CN108295199A - A kind of pharmaceutical composition for treating stomach trouble - Google Patents

A kind of pharmaceutical composition for treating stomach trouble Download PDF

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Publication number
CN108295199A
CN108295199A CN201810290105.3A CN201810290105A CN108295199A CN 108295199 A CN108295199 A CN 108295199A CN 201810290105 A CN201810290105 A CN 201810290105A CN 108295199 A CN108295199 A CN 108295199A
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Prior art keywords
parts
pharmaceutical composition
treatment
stomach trouble
added
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CN201810290105.3A
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Inventor
李梦琦
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Suzhou Tianling Chinese Traditional Medicine Slice Co Ltd
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Suzhou Tianling Chinese Traditional Medicine Slice Co Ltd
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Priority to CN201810290105.3A priority Critical patent/CN108295199A/en
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    • A—HUMAN NECESSITIES
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
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    • A61K31/19—Carboxylic acids, e.g. valproic acid
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    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
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Abstract

The invention discloses a kind of pharmaceutical composition for treating stomach trouble, described pharmaceutical composition includes main material and auxiliary material；The main material is prepared by the raw material of following parts by weight：8 17 parts of walnut diaphragma juglandis, 3 11 parts of fennel, 5 12 parts of Sargent gloryvine, 37 parts of aspongopus, 48 parts of finger citron sliced, 4 11 parts of argy wormwood, 5 12 parts of wrinkled giant hyssop, 6 10 parts of cassia twig, 49 parts of polygonum flaccidum, 6 13 parts of sweet potato leaves, 3 10 parts of licorice, 4 10 parts of cape jasmine.Pharmaceutical composition prepared by the present invention can effectively treat chronic gastropathy, quick, short treating period, it is treated total effective rate and may be up to 90% or more after taking 20 days, easy to use, has no toxic side effect, has wide potential applicability in clinical practice.

Description

A kind of pharmaceutical composition for treating stomach trouble
Technical field
The invention belongs to pharmaceutical technology fields, and in particular to a kind of pharmaceutical composition for treating stomach trouble.
Background technology
Disease of digestive system includes the organic and functional disease of the internal organs such as oesophagus, stomach, intestines, liver, courage, pancreas, clinically Very common, wherein chronic gastritis incidence ranks first in various stomach trouble, and for clinical common frdquently encountered disease, the course of disease is long, easily anti- It is multiple, it is often refractory.Clinical common patient has indigestion performance, such as sour regurgitation, heating, early satiety, anorexia, nausea.It is chronic Apparent apocleisis and weight loss can occur in atrophic gastritis, and with anaemia.Chronic gastritis refer to a variety of adverse factors repeatedly Damage, leads to the chronic inflammatory diseases of gastric mucosa.
Chronic gastritis refers to stomach lining chronic inflammation caused by different pathogeny, since self-digestion scope extensive use, to this disease Understanding is significantly improved, and etiology and pathogenesis not yet illustrates completely, may be related with following 5 factors：（1）Acute gastritis Sequel：After acute gastritis, gastric mucosal lesions are not cured persistently or recurrent exerbation, can form chronic gastritis；（2）Irritation is eaten Object and drug；（3）The reflux of duodenal juice enters stomach；（4）The generation of certain autoimmune diseases, such as chronic thyroiditis, first Shape hypoadenia or hyperfunction, insulin-dependent diabetes mellitus, chronic adrenocortical insufficiency etc.；（5）Virus infection because Element.For in the treatment of chronic gastritis, relative to western medical treatment, Chinese traditional treatment is secondary without poison to human body since its pharmacological property is mild Effect, can fundamentally eradicate stomach trouble, and uneasy to recur, and be concerned.It is controlled however, Chronic Gastritis Clinic Cured by Chinese Medicine often exists Therapeutic effect is slow, and the pharmacological property of Chinese medicine is easily reduced by high-temperature process, influences therapeutic effect.There is provided as a result, it is a kind of it is novel, The pharmaceutical composition for the chronic gastritis that therapeutic effect is good and curative effect is fast has important practice significance.
