CN108324275A - A kind of acquisition method and device of magnetic resonance imaging signal and spectroscopic signal - Google Patents
A kind of acquisition method and device of magnetic resonance imaging signal and spectroscopic signal Download PDFInfo
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- CN108324275A CN108324275A CN201810004859.8A CN201810004859A CN108324275A CN 108324275 A CN108324275 A CN 108324275A CN 201810004859 A CN201810004859 A CN 201810004859A CN 108324275 A CN108324275 A CN 108324275A
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Abstract
The embodiment of the present application discloses a kind of acquisition method and device of magnetic resonance imaging signal and spectroscopic signal.This method encourages the effective time gap between acquisition using magnetic resonant wave spectrum signal, after the plane interested excitation of magnetic resonance imaging object, before acquisition magnetic resonant wave spectrum signal, acquire magnetic resonance imaging signal, so, magnetic resonance imaging signal and magnetic resonant wave spectrum signal can be obtained in a Magnetic Resonance Spectrum signal scanning sequence, so, acquisition method provided by the embodiments of the present application can obtain magnetic resonance imaging signal and magnetic resonant wave spectrum signal in a Magnetic Resonance Spectrum scanning sequence, therefore, magnetic resonance imaging signal gatherer process and Magnetic Resonance Spectrum signal acquisition process are integrated into a signal acquisition sequence by acquisition method provided by the embodiments of the present application.Thus, compared to the prior art, the time that acquisition method provided by the embodiments of the present application saves acquisition magnetic resonance imaging signal improves scan efficiency to save the magnetic resonance imaging time.
Description
Technical field
This application involves magnetic resonance arts more particularly to a kind of acquisition sides of magnetic resonance imaging signal and spectroscopic signal
Method and device.
Background technology
Magnetic resonance imaging (Magnetic Resonance Imaging, MRI) as a kind of multi-parameter, more contrasts at
As technology, it is one of main imaging mode in modern medical service iconography, can reflects that tissue T 1, T2 and proton density etc. are more
Kind characteristic, can provide information for the detection and diagnosis of disease.The basic functional principle of magnetic resonance imaging is to utilize electromagnetic induction phenomenon,
It is position encoded with gradient fields progress using the Hydrogen Proton in RF excited exciting human, band is then received using receiving coil
The electromagnetic signal of location information finally reconstructs image information using Fourier transformation.
Magnetic resonance spectroscopy (Magnetic Resonance Spectroscopy, MRS) is to utilize the change in magnetic resonance
Displacement study measures a kind of detection method of molecular composition and steric configuration.MRS be it is currently the only being capable of Non-invasive detection live body group
Knit interior chemical substance, response organization's cell metabolism, the method for expressing pathological change.
It is further stringent to magnetic resonance imaging time requirement in Present clinical, how within limited sweep time to collect magnetic
Resonance image-forming signal and spectroscopic signal are most important to the development of magnetic resonance clinical diagnosis.
Invention content
In view of this, the embodiment of the present application provides a kind of acquisition method and dress of magnetic resonance imaging signal and spectroscopic signal
It sets, magnetic resonance imaging signal gatherer process and Magnetic Resonance Spectrum signal acquisition process is integrated into a signal acquisition sequence,
To achieve the purpose that save the magnetic resonance imaging time and improve scan efficiency.
In order to reach foregoing invention purpose, the embodiment of the present application uses following technical solution：
A kind of acquisition method of magnetic resonance imaging signal and spectroscopic signal, is wrapped in a magnetic resonance signal scanning sequence
It includes：
The plane interested of magnetic resonance imaging object is excited using driving pulse；
Acquire magnetic resonance imaging signal；
After two 180 ° times poly- pulses perpendicular to excitation plane, the Magnetic Resonance Spectrum letter that there is water signal to inhibit is acquired
Number.
Optionally, before the acquisition magnetic resonance imaging signal, further include：It is inserted into for generating different contrast image
It is imaged pre-preparation pulse.
Optionally, imaging pre-preparation pulse of the insertion for generating different contrast image, specifically includes：
Before the plane interested for exciting magnetic resonance imaging object using driving pulse, it is inserted on excitation plane
The inversion pulse subsequence of the arterial blood label of trip.
Optionally, imaging pre-preparation pulse of the insertion for generating different contrast image, specifically includes：
It is inserted between the plane interested and acquisition magnetic resonance imaging signal of excitation magnetic resonance imaging object and is used for disperse
The bipolar pulse gradient of weighted imaging.
