CN108261437A - A kind of concocting method suitable for Cortex Eucommiae cutting - Google Patents

A kind of concocting method suitable for Cortex Eucommiae cutting Download PDF

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Publication number
CN108261437A
CN108261437A CN201810083035.4A CN201810083035A CN108261437A CN 108261437 A CN108261437 A CN 108261437A CN 201810083035 A CN201810083035 A CN 201810083035A CN 108261437 A CN108261437 A CN 108261437A
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China
Prior art keywords
cortex eucommiae
cutting
block
cortex
medicine
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Pending
Application number
CN201810083035.4A
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Chinese (zh)
Inventor
周建华
肖建新
杨德民
段晓慧
李金林
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Jiangxi Qingchunkangyuan Herbal Medicine Co Ltd
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Jiangxi Qingchunkangyuan Herbal Medicine Co Ltd
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Priority to CN201810083035.4A priority Critical patent/CN108261437A/en
Publication of CN108261437A publication Critical patent/CN108261437A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/46Eucommiaceae (Eucommia family), e.g. hardy rubber tree
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10Preparation or pretreatment of starting material
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10Preparation or pretreatment of starting material
    • A61K2236/13Preparation or pretreatment of starting material involving cleaning, e.g. washing or peeling
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10Preparation or pretreatment of starting material
    • A61K2236/15Preparation or pretreatment of starting material involving mechanical treatment, e.g. chopping up, cutting or grinding
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10Preparation or pretreatment of starting material
    • A61K2236/17Preparation or pretreatment of starting material involving drying, e.g. sun-drying or wilting

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Fodder In General (AREA)

Abstract

The invention discloses a kind of processing and concocting methods suitable for Cortex Eucommiae cutting.The Cortex Eucommiae for scraping off tertia is taken, thickness stepping is cleaned, put in transfer container, bored profit 2h, until neither too hard, nor too soft;Then the Cortex Eucommiae moistened is put on reciprocating medicine cutter respectively by thickness stepping, it is sized, cutting frequency is adjusted, first pitch is put Cortex Eucommiae, is put on medicine cutter conveyer belt, crosscutting;Then by crosscutting good Cortex Eucommiae, sideway is on medicine cutter conveyer belt again, and rip cutting obtains the Cortex Eucommiae block that silk is connected to, and measuring size should meet the requirements, until meeting the requirements.Then more Cortex Eucommiaes are once put by identical method, cutting is carried out, obtains the Cortex Eucommiae block that silk is connected to, then appropriate Cortex Eucommiae block is put in the empty medicine cookeding pot that temperature is 40 50 DEG C or so and rotated 5 minutes, Cortex Eucommiae silk disconnects automatically, takes out, sieving obtains qualified Cortex Eucommiae block.This method substantially increases production efficiency under the premise of product quality is ensured, reduces the production cost of Cortex Eucommiae, has saved the production time.

