituric Acid Reactive Substance(TBARS)Method to measure effect due to free radical and by It is oxidized to the wider range of the substance of aldehyde and ketone.These tests are known in the art and can be by analysis institutions appropriate To execute.Several other biomarkers can be used for the test for oxidative stress.The high-level indicating oxygen of these biomarkers Change stress individual in occur.The low-level of these biomarkers indicates healthy individuals.
Resistance to oxidation is tested(Sometimes referred to as oxidation resistance is tested)Using CUPRAC(The anti-oxidant energy of divalent copper reduction Power)Method measures multiple types by being present in urine specimen(Uric acid, protein, vitamin, dietary supplements)It is caused The summation of antioxidant activity.Alternatively or additionally, can come special measure or distinguish uric acid, anti-bad using modified method Blood protein or to other contributive substances of whole resistance to oxidation, to which monitoring is referred to as the substance of " anti-oxidant deposit ".This A little tests are well known in the art and can be executed by analysis institution appropriate.Other several biomarkers can be used for Test resistance to oxidation.The high value of resistance to oxidation(It is directed to a greater amount of biomarkers of resistance to oxidation)Indicate healthy individuals, Because the individual have can neutralize cause oxidative damage and stress free radical compound.
Inflammation is made of the physiology and pathology affair of a series of complex, which includes some protein(For example, such as The cell factor and COX-2 of IL-6 and IL-8 etc and the inducible form of nitricoxide synthase)Yield increase.By an oxygen Nitric oxide production can increase to up to 1000 times during inflammation caused by changing the induction isomers of nitrogen synthase, and It is proved to be the useful organisms label of inflammation.Urine nitric acid salt excretion increases in the patient with rheumatoid arthritis, and It is reduced in the patient for taking prednisolone.Because NO is relatively unstable, it is possible to by using its catabolite nitre of measurement Hydrochlorate and nitrite(Measure the summation of the nitrite or nitrite and nitrate in urine specimen(It is commonly abbreviated as NOx))Method test the yield of NO.These tests are well known in the art and can be by analysis machines appropriate Structure executes.In addition, although the protein of high level is related to nephrosis in urine, however, it is known that certain inflammatory cells because The effect of son, which makes to be detained by the hematoglobin protein that kidney is realized, to be reduced so that the raising of urine protein level associated with nephrosis The appropriateness horizontal compared to lower urine protein increases the biomarker that may be used as inflammation.Other several biomarkers can be used for For the detection of inflammation.The inflammation biomarker of higher level indicates to occur during inflammation is individual, may indicate that disease.It is relatively low Horizontal inflammation biomarker indicates healthy individuals.Chronic inflammation can cause Hay Fever, atherosclerosis and rheumatoid to close Section is scorching.Anti-inflammatory agent is also proved to significantly reduce heart disease, the incidence of diabetes, Alzheimer's disease and cancer.
It due to the sequencing to human genome, has become and is more and more obvious, although science of heredity is for sub-fraction Main function is played in the development of the disease of population, but science of heredity is only big to the general impacts of the main non-communicable diseases of the mankind About 15-20%.Particularly with highest morbidity and mortality in meter and developed country(Chronic disease, such as cancer, cardiovascular disease Disease, neurodegenerative disease and autoimmune disease)Disease development, it is important it is more be diet, life style(Including forging Refining, smoking, alcohol use)With the influence of environment.All of these factors taken together influence individual health and they cause inflammation and/or Oxidative stress increases or decreases.Moreover, oxidative stress may trigger some reactions for increasing level of inflammation.
Sexually transmitted disease can be directed to other tests of urine specimen, such as Chlamydia test, gonorrhoea test, mycoplasma are surveyed Examination, the test of urea substance, trichomonas vaginalis test, Gardnerella vaginalis test, the test of herpe simplex I/II types.
Almost all of biomarker(It is determined directly from test sample)It is preferred that by using advanced automation instrument Device most accurately, the biochemical measurement established recently measures.
Urine specimen can be handled optionally with substance, and the substance assists in keeping measured ingredient and storing or transporting Period is from decomposition, and/or prevents from generating additional reactive material in vitro, and/or prevents storing or transporting the phase in sample Between may change numerical value microorganism growth.
Some blood biomarkers of the oxidative stress status of instruction individual are briefly described below.Identical blood biology mark Note can be used for other instructions.
1. total olefine aldehydr.The test is measured to cytolipin plasma membrane and lipoprotein(That is LDL)Free radical attack lipid Peroxide(Malonaldehyde and 4- Hydroxynonenals)Product.In the measured value reflection body of the amount of serum lipid peroxide certainly The amount damaged by base.
2. aqueous hydroperoxides.The test measures aqueous hydroperoxides, and such as hydrogen peroxide can be with enzymatic oxidation Metal reaction has reactive hydroxyl to be formed very.The measured value of the amount of serum hydroperoxides reflects at that time in body The amount of the free radical of generation.
3. lipid hydroperoxide.It [is not hydrogen peroxide or lipid peroxide that the test, which measures lipid hydroperoxide, The product of damage, i.e. aldehyde(MDA)].The measured value of the amount of serum lipids hydroperoxides reflects oneself generated in body at that time By the amount of base.
4. automatic antibody oxidation-LDL.Angiocardiopathy development current and main theory be:LDL is aoxidized, coverlet Nucleus swallows, and monocyte becomes ' foam ' cell, then ' foam ' cell is stuck in arterial cell wall and causes fat Sour speckle lesion(Patch).The LDL of oxidation(Ox-LDL)Cause immune response to remove it from body.Immune response with it is whole The amount of Ox-LDL present in a body is directly proportional.Since most of Ox-LDL is in arterial cell wall, in serum It is not largely effective to measure Ox-LDL;Therefore, cardiovascular is presently considered to be to the autoimmune antibody measurement result of Ox-LDL The very strong risk indication amount of disease.
