CN108272477A - A kind of GI Medicine multifunctional active sampling analysis device - Google Patents
A kind of GI Medicine multifunctional active sampling analysis device Download PDFInfo
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- CN108272477A CN108272477A CN201810042700.5A CN201810042700A CN108272477A CN 108272477 A CN108272477 A CN 108272477A CN 201810042700 A CN201810042700 A CN 201810042700A CN 108272477 A CN108272477 A CN 108272477A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
- A61B10/02—Instruments for taking cell samples or for biopsy
- A61B10/04—Endoscopic instruments
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
- A61B10/0045—Devices for taking samples of body liquids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
- A61B10/0045—Devices for taking samples of body liquids
- A61B2010/0061—Alimentary tract secretions, e.g. biliary, gastric, intestinal, pancreatic secretions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
- A61B10/02—Instruments for taking cell samples or for biopsy
- A61B10/04—Endoscopic instruments
- A61B2010/045—Needles
Abstract
The invention discloses a kind of GI Medicine multifunctional active sampling analysis devices,Including in-vivo analysis case,It is equipped in in-vivo analysis case between solid detection between liquid detecting,In-vivo analysis box top is equipped with living sampling device and solid funnel,Solid funnel bottom end is equipped with centrifugal device and Solids Analyzer,Centrifugal device includes the rotating disk being fixed on by transverse slat between solid detection,Rotating disk top surface is installed with solid sample collecting bottle,Top is equipped with and takes liquid pump between liquid detecting,It takes liquid pump bottom end to be connected with liquid sample and transmits pipe,Fluid sample, which transmits, is equipped with solution treatment cylinder and fluid analyte meter below pipe,It is inserted with agitating device in solution treatment cylinder,In vivo detection speed is fast,Digestive juice can be extracted,It scrapes and takes food or alimentary canal tapetum cell fragment,Grip sick cell or tissue,Multipath extracts biopsy sample from the patient,And sampler small and exquisite exquisiteness,Alleviate the pain that patient is extracted during biopsy sample.
Description
Technical field
The present invention relates to the field of medical instrument technology, specially a kind of GI Medicine is filled with multifunctional active sampling analysis
It sets.
Background technology
GI Medicine patient normally drains operation due to alimentary system problem, to affect body, in order to specific
The data for analyzing the various digestion liquid hold-ups of stomach, need to extract the mixtures such as patient's stomach digestive juice by equipment, then
Judge that stomach disease state, the prior art can only first pass through medical staff's sampling, analyzed, efficiency is low by detecting
Under, increase the work difficulty of medical staff.
Application No. is a kind of GI Medicine living body sampling analytical equipments of 201710044051.8 disclosure of the invention, including shell
The lower end of body, the shell is equipped with apocenosis passage, and the lower end of the apocenosis passage is equipped with liquid reserve tank, and the bottom of the liquid reserve tank is set
There are outlet tube, the outlet tube to be equipped with the first valve, the lateral wall of the shell is equipped with display screen, the upper end of the shell
Equipped with switch, the first connecting seat and the second connecting seat, through the first connecting tube is equipped on first connecting seat, described first connects
The upper end taken over is connected with sucking pump, and suction pipe is connected on the sucking pump, and the suction pipe is equipped with graduation mark, and the suction pipe is far from suction
One end of pump is equipped with sampling air bag, and the surface of the sampling air bag is equipped with through-hole and slot scraping, and the bottom of the slot scraping is equipped with volume
Slot, through being equipped with the second connecting tube on second connecting seat.The present invention realizes sampling and analysing integration, does not have to medical care people
Member carries out cumbersome operation, time saving and energy saving, improves the working efficiency of medical staff.But the invention can only extract patient's alimentary canal
Interior digestive juice, extraction sample is few, and the invention peeps structure without interior, and sampling air bag empirically can only be goed deep into patient by doctor
In alimentary canal, it is susceptible to error, to cause sampling spot inaccurate, to cause larger bad of last result error
Consequence.
