CN108334868A - A kind of pulse analysis method based on PPG signals and image enhancement - Google Patents
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Abstract
本发明涉及一种基于PPG(光电容积脉搏波描记法)信号和图像增强的脉象分析方法,包括以下步骤:采集人脸视频图像;对视频图像进行增强处理,消除低光照的影响;视频的RGB通道分离;利用ICA算法处理;G通道相关性分析,获取PPG脉搏波信号;对含噪PPG脉搏波信号进行去噪;求PPG脉搏波信号的各特征点;将脉搏波的特征值输入KNN算法,输出脉象分类结果;分类结果与标准数据库对比并判断病症。本发明提供的一种基于PPG信号和图像增强方法的脉象分析方法,将传统中医的脉象理论同计算机技术相结合,既能够有效的实现客观化、定量化的脉象分析,又避免了采集时低光照环境对脉象分析的影响。
The present invention relates to a kind of pulse analysis method based on PPG (photoplethysmography) signal and image enhancement, comprising the following steps: collecting face video images; enhancing the video images to eliminate the influence of low light; Channel separation; use ICA algorithm to process; G channel correlation analysis to obtain PPG pulse wave signal; denoise the noisy PPG pulse wave signal; find each characteristic point of PPG pulse wave signal; input the characteristic value of pulse wave into KNN algorithm , output the classification result of pulse condition; compare the classification result with the standard database and judge the disease. A pulse condition analysis method based on PPG signal and image enhancement method provided by the present invention combines the pulse condition theory of traditional Chinese medicine with computer technology, which can effectively realize objective and quantitative pulse condition analysis, and avoids the low Effect of lighting environment on pulse condition analysis.
Description
技术领域technical field
本发明涉及图像处理和信号处理领域,具体来说,是一种基于PPG信号和图像增强的脉象分析方法。The invention relates to the field of image processing and signal processing, in particular to a pulse condition analysis method based on PPG signal and image enhancement.
背景技术Background technique
脉象是脉搏的形势与动态,是中国古代判断人体病症的主要依据。当今医学对于人体脉象的检测主要有两种方式,一是通过手指放至人体桡动脉处感受脉搏的变化,即传统中医把脉的方法,二是通过传感器代替手指感知桡动脉处脉搏的搏动变化。前者需要专业的中医人员进行检测,后者大多是把适当的传感器置于被测部位,将脉搏的搏动转换为电信号,再输入放大电路,将微弱的信号用计算机处理,在对脉搏波进行分析诊断。此方法需要复杂的仪器设备且价格昂贵,不方便携带及家庭使用。本文尝试通过分析普通计算机摄像头采集的人脸视频信息,获得人体脉象特性,进而实现利用普通计算机系统检测人体健康状况。Pulse condition is the situation and dynamics of the pulse, and it is the main basis for judging human diseases in ancient China. Today's medicine mainly has two ways to detect the pulse of the human body. One is to feel the change of the pulse by putting the finger on the radial artery of the human body, that is, the traditional Chinese medicine method of feeling the pulse, and the other is to use the sensor instead of the finger to sense the pulse change of the radial artery. The former requires professional Chinese medicine personnel to detect, while the latter usually puts appropriate sensors on the measured part, converts the pulsation of the pulse into an electrical signal, and then inputs it into an amplifier circuit, processes the weak signal with a computer, and then processes the pulse wave. Analysis and diagnosis. This method requires complex instruments and equipment and is expensive, and it is inconvenient to carry and use at home. This paper attempts to obtain the pulse characteristics of the human body by analyzing the face video information collected by ordinary computer cameras, and then realize the detection of human health status using ordinary computer systems.
目前技术关注的重心较偏向于脉象信号采集仪器、方法的改进,或者是针对脉象信号处理和分析的某一环节进行深入分析研究,缺乏一定的前后连贯性、系统性的脉象检测分析方法,或者是没有对一些会影响脉象检测的因素作适当的处理,比如光照。因此对于一种完备的、系统的、严谨的脉象分析方法的提出是极为必要的。At present, the focus of technical attention is more inclined to the improvement of pulse signal acquisition instruments and methods, or to conduct in-depth analysis and research on a certain link of pulse signal processing and analysis, lacking certain coherence and systematic pulse detection and analysis methods, or It is because some factors that will affect the pulse detection are not properly dealt with, such as light. Therefore, it is extremely necessary to propose a complete, systematic and rigorous pulse condition analysis method.