5. total iron.Unbonded iron can be by being catalyzed from hydrogen peroxide and strong reductant(Such as ascorbate or Homocysteine)Generation has reactive hydroxyl very much(Fenton's reaction)And play the role of prooxidant.High ferro(Excess load) It is associated with following items:A large amount of radical damage and the most of age-related diseases of development(Such as diabetes, heart disease and Cancer)High risk.
Iron binding capacity obtained by 6.(AIBC)It is not combine iron and therefore can receive(Capture)Free iron molecule Transferrins, ferritin and albumin amount.Known iron-binding protein matter is very well protected from iron catalysis free radical and generates. High AIBC provides the good initiation protected in order to avoid oxidative damage reacts.AIBC protein synthesizes in liver and in serum In be maintained at fairly constant steady-state level;In general, iron(The iron combined by protein)Higher, AIBC is lower.
7. total iron binding capacity(TIBC)It is indicated by value AIBC+ total iron.This value is used for reflecting that liver manufacture iron combines The ability of protein.
8. iron saturation degree percentage-is as a percentage(Total iron/TIBC).This is the opposite of iron and iron binding capacity Ratio;Iron saturation degree is higher, and the risk that iron participates in catalysis Kinds of Free Radicals is higher.
9. ferritin-is the iron-binding protein matter synthesized in response to the amount of Iron in Serum by liver.Ferritin is body Iron stores and the index of possible long-term iron overload.High ferritin levels are associated with following items in serum:Largely certainly Damaged by base and developed most of age-related diseases(Such as diabetes, heart disease and cancer)High risk.
10. bronze medal.Known unbonded copper even more has reactive prooxidant than iron, especially there is strong reduction Agent(Such as ascorbic acid(Vitamin C)Or homocysteine)In the case of.High copper level in serum can cause high level Oxidative damage and associated with high-caliber oxidative damage.CuZn-SOD and ceruloplasmin need few Amount.
11. up to the 95% of the copper found in ceruloplasmin combination serum.In normal patient, ceruloplasmin Amount it is directly proportional to the amount of Copper in Serum.Copper concentration is usually related to the risk of a large amount of lipid peroxidation and angiocardiopathy Connection.Ceruloplasmin is considered as antioxidant, therefore it serves as Ferroxidase(Aoxidize free iron), to inhibit its conduct Prooxidant participates in removing excessive iron from body, and is essential in removing excessive iron from body.Plasma copper Azurin also functions as superoxide dismutase.See that ceruloplasmin is reduced in Wilson's disease.
12. glucose.Glucose level instruction patient just in fasting or can indicate uncontrolled diabetes or low blood Sugared disease.
13. glycated proteins(Fructosamine)For being averaged during the last 1-3 weeks before measuring sample collection time Blood glucose level.The measurement measure serum in all glycated proteins [gross protein, including albumin, but include only exist in Hemoglobin in whole blood(RBC)].The amount of glycated proteins increases with oxidative stress and aging.
14. oxygen radical absorbability [ORAC] measures the total antioxidant capacity in sample.95% ORAC values indicate blood Snap action antioxidant in clear, snap action antioxidant constitute the first line of defence.These include ascorbic acid, mercaptan, Uric acid, bioflavonoid, polyphenol etc..50% ORAC values indicate the quick and intermediate effect antioxidant that serum uses, quickly Include the antioxidant of medium activity, such as albumin and lipid with intermediate effect antioxidant.
15. aqueous ORAC- measures the antioxidant after removing isolating protein and lipid in serum sample.Due to they Richness, almost half whole serum ORAC values come from protein and lipid.Most protein and lipid are not to have very much work The antioxidant of property(Victim), and reduce spirit of the ORAC measurement in terms of measuring less abundant but more active antioxidant Sensitivity.Lipid is removed from serum sample and protein increases spirit of the ORAC measurement in terms of measuring other water soluble antioxidants Sensitivity.
16. lipid ORAC- measures the antioxidant in serum sample after the protein of removal sample and water phase.Due to Their richness, more than half of whole serum ORAC values come from protein and aqueous antioxidant.It is removed from serum sample Protein and aqueous antioxidant increase sensitivity of the measurement to measurement fat-soluble antioxidant.
17. lipid peroxidation rejection ability [LPIC] measures.Plasma antioxidants can be classified as two kinds of main Types: (a)Main anti-oxidant, such as ceruloplasmin and transferrins, by reducing lipid peroxidation in conjunction with enzymatic oxidation metal Initiation rate;With(b)Auxiliary antioxidant, such as tocopherol reduce chain growth and the amplification of lipid peroxidation.Many antioxygens Agent(Such as uric acid)Also have a variety of oxidation resistance properties, these antioxidants can in conjunction with many enzymatic oxidation metals and directly Remove oxidative species.LPIC, which is measured, measures when main anti-oxidant and auxiliary antioxidant system work together in the sample him The two activity.In the mankind, low serum LPIC values have been demonstrated the development for indicating adult's onset diabetes strongly.
18. vitamin C [ascorbic acid].Ascorbic acid can directly remove oxidisability type, and can generate other The antioxidant aoxidized, such as vitamin E.However, there is the enzymatic oxidation metal that dissociates around(Iron, copper etc.)The case where Under, catalysis is generated oxidative free radical by ascorbic strong reducing power.
19. mercaptan is very active antioxidant and reducing agent.Most of serum thiols are then being swum in albumin From being found in cysteine and glutathione.Albumin mercaptan is considered serving as sacrificial antioxidant, almost without impaired The biological consequences of wound.Due to their high anti-oxidation reactivity and high concentration, albumin mercaptan serves as main shielding agent resistance pair The radical damage of cell membrane.
20. lutein is very active fat soluble carotenoids antioxidant(It is 2.3 times of vitamin E), hold Easily it is absorbed into serum.Lutein and zeaxanthin are the principal elements for preventing macular degeneration, and macular degeneration is the elderly's mistake The main reason for bright, and account for the 10% of all blindness numbers.
