CN108344736A - A kind of indicating piece and preparation method for detecting wet packet - Google Patents
A kind of indicating piece and preparation method for detecting wet packet Download PDFInfo
- Publication number
- CN108344736A CN108344736A CN201810101522.9A CN201810101522A CN108344736A CN 108344736 A CN108344736 A CN 108344736A CN 201810101522 A CN201810101522 A CN 201810101522A CN 108344736 A CN108344736 A CN 108344736A
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- Prior art keywords
- indicating piece
- wet packet
- carrier layer
- layer
- indicating
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
- G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
- G01N21/78—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
- G01N21/81—Indicating humidity
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- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Plasma & Fusion (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
Abstract
The invention discloses a kind of indicating pieces and preparation method for detecting wet packet, and the component of the composition indicating piece includes the dye carrier of 150 200 molar parts, four water nickel acetates of 78 molar parts；The sodium hydroxide of the dimethylglyoxime of 1 molar part and 10 13 molar parts.Indicating piece is made by following steps, including：1 first takes the dye carrier after grinding to be added in Ni-acetate solution, stirs evenly rear washing filtering, drying, obtains powder mixture A；Then powder mixture A is added to dimethylglyoxime with the mixed solution of sodium hydroxide composition, washing, drying obtain the component of Target indication piece；The indicating piece with the fit depressions in carrier layer finally is made in obtained indicator component, and is pressed together in carrier layer and transparent fixed bed.The prepared indicating piece for detection is not only simple in structure stabilization, can repeatedly use, and color change depth can be facilitated to carry out the wet packet degree of semi-quantitative analysis.
Description
Technical field
The invention belongs to medical material safety testing fields, and in particular to a kind of indicating piece and preparation for detecting wet packet
Method.
Background technology
For multiplex medical instruments sterilization method, adoptable sterilizing methods have pressuresteam sterilization, ethylene oxide sterilizing,
Hot air sterilization, hydrogen peroxide low-temperature plasma sterilizing etc..The most commonly used is steams to go out in medical institutions at different levels at present
Bacterium, the sterilization method is also the most reliable, and use is most extensive.As the department for carrying out cleaning and sterilizing sterilizing to multiplexing instrument, hospital
Disinfection and supply center can often encounter " wet packet " phenomenon when carrying out everyday stress steam sterilizing to package.Wet packet destroys penetrating
Property ensure the biological barrier performance of material, so that the inside and outside continuous passage for forming microbial growth of package is become larger, be easy to cause in packet
Article is increased the risk of patient's postoperative infection by the pollution again of microorganism.Therefore it needs the present invention to propose one kind to be used for
The quickly chemical indicating piece and preparation method thereof of the judgement wet packet of steam sterilizing.
Invention content
In view of the above-mentioned problems, the present invention proposes a kind of indicating piece and preparation method for detecting wet packet.
It realizes above-mentioned technical purpose, reaches above-mentioned technique effect, the invention is realized by the following technical scheme：
A kind of indicating piece for detecting wet packet, the component of the composition indicating piece include：
The dye carrier of 150-200 molar parts；
Four water nickel acetates of 7-8 molar parts；
The dimethylglyoxime of 1 molar part；With
The sodium hydroxide of 10-13 molar parts.
As a further improvement on the present invention, the dye carrier is neutral alumina, silica, zirconium oxide, oxidation
Any one or two kinds of combinations of tin microballoon.
As a further improvement on the present invention, the indicating piece is made arbitrary in powdery, sheet, spherical or pearl
It is a kind of.
As a further improvement on the present invention, the indicating piece is placed on a carrier layer, is set in the carrier layer
Have accommodate indicating piece and with the matched groove of its shape；Include the groove described at least three in the carrier layer, it is described
Carrier layer be any one of copper foil, aluminium foil, silver foil or tinfoil paper metal foil.
As a further improvement on the present invention, the top of the carrier layer for being loaded with indicating piece sequentially covers one layer thoroughly
Bright fixed bed.
