CN108344743A - One kind being based on machine vision drug blister package defect inspection method and system - Google Patents

One kind being based on machine vision drug blister package defect inspection method and system Download PDF

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Publication number
CN108344743A
CN108344743A CN201810107074.3A CN201810107074A CN108344743A CN 108344743 A CN108344743 A CN 108344743A CN 201810107074 A CN201810107074 A CN 201810107074A CN 108344743 A CN108344743 A CN 108344743A
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China
Prior art keywords
image
machine vision
drug
blister package
detection method
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CN201810107074.3A
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Inventor
黄远民
易铭
杨伟航
杨元凯
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Foshan Polytechnic
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Foshan Polytechnic
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Priority to CN201810107074.3A priority Critical patent/CN108344743A/en
Publication of CN108344743A publication Critical patent/CN108344743A/en
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/84Systems specially adapted for particular applications
    • G01N21/88Investigating the presence of flaws or contamination
    • G01N21/8851Scan or image signal processing specially adapted therefor, e.g. for scan signal adjustment, for detecting different kinds of defects, for compensating for structures, markings, edges
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/84Systems specially adapted for particular applications
    • G01N21/88Investigating the presence of flaws or contamination
    • G01N21/8851Scan or image signal processing specially adapted therefor, e.g. for scan signal adjustment, for detecting different kinds of defects, for compensating for structures, markings, edges
    • G01N2021/8887Scan or image signal processing specially adapted therefor, e.g. for scan signal adjustment, for detecting different kinds of defects, for compensating for structures, markings, edges based on image processing techniques

Abstract

The invention discloses one kind being based on machine vision drug blister package detection method and system comprising following steps:Step 1, Image Acquisition acquire image information using on laser transmitter projects to packaged bubble-cap;Enhancing, recovery, coding and the greyscale transformation of step 2, Image Information Processing, including image carry out image the removal of noise;Step 3, image segmentation, threshold values setting;Step 4, Image edge tracking utilize Canny edge detection algorithms detection bubble-cap edge;Step 5 extracts characteristics of image, carries out threshold value setting to the image of decomposition, threshold values extracts the characteristics of image of corresponding region;Step 6, the color of extraction segmentation drug, position, size and shape;Step 7, select tablet position, size, shape and surface defect size tolerance;Step 8 stores standard form, tablet feature and tolerance;Step 9, it is tagged to defect tablet and corresponding bubble-cap;Step 10 finally carries out data storage.