21. zeaxanthin is very active fat soluble carotenoids antioxidant(It is 2.8 times of vitamin E), It is easy to be absorbed into serum.Lutein and zeaxanthin are related with macular degeneration is prevented, and macular degeneration is the elderly's blindness Main cause, and account for the 10% of all blindness numbers.
22. beta-cryptoxanthin may be most active fat-soluble antioxidant(It is 3.1 times of vitamin E), it is easy quilt It is absorbed into serum.
23. lycopene is one of most active fat-soluble antioxidant(It is 2.8 times of vitamin E).Studies have shown that Lycopene may be extremely important in terms of preventing prostate cancer.
24. alpha-carotene is a kind of precursor of known antioxidant and vitamin A.Experimental evidence proves, α-carrot Element is antioxidant more stronger than beta carotene and cell differential agent and therefore can be more preferable in terms of pre- anti-cancer.
25. beta carotene is a kind of precursor of known antioxidant and vitamin A, diet benefit has been widely used as it Fill agent.It is strong cell differential agent, and therefore can pre- anti-cancer.
26. retinol [vitamin A] is a kind of known antioxidant and cell differential agent, and therefore can be given protection against cancer in advance Many aspects of disease and aging.
27. retinyl palmitate.The retinol ester in the source of vitamin A is most commonly used as in dietary supplements and food.
28. carotenoids.This group of carotenoid includes that very possible many beneficial to health is not true to type Carotenoid.This value provides the population value of good fruits and vegetables consumption figure.
29. alpha-tocopherol(Vitamin E)It is one of most typical and fat-soluble antioxidant of meal supplement.In addition to it is anti- Except oxidability, also there is cell differentiation attribute, cell differentiation attribute to be considered showing in terms of pre- anti-cancer good for it.
30. Delta-Tocopherol(Vitamin E).Although about Delta-Tocopherol to few known to the advantageous effect of the mankind, it It is generally found small amount in food and human serum.
31. Gamma-Tocopherol(Vitamin E).The main Types of the vitamin E found in heart, and therefore due to it It can be selected for body as antioxidant or as the particular feature of differentiation agent.
32. tocopherol/(Cholesterol+triglycerides).The ratio of lipid antioxidant and the amount of lipid to be protected. It was found that such parameter is provided than individually assessing these biomarkers for the much better of the risk for developing angiocardiopathy Instruction.
33. panthenol [ubiquinone IO] is synthesized usually as a part for Mitochondria system in cell, and It is present in lipid biomembrane.CoQIO can also be absorbed by diet, and can serve as very active antioxidant, and And protect LDL from oxidation.
34. cholesterol.Cholesterol is the well known painstaking effort realized by indicating the amount of the possible potential lipid aoxidized The risk of pipe disease indicates object.Angiocardiopathy development current theory be:LDL is aoxidized, and is swallowed by monocyte, and monokaryon is thin Born of the same parents become to be stuck in arterial cell wall and cause aliphatic acid speckle lesion(Patch)" foam " cell.
35. triglycerides.Triglycerides is the glycerine and Fatty acid compositions by being attached to the referred to as protein of lipoprotein Ester.Triglycerides and cholesterol all measure the total amount of lipoprotein in serum, which can be as the thick of risk of cardiovascular diseases Slightly index.The associated risk of cardiovascular diseases prediction provided by triglycerides and cholesterol itself is actually low (44%);But combined with vitamin A and E,(Cholesterol+triglycerides)/(Vitamin A and E)Ratio by risk profile energy Power is increased to 85% accuracy.
36. albumin.Each albumin molecule includes many very active thiol groups, and thiol group serves as effectively Antioxidant.Albumin is referred to as sacrificial antioxidant, because it does not have circulating path and the consequence of its damage is not straight Connect influence cell function.Albumin has high-conversion rate;Impaired albumin is degraded, and the amino that body has been reused Acid.Other most of Antioxidation Mechanisms use certain Direct Regeneration system(That is vitamin E, vitamin C and glutathione peroxidating Object enzyme).
Gross protein-includes albumin and immunoglobulin.Therefore, the amount of globulin can be according to simple in serum sample Equation calculate,
Globulin amount=gross protein-albumin amount.
38. albumins/globulins ratio is used as the generally labeling of health and kilter.Ideal ratio is 1.85 or more It is high.High immunoglobulinlg can indicate that Long-term Infection, Long-term Infection may increase the risk of development autoimmune disease.
39. homocysteine.Homocysteine is a kind of strong reductant, and can promote enzymatic oxidation metal catalytic Free radical generates.Homocysteine level increases highly relevant with the high risk of angiocardiopathy.It is high in Most patients Homocysteine is caused by folic acid and/or vitamin B12 deficiency.
40. folic acid.Folic acid participates in DNA synthesis, red blood cell regeneration and homocysteine metabolism.Low-level is lacked with birth It falls into, DNA damage and homocysteine accumulation are associated.Lacking leads to the raising of DNA mutation rate, LDL oxidations, irreversible neurodegeneration And anaemia.Folic acid and vitamin B12 are collaboration in terms of their effect.
41. vitamin B12 [cyanocobalamin].Vitamin B12 participates in DNA synthesis, red blood cell regeneration and homocysteine Metabolism.Low-level is associated with the accumulation of inborn defect, DNA damage and homocysteine.Lacking leads to the raising of DNA mutation rate, LDL Oxidation, irreversible neurodegeneration and anaemia.Vitamin B12 and folic acid are collaboration in terms of their effect.
42. low-density lipoprotein(LDL).It is known as ' bad ' cholesterol, LDL and heart disease risk positive in popular document It closes.By reducing free enzymatic oxidation metal, increase water soluble antioxidant(Albumin, uric acid and vitamin C)With it is fat-soluble Antioxidant(VitAVitE, CoQIO and carotenoid)It may be implemented to prevent LDL from being aoxidized.
43. high-density lipoprotein(HDL).It is known as ' good ' cholesterol, HDL and heart disease risk negative in popular document It closes.