发明内容Contents of the invention
鉴于上述现有技术存在的不足,本发明目的是提供一种基于PPG信号和图像增强的脉象分析方法,消除光照因素对脉象检测的影响,实现稳定的、客观化的脉象诊断。In view of the deficiencies in the above-mentioned prior art, the purpose of the present invention is to provide a pulse condition analysis method based on PPG signal and image enhancement, eliminate the influence of illumination factors on pulse condition detection, and realize stable and objective pulse condition diagnosis.
为了实现上述目的,本发明提出的基于PPG信号和图像增强的脉象分析方法,包括以下步骤:In order to achieve the above object, the pulse condition analysis method based on PPG signal and image enhancement proposed by the present invention may further comprise the steps:
第一步骤:通过普通计算机摄像头采集人脸视频图像;The first step: collect face video images through ordinary computer cameras;
第二步骤:通过改进的图像增强算法对视频图像进行增强处理;The second step: the video image is enhanced through an improved image enhancement algorithm;
第三步骤:将增强后的视频图像的RGB通道分离;The third step: separating the RGB channel of the enhanced video image;
第四步骤:ICA算法处理,并与G通道信号进行相关性分析得到PPG脉搏波信号;The fourth step: ICA algorithm processing, and correlation analysis with the G channel signal to obtain the PPG pulse wave signal;
第五步骤:脉搏波信号去噪;The fifth step: pulse wave signal denoising;
第六步骤:求取PPG脉搏波信号的各特征点;The sixth step: obtaining each characteristic point of the PPG pulse wave signal;
第七步骤:将提取的脉搏波特征值输入KNN算法输出结果Step 7: Input the extracted pulse wave feature value into the KNN algorithm output result
第八步骤:脉象信号分类结果与标准数据库对比,判断病症。The eighth step: compare the results of pulse signal classification with the standard database to judge the disease.
进一步地,所述第一步骤中,所述的基于PPG信号和图像增强的脉象分析方法,其特征在于:所述第一步骤中,使用普通电脑的摄像头采集人脸视频图像,采集信号者需要静坐于电脑前,露出前额,停留一段时间,禁止较大的肢体动作,保持自然的面部表情。Further, in the first step, the described pulse condition analysis method based on PPG signal and image enhancement is characterized in that: in the first step, the camera of an ordinary computer is used to collect face video images, and the person who collects the signal needs to Sit quietly in front of the computer, with your forehead exposed, stay for a while, prohibit large body movements, and maintain a natural facial expression.
进一步地,所述第二步骤中,所述视频图像的增强方法的具体流程如下:Further, in the second step, the specific flow of the video image enhancement method is as follows:
步骤1:对图像的各通道进行修正的自动对比度拉伸;Step 1: Corrected automatic contrast stretching for each channel of the image;
步骤2:基于HSV的颜色空间的相互转换;Step 2: Mutual conversion of HSV-based color spaces;
步骤3:对V分量进行分段的线性变换。Step 3: Perform piecewise linear transformation on the V component.
进一步地,所述第二步骤中,所述修正的自动对比度拉伸公式为:Further, in the second step, the modified automatic contrast stretching formula is:
其中分别代表低照度图像的像素值的两个阈值,可以通过下式得到:in The two thresholds representing the pixel values of the low-illumination image respectively can be obtained by the following formula:
上式中:0≤tlow,thigh≤1,tlow+thigh≤1。In the above formula: 0≤t low , t high ≤1, t low +t high ≤1.
进一步地,所述第二步骤中,所述在HSV空间的V分量分段线性变换为:Further, in the second step, the piecewise linear transformation of the V component in the HSV space is:
对V分量的像素值按从小到大的顺序进行排序,得到排序后的向量记为V'=hM×N(x),设对V'进行分段处理的参数为n,分段的像素个数为对每个分段V'i设定一个像素的最小值和最大值对每一分段进行线性变换的表达式如下:线性变换后得到g(x)=[g0(x),g1(x),Λ gn(x)],重构g(x)为M×N维矩阵V”=|g(x,y)|,最后将图像从HSV空间转换到RGB空间得到增强后的视频图像。The pixel values of the V component are sorted in ascending order, and the sorted vector is denoted as V'=h M × N (x), and the parameter for segmenting V' is set to n, and the segmented pixels The number is Set a minimum value of one pixel for each segment V' i and the maximum The expression for linear transformation of each segment is as follows: After linear transformation, g(x)=[g 0 (x), g 1 (x), Λ g n (x)] is obtained, and g(x) is reconstructed into an M×N dimensional matrix V”=|g(x, y)|, and finally convert the image from HSV space to RGB space to obtain an enhanced video image.