Description

One kind being based on machine vision drug blister package defect inspection method and system
Technical field
The present invention relates to bubble-cap detection technique fields, more particularly to one kind to be lacked based on machine vision drug blister package Fall into detection method and system.
Background technology
The factor for influencing materia medica packaging quality includes mainly vacuole, tablet incompleteness and surface color.On the one hand traditional Contact type measurement limitation of the technology drug bubble-cap detection efficiency and accuracy of detection, on the other hand traditional offline, static measurement skill Art can not meet the requirement of modern measure again, cannot detect pharmaceutical packing defect in time, seriously affect materia medica packaging quality. If can not achieve, speed is fast, precision is high, online automatic detection, can reduce enterprises production efficiency, or even directly affect enterprise Economic benefit.In addition, traditional Key works Drug packing detection is manual operation, detection result and efficiency rely primarily on reviewer, people For influence factor is big, omission factor is high, the degree of automation is low.In addition, pure artificial detection operation there is also labor intensities big, work It is very low to make efficiency.
Therefore, the existing technology needs to be improved and developed.
Invention content
The purpose of the present invention is to provide one kind being based on machine vision drug blister package defect inspection method and system, purport Slow in the bubble-cap detection speed for solving existing Key works Drug packing, precision is low, and the degree of automation is low, and using the labour of artificial detection It is slight big, the low technical problem of efficiency.
Technical scheme is as follows:One kind being based on machine vision drug blister package detection method comprising following Step:
Step 1, Image Acquisition acquire image information using on laser transmitter projects to packaged bubble-cap;
Step 2, Image Information Processing, the enhancing of image, recovery, coding and greyscale transformation, using median filtering method to collecting Image carries out the removal of noise;
Step 3, image segmentation(Object or boundary), threshold values setting;
Step 4, Image edge tracking utilize Canny edge detection algorithms detection bubble-cap edge;
Step 5 extracts characteristics of image, carries out threshold value setting to the image of decomposition, threshold values extracts the characteristics of image of corresponding region;
Step 6, the color of extraction segmentation drug, position, size and shape;
Step 7, select tablet position, size, shape and surface defect size tolerance;
Step 8 stores standard form, tablet feature and tolerance;
Step 9, it is tagged to defect tablet and corresponding bubble-cap;
Step 10, data storage show corresponding inspection result simultaneously related defects information preservation in corresponding lane database Face.
It is described based on machine vision drug blister package detection method, wherein acquire image information in the step 1 Mode is to obtain corresponding artificial texture, then acquire image by industrial CCD camera on laser transmitter projects to drug bubble-cap Information.
Described is based on machine vision drug blister package detection method, wherein the industrial CCD camera passes through silk Bar is connect with servo motor, and drives down conversion camera site in servo motor.
It is described based on machine vision drug blister package detection method, wherein the median filter method of the step 2 It is:To pending current pixel, a template is selected, which is its neighbouring several pixels composition, to the picture of template Element is ascending to be ranked up, then the value of original pixel is substituted with the intermediate value of template.
It is described based on machine vision drug blister package detection method, wherein the template is weight coefficient matrix template, Formula is:
g=median[(x-1,y-1)+f(x,y-1)+f(x+1,y-1)+f(x-1,y)+f(x,y)+f(x+1,y) +f(x-1,y+ 1)+f(x,y+1)+f(x+1,y+1)]。
It is described based on machine vision drug blister package detection method, wherein the step of the Canny edge detection algorithms It is rapid as follows:
The first step:Noise is eliminated in such a way that 2D gaussian filtering templates carry out convolution to carry out noise elimination;
Second step:The finite difference that the amplitude of calculating gradient and direction use single order local derviation carries out correlation computations,
The partial derivative in two directions of gradation of image is found using derivative operator (such as Prewitt operators, Sobel operators) (Gx, Gy), and find out the size of gradient;
Third walks:The direction of gradient is calculated using the result of second step;Further according to formula:;It obtains Edge direction, so that it may the gradient direction at edge is broadly divided into following four direction:Horizontal, vertical, 45 degree and 135 degree of sides To;Then the adjacent pixels in this pixel gradient direction are found according to the direction of gradient;
4th step:Edge is detected and connected with dual threashold value-based algorithm;Two threshold values are calculated using accumulative histogram.
It is described based on machine vision drug blister package detection method, wherein it is described Step 5: Step 6: Step 7: Step 8 and step 10, which carry, to be realized by machine vision software Halcon.
A kind of detecting system based on machine vision drug blister package detection method comprising laser lighting light source is provided Laser emitter, photoelectric sensor switch, ccd image sensor, image processor, control unit, transmission device, machinery positioning Device and executive device;Described control unit respectively with transmission device, mechanical positioner, executive device, image processor, swash Optical transmitting set, photoelectric sensor switch are connected with ccd image sensor;The executive device is connect with industrial CCD camera.
The detecting system based on machine vision drug blister package detection method, wherein described image processor Including image pre-processing unit, image segmentation unit, the feature extraction unit for extracting characteristics of image, the classification for carrying out image classification Unit and the image analysis of mechanism unit for carrying out image analysis;Described image analysis of mechanism unit is connect with control unit;It is described Image pre-processing unit is connect with industrial CCD camera.
