CN108289646B - Measuring device, measuring method and electronic equipment for measuring individual energy consumption - Google Patents
Measuring device, measuring method and electronic equipment for measuring individual energy consumption Download PDFInfo
- Publication number
- CN108289646B CN108289646B CN201780000137.9A CN201780000137A CN108289646B CN 108289646 B CN108289646 B CN 108289646B CN 201780000137 A CN201780000137 A CN 201780000137A CN 108289646 B CN108289646 B CN 108289646B
- Authority
- CN
- China
- Prior art keywords
- individual
- near infrared
- muscle
- measuring
- control unit
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 238000000034 method Methods 0.000 title claims abstract description 28
- 238000005265 energy consumption Methods 0.000 title claims abstract description 22
- 210000003205 muscle Anatomy 0.000 claims abstract description 113
- 238000006213 oxygenation reaction Methods 0.000 claims abstract description 69
- 230000004913 activation Effects 0.000 claims abstract description 8
- 108010054147 Hemoglobins Proteins 0.000 claims description 45
- 102000001554 Hemoglobins Human genes 0.000 claims description 45
- 238000005259 measurement Methods 0.000 claims description 35
- 230000036284 oxygen consumption Effects 0.000 claims description 27
- 230000000747 cardiac effect Effects 0.000 claims description 22
- 238000012545 processing Methods 0.000 claims description 12
- 235000019577 caloric intake Nutrition 0.000 claims description 10
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims description 8
- 229910052760 oxygen Inorganic materials 0.000 claims description 8
- 239000001301 oxygen Substances 0.000 claims description 8
- 238000009532 heart rate measurement Methods 0.000 claims description 4
- 230000003068 static effect Effects 0.000 abstract description 3
- 238000010586 diagram Methods 0.000 description 10
- 102000036675 Myoglobin Human genes 0.000 description 8
- 108010062374 Myoglobin Proteins 0.000 description 8
- 230000008569 process Effects 0.000 description 6
- 238000000691 measurement method Methods 0.000 description 5
- 230000008033 biological extinction Effects 0.000 description 4
- 230000000694 effects Effects 0.000 description 4
- 230000036541 health Effects 0.000 description 4
- 238000004497 NIR spectroscopy Methods 0.000 description 3
- 230000009471 action Effects 0.000 description 3
- 230000000284 resting effect Effects 0.000 description 3
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 208000024172 Cardiovascular disease Diseases 0.000 description 1
- 208000017667 Chronic Disease Diseases 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 108010064719 Oxyhemoglobins Proteins 0.000 description 1
- 230000001133 acceleration Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 238000004891 communication Methods 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 206010012601 diabetes mellitus Diseases 0.000 description 1
- 238000013213 extrapolation Methods 0.000 description 1
- 238000009434 installation Methods 0.000 description 1
- 230000002503 metabolic effect Effects 0.000 description 1
- 238000005457 optimization Methods 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
- A61B5/0205—Simultaneously evaluating both cardiovascular conditions and different types of body conditions, e.g. heart and respiratory condition
- A61B5/02055—Simultaneously evaluating both cardiovascular condition and temperature
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
- A61B5/026—Measuring blood flow
- A61B5/029—Measuring or recording blood output from the heart, e.g. minute volume
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves
- A61B5/053—Measuring electrical impedance or conductance of a portion of the body
- A61B5/0531—Measuring skin impedance
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/08—Detecting, measuring or recording devices for evaluating the respiratory organs
- A61B5/083—Measuring rate of metabolism by using breath test, e.g. measuring rate of oxygen consumption
- A61B5/0833—Measuring rate of oxygen consumption
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/14546—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring analytes not otherwise provided for, e.g. ions, cytochromes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
- A61B5/14551—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases
- A61B5/14552—Details of sensors specially adapted therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/45—For evaluating or diagnosing the musculoskeletal system or teeth
- A61B5/4519—Muscles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2560/00—Constructional details of operational features of apparatus; Accessories for medical measuring apparatus
- A61B2560/02—Operational features
- A61B2560/0242—Operational features adapted to measure environmental factors, e.g. temperature, pollution
- A61B2560/0247—Operational features adapted to measure environmental factors, e.g. temperature, pollution for compensation or correction of the measured physiological value
- A61B2560/0252—Operational features adapted to measure environmental factors, e.g. temperature, pollution for compensation or correction of the measured physiological value using ambient temperature
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
- A61B2562/02—Details of sensors specially adapted for in-vivo measurements
- A61B2562/0271—Thermal or temperature sensors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
- A61B5/024—Detecting, measuring or recording pulse rate or heart rate
- A61B5/02416—Detecting, measuring or recording pulse rate or heart rate using photoplethysmograph signals, e.g. generated by infrared radiation
Abstract
A measuring device (1, 2, 3, 71), a measuring method and an electronic device (7) for measuring the energy consumption of an individual. The measuring device (1, 2, 3, 71) comprises: a near infrared unit (10) for emitting near infrared rays into muscle tissue of the individual for determining a muscle oxygenation value of the individual by reflection of the muscle tissue for the near infrared rays; an electrode array (20) for measuring the electrical conductivity of the individual's skin; and a control unit (30) operatively connected to the near infrared unit (10) and the electrode array (20) to control activation of the near infrared unit (10) and the electrode array (20) and to acquire a muscle oxygenation value and an electrical conductivity, so as to determine the energy expenditure of the individual based on the muscle oxygenation value and the electrical conductivity and the skin temperature and the ambient temperature of the individual. The measuring device (1, 2, 3, 71), the measuring method and the electronic device (7) for measuring the energy consumption of an individual are at least capable of measuring both dynamic and static energy consumption.