Description

A kind of concocting method suitable for Cortex Eucommiae cutting
Technical field
The present invention relates to Chinese medicine processing technique field more particularly to a kind of concocting methods suitable for Cortex Eucommiae cutting.
Background technology
Cortex Eucommiae is the dry bark of Eucommiaceae plant Cortex Eucommiae Eucommia ulmoides Oliv..It is loaded in《Legendary god of farming's book on Chinese herbal medicine Through》Top grade has the effect of filling liver kidney, strengthening the bones and muscles, tocolysis, blood pressure lowering.Document report, also calm, enhancing adrenal cortex Function activates the nonspecific immunity of body to react, and has Biphasic Regulation to cellular immune function.Cortex Eucommiae system conventional Chinese medicine, Purposes is wide, and dosage is big, and successive dynasties application is emphasized to be used as medicine after processing.Ancients process it research and have accumulated abundant practical experience, From Liu Song when《Lei Gong Pao Zhi Lun》Begin the concocting method recorded, until the history of about 1400 the late Qing Dynasty, at least 62 medical literatures There is the record that Cortex Eucommiae processes data.Wherein, it is related to 17 kinds of concocting method, uses 14 kinds of auxiliary material.
Cortex Eucommiae repaiies earliest record being used as medicine afterwards《Lei Gong Pao Zhi Lun》:" all to make, to prune tertia ... ... "《Prescriptions worth thousand gold》: " it is wrong to prune empty hapalonychia, take inner taste person scale it." hereafter successive dynasties medical book, book on Chinese herbal medicine emphasize tertia and continue into the present,《Pharmacopeia》 And various regions《Concocted specification》Cortex Eucommiae is processed to be required to:" residual tertia is scraped off, is cleaned.”
Modern research shows that after tertia and scale are removed in processing, its tertia averagely accounts for Cortex Eucommiae total amount more than 20% is measured, not Remove decocting rate low 30.86% of the decocting rate compared with removal tertia block of tertia block, it is seen that tertia and scale right and wrong are removed before being used as medicine It is often necessary.
《Lei Gong Pao Zhi Lun》It carries:“...Smooth file is used." Tang《Tang materia medica》, Song《Classified Materia Meidca》Deng load:" with skiving, go Epithelium, horizontal reason are cut, and enable fracture of wire." bright《Special effect good recipe》It carries::Chopping.“《Book on Chinese herbal medicine covers bamboo fish trap》It carries:“...Nozzle flakiness.”
Cortex Eucommiae cutting specification, can be summarized as block piece, silk piece (horizontal hair piece, vertical silk piece), fourth piece and silver etc., size from 0.3cm to 3cm etc..Experiment display, horizontal hair piece decocting rate distinguish high 11.04% He than vertical silk piece and fourth piece decocting rate 13.33%.Ancients' " horizontal reason is cut, and enables fracture of wire " are reasonable.
《Chinese Pharmacopoeia》The one Cortex Eucommiae concocting method of version in 2015 is as follows:Residual tertia is scraped off, is cleaned, stripping and slicing or silk, is done It is dry.
Invention content
The present invention is for Cortex Eucommiae in existing processing procedure or stir-baked CORTEX EUCOMMIAE with salt solution machinery cutting be inconvenient, even manual cutting, efficiency Lowly, after cutting Cortex Eucommiae net system medicine materical crude slice not fracture of wire the deficiencies of provide a kind of new concocting method.
Above-mentioned purpose is realized by the following method in the present invention.
The concocting method suitable for Cortex Eucommiae or stir-baked CORTEX EUCOMMIAE with salt solution of the present invention includes the following steps:
(1) net system:Tertia is scraped off, removes the impurity in raw material, thickness stepping is cleaned, obtains clean bulk pharmaceutical chemicals;Cortex Eucommiae Thickness stepping is:Thickness is thickness more than or equal to 4mm's;Thickness is as thin less than 4mm's.
(2) bored profit:The Cortex Eucommiae cleaned is put in transfer container, bored profit 2h, until neither too hard, nor too soft;
(3) trial cut:By the Cortex Eucommiae moistened by thickness stepping, put on reciprocating medicine cutter, operate and advise by reciprocating medicine cutter Journey operates, and adjusting Cortex Eucommiae needs the size (block) of cutting, adjusts cutting frequency, and first pitch puts a small amount of Cortex Eucommiae, is put in medicine cutter biography It send and takes, it is crosscutting;Then by crosscutting good Cortex Eucommiae, for sideway on medicine cutter conveyer belt, rip cutting obtains the Cortex Eucommiae that silk is connected to again Block, measuring size should meet the requirements;
(4) batch cutting:More Cortex Eucommiaes are once put on medicine cutter conveyer belt (as long as simultaneously energy can be put on medicine cutter Cutting) by the method progress cutting under (3) item, obtain the Cortex Eucommiae block that batch silk is connected to;
(5) fracture of wire:Appropriate Cortex Eucommiae block is put in the empty medicine cookeding pot that temperature is 40-50 DEG C or so and is rotated 5 minutes, Cortex Eucommiae silk It is automatic to disconnect, it takes out, sieving obtains qualified Cortex Eucommiae block, then puts dry 3-4h in no more than 60 DEG C baking ovens of temperature;To obtain the final product.
The Cortex Eucommiae or stir-baked CORTEX EUCOMMIAE with salt solution recovery rate that this method obtains are increased slightly, and variation is little, but the production cycle is by original 1 ton of goods Need 5 days till now 1 ton of goods only need 1 day, press《Chinese Pharmacopoeia》It is all qualified to detect indices, ensure that product quality, and big Improve production efficiency greatly.Due to operating procedure simplicity, saving of work and time, product quality is more secure, and appearance is more beautiful, has It is largely produced conducive to manufacturing enterprise and cost control.
Specific embodiment
With reference to embodiment, the present invention is further illustrated, and following each embodiments are merely to illustrate the present invention, right The present invention is not restricted.
Embodiment 1
Cortex Eucommiae is taken, scrapes off tertia, removes the impurity in raw material, cleans, obtains clean bulk pharmaceutical chemicals;The Cortex Eucommiae that will have been cleaned It puts in transfer container, bored profit 2h, until neither too hard, nor too soft;Then the Cortex Eucommiae moistened is put on reciprocating medicine cutter, medicine is cut by reciprocating Machine operating instruction carries out trial cut, and adjusting Cortex Eucommiae needs the size (block) of cutting, adjusts cutting frequency, and first pitch puts a small amount of Cortex Eucommiae, It is put on medicine cutter conveyer belt, it is crosscutting;Then by crosscutting good Cortex Eucommiae, for sideway on medicine cutter conveyer belt, rip cutting obtains silk again The Cortex Eucommiae block being connected to, measures size and carries out batch cutting after meeting the requirements again.More are once put on medicine cutter conveyer belt Cortex Eucommiae (as long as simultaneously energy cutting can be put on medicine cutter) carries out cutting by the method for trial cut, obtains batch silk and is connected to Cortex Eucommiae block;Then appropriate Cortex Eucommiae block is put in the medicine cookeding pot that temperature is 40-50 DEG C or so and rotated 5 minutes, Cortex Eucommiae silk is automatic Disconnect, take out, sieving obtains qualified Cortex Eucommiae block, then put in no more than 60 DEG C baking ovens of temperature dry 3-4h to get.
Cortex Eucommiae tradition concocting method embodiment
Foundation《Chinese Pharmacopoeia》The one Cortex Eucommiae concocting method of version in 2015.
Residual tertia is scraped off, is cleaned, stripping and slicing or silk, it is dry
1 this patent method of table implements data comparison with conventional method
It although an embodiment of the present invention has been shown and described, for the ordinary skill in the art, can be with Understanding without departing from the principles and spirit of the present invention can carry out these embodiments a variety of variations, modification, replace And modification, the scope of the present invention is defined by the appended.