The detecting system based on machine vision drug blister package detection method, wherein the industrial CCD camera By the principle of opto-electronic conversion it is digital signal by photoelectric signal transformation by the image information of acquisition, is then transferred to image and locates in advance Manage unit.
Beneficial effects of the present invention:
One, by the way of forming artificial texture on laser transmitter projects to drug bubble-cap, effectively enhance the detected sun The orderliness feature of energy silicon chip.
Two, it is calculated using image preprocessing used by the image pre-processing unit in drug blister package vision detection system Method, including image smoothing, image gray-scale transformation, histogram equalization processing and modified medium filtering, to enhance image matter Amount is laid a good foundation to improve detection reliability.
Three, by the way that lead screw and servo motor is arranged, during drug bubble-cap defects detection, industrial CCD camera is being adopted The image process for collecting drug bubble-cap, according to the type of drug bubble-cap to be detected, host computer send the corresponding type of drug bubble-cap to In PLC, screw rod transmission is driven by servo motor, camera is moved to corresponding position, is realized to different size drug blister pack The Image Acquisition of dress, it is easy to use.
Four, using controlling screw rod transmission through servo motor, lead screw drives slide block movement again, to realize to various specifications drug The Image Acquisition of bubble-cap, high degree of automation, accurate positioning.
Description of the drawings
Fig. 1 is the step block diagram of the present invention.
Fig. 2 is the structural schematic diagram of the present invention.
Fig. 3 is the functional block diagram of image processor.
Fig. 4 is the work flow diagram of the present invention.
Specific implementation mode
To make the objectives, technical solutions, and advantages of the present invention clearer and more explicit, develop simultaneously embodiment pair referring to the drawings The present invention is further described.
As shown in Figure 1, the invention discloses one kind being based on machine vision drug blister package detection method comprising following Step:
Step 1, Image Acquisition acquire image information using on laser transmitter projects to packaged bubble-cap;
Step 2, Image Information Processing, the enhancing of image, recovery, coding and greyscale transformation, using median filtering method to collecting Image carries out the removal of noise;
Step 3, image segmentation(Object or boundary), threshold values setting;
Step 4, Image edge tracking utilize Canny edge detection algorithms detection bubble-cap edge;
Step 5 extracts characteristics of image, carries out threshold value setting to the image of decomposition, threshold values extracts the characteristics of image of corresponding region;
Step 6, the color of extraction segmentation drug, position, size and shape;
Step 7, select tablet position, size, shape and surface defect size tolerance;
Step 8 stores standard form, tablet feature and tolerance;
Step 9, it is tagged to defect tablet and corresponding bubble-cap;
Step 10, data storage show corresponding inspection result simultaneously related defects information preservation in corresponding lane database Face.
After the above method, compared with prior art, the present embodiment uses laser transmitter projects to method of the invention Onto drug bubble-cap, to obtain corresponding image artificial texture, effectively enhancing is detected the orderliness feature of drug bubble-cap.Together When, in the process for removing noise to image in addition to using median filtering method is improved, effectively reducing error, improving the reliable of detection Property.
As shown in Fig. 2, the schematic device that detection method uses in the present invention comprising camera bellows 1, conveyer belt 2, industry CCD camera 3 and laser emitter 4, the laser emitter 4 and industrial CCD camera 3 are separately mounted to the top of camera bellows 1, are used for Image information is acquired, the drug 5 is placed on the conveyer belt transmission past, is collected the image of drug bubble-cap during transmission Then the image information of acquisition is fed back to image processor, is handled by information;It is single that handling result is transferred to control again Member is stored in into row label, and by testing result in corresponding database by control unit control executive device.
It is described based on machine vision drug blister package detection method, wherein acquire image information in the step 1 Mode is to obtain corresponding artificial texture, then acquire image by industrial CCD camera on laser transmitter projects to drug bubble-cap Information.
Described is based on machine vision drug blister package detection method, wherein the industrial CCD camera passes through silk Bar is connect with servo motor, and drives down conversion camera site in servo motor.
It is described based on machine vision drug blister package detection method, wherein the median filter method of the step 2 It is:To pending current pixel, a template is selected, which is its neighbouring several pixels composition, to the picture of template Element is ascending to be ranked up, then the value of original pixel is substituted with the intermediate value of template.
It is described based on machine vision drug blister package detection method, wherein the template is weight coefficient matrix template, Formula is:
g=median[(x-1,y-1)+f(x,y-1)+f(x+1,y-1)+f(x-1,y)+f(x,y)+f(x+1,y) +f(x-1,y+ 1)+f(x,y+1)+f(x+1,y+1)]。
The present invention can inhibit image effect very well by this method, and the clear analysis degree of image is kept substantially, ensure that The picture quality of acquisition.
In order to obtain ideal tablet image border, the present invention is using Canny operators to image edge processing;It is described The step of Canny edge detection algorithms, is as follows:
The first step:Noise is eliminated in such a way that 2D gaussian filtering templates carry out convolution to carry out noise elimination;