Existing in-vivo analysis device has the following disadvantages and problem：
(1) can only detection and analysis digestive juice or active somatic cell, sample extraction amount is limited, and the result after detection simultaneously can not
It leans on, and detection speed is slow；
(2) living body detection device and live body extraction element are usually separated, this results in extracting live body extraction element
Biopsy samples put living body detection device into during can waste the plenty of time, be unfavorable for the quick judgement of patient's state of an illness；
(3) general live body extraction element is easy to pierce due to clamp device front end is excessively sharp after entering patient's alimentary canal
The alimentary canal of sick and wounded people, and general extraction element only has a kind of its function, for example, in pry through, live body gripping, extract gastric juice
Deng one kind in operation, if desired a variety of samples, then need the combination of a variety of different extraction elements, takes considerable time, and
Extend the pain of patient.
Invention content
In order to overcome the shortcomings of that prior art, the present invention provide a kind of GI Medicine multifunctional active sampling analysis
Device the biopsy sample of solid biopsy sample and liquid can carry out analysis detection respectively between solid detection between liquid detecting,
In vivo detection speed is fast, can extract digestive juice, scrape and take food or alimentary canal tapetum cell fragment, gripping sick cell or tissue,
Multipath extracts biopsy sample, and sampler small and exquisite exquisiteness from the patient, alleviates patient and is extracted biopsy sample process
In pain, can effectively solve the problem that background technology propose the problem of.
The technical solution adopted by the present invention to solve the technical problems is：A kind of GI Medicine multifunctional active sampling point
Analysis apparatus, including in-vivo analysis case, the in-vivo analysis case is interior to be equipped between solid detection between liquid detecting, the in-vivo analysis
Box top is equipped with living sampling device, and the in-vivo analysis box top is equipped with the solid leakage right between solid detection
Bucket；
The solid funnel is hinged with sealing cover, and solid funnel bottom end is equipped with the centrifugation being located between solid detection
Device and the Solids Analyzer immediately below centrifugal device, the centrifugal device include being mounted between solid detection by transverse slat
Interior rotating disk, the rotating disk top surface are installed with solid sample collecting bottle, are hinged at the top of the solid sample collecting bottle
There are seal bottle cap, solid sample collecting bottle bottom to be connected with sample flow pipe；
Top is equipped with the liquid pump that takes being mounted on by mounting bracket on in-vivo analysis case between the liquid detecting, described to take liquid pump
Bottom end is connected with liquid sample and transmits pipe, and the fluid sample transmits the solution treatment for being equipped with and being located in liquid detecting below pipe
Cylinder and the fluid analyte meter positioned at solution treatment cylinder bottom end are inserted with agitating device in the solution treatment cylinder.
As a kind of preferred technical solution of the present invention, between the solid detection between liquid detecting between by sealing every
Plate separates, and is equipped with liquor box between the solid detection and in liquid detecting, the liquor box bottom end is connected with weeping pipe, institute
It states and solvent valve is installed on weeping pipe.
As a kind of preferred technical solution of the present invention, sample flow tube bottom end extends to above Solids Analyzer,
Sample flow tube top end is equipped with switch valve.
As a kind of preferred technical solution of the present invention, solution treatment cylinder bottom end is connected with liquid line, the liquid
Tube bottom end is equipped with fluid analyte meter, and control valve is equipped on the liquid line.
As a kind of preferred technical solution of the present invention, the living sampling device include across in-vivo analysis case top simultaneously
With the connecting tube for taking liquid pump to connect, the connecting tube top is connected with extraction hose, has sampling in the end set for extracting hose
Block is also associated with endoscope and image processing device in the side for extracting hose.
Further, curet is also connected with by connecting line on solid funnel, curet is movably arranged on in-vivo analysis case
On, when living sampling device takes out solid-state live body in the alimentary canal of human body, solid-state live body is scraped into solid using curet and is leaked
In bucket.
Further, several drawing liquid holes are provided on sampling block, extract hose and sample several drawing liquid holes on block
Connection, several drawing liquid holes are uniformly distributed on the outer surface of sampling block, take liquid pump by drawing liquid hole that patient is in the digestive tract
Digestive juice, which is drawn onto, to be extracted in hose, subsequently into being detected analysis between liquid detecting.
As a kind of preferred technical solution of the present invention, the endoscope and image processing device include embedded in extract hose side and with sampling
The fiber hose of block connection, is equipped with several light guide bundles and image guide bundles in the fiber hose, the light guide bundles both ends are set respectively
Several light holes for having light source and being located on sampling block.
As a kind of preferred technical solution of the present invention, the sampling block is equipped with several imaging holes and connects with hose is extracted
Logical drawing liquid hole, the image guide bundles are inserted into imaging hole, and the image guide bundles top and bottom end are respectively equipped with mounted on fiber hose top
The eyepiece at end and the object lens being plugged in imaging hole.