Invention content
For this purpose, the present invention provides a kind of pharmaceutical composition for treating stomach trouble, solves at least one of prior art technology and ask Topic.
For this purpose, the present invention provides a kind of pharmaceutical composition for treating stomach trouble, described pharmaceutical composition includes main material and auxiliary Raw material；The main material is prepared by the raw material of following parts by weight：8-17 parts of walnut diaphragma juglandis, 3-11 parts of fennel, Sargent gloryvine 5- 12 parts, 3-7 parts of aspongopus, 4-8 parts of finger citron sliced, 4-11 parts of argy wormwood, 5-12 parts of wrinkled giant hyssop, 6-10 parts of cassia twig, 4-9 parts of polygonum flaccidum, sweet potato 6-13 parts of leaf, 3-10 parts of licorice, 4-10 parts of cape jasmine；
The auxiliary material is prepared by the raw material of following parts by weight：4-8 parts of Chinese prickly ash, 2-7 parts of black fungus, 6-11 parts of bluish dogbane, 4-10 parts of olive oil, 5-12 parts of rice bran oil chaff, 2-6 parts of calcium citrate, 3-6 parts of cupreol.
According to embodiment of the present invention, wherein the mass ratio of the main material and auxiliary material is 1:0.05-0.3.
According to embodiment of the present invention, wherein the main material is prepared by the raw material of following parts by weight：Core 9-16 parts of peach diaphragma juglandis, 5-10 parts of fennel, 6-11 parts of Sargent gloryvine, 4-7 parts of aspongopus, 4-7 parts of finger citron sliced, 7-10 parts of argy wormwood, wrinkled giant hyssop 6-10 parts, 7-9 parts of cassia twig, 6-9 parts of polygonum flaccidum, 6-11 parts of sweet potato leaves, 4-10 parts of licorice, 6-9 parts of cape jasmine.
According to embodiment of the present invention, wherein the auxiliary material is prepared by the raw material of following parts by weight：Flower 4.5-7.3 parts of green pepper, 2.9-6.5 parts of black fungus, 6.8-10 parts of bluish dogbane, 4.5-9.4 parts of olive oil, 5.2-11 parts of rice bran oil chaff, lemon 3-5.8 parts of lemon acid calcium, 3.6-5.2 parts of cupreol.
According to embodiment of the present invention, wherein the preparation process of described pharmaceutical composition is：
1）Chinese prickly ash, black fungus and bluish dogbane is finely ground, be placed in enzymatic vessel, 50-70 DEG C of purified water is added, solid-liquid ratio is 1:1-3h is mixed in 8-15, and dimension element enzyme and pectase that mass fraction is 2% is then added, 24- is stood at 37-45 DEG C 48h, filtering, filtrate is uniformly mixed with calcium citrate, the olive oil of cupreol and sterilized processing, rice bran oil chaff, is freezed It is dried to obtain freeze-dried powder；
2）By walnut diaphragma juglandis, fennel, Sargent gloryvine, aspongopus, finger citron sliced, argy wormwood, wrinkled giant hyssop, cassia twig, polygonum flaccidum, sweet potato leaves, licorice It is added water to cook 2-5 times with cape jasmine, collects volatile oil and decoction liquor, it is 1.13-1.2 that decoction liquor, which is condensed into relative density, is added The ethyl alcohol of 80-95% carries out alcohol precipitation, filters and concentrate filtrate, decompression later, dry condensed cream；
3）Above-mentioned freeze-dried powder and condensed cream are uniformly mixed, dispersant and the volatile oil mixed grinding in 40-70 DEG C of water-bath is added, The Chinese medicine composition for the treatment of stomach trouble is made.
According to embodiment of the present invention, wherein the condition of the inactivation treatment is：Olive oil, rice bran oil chaff are existed Sterilization treatment 20-60min at 75-85 DEG C.
