CN108310007A - A kind of iodine tincture,strong disinfectant and its production method - Google Patents
A kind of iodine tincture,strong disinfectant and its production method Download PDFInfo
- Publication number
- CN108310007A CN108310007A CN201711348493.8A CN201711348493A CN108310007A CN 108310007 A CN108310007 A CN 108310007A CN 201711348493 A CN201711348493 A CN 201711348493A CN 108310007 A CN108310007 A CN 108310007A
- Authority
- CN
- China
- Prior art keywords
- iodine
- iodine tincture
- production method
- disinfectant
- strong
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/18—Iodine; Compounds thereof
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
- A01N25/02—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing liquids as carriers, diluents or solvents
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N59/00—Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
- A01N59/12—Iodine, e.g. iodophors; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pest Control & Pesticides (AREA)
- Environmental Sciences (AREA)
- Plant Pathology (AREA)
- Inorganic Chemistry (AREA)
- Dentistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Agronomy & Crop Science (AREA)
- Toxicology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Apparatus For Disinfection Or Sterilisation (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention discloses a kind of iodine tincture,strong disinfectant and its production method, including raw material and auxiliary material, the raw material includes iodine 100g and potassium iodide 75g；A kind of iodine tincture,strong disinfectant and its production method for the features such as auxiliary material includes purified water 80ml and ethyl alcohol 1000ml, and a kind of production efficiency of the present invention is high, production cost is low, and production process is simple.
Description
Technical field
The present invention relates to veterinary drug production fields, and in particular to a kind of iodine tincture,strong disinfectant and its production method.
Background technology
With the improvement of people ' s living standards and improve, people increasingly increase the demand of livestock, and animal husbandry obtains
Good development, iodine tincture disinfection agent are disinfection preservative, and mechanism of action is to make bacterium protein denaturation, death, to bacterium, very
Bacterium, virus have killing effect, currently there are iodine tincture disinfection agent etc. there are low production efficiency, production process is multiple
Disadvantage miscellaneous, of high cost, it is therefore desirable to which a kind of new scheme solves.
Invention content
In order to overcome the shortcomings of the prior art among the above, the present invention is high using a kind of production efficiency, production cost is low,
A kind of iodine tincture,strong disinfectant and its production method for the features such as production process is simple.
The purpose of the present invention is what is realized by following scheme：A kind of iodine tincture,strong disinfectant, including raw material and auxiliary material, it is special
Sign is：The raw material includes iodine 100g and potassium iodide 75g；The auxiliary material includes purified water 80ml and ethyl alcohol 1000ml.
A kind of production method of iodine tincture,strong disinfectant, which is characterized in that the iodine tincture,strong sterilizes agent and process for producing same and is：
1）Purified water 80ml is obtained after drinking water is filtered by two-pass reverse osmosis, is stirred 5 minutes and is waited for after addition potassium iodide 75g
With；
2）Iodine 100g is added after the completion of previous step, stirs evenly for use；
3）It is for use to stir evenly 25 minutes formation liquids by addition ethyl alcohol 1000ml after the completion of previous step；
4）Liquid is first stirred under the pressure of 500bar to side homogeneous 3 times after filtering after the completion of previous step, obtains dense iodine
Tincture disinfectant.
The present invention has the beneficial effect that：
Production process is simple, and production efficiency is high, and feature raw material at low cost is cheap and easy to get, and gained injection performance is steady
It is fixed, meet pharmacopeia relevant regulations, is suitble to industrialization large-scale production, therefore its application prospect is very wide.
Description of the drawings
Fig. 1 is iodine tincture,strong disinfectant production technological process of the present invention.
Specific implementation mode
Referring to Fig.1, a kind of iodine tincture,strong disinfectant, including raw material and auxiliary material, it is characterised in that：The raw material includes iodine
100g and potassium iodide 75g；The auxiliary material includes purified water 80ml and ethyl alcohol 1000ml.
A kind of production method of iodine tincture,strong disinfectant, which is characterized in that the iodine tincture,strong sterilizes agent and process for producing same and is：
1）Purified water 80ml is obtained after drinking water is filtered by two-pass reverse osmosis, is stirred 5 minutes and is waited for after addition potassium iodide 75g
With；
2）Iodine 100g is added after the completion of previous step, stirs evenly for use；
3）It is for use to stir evenly 25 minutes formation liquids by addition ethyl alcohol 1000ml after the completion of previous step；
4）Liquid is first stirred under the pressure of 500bar to side homogeneous 3 times after filtering after the completion of previous step, obtains dense iodine
Tincture disinfectant.
Embodiment
Referring to Fig.1, a kind of production method of Amoxicillin colistin sulphate injection, this technological process of production include master altogether
It operates as follows：
Process 1：Work tool used prepares
Personnel enter dispensing post by regulation, and inspection is cleared out a gathering place situation and equipment state, by tool used, utensil, liquor piping,
Agitation Tank etc. is rinsed well with purified water.
Process 2：Prepare the name of an article that ingredients personnel checks supplementary material, quantity, manufacturer, product batch number, eligible state
Deng then taking off packet is transferred in weighing, and double review is weighed the supplementary material of recipe quantity；
A. it is for use that purified water 80ml is obtained after drinking water being filtered by second level reverse osmosis apparatus, after potassium iodide 75g then is added
Stir 5 minutes for use；
B. 100g iodine is added after the completion of a steps, it is for use after ethyl alcohol 1000ml uniform stirrings being added 25 minutes after stirring evenly；
C. obtained liquid under the pressure of 500bar is being stirred into side homogeneous 3 times after filtering after the completion of b step, obtained dense
Iodine tincture disinfection agent；
Disinfectant prepare after be detected after qualification according to checked operation regulation start it is filling at bottled.