As a kind of preferred technical solution of the present invention, the sampling block is equipped with opening court in mushroom and sampling block bottom end
On scraping slot, be equipped with circular hole, square mounting hole and arc groove in the sampling block successively from top to bottom, and circular hole, rectangular
Live body clamp device is inserted in mounting hole and arc groove jointly.
Compared with prior art, the beneficial effects of the invention are as follows：
(1) present invention links together In vivo detection case and live body extraction element, reduces extraction live body to detection sample
The interlude of product, live body can be parsed out its ingredient, can distinguish solid work between liquid detecting between solid detection faster
The biopsy sample of body sample and liquid carries out analysis detection, and centrifugal device and agitating device make live body to the processing of biopsy sample
Sample reacts faster, accelerates the speed of in-vivo analysis and detection, keeps the result of detection relatively reliable；
(2) present invention is by the way that imaging hole, light hole, drawing liquid hole to be each provided on sampling block, and samples and be additionally provided with above block
Scraping slot is also equipped with live body clamp device in it, and sampling block can be accurately positioned after entering in patient's alimentary canal, and sampling
Block can also complete extract digestive juice, scrape take food or alimentary canal tapetum cell fragment, gripping the operations such as sick cell or tissue, make
The analysis sample of live body is more various, and analysis source is more, as a result more accurate, also more accurate to the judgement of patient's state of an illness；
(3) present invention is smaller into patient's sampling block in the digestive tract, extraction hose, fiber hose volume, special
Structure design make sampling block will not injured patients alimentary canal, pain of patient when extracting biopsy sample can be mitigated.
Description of the drawings
Fig. 1 is the overall structure diagram of the present invention；
Fig. 2 is the living sampling device structural schematic diagram of the present invention；
Fig. 3 is the live body clamp device structural schematic diagram of the present invention.
In figure：1- in-vivo analysis casees；Between the detection of 2- solids；Between 3- liquid detectings；4- living sampling devices；5- partition boards；6-
Liquor box；7- endoscope and image processing devices；8- samples block；9- live body clamp devices；
101- mounting brackets；102- takes liquid pump；103- transverse slats；104- curets；
201- solid funnels；202- sealing covers；203- centrifugal devices；204- rotating disks；205- solid sample collecting bottles；
206- sample flow pipes；207- Solids Analyzers；208- switch valves；209- bottle caps；
301- fluid samples transmit pipe；If 302- solution process cartridges；303- agitating devices；304- liquid lines；305- is controlled
Valve；306- fluid analyte meters；
401- connecting tubes；402- extracts hose；403- drawing liquids hole；
601- weeping pipes；602- solvent valves；
701- fiber hoses；702- light guide bundles；703- image guide bundles；704- light sources；705- light holes；706- imaging holes；
707- eyepieces；708- object lens；
801- scrapes slot；802- circular holes；803- square mounting holes；804- arc grooves；805- wheel shaft limiting slots；
901- telescopic rods；902- the two-sided racks；903- hemispherical Shell fixtures；Half gears of 904-；905- crochet hooks；906- hangnails；
907- wheel shafts.
Specific implementation mode
As shown in Figure 1, the present invention provides a kind of GI Medicine multifunctional active sampling analysis device, retouch for convenience
It states, following cells, cell fragment etc. are referred to as solid-state live body, and the substances such as blood plasma, digestive juice are referred to as liquid live body.Including work
Body analyzes case 1, is equipped in the in-vivo analysis case 1 between solid detection 3 between 2 and liquid detecting, 1 top peace of the in-vivo analysis case
Equipped with living sampling device 4, between solid detection 3 between 2 and liquid detecting between separated by sealing partition board 5, so that solid-state is lived
The analysis detection and the analysis of liquid live body detection of body are not interfere with each other.Between solid detection 3 between 2 and liquid detecting in be equipped with
Liquor box 6 contains different reaction solution or catalyst in two liquor boxs 6, can accelerate solid-state live body and liquid live body
Reaction speed makes the analyze speed of live body greatly speed up.6 bottom end of the liquor box is connected with weeping pipe 601, the weeping pipe
Solvent valve 602 is installed on 601, controls the outflow or reservation of solution in liquor box 6.