进一步地,所述第四步骤中,所述ICA算法从人脸图像序列中提取出PPG脉搏波信号,把信号分离成统计独立的非高斯信号的信号源的线性组合,也就是从线性混合信号里恢复出基本的原信号Further, in the fourth step, the ICA algorithm extracts the PPG pulse wave signal from the face image sequence, and separates the signal into a linear combination of statistically independent non-Gaussian signal sources, that is, from the linear mixed signal recover the basic original signal
进一步地,所述第五步骤中,所述对脉搏波信号去噪是利用小波重构与经验模态分解(EMD)结合的方法。在小波变换进行分解后,将频带外的高频信号滤除,可有效滤除高频干扰,在利用小波变换方法对信号进行处理的过程中,选取Sym8小波函数作为小波基对阈值函数对信号进行分解,可以突出不同特点的信号特征。然后对小波分解后脉搏波信号频带内的小波系数,进一步做经验模态分解(EMD)方法的分解,得到新的小波系数。Further, in the fifth step, the denoising of the pulse wave signal is a method combining wavelet reconstruction and empirical mode decomposition (EMD). After the wavelet transform is decomposed, the high-frequency signal outside the frequency band is filtered out, which can effectively filter out the high-frequency interference. Decomposition can highlight signal features with different characteristics. Then, after wavelet decomposition, the wavelet coefficients in the pulse wave signal frequency band are further decomposed by the empirical mode decomposition (EMD) method to obtain new wavelet coefficients.
进一步地,所述第六步骤中,所述求PPG脉搏波信号的各特征点,包括脉搏波的力度,脉搏波上升的快慢,脉搏波下降的快慢,一个周期脉搏波的宽度,重博波的力度,一分钟内脉搏波的周期数。Further, in the sixth step, the feature points of the PPG pulse wave signal include the dynamics of the pulse wave, the speed of the pulse wave rise, the speed of the pulse wave fall, the width of a cycle pulse wave, the dicrotic wave The strength, the number of pulse wave cycles in one minute.
进一步地,所述第七步骤中,所述KNN算法对脉象信号进行识别分类中,是将PPG信号的各特征点作为输入,运用机器学习的KNN聚类算法对脉象信号进行预测分类。Further, in the seventh step, when the KNN algorithm recognizes and classifies the pulse signal, each feature point of the PPG signal is used as input, and the KNN clustering algorithm of machine learning is used to predict and classify the pulse signal.
进一步地,所述第八步骤中,所述判断病症中是将KNN算法的预测分类结果与标准数据库进行对比,判断脉象所代表的症状。Further, in the eighth step, in the judgment of the disease, the predicted classification result of the KNN algorithm is compared with the standard database to judge the symptom represented by the pulse condition.
本发明与现有脉象分析方法相比,具有如下优点:Compared with the existing pulse condition analysis method, the present invention has the following advantages:
1、提出了一种非接触式的脉象分析方法,操作简单,成本低。1. A non-contact pulse condition analysis method is proposed, which is easy to operate and low in cost.
2、提出的视频图像增强方法消除了光照不均的情况下对脉象分析的影响,保证了脉搏信息的稳定性。2. The video image enhancement method proposed eliminates the influence of uneven illumination on pulse analysis and ensures the stability of pulse information.
3、结合小波和EMD对脉搏波信号进行去噪,进一步提升了脉象分析结果。3. Combining wavelet and EMD to denoise the pulse wave signal, further improving the results of pulse condition analysis.
3、提出的根据PPG脉搏波特征点运用KNN算法对脉象进行识别分类易于理解,便于实现。3. According to the feature points of PPG pulse wave, the KNN algorithm is used to identify and classify the pulse condition, which is easy to understand and easy to implement.
4、提出的脉象分析方法将传统医学的理论同现代的计算机科学相结合,能够有效地实现稳定、严谨、客观化的脉象检测和诊断。4. The proposed pulse condition analysis method combines traditional medical theory with modern computer science, and can effectively realize stable, rigorous and objective pulse condition detection and diagnosis.