As a further improvement on the present invention, further include label layer, the label layer is connected with transparent fixed bed, described
Label layer be equipped with transparent window corresponding with the position of groove.
As a further improvement on the present invention, the two sides of the carrier layer or label layer waits carrying one layer of high-temperature plastic
Layer, the long-term heatproof section of glue-line are heatproof time >=30min at -40 DEG C~140 DEG C, 140 DEG C.
A kind of indicating piece method preparing wet packet, includes the following steps：
1) it takes the dye carrier after grinding to be added in Ni-acetate solution, stirs evenly rear washing filtering, drying, obtain powder
Body mixture A；
2) powder mixture A is added to dimethylglyoxime with the mixed solution of sodium hydroxide composition, washing, drying obtain
To the component of Target indication piece；
3) indicating piece with the fit depressions in carrier layer is made in obtained indicator component, and is pressed together on carrier
In layer and transparent fixed bed.
As a further improvement on the present invention, in step 1), the drying temperature is 90-110 DEG C, and the time of drying is
20-25min。
As a further improvement on the present invention, in step 2), the drying temperature is 112-118 DEG C, the time of drying
For 45-50min.
Beneficial effects of the present invention：
1. stable structure, the high temperature and humidity high pressure in sterilization process will not destroy the physics knot of humidity detection Chemical indicative card
Structure.
2. interpretation is convenient, can out of packet outer simulation packet wet packet situation, using the aluminium foil with two-sided high-temperature plastic, when use
Release paper can be directly removed, it is not only easy to use but also reusable.
3. being not in fade or return color after indicating piece sterilizing, the present invention is the face by humidity detection Chemical indicative card
Color change come reflect sterilizing the later stage steam moisture, can easily be according to color change depth come the wet packet degree of semi-quantitative analysis.
Description of the drawings
Fig. 1 is the structural schematic diagram of label of the present invention；
Fig. 2 is overlooking structure diagram of the present invention；
Fig. 3 is side structure schematic view of the present invention；
Wherein：1- label layers, 2- transparent windows, the transparent fixed beds of 3-, 4- indicating pieces, 5- grooves, 6- carrier layers.
Specific implementation mode
In order to make the purpose , technical scheme and advantage of the present invention be clearer, with reference to embodiments, to the present invention
It is further elaborated.It should be appreciated that the specific embodiments described herein are merely illustrative of the present invention, it is not used to
Limit the present invention.
The application principle of the present invention is explained in detail below in conjunction with the accompanying drawings.
Prepared by the present invention as shown in Figs. 1-3 it is a kind of for detect sterilize after wet packet humidity indicating piece 4, it is described
Indicating piece 4 be encapsulated between transparent fixed bed and carrier layer 6, the carrier layer 6 be equipped with place indicating piece 4 groove 5
In.
The component of the indicating piece 4 is according to the dye carrier that molar ratio includes 150-200 parts, 7-8 parts of four water nickel acetates,
The sodium hydroxide of 1 part of dimethylglyoxime and 10-13 part.Wherein, the dye carrier is neutral alumina, silica, oxidation
Any one or two kinds of combinations of zirconium, tin oxide microballoon.
The component is weighed into raw material according to the molar ratio of regulation and carries out configuration by the following method and prepares indicating piece
4, step includes：
1) it is added to after grinding dye carrier in Ni-acetate solution, stirs evenly rear washing filtering, later in 90-
20-25min is dried at a temperature of 110 DEG C, obtains powder mixture A.
2) powder mixture A is added to dimethylglyoxime with the mixed solution of sodium hydroxide composition, be thoroughly mixed
It is washed after 1.9-2.1min, most afterwards through drying 45-50min at 112-118 DEG C, obtains the component of required Target indication piece 4.
3) any one shape in powdery, sheet, spherical or pearl, the shape is made in obtained indicator component
With the 5 matched indicating piece 4 of groove in carrier layer 6, and it is pressed together in carrier layer 6 and transparent fixed bed.