Optionally, before the plane interested for exciting magnetic resonance imaging object using driving pulse, further include：
It is inserted into the pre-preparation pulse inhibited for water signal.
Optionally, after acquiring magnetic resonance imaging signal, acquire have water signal inhibit magnetic resonant wave spectrum signal it
Before, further include：
The pulse be inserted into after poly- pulse and inhibited for water signal is returned at each described 180 °.
A kind of harvester of magnetic resonance imaging signal and spectroscopic signal, including：
Module is encouraged, for the plane interested using driving pulse excitation magnetic resonance imaging object；
Image acquisitions module, for acquiring magnetic resonance imaging signal；
Spectroscopic signal acquisition module, for after two 180 ° times poly- pulses perpendicular to excitation plane, acquisition to have water
The magnetic resonant wave spectrum signal that signal inhibits.
Optionally, described device further includes：
Be imaged pre-preparation module, for before acquire magnetic resonance imaging signal be used for generate different contrast image at
As pre-preparation pulse.
Optionally, the imaging pre-preparation module is specially：It is flat to exciting for before exciting plane interested, executing
The inversion pulse subsequence of the arterial blood label of face upstream.
Optionally, the imaging pre-preparation module is specially：For exciting plane interested and acquisition magnetic resonance imaging
Between signal, the bipolar pulse gradient for diffusion-weighted imaging is executed.
Compared to the prior art, the embodiment of the present application has the advantages that：
In Magnetic Resonance Spectrum signal scanning sequence, one section of duration can be undergone from signal excitation to signal acquisition, be based on this,
Acquisition method provided by the embodiments of the present application, the effective time gap between encouraging and acquire using magnetic resonant wave spectrum signal,
After the plane interested excitation of magnetic resonance imaging object, before acquiring magnetic resonant wave spectrum signal, magnetic resonance imaging signal is acquired, such as
This, as soon as magnetic resonance imaging signal and magnetic resonant wave spectrum signal can be obtained in Magnetic Resonance Spectrum signal scanning sequence,
It is to say, the gatherer process of magnetic resonance imaging signal is integrated into Magnetic Resonance Spectrum signal scanning sequence by the embodiment of the present application, such as
This, acquisition method provided by the embodiments of the present application can obtain magnetic resonance imaging signal in a Magnetic Resonance Spectrum scanning sequence
With magnetic resonant wave spectrum signal, therefore, acquisition method provided by the embodiments of the present application is by magnetic resonance imaging signal gatherer process and magnetic
Resonance spectroscopic signal gatherer process is integrated into a signal acquisition sequence.Thus, compared to the prior art, the embodiment of the present application carries
The time that the acquisition method of confession saves acquisition magnetic resonance imaging signal improves and sweeps to save the magnetic resonance imaging time
Retouch efficiency.
Description of the drawings
In order to which the specific implementation mode of the application is expressly understood, used when the application specific implementation mode is described below
Attached drawing do a brief description.It should be evident that these attached drawings are only the section Examples of the application.
Fig. 1 is the magnetic resonance system schematic diagram that the embodiment of the present application uses；
Fig. 2 is Gradient echoes sequence schematic diagram；
Fig. 3 is magnetic resonance monomer vegetarian refreshments discerning method wave spectrum schematic diagram；
Fig. 4 is the magnetic resonance signal scanning sequence schematic diagram of conventional Magnetic Resonance Spectrum monomer vegetarian refreshments discerning method；
Fig. 5 is the specific example signal of the magnetic resonance signal scanning sequence based on Magnetic Resonance Spectrum monomer vegetarian refreshments discerning method
Figure；
Fig. 6 is a specific example stream of magnetic resonance imaging signal provided by the embodiments of the present application and spectroscopic signal acquisition method
Journey schematic diagram；
Fig. 7 is that another specific example of the magnetic resonance signal scanning sequence based on Magnetic Resonance Spectrum monomer vegetarian refreshments discerning method is shown
It is intended to；
Fig. 8 is magnetic resonance imaging signal provided by the embodiments of the present application and another specific example of spectroscopic signal acquisition method
Flow diagram；
Fig. 9 is that the another specific example of the magnetic resonance signal scanning sequence based on Magnetic Resonance Spectrum monomer vegetarian refreshments discerning method is shown
It is intended to；
Figure 10 is the another specific example of the magnetic resonance signal scanning sequence based on Magnetic Resonance Spectrum monomer vegetarian refreshments discerning method
Schematic diagram；
Figure 11 is that the control device for the acquisition method that the embodiment of the present application executes magnetic resonance imaging signal and spectroscopic signal shows
It is intended to；
Figure 12 is the harvester structural schematic diagram of magnetic resonance imaging signal provided by the embodiments of the present application and spectroscopic signal.
