CN108300952A - A kind of preparation method of medical magnesium alloy bracket - Google Patents
A kind of preparation method of medical magnesium alloy bracket Download PDFInfo
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- CN108300952A CN108300952A CN201810089581.9A CN201810089581A CN108300952A CN 108300952 A CN108300952 A CN 108300952A CN 201810089581 A CN201810089581 A CN 201810089581A CN 108300952 A CN108300952 A CN 108300952A
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- magnesium alloy
- pipe
- bracket
- short tube
- medical
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- C—CHEMISTRY; METALLURGY
- C22—METALLURGY; FERROUS OR NON-FERROUS ALLOYS; TREATMENT OF ALLOYS OR NON-FERROUS METALS
- C22F—CHANGING THE PHYSICAL STRUCTURE OF NON-FERROUS METALS AND NON-FERROUS ALLOYS
- C22F1/00—Changing the physical structure of non-ferrous metals or alloys by heat treatment or by hot or cold working
- C22F1/06—Changing the physical structure of non-ferrous metals or alloys by heat treatment or by hot or cold working of magnesium or alloys based thereon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/02—Inorganic materials
- A61L31/022—Metals or alloys
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B23—MACHINE TOOLS; METAL-WORKING NOT OTHERWISE PROVIDED FOR
- B23P—METAL-WORKING NOT OTHERWISE PROVIDED FOR; COMBINED OPERATIONS; UNIVERSAL MACHINE TOOLS
- B23P15/00—Making specific metal objects by operations not covered by a single other subclass or a group in this subclass
-
- C—CHEMISTRY; METALLURGY
- C22—METALLURGY; FERROUS OR NON-FERROUS ALLOYS; TREATMENT OF ALLOYS OR NON-FERROUS METALS
- C22F—CHANGING THE PHYSICAL STRUCTURE OF NON-FERROUS METALS AND NON-FERROUS ALLOYS
- C22F1/00—Changing the physical structure of non-ferrous metals or alloys by heat treatment or by hot or cold working
- C22F1/02—Changing the physical structure of non-ferrous metals or alloys by heat treatment or by hot or cold working in inert or controlled atmosphere or vacuum
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- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- Thermal Sciences (AREA)
- Crystallography & Structural Chemistry (AREA)
- Materials Engineering (AREA)
- Metallurgy (AREA)
- Organic Chemistry (AREA)
- Physics & Mathematics (AREA)
- Surgery (AREA)
- General Health & Medical Sciences (AREA)
- Inorganic Chemistry (AREA)
- Vascular Medicine (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Heart & Thoracic Surgery (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Materials For Medical Uses (AREA)
- Media Introduction/Drainage Providing Device (AREA)
- Forging (AREA)
- Metal Extraction Processes (AREA)
Abstract
A kind of preparation method of medical magnesium alloy bracket, its main feature is that：The method of hot-swage is used to prepare the magnesium alloy pipe of small dimension first；Then magnesium alloy pipe is directly carried out to the drawing processing of multi-pass, and combine intermediate annealing process, obtains magnesium alloy thin-wall pipe；Magnesium alloy thin-wall pipe is finally cut into short tube and carries out laser engraving into medical magnesium alloy bracket.The present invention prepares the magnesium alloy pipe of small dimension using hot-swage method, and realize magnesium alloy pipe main road time deflection processing, to improve processing efficiency, reduce production cost, the surface quality of obtained magnesium alloy bracket is good, dimensional accuracy is high, can be used for the clinical application of such as cardiovascular inner support of internal medicine intervention apparatus.
Description
Technical field
The present invention relates to metal material processing technical fields, are specifically related to a kind of preparation side of medical magnesium alloy bracket
Method.
Background technology
Using the holder of the non-degradable material such as making such as stainless steel, cochrome and Nitinol in angiocardiopathy etc.
Aspect obtains wide application, solves the state of an illness of the Diseases such as angiocarpy to a certain extent, but these holders are being controlled
Reangiostenosis easily occurs during treating in vivo, causes embolism reaction, chronic inflammatory reaction, endometrial hyperplasia, vessel endothelialisation mistake
Cheng Yanchi and side effects, these problems such as toxic metal ions are released in human body strongly limit the development of non-degradable material
And application.