The carrier layer 6 is metal foil, and the metal foil is using any one of copper foil, aluminium foil, silver foil or tinfoil paper, thickness
For 0.05~0.12mm.Using thickness it is 0.08mm, length 4cm in a kind of embodiment of the present invention, width is
The aluminium foil of 1.4cm is provided at least three groove 5 on the aluminium foil.
The transparent fixed bed is transparent membrane, and the transparent membrane material is more than 87% using visible light synthesis light transmittance
PET one-side band glue, thickness section is 0.04-0.12mm, and the long-term heatproof section of the glue-line is -40 DEG C~140 DEG C, 140 DEG C
Corresponding heatproof time >=30min.
In order to distinguish when use, the top of the indicating piece 4 has also attached label layer 1, on the label layer 1
Equipped with transparent window corresponding with the position of groove 52.
During being detected humidity using indicating piece 4, needs to attach indicating piece 4 and waiting for the package in sterilizing
Outside, therefore the two sides of the carrier layer 6 and label layer 1 waits carrying one layer of high temperature resistant glue-line, glue-line resistance to warm area for a long time
Between for heatproof time >=30min at -40 DEG C~140 DEG C, 140 DEG C, one layer of Ge Laxin has been attached on the glue-line of lateral surface
Release paper is protected.
Due to wrapping up using pressuresteam sterilization, heatproof of the transparent membrane of the present invention at 140 DEG C
Time is 60min, and heatproof time of the high temperature resistant glue-line at 140 DEG C is 120min.Under high temperature in sterilization process, structure
It is not easy to be destroyed.
In detection process and after detection, the indicating piece 4 by being fixed by the surface with viscous being stained with property,
Indicating piece 4 is not easy to shake the integrality for remaining structure.So that indicating piece 4 has reusing.
The indicating piece 4 that disc-shaped is made is attached and is sterilized superscribing, according to application by a kind of embodiment of the present invention
The variation that 4 color of indicating piece under different sterilising temps and time circulation process is observed by transparent window 2 judges sterilization process
In degree of drying.The indicating piece 4 is ecru before sterilizing, if the drying of sterilizing later stage is not thorough, indicating piece 4 can be by cream colour
Discoloration is pink, if dry thorough, wet sensitive mixture can become crocus from ecru.Also even wet packet monitoring chemistry instruction
Card is designated as pink, then the package wraps up for wet packet.
Under the conditions of 1 pressuresteam sterilization of table, the color change of different drying times corresponding wet packet indicating piece
Using such as table 1, prepared wet packet indicating piece can be recycled at least on 10 under the sterilising conditions.
The above shows and describes the basic principles and main features of the present invention and the advantages of the present invention.The technology of the industry
Personnel are it should be appreciated that the present invention is not limited to the above embodiments, and the above embodiments and description only describe this
The principle of invention, without departing from the spirit and scope of the present invention, various changes and improvements may be made to the invention, these changes
Change and improvement all fall within the protetion scope of the claimed invention.The claimed scope of the invention by appended claims and its
Equivalent thereof.
Claims (10)
1. a kind of indicating piece for detecting wet packet, the component of the composition indicating piece include：
The dye carrier of 150-200 molar parts；
Four water nickel acetates of 7-8 molar parts；
The dimethylglyoxime of 1 molar part；With
The sodium hydroxide of 10-13 molar parts.
2. a kind of indicating piece for detecting wet packet according to claim 1, it is characterised in that：The dye carrier is
Any one or two kinds of combinations of neutral alumina, silica, zirconium oxide, tin oxide microballoon.
3. a kind of indicating piece for detecting wet packet according to claim 1, it is characterised in that：By the indicating piece system
Any one in powdering, sheet, spherical or pearl.
4. a kind of indicating piece for detecting wet packet according to claim 3, it is characterised in that：The indicating piece is put
Set on a carrier layer, the carrier layer be equipped with accommodate indicating piece and with the matched groove of its shape；The carrier layer
Upper includes the groove described at least three, and the carrier layer is any one of copper foil, aluminium foil, silver foil or tinfoil paper metal foil.