Specific implementation mode
Currently, magnetic resonance imaging signal gatherer process and Magnetic Resonance Spectrum signal acquisition process are two completely self-contained letters
Number gatherer process.In this way, the magnetic resonance imaging time is the sum of magnetic resonance imaging signal sweep time and spectroscopic signal sweep time,
Cause the acquisition of magnetic resonance signals time longer, causes magnetic resonance imaging less efficient.
In addition, because magnetic resonance imaging signal gatherer process and Magnetic Resonance Spectrum signal acquisition process are completely independent, cause into
As existence time is poor between the acquisition time of signal and the acquisition time of spectroscopic signal, thus lead to the imaging signal and wave of acquisition
Spectrum signal relative discrete, and if scanning in interval time of the magnetic resonance imaging signal with scanning magnetic resonant wave spectrum signal, disease
People moves, and may result in collected magnetic resonance imaging signal and magnetic resonant wave spectrum signal may not be from the same body of patient
The signal in region, in this way, causing magnetic resonance imaging that cannot be registrated completely with wave spectrum, to make troubles to clinical diagnosis.
Present inventor is made that following research is found during solving above-mentioned technical problem：In magnetic resonant wave
It is not to acquire spectroscopic signal at once, but adopted from signal excitation to spectroscopic signal in spectrum signal scanning sequence, after signal excitation
Rally one section of duration of experience.And the acquisition of magnetic resonance imaging signal is to acquire immediately after excitation, and acquire magnetic resonance imaging letter
Number and acquisition Magnetic Resonance Spectrum signal process driving pulse can share.It is found based on the studies above, the embodiment of the present application profit
Effective time gap between being encouraged and acquired with magnetic resonant wave spectrum signal is excited in the plane interested of magnetic resonance imaging object
Afterwards, before acquiring magnetic resonant wave spectrum signal, magnetic resonance imaging signal is acquired, in this way, in a Magnetic Resonance Spectrum signal scanning sequence
Magnetic resonance imaging signal and magnetic resonant wave spectrum signal can be obtained in row, that is to say, that the embodiment of the present application is by magnetic resonance imaging
The gatherer process of signal is integrated into Magnetic Resonance Spectrum signal scanning sequence, in this way, magnetic resonance provided by the embodiments of the present application at
As the acquisition method of signal and spectroscopic signal can be obtained in a Magnetic Resonance Spectrum scanning sequence magnetic resonance imaging signal and
Magnetic resonance imaging signal gatherer process and magnetic are total to by magnetic resonant wave spectrum signal, therefore, acquisition method provided by the embodiments of the present application
Vibration wave spectrum signal gatherer process is integrated into a signal acquisition sequence.Thus, compared to the prior art, the embodiment of the present application provides
Acquisition method save acquisition magnetic resonance imaging signal time improve scanning to save the magnetic resonance imaging time
Efficiency.
Moreover, the collected magnetic resonance imaging signal of the embodiment of the present application and magnetic resonant wave spectrum signal are after primary excitation
Collected signal, it can be ensured that the collected signal of two kinds of signals from the same body part of patient, therefore, it is possible to true
It protects magnetic resonance imaging to be registrated with the complete of Magnetic Resonance Spectrum, so as to ensure accurately clinical diagnosis.
The specific implementation mode of the application is described in detail below in conjunction with the accompanying drawings.
Fig. 1 is combined to introduce the magnetic resonance system 10 of the embodiment of the present application use first.Referring to Fig. 1, the magnetic resonance system packet
Include magnetic resonance scanner 11, console 12, peripheral equipment 13, MRI processing modules 14 and MRS processing modules 15.
Wherein, the internal components of magnetic resonance scanner 11 for example including：Generate the superconduction type or resistor-type of magnetostatic field (B0)
Magnet 111, more set magnetic field gradient coils windings 112 for being superimposed upon selected magnetic field gradient on magnetostatic field, for generating
The radio-frequency sending coil 113 of radiofrequency field (B1), the RF receiving coil for detecting the magnetic resonance signal emitted from sweep object
114 and the sick bed 115 for accommodating sweep object.