1 top of the in-vivo analysis case is equipped with the solid funnel 201 right over 2 between solid detection, solid-state live body
From solid funnel 201 into 2 between solid detection, the detection time of solid-state live body is shortened, it is convenient and efficient.The solid leakage
201 bottom ends struggle against equipped with 2 centrifugal device 203 and the Solids Analyzer immediately below centrifugal device 203 between solid detection
207, Solids Analyzer 207 can detect solid live body, such as cell, the swill organizing and be attached on alimentary canal inner wall
Chemical composition, can have disease to alimentary canal patient provide a good etiological analysis foundation.
For convenience of the solid-state live body on living sampling device 4 is taken off, also connected by connecting line on solid funnel 201
There are curet 104, curet 104 to be placed on when not used on in-vivo analysis case 1.When living sampling device 4 is in the alimentary canal of human body
When taking out solid-state live body, easily solid-state live body can be scraped in solid funnel 201 using curet 104, hence into solid
2 between detection, the analysis and detection of solid-state live body are facilitated.201 top of the solid funnel is hinged with sealing cover 202, to be checked
The solid-state live body of survey enters in the process finished to detection between solid detection, all covers sealing cover 202 in solid-state funnel 201,
Ensure that the environment of experimental analysis is not contaminated, in-vivo analysis result is more acurrate.
The centrifugal device 203 includes being mounted on rotating disk 204 between solid detection in 2, the rotation by transverse slat 103
204 top surface of disk is installed with solid sample collecting bottle 205, and 205 top of the solid sample collecting bottle is hinged with bottle cap 209,
Bottle cap 209 can be when biopsy sample receives centrifugal force, and live body will not drop out solid sample collecting bottle 205.The solid-like
205 bottom of product collecting bottle is connected with sample flow pipe 206, and 206 bottom end of sample flow pipe extends on Solids Analyzer 207
Side, 206 top of sample flow pipe are equipped with switch valve 208, and switch valve 208 controls biopsy sample in solid collecting bottle 205
Outflow and do not flow out.
Epimere solid-state in-vivo analysis detect the step of be：First solid-state live body is scraped down from sampling block 8, then from solid
Body drain bucket 201 is put into solid sample collecting bottle 205, solid by realizing that ready reaction solution or catalyst are put into liquor box 6
In body sample collecting bottle 205, sealing cover 202 and bottle cap 209 are closed.Then startup rotating disk 204, which makes rotating reach, makes
The speed of cell centrifugation, after cell centrifuges, various substances are separated from each other, and make subsequent in-vivo analysis speed faster.At this moment
Turn on the switch valve 208, make the live body solution after centrifugation from sample flow pipe 206 enter Solids Analyzer 207 in receive detection with
Analysis.
Centrifugal device 203 is that powerful centrifugal force is generated when being rotated using objects at high speed according to centrifugal principle, makes to be placed in rotation
Sedimentation or floating occur for the suspended particulate in swivel, to the purpose for making certain particles reach concentration or be detached with other particles.
Here sometimes referred as cell, organelle, virus and large biological molecule of suspended state etc. is made in suspended particulate.Cell centrifuges energy
So that internal various structures and impurity is mutually separated, keeps the detection of active somatic cell more simple and quick.
3 tops, which are equipped with to be mounted on in-vivo analysis case 1 by mounting bracket 101, between the liquid detecting takes liquid pump 102, institute
It states and 102 bottom end of liquid pump is taken to be connected with liquid sample transmission pipe 301, the fluid sample, which transmits 301 lower section of pipe and is equipped with, is located at liquid
Solution treatment cylinder 302 in 3 between detection and the fluid analyte meter 306 positioned at 302 bottom end of solution treatment cylinder, the solution treatment cylinder
Agitating device 303 is inserted in 302, agitating device 303 makes liquid live body accelerate reaction, to accelerate the analysis of liquid live body
Detection speed.302 bottom end of solution treatment cylinder is connected with liquid line 304, and 304 bottom end of the liquid line is equipped with fluid analyte meter
306, fluid analyte meter 306 can detect the chemical composition and nutritional ingredient of the live body of the liquid such as patient's gastric juice, digestive juice, thus may be used
What kind of substance judgement lacks or lacks what kind of digestive ferment in patient body.Control valve 305 is installed on the liquid line 304, is opened
Control valve 305 can make the outflow out of solution treatment cylinder 302 of liquid live body.