Second step:The finite difference that the amplitude of calculating gradient and direction use single order local derviation carries out correlation computations,
The partial derivative in two directions of gradation of image is found using derivative operator (such as Prewitt operators, Sobel operators) (Gx, Gy), and find out the size of gradient;
Third walks:The direction of gradient is calculated using the result of second step;Further according to formula:;It obtains Edge direction, so that it may the gradient direction at edge is broadly divided into following four direction:Horizontal, vertical, 45 degree and 135 degree of sides To;Then the adjacent pixels in this pixel gradient direction are found according to the direction of gradient;
4th step:Edge is detected and connected with dual threashold value-based algorithm;Two threshold values are calculated using accumulative histogram.
It is described based on machine vision drug blister package detection method, wherein it is described Step 5: Step 6: Step 7: Step 8 and step 10, which carry, to be realized by machine vision software Halcon.
Above-mentioned HALCON is the machine vision algorithm packet of a set of perfect standard of German MVtec companies exploitation, is possessed Widely used machine vision Integrated Development Environment.It has saved product cost, shortens software development cycle -- HALCON spirits Framework living is convenient for machine vision, the quick exploitation of medical image and image analysis application.In Europe and the industrial quarters of Japan It has been to generally acknowledge the Machine Vision softwares with best efficiency.
A kind of detecting system based on machine vision drug blister package detection method comprising laser lighting light source is provided Laser emitter, photoelectric sensor switch, ccd image sensor, image processor, control unit, transmission device, machinery positioning Device and executive device;Described control unit respectively with transmission device, mechanical positioner, executive device, image processor, swash Optical transmitting set, photoelectric sensor switch are connected with ccd image sensor;The executive device is connect with industrial CCD camera.
The detecting system based on machine vision drug blister package detection method, wherein described image processor Including image pre-processing unit, image segmentation unit, the feature extraction unit for extracting characteristics of image, the classification for carrying out image classification Unit and the image analysis of mechanism unit for carrying out image analysis;Described image analysis of mechanism unit is connect with control unit;It is described Image pre-processing unit is connect with industrial CCD camera.
The detecting system based on machine vision drug blister package detection method, wherein the industrial CCD camera By the principle of opto-electronic conversion it is digital signal by photoelectric signal transformation by the image information of acquisition, is then transferred to image and locates in advance Manage unit.
As shown in figure 3, the basic function figure of the image processor in the present invention is disclosed, including image input, being used for will Photoelectric signal transformation is at digital signal;Image preprocessing carries out image enhancement, coding, greyscale transformation and medium filtering;Image point It cuts, is used for detection image boundary;Characteristics of image is extracted, image carries out classification and image analysis of mechanism.
As shown in figure 4, the present invention work flow diagram it is as follows, be first begin to, read read standard form, drug characteristic and Tolerance;There is trigger signal when then looking at, if having, captures drug bubble-cap image to be detected, it is no, then it returns and whether touches Alerting phase;Then image procossing and correction are carried out, then carries out image segmentation, extraction drug position, size, shape and face Color;And carry out characteristic value comparison with standard form;After comparison, it was found that defective drug, stamps defective drug corresponding Label;Ultimately produce the correspondence flaw indication of drug;Then judge whether to continue to detect, it is no, then terminate;It is touched if so, returning Alerting phase.
Beneficial effects of the present invention:
One, by the way of forming artificial texture on laser transmitter projects to drug bubble-cap, effectively enhance the detected sun The orderliness feature of energy silicon chip.
Two, it is calculated using image preprocessing used by the image pre-processing unit in drug blister package vision detection system Method, including image smoothing, image gray-scale transformation, histogram equalization processing and modified medium filtering, to enhance image matter Amount is laid a good foundation to improve detection reliability.
Three, by the way that lead screw and servo motor is arranged, during drug bubble-cap defects detection, industrial CCD camera is being adopted The image process for collecting drug bubble-cap, according to the type of drug bubble-cap to be detected, host computer send the corresponding type of drug bubble-cap to In PLC, screw rod transmission is driven by servo motor, camera is moved to corresponding position, is realized to different size drug blister pack The Image Acquisition of dress, it is easy to use.
Four, using controlling screw rod transmission through servo motor, lead screw drives slide block movement again, to realize to various specifications drug The Image Acquisition of bubble-cap, high degree of automation, accurate positioning.
It is manual operation the present invention overcomes the detection of traditional Key works Drug packing, detection result and efficiency rely primarily on identifier Member, the defects such as artifical influence factor is big, omission factor is high, the degree of automation is low.Exist in addition, overcoming in pure artificial detection operation Labor intensity greatly and ineffective technical problem.
It should be understood that the application of the present invention is not limited to the above for those of ordinary skills can With improvement or transformation based on the above description, all these modifications and variations should all belong to the guarantor of appended claims of the present invention Protect range.