Console 12 sends out magnetic resonance imaging control instruction for operating personnel, and can show the magnetic resonance ultimately generated
Imaging and Magnetic Resonance Spectrum.
Peripheral equipment 13 includes gradient power amplifier 131, RF power amplification 132, receiving unit 133, door control unit 134, radio frequency control
Unit 135, gradient control unit 136, sickbed control unit 137 and sequence control unit 138 processed etc..
MRI processing modules 14 are used for after receiving MRI signal from receiving unit 133, are carried out at image to the MRI signal
Reason, such as Fourier transformation generate MR images.
MRS processing modules 15 are used for after receiving MRS signals from receiving unit 133, are carried out at image to the MRS signals
Reason, such as Fourier transformation generate MR wave spectrums.
The acquisition method of magnetic resonance imaging signal provided by the embodiments of the present application and spectroscopic signal only relates to shown in Fig. 1
Magnetic resonance scanner 11, console 12, peripheral equipment 13 are included in magnetic resonance system 10, is not related to the MRI for image procossing
Processing module 14 and the MRS processing modules 15 handled for wave spectrum.
Below using gtadient echo planar imaging as the example of magnetic resonance imaging, using monomer vegetarian refreshments discerning method as magnetic resonance
The example of wave spectrum acquisition describes the specific implementation mode of the application.
Wherein, voxel is the space cell in magnetic resonance imaging or wave spectrum acquisition.
Gtadient echo planar imaging (Echo Planar Imaging, EPI) is current widely used fast imaging sequence
Row generate a series of gtadient echos using snap back gradient and distinguish phase code to it, fill after a radio-frequency drive
Imaging is realized by Fourier transformation to corresponding k-space.Fig. 2 shows Gradient echoes sequence schematic diagrames, also referred to as terraced
Echo pulse sequence sequence diagram is spent, which show the time serieses of the application of various pulses.For example, the line labeled as RF indicates RF
Pulse, the RF pulses in Fig. 2 are 90 ° of pulses.The gradient applied along the direction x, y and z is indicated respectively labeled as the line of Gx, Gy and Gz
Pulse.
Monomer vegetarian refreshments discerning method can be adopted after two time poly- pulses perpendicular to excitation plane after a radio-frequency drive
Collection, is limited to spectroscopic signal the vertical junction of three pulses (excitation pulse and two orthogonal go back to poly- pulses), i.e.,
A focal area interested in plane, obtains the signal in the region, is obtained in rectangular co-ordinate not by Fourier transform
Curve, that is, magnetic resonance spectroscope of frequency distribution is pressed with chemical substance peak.The corresponding magnetic resonance spectroscope is as shown in Figure 3.
The magnetic resonance signal scanning sequence of conventional Magnetic Resonance Spectrum monomer vegetarian refreshments discerning method is as shown in Figure 4.It includes：Swash
It encourages 41, the 1st ° of pulse and returns 42, the 2nd 180 ° times poly- pulses 43 of poly- pulse and Magnetic Resonance Spectrum acquisition subsequence 44.
Because in vivo about 78% is water, in order to inhibit influence of the strong water peak signal to wave spectrum, in sequence shown in Fig. 4
It can also include the pre-preparation pulse inhibited for water signal before being inserted in Magnetic Resonance Spectrum acquisition subsequence 44.According to
In the type for the pre-preparation pulse 45 that water signal inhibits, which is inserted into excitation arteries and veins
Before punching 41, it can also be inserted in after driving pulse 41.
Wherein, the pre-preparation pulse inhibited for water signal before being inserted in driving pulse 41 can be that wet method presses water vein
Punching 45.
It can be specially that be inserted into respectively to be inserted in the pre-preparation pulse 45 inhibited for water signal after driving pulse 41
The MEGA that after poly- pulse 42 and the 2nd 180 ° is returned after poly- pulse 43 is returned at the one 180 °, and (full name is that selective echo dissipates
Phase method) pressure aquapulse 451 and 452.