According to embodiment of the present invention, wherein the carrier that above-mentioned Chinese medicine composition is added and is pharmaceutically received The Chinese medicine preparation of different form of Chinese drug is made together with auxiliary material.
According to embodiment of the present invention, wherein the dispersant is polyethylene glycol 2000.
According to embodiment of the present invention, wherein the dosage form of described pharmaceutical composition is selected from powder, tablet, particle Any one of agent, capsule, solution, emulsion and suspension.
Beneficial effects of the present invention are：
Pharmaceutical composition prepared by the present invention can effectively treat chronic gastropathy, quick, short treating period, after taking 20 days its Treatment total effective rate may be up to 90% or more, easy to use, have no toxic side effect, and have wide potential applicability in clinical practice.
Specific implementation mode
With reference to embodiment, present invention is further described in detail.Following embodiment is not for illustrating the present invention, but not For limiting the scope of the invention.
Embodiment 1
A kind of pharmaceutical composition for treating stomach trouble, described pharmaceutical composition include main material and auxiliary material；The main material by with The raw material of lower parts by weight is prepared：8 parts of walnut diaphragma juglandis, 3 parts of fennel, 5 parts of Sargent gloryvine, 3 parts of aspongopus, 4 parts of finger citron sliced, argy wormwood 4 parts, 5 parts of wrinkled giant hyssop, 6 parts of cassia twig, 4 parts of polygonum flaccidum, 6 parts of sweet potato leaves, 3 parts of licorice, 4 parts of cape jasmine；
The auxiliary material is prepared by the raw material of following parts by weight：4 parts of Chinese prickly ash, 2 parts of black fungus, 6 parts of bluish dogbane, olive oil 4 Part, 5 parts of rice bran oil chaff, 2 parts of calcium citrate, 3 parts of cupreol.
The mass ratio of the main material and auxiliary material is 1:0.05.
The preparation process of described pharmaceutical composition is：
1）Chinese prickly ash, black fungus and bluish dogbane is finely ground, be placed in enzymatic vessel, be added 50 DEG C of purified waters, solid-liquid ratio 1: 8,1h is mixed, dimension element enzyme and pectase that mass fraction is 2% is then added, is stood at 37 DEG C for 24 hours, filtering will filter Liquid is uniformly mixed with calcium citrate, the olive oil of cupreol and sterilized processing, rice bran oil chaff, is lyophilized Powder；The condition of the inactivation treatment is：By olive oil, rice bran oil chaff at 75 DEG C sterilization treatment 20min；
2）By walnut diaphragma juglandis, fennel, Sargent gloryvine, aspongopus, finger citron sliced, argy wormwood, wrinkled giant hyssop, cassia twig, polygonum flaccidum, sweet potato leaves, licorice It is added water to cook 2-5 times with cape jasmine, collects volatile oil and decoction liquor, it is 1.13-1.2 that decoction liquor, which is condensed into relative density, is added The ethyl alcohol of 80-95% carries out alcohol precipitation, filters and concentrate filtrate, decompression later, dry condensed cream；
3）Above-mentioned freeze-dried powder and condensed cream are uniformly mixed, polyethylene glycol 2000 dispersant and volatile oil is added in 40 DEG C of water-baths The Chinese medicine composition for the treatment of stomach trouble is made in mixed grinding.
Embodiment 2
A kind of pharmaceutical composition for treating stomach trouble, described pharmaceutical composition include main material and auxiliary material；The main material by with The raw material of lower parts by weight is prepared：17 parts of walnut diaphragma juglandis, 11 parts of fennel, 12 parts of Sargent gloryvine, 7 parts of aspongopus, 8 parts of finger citron sliced, 11 parts of argy wormwood, 12 parts of wrinkled giant hyssop, 10 parts of cassia twig, 9 parts of polygonum flaccidum, 13 parts of sweet potato leaves, 10 parts of licorice, 10 parts of cape jasmine；
The auxiliary material is prepared by the raw material of following parts by weight：8 parts of Chinese prickly ash, 7 parts of black fungus, 11 parts of bluish dogbane, olive oil 10 parts, 12 parts of rice bran oil chaff, 6 parts of calcium citrate, 6 parts of cupreol.