Magnesium alloy has degradable, good biocompatibility, low cause bolt, low inflammatory reaction and close to people in human body
The distinguishing features such as the mechanical property of bone can effectively solve the side effect that non-degradable material generates in human body, have become most
Promising degradable blood vessel bracket material is the hot spot of domestic and international bio-medical material educational circles research.But magnesium alloy has
Patterns for Close-Packed Hexagonal Crystal structure, deformation at room temperature working ability are very limited, and lead to magnesium alloy bracket processing difficulties, efficiency
It is low, production cost is high, significantly limit application of the magnesium alloy bracket in cardiovascular treatment field.
Invention content
It is above-mentioned there are problem and shortage it is an object of the invention to be directed to, provide a kind of simple for process, easy processing molding, at
The preparation method of this low medical magnesium alloy bracket.
The technical proposal of the invention is realized in this way：
The preparation method of medical magnesium alloy bracket of the present invention, its main feature is that：The method of hot-swage is used to prepare first
The magnesium alloy pipe of small dimension；Then by magnesium alloy pipe after surface clean, the drawing processing of multi-pass is directly carried out, and
It is aided with necessary intermediate annealing process, obtains magnesium alloy thin-wall pipe；Then magnesium alloy thin-wall pipe is cut into short tube and clear
After washing, short tube is subjected to laser engraving into medical magnesium alloy bracket；
Its specific preparation process is as follows：
Step 1：After the plug for newborn lubricant of graphiting is inserted into magnesium-alloy tube, multi-pass is carried out at 350 DEG C~450 DEG C
Hot spinning is processed, and the magnesium alloy pipe that outer diameter is 6.0~8.0mm, wall thickness is 0.5~1.2mm is obtained；
Step 2：By magnesium alloy pipe after surface clean, drawn using 5~20 vice-minister's core bar drawings processing or long core bar
It pulls out and is processed into the magnesium alloy thin-wall pipe that outer diameter is 2.0~4.0mm, wall thickness is 0.1~0.3mm in conjunction with empty drawing, every time drawing
It is 5~20% to dial deflection, uses vegetable oil as lubricant in drawing process, and implements 3~10 vacuum annealings, annealing temperature
Degree is 300~400 DEG C, annealing time 1h；
Step 3：After magnesium alloy thin-wall pipe is cut into short tube and is cleaned, short tube is subjected to laser engraving, to which surface be made
Medical magnesium alloy bracket high-quality, dimensional accuracy is high.
Compared with prior art, the present invention having following remarkable advantage：
1) present invention prepares the magnesium alloy pipe of small dimension using hot-swage method, can be held using magnesium alloy under hot-swage processing conditions
It is plastically deformed by larger three-dimensional compressive stress, realizes the big pass deformation processing of magnesium alloy, to improve processing efficiency,
Reduce production cost；
2) magnesium alloy bracket surface quality of the invention is good, dimensional accuracy is high, can be used for such as cardiovascular interior branch of internal medicine intervention apparatus
The clinical application of frame etc..
Specific implementation mode
The preparation method of medical magnesium alloy bracket of the present invention uses the method for hot-swage to prepare small dimension first
Magnesium alloy pipe；Then by magnesium alloy pipe after surface clean, the drawing processing of multi-pass is directly carried out, and being aided with must
The intermediate annealing process wanted obtains magnesium alloy thin-wall pipe；It then, will after magnesium alloy thin-wall pipe being cut into short tube and being cleaned
Short tube carries out laser engraving into medical magnesium alloy bracket；
Its specific preparation process is as follows：
Step 1：After the plug for newborn lubricant of graphiting is inserted into magnesium-alloy tube, multi-pass is carried out at 350 DEG C~450 DEG C
Hot spinning is processed, and the magnesium alloy pipe that outer diameter is 6.0~8.0mm, wall thickness is 0.5~1.2mm is obtained；
Step 2：By magnesium alloy pipe after surface clean, drawn using 5~20 vice-minister's core bar drawings processing or long core bar
It pulls out and is processed into the magnesium alloy thin-wall pipe that outer diameter is 2.0~4.0mm, wall thickness is 0.1~0.3mm in conjunction with empty drawing, every time drawing
It is 5~20% to dial deflection, uses vegetable oil as lubricant in drawing process, and implements 3~10 vacuum annealings, annealing temperature
Degree is 300~400 DEG C, annealing time 1h；
Step 3：After magnesium alloy thin-wall pipe is cut into short tube and is cleaned, short tube is subjected to laser engraving, to which surface be made
Medical magnesium alloy bracket high-quality, dimensional accuracy is high.