44. apolipoprotein B is the protein mainly found on LDL, and is therefore actually the measurement of LDL.
45. aPoA is the protein mainly found on HDL, and is therefore actually the measurement of HDL.
46.5- dihydrotestosterones are known to cause male pattern alopecia and damage prostatic cell(This increases the wind of prostate cancer Danger)Testosterone toxic forms.
47. cortisol.Cortisol is a kind of steroid hormone, many different types of including oxidative stress It stress be raised period.Raised levels of cortisol is exposed to for a long time to have been demonstrated to accelerate the sign of aging.
48. dehydroepiandrosterone sulfate [DHEA-S].DHEA-S is referred to as main hormone, because it is swashed for many other The precursor of element synthesis.Since DHEA-S levels were shown with the age and reduce, thus it have recently become it is very popular Dietary supplements be used to hormonal readiness is increased to the range that the young stage of life sees.DHEA- sulfate is usually to deposit The form of storage in the body, and therefore compared with directly supplementing DHEA, which has less negative side-effects.
49. estradiol.Estradiol and the high risk of development breast cancer link together, especially in overdose replenishers In postmenopausal women.The estrogen of other forms is reported safer.The known higher women's ratio of long-term estradiol internal circulating load is just Normal women reaches climacteric earlier.
50. insulin-like growth factor-i [IGF-1].IGF-1 transmits human growth hormone(HGH)Effect, such as pierce Swash cell turnover, reparation and growth.In normal patient, IGF-1 is generated in liver, and the amount and growth hormone of generation are at just Than.Due to its long half time, IGF-1 can be used for measuring the average magnitude of the growth hormone discharged in 48 hours in the past.Because HGH exists There are many cycle peak values during entire day and night, so in terms of determining the insufficient or excessive releases of HGH, HGH's is single Serum determination is not very accurate.HGH and IGF-1, which is injected, has been demonstrated to help the elderly to rebuild muscle and strength, so as to improve Their quality of life.
51. progesterone.Progesterone is considered as the popular replenishers of enhancing memory and cognitive function at present.
52. testosterone.Testosterone is responsible for most of adult male characteristics(Such as facial hair and muscle growth)Expression and dimension It holds.However, testosterone may be in some cells(Such as hair follicle and prostatic cell)In be converted into toxic forms(Dihydrotestosterone, DHT), The toxic forms have damage to these cell types.
53. thyrotropic hormone(TSH).TSH stimulates thyroid cell to absorb iodine.
54. thyroxine(T4).Thyroxine is a kind of universal steroid hormone, adjusts metabolic rate and indicates suitable When thyroid function.The hydrogen peroxide as by-product is generated from iodine synthetic thyroid element.Those are high by thyroid function Into individual have shown that accelerate aging sign.
55. aluminium.The accumulation of aluminium is associated with by force with the morbidity of Alzheimer's disease in brain.This is considered as the effect of disease, Rather than reason.
56. antimony.Antimony is a kind of toxin, and without known human needs.
57. arsenic.Arsenic is a kind of well known poison for inhibiting breathing.
58. cadmium.Cadmium is a kind of well known toxin, is similar to mercury, and without known human needs.
59. calcium.Calcium helps Apoptosis, blood clotting and nerve signal transmission.Known low serum amount causes osteoporosis Disease, the growth of bone and tooth and maintenance are bad.
60 chromium.Industrial chrome is very toxic prooxidant.A small amount of Cr+3For adjusting blood glucose level function and sugar it is resistance to It is required in amount protein.
61. cobalt.Cobalt is the ingredient of vitamin B12.It may be toxic when being in high level.
62. bronze medal.Known unbonded copper is that even more have reactive prooxidant than iron, especially there is strong reduction Agent(Such as ascorbic acid or homocysteine)In the case of.The high level of copper can cause oxidative damage.CuZn- superoxides discriminations Change enzyme and ceruloplasmin needs on a small quantity.
63. iodine.Iodine is that synthetic thyroid hormone thyroxine is required, and the hydrogen peroxide that is synthetically produced is as by-product Object.Iodine is halogen(Such as fluorine and chlorine), and radical-forming agent can be readily served as.A large amount of iodine may be very toxic.
64. iron.Unbonded iron can be by being catalyzed from hydrogen peroxide and strong reductant(Such as ascorbic acid and high half Guang ammonia Acid)Generation has reactive hydroxyl and serves as prooxidant very much.High ferro(Excess load)It is associated with following items:Largely certainly Damaged by base and developed most of age-related diseases(Such as diabetes, heart disease and cancer)High risk.
65. lead.Lead is a kind of well known neurotoxin, does not have known human needs.
66. magnesium.Magnesium synthesizes RNA/DNA, protein synthesis, ADP is synthesized and contraction of muscle is necessary.Due to its tool There is+2 fixation exoelectron chemical valence, so it can inhibit many iron-baseds free by the way that iron is shifted from its binding site Base reaction of formation.Magnesium has been demonstrated to help to prevent heart disease.
67. manganese.Known unbonded manganese is strong prooxidant, especially there are strong reductants(Such as ascorbic acid or height Cysteine)In the case of.It is in toxic when high level.Manganese superoxide dismutase needs a small amount of.
68. mercury.Mercury is a kind of well known neurotoxin, does not have known human needs.
69. molybdenum.Molybdenum is converted in uric acid xanthine required for xanthine oxidase.Also in aldehyde oxidase and sulfurous In hydrochlorate oxidizing ferment molybdenum is needed in these toxic compounds being oxidized to the lower product of reactivity.Oxidizing ferment generates peroxidating By-product of the hydrogen as its reaction.
70 nickel.Known unbonded nickel is strong prooxidant and is in toxic when high level.Red blood cell and liver function It needs a small amount of.
71. selenium.Known unbonded selenium is the prooxidant for having similar chemical valence with oxygen.It is toxic in high level. Glutathione peroxidase needs a small amount of.