Process 3：Packing
(1) each parts for installing bottle placer fill it up with qualified rubber plug in oscillator, open bottle placer and debug loading amount, debugging
Start formal filling after qualification, jump a queue, rolls lid between lid to rolling by orbit transports；
(2) key process parameter：
Loading amount：500ml
(3) intermediate control：Loading amount detects, and checks a loading amount within every 10 minutes, and the packing semi-finished product extracted every time under different filling needles are each
3 bottles, when unlatching, pays attention to avoiding losing, and the dry injection device of content appropriate volume is taken out to the greatest extent, the corresponding of correction is then injected into
It in the drying scalar bottle of volume, inspects at room temperature, average loading amount must not be less than mark loading amount, and single loading amount must not be less than mark
The 97% of loading amount；
It jumps a queue quality testing：There must not be rubber plug button plug not rectify, buckle and fill in the inadequate phenomenon appearance of depth.
Process 4：Roll lid
(1) open Cover-rolling machine the filling product finished is carried out to roll lid, host hand rolls lid quality check at any time；
Key process parameter：Nothing；
(2) intermediate control：Lid quality testing is rolled, referring to upright screw capping with three must not loosen, and edge is smooth, and it is qualification that there must not be flash.
Process 5：Outer packing
(1) inspection verification, including the name of an article, lot number, quantity, manufacturer, eligible state are carried out to packaging material；Met by double
Labeling, mounted box, vanning are proceeded by after label preparation content is correct, are put in storage after the completion of packaging；
(2) key process parameter：Nothing；
(3) intermediate control：The inspection of imprint is checked；
Packaging material material balance：Tag class material balance is 100%, other packaging material material balances are 98-100%.It is crucial
Technique and points for attention：Inspection verification, including the name of an article, lot number, quantity, manufacturer, eligible state are carried out to supplementary material；
It carries out and weighs and check；
When preparation, it is necessary to which operated by two people, a people master match, people review, the addition and adjustment of each supplementary material, it is necessary to by checking
People confirms that two people must sign on record；
What the pressure in process for preparation was adjusted and prepared has finally quantitatively been intended to reviewing officer's confirmation, and has operating personnel and review
Personnel sign；
The detection for paying attention to disinfectant after preparing, including character, moisture, content etc..
Finally it should be noted that：Above example is only to illustrate the present invention and not limits technology described in the invention
Scheme；Therefore, although this specification with reference to above-mentioned each embodiment to present invention has been detailed description, this
Field it is to be appreciated by one skilled in the art that still can modify to the present invention or equivalent replacement；And all do not depart from this
The technical solution of the spirit and scope of invention and its improvement should all be covered in scope of the presently claimed invention.
Claims (2)
1. a kind of iodine tincture,strong disinfectant, including raw material and auxiliary material, it is characterised in that：The raw material includes iodine 100g and potassium iodide
75g；The auxiliary material includes purified water 80ml and ethyl alcohol 1000ml.
2. a kind of production method of iodine tincture,strong disinfectant according to claim 1, which is characterized in that the iodine tincture,strong disappears
Toxic agent production method is：
1）Purified water 80ml is obtained after drinking water is filtered by two-pass reverse osmosis, is stirred 5 minutes and is waited for after addition potassium iodide 75g
With；
2）Iodine 100g is added after the completion of previous step, stirs evenly for use；
3）It is for use to stir evenly 25 minutes formation liquids by addition ethyl alcohol 1000ml after the completion of previous step；
4）Liquid is first stirred under the pressure of 500bar to side homogeneous 3 times after filtering after the completion of previous step, obtains dense iodine
Tincture disinfectant.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711348493.8A CN108310007A (en) | 2017-12-15 | 2017-12-15 | A kind of iodine tincture,strong disinfectant and its production method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711348493.8A CN108310007A (en) | 2017-12-15 | 2017-12-15 | A kind of iodine tincture,strong disinfectant and its production method |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN108310007A true CN108310007A (en) | 2018-07-24 |
Family
ID=62892030
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201711348493.8A Pending CN108310007A (en) | 2017-12-15 | 2017-12-15 | A kind of iodine tincture,strong disinfectant and its production method |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN108310007A (en) |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1172589A (en) * | 1997-08-26 | 1998-02-11 | 龚国才 | Milk iodoprotein and its preparation onethod |
| CN101524367A (en) * | 2009-02-19 | 2009-09-09 | 济南瑞源医药科技有限责任公司 | Method for preparing discolored iodine tincture and application thereof |
| CN102335192A (en) * | 2011-10-08 | 2012-02-01 | 文山壮族苗族自治州皮肤病防治所 | Tinea pedis tincture |
-
2017
- 2017-12-15 CN CN201711348493.8A patent/CN108310007A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1172589A (en) * | 1997-08-26 | 1998-02-11 | 龚国才 | Milk iodoprotein and its preparation onethod |
| CN101524367A (en) * | 2009-02-19 | 2009-09-09 | 济南瑞源医药科技有限责任公司 | Method for preparing discolored iodine tincture and application thereof |
| CN102335192A (en) * | 2011-10-08 | 2012-02-01 | 文山壮族苗族自治州皮肤病防治所 | Tinea pedis tincture |
Non-Patent Citations (3)
| Title |
|---|
| 中国兽药典委员会: "《中华人民共和国兽药典兽药使用指南 2005年版 化学药品卷》", 30 April 2006, 中国农业出版社 * |
| 吴兹景: "浓碘酊中不同碘化钾剂量对碘稳定性的影响", 《屮国现代应用药学杂志》 * |
| 陆国金: "碘化钾在浓碘酊中的剂量调整", 《中国药师》 * |
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| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20180724 |