Description
Technical Field
The present application relates to the field of sports health, and more particularly to a measuring device, a measuring method and an electronic device for measuring energy expenditure of an individual.
Background
In the field of exercise health, measuring an individual's energy expenditure is very important for an individual's energy balance, especially for individuals affected by metabolic-related chronic diseases (e.g., diabetes, cardiovascular diseases, etc.). In the prior art, measuring devices comprising activity sensors, such as acceleration sensors, are often used to measure the energy expenditure of an individual; these activity sensors are generally not capable of measuring resting energy expenditure which accounts for more than 80% of the total energy expenditure of the body.
Therefore, it is desirable to have a device that is capable of measuring energy consumption including resting energy consumption.
Disclosure of Invention
The following presents a simplified summary of the application in order to provide a basic understanding of some aspects of the application. It should be understood that this summary is not an exhaustive overview of the present application. It is not intended to identify key or critical elements of the application or to delineate the scope of the application. Its sole purpose is to present some concepts in a simplified form as a prelude to the more detailed description that is discussed later.
In view of the above-mentioned drawbacks of the prior art, it is an object of the present application to provide a measuring device, a measuring method and an electronic device for measuring the energy consumption of an individual, which overcome at least the drawbacks of the prior art.
An embodiment of the present application provides a measurement apparatus, including: a near infrared unit for emitting near infrared rays into muscle tissue of an individual to determine a muscle oxygenation value of the individual by reflection of the near infrared rays by the muscle tissue; an electrode array for measuring the electrical conductivity of the individual's skin; and a control unit operatively connected to the near-infrared unit and the electrode array to control activation of the near-infrared unit and the electrode array and to acquire the muscle oxygenation value and the electrical conductivity so as to determine the energy expenditure of the individual based on the muscle oxygenation value and the electrical conductivity and the skin temperature and the ambient temperature of the individual.
Another embodiment of the present application provides a method for measuring energy expenditure of an individual, comprising: emitting near infrared into muscle tissue of the individual to determine a muscle oxygenation value of the muscle tissue by reflection of the infrared by the muscle tissue; measuring the electrical conductivity of the individual's skin; and obtaining the muscle oxygenation value and the electrical conductivity to determine an energy expenditure of the individual based on the muscle oxygenation value and the electrical conductivity and a skin temperature and an ambient temperature of the individual.
Yet another embodiment of the present application provides an electronic device for measuring energy consumption of an individual comprising: a measurement device and an electronic device capable of communicating with the measurement device. The measuring device includes: a near infrared unit for emitting near infrared rays into muscle tissue of the individual to determine a muscle oxygenation value of the muscle tissue by reflection of the infrared rays by the muscle tissue; an electrode array for measuring the electrical conductivity of the individual's skin; and a control unit operatively connected to the near infrared unit and the electrode array to control activation of the near infrared unit and the electrode array and to acquire and transmit the muscle oxygenation values and the electrical conductivity. The electronic device receives the muscle oxygenation value and the electrical conductivity from a control unit of the measurement device and determines an energy expenditure of the individual based on the muscle oxygenation value and the electrical conductivity and a skin temperature and an ambient temperature of the individual.
The measuring device and the measuring method for measuring the energy consumption of an individual and the electronic device according to the application have at least one of the following advantages: being able to measure both dynamic and static energy consumption; the ability to measure energy consumption in a non-invasive manner; being convenient for dress on one's body, can realizing the real-time measurement to energy consumption.
Drawings
One or more embodiments are illustrated by way of example in the accompanying drawings, which correspond to the figures in which like reference numerals refer to similar elements and which are not to scale unless otherwise specified.
Fig. 1 is a block diagram showing an exemplary structure of a measuring apparatus according to a first embodiment of the present application.
Fig. 2 is a block diagram showing an exemplary structure of a measuring apparatus according to a second embodiment of the present application.
Fig. 3 is a block diagram schematically showing an example structure of a near-infrared unit according to the first and second embodiments of the present application.
Fig. 4 is a graph showing the relationship between the extinction coefficient of oxyhemoglobin and anaerobic hemoglobin for near infrared rays and the wavelength of near infrared rays.
Fig. 5 shows an exemplary block diagram of a measuring device according to a third embodiment of the present application.
Fig. 6 is a flowchart illustrating an exemplary process of a measurement method according to an embodiment of the present application.
Fig. 7 is a block diagram illustrating an exemplary structure of an electronic device according to an embodiment of the present application.
Detailed Description
In order to make the objects, technical solutions and advantages of the present application more apparent, some embodiments of the present application will be described in detail below with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are merely illustrative of the present application and are not intended to limit the present application.
In the field of exercise health, it is desirable to be able to conveniently acquire energy consumption of an individual in various activity states, so as to realize judgment and tracking of human health conditions based on the energy consumption. Therefore, there is a need in the art for a measuring device capable of measuring energy expenditure in various activity states, in particular for facilitating mounting on a body part of an individual, such as an arm or leg of a human body.
Fig. 1 is a block diagram showing an exemplary structure of a measuring apparatus according to a first embodiment of the present application. As shown in fig. 1, the measuring apparatus 1 includes: a near infrared unit 10 for emitting near infrared rays into muscle tissue of an individual to determine a muscle oxygenation value of the muscle tissue by reflection of the muscle tissue for the near infrared rays; an electrode array 20 for measuring the electrical conductivity of the individual's skin; and a control unit 30 operatively connected to the near infrared unit 10 and the electrode array 20 to control the activation of the near infrared unit 10 and the electrode array 30 and to acquire the muscle oxygenation value and the electrical conductivity in order to determine the energy expenditure of the individual based on the muscle oxygenation value and the electrical conductivity and the skin temperature and the ambient temperature of the individual.