In order to reduce the magnetic resonance imaging time, sweep speed, magnetic resonance imaging signal provided by the present application and wave spectrum are improved
The gatherer process of signal is integrated into Magnetic Resonance Spectrum signal acquisition sequence.In other words, the embodiment of the present application by magnetic resonance at
As acquisition subsequence is inserted into Magnetic Resonance Spectrum signal acquisition sequence.As the specific example of the application, Fig. 5 shows base
In a specific example schematic diagram of the magnetic resonance signal scanning sequence of Magnetic Resonance Spectrum monomer vegetarian refreshments discerning method.It should be in specific example
Shown in magnetic resonance signal scanning sequence include：The wet method inhibited for water signal presses aquapulse 45, driving pulse 41, magnetic total
51, the 1st ° of the imaging acquisition subsequence that shakes returns 42, the 2nd 180 ° of poly- pulse and returns poly- pulse 43 and Magnetic Resonance Spectrum acquisition
Sequence 44.As can be seen that magnetic resonance imaging acquisition subsequence 51 is inserted by the application example from acquisition sequence shown in fig. 5
To the driving pulse 41 in Magnetic Resonance Spectrum acquisition sequence shown in Fig. 4 and between the one 180 ° time poly- pulse 42.
In the specific example, as shown in fig. 6, in a magnetic resonance signal scanning sequence, magnetic resonance imaging signal and
The acquisition method of spectroscopic signal includes the following steps：
S61：Aquapulse 45 is pressed using the wet method inhibited for water signal.
In the living body, the concentration of metabolin is a ten thousandth of water concentration, and the effect that water inhibits makes from metabolin
Small signal can be detected.
It, can be in excitation magnetic resonance imaging pair in order to inhibit influence of the strong water peak signal to wave spectrum in the application example
Before the plane interested of elephant, aquapulse 45 is pressed using the wet method inhibited for water signal.Wet method presses aquapulse 45 by multiple
The soft pulse continuous action of different flip angles reaches effective inhibition to water peak.Under normal circumstances, wet method pressure aquapulse addition
Before exciting plane interested.
S62：The plane interested of magnetic resonance imaging object is excited using driving pulse 41.
As an example, 90 ° of RF pulses may be used as driving pulse 41, to excite the interested of magnetic resonance imaging object
Plane.
S63：It executes magnetic resonance imaging acquisition subsequence 51 and acquires magnetic resonance imaging signal.
After plane interested is excited, it is immediately performed magnetic resonance imaging acquisition subsequence 51 and acquires magnetic resonance imaging letter
Number.
S64：It executes the one 180 ° time poly- pulse 42 perpendicular to excitation plane and the 2nd 180 ° is returned poly- pulse 43.
180 ° are returned poly- pulse and are used to make the proton of the dephasing in x/y plane to invert 180 ° and again rephasing.
S65：After having executed the 180 ° times poly- pulses 42 and 43 perpendicular to excitation plane, Magnetic Resonance Spectrum acquisition is executed
The acquisition of sequence 44 has the magnetic resonant wave spectrum signal that water signal inhibits.
In the embodiment of the present application, the plane interested of excitation plane and the magnetic resonance imaging object of excitation is same flat
Face.
It is an example of the acquisition method of magnetic resonance imaging signal provided by the embodiments of the present application and spectroscopic signal above
Specific implementation.In the specific implementation, the effective time between encouraging and acquire using magnetic resonant wave spectrum signal
Gap before acquiring magnetic resonant wave spectrum signal, acquires magnetic resonance imaging after the plane interested excitation of magnetic resonance imaging object
Signal, in this way, magnetic resonance imaging signal and Magnetic Resonance Spectrum letter can be obtained in a Magnetic Resonance Spectrum signal scanning sequence
Number, that is to say, that the gatherer process of magnetic resonance imaging signal is integrated into Magnetic Resonance Spectrum signal scanning sequence by the embodiment of the present application
In row, in this way, acquisition method provided by the embodiments of the present application can obtain magnetic resonance in a Magnetic Resonance Spectrum scanning sequence
Imaging signal and magnetic resonant wave spectrum signal, therefore, acquisition method provided by the embodiments of the present application acquires magnetic resonance imaging signal
Process and Magnetic Resonance Spectrum signal acquisition process are integrated into a signal acquisition sequence.Thus, compared to the prior art, the application
The acquisition method that embodiment provides saves the time of acquisition magnetic resonance imaging signal, to save the magnetic resonance imaging time,
Improve scan efficiency.
Moreover, the collected magnetic resonance imaging signal of the embodiment of the present application and magnetic resonant wave spectrum signal are after primary excitation
Collected signal, it can be ensured that the collected signal of two kinds of signals from the same body part of patient, therefore, it is possible to true
It protects magnetic resonance imaging to be registrated with the complete of Magnetic Resonance Spectrum, so as to ensure accurately clinical diagnosis.