The mass ratio of the main material and auxiliary material is 1:0.3.
The preparation process of described pharmaceutical composition is：
1）Chinese prickly ash, black fungus and bluish dogbane is finely ground, be placed in enzymatic vessel, be added 70 DEG C of purified waters, solid-liquid ratio 1: 15,3h is mixed, dimension element enzyme and pectase that mass fraction is 2% is then added, 48h is stood at 45 DEG C, filters, it will Filtrate is uniformly mixed with calcium citrate, the olive oil of cupreol and sterilized processing, rice bran oil chaff, is lyophilized Powder；The condition of the inactivation treatment is：By olive oil, rice bran oil chaff at 85 DEG C sterilization treatment 60min；
2）By walnut diaphragma juglandis, fennel, Sargent gloryvine, aspongopus, finger citron sliced, argy wormwood, wrinkled giant hyssop, cassia twig, polygonum flaccidum, sweet potato leaves, licorice It is added water to cook 5 times with cape jasmine, collects volatile oil and decoction liquor, it is 1.2 that decoction liquor, which is condensed into relative density, and 95% second is added Alcohol carries out alcohol precipitation, filters and concentrate filtrate, decompression later, dry condensed cream；
3）Above-mentioned freeze-dried powder and condensed cream are uniformly mixed, polyethylene glycol 2000 dispersant and volatile oil is added in 70 DEG C of water-baths The Chinese medicine composition for the treatment of stomach trouble is made in mixed grinding.
Embodiment 3
A kind of pharmaceutical composition for treating stomach trouble, described pharmaceutical composition include main material and auxiliary material；The main material by with The raw material of lower parts by weight is prepared：9 parts of walnut diaphragma juglandis, 5 parts of fennel, 6 parts of Sargent gloryvine, 4 parts of aspongopus, 4 parts of finger citron sliced, argy wormwood 7 parts, 6 parts of wrinkled giant hyssop, 7 parts of cassia twig, 6 parts of polygonum flaccidum, 6 parts of sweet potato leaves, 4 parts of licorice, 6 parts of cape jasmine；
The auxiliary material is prepared by the raw material of following parts by weight：4.5 parts of Chinese prickly ash, 2.9 parts of black fungus, 6.8 parts of bluish dogbane, olive 4.5 parts of olive oil, 5.2 parts of rice bran oil chaff, 3 parts of calcium citrate, 3.6 parts of cupreol.
The mass ratio of the main material and auxiliary material is 1:0.08.
The preparation process of described pharmaceutical composition is：
1）Chinese prickly ash, black fungus and bluish dogbane is finely ground, be placed in enzymatic vessel, be added 60 DEG C of purified waters, solid-liquid ratio 1: 10,2h is mixed, dimension element enzyme and pectase that mass fraction is 2% is then added, 36h is stood at 40 DEG C, filters, it will Filtrate is uniformly mixed with calcium citrate, the olive oil of cupreol and sterilized processing, rice bran oil chaff, is lyophilized Powder；The condition of the inactivation treatment is：By olive oil, rice bran oil chaff at 80 DEG C sterilization treatment 45min；
2）By walnut diaphragma juglandis, fennel, Sargent gloryvine, aspongopus, finger citron sliced, argy wormwood, wrinkled giant hyssop, cassia twig, polygonum flaccidum, sweet potato leaves, licorice It is added water to cook 4 times with cape jasmine, collects volatile oil and decoction liquor, it is 1.16 that decoction liquor, which is condensed into relative density, and 85% second is added Alcohol carries out alcohol precipitation, filters and concentrate filtrate, decompression later, dry condensed cream；
3）Above-mentioned freeze-dried powder and condensed cream are uniformly mixed, polyethylene glycol 2000 dispersant and volatile oil is added in 55 DEG C of water-baths The Chinese medicine composition for the treatment of stomach trouble is made in mixed grinding.