The step of epimere liquid In vivo detection is：Under the extraction for taking liquid pump 102, the liquid live body in the digestive tract of patient
Such as Gastric juice digestion liquid substance is flowed into solution treatment cylinder after living sampling device 4 enters in liquid sample transmission pipe 301
In 302.First determine that control valve 305 is closed state, is then added to the reaction solution prepared in liquor box 6 and catalyst etc.
Liquid in vivo, opens agitating device 303, and agitating device 303 makes liquid live body accelerate and fully reacts, after completion of the reaction, beats
Open control valve 305, react the biopsy sample that finishes from solution conduit 304 flow to fluid analyte meter 306 be inscribed it is examined, at this moment due to
The pre-processing of sample finishes, so the detection speed of liquid biopsy sample is made to greatly promote, has saved the time.
Here it should be noted that, above takes liquid pump 102 to use micropump, has suction capacity, has and be not inserted into human body
Alimentary canal can draw the function of digestive juice, and micropump suction force is not very big, makes patient when being drawn digestive juice
It will not feel bad, alleviate the pain during patient is taken live body.
The living sampling device 4 include across 1 top of in-vivo analysis case and with the connecting tube 401 that takes liquid pump 102 to connect,
401 top of the connecting tube, which is connected with, extracts hose 402, has sampling block 8 in the end set for extracting hose 402, in sampling block 8
On be provided with several drawing liquid holes 403, extract hose 402 and connect with several drawing liquid holes 403 on sampling block 8, several drawing liquid holes
403 are uniformly distributed on the outer surface of sampling block 8, so that extraction hose 402 is extracted the digestive juice of more direction, the sample taken
Capacity can bigger.402 side of extraction hose is also associated with endoscope and image processing device 7.
Epimere extract patient's liquid biopsy sample the step of be：After sampling block 8 is filled in patient's alimentary canal, peeped using interior
The position of the observation sampling block 8 of device 7 and the position of the block 8 of adjustment sampling at any time, make sampling block 8 reach patient in the digestive tract suitable
Behind position, unlatching takes liquid pump 102, and liquid pump 102 is taken to inhale patient's digestive juice in the digestive tract from drawing liquid hole 403 using pull of vacuum
To extracting in hose 402, subsequently into being detected analysis between liquid detecting 3.
As depicted in figs. 1 and 2, the endoscope and image processing device 7 includes being connect embedded in extraction 402 side of hose and with sampling block 8
Fiber hose 701 is equipped with several light guide bundles 702 and image guide bundles 703,702 both ends of the light guide bundles in the fiber hose 701
Several light holes 705 for being respectively equipped with light source 704 and being located on sampling block 8, light source 704 are located at outside patient body, will not enter disease
In human body, patient safety is protected, the heat for avoiding light source enters in patient body to causing to burn in patient body.It is described to take
The drawing liquid hole 403 that sample block 8 is equipped with several imaging holes 706 and is connected to extraction hose 402, the image guide bundles 703 are inserted into imaging
Hole 706,703 top of the image guide bundles and bottom end be respectively equipped with mounted on 701 top of fiber hose eyepiece 707 and be plugged in into
As the object lens 708 in hole 706.
Light guide bundles 702 and image guide bundles 703 are made of tens thousand of glass fibres, and fiber is superfine, about the 1/10 of hair, soft
It is soft flexible.Every fiber conducts a luminous point, and the light head and the tail of the light glass whole marshalling in scope, both ends are right
It answers, all tens thousand of a luminous points are from one end to the other end, if what is arranged between every fiber is closer, both ends are more neat, conduction
The brightness of image is bigger, and resolution ratio is higher, and image is more clear.So fiber hose 701 can be very thin, diameter is about 2-
4mm does not take up space, and it is small to go deep into the gastral hose overall volume of patient, reduces patient and is extracting hose 402 and fiber hose
701 feel bad sense into patient is gastral.
The operation principle of epimere endoscope and image processing device 7 is：After sampling block 8 enters patient's esophagus, the light that light source 704 is sent out exists
It is propagated in light guide bundles 702, irradiates and out of light hole 705, the substance near sampling block 8 can be illuminated, make sampling block 8 to live body
Sample rate faster, sample position it is more acurrate.