It is to be appreciated that in the above-mentioned example, the pre-preparation pulse inhibited for water signal is adopted in magnetic resonance imaging signal
It is applied before collection, in fact, according to the scanning requirement for generating different contrast image, this is used for the pre-preparation arteries and veins of water signal inhibition
Punching can also reapply after magnetic resonance imaging signal acquires.Referring specifically to following example.
Fig. 7 shows another specific example of the magnetic resonance signal scanning sequence based on Magnetic Resonance Spectrum monomer element discerning method
Schematic diagram.Magnetic resonance signal scanning sequence includes shown in the specific example：
Driving pulse 41,71, the 1st ° of magnetic resonance imaging acquisition subsequence return poly- pulse 42, for water signal inhibition
The 2nd MEGA pulses 452 and magnetic resonance that first 451, the 2nd 180 ° of MEGA pulses are returned poly- pulse 43, inhibited for water signal
Wave spectrum acquires subsequence 44.As can be seen that magnetic resonance imaging acquisition subsequence 71 is inserted by the application example from the sequence
Between driving pulse 41 and the one 180 ° time poly- pulse 42 in Magnetic Resonance Spectrum acquisition sequence shown in Fig. 4.
In the specific example, as shown in figure 8, in a magnetic resonance signal scanning sequence, magnetic resonance imaging signal and
The acquisition method of spectroscopic signal includes the following steps：
S81：The plane interested of magnetic resonance imaging object is excited using driving pulse 41.
S82：It executes magnetic resonance imaging acquisition subsequence 71 and acquires magnetic resonance imaging signal.
S83：It executes the one 180 ° and returns poly- pulse 42.
S84：Using the first MEGA pulses 451 inhibited for water signal.
S85：It executes the 2nd 180 ° and returns poly- pulse 43.
S86：Using the 2nd MEGA pulses 452 inhibited for water signal.
S87：Execute the magnetic resonant wave spectrum signal that there is water signal to inhibit for the Magnetic Resonance Spectrum acquisition acquisition of subsequence 44.
It is to be appreciated that by two examples above, can simultaneously be got in a magnetic resonance imaging sequence can be anti-
It reflects the magnetic resonance imaging signal of anatomical structure information and can reflect the spectroscopic signal of tissue metabolism's function.
In addition, in order to get the image-forming information in addition to anatomical structure in a magnetic resonance imaging sequence, such as
Weighted information is perfused in Hemodynamics, can also be inserted into the sequence shown in above-mentioned example for generating different contrast image
Imaging pre-preparation pulse.Specifically, which can be inserted into before magnetic resonance imaging acquisition subsequence.
As an example, Fig. 9 is shown can get arterial spin labeling imaging letter in a magnetic resonance imaging sequence
The scanning sequence schematic diagram of breath and spectral information.As shown in figure 9, the scanning that the corresponding scanning sequence of the example is shown in Fig. 7
It can also include the inversion pulse subsequence 91 of the arterial blood label before being inserted into driving pulse 41 in sequence basis.It is specific
Including：The inversion pulse subsequence 91 of arterial blood label, driving pulse 41, magnetic resonance imaging acquire 71, the 1st ° of subsequence
It returns poly- pulse 42, inhibit for 451, the 2nd 180 ° times poly- pulses 43 of the first MEGA pulses of water signal inhibition, for water signal
The first MEGA pulses 452 and Magnetic Resonance Spectrum acquire subsequence 44.
It is to be appreciated that in the application example, the inversion pulse subsequence 91 of arterial blood label includes arterial blood label
Inversion pulse and delay time.
In this example, in order to not influence Perfusion weighted imaging, the water suppressor pulse for wave spectrum acquisition must be positioned at magnetic
After resonance image-forming subsequence 71.
Based on scanning sequence shown in Fig. 9, the acquisition method of magnetic resonance imaging signal and spectroscopic signal with based on shown in Fig. 7
The acquisition method of scanning sequence compare, can also include the following steps before step S81：
Execute the inversion pulse subsequence 91 of arterial blood label.
In this example, the inversion pulse subsequence marked by being inserted into arterial blood in acquisition of magnetic resonance signals sequence
91, Hemodynamics perfusion weighted information and physiological metabolism information can be got simultaneously in an acquisition sequence.In addition,
The characteristic of multiple averaging is all had using arterial spin labeling imaging and wave spectrum acquisition.