72 sulphur.Sulphur is essential for protein structure and enzymatic activity;It is also required to sulphur in the reaction of many toxin expellings, and And sulphur can reduce the risk of people's developing cancer.
73. strontium.Known strontium inhibits vitamin d synthesis;Therefore it may be osteoporosis and bone in the children developed One important risk factor of deformity.
74. tin.Tin is that appropriate metabolism and the growth of bone and tooth are required.
75. vanadium.Vanadium participates in lipid-metabolism.Lack vanadium to have been demonstrated to increase cholesterol levels(High dose does not drop cholesterol It is low to cross its normal set point).Ability of the current research assessment vanadium in terms of killing cancer cell.Vanadium may when being in high level It is toxic.
76. zinc.Zinc is necessary to metabolism, RNA polymerase and CuZn superoxide dismutases.Because it consolidates with+2 Exoelectron chemical valence is determined, so it can inhibit many iron-based radical reactions by the way that iron is shifted from its binding site. Zinc may be toxic when being in high level.
Almost all of biomarker(They are directly determined from test sample)It is preferred that by establishing most accurately, recently Biochemical measurement is measured using complicated, self-reacting device.
After selecting multiple body sample tests from the test of possible body sample, user is calculated by mobile/handheld Device is transmitted to the selection to the test of one or more body samples associated with unique identification code in network The server of position and/or the database being transmitted at analytic unit.
The data sent by mobile/handheld computing device may include authentication information, which identifies specific user And/or the mobile/handheld computing device of pet/animal and user.The authentication information may include user credential, such as with Name in an account book, password, e-mail address and the answer to safety issue, data access authority/limitation, mobile/handheld calculate dress The geographical location set and the information for uniquely identifying mobile/handheld computing device such as telephone number or are given birth to by user profiles At hash.
It may require user's service of logging on to of mobile/handheld computing device before any information is provided, and can be with Provide a user the explanation how and why their data are currently being used.It is also possible to provide a user following chance: Temporarily or permanently stop participating at any time.By requiring user to select to be added and logging in the service, this can also reduce examination Figure sends the third-party quantity of spam to the system.
Preferably, mobile/handheld computing device is smart phone or tablet computer.In such embodiments, uniquely The machine-readable representation of authentication code uses quick response(QR)Code or other matrixes(Two dimension)The form of bar code, this is other Matrix(Two dimension)Bar code can be by scanner(Such as by be programmed to identification and processing array bar code mobile phone or other The camera of mobile computing device)It reads.In alternative embodiments, the machine-readable representation use of coding information can be by mobile electricity Talk about or be programmed to the radio frequency identification that the radio frequency interface for the other mobile computing devices for identifying and handling RFID is read(RFID)'s Form.
Body sample can be by being used for body sample(Such as urine and blood)The device that is sampled obtains, and can be with It is positioned in the container for preserving body sample.In one or more embodiments, the container is configured to body Sample is sampled.
Second aspect is related to a kind of system for obtaining test result from body sample, including:
Container is suitable for preserving body sample, and the container includes unique identification code;
Mobile/handheld computing device, including first identifier code reader;
Second identifier code reader;With
Component is analyzed, is configured as executing the one or more test to body sample;
Wherein, the mobile/handheld computing device is configured as the server from network site and/or fetches number from database According to the data include body sample associated with unique identification code(It is one or more)Test result.
In one or more embodiments, mobile/handheld computing device is configured as selectively fetching and unique mark The associated data of code, the unique identification code had previously utilized the first identifier of the mobile/handheld computing device Code reader identifies.
In one or more embodiments, mobile/handheld computing device is configured to respond to user's input(Such as property Not, age, weight etc.)And recommend one or more body sample tests from multiple possible body sample tests.
In one or more embodiments, mobile/handheld computing device is configured to respond to form from by following items Group selection user input:Chronic conditions, family's genetic disease, age, nationality, ethnicity, gender, height, weight, body Body mass index(BMI), body volume index(BVI), genotype, phenotype, disease, disease severity, progression of disease rate, Measurement, quality of life, intervention and the remedial measure of Functional Capability, and recommend one from the multiple possible body sample test Or multiple body sample tests.
In one or more embodiments, mobile/handheld computing device is configured as one or more body samples to survey The selection of user's selection of examination sends the database at server and/or analytic unit at network site, user's choosing to Select selection with from suitable for preservation the unique identification code of container of body sample it is associated.
The analysis component can be any kind of component that test can be executed to body sample, as experimenter Auxiliary or as fully automatic system.
In one or more embodiments, the analysis component is configured as test result and body from body sample Body sample, which is stored in the unique identification code on container therein, to be associated, and stores it in the clothes at network site It is engaged on device and/or stores on the database.Alternatively, experimenter will protect the test result of body sample and body sample It is associated to be stored in the unique identification code on container therein, and store it on the server at network site and/ Or storage is on the database.
Second identifier code reader is used to the test result from body sample being stored in wherein with body sample Container on the unique identification code it is associated during.In certain embodiments, it can be the whole of analysis component Close part.
Container suitable for preserving body sample can have any suitable shape or size, and can be by being suitable for depositing Any material of storage body sample is made.Preferably, the material that container is transported by that can bear mail service(Such as rigid polymeric Object material)It is made.Preferably, the container is suitable for preserving the small size for medicine test(1-50ml)Body sample.It needs It is well known to want the medicine of such as urine and blood of small size to test.
In one or more embodiments, the container further includes for the device from skin sampling blood.In some realities It applies in example, for being the integrated part of container from the device of skin sampling blood.
In one or more embodiments, for including from the device of skin sampling blood:
(a)Fluid conducts plate unit, has an one or more openings for the skin for leaning against patient, and one or more lancets can be with Across the opening to puncture skin to lead to puncture wound, the plate unit has comes from puncture wound respectively for conduction Fluid channel;With
(b)One or more lancets are located in plate unit associated there nearby for being opened across one or more of Mouthful to puncture skin when being pressed into skin;
The wherein described plate unit includes the first passage for the first part of fluid to be conducted away and for conducting fluid The second channel of two parts.
