CN108236479A - Left atrial appendage occlusion system, occluder for left auricle and its conveyer - Google Patents
Left atrial appendage occlusion system, occluder for left auricle and its conveyer Download PDFInfo
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- CN108236479A CN108236479A CN201611218481.9A CN201611218481A CN108236479A CN 108236479 A CN108236479 A CN 108236479A CN 201611218481 A CN201611218481 A CN 201611218481A CN 108236479 A CN108236479 A CN 108236479A
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- end fixing
- distal end
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B17/12099—Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder
- A61B17/12122—Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder within the heart
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B17/12131—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
- A61B17/1214—Coils or wires
- A61B17/12145—Coils or wires having a pre-set deployed three-dimensional shape
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B17/12131—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
- A61B17/1214—Coils or wires
- A61B17/1215—Coils or wires comprising additional materials, e.g. thrombogenic, having filaments, having fibers, being coated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B17/12131—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
- A61B17/12168—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device having a mesh structure
- A61B17/12172—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device having a mesh structure having a pre-set deployed three-dimensional shape
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B2017/00743—Type of operation; Specification of treatment sites
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B2017/1205—Introduction devices
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B2017/1205—Introduction devices
- A61B2017/12054—Details concerning the detachment of the occluding device from the introduction device
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B2017/1205—Introduction devices
- A61B2017/12054—Details concerning the detachment of the occluding device from the introduction device
- A61B2017/12095—Threaded connection
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- Life Sciences & Earth Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
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Abstract
The present invention provides a kind of left atrial appendage occlusion systems, occluder for left auricle and its conveyer, the occluder for left auricle includes plug rack, proximal end fixing piece and distal end fixing piece, the conveyer includes push hollow tube and traction body, the plug rack has the first opposite proximal end and the first distal end, the proximal end fixing piece is connect with the first proximal end, the distal end fixing piece is arranged at intervals with proximal end fixing piece and is connect with the first distal end, through-hole is provided on the distal end fixing piece, the push hollow tube has the second distal end to match with proximal end fixing piece, to realize that push hollow tube and plug rack are detachably connectable, the traction body is for penetrating through-hole and detachably connectable with distal end fixing piece.The present invention can shorten the length of plug rack, to reduce length when assembled, can also reduce the outer diameter of plug rack, and at least part of plug rack is recycled in delivery sheath by order to discharge when to be positioned and discharged again.
Description
Technical field
The present invention relates to implantable medical devices technical field, more particularly to a kind of left atrial appendage occlusion system, left auricle of heart envelope
Stifled device and its conveyer.
Background technology
Auricular fibrillation (referred to as " atrial fibrillation ") is clinically most common perpetual arrhythmia, in general population, morbidity
Rate is 0.5%~1.3%.The most important harm of atrial fibrillation is to promote thrombosis, and cerebral apoplexy, outer is easy to cause after thrombus breaks loose
The complication such as all blood vessel embolisms significantly increase the disability rate and lethality of atrial fibrillation.Wherein, cerebral apoplexy is most common for atrial fibrillation and endangers
The maximum complication of evil, there are about 15,000,000 people every year in world wide to suffer from cerebral apoplexy, and 20%~25% is attributed to atrial fibrillation.Research
It has been shown that, the 60% cardiogenic thrombus of rheumatic heart disease patients with atrial fibrillation come from left auricle of heart, 90% in Non-valvular disease patients with atrial fibrillation
More than thrombus is correspondingly formed in left auricle of heart.Therefore, intervene left auricle of heart prevention patients with atrial fibrillation thromboembolism, especially cerebral apoplexy, tool
There is important clinical meaning.
Anticoagulant therapy is the conventional means for preventing atrial fibrillation palsy complication at present, but anticoagulant therapy has certain limitation.
For this purpose, existing more occlude left auricle of heart using using interventional therapy, i.e., sealed by interventional medical device, such as left auricle of heart
Stifled device solves the problems, such as the occlusion of left auricle of heart.In order to which occluder for left auricle is enabled preferably to be applied to clinic, it is desirable that left atrial appendage occlusion
Device needs implement function such as：A) left auricle of heart oral area in irregular shape, is can adapt to, eliminates due to atrial fibrillation and causes left auricle of heart
The thrombus of oral area；B) the different left auricle of heart inner cavity of anatomical structure, is can adapt to, effectively blocks left auricle of heart；C) it is fixed, can to repeat
Position, release and recycling, avoid damage to tissue；D) displacement during use etc. can, be prevented.