The sampling block 8 is equipped with opening up scraping slot 801 in mushroom and 8 bottom end of sampling block, is reached in sampling block 8
Behind some position, sampling block 8 can be made to move up and down, at this moment because of the special shape of sampling block 8, the corner angle of 8 side of sampling block
Patient's some swills in the digestive tract or the substance detached with inner wall of the pipe are scraped off, the substance scraped off enters scraping
Then slot 801 pulls extraction hose 8 that sampling block 8 can be made to be come out with scraping solid sample.
As shown in figure 3, it is recessed to be equipped with circular hole 802, square mounting hole 803 and arc in the sampling block 8 successively from top to bottom
Slot 804, and it is inserted with live body clamp device 9 jointly in circular hole 802, square mounting hole 803 and arc groove 804.The live body
Clamp device 9 includes being plugged in circular hole 802, square mounting hole 803, the telescopic rod 901 in arc groove 804, double cog respectively
902, two hemispherical Shell fixtures 903 of item, 901 bottom end of the telescopic rod are fixedly connected with the two-sided rack 902, hemispherical Shell fixture 903
One end is engaged by half gear 904 with the two-sided rack 902, and telescopic rod 901 drives 902 upper and lower displacement of the two-sided rack, to make folder
Tool lifts and grips biopsy sample.
The left and right sides of the two-sided rack 902 is designed with tooth socket, when 902 upper and lower displacement of the two-sided rack, hemispherical Shell is promoted to press from both sides
After tool 903 reaches suitable position, two and half gears 904 can all rotate that two hemispherical Shell fixtures 903 is made to unclamp, at this moment
Grip patient's pathological tissues in the digestive tract, cell etc..One semi-area of outside of half gear 904 is equipped with continuous external tooth, energy
Make half gear 904 when non-rotary, since half gear 904 side with teeth is not contacted with the hole wall of square mounting hole 803,
The two-sided rack 902 can more easily control drive half gear 904 and hemispherical Shell fixture 903 to be slided up and down in square mounting hole 803.
Half gear 904 described in two is located at the left and right side of the two-sided rack 902, and half gear, 904 center plugs
There is wheel shaft 907, is equipped with wheel shaft limit sliding chutes 805 in sampling block 8, the both ends of wheel shaft 907 are plugged in wheel shaft limit sliding chutes 805
It is interior, it ensure that the stability when stability of half gear 904 movement and hemispherical Shell fixture 903 grip active somatic cell.In double cog
The end set of item 902 has crochet hook 905, and crochet hook 905 to be equipped with several hangnails 906, and hangnail 906 can be such that crochet hook 905 penetrates
Cell or tissue will not drop out, and improve the gripping success rate of biopsy sample.To ensure that half gear 904 does not skid off arc groove
804 and make hemispherical Shell fixture 903 abjection control, before not gripping biopsy sample, contraction pole 901 is in contraction state, at this moment crochet hook
905 lower horizontal height is less than the lower horizontal height of hemispherical Shell fixture 903, prevents sampling block 8 from entering patient's alimentary canal mistake
Patient is stabbed in journey.Half gear 904 and the upper and lower displacement in square mounting hole 803 of the two-sided rack 902.
The application grip biopsy sample the step of be：In the sampling arrival patient's alimentary canal of block 8 behind accurate sample position, stretch
Contracting bar 901 drives the two-sided rack 902 to decline elongation, at this moment since the gear teeth and hemispherical Shell fixture 903 of half gear 904 are by rectangular peace
The reason that is limited of dress hole 803, half gear 904 do not rotate, the band of half gear 904 and hemispherical Shell fixture 903 in the two-sided rack 902
To bottom offset, when half gear 904 enters arc groove 804, bottom side and the wheel shaft limit sliding chutes 805 of wheel shaft 907 under dynamic
Bottom end be affixed, wheel shaft limit sliding chutes 805 make wheel shaft 907 and half gear 904 will not displacement still further below.At this moment arc groove is permitted
Perhaps half gear 904 rotates, and the rotation of half gear 904 drives two 903 bottom ends of hemispherical Shell fixture to be separated from each other, and then crochet hook 905 exists
It is inserted into sick cell or tissue under the movement of the two-sided rack 902.Then telescopic rod 901 drives the two-sided rack 902 to rise, two
903 bottom end of hemispherical Shell fixture, which mutually closes up, clamps biopsy samples and to 803 contract of square mounting hole, hemispherical Shell fixture 903 exists
It will not be unclamped in square mounting hole 803, and the design of crochet hook 905 makes biopsy sample completely be taken out of the alimentary canal of patient, takes out
Biopsy samples are reliable, and quality is kept.