In addition, in this example, in order to not influence Perfusion weighted imaging, the water suppressor pulse for wave spectrum acquisition must position
After magnetic resonance imaging acquires subsequence.
In addition, in order to get diffusion-weighted imaging, it can be can also be wrapped on the basis of scanning sequence shown in Fig. 7
It includes：The bipolar pulse gradient for diffusion-weighted imaging being inserted between driving pulse and magnetic resonance imaging acquisition subsequence.
The corresponding sequence diagram of the example is as shown in Figure 10.It is specifically included：
Driving pulse 41, bipolar pulse gradient 101, magnetic resonance imaging 71, the 1st ° of subsequence of acquisition return poly- pulse 42,
451, the 2nd 180 ° of the 2nd MEGA arteries and veins for returning poly- pulse 43, inhibiting for water signal of the first MEGA pulses inhibited for water signal
Punching 452 and Magnetic Resonance Spectrum acquire subsequence 44.
Acquisition based on magnetic resonance imaging signal and spectroscopic signal that scanning sequence shown in Fig. 10, the application example provide
Method, can also be including following before step S81 and S82 compared with the acquisition method based on scanning sequence shown in Fig. 7
Step：
Bipolar pulse gradient 101 is executed, to prepare for diffusion-weighted imaging.
It is the specific implementation of the acquisition method of magnetic resonance imaging signal provided by the embodiments of the present application and spectroscopic signal above
Mode, in this specific embodiment, the gap before the wave spectrum in Magnetic Resonance Spectrum scanning sequence can be made full use of to acquire,
Magnetic resonance imaging acquisition sequence is inserted into the gap, which can be any fast imaging sequences,
In this way, in one sequence, magnetic resonance imaging information and the reflection life of reflection anatomical structure information can be got simultaneously
Manage the several types of contrast information such as the spectral information of metabolism.On the other hand, in order to get in addition to reflecting anatomical structure information
Other magnetic resonance imaging information, can also be inserted into acquisition of magnetic resonance signals sequence provided by the embodiments of the present application for giving birth to
At the pre-preparation pulse of different contrast image, by the element to magnetic resonance imaging sequence adjust slightly can by removed
Reflect the perfusion weighted information such as other magnetic resonance imaging information such as Hemodynamics other than anatomical structure information or disperse
Weighted information.
The magnetic resonance imaging signal of above-described embodiment and the acquisition method of spectroscopic signal can be as shown in Figure 11 control set
It is standby to execute.Control device shown in Figure 11 includes processor (processor1110, communication interface (Communications
Interface) 1120, memory (memory) 1130, bus 1140.Processor 1110, communication interface 1120, memory 1130
Mutual communication is completed by bus 1140.
Wherein, the logical order of the acquisition of magnetic resonance imaging signal and spectroscopic signal can be stored in memory 1130,
The memory for example can be nonvolatile memory (non-volatile memory).Processor 1110 can call execution
The logical order of the acquisition of magnetic resonance imaging signal and spectroscopic signal in memory 1130, to execute above-mentioned magnetic resonance imaging
The acquisition method of signal and spectroscopic signal.Logic as embodiment, the acquisition of the magnetic resonance imaging signal and spectroscopic signal refers to
Enable can the corresponding program of software in order to control, when processor executes the instruction, control device can be accordingly in display interface
The corresponding function interface of upper display instruction.
If the function of the logical order of the acquisition of magnetic resonance imaging signal and spectroscopic signal is with the shape of SFU software functional unit
Formula is realized and when sold or used as an independent product, can be stored in a computer read/write memory medium.It is based on
Such understanding, the technical solution of the disclosure substantially the part that contributes to existing technology or the technical solution in other words
Part can be expressed in the form of software products, which is stored in a storage medium, including
Some instructions are used so that a computer equipment (can be personal computer, server or the network equipment etc.) executes sheet
Invent all or part of step of each embodiment method.And storage medium above-mentioned includes：USB flash disk, mobile hard disk, read-only storage
Device (ROM, Read-Only Memory), random access memory (RAM, RandomAccess Memory), magnetic disc or light
The various media that can store program code such as disk.