But existing occluder for left auricle rarely has the function that can realize above-mentioned Article 3, i.e., resetting, release and
Recycling.For example, when current caged occluder for left auricle discharges, distal end is discharged prior to proximal end, causes the anchoring on distal end
It discharges and is pierced into advance in left auricle of heart wall prior to proximal end, if resetting and recycling by force in this way, certainly will need to will be anchored from the left heart
It is pulled out in ear wall to recall plugging device, so easily pull a muscle fibr tissue, is unfavorable for surgical procedure.In addition, the left heart of caged
Ear plugging device is assembled in duration in delivery sheath and spends length, causes the length of corresponding delivery sheath accordingly to increase, and is both not easy to
Surgical procedure, and operation cost can be increased.In addition, current adjustable occluder for left auricle there are it is similary the problem of, both can not
Repeatable positioning and recycling, and it is not easy to surgical procedure.
Invention content
The purpose of the present invention is to provide a kind of left atrial appendage occlusion system, occluder for left auricle and its conveyer, to solve
Occluder for left auricle can not resetting, the problems such as recycling and assembled length are long in the prior art.
To achieve the above object, occluder for left auricle provided by the invention includes plug rack, proximal end fixing piece and distal end
Fixing piece；The plug rack has the first opposite proximal end and the first distal end；The proximal end fixing piece and first proximal end
Connection；The distal end fixing piece is arranged at intervals with the proximal end fixing piece and is connect with the described first distal end；Wherein, the distal end
Through-hole is provided on fixing piece, the proximal end fixing piece has the first inner chamber of perforation, and the first inner chamber has first axle,
The through-hole has second axis, and when the first axle is parallel with the second axis, the quantity of the through-hole is two,
When the first axle is vertical with the second axis, the quantity of the through-hole is at least one.
In addition, to achieve the above object, provided by the present invention for the conveyer of above-mentioned occluder for left auricle, including push
Hollow tube and traction body；The push hollow tube has the second distal end to match with the proximal end fixing piece, to realize
It states push hollow tube and the plug rack is detachably connectable；The traction body is used to penetrate at least one through-hole simultaneously
It is detachably connectable with the distal end fixing piece.
In addition, to achieve the above object, left atrial appendage occlusion system provided by the invention include above-mentioned occluder for left auricle with
And conveyer.
Preferably, the plug rack includes more support ribs, and the more support ribs surround the axis of the plug rack
Line is arranged；One end of the more support ribs is connect with the proximal end fixing piece, the other end of the more support ribs with it is described
Distal end fixing piece is connected.
Preferably, the plug rack further includes connector, is connected between the more support ribs by the connector.
Preferably, the support rib includes the first support rib and the second support rib, and more first support ribs surround institute
It states proximal end fixing piece to be evenly arranged, more second support ribs are evenly arranged around the distal end fixing piece；Wherein, it is described more
One end of the first support rib of root is connect with the proximal end fixing piece, the other end and the connector of more first support ribs
One end connection；One end of more second support ribs is connect with the distal end fixing piece, more second support ribs
The other end is connect with the other end of the connector；Two connectors of arbitrary neighborhood are connected.
Preferably, the connector includes the second connecting rod of more head rods and Duo Gen, the head rod
One end is connect with one end of second connecting rod；The other end of first support rib and the head rod and/or institute
State the connection of the second connecting rod；The other end of second support rib connects with the head rod and/or second connecting rod
It connects.
Preferably, the other end of the head rod is connect with the other end of second connecting rod.
Preferably, the other end of the head rod connect described second respectively with the other end of second connecting rod
Support rib.
Preferably, the plug rack further includes third support rib, is set between the first support rib described in any adjacent two
Put a third support rib；One end of the third support rib is connect with the proximal end fixing piece, the third support rib
The other end connect respectively with the head rod and second connector.
Preferably, one or more fixed structures, one end connection of the fixed structure are provided on the plug rack
First support rib, the other end are directed away from the direction extension of the axis of the plug rack；When the distal end fixing piece leans on
During the nearly proximal end fixing piece, the fixed structure is located at the position of the non-peripheral surface of the plug rack；When the distal end is consolidated
When determining part far from the proximal end fixing piece, the fixed structure is located at the position of the peripheral surface of the plug rack.