It need to supplement, be shunk in telescopic rod 901 and the two-sided rack 902 is driven to rise, to make the two-sided rack 902 drive
Hemispherical Shell fixture 903 is retracted in square mounting hole 803, after telescopic rod 901 is retracted to the limit, the bottom end water of hemispherical Shell fixture 903
Flat height is higher than the lower horizontal height for sampling block 8, and so that sampling block 8 is entered, patient is gastral will not to accidentally injure digestion in the process
Road, it is safer, further the bottom face of hemispherical Shell fixture 903 can be set as arc surface, when gripping biopsy sample in this way, can reduced
The gastral risk of patient is stabbed in 903 bottom end of hemispherical Shell fixture, reduces the pain of patient.
Imaging hole 706, light hole 705, drawing liquid hole 403 are each provided on sampling block 8 by the present invention, and are sampled block 8 and gone back above
Equipped with scraping slot 801, live body clamp device 9 is also equipped in it, it is small that such design enters patient's sampling block 8 in the digestive tract
It is skilful exquisite, reduce the pain of patient.Block 8 is sampled after entering in patient's alimentary canal, can be accurately positioned, and sampling block 8 can also
Complete extract digestive juice, scrape take food or alimentary canal tapetum cell fragment, gripping sick cell or tissue operation, make live body
It is more various to analyze sample, analysis source is more, as a result more accurate, also more accurate to the judgement of patient's state of an illness.
It is obvious to a person skilled in the art that invention is not limited to the details of the above exemplary embodiments, Er Qie
In the case of without departing substantially from spirit or essential attributes of the invention, the present invention can be realized in other specific forms.Therefore, no matter
From the point of view of which point, the present embodiments are to be considered as illustrative and not restrictive, and the scope of the present invention is by appended power
Profit requires rather than above description limits, it is intended that all by what is fallen within the meaning and scope of the equivalent requirements of the claims
Variation is included within the present invention.Any reference signs in the claims should not be construed as limiting the involved claims.
Claims (7)
1. a kind of GI Medicine multifunctional active sampling analysis device, including in-vivo analysis case (1), it is characterised in that：It is described
Equipped between solid detection (2) between liquid detecting (3) in in-vivo analysis case (1), work is installed at the top of the in-vivo analysis case (1)
Body sampler (4) and the solid funnel (201) between solid detection above (2)；
Sealing cover (202) is hinged at the top of the solid funnel (201), solid funnel (201) bottom end, which is equipped with, is located at solid
The centrifugal device (203) of (2) and the Solids Analyzer (207) below centrifugal device (203), the centrifugal device between detection
(203) include the rotating disk (204) for passing through transverse slat (103) between solid detection in (2), rotating disk (204) top surface
It is installed with solid sample collecting bottle (205), bottle cap (209) is hinged at the top of the solid sample collecting bottle (205), it is described
Solid sample collecting bottle (205) bottom is connected with sample flow pipe (206)；
(3) top, which is equipped with to be mounted on in-vivo analysis case (1) by mounting bracket (101), between the liquid detecting takes liquid pump
(102), described that liquid pump (102) bottom end is taken to be connected with liquid sample transmission pipe (301), the fluid sample transmits under pipe (301)
Side is equipped with the solution treatment cylinder (302) between liquid detecting in (3) and the fluid analysis positioned at solution treatment cylinder (302) bottom end
Instrument (306), the solution treatment cylinder (302) is interior to be inserted with agitating device (303).
2. a kind of GI Medicine multifunctional active sampling analysis device according to claim 1, it is characterised in that：It is described
(2) are separated between (3) by sealing partition board (5) between liquid detecting between solid detection, (2) and liquid inspection between the solid detection
It is equipped with liquor box (6) between survey in (3), liquor box (6) bottom end is connected with weeping pipe (601), on the weeping pipe (601)
Solvent valve (602) is installed.
3. a kind of GI Medicine multifunctional active sampling analysis device according to claim 1, it is characterised in that：It is described
Sample flow pipe (206) bottom end extends to above Solids Analyzer (207), and sample flow pipe (206) top is equipped with out
Close valve (208).
4. a kind of GI Medicine multifunctional active sampling analysis device according to claim 1, it is characterised in that：It is described
Solution treatment cylinder (302) bottom end is connected with liquid line (304), and liquid line (304) bottom end is equipped with fluid analyte meter (306),
Control valve (305) is installed on the liquid line (304).