附图说明Description of drawings
为了更清楚地说明本发明实施例或现有技术中的技术方案,下面将对实施例或现有技术描述中所需要使用的附图作简单地介绍,显而易见地,下面描述中的附图仅仅是本发明的一些实施例,对于本领域普通技术人员来讲,在不付出创造性劳动性的前提下,还可以根据这些附图获得其他的附图:In order to more clearly illustrate the technical solutions in the embodiments of the present invention or the prior art, the following will briefly introduce the drawings that need to be used in the description of the embodiments or the prior art. Obviously, the accompanying drawings in the following description are only These are some embodiments of the present invention. For those of ordinary skill in the art, other drawings can also be obtained according to these drawings on the premise of not paying creative labor:
图1为PPG脉搏波信号特征图。Figure 1 is a characteristic diagram of the PPG pulse wave signal.
图2为本发明方法的流程图。Fig. 2 is a flow chart of the method of the present invention.
图3本发明提出的基于人脸视频图像增强方法实施示意图。Fig. 3 is a schematic diagram of implementation of the face-based video image enhancement method proposed by the present invention.
具体实施方式Detailed ways
下面结合附图对本发明作进一步的详细描述,但本发明的实施和保护范围不限于此。The present invention will be further described in detail below in conjunction with the accompanying drawings, but the implementation and protection scope of the present invention are not limited thereto.
光电容积脉搏波描记法(PPG)是一种利用活体组织对光吸收检测血液容积变化的一种无创检测方法。如图1所示,为PPG脉搏波信号特征图,横轴为时间,纵轴为血液容积的大小变化。U点,脉搏波信号的最低点,此时心脏进入收缩阶段,大量血液射入主动脉,人体血管中的血容积增加,是波形的最低点,即射血的开始。Z点,是信号的顶点,此时血管内血容积量达到最大值。W点,是信号降支中的局部顶点,对应于返流血液遇到已关闭的主动脉瓣反射后的最大射血量(部分个体拐点不明显或没有)。V点,心脏收缩期结束,代表射血结束。Photoplethysmography (PPG) is a non-invasive detection method that uses light absorption by living tissue to detect changes in blood volume. As shown in FIG. 1 , it is a characteristic map of the PPG pulse wave signal, the horizontal axis is time, and the vertical axis is the change of blood volume. Point U is the lowest point of the pulse wave signal. At this time, the heart enters the systolic stage, a large amount of blood is injected into the aorta, and the blood volume in the blood vessels of the human body increases. This is the lowest point of the waveform, that is, the beginning of blood ejection. Point Z is the apex of the signal, at which point the blood volume in the blood vessel reaches the maximum value. Point W is the local apex in the descending branch of the signal, corresponding to the maximum ejection volume after the regurgitated blood encounters the reflection of the closed aortic valve (the inflection point of some individuals is not obvious or absent). Point V, the end of systole, represents the end of ejection.
如图2所示,为本发明方法的流程图,通过普通计算机摄像头采集人脸视频图像,使用普通电脑的摄像头采集人脸视频图像,采集信号者需要静坐于电脑前,露出前额,停留约一分钟,禁止较大的肢体动作,保持自然的面部表情;通过改进的图像增强算法对视频图像进行增强处理,防止低光照问题对脉象检测分析的影响;然后将增强后的视频图像的RGB通道分离;随后,运用ICA算法处理,并将处理结果与G通道信号进行相关性分析得到PPG脉搏波信号;然后结合小波和EMD对获取到的PPG脉搏波信号进行去噪;随后求PPG脉搏波信号的各特征点;将提取的脉搏波特征值输入KNN算法输出结果;最后,将脉象信号分类结果与标准数据库对比,判断病症。As shown in Figure 2, it is a flow chart of the method of the present invention. The face video image is collected by an ordinary computer camera, and the face video image is collected by an ordinary computer camera. The person collecting the signal needs to sit quietly in front of the computer, expose the forehead, and stay for about Minutes, large body movements are prohibited, and natural facial expressions are maintained; video images are enhanced through an improved image enhancement algorithm to prevent low-light problems from affecting pulse detection and analysis; and then the RGB channels of the enhanced video images are separated ; Subsequently, use the ICA algorithm to process, and conduct correlation analysis between the processing results and the G channel signal to obtain the PPG pulse wave signal; then combine wavelet and EMD to denoise the obtained PPG pulse wave signal; then calculate the PPG pulse wave signal Each feature point; input the extracted pulse wave feature value into the KNN algorithm output result; finally, compare the pulse signal classification result with the standard database to judge the disease.