Merging fluid conduction unit and in the case of lancet, only by by the unit put on the skin with push by Button, blood can be sampled easily, and be transferred to desired position.In a preferred embodiment, by using two or more Multiple channels, one of channel conductance are walked to include the fluid of the more initial fluid from puncture wound, more be represented intravascular The blood sample of blood can be delivered to storage location.In addition, the puncture dress of this ability with selection suitable blood part Compact, convenient plate-shaped unit can be manufactured by setting, it can be easily inserted into container.In addition, multiple lancings Needle can be disposed such that the distance between at least two lancets are in a limitation so that when actually more than one thorn Patient only perceives single puncture when blood pin puncture skin.
Human blood may need the quick separating of cellular blood component, to obtain serum or blood plasma, and therefore avoid sample This degradation.Dry blood filter solves the problems, such as this.
In one or more embodiments, container further includes dry blood filter.
In one or more embodiments, dry blood filter includes by antioxidant, coagulant, disinfectant, detergent At least one of the group formed with inhibitor substance.Hinder to these substance advantageous the degradation or change of sample.In addition, addition Disinfectant allows the dry blood speckles that the material spot originating from latent infection is transported by surface mail service to filter paper.It is this Disinfectant may include but be not limited to:Phenol and its derivatives, such as thymol, adjacent polyphenol;Cationic compound, as benzene pricks chlorine Ammonium, Chlorhexidine;Aldehyde, as formaldehyde or other;And alcohol, such as normal propyl alcohol.
Desired haemocyte and blood separation to avoid intracellular compound from cracking or be damaged and not completely Under the cell release conditions of haemolysis, filter according to the present invention includes that there is the micropore of unequal pore size to be used for from blood Starch washed corpuscles.Due to its larger diameter, haemocyte shows different permeability compared with blood plasma.
Simple solution for this problem is to use different types of filter paper and film, the filter paper and the impermeable blood of film Cell is to cause the separation of the cell and blood plasma by chromatography, filtering or capillary force.For example, being in dry blood filtration The permeable haemocyte of filter spot at device center and the impermeable haemocyte of surrounding paper.
Permitted with globulicidal material impregnation filter paper and other use without cracking using quick solidification/condensation is caused Perhaps the simple color indicator for identifying the filter paper region on the outside of blood clotting later, only has acellular blood in the filter paper region Liquid(Plasma/serum)" diffusion ".In this way, the filter paper region only impregnated by cell-free plasma can easily produce and know Not.
In one or more embodiments, the container is configured for from skin sampling blood.
In one or more embodiments, the container includes base portion and lid, the lid engage the base portion and with it is described Base portion coordinates to limit shell, and the shell is configured in the state of closing or opening;
Wherein, the lid includes the first and second usually opposite surface sides, and the wherein described second surface side is in closed form Towards the base portion in state.
In one or more embodiments, unique identification code is positioned in the second surface side of the lid and/or in base The surface side of the direction shell in portion.This is in order to when container has been loaded body sample and is therefore in closed state Hide the unique identification code.
In one or more embodiments, container further comprises tampered display lock(tamper evident lock).
In one or more embodiments, container further comprises that tampered display lock, tampered display lock include:
Lock body accommodates key lock, and the key lock includes keyhole;
Component on lock body, for permanent retention for preventing from accessing the effective sealing element of the keyhole;With
Only can be by being destroyed the sealing element to be removed from the holding member, the destruction of the sealing element is for display It is tampered effective.
In one or more embodiments, container further includes wanting the body sample in physical access container that must destroy(Example Such as removal is bent or fractures)Sealing element.
The third aspect is related to a kind of mobile/handheld computing device, including first identifier code reader;
Wherein, the mobile/handheld computing device is configured as the server from network site and/or fetches number from database According to the data include body sample associated with unique identification code(It is one or more)Test result.
In one or more embodiments, mobile/handheld computing device is configured as selectively fetching and unique mark The associated data of code, the unique identification code had previously utilized the first identifier of the mobile/handheld computing device Code reader is identified.
In one or more embodiments, mobile/handheld computing device be configured to the unique identification code with it is more A possible body sample test is associated.
Fourth aspect is related to a kind of container being suitable for preserving body sample, and the container includes base portion and lid, and the lid connects It closes the base portion and coordinates to limit shell with the base portion, the shell is configured in the state of closing or opening;
Wherein, the lid includes the first and second usually opposite surface sides, and the wherein described second surface side is in closed form Towards the base portion in state;
The wherein described unique identification code be positioned in the second surface side of the lid and/or be located in base portion towards shell Surface side.
It should be pointed out that the embodiment and feature described in context in one aspect of the invention are also applied for this Other aspects of invention.
Description of the drawings
Fig. 1 shows system according to various embodiments of the present invention;
Fig. 2A-B show container according to various embodiments of the present invention;And
Fig. 3 shows the exemplary implementation of the user interface of the mobile computing device for using in the system and method for the present invention Example.
Specific implementation mode
With reference to figure 1, the general approach of the present invention about both system and method is shown.The customer of the system obtains container 200, container 200 is suitable for preserving body sample 230 and includes unique identification code 220.User is by his/her smart phone The application executed on 300 is by calling scanning function to fetch unique identification code.The application executed on smart phone 300 is only One authentication code is associated with multiple possible body sample tests.Then user is answered by what is executed on smart phone 300 It is tested with from multiple possible one or more body samples of body sample test selection.
Selection of the application executed on smart phone 300 unique identification code and one or more body sample tests Server 610 and/or the analytic unit for being associated and the information/request being transmitted to by wireless network 120 at network site Database 620 at 500.Preferably, for the transaction of the service(Payment)It must make that described information/request can be by analyzing Unit 500 is completed before obtaining.Then user is located in body sample 230 in container 200, and is for example taken using business delivering Business sends it to analytic unit 500.When container 200 is received at analytic unit 500, by calling analytic unit 500 The authentication code reader at place(It is not shown)Scanning function fetch the unique identification code 220 from container 200.