Embodiment 4
A kind of pharmaceutical composition for treating stomach trouble, described pharmaceutical composition include main material and auxiliary material；The main material by with The raw material of lower parts by weight is prepared：16 parts of walnut diaphragma juglandis, 10 parts of fennel, 11 parts of Sargent gloryvine, 7 parts of aspongopus, 7 parts of finger citron sliced, 10 parts of argy wormwood, 10 parts of wrinkled giant hyssop, 9 parts of cassia twig, 9 parts of polygonum flaccidum, 11 parts of sweet potato leaves, 10 parts of licorice, 9 parts of cape jasmine；
The auxiliary material is prepared by the raw material of following parts by weight：7.3 parts of Chinese prickly ash, 6.5 parts of black fungus, 10 parts of bluish dogbane, olive 9.4 parts of olive oil, 11 parts of rice bran oil chaff, 5.8 parts of calcium citrate, 5.2 parts of cupreol.
The mass ratio of the main material and auxiliary material is 1:0.12.
The preparation process of described pharmaceutical composition is：
1）Chinese prickly ash, black fungus and bluish dogbane is finely ground, be placed in enzymatic vessel, be added 60 DEG C of purified waters, solid-liquid ratio 1: 10,2h is mixed, dimension element enzyme and pectase that mass fraction is 2% is then added, 36h is stood at 42 DEG C, filters, it will Filtrate is uniformly mixed with calcium citrate, the olive oil of cupreol and sterilized processing, rice bran oil chaff, is lyophilized Powder；The condition of the inactivation treatment is：By olive oil, rice bran oil chaff at 80 DEG C sterilization treatment 50min；
2）By walnut diaphragma juglandis, fennel, Sargent gloryvine, aspongopus, finger citron sliced, argy wormwood, wrinkled giant hyssop, cassia twig, polygonum flaccidum, sweet potato leaves, licorice It is added water to cook 4 times with cape jasmine, collects volatile oil and decoction liquor, it is 1.18 that decoction liquor, which is condensed into relative density, and 85% second is added Alcohol carries out alcohol precipitation, filters and concentrate filtrate, decompression later, dry condensed cream；
3）Above-mentioned freeze-dried powder and condensed cream are uniformly mixed, polyethylene glycol 2000 dispersant and volatile oil is added in 55 DEG C of water-baths The Chinese medicine composition for the treatment of stomach trouble is made in mixed grinding.
Embodiment 5
A kind of pharmaceutical composition for treating stomach trouble, described pharmaceutical composition include main material and auxiliary material；The main material by with The raw material of lower parts by weight is prepared：12 parts of walnut diaphragma juglandis, 7 parts of fennel, 8 parts of Sargent gloryvine, 5 parts of aspongopus, 6 parts of finger citron sliced, Chinese mugwort 8.5 parts of wormwood artemisia, 7 parts of wrinkled giant hyssop, 7.8 parts of cassia twig, 8 parts of polygonum flaccidum, 9 parts of sweet potato leaves, 8.5 parts of licorice, 7 parts of cape jasmine；
The auxiliary material is prepared by the raw material of following parts by weight：6.2 parts of Chinese prickly ash, 4.4 parts of black fungus, 7.6 parts of bluish dogbane, olive 8.2 parts of olive oil, 6.5 parts of rice bran oil chaff, 4.3 parts of calcium citrate, 5 parts of cupreol.
The mass ratio of the main material and auxiliary material is 1:0.15.