Preferably, the distal end fixing piece includes the hanging ring with centre bore, and the centre bore forms the through-hole.
Preferably, the width of the first inner chamber is less than the width of the distal end fixing piece.
Preferably, the distal end fixing piece has the second inner chamber of perforation, and the width of the second inner chamber is near less than described
Hold the width of fixing piece.
Preferably, second distal end of the push hollow tube is connect with the proximal end fixing piece thread fitting.
Preferably, the traction body is medical guidewire.
Compared with prior art, left atrial appendage occlusion system, occluder for left auricle and its delivery instrument of the invention have as follows
Advantage：
Firstth, the both ends of plug rack are connected a fixing piece by the present invention respectively, wherein the distal end positioned at distal end is fixed
Part can not only shorten the axial length of plug rack in this way with relative to the proximal end kinematic mount of proximal end, so as to
Reduce length when assembled, and then reduce the length of conveyer, can so save cost, reduce surgical procedure difficulty, shorten
Operation time.
Secondth, when the proximally facing kinematic mount of the distal end fixing piece of the present invention, in addition to plug rack can be shortened
Outside axial length, the outer diameter of plug rack on the one hand can be also reduced, by least part weight of plug rack during in order to discharge
New be recycled in delivery sheath is positioned and is discharged again, on the other hand so that the fixed structure on plug rack is fixed in distal end
It may be located remotely from left auricle of heart inner wall under the drive of part, avoid the muscle injury tissue in resetting, removal process, it is ensured that recycling behaviour
The safety and reliability of work.
Description of the drawings
Fig. 1 is the structure diagram of left atrial appendage occlusion system that the present invention is provided according to an embodiment；
Fig. 2 is the partial schematic diagram of left atrial appendage occlusion system shown in FIG. 1, wherein plug rack is omitted；
Fig. 3 a are structure diagram of the present invention according to the occluder for left auricle distal end that an embodiment is provided when constrained；
Fig. 3 b are the structure diagrams when occluder for left auricle distal end that the present invention is provided according to an embodiment is released；
Fig. 3 c are the structure diagrams that the conveyer that the present invention is provided according to an embodiment withdraws occluder for left auricle；
Fig. 4 is the structure diagram of plug rack that the present invention is provided according to an embodiment；
Fig. 5 is the partial schematic diagram of left atrial appendage occlusion system that the present invention is provided according to an embodiment, wherein being omitted
A part of plug rack；
Fig. 6 is the structural representation that the distal end fixing piece that the present invention is provided according to an embodiment is connected with plug rack
Figure；
Fig. 7 is the structure diagram of distal end fixing piece that the present invention is provided according to preferred embodiment.
[the reference numerals are as follows]：
100- occluder for left auricle；
110- plug racks；
The first proximal ends of 111-；The first distal ends of 112-；113- fixed structures；
114- support ribs；
The first support ribs of 1141-；The second support ribs of 1142-；
115- connectors；
1151- head rods；The second connecting rods of 1152-；
116- third support ribs；
120- proximal ends fixing piece；
130- distal ends fixing piece；
131- mounting holes；132- hanging rings；133- mounting holes；134- surface grooves；
200- conveyers；
210- pushes hollow tube；
The second distal ends of 211-；
220- traction bodies；
300- delivery sheaths.
Specific embodiment
To make the purpose of the present invention, advantages and features clearer, below in conjunction with 1~7 pair of left side proposed by the present invention of attached drawing
The various embodiments of atrial appendage occlusion system, occluder for left auricle and its conveyer are described in further detail.It is it should be noted that attached
Figure is only real conveniently, lucidly to aid in illustrating the present invention using very simplified form and using non-accurate ratio
Apply the purpose of example.
As used in the specification and the appended claims, singulative "a", "an" and "the" includes
Plural reference, in addition in addition non-content explicitly points out.Such as used in the specification and the appended claims, term "or"
It is typically used with including the meaning of "and/or", in addition in addition non-content explicitly points out.Term " proximal end " is typically
Refer to close to one end of left auricle of heart oral area, " distal end " refers to one end far from left auricle of heart oral area.The same or similar attached drawing in attached drawing
Label represents the same or similar component.