According to the present application, an individual as a measurement target of a measurement apparatus may be, for example, a living body such as a human body or an animal body. The above-described measuring device 1 according to the first embodiment of the present application is conveniently fitted on a body part of an individual, such as an arm or a leg, so as to enable measurement of the energy expenditure of the individual by measuring the muscle oxygenation value of the body part and enabling measurement of the electrical conductivity of the skin at the body part. For example, the mounting of the measuring device on an appropriate body part of the individual may be selected according to the type of sport the individual is engaged in, for example the measuring device may be mounted at a body part of the individual is primarily using for exercising. However, the present disclosure is not limited thereto, and those skilled in the art will appreciate that the specific installation location of the measuring device may be determined according to actual needs. For example, if the individual is running, the measuring device may be mounted on the individual's leg, arm or other location.
The near infrared unit 10 of the above-described measurement apparatus 1 according to the first embodiment of the present application may evaluate the muscle oxygenation values of the individual during various states including a resting state and a moving state, for example, using near infrared spectroscopy (NIRS). The use of NIRS to determine muscle oxygenation values of an individual is performed in a non-invasive manner.
Since near infrared rays can relatively easily pass through muscle tissue of a human body and oxygenated hemoglobin and non-oxygenated hemoglobin used for determining a muscle oxygenation value have different absorptances for near infrared rays in different wavelength ranges, based on this, the near infrared unit 10 can determine a muscle oxygenation value of an individual by emitting near infrared rays to muscle tissue of the individual and by reflection of the near infrared rays by the muscle tissue.
According to the first embodiment of the present application, the electrode array 20 is used for measuring the electrical conductivity of the skin of the individual, and the electrode array 20 can implement the measurement of the electrical conductivity of the skin in any manner known in the art, and the detailed description thereof is omitted here. For example, the electrode array according to the first embodiment of the present application may be implemented using a muscle electromyogram sensor array, but the present application is not limited thereto, and any other form of electrode array may be used to implement the electrode array in the measurement apparatus according to the present application as long as the measurement of the electrical conductivity of the skin can be achieved.
In a first embodiment of the present application, the control unit 30 is operatively connected to the near infrared unit 10 and the electrode array 20 for controlling the activation of the near infrared unit 10 and the electrode array 20 and receiving muscle oxygenation values and electrical conductivities from the near infrared unit 10 and the electrode array 20. The control unit 30 may be implemented using a combinational logic controller in the prior art. The present disclosure is not limited thereto, and the control unit 30 may also be implemented using, for example, a micro-program controller (e.g., CPU).
According to an embodiment of the present application, the control unit 30 may be configured to control the near-infrared unit 10 and the electrode array 20 to periodically activate the near-infrared unit and the electrode array.
According to the application, the control unit 30, after obtaining the muscle oxygenation value and the skin conductivity of the individual, may send the muscle oxygenation value and the conductivity to an external device, e.g. a mobile terminal, so that the external device calculates the energy consumption of the individual based on the muscle oxygenation value and the skin conductivity and the skin temperature and the ambient temperature of the individual. However, the present disclosure is not limited thereto, and for example, in the case where the control unit 30 is implemented by a controller having an arithmetic function, an operation of calculating the energy expenditure of the individual based on the muscle oxygenation value and the electrical conductivity of the skin, and the skin temperature and the ambient temperature of the individual may also be performed by the control unit 30.
According to the application, the skin temperature and the ambient temperature of the individual may be obtained by the control unit by communication with a temperature sensor, e.g. located outside the measuring device, or the measuring device may also comprise a temperature sensor to measure the skin temperature and the ambient temperature of the individual.
Fig. 2 is a block diagram showing an exemplary structure of a measuring apparatus according to a second embodiment of the present application.
As shown in fig. 2, in addition to including the near-infrared unit 10, the electrode array 20, and the control unit 30 similarly to the measurement apparatus 1 of fig. 1, the measurement apparatus 2 may further include: an ambient temperature sensor 40 operatively connected to the control unit 30, the ambient temperature sensor 40 being configured to measure an ambient temperature and to send the ambient temperature to the control unit 30; and a skin temperature sensor 50 operatively connected to the control unit 30, the skin temperature sensor 50 being configured to measure a skin temperature of the individual and to send the measured skin temperature to the control unit 30.
The measuring device 2 according to the second embodiment of the present application can use any existing ambient temperature sensor and skin temperature sensor to measure the ambient temperature and the skin temperature, and the specific measuring method thereof is not described herein again.
The control unit 30 of the measurement apparatus 2 according to the second embodiment of the present application may also be configured to control the ambient temperature sensor 40 and the skin temperature sensor 50 to activate the ambient temperature sensor 40 and the skin temperature sensor 50, for example, the control unit 30 may periodically control to activate the ambient temperature sensor 40 and the skin temperature sensor 50.
Fig. 3 is a block diagram schematically showing an example structure of the near-infrared unit 10 according to the first and second embodiments of the present application.
As shown in fig. 3, the near-infrared unit 10 includes: a near infrared ray emitter 101 for emitting a plurality of sets of near infrared rays having different wavelengths to muscle tissues of an individual, respectively; a near-infrared receiver 102 for receiving reflected light of each of the groups of near-infrared rays reflected from the muscle tissue; and a processing module 103 for determining a hemoglobin value and a myoglobin value of the individual from the sets of reflected light received by the near infrared receiver and determining a muscle oxygenation value of the muscle tissue based on the hemoglobin value and the myoglobin value.