5. a kind of GI Medicine multifunctional active sampling analysis device according to claim 1, it is characterised in that：It is described
Living sampling device (4) include across in-vivo analysis case (1) top and with the connecting tube (401) that takes liquid pump (102) to connect, it is described
Connecting tube (401) top, which is connected with, extracts hose (402), has sampling block (8) in the end set for extracting hose (402), is taking out
The side of hose (402) is taken to be also associated with endoscope and image processing device (7).
6. a kind of GI Medicine multifunctional active sampling analysis device according to claim 1, it is characterised in that：Solid
Curet (104) is also connected with by connecting line on body drain bucket (201), curet (104) is movably arranged on in-vivo analysis case (1),
When living sampling device (4) takes out solid-state live body in the alimentary canal of human body, solid-state live body is scraped admittedly using curet (104)
In body drain bucket (201).
7. a kind of GI Medicine multifunctional active sampling analysis device according to claim 5, it is characterised in that：It is taking
It is provided with several drawing liquid holes (403) on sample block (8), extracts hose (402) and connects with several drawing liquid holes (403) on sampling block (8)
It connects, several drawing liquid holes (403) are uniformly distributed on the outer surface of sampling block (8), and liquid pump (102) is taken to pass through drawing liquid hole (403)
Patient's digestive juice in the digestive tract is drawn onto and is extracted in hose (402), analysis is detected subsequently into (3) between liquid detecting.
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| CN201810042700.5A CN108272477B (en) | 2018-01-17 | 2018-01-17 | Gastroenterology is with multi-functional live body sampling analysis device |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN111505255A (en) * | 2020-04-20 | 2020-08-07 | 南通市第一人民医院 | Gastroenterology biopsy analysis device |
| CN112284850A (en) * | 2020-10-22 | 2021-01-29 | 四川大学华西医院 | Intelligent analysis front-end processing equipment after gastroenterology biopsy |
| CN112881082A (en) * | 2021-01-18 | 2021-06-01 | 内蒙古京海煤矸石发电有限责任公司 | Visual sampling detection device under industrial dim light environment based on AI video technology |
| CN113109073A (en) * | 2021-05-28 | 2021-07-13 | 山东交通学院 | Coal sampling device |
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| US20110295149A1 (en) * | 2007-08-06 | 2011-12-01 | The Regents Of The University Of California | Apparatus for solubilizing tissue |
| CN105954503A (en) * | 2016-04-13 | 2016-09-21 | 郑伟 | Apparatus for sampling and analyzing living body in department of gastroenterology |
| CN106725630A (en) * | 2017-01-19 | 2017-05-31 | 张耀亮 | A kind of GI Medicine living body sampling analytical equipment |
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| CN1520786A (en) * | 2003-01-28 | 2004-08-18 | 上海第二医科大学附属仁济医院 | Liquid extracting apparatus for nerve endoscope operation |
| US20110295149A1 (en) * | 2007-08-06 | 2011-12-01 | The Regents Of The University Of California | Apparatus for solubilizing tissue |
| CN105954503A (en) * | 2016-04-13 | 2016-09-21 | 郑伟 | Apparatus for sampling and analyzing living body in department of gastroenterology |
| CN106725630A (en) * | 2017-01-19 | 2017-05-31 | 张耀亮 | A kind of GI Medicine living body sampling analytical equipment |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111505255A (en) * | 2020-04-20 | 2020-08-07 | 南通市第一人民医院 | Gastroenterology biopsy analysis device |
| CN112284850A (en) * | 2020-10-22 | 2021-01-29 | 四川大学华西医院 | Intelligent analysis front-end processing equipment after gastroenterology biopsy |
| CN112881082A (en) * | 2021-01-18 | 2021-06-01 | 内蒙古京海煤矸石发电有限责任公司 | Visual sampling detection device under industrial dim light environment based on AI video technology |
| CN112881082B (en) * | 2021-01-18 | 2022-06-07 | 内蒙古京海煤矸石发电有限责任公司 | Visual sampling detection device under industrial dim light environment based on AI video technology |
| CN113109073A (en) * | 2021-05-28 | 2021-07-13 | 山东交通学院 | Coal sampling device |
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| CN108272477B (en) | 2021-04-30 |
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