It is the structure diagram of the left atrial appendage occlusion system of one embodiment of the invention referring initially to Fig. 1, the left auricle of heart envelope
Stifled system includes occluder for left auricle 100 and conveyer 200.The occluder for left auricle 100 includes plug rack 110, proximal end
Fixing piece 120 and distal end fixing piece 130.The conveyer 200 includes push hollow tube 210 and traction body 220.
The plug rack 110 has opposite first proximal end, 111 and first distal end 112, first proximal end 111 with it is near
End fixing piece 120 is connected, and first distal end 112 is connected with distal end fixing piece 130.The proximal end fixing piece 120 and remote
Hold fixing piece 130 simultaneously preferably coaxially arranged along the axially spaced-apart setting of plug rack 110.It is described push hollow tube 210 have with
The second distal end 211 that proximal end fixing piece 120 matches, to realize that push hollow tube 210 is detachably connected with plug rack 110
It connects.
In addition, the traction body 220 is for detachably connectable with distal end fixing piece 130.Specifically, such as Fig. 2 institutes
Show, the traction body 200 is U-shaped to pass through the inner cavity for sending push hollow tube 210 and proximal end fixing piece 120, and blind end passes through remote
It holds the side wall of fixing piece 130 and is connected with distal end fixing piece 130, push hollow tube 210 is stretched out in openend, in assembling,
Can one end of the traction body 220 first be penetrated to the side wall of distal end fixing piece 130, and further be pierced by distal end fixing piece 130
Another opposing sidewalls, then the both ends of traction body 220 are passed through into proximal end fixing piece 120 and push hollow tube 210.It is thus, sharp
Distal end fixing piece 130 can be pulled to be moved relative to proximal end fixing piece 120 with traction body 220, so as to adjust the of plug rack 110
One distal end 112 relative to the first proximal end 111 position.
Particularly, as shown in Figure 3a, when pulling traction body 220 is moved to 111 direction of the first proximal end of plug rack 110
When, a part of plug rack 110 being connected with distal end fixing piece 130 can be enabled to be recessed inwardly, and then shorten plug rack 110 along axis
To length, and so that the length that is assembled in delivery sheath 300 of plugging device will not be long, thus, be conducive to select relatively short
Delivery sheath 300 convey plugging device, to save conveying cost, reduce conveying operations difficulty.Herein, for the ease of retouching
It states, a part of plug rack 110 being connected with proximal end fixing piece 120 is defined as first part, and will be with distal end fixing piece 130
Connected a part of plug rack 110 is positioned as second part, similarly hereinafter.More particularly, the of the plug rack 110 being recessed inwardly
One distal end 112 also enables the outer diameter of plug rack 110 accordingly be reduced, and the outer diameter of diminution is conducive to resetting plugging device.
Specifically, the release process of the occluder for left auricle 100 of the present embodiment is as follows：
First, channel is established in human body by delivery sheath 300；Later, occluder for left auricle 100 is packed into conveying sheath
In pipe 300, and using with the push hollow tube 210 that the proximal end fixing piece 120 of plug rack 110 is connected by occluder for left auricle
100 push to the distal end release of delivery sheath 300.During release：Expansion is released automatically in advance for the first part of the plug rack 110
It puts；After the completion of first part release positioning, as shown in Figure 3b, extraction traction body 220 makes second of plug rack 110
Divide rebound release；After the second part discharges positioning completion, as shown in Figure 3c, push hollow tube 210 and proximal end are released
The connection of fixing piece 120, and delivery sheath 300 and push hollow tube 210 are withdrawn, it is final to realize releasing for occluder for left auricle 100
It puts.