Below by specific embodiment, the present invention is further illustrated.
Embodiment 1：
The AZ31 magnesium alloy brackets that outer diameter is 4.0mm, wall thickness 0.3mm, length are 30mm are prepared through the invention.
It is 12.0mm, after the AZ31 magnesium-alloy tubes that wall thickness is 2.0mm that the plug for newborn lubricant of graphiting, which is inserted into outer diameter,
The processing of two passage hot spinnings is carried out at 350 DEG C, obtains the AZ31 magnesium alloy pipes that outer diameter is 6.5mm, wall thickness is 1.0mm；
AZ31 magnesium alloy pipes are processed into that outer diameter is 4.0mm, wall thickness is using 10 vice-minister's core bar drawings after surface clean
The AZ31 magnesium alloy thin-wall pipes of 0.3mm implement 8 vacuum between every time drawing group deflection is 5~20% in drawing process
Annealing, vacuum annealing temperature are 400 DEG C, annealing time 1h, use vegetable oil as lubricant in drawing process；By AZ31 magnesium
Alloy thin-wall tubing cuts into short tube, carries out laser engraving after short tube is cleaned, obtains the doctor that surface quality is good, dimensional accuracy is high
With magnesium alloy bracket, holder outer diameter is 4.0mm, wall thickness 0.3mm, length 30mm.
Embodiment 2：
The AZ31 magnesium alloy brackets that outer diameter is 2.0mm, wall thickness 0.1mm, length are 20mm are prepared through the invention.
It is 10.0mm, after the AZ31 magnesium-alloy tubes that wall thickness is 1.5mm that the plug for newborn lubricant of graphiting, which is inserted into outer diameter,
The processing of two passage hot spinnings is carried out at 350 DEG C, obtains the AZ31 magnesium alloy pipes that outer diameter is 6.0mm, wall thickness is 0.65mm；
AZ31 magnesium alloy pipes are processed into that outer diameter is 3.0mm, wall thickness is by 12 vice-minister's core bar drawings after surface clean
The AZ31 magnesium alloy thin-wall pipes of 0.15mm are then passed through 5 passage sky drawings and are processed into that outer diameter is 2.0mm, wall thickness is 0.1mm's
AZ31 magnesium alloy thin-wall pipes implement 10 vacuum annealings, very between every time drawing group deflection is 5~20% in drawing process
Empty annealing temperature is 400 DEG C, annealing time 1h, uses vegetable oil as lubricant in drawing process；By AZ31 magnesium alloy thins
Wall tube material cuts into short tube, and laser engraving is carried out after short tube is cleaned, and obtains the medical magnesium that surface quality is good, dimensional accuracy is high and closes
Golden holder, holder outer diameter is 2.0mm, wall thickness 0.1mm, length 20mm.
The present invention is described by embodiment, but is not limited the invention, with reference to description of the invention, institute
Other variations of disclosed embodiment, are such as readily apparent that the professional person of this field, such variation should belong to
Within the scope of the claims in the present invention limit.