Analytic unit 500 is then using server 610 of the unique identification code from network site and/or from analysis Database 620 at unit 500 is fetched about the information that execute which body sample test to the body sample in container.
Then one or more body samples are executed to the body sample 230 in container 200 to test.Then one or more Body sample test result is stored on the server 610 at network site by associated with the unique identification code And/or on database 620.
Then, user can initiatively be notified by text on his/her smart phone or PUSH message.
Then, user utilize executed on smart phone using unique identification code 220 at network site It server 610 and/or is fetched from database 620 about one or more body samples to the body sample 230 in container 200 The information of test result.
Fig. 2 shows the containers of various embodiments of the present invention.The container includes base portion 205 and lid 210, the lid 210 It engages the base portion and coordinates to limit shell with the base portion 205, the shell is configured in closure(Fig. 2 B)Or it beats Open state(Fig. 2A).
The lid 210 includes usually opposite first surface side 211 and second surface side 212, and second surface side 212 Towards the base portion 205 in closed state.
In fig. 2, the unique identification code 220 is positioned on the second surface side of lid 210.This is in order to when appearance Device has been loaded body sample and has hidden the unique identification code when being therefore in closed state.
Fig. 3 shows the exemplary of the user interface 330 of the smart phone for using in the system and method for the present invention Embodiment.When pushing the round button 332 on touch screen 320, call scanning function to read unique identification code 220.Four A button 334-337 is around round button 332.The server and/or fetched from database that button 334 is used for from network site Information about one or more body sample test results.Its excess-three button 335-337 is for selecting different types of survey Examination.Only round button 332 is movable before unique identification code 220 has been identified.Unique identification code 220 After identified, round button 332, and activator button 335-337 are deactivated.When for the transaction of service(Payment)It has completed When, activator button 334 when test result is ready to.
With reference to
100 systems
120 wireless networks
200 containers
205 base portions
210 lids
211 first surface sides
212 second surface sides
220 unique identification codes
230 body samples
300 mobile/handheld computing devices
310 first identifier code readers
320 touch screens
330 user interfaces
332 round buttons
334 buttons
335 buttons
336 buttons
337 buttons
500 analysis component/analytic units
610 network sites
620 databases.

Claims (24)

1. a kind of system for obtaining test result from body sample(100), including:
Container(200), it is suitable for preserving body sample, the container(200)Including unique identification code;
Mobile/handheld computing device(300), including first identifier code reader;
Second identifier code reader(400);With
Analyze component(500), it is configured as executing the one or more test to body sample;
Wherein, the mobile/handheld computing device(300)Be configured as from multiple possible body samples tests recommend one or Multiple body sample tests;
Wherein, the mobile/handheld computing device(300)It is configured as from network site(610)The server at place and/or from number According to library(620)Data are fetched, the data include body sample associated with unique identification code(It is one or more)It surveys Test result.
2. system according to claim 1, wherein the mobile/handheld computing device(300)Be configured as one or The selection of user's selection of multiple body sample tests sends network site to(610)At the server and/or analytic unit at place Database(620), what the user selected selects and from the container suitable for preserving body sample(200)Unique mark generation Code is associated.
3. according to the system described in any one of claim 1-2, wherein the mobile/handheld computing device is configured to respond to It is inputted in from the user for the group selection being made of following items:Chronic conditions, family's genetic disease, age, nationality, race Property, gender, height, weight, body-mass index(BMI), body volume index(BVI), genotype, phenotype, disease, disease it is tight Weight degree, progression of disease rate, the measurement of Functional Capability, quality of life, intervention and remedial measure, and from the multiple possible One or more body sample tests are recommended in body sample test.
4. system according to any one of claim 1-3, wherein the analysis component(500)It is configured as future itself The test result of body sample is stored in container therein with body sample(200)On the unique identification code it is associated, And the test result is stored on the server at network site and/or is stored on the database.
5. according to the system described in any one of claim 1-4, wherein the mobile/handheld computing device(300)It is configured Selectively to fetch data associated with unique identification code, the unique identification code had previously utilized the shifting Dynamic/hand-held computing device(300)First identifier code reader it is identified.
6. system according to any one of claims 1-5, wherein the mobile/handheld computing device(300)It is intelligence Phone or tablet computer;And the wherein described unique identification code uses quick response(QR)Code or other matrixes(Two dimension) The form of bar code, other matrixes(Two dimension)Bar code can be by being programmed to identify the mobile electricity with processing array bar code The camera of words or tablet computer is read.
7. system according to any one of claims 1-5, wherein the mobile/handheld computing device(300)It is intelligence Phone or tablet computer;And the wherein described unique identification code uses radio frequency identification(RFID)The form of code, it is described to penetrate Frequency identifies(RFID)Code can be read by the radio frequency interface for being programmed to identify and handle the mobile phone of RFID or tablet computer It takes.
8. according to the system described in any one of claim 1-7, wherein the container(200)It is configured to sampling body sample This.
9. according to the system described in any one of claim 1-8, wherein the container(200)Including base portion(210)And lid (220), the lid(220)Engage the base portion(210)And with the base portion(210)Cooperation is to limit shell, the shell quilt It is configured at the state of closing or opening;
Wherein, the lid(220)Including usually opposite first surface side(221)With second surface side(222), and wherein institute State second surface side(222)Towards the base portion in closed state(210).
10. system according to claim 9, wherein the unique identification code is positioned in second surface side(222)On And/or it is located in base portion(210)The surface side towards shell on;And the wherein described unique identification code uses quick response (QR)Code or other matrixes(Two dimension)The form of bar code, other matrixes(Two dimension)Bar code can be by being programmed to identify It is read with the mobile phone of processing array bar code or the camera of tablet computer.