Wherein, before the second part release of the plug rack 110, once operator has found the releasing position of plugging device
It is wrong, such as implantation position is too deep, excessively shallow or crooked, operator can at least realize the recycling of plugging device by the following two kinds mode
And repositioning：
Position of the first way directly to adjust plug rack 110：It keeps proximal end fixing piece 120 static, and passes through and lead
Draw body 220 and drive the movement of 130 proximally facing 120 direction of fixing piece of distal end fixing piece, further to shrink 110 (this of plug rack
In the process, if it is possible that, can also release the fixed relationship between plug rack 110 and left auricle of heart inner wall, such as fitting, anchoring are solid
Determine relationship), and then under the push of push hollow tube 210, position of the adjustment plug rack 110 in left auricle of heart；When closure branch
After the position adjustment of frame 110, extraction traction body 220 can make distal end fixing piece 130 in the natural resiliency of plug rack 110
Spring back to that certain position is static under power effect, so as to fulfill plugging device recycling and repositioning (it should be noted that in rebound
In the process, the plug rack 110 can also restore the fixed relationship between left auricle of heart inner wall, so as to which plug rack 110 be consolidated
Determine, such as the rebound with second part, being anchored on plug rack 110 contacts and be pierced into the left heart under the drive of second part
Ear interior wall tissue, conversely, with the contraction of second part, the anchoring being pierced into advance can detach the left heart under the drive of second part
Ear interior wall tissue)；
The second way is the position of Indirect method delivery sheath 300：It keeps proximal end fixing piece 120 static, and passes through and lead
Draw body 220 and drive the movement of 130 proximally facing 120 direction of fixing piece of distal end fixing piece, further to shrink plug rack 110, when
Plug rack 110 narrow down to it is suitably sized after, by means of push hollow tube 210 by plug rack 110 part or all
Again it is recycled in delivery sheath 300；Later, after being adjusted when the position of delivery sheath 300, again by push hollow tube
120 push plug racks 110 are discharged in the distal end of delivery sheath 300；During release, as previously mentioned, discharging plug rack 110 successively
First part and second part.
In the present embodiment, after being connect with distal end fixing piece 130, the traction body 220 stretches out the both ends of push hollow tube 210
It is fixed with an external component, the connection mode between structure and traction body 220 and external component for external component does not make spy
Other restriction is removably optimal, promotes the convenience of operation.So, traction body 220 and external structure are released during release
The fixed setting of part simultaneously extracts traction body 220 out, you can releases the connection relation of traction body 220 and distal end fixing piece 130.
In preferred embodiment, one or more fixed structures 113, institute are provided on the outer surface of the plug rack 110
Fixed structure 113 is stated for being pierced into the interior wall tissue of left auricle of heart, plug rack 110 is securely fastened in left auricle of heart, is had
Effect prevents from shifting, it is ensured that fixed strong degree.
In preferred embodiment, the fixed structure 113 can move under the drive of distal end fixing piece 130, and block branch
Before the second part release of frame 110 (when such as traction body 220 pulls distal end fixing piece 130 close to proximal end fixing piece 120),
The tip of the fixed structure 113 is pre- before second part release to avoid fixed structure 113 towards left atrial appendage
The interior wall tissue of left auricle of heart is first contacted and be pierced into, and then avoids pulling out fixed structure 113 when resetting and recycling and damaging flesh
Meat tissue.Moreover, after the second part release of the plug rack 110, (after such as detaching traction body 220, the distal end is fixed
When part 130 is far from proximal end fixing piece 120), the tip of the fixed structure 113 towards left auricle of heart inner wall and be finally pierced into the left heart
Ear inner wall.
The fixed structure 113 is either similar to oneself of the cylinders such as anchoring or diagram of the embodiment of the present invention
Plug rack 110 extends outward and the hangnail of cans.The fixed structure 113 can with the one of plug rack 110 into
Type can also be assembled with 110 phase of plug rack.The quantity of the fixed structure 113 is preferably several, multiple fixed structures 113
In on plug rack 110 can in the same direction or different directions arrangement, such as along 110 circumferentially staggered arrangement of plug rack or together
When it is axial arranged along plug rack 110, specific arrangement mode is arranged as needed by user.
Further, the second distal end 211 of the push hollow tube 210 is realized removable with 120 thread fitting of proximal end fixing piece
Connection is unloaded, for example, second distal end 211 has external screw thread, is matched with the internal thread of proximal end fixing piece 120.In other realities
It applies in example (not shown), second distal end 211 can be separately connected by snap-on, buckle etc. with proximal end fixing piece 120.It is described to push away
The material for sending hollow tube 210 can be metal or nonmetallic, nonmetallic preferably high molecular material.
Further, the traction body 220 is, for example, silk, rope, band etc., and what is preferably used on insertion type medical instrument leads
Silk, seal wire can ensure certain hardness and strength, and convenient for gathering materials on the spot, save material.
It subsequently will be solid to the plug rack 110 of the occluder for left auricle 100 of the present invention, proximal end fixing piece 120 and distal end
The structure for determining part 130 is described in further detail and illustrates, but is not limited to the described structure of following embodiments.