The logical order of the acquisition of above-mentioned magnetic resonance imaging signal and spectroscopic signal is properly termed as " magnetic resonance imaging letter
Number and spectroscopic signal harvester ", which can be divided into each function module.Referring specifically to following embodiment.
The specific reality of the harvester of magnetic resonance imaging signal provided by the embodiments of the present application and spectroscopic signal is described below
Apply mode.
Figure 12 is the harvester structural schematic diagram of magnetic resonance imaging signal and spectroscopic signal.As shown in figure 12, the device
Including：
Module 121 is encouraged, for the plane interested using driving pulse excitation magnetic resonance imaging object；
Image acquisitions module 122, for acquiring magnetic resonance imaging signal；
Spectroscopic signal acquisition module 123, for after two 180 ° times poly- pulses perpendicular to excitation plane, acquisition to have
The magnetic resonant wave spectrum signal that water signal inhibits.
In order to get the image-forming information in addition to anatomical structure, above-mentioned institute in a magnetic resonance imaging sequence
The device stated can also include：
It is imaged pre-preparation module 120, for being used to generate different contrast image before acquiring magnetic resonance imaging signal
Imaging pre-preparation pulse.
Weighted information is perfused in order to get Hemodynamics, the imaging pre-preparation module 124 can be specially：
For before exciting plane interested, executing the inversion pulse subsequence to the arterial blood label of excitation plane upstream.
In order to diffusion-weighted information, the imaging pre-preparation module 124 can be specially：For interested in excitation
Between plane and acquisition magnetic resonance imaging signal, the bipolar pulse gradient for diffusion-weighted imaging is executed.
It is the specific implementation mode of the application above.
Claims (10)
1. the acquisition method of a kind of magnetic resonance imaging signal and spectroscopic signal, which is characterized in that scanned in a magnetic resonance signal
Sequence includes：
The plane interested of magnetic resonance imaging object is excited using driving pulse；
Acquire magnetic resonance imaging signal；
After two 180 ° times poly- pulses perpendicular to excitation plane, the magnetic resonant wave spectrum signal that there is water signal to inhibit is acquired.
2. according to the method described in claim 1, it is characterized in that, before the acquisition magnetic resonance imaging signal, further include：It inserts
Enter the imaging pre-preparation pulse for generating different contrast image.
3. according to the method described in claim 2, it is characterized in that, imaging of the insertion for generating different contrast image
Pre-preparation pulse, specifically includes：
Before the plane interested for exciting magnetic resonance imaging object using driving pulse, it is inserted into excitation plane upstream
The inversion pulse subsequence of arterial blood label.
4. according to the method described in claim 2, it is characterized in that, imaging of the insertion for generating different contrast image
Pre-preparation pulse, specifically includes：
It is inserted between the plane interested and acquisition magnetic resonance imaging signal of excitation magnetic resonance imaging object and is used for diffusion-weighted
The bipolar pulse gradient of imaging.
5. according to the method described in claim 1, it is characterized in that, in the sense for exciting magnetic resonance imaging object using driving pulse
Before interest plane, further include：
It is inserted into the pre-preparation pulse inhibited for water signal.
6. according to claim 1-4 any one of them methods, which is characterized in that after acquiring magnetic resonance imaging signal, adopt
Before collecting the magnetic resonant wave spectrum signal that there is water signal to inhibit, further include：
The pulse be inserted into after poly- pulse and inhibited for water signal is returned at each described 180 °.
7. the harvester of a kind of magnetic resonance imaging signal and spectroscopic signal, which is characterized in that including：
Module is encouraged, for the plane interested using driving pulse excitation magnetic resonance imaging object；
Image acquisitions module, for acquiring magnetic resonance imaging signal；
Spectroscopic signal acquisition module, for after two 180 ° times poly- pulses perpendicular to excitation plane, acquisition to have water signal
The magnetic resonant wave spectrum signal of inhibition.
8. device according to claim 7, which is characterized in that described device further includes：
It is imaged pre-preparation module, for pre- for generating the imaging of different contrast image before acquiring magnetic resonance imaging signal
Priming pulse.
9. device according to claim 8, which is characterized in that the imaging pre-preparation module is specially：For exciting
Before plane interested, the inversion pulse subsequence to the arterial blood label of excitation plane upstream is executed.
10. device according to claim 8, which is characterized in that the imaging pre-preparation module is specially：For exciting
Between plane interested and acquisition magnetic resonance imaging signal, the bipolar pulse gradient for diffusion-weighted imaging is executed.
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