Claims (4)

1. a kind of processing and concocting method suitable for Cortex Eucommiae cutting, it is characterised in that:The concocting method includes the following steps:
(1) net system:Tertia is scraped off, removes the impurity in raw material, thickness stepping is cleaned, obtains clean bulk pharmaceutical chemicals;
(2) bored profit:The Cortex Eucommiae cleaned is put in transfer container, bored profit 1-3h, until neither too hard, nor too soft;
(3) trial cut:The Cortex Eucommiae of thickness stepping moistened is put on reciprocating medicine cutter, is grasped by reciprocating medicine cutter operating instruction Make, adjusting Cortex Eucommiae needs the size (block) of cutting, adjusts cutting frequency, and first pitch is put Cortex Eucommiae, is put on medicine cutter conveyer belt, horizontal It cuts;Then by crosscutting good Cortex Eucommiae, for sideway on medicine cutter conveyer belt, rip cutting obtains the Cortex Eucommiae block that silk is connected to, measuring scale again It is very little to meet the requirements;
(4) batch cutting:More Cortex Eucommiaes are once put on medicine cutter conveyer belt, it simultaneously can cutting as long as can be put on medicine cutter ;Cutting is carried out by the method under (3) item, obtains the Cortex Eucommiae block that batch silk is connected to;
(5) fracture of wire:Cortex Eucommiae block is put in the empty medicine cookeding pot that temperature is 40-50 DEG C and is rotated 3-10 minutes, Cortex Eucommiae silk disconnects automatically, Take out, sieving obtains qualified Cortex Eucommiae block, then puts dry 3-4h in no more than 60 DEG C baking ovens of temperature, be sieved to get.
2. it is suitable for the concocting method of Cortex Eucommiae cutting as described in claim 1, it is characterised in that:In step (1), Cortex Eucommiae thickness Stepping is:Thickness is thickness more than or equal to 4mm's;Thickness is as thin less than 4mm's.
3. it is suitable for the concocting method of Cortex Eucommiae cutting as described in claim 1, it is characterised in that:In step (2), it will clean Cortex Eucommiae put in transfer container, bored profit 2h, until neither too hard, nor too soft.
4. it is suitable for the concocting method of Cortex Eucommiae cutting as described in claim 1, it is characterised in that:In step (5), fracture of wire:It will Cortex Eucommiae block, which is put in the medicine cookeding pot that temperature is 40-50 DEG C or so, to be rotated 5 minutes.
CN201810083035.4A 2018-01-29 2018-01-29 A kind of concocting method suitable for Cortex Eucommiae cutting Pending CN108261437A (en)

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CN201810083035.4A CN108261437A (en) 2018-01-29 2018-01-29 A kind of concocting method suitable for Cortex Eucommiae cutting

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Application Number Priority Date Filing Date Title
CN201810083035.4A CN108261437A (en) 2018-01-29 2018-01-29 A kind of concocting method suitable for Cortex Eucommiae cutting

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106511439A (en) * 2016-12-02 2017-03-22 南昌大学 Eucommia bark processing method
CN106770695A (en) * 2016-05-21 2017-05-31 广州今典精方药业有限公司 The quality standard and manufacturing process of the bark of eucommia qualitative, quantitative prepared slices of Chinese crude drugs
CN106937964A (en) * 2017-03-03 2017-07-11 河南中医学院 A kind of concocting method of Traditional Chinese medicine eucommia bark

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106770695A (en) * 2016-05-21 2017-05-31 广州今典精方药业有限公司 The quality standard and manufacturing process of the bark of eucommia qualitative, quantitative prepared slices of Chinese crude drugs
CN106511439A (en) * 2016-12-02 2017-03-22 南昌大学 Eucommia bark processing method
CN106937964A (en) * 2017-03-03 2017-07-11 河南中医学院 A kind of concocting method of Traditional Chinese medicine eucommia bark

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
段启主编: "《中药饮片生产技术》", 31 August 2017, 广东高等教育出版社 *
肖永庆等主编: "《中药炮制学》", 30 November 2016, 中国协和医科大学出版社 *
高宾等: "杜仲的炮制加工", 《首都医药》 *

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Application publication date: 20180710

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