The preparation process of described pharmaceutical composition is：
1）Chinese prickly ash, black fungus and bluish dogbane is finely ground, be placed in enzymatic vessel, be added 65 DEG C of purified waters, solid-liquid ratio 1: 12,2h is mixed, dimension element enzyme and pectase that mass fraction is 2% is then added, 48h is stood at 42 DEG C, filters, it will Filtrate is uniformly mixed with calcium citrate, the olive oil of cupreol and sterilized processing, rice bran oil chaff, is lyophilized Powder；The condition of the inactivation treatment is：By olive oil, rice bran oil chaff at 80 DEG C sterilization treatment 50min；
2）By walnut diaphragma juglandis, fennel, Sargent gloryvine, aspongopus, finger citron sliced, argy wormwood, wrinkled giant hyssop, cassia twig, polygonum flaccidum, sweet potato leaves, licorice It is added water to cook 4 times with cape jasmine, collects volatile oil and decoction liquor, it is 1.17 that decoction liquor, which is condensed into relative density, and 85% second is added Alcohol carries out alcohol precipitation, filters and concentrate filtrate, decompression later, dry condensed cream；
3）Above-mentioned freeze-dried powder and condensed cream are uniformly mixed, polyethylene glycol 2000 dispersant and volatile oil is added in 65 DEG C of water-baths The Chinese medicine composition for the treatment of stomach trouble is made in mixed grinding.
Above-mentioned Chinese medicine composition is added together with the carrier and auxiliary material that pharmaceutically receive and is made in different form of Chinese drug Medicine preparation.The dosage form of described pharmaceutical composition is in powder, tablet, granule, capsule, solution, emulsion and suspension It is any.
Comparative example 1
This comparative example difference from example 1 is that：Walnut diaphragma juglandis and rice bran oil chaff are free of in this comparative example.
Comparative example 2
This comparative example difference from example 1 is that：Finger citron sliced, black fungus and bluish dogbane are free of in this comparative example.
Performance test
Select each 50 of patients with gastric disease, wherein each 25 of men and women.According to the state of an illness, the above pharmaceutical composition 5g/ is taken orally every time respectively It is secondary, it three times a day, takes 20 days, and observe therapeutic effect, drug identical with its effect is refused to obey during medication.
Curative effect judging standard：
The record of cardinal symptom the standard of curative effect evaluation Primary Reference cardinal symptom (epigastric pain and turgor) and evaluation.Improve by symptom Total mark * 100% before percentage=(total mark after total mark-treatment before treatment)/treatment, calculating cardinal symptom improves percentage Rate.
It is effective：Symptom improves percentage >=80%.
Effectively：50%≤symptom improves percentage<80%.
In vain：Symptom improves percentage<50%.
Therapeutic evaluation：
It is quick by the above test result it is found that the pharmaceutical composition prepared by the present invention can effectively treat chronic gastropathy, Short treating period, it is treated total effective rate and may be up to 90% or more after taking 20 days, easy to use, has no toxic side effect, potential applicability in clinical practice Well.

Claims (9)

1. a kind of pharmaceutical composition for treating stomach trouble, which is characterized in that described pharmaceutical composition includes main material and auxiliary material；Institute Main material is stated to be prepared by the raw material of following parts by weight：8-17 parts of walnut diaphragma juglandis, 3-11 parts of fennel, 5-12 parts of Sargent gloryvine, nine Fragrant worm 3-7 parts, 4-8 parts of finger citron sliced, 4-11 parts of argy wormwood, 5-12 parts of wrinkled giant hyssop, 6-10 parts of cassia twig, 4-9 parts of polygonum flaccidum, sweet potato leaves 6-13 Part, 3-10 parts of licorice, 4-10 parts of cape jasmine；
The auxiliary material is prepared by the raw material of following parts by weight：4-8 parts of Chinese prickly ash, 2-7 parts of black fungus, 6-11 parts of bluish dogbane, 4-10 parts of olive oil, 5-12 parts of rice bran oil chaff, 2-6 parts of calcium citrate, 3-6 parts of cupreol.
2. the pharmaceutical composition for the treatment of stomach trouble according to claim 1, which is characterized in that the matter of the main material and auxiliary material Amount is than being 1:0.05-0.3.
3. the pharmaceutical composition for the treatment of stomach trouble according to claim 1, which is characterized in that the main material is by following weight The raw material of part is prepared：9-16 parts of walnut diaphragma juglandis, 5-10 parts of fennel, 6-11 parts of Sargent gloryvine, 4-7 parts of aspongopus, finger citron sliced 4-7 Part, 7-10 parts of argy wormwood, 6-10 parts of wrinkled giant hyssop, 7-9 parts of cassia twig, 6-9 parts of polygonum flaccidum, 6-11 parts of sweet potato leaves, 4-10 parts of licorice, cape jasmine 6- 9 parts.