As shown in figure 4, it is the structure diagram of the plug rack 110 of one embodiment of the invention.The plug rack 110 wraps
More support ribs 114 are included, the more support ribs 114 are evenly arranged around the axis of plug rack 110, however the present invention includes
But it is not limited to support rib 114 to be evenly arranged around plug rack 110.One end of the more support ribs 114 and proximal end fixing piece
120 are connected, and the other end is connected with distal end fixing piece 130, to form the plug rack 110 of caged.
In order to promote the structural strength of plug rack 110, the plug rack 110 further includes connector 115, described more
It is connected between support rib 114 by connector 115.Thus, through along the circumferentially disposed connector 115 of plug rack 110
The circumferential strength of plug rack 110 is enhanced, reduces the risk that single support rib is easily broken off.
In an embodiment of the present invention, the support rib 114 includes the first support rib 1141 and the second support rib 1142.Institute
More first support ribs 1141 are stated to arrange around proximal end fixing piece 120, and one end of more first support ribs 1141 with it is near
End fixing piece 120 is connected.More second support ribs 1142 are arranged, and described more second around distal end fixing piece 130
One end of support rib 1142 is connected with distal end fixing piece 130.The other end connection connection of more first support ribs 1141
One end of part 115, the other end of the other end connection connector 115 of more second support ribs 1142, and two neighboring company
Fitting 115 is connected.
In an embodiment of the present invention, the connector 115 includes 1151 and second connecting rod 1152 of head rod, institute
The one end for stating head rod 1151 is connected with one end of the second connecting rod 1152.
(not shown) in one embodiment, the other end of the head rod 1151 are another with the second connecting rod 1152
One end is connected, to form cricoid connector 115.Preferably, the other end of more first support ribs 1141 is first
Connector 115 is connected at connecting rod 1151 and the connecting portion of the second support tube 1152.Preferably, more second support ribs
1142 other end connects connector 115 equally at the connecting portion of 1151 and second support tube 1152 of head rod.
In another embodiment, as shown in figure 4, the other end of the head rod 1151 and the second connecting rod 1152
The other end connect second support rib 1142 respectively, and connected two second support ribs 1142 are adjacent.In Fig. 4, often
Two second support ribs 1141 are evenly distributed around distal end fixing piece 130 for one group, certainly, in other embodiments, second
Support bone 1141 may not be it is evenly distributed, the present invention it is without limitation.
In preferred embodiment, as shown in figure 4, the plug rack 110 further includes third support rib 116, any adjacent two
A piece third support rib 116 is set between first support rib 1141.One end of the third support rib 116 and proximal end fixing piece
120 are connected, and the other end is connected with two adjacent connections 115, further enhances the structural strength of plug rack 110.Institute
It is preferably y-type structure to state third support rib 116, and the main body of the y-type structure is connected with proximal end fixing piece 120, the Y types knot
The connector 115 adjacent with two is connected respectively for the Liang Ge branches of structure.Using the third support rib 116 of y-type structure, ensuring
Under the premise of structural strength, structure is relatively easy.
In addition, according to embodiment illustrated in fig. 4, the other end of 1151 and second connecting rod 1152 of head rod
It is connecting at the second support rib 1142, is also curling into hangnail outward, the hangnail forms fixed structure 113.It is highly preferred that
First support rib 1141 is additionally provided with the anchoring for being integrally formed or additionally assembling with the position that connector 115 is connected, with
Form fixed structure 113.One end of the fixed structure 113 connects the first support rib 1141, and the other end is directed away from blocking branch
The direction extension of the axis of frame 110；When the distal end fixing piece 130 is close to proximal end fixing piece 120, the fixed structure 113
Positioned at the position of the non-peripheral surface of plug rack 110, such as positioned at the distal end of plug rack 110；When the distal end fixing piece 130
During far from proximal end fixing piece 120, the fixed structure 113 is located at the position of the peripheral surface of plug rack 110.The hangnail and anchor
It is fixed both to have set together, a setting can also be selected.
As shown in Fig. 2, the proximal end fixing piece 120 have for traction body 220 by first inner chamber, the first inner chamber
Penetrate through proximal end fixing piece 120.The shape of the first inner chamber is not limited to the circle in figure, it is main regard push hollow tube 210 it
Depending on the shape of second distal end 211.Preferably, the width of the first inner chamber of the proximal end fixing piece 120 is less than distal end fixing piece
130 width penetrates first inner chamber under the pulling of traction body 220 to avoid distal end fixing piece 130, influences to operate.For example, institute
Distal end fixing piece 130 is stated as a cylinder, the diameter of the cylinder is more than the width of first inner chamber.If the distal end fixing piece
130 have the second inner chamber of perforation, then the width of the second inner chamber is less than the width of proximal end fixing piece 120, to avoid proximal end
Fixing piece 120 penetrates the second inner chamber of distal end fixing piece 130.