Claims (1)
1. a kind of preparation method of medical magnesium alloy bracket, it is characterised in that：The method of hot-swage is used to prepare small rule first
The magnesium alloy pipe of lattice；Then by magnesium alloy pipe after surface clean, the drawing processing of multi-pass is directly carried out, and is aided with
Necessary intermediate annealing process obtains magnesium alloy thin-wall pipe；Then after magnesium alloy thin-wall pipe being cut into short tube and being cleaned,
Short tube is subjected to laser engraving into medical magnesium alloy bracket；
Its specific preparation process is as follows：
Step 1：After the plug for newborn lubricant of graphiting is inserted into magnesium-alloy tube, multi-pass is carried out at 350 DEG C~450 DEG C
Hot spinning is processed, and the magnesium alloy pipe that outer diameter is 6.0~8.0mm, wall thickness is 0.5~1.2mm is obtained；
Step 2：By magnesium alloy pipe after surface clean, drawn using 5~20 vice-minister's core bar drawings processing or long core bar
It pulls out and is processed into the magnesium alloy thin-wall pipe that outer diameter is 2.0~4.0mm, wall thickness is 0.1~0.3mm in conjunction with empty drawing, every time drawing
It is 5~20% to dial deflection, uses vegetable oil as lubricant in drawing process, and implements 3~10 vacuum annealings, annealing temperature
Degree is 300~400 DEG C, annealing time 1h；
Step 3：After magnesium alloy thin-wall pipe is cut into short tube and is cleaned, short tube is subjected to laser engraving, to which surface be made
Medical magnesium alloy bracket high-quality, dimensional accuracy is high.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710720437 | 2017-08-21 | ||
| CN2017107204376 | 2017-08-21 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN108300952A true CN108300952A (en) | 2018-07-20 |
| CN108300952B CN108300952B (en) | 2019-12-10 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810089581.9A Active CN108300952B (en) | 2017-08-21 | 2018-01-30 | preparation method of medical magnesium alloy stent |
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| CN (1) | CN108300952B (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110743933A (en) * | 2019-10-29 | 2020-02-04 | 西北有色金属研究院 | Thermal processing method of medical cobalt-based alloy small and micro pipe |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101357089A (en) * | 2008-09-12 | 2009-02-04 | 西北有色金属研究院 | Production method of biology degradable magnesium alloy vascular inner rack |
| CN103394545A (en) * | 2013-07-30 | 2013-11-20 | 上海交通大学 | Precise machining method for capillary tube for biodegradable magnesium alloy intravascular stent |
| CN104619358A (en) * | 2012-08-03 | 2015-05-13 | 独立行政法人产业技术总合研究所 | Thin, narrow tube; drawing device for producing same; and drawing method |
| CN105414426A (en) * | 2015-12-11 | 2016-03-23 | 西北有色金属研究院 | Hot rotary forging method of zinc alloy small-specification pipe or rod |
-
2018
- 2018-01-30 CN CN201810089581.9A patent/CN108300952B/en active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101357089A (en) * | 2008-09-12 | 2009-02-04 | 西北有色金属研究院 | Production method of biology degradable magnesium alloy vascular inner rack |
| CN104619358A (en) * | 2012-08-03 | 2015-05-13 | 独立行政法人产业技术总合研究所 | Thin, narrow tube; drawing device for producing same; and drawing method |
| CN103394545A (en) * | 2013-07-30 | 2013-11-20 | 上海交通大学 | Precise machining method for capillary tube for biodegradable magnesium alloy intravascular stent |
| CN105414426A (en) * | 2015-12-11 | 2016-03-23 | 西北有色金属研究院 | Hot rotary forging method of zinc alloy small-specification pipe or rod |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110743933A (en) * | 2019-10-29 | 2020-02-04 | 西北有色金属研究院 | Thermal processing method of medical cobalt-based alloy small and micro pipe |
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| Publication number | Publication date |
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| CN108300952B (en) | 2019-12-10 |
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Address after: 510651 No. 363, Changxin Road, Guangzhou, Guangdong, Tianhe District Patentee after: Institute of materials and processing, Guangdong Academy of Sciences Address before: 510651 No. 363, Changxin Road, Guangzhou, Guangdong, Tianhe District Patentee before: Guangdong Institute Of Materials And Processing |
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Effective date of registration: 20221109 Address after: 510651 No. 363, Changxin Road, Guangzhou, Guangdong, Tianhe District Patentee after: Institute of new materials, Guangdong Academy of Sciences Address before: 510651 No. 363, Changxin Road, Guangzhou, Guangdong, Tianhe District Patentee before: Institute of materials and processing, Guangdong Academy of Sciences |