Claims (10)

1. one kind being based on machine vision drug blister package detection method, which is characterized in that include the following steps:
Step 1, Image Acquisition acquire image information using on laser transmitter projects to packaged bubble-cap;
Step 2, Image Information Processing, the enhancing of image, recovery, coding and greyscale transformation, using median filtering method to collecting Image carries out the removal of noise;
Step 3, image segmentation(Object or boundary), threshold values setting;
Step 4, Image edge tracking utilize Canny edge detection algorithms detection bubble-cap edge;
Step 5 extracts characteristics of image, carries out threshold value setting to the image of decomposition, threshold values extracts the characteristics of image of corresponding region;
Step 6, the color of extraction segmentation drug, position, size and shape;
Step 7, select tablet position, size, shape and surface defect size tolerance;
Step 8 stores standard form, tablet feature and tolerance;
Step 9, it is tagged to defect tablet and corresponding bubble-cap;
Step 10, data storage show corresponding inspection result simultaneously related defects information preservation in corresponding lane database Face.
2. according to claim 1 be based on machine vision drug blister package detection method, which is characterized in that the step It is to obtain corresponding artificial texture, then pass through work on laser transmitter projects to drug bubble-cap that image information mode is acquired in one Industry CCD camera acquires image information.
3. according to claim 2 be based on machine vision drug blister package detection method, which is characterized in that described Industrial CCD camera is connect by lead screw with servo motor, and drives down conversion camera site in servo motor.
4. according to claim 1 be based on machine vision drug blister package detection method, which is characterized in that the step Two median filter method is:To pending current pixel, it is its several neighbouring pixel to select a template, the template Composition, it is ascending to the pixel of template to be ranked up, then the value of original pixel is substituted with the intermediate value of template.
5. according to right want described in 4 based on machine vision drug blister package detection method, which is characterized in that the template is Weight coefficient matrix template, formula are:
g=median[(x-1,y-1)+f(x,y-1)+f(x+1,y-1)+f(x-1,y)+f(x,y)+f(x+1,y) +f(x-1,y+ 1)+f(x,y+1)+f(x+1,y+1)]。
6. according to claim 1 be based on machine vision drug blister package detection method, which is characterized in that described The step of Canny edge detection algorithms, is as follows:
The first step:Noise is eliminated in such a way that 2D gaussian filtering templates carry out convolution to carry out noise elimination;
Second step:The finite difference that the amplitude of calculating gradient and direction use single order local derviation carries out correlation computations,
The partial derivative in two directions of gradation of image is found using derivative operator (such as Prewitt operators, Sobel operators) (Gx, Gy), and find out the size of gradient;
Third walks:The direction of gradient is calculated using the result of second step;Further according to formula:;Side is obtained Edge direction, so that it may the gradient direction at edge is broadly divided into following four direction:Horizontal, vertical, 45 degree and 135 degree of sides To;Then the adjacent pixels in this pixel gradient direction are found according to the direction of gradient;
4th step:Edge is detected and connected with dual threashold value-based algorithm;Two threshold values are calculated using accumulative histogram.
7. according to claim 1 be based on machine vision drug blister package detection method, which is characterized in that the step Five, Step 6: Step 7: step 8 and step 10, which carry, to be realized by machine vision software Halcon.
8. a kind of detection system based on machine vision drug blister package detection method as described in claim 1-7 any one System, which is characterized in that laser emitter, photoelectric sensor switch, ccd image sensor, figure including providing laser lighting light source As processor, control unit, transmission device, mechanical positioner and executive device;Described control unit respectively with transmission device, Mechanical positioner, executive device, image processor, laser emitter, photoelectric sensor switch are connected with ccd image sensor; The executive device is connect with industrial CCD camera.
9. the detecting system according to claim 8 based on machine vision drug blister package detection method, feature exist In, described image processor include image pre-processing unit, image segmentation unit, the feature extraction unit for extracting characteristics of image, It carries out the taxon of image classification and carries out the image analysis of mechanism unit of image analysis;Described image analysis of mechanism unit with Control unit connects;Described image pretreatment unit is connect with industrial CCD camera.
10. the detecting system according to claim 1 based on machine vision drug blister package detection method, feature exist In, photoelectric signal transformation is digital signal by the principle of opto-electronic conversion by the industrial CCD camera by the image information of acquisition, It is then transferred to image pre-processing unit.
CN201810107074.3A 2018-02-02 2018-02-02 One kind being based on machine vision drug blister package defect inspection method and system Pending CN108344743A (en)

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Application publication date: 20180731