4. the pharmaceutical composition for the treatment of stomach trouble according to claim 1, which is characterized in that the auxiliary material is by following weight The raw material of part is prepared：4.5-7.3 parts of Chinese prickly ash, 2.9-6.5 parts of black fungus, 6.8-10 parts of bluish dogbane, olive oil 4.5-9.4 Part, 5.2-11 parts of rice bran oil chaff, 3-5.8 parts of calcium citrate, 3.6-5.2 parts of cupreol.
5. according to the pharmaceutical composition of any treatment stomach trouble of claim 1-4, which is characterized in that described pharmaceutical composition Preparation process be：
1）Chinese prickly ash, black fungus and bluish dogbane is finely ground, be placed in enzymatic vessel, 50-70 DEG C of purified water is added, solid-liquid ratio is 1:1-3h is mixed in 8-15, and dimension element enzyme and pectase that mass fraction is 2% is then added, 24- is stood at 37-45 DEG C 48h, filtering, filtrate is uniformly mixed with calcium citrate, the olive oil of cupreol and sterilized processing, rice bran oil chaff, is freezed It is dried to obtain freeze-dried powder；
2）By walnut diaphragma juglandis, fennel, Sargent gloryvine, aspongopus, finger citron sliced, argy wormwood, wrinkled giant hyssop, cassia twig, polygonum flaccidum, sweet potato leaves, licorice It is added water to cook 2-5 times with cape jasmine, collects volatile oil and decoction liquor, it is 1.13-1.2 that decoction liquor, which is condensed into relative density, is added The ethyl alcohol of 80-95% carries out alcohol precipitation, filters and concentrate filtrate, decompression later, dry condensed cream；
3）Above-mentioned freeze-dried powder and condensed cream are uniformly mixed, dispersant and the volatile oil mixed grinding in 40-70 DEG C of water-bath is added, The Chinese medicine composition for the treatment of stomach trouble is made.
6. the pharmaceutical composition for the treatment of stomach trouble according to claim 5, which is characterized in that the condition of the inactivation treatment For：By olive oil, rice bran oil chaff at 75-85 DEG C sterilization treatment 20-60min.
7. the pharmaceutical composition for the treatment of stomach trouble according to claim 5, which is characterized in that above-mentioned Chinese medicine composition to be added With the Chinese medicine preparation that different form of Chinese drug are made together with the carrier and auxiliary material that pharmaceutically receive.
8. the pharmaceutical composition for the treatment of stomach trouble according to claim 5, which is characterized in that the dispersant is polyethylene glycol 2000。
9. the pharmaceutical composition for the treatment of stomach trouble according to claim 1, which is characterized in that the dosage form of described pharmaceutical composition Selected from any one of powder, tablet, granule, capsule, solution, emulsion and suspension.
CN201810290105.3A 2018-04-03 2018-04-03 A kind of pharmaceutical composition for treating stomach trouble Pending CN108295199A (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101239112A (en) * 2007-02-09 2008-08-13 上海中医药大学 Chinese medicinal composition for regulating blood fat and preparation thereof
CN102258624A (en) * 2010-05-28 2011-11-30 刘国昌 Chinese medicinal composition for treating gastritis

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101239112A (en) * 2007-02-09 2008-08-13 上海中医药大学 Chinese medicinal composition for regulating blood fat and preparation thereof
CN102258624A (en) * 2010-05-28 2011-11-30 刘国昌 Chinese medicinal composition for treating gastritis

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
张富平: "胃痛热痹二则验案例析", 《实用中医内科杂志》 *
张明: "《做自己的营养医生》", 30 June 2014, 天津科学技术出版社 *
望晖: "《实用养胃护胃常识》", 31 May 2016, 成都时代出版社 *

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