11. a kind of mobile/handheld computing device(300), including first identifier code reader;
Wherein, the mobile/handheld computing device(300)Be configured as from multiple possible body samples tests recommend one or Multiple body sample tests;
Wherein, the mobile/handheld computing device(300)It is configured as from network site(610)The server at place and/or from number According to library(620)Data are fetched, the data include body sample associated with unique identification code(It is one or more)It surveys Test result.
12. mobile/handheld computing device according to claim 11(300), wherein the mobile/handheld computing device (300)It is configured as the selection for user's selection that one or more body samples are tested to send network site to(610)Place Database at server and/or analytic unit(620), what the user selected selects and from suitable for preserving body sample Container(200)Unique identification code it is associated.
13. the mobile/handheld computing device according to any one of claim 11-12(300), wherein the movement/hand Computing device is held to be configured to respond to input from the user for the group selection being made of following items:Chronic conditions, family lose Pass disease, age, nationality, ethnicity, gender, height, weight, body-mass index(BMI), body volume index(BVI), base Because of type, phenotype, disease, disease severity, progression of disease rate, the measurement of Functional Capability, quality of life, intervenes and remedy and arrange It applies, and recommends one or more body sample tests from the multiple possible body sample test.
14. the mobile/handheld computing device according to any one of claim 11-13(300), wherein the movement/hand Hold computing device(300)It is configured as selectively fetching data associated with unique identification code, the unique mark generation Code had previously utilized the mobile/handheld computing device(300)First identifier code reader it is identified.
15. the mobile/handheld computing device according to any one of claim 11-14(300), wherein the movement/hand Hold computing device(300)It is smart phone or tablet computer;And the wherein described unique identification code uses quick response (QR)Code or other matrixes(Two dimension)The form of bar code, other matrixes(Two dimension)Bar code can be by being programmed to identify It is read with the mobile phone of processing array bar code or the camera of tablet computer.
16. the mobile/handheld computing device according to any one of claim 11-14(300), wherein the movement/hand Hold computing device(300)It is smart phone or tablet computer;And the wherein described unique identification code uses radio frequency identification (RFID)The form of code, the radio frequency identification(RFID)Code can by be programmed to identify and handle RFID mobile phone or The radio frequency interface of tablet computer is read.
17. a kind of method for obtaining test result from body sample includes the following steps:
The container for being suitable for preserving body sample is provided, the container includes unique identification code;
It is taken by the application executed on mobile/handheld computing device by calling the scanning function of mobile/handheld computing device Return the unique identification code, wherein the application executed on the mobile/handheld computing device is the unique identification code It is associated with multiple possible body sample tests;
It is selected from the multiple possible body sample test by the application executed on the mobile/handheld computing device One or more body sample tests;
One or more body samples are tested by mobile/handheld computing device handle is associated with the unique identification code The selection database that is transmitted to the server at network site and/or is transmitted at analytic unit;
Body sample is located in container;
By container transmission/transport analytic unit;
The container is received at the analytic unit;
By calling the scanning function of authentication code reader at the analytic unit unique mark is fetched from container Code;
Using the unique identification code pass is fetched from the server from network site and/or the database from analytic unit In the information that execute which body sample test to the body sample in container;
One or more body sample tests are executed to the body sample from container;
One or more body sample test results to the body sample from container are related to the unique identification code Connection, and be stored on the server at network site and/or on database;
Using described in being executed on the mobile/handheld computing device using the unique identification code from network position It the server at the place of setting and/or is fetched from database about one or more of bodies to the body sample from the container The information of sample test result.
18. method according to claim 17 further includes following steps:In response to the use from the group selection being made of following items Family inputs:Chronic conditions, family's genetic disease, age, nationality, ethnicity, gender, height, weight, body-mass index (BMI), body volume index(BVI), genotype, phenotype, disease, disease severity, progression of disease rate, Functional Capability Measurement, quality of life, intervention and remedial measure, and the application by being executed on the mobile/handheld computing device is from described more One or more body sample tests are recommended in a possible body sample test.
Further include following steps 19. according to the method described in any one of claim 17-18:By in the mobile/handheld meter It calculates the application executed on device and fetches data associated with unique identification code, the unique identification code had previously utilized The mobile/handheld computing device(300)First identifier code reader it is identified.
20. according to the method described in any one of claim 17-19, wherein the mobile/handheld computing device(300)It is Smart phone or tablet computer;And the wherein described unique identification code uses quick response(QR)Code or other matrixes (Two dimension)The form of bar code, other matrixes(Two dimension)Bar code can be by being programmed to identification and processing array bar code The camera of mobile phone or tablet computer is read.
21. according to the method described in any one of claim 17-19, wherein the mobile/handheld computing device(300)It is Smart phone or tablet computer;And the wherein described unique identification code uses radio frequency identification(RFID)The form of code, institute State radio frequency identification(RFID)Code can be connect by the radio frequency for the mobile phone or tablet computer for being programmed to identify and handle RFID Mouth is read.
22. according to the method described in any one of claim 17-21, wherein the container(200)It is configured to sampling body Sample.
23. according to the method described in any one of claim 17-22, wherein the container(200)Including base portion(210)With Lid(220), the lid(220)Engage the base portion(210)And with the base portion(210)Cooperation is to limit shell, the shell It is configured to be in and closes or opens state;
Wherein, the lid(220)Including usually opposite first surface side(221)With second surface side(222), and wherein institute State second surface side(222)Towards the base portion in closed state(210).
24. according to the method for claim 23, wherein the unique identification code is positioned in second surface side(222)On And/or it is located in base portion(210)The surface side towards shell on;And the wherein described unique identification code uses quick response (QR)Code or other matrixes(Two dimension)The form of bar code, other matrixes(Two dimension)Bar code can be by being programmed to identify It is read with the mobile phone of processing array bar code or the camera of tablet computer.
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CN112562865B (en) * 2021-02-18 2022-07-15 北京声智科技有限公司 Information association method, device, terminal and storage medium

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