CN108294802A - A kind of U-tube shape tissue ligation clip of double-layer structure and preparation method thereof - Google Patents
A kind of U-tube shape tissue ligation clip of double-layer structure and preparation method thereof Download PDFInfo
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- CN108294802A CN108294802A CN201810060437.2A CN201810060437A CN108294802A CN 108294802 A CN108294802 A CN 108294802A CN 201810060437 A CN201810060437 A CN 201810060437A CN 108294802 A CN108294802 A CN 108294802A
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- clip
- polyglycolide
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- double
- layer structure
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
- A61B17/122—Clamps or clips, e.g. for the umbilical cord
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L17/00—Materials for surgical sutures or for ligaturing blood vessels ; Materials for prostheses or catheters
- A61L17/005—Materials for surgical sutures or for ligaturing blood vessels ; Materials for prostheses or catheters containing a biologically active substance, e.g. a medicament or a biocide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L17/00—Materials for surgical sutures or for ligaturing blood vessels ; Materials for prostheses or catheters
- A61L17/06—At least partially resorbable materials
- A61L17/10—At least partially resorbable materials containing macromolecular materials
- A61L17/12—Homopolymers or copolymers of glycolic acid or lactic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
- A61B2017/12004—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord for haemostasis, for prevention of bleeding
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
- A61L2300/204—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials with nitrogen-containing functional groups, e.g. aminoxides, nitriles, guanidines
- A61L2300/206—Biguanides, e.g. chlorohexidine
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/412—Tissue-regenerating or healing or proliferative agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
- A61L2300/602—Type of release, e.g. controlled, sustained, slow
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Surgery (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Vascular Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Materials Engineering (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Reproductive Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Materials For Medical Uses (AREA)
Abstract
Description
Embodiment 2 | Embodiment 3 | Embodiment 4 | Embodiment 5 | Comparative example 1 | Comparative example 2 | Comparative example 3 | |
Viscosity (dL/g) | 3.48 | 3.62 | 3.36 | 3.85 | 2.18 | 3.28 | 1.98 |
Mold preheats (DEG C) | 50 | 60 | 70 | 70 | 70 | 70 | 50 |
Injection temperature (DEG C) | 190 | 200 | 210 | 210 | 210 | 210 | 190 |
Injection time (s) | 25 | 30 | 35 | 35 | 35 | 35 | 25 |
Heat treatment temperature (DEG C) | 40 | 50 | 60 | 50 | 60 | 60 | 40 |
Heat treatment time (h) | 2 | 3 | 4 | 5 | 4 | 4 | 2 |
Whether it is molded | It is | It is | It is | It is | It is no | It is | It is no |
Degradation time (moon) | 4 | 5 | 6 | 8 | * | 10 | * |
Sample | PT(s) | TT(s) | APTT(s) |
Fresh and healthy blood plasma | 36.64 | 16.21 | 93.82 |
Embodiment 2 | 32.56 | 14.36 | 91.86 |
Embodiment 3 | 31.42 | 14.12 | 91.04 |
Embodiment 4 | 30.12 | 13.05 | 90.13 |
Embodiment 5 | 33.38 | 14.89 | 91.32 |
Comparative example 2 | 35.12 | 15.55 | 93.36 |
Claims (8)
Priority Applications (1)
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Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
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CN111001080A (en) * | 2020-01-19 | 2020-04-14 | 管辉球 | Apparatus for cholangiography and external drainage through cystic duct |
CN111513793A (en) * | 2020-04-15 | 2020-08-11 | 浙江天松医疗器械股份有限公司 | Absorbable ligature clamp and disassembling method thereof |
CN112120753A (en) * | 2020-10-21 | 2020-12-25 | 东南大学泰州生物医药与医疗器械研究院 | Absorbable polymer hemostatic clamp |
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US5306283A (en) * | 1992-06-30 | 1994-04-26 | American Cyanamid Company | Two-part surgical ligation clip |
CN201831920U (en) * | 2010-05-20 | 2011-05-18 | 仁齐企业有限公司 | Improved structure of artery clamp |
CN201958948U (en) * | 2011-03-04 | 2011-09-07 | 付吉东 | Novel vascular clamp |
CN205322412U (en) * | 2015-12-24 | 2016-06-22 | 安瑞医疗器械(杭州)有限公司 | Controllable hemostatic clamp that drops |
CN107137755A (en) * | 2017-06-07 | 2017-09-08 | 浙江微度医疗器械有限公司 | A kind of hemostatic ligation clip that can quickly absorb |
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US5306283A (en) * | 1992-06-30 | 1994-04-26 | American Cyanamid Company | Two-part surgical ligation clip |
CN201831920U (en) * | 2010-05-20 | 2011-05-18 | 仁齐企业有限公司 | Improved structure of artery clamp |
CN201958948U (en) * | 2011-03-04 | 2011-09-07 | 付吉东 | Novel vascular clamp |
CN205322412U (en) * | 2015-12-24 | 2016-06-22 | 安瑞医疗器械(杭州)有限公司 | Controllable hemostatic clamp that drops |
CN107137755A (en) * | 2017-06-07 | 2017-09-08 | 浙江微度医疗器械有限公司 | A kind of hemostatic ligation clip that can quickly absorb |
Cited By (3)
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CN111001080A (en) * | 2020-01-19 | 2020-04-14 | 管辉球 | Apparatus for cholangiography and external drainage through cystic duct |
CN111513793A (en) * | 2020-04-15 | 2020-08-11 | 浙江天松医疗器械股份有限公司 | Absorbable ligature clamp and disassembling method thereof |
CN112120753A (en) * | 2020-10-21 | 2020-12-25 | 东南大学泰州生物医药与医疗器械研究院 | Absorbable polymer hemostatic clamp |
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