According to the present application, the near infrared ray emitter 101 may be, for example, an LED lamp capable of emitting near infrared rays, but the present application is not limited thereto, and those skilled in the art will appreciate that the near infrared ray emitter 101 according to the present application may also be other emitters capable of emitting near infrared rays. According to the present application, the near infrared ray receiver 102 may be realized by, for example, a photodiode.
According to the present application, the processing module 103 may be further configured to determine, for each set of near infrared rays, attenuation values of the near infrared rays from the emission current of the near infrared ray emitter 101 and the reception current of the near infrared ray receiver 101, and determine oxygenated hemoglobin and deoxygenated hemoglobin of the muscle tissue based on the attenuation values of the sets of near infrared rays, thereby determining a muscle oxygenation value of the individual from the determined oxygenated hemoglobin and deoxygenated hemoglobin.
According to one embodiment of the present application, the processing module 30 may determine the oxygenated hemoglobin value and the deoxygenated hemoglobin value according to, for example, lambert-beer's law, and more particularly may determine the oxygenated hemoglobin value and the deoxygenated hemoglobin value using, for example, the following equation (1):
wherein A is an attenuation value of near infrared rays after being incident on muscle tissue, I0Is the input light intensity, I is the reflected light intensity, C0+C1λ is attenuation other than hemoglobin and water, L is distance of near infrared rays from the transmitting end to the receiving end (for example, the near infrared receiver 102 may be disposed in a range of 10mm to 20mm apart from the near infrared transmitter 101), Chhb、ChboRespectively an anaerobic hemoglobin density (also called anaerobic hemoglobin value) and an aerobic hemoglobin density (also called aerobic hemoglobin value), εhhb、εhboThe extinction coefficients of oxygen-free hemoglobin and oxygen-free hemoglobin, respectively, to near infrared rays.
The near infrared unit 10 may be based on, for example, emitting near infrared raysReflected current I formed by emission current of LED lamp and reflected light received by near infrared receiverPDThe attenuation value A of the near infrared ray is calculated. However, the present disclosure is not limited thereto, and the attenuation value a of the near infrared ray may be calculated by other methods known in the art.
FIG. 4 is a graph showing extinction coefficients ε of aerobic hemoglobin and anaerobic hemoglobin with respect to near infrared rayshbo、εhhbAnd a graph of the relationship with the wavelength of the near infrared ray. That is, the extinction coefficient ε of the aerobic hemoglobin and the anaerobic hemoglobin with respect to the near infrared ray can be determined by the wavelength of the near infrared ray emitted from the near infrared ray emitter 101hbo、εhhb。
The processing module 130 can obtain the anaerobic hemoglobin density C by solving the optimal value based on the above equation (1) by a nonlinear optimization method according to the attenuation of at least four different wavelengthshhbAnd aerobic hemoglobin density Chbo。
After obtaining the aerobic hemoglobin density and the anaerobic hemoglobin density, processing module 130 may calculate a muscle oxygenation value based on the aerobic hemoglobin density and the anaerobic hemoglobin density, e.g., processing module 130 may calculate a muscle oxygenation value S according to, e.g., equation (2) belowmO2：
Wherein C ishhbIs anaerobic hemoglobin density, ChboThe aerobic hemoglobin density.
According to the present disclosure, the near infrared ray emitter 101 of the near infrared unit 10 is preferably configured to emit near infrared rays having wavelengths of 660nm, 730nm, 810, 850nm, and 940 nm.
According to another embodiment of the application, the processing module 130 may determine a hemoglobin value and a myoglobin value of the individual from a plurality of sets of said reflected light received by the near infrared receiver 102 and determine a muscle oxygenation value of the muscle tissue based on the hemoglobin value and the myoglobin value. Such asThe processing module 130 may calculate the muscle oxygenation value S by equation (3)mO2:
SmO2＝Δ(Chbo+O2Mb–(Chhb+HMb)) (3)
Wherein, ChhbIs anaerobic hemoglobin density, ChboIs aerobic hemoglobin density, O2Mb is the aerobic myoglobin density and HMb is the anaerobic myoglobin density.
Aerobic myoglobin Density O2Mb and anaerobic myoglobin density HMb can be obtained, for example, from aerobic hemoglobin density and anaerobic hemoglobin density using any method known in the art. The specific manner of obtaining it is well known in the art and will not be described herein.
According to an embodiment of the application, the control unit 30 may be further configured to calculate a radiant heat quantity radiated to the outside by the individual upon oxygen consumption from the electrical conductivity of the skin acquired from the electrode array 20, the difference between the skin surface temperature of the individual and the ambient temperature, and to determine the cardiac output of the individual based on the radiant heat quantity, the heart rate of the individual and the muscle oxygenation value, thereby determining the oxygen consumption of the individual from the cardiac output and muscle oxygenation values of the individual. The individual's skin surface temperature and ambient temperature may be obtained by communicating with an external device located outside the measurement device, or in the case where the measurement device includes a skin temperature sensor 50 and an ambient temperature sensor 40, such as the measurement device 2 shown in fig. 2, the individual's skin temperature and ambient temperature may be obtained from the skin temperature sensor 50 and the ambient temperature sensor 40, respectively.
The control unit 30 may, for example, calculate the amount of heat radiated by the individual to the outside when oxygen is consumed from the electrical conductivity measured by the electrode array 20, the difference between the skin surface temperature and the ambient temperature, and the area of the individual's surface skin. The area of the individual's surface skin can be obtained from the individual's height and weight using any method known in the art.