In the present invention, the first inner chamber has first axle, is provided with through-hole on the distal end fixing piece 130, institute
That states traction body 220 penetrates the through-hole to realize the traction to distal end fixing piece 130, and the through-hole has second axis, when
When the first axle is parallel with the second axis, the quantity of the through-hole is two, when the first axle and described the
When two axis are vertical, the quantity of the through-hole is at least one.Certainly, those skilled in the art are it should be appreciated that originally
It is absolute parallel or vertical in signified parallel or vertical non-mathematics geometrical relationship in invention, but generally in parallel or vertical
Position relationship.
In one embodiment of the invention, the through-hole is the peace being opened on the distal end fixing piece 130 on side wall
Hole 131 is filled, the mounting hole 131 preferably radially runs through distal end fixing piece 130.The traction body 220 passes through proximal end fixing piece
120 first inner chamber across the mounting hole 131 on distal end fixing piece 130, realizes the work of traction body 220 and distal end fixing piece 130
Dynamic connection.The mounting hole 131 it is conveniently of circular shape, and diameter be more than traction body 220 width.
In another embodiment of the present invention, it is described as shown in figure 5, the distal end fixing piece 130 includes hanging ring 132
Hanging ring 132 is set to distal end fixing piece 130 close to one end of proximal end fixing piece 120.The through-hole is on the hanging ring 132
Heart hole, so that traction body 220 passes through, traction body 220 can be realized in the centre bore of hanging ring 132 and the activity of distal end fixing piece 130 connects
It connects.Compared to connection mode shown in Fig. 2, connection mode shown in fig. 5 is more conducive to traction body 220 and successfully extracts distal end out
Fixing piece 130, this is because widths affect of the depth of mounting hole shown in Fig. 2 131 by distal end fixing piece 130, width is bigger,
The depth of mounting hole 131 is deeper, can increase the frictional resistance between traction body 220 and mounting hole 131 in this way, influence traction body
220 slip.However, the depth of the centre bore of hanging ring 132 shown in fig. 5 depends on hanging ring 132 thickness of itself, if may,
In the case where not influencing intensity, the thickness of hanging ring 132 can be designed smaller, so the friction between traction body 220 and hole
Resistance is also small, it is easier to slide.The quantity of the hanging ring 132 is not limited to one shown in figure, can also set separately
2 or 2 or more, to enhance reliability.
With continued reference to Fig. 5, one end of the distal end fixing piece 130 is provided with conical projections, and the hanging ring 132 is just set
In the top of the conical projections.
In other embodiments, the through-hole can also be a pair longitudinally opened up along the axis of distal end fixing piece 130
Mounting hole, the present invention is not limited the direction that opens up of through-hole, as long as traction body can be realized to the traction of distal end fixing piece
It can be with.
As shown in fig. 6, for the second support rib 1142 on the first of plug rack 110 the distal end 112 is avoided to wind, it is described remote
It holds and offers the multiple mounting holes 133 penetrated through with the second inner chamber of distal end fixing piece 130 on the side wall of fixing piece 130, it is described more
A mounting hole 133 circumferentially arranges.And then one end of second support rib 1142 is penetrated after mounting hole 133 with distally fixing
The winding of part 130 binding is welded and fixed.Here, the distal end fixing piece 130 is, for example, a shell structure, the shell structure back of the body
One end open from hanging ring 132, other end closing.
The distal end fixing piece 130 can separately connect the second support rib 1142 by mode shown in Fig. 7, specifically, described
Circumferentially distributed multiple surface grooves 134 are offered in the cavity wall of the second inner chamber of distal end fixing piece 130, so that the second support rib
1142 one end is solderable or is bonded or is riveted in surface groove 134.
Same reason, the proximal end fixing piece 120 is such also similar to distal end fixing piece 130, and setting is corresponding solid
Determine hole or surface groove, its one end with the first support rib 1141 is mutually fixedly connected, here, the present invention no longer narration in