5. a kind of indicating piece for detecting wet packet according to claim 4, it is characterised in that：Described is loaded with indicating piece
The top of carrier layer sequentially cover layer of transparent fixed bed.
6. a kind of indicating piece for detecting wet packet according to claim 5, it is characterised in that：Further include label layer, institute
The label layer stated is connected with transparent fixed bed, and the label layer is equipped with transparent window corresponding with the position of groove.
7. a kind of indicating piece for detecting wet packet according to claim 4 or 6, it is characterised in that：The carrier layer
Or the two sides of label layer waits carrying one layer of high temperature resistant glue-line, the long-term heatproof section of glue-line is at -40 DEG C~140 DEG C, 140 DEG C
The heatproof time >=30min.
8. a kind of preparing a kind of indicating piece method for detecting wet packet of claim 1-5 any one of them, including following step
Suddenly：
1) it takes the dye carrier after grinding to be added in Ni-acetate solution, stirs evenly rear washing filtering, drying, it is mixed to obtain powder
Close object A；
2) powder mixture A is added to dimethylglyoxime with the mixed solution of sodium hydroxide composition, washing, drying obtain mesh
Mark the component of indicating piece；
3) indicating piece with the fit depressions in carrier layer is made in obtained indicator component, and be pressed together on carrier layer and
In transparent fixed bed.
9. a kind of preparing a kind of indicating piece method for detecting wet packet according to any one of claims 8, it is characterised in that：Step 1)
In, the drying temperature is 90-110 DEG C, and the time of drying is 20-25min.
10. a kind of preparing a kind of indicating piece method for detecting wet packet according to any one of claims 8, it is characterised in that：Step 2)
In, the drying temperature is 112-118 DEG C, and the time of drying is 45-50min.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810101522.9A CN108344736A (en) | 2018-02-01 | 2018-02-01 | A kind of indicating piece and preparation method for detecting wet packet |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810101522.9A CN108344736A (en) | 2018-02-01 | 2018-02-01 | A kind of indicating piece and preparation method for detecting wet packet |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN108344736A true CN108344736A (en) | 2018-07-31 |
Family
ID=62958809
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810101522.9A Pending CN108344736A (en) | 2018-02-01 | 2018-02-01 | A kind of indicating piece and preparation method for detecting wet packet |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN108344736A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111621200A (en) * | 2020-04-23 | 2020-09-04 | 南京巨鲨显示科技有限公司 | Humidity-sensitive color-changing ink, wet package monitoring label and preparation method thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN201643032U (en) * | 2010-03-22 | 2010-11-24 | 淄博亘泽精细化工有限公司 | Water-proof and impermeable damp and hot sterilization chemical indicator |
| CN105074455A (en) * | 2013-03-15 | 2015-11-18 | 3M创新有限公司 | Post-steam sterilization moisture-indicating articles |
| CN106492251A (en) * | 2016-11-22 | 2017-03-15 | 南京巨鲨显示科技有限公司 | A kind of steam sterilization comprehensively indicates to sign |
-
2018
- 2018-02-01 CN CN201810101522.9A patent/CN108344736A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN201643032U (en) * | 2010-03-22 | 2010-11-24 | 淄博亘泽精细化工有限公司 | Water-proof and impermeable damp and hot sterilization chemical indicator |
| CN105074455A (en) * | 2013-03-15 | 2015-11-18 | 3M创新有限公司 | Post-steam sterilization moisture-indicating articles |
| CN106492251A (en) * | 2016-11-22 | 2017-03-15 | 南京巨鲨显示科技有限公司 | A kind of steam sterilization comprehensively indicates to sign |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111621200A (en) * | 2020-04-23 | 2020-09-04 | 南京巨鲨显示科技有限公司 | Humidity-sensitive color-changing ink, wet package monitoring label and preparation method thereof |
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| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20180731 |
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| RJ01 | Rejection of invention patent application after publication |