如图3所示,视频图像增强方法包括对图像的各通道进行修正的自动对比度拉伸;基于HSV的颜色空间的相互转换;对V分量进行分段的线性变换。As shown in Figure 3, the video image enhancement method includes automatic contrast stretching for correcting each channel of the image; mutual conversion of color spaces based on HSV; segmented linear transformation for V components.
对视频图像的各通道进行修正的自动对比度拉伸公式为:The formula for automatic contrast stretching that corrects each channel of a video image is:
其中分别代表低照度图像的像素值的两个阈值,可以通过下式得到:in The two thresholds representing the pixel values of the low-illumination image respectively can be obtained by the following formula:
通过公式可以将像素值小于等于大于等于的值分别映射到xmin与xmax,其它的值则被映射到xmin、xmax之间。The pixel value can be less than or equal to the formula greater or equal to The values of are mapped to x min and x max respectively, and other values are mapped to between x min and x max .
在HSV空间的V分量分段线性变换为:The piecewise linear transformation of the V component in HSV space is:
对V分量的像素值按从小到大的顺序进行排序,得到排序后的向量记为V'=hM×N(x),设对V'进行分段处理的参数为n,分段的像素个数为对每个分段V'i设定一个像素的最小值和最大值对每一分段进行线性变换的表达式为线性变换后得到g(x)=[g0(x),g1(x),L gn(x)],重构g(x)为M×N维矩阵V”=|g(x,y)|,最后将图像从HSV空间转换到RGB空间得到增强后的视频图像;The pixel values of the V component are sorted in ascending order, and the sorted vector is denoted as V'=h M × N (x), and the parameter for segmenting V' is set to n, and the segmented pixels The number is Set a minimum value of one pixel for each segment V' i and the maximum The expression for linear transformation of each segment is After linear transformation, g(x)=[g 0 (x), g 1 (x), L g n (x)], reconstruct g(x) into M×N dimensional matrix V”=|g(x, y)|, and finally convert the image from HSV space to RGB space to obtain an enhanced video image;
ICA算法是把信号分离成统计独立的非高斯信号的信号源的线性组合,也就是从线性混合信号里恢复出基本的原信号。对PPG脉搏波信号进行滤波预处理是选取合适的阈值H及设定特殊的规则过滤掉干扰点。为了消除比较大的干扰的影响,对样本点进行分段处理,求出每个段的最大值,然后求这些最大值的平均值,最后设定一定的比例作为阈值;PPG脉搏波信号的各特征点,包括脉搏波的力度,脉搏波上升的快慢,脉搏波下降的快慢,一个周期脉搏波的宽度,重博波的力度,一分钟内脉搏波的周期数等。运用机器学习的聚类算法对脉象信号进行预测分类;预测分类结果与标准数据库对比,并判断脉象所代表的症状。The ICA algorithm is a linear combination of signal sources that separates the signal into statistically independent non-Gaussian signals, that is, recovers the basic original signal from the linear mixed signal. The filter preprocessing of PPG pulse wave signal is to select the appropriate threshold H and set special rules to filter out the interference points. In order to eliminate the influence of relatively large interference, the sample points are segmented, and the maximum value of each segment is calculated, and then the average value of these maximum values is calculated, and finally a certain ratio is set as the threshold value; each of the PPG pulse wave signal The characteristic points include the strength of the pulse wave, the speed of the pulse wave rising, the speed of the pulse wave falling, the width of a cycle pulse wave, the strength of the pulse wave, the number of cycles of the pulse wave in one minute, etc. The clustering algorithm of machine learning is used to predict and classify the pulse signal; the predicted classification results are compared with the standard database, and the symptoms represented by the pulse are judged.
上述实施例为本发明较佳的实施方式,但本发明的实施方式并不受上述实施例的限制,其他的任何未背离本发明的精神实质与原理下所作的改变、修饰、替代、组合、简化,均应为等效的置换方式,都包含在本发明的保护范围之内。The above-mentioned embodiment is a preferred embodiment of the present invention, but the embodiment of the present invention is not limited by the above-mentioned embodiment, and any other changes, modifications, substitutions, combinations, Simplifications should be equivalent replacement methods, and all are included in the protection scope of the present invention.
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