The heat H radiated to the environment by an individual during oxygen consumption is related to the individual's cardiac output, the heart rate, and the oxygen content introduced into the tissue by the blood (i.e., muscle oxygenation), and the cardiac output is generally related toCan be calculated from cardiac output and heart rate, and can be calculated according to caloric value H, heart rate HR and muscle oxygenation value S radiated to the outside during oxygen consumptionmO2To determine the cardiac output Q. For example, the cardiac output SV for determining the final oxygen consumption amount may be determined according to the following formula (4), and determined according to the following formula (5):
SV＝H/CXHRXSmO2 (4)
Q＝SVXHR (5)
where H is the amount of heat radiated by the body to the outside upon consumption of oxygen, which can be determined from the electrical conductivity measured by the electrode array 20, the difference between the skin surface temperature and the ambient temperature, and the area of the surface skin of the individual, as described above. Parameter C is a parameter that reflects the characteristics of different individuals, and can be determined according to the gender, height, weight, and age of the individual; those skilled in the art will appreciate that the parameter C may be determined in advance according to various methods, such as generating a database of appropriate values based on a particular parameter, by using previously determined value-worthy approximations and/or extrapolation.
Furthermore, the heart rate of the individual for determining the cardiac output Q may be obtained from an external device other than the measurement device by the control unit 30 communicating with the external device. The present disclosure is not limited thereto, for example, the heart rate of the individual may also be obtained by letting the measuring device comprise a heart rate measuring unit.
Fig. 5 shows an exemplary block diagram of a measuring device according to a third embodiment of the present application. As shown in fig. 5, the measuring apparatus 3 includes, in addition to the near-infrared unit 10, the electrode array 20, the control unit 30, the ambient temperature sensor 40, and the skin temperature sensor 50 similarly to the measuring apparatus 2 of fig. 2: a heart rate measurement unit 60 operatively connected to the control unit 30, the heart rate measurement unit 60 being configured to measure the heart rate of the individual and to send the measured heart rate to the control unit 30. The heart rate measuring unit 60 may measure the heart rate of the individual by any method in the prior art, and the detailed measurement method is not described herein.
Muscle oxygenation values S are obtained at the control unit 30 from the near infrared unit 10mO2And having determined the cardiac output Q, the control unit 30 may be based on the muscle oxygenation value SmO2And cardiac output Q further determines oxygen consumption VO2. For example, the control unit 30 may determine the oxygen consumption VO according to the following equation (6) based on the fick equation2。
VO2＝Q×(97-SmO2)/100×1.34×Chhb×10(6)
Wherein, ChhbThe oxygenated hemoglobin value of the individual, which can be determined, for example, at the near infrared unit 10, the muscle oxygenation value SmO2Is obtained when the compound is used.
The control unit 30, after determining the oxygen consumption amount, may further calculate a calorie consumption amount in the process of consuming oxygen based on the oxygen consumption amount and the weight of the individual. Any method known in the art may be used to determine the calorie consumption based on the oxygen consumption. For example, the calorie consumption amount E may be calculated based on the oxygen consumption amount using the following formula (7).
E＝VO2×W×K (7)
Wherein, VO2Oxygen consumption by an individual; w is the weight of the individual; k is a constant which can be set by the person skilled in the art as a function of the circumstances and can be set, for example, to 5.
The manner of determining the calorie consumption amount based on the oxygen consumption amount is exemplarily illustrated above, but the present application is not limited thereto, and those skilled in the art can understand that other methods of determining the calorie consumption amount based on the oxygen consumption amount in the prior art may also be employed to determine the calorie consumption amount.
The above embodiment describes that in the case where the control unit 30 is implemented by a controller having an arithmetic function, the oxygen consumption, and thus the calorie consumption, is determined by the control unit based on the muscle oxygenation value and the electrical conductivity of the skin of the individual. However, the present disclosure is not limited thereto, and the person skilled in the art will appreciate that the operation of determining the oxygen consumption based on the muscle oxygenation value and the electrical conductivity of the skin of the individual may also be implemented by the processing module 103 of the near infrared unit 10. Alternatively, the operation of determining the oxygen consumption, and thus the calorie consumption, based on the muscle oxygenation value and the electrical conductivity of the skin of the individual may also be performed by an external device (e.g., a mobile terminal). The processing module 103 of the near-infrared unit 10 and the external device perform the above determination operation similarly to the operation of the control unit 30 determining the oxygen consumption and thus the calorie consumption based on the muscle oxygenation value and the skin conductivity of the individual, and thus are not described again.
According to the present application, there is also provided a measurement method for measuring energy expenditure of an individual. An exemplary process of the measurement method is described below in conjunction with fig. 6.
As shown in fig. 6, a measurement method according to an embodiment of the present application includes: emitting near infrared rays into muscle tissue of the individual to determine a muscle oxygenation value of the muscle tissue by reflection of the infrared rays by the muscle tissue in step S1; in step S2, the electrical conductivity of the individual' S skin is measured; and in step S3, determining an energy expenditure of the individual based on the muscle oxygenation value and the electrical conductivity and the skin temperature and the ambient temperature of the individual. For example, steps S1, S2, S3 may be respectively implemented by performing operations of the near infrared unit 10, the electrode array 20, and the control unit, for example, described with reference to fig. 1, and a detailed description thereof is omitted herein.
According to the present application, there is also provided an electronic device for measuring energy consumption of an individual.
Fig. 7 shows an exemplary structural block diagram of an electronic device according to an embodiment of the present application. As shown in fig. 7, the electronic apparatus includes: a measuring device 71 for measuring muscle oxygenation values and skin conductivity of the individual; and electronics 72 receiving the muscle oxygenation values and the electrical conductivity from the measurement means 71 and determining the energy expenditure of the individual based on the muscle oxygenation values and the electrical conductivity.
The measurement device 71 according to the present disclosure may be the measurement device described with reference to fig. 1-4. As shown in fig. 7, the measuring device 71 includes: a near infrared unit 711 for emitting near infrared rays into muscle tissue of the individual to determine a muscle oxygenation value of the muscle tissue by reflection of the infrared rays by the muscle tissue; an electrode array 712 for measuring the electrical conductivity of the individual's skin; and a control unit 713 operatively connected to the near infrared emitter and the electrode array to control activation of the near infrared emitter and the electrode array and to acquire and send muscle oxygenation values and electrical conductivity to the electronics 72.
The measuring device and the measuring method for measuring the energy consumption of an individual and the electronic device according to the application have at least one of the following advantages compared to the prior art: being able to measure both dynamic and static energy consumption; the ability to measure energy consumption in a non-invasive manner; being convenient for dress on one's body, can realizing the real-time measurement to energy consumption.
Finally, it is also noted that, in the present disclosure, relational terms such as first and second, and the like are used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions. Also, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus. Without further limitation, an element defined by the phrase "comprising an … …" does not exclude the presence of other identical elements in a process, method, article, or apparatus that comprises the element.
While the disclosure has been disclosed by the description of certain embodiments thereof, it will be appreciated that those skilled in the art will be able to devise various modifications, improvements, or equivalents of the disclosure within the spirit and scope of the appended claims. Such modifications, improvements and equivalents are intended to be included within the scope of the present disclosure as claimed.
Claims (11)
1. A measurement device, the measurement device comprising:
a near infrared unit for emitting near infrared rays into muscle tissue of an individual to determine a muscle oxygenation value of the individual by reflection of the near infrared rays by the muscle tissue;
an electrode array for measuring the electrical conductivity of the individual's skin; and
a control unit operatively connected to the near-infrared unit and the electrode array to control activation of the near-infrared unit and the electrode array and to acquire the muscle oxygenation values and the electrical conductivity;
the control unit is further configured to calculate a radiant heat quantity radiated by the individual to the outside upon consumption of oxygen from the electrical conductivity and a difference between a skin surface temperature of the individual and an ambient temperature, and to determine a cardiac output quantity of the individual based on the radiant heat quantity, a heart rate of the individual and the muscle oxygenation value, thereby determining an oxygen consumption quantity of the individual from the cardiac output quantity and the muscle oxygenation value of the individual; wherein, the related calculation formula is as follows: SV = H/CXHRXSmO2Q = SVXHR, wherein SV is cardiac output, H is the caloric content of the individual radiating to the outside during oxygen consumption, C is a parameter reflecting the characteristics of different individuals and determined according to the sex, height, weight and age of the individual, HR is heart rate, SmO2Is muscle oxygenation value, Q is cardiac output;
the control unit is further configured to determine an energy expenditure of the individual from the oxygen consumption of the individual.
2. The measurement device of claim 1, further comprising:
an ambient temperature sensor operatively connected to the control unit, the ambient temperature sensor configured to measure an ambient temperature and send the ambient temperature to the control unit; and
a skin temperature sensor operatively connected to the control unit, the skin temperature sensor configured to measure a skin temperature of the individual and to send the skin temperature to the control unit.
3. The measurement device according to claim 1 or 2, wherein the near-infrared unit includes:
a near infrared ray emitter for emitting a plurality of sets of near infrared rays having different wavelengths to the muscle tissue of the individual, respectively;
a near-infrared receiver for receiving reflected light of each of the plurality of groups of near-infrared rays reflected from the muscle tissue; and
a processing module to determine hemoglobin values of the individual from the sets of reflected light received by the near infrared receiver and to determine muscle oxygenation values of the muscle tissue based on the hemoglobin values.
4. The measurement device of claim 3, wherein the processing module is configured to determine, for each set of near infrared rays, attenuation values of the near infrared rays as a function of an emission current of the near infrared ray emitter and a reception current of the near infrared ray receiver, and to determine oxygenated hemoglobin values and deoxygenated hemoglobin values of the muscle tissue based on a plurality of sets of the attenuation values of the near infrared rays, thereby determining muscle oxygenation values of the muscle tissue as a function of the determined oxygenated hemoglobin values and deoxygenated hemoglobin values.
5. The measurement device according to claim 4, wherein the near infrared ray emitter emits five groups of near infrared rays having wavelengths of 660nm, 730nm, 810nm, 850nm, and 940nm, respectively, to the muscle tissue so as to determine a muscle oxygenation value of the muscle tissue based on reflections of at least four groups of the five groups of near infrared rays.
6. The measurement device of claim 1, further comprising:
a heart rate measurement unit operatively connected to the control unit, the heart rate measurement unit configured to measure a heart rate of the individual and to send the measured heart rate to the control unit.
7. The measurement device according to claim 1 or 6, wherein the control unit is further configured to determine the calorie consumption of the individual based on the oxygen consumption of the individual.
8. The measurement device according to claim 1, wherein the control unit is configured to control the near-infrared unit and the electrode array to periodically activate the near-infrared unit and the electrode array.
9. A method for measuring energy expenditure of an individual, comprising:
emitting near infrared into muscle tissue of the individual to determine a muscle oxygenation value of the muscle tissue by reflection of the infrared by the muscle tissue;
measuring the electrical conductivity of the individual's skin; and
obtaining the muscle oxygenation value and the electrical conductivity to calculate a radiant heat radiated by the individual to the outside as oxygen is consumed based on the electrical conductivity and a difference between a skin surface temperature of the individual and an ambient temperature; and determining the cardiac output of the individual based on the radiant heat, the heart rate of the individual and the muscle oxygenation values, thereby determining the oxygen consumption of the individual from the cardiac output and the muscle oxygenation values of the individual; determining an energy expenditure of the individual from the oxygen consumption of the individual; wherein, the related calculation formula is as follows: SV = H/CXHRXSmO2Q = SVXHR, wherein SV is cardiac output, H is the caloric content of the individual radiating to the outside during oxygen consumption, C is a parameter reflecting the characteristics of different individuals and determined according to the sex, height, weight and age of the individual, HR is heart rate, SmO2Is the muscle oxygenation value and Q is the cardiac output.
10. An electronic device for measuring energy consumption of an individual, comprising:
a measurement device, the measurement device comprising:
a near infrared unit for emitting near infrared rays into muscle tissue of the individual to determine a muscle oxygenation value of the muscle tissue by reflection of the infrared rays by the muscle tissue;
an electrode array for measuring the electrical conductivity of the individual's skin; and
a control unit operatively connected to the near infrared unit and the electrode array to control activation of the near infrared unit and the electrode array and to acquire and transmit the muscle oxygenation values and the electrical conductivity; and
electronic means for receiving the muscle oxygenation values and the electrical conductivity from a control unit of the measuring means and calculating a radiant heat radiated by the individual to the outside upon oxygen consumption based on the electrical conductivity and a difference between a skin surface temperature of the individual and an ambient temperature; and determining the cardiac output of the individual based on the radiant heat, the heart rate of the individual and the muscle oxygenation values, thereby determining the oxygen consumption of the individual from the cardiac output and the muscle oxygenation values of the individual; determining an energy expenditure of the individual from the oxygen consumption of the individual; wherein, the related calculation formula is as follows: SV = H/CXHRXSmO2Q = SVXHR, wherein SV is cardiac output, H is the caloric content of the individual radiating to the outside during oxygen consumption, C is a parameter reflecting the characteristics of different individuals and determined according to the sex, height, weight and age of the individual, HR is heart rate, SmO2Is the muscle oxygenation value and Q is the cardiac output.
11. The electronic device of claim 10, wherein the electronic device is a mobile device.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662346723P | 2016-06-07 | 2016-06-07 | |
| US62/346,723 | 2016-06-07 | ||
| PCT/CN2017/070338 WO2017211081A1 (en) | 2016-06-07 | 2017-01-05 | Measurement apparatus for measuring power consumption of individual, measurement method and electronic device |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN108289646A CN108289646A (en) | 2018-07-17 |
| CN108289646B true CN108289646B (en) | 2021-07-06 |
Family
ID=60578327
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201780000137.9A Active CN108289646B (en) | 2016-06-07 | 2017-01-05 | Measuring device, measuring method and electronic equipment for measuring individual energy consumption |
Country Status (3)
| Country | Link |
|---|---|
| US (1) | US20210045654A1 (en) |
| CN (1) | CN108289646B (en) |
| WO (1) | WO2017211081A1 (en) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109041476A (en) * | 2018-08-08 | 2018-12-18 | 加动健康科技（芜湖）有限公司 | Set casing for individual energy consumption measuring device |
| CN109011512A (en) * | 2018-08-08 | 2018-12-18 | 加动健康科技（芜湖）有限公司 | Individual energy consumption measurement equipment with flesh patch |
| CN109011514A (en) * | 2018-08-08 | 2018-12-18 | 加动健康科技（芜湖）有限公司 | The individual energy consumption measurement equipment shown with body |
| CN108990353A (en) * | 2018-08-08 | 2018-12-11 | 加动健康科技（芜湖）有限公司 | Set casing for individual energy consumption measuring device |
| CN109124631A (en) * | 2018-08-08 | 2019-01-04 | 加动健康科技（芜湖）有限公司 | Charge the individual energy consumption measurement equipment of pole piece |
| CN109041475A (en) * | 2018-08-08 | 2018-12-18 | 加动健康科技（芜湖）有限公司 | Set casing for individual energy consumption measuring device |
| CN109011510A (en) * | 2018-08-08 | 2018-12-18 | 加动健康科技（芜湖）有限公司 | Individual energy consumption measurement equipment with lens mechanism |
| CN109222989A (en) * | 2018-08-08 | 2019-01-18 | 加动健康科技（芜湖）有限公司 | The near-infrared unit of flesh oxygen measurement |
| CN109124630A (en) * | 2018-08-08 | 2019-01-04 | 加动健康科技（芜湖）有限公司 | Walking test macro |
| CN109692000A (en) * | 2018-12-10 | 2019-04-30 | 中国人民解放军总医院 | Portable V O2 detection device |
| CN115177214A (en) * | 2022-08-10 | 2022-10-14 | 中国科学院深圳先进技术研究院 | System for detecting coupling function of motor nerve, muscle and blood vessel |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101801261A (en) * | 2007-07-13 | 2010-08-11 | 马萨诸塞大学 | Physical performance monitoring and monitors |
| CN103735274A (en) * | 2013-12-25 | 2014-04-23 | 电子科技大学 | Device and method for detecting absolute amount of blood oxygen and blood volume of local brain tissue |
| CN104586407A (en) * | 2014-01-16 | 2015-05-06 | 清华大学 | Multi-parameter physiological indication detection device and detection method thereof |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20070276210A1 (en) * | 2003-11-14 | 2007-11-29 | Guillermo Gutierrez | Apparatus and method for measuring myocardial oxygen consumption |
| US20070021678A1 (en) * | 2005-07-19 | 2007-01-25 | Cardiac Pacemakers, Inc. | Methods and apparatus for monitoring physiological responses to steady state activity |
| WO2007140422A2 (en) * | 2006-05-30 | 2007-12-06 | University Of Massachusetts | Measuring tissue oxygenation |
| US20140249432A1 (en) * | 2010-12-28 | 2014-09-04 | Matt Banet | Body-worn system for continuous, noninvasive measurement of cardiac output, stroke volume, cardiac power, and blood pressure |
| CN103648370B (en) * | 2011-07-08 | 2017-03-29 | 生命Q全球有限公司 | Individualized nutrition and health care adminicle |
| US20130281796A1 (en) * | 2012-04-20 | 2013-10-24 | Broadmaster Biotech Corp. | Biosensor with exercise amount measuring function and remote medical system thereof |
| CN103610468A (en) * | 2013-12-05 | 2014-03-05 | 深圳市奥博莱特科技有限公司 | Blood oxygen blood volume absolute amount detection device and method thereof |
| WO2015189687A1 (en) * | 2014-06-13 | 2015-12-17 | Shankar Bhairav | An integrated device to calcutate heart rate and body activity accurately |
-
2017
- 2017-01-05 US US16/098,540 patent/US20210045654A1/en not_active Abandoned
- 2017-01-05 CN CN201780000137.9A patent/CN108289646B/en active Active
- 2017-01-05 WO PCT/CN2017/070338 patent/WO2017211081A1/en active Application Filing
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101801261A (en) * | 2007-07-13 | 2010-08-11 | 马萨诸塞大学 | Physical performance monitoring and monitors |
| CN103735274A (en) * | 2013-12-25 | 2014-04-23 | 电子科技大学 | Device and method for detecting absolute amount of blood oxygen and blood volume of local brain tissue |
| CN104586407A (en) * | 2014-01-16 | 2015-05-06 | 清华大学 | Multi-parameter physiological indication detection device and detection method thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| US20210045654A1 (en) | 2021-02-18 |
| CN108289646A (en) | 2018-07-17 |
| WO2017211081A1 (en) | 2017-12-14 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN108289646B (en) | Measuring device, measuring method and electronic equipment for measuring individual energy consumption | |
| US8043227B2 (en) | Non-invasive system and method for measuring skin hydration of a subject | |
| US11291374B2 (en) | Apparatus and method for estimating bio-information | |
| CN101489482B (en) | Measuring tissue oxygenation | |
| EP0613652B1 (en) | Apparatus and method for non-invasive measurement of oxygen saturation | |
| JP3566277B1 (en) | Blood glucose meter | |
| US9451887B2 (en) | Systems and methods for measuring electromechanical delay of the heart | |
| JP5602629B2 (en) | Diagnostic sensor unit | |
| US20140323879A1 (en) | Systems, devices and methods for monitoring hemodynamics | |
| US10226183B2 (en) | Devices and methods for temperature determination | |
| NL2002852C2 (en) | EAR SENSOR SYSTEM FOR NON INVASIVE MEASUREMENT OF METHODS. | |
| KR20180015171A (en) | Device and method for determining biological indicator levels of tissue | |
| JP2016537069A (en) | Photophysiological sensor and assembly method | |
| JP2010534083A (en) | Tissue oxygen measuring device and method | |
| JP2017023820A (en) | Non-invasive measurement of blood oxygen saturation | |
| EP2922462A1 (en) | Device and method for extracting physiological information | |
| WO2011041090A1 (en) | Systems and methods for normalizing a plethysmograph signal for improved feature analysis | |
| WO2012135079A1 (en) | Systems and methods for measuring oxygenation | |
| US20170303788A1 (en) | Wearable device for tissue monitoring with effective ambient light blocking | |
| EP4138662B1 (en) | Sensor characterization through forward voltage measurements | |
| JP6043276B2 (en) | Scattering absorber measuring apparatus and scattering absorber measuring method | |
| US20180317825A1 (en) | Device and method for measuring the concentration of a chemical compound in blood | |
| JP2019528954A (en) | Optical vital sign sensor | |
| JP2017047176A (en) | Pulse photometer, and reliability evaluation method for calculated value on light-absorbing substance concentration in blood | |
| KR101867902B1 (en) | System and method for measuring subcutaneous fat thickness using the deviation of the absorption peak wavelength of fat and water |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CP01 | Change in the name or title of a patent holder | ||
| CP01 | Change in the name or title of a patent holder |
Address after: 241003 9th floor, building 4, phase II, service outsourcing park, high tech Zone, Wuhu City, Anhui Province Patentee after: GETWELL HEALTH TECHNOLOGY (WUHU) Co.,Ltd. Patentee after: Jiadong Technology (Shenzhen) Co.,Ltd. Address before: 241003 9th floor, building 4, phase II, service outsourcing park, high tech Zone, Wuhu City, Anhui Province Patentee before: GETWELL HEALTH TECHNOLOGY (WUHU) Co.,Ltd. Patentee before: GETWELL EXERCISE & HEALTH TECHNOLOGY (SHENZHEN) Co.,Ltd. |
|
| TR01 | Transfer of patent right | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20211228 Address after: 518067 Floor 9, 601, zhuofeigoo building (Haixiang Plaza), No. 1052, Nanhai Avenue, Huaguoshan community, merchants street, Nanshan District, Shenzhen, Guangdong Patentee after: Jiadong medical (Shenzhen) Co.,Ltd. Address before: 241003 9th floor, building 4, phase II, service outsourcing park, high tech Zone, Wuhu City, Anhui Province Patentee before: GETWELL HEALTH TECHNOLOGY (WUHU) Co.,Ltd. Patentee before: Jiadong Technology (Shenzhen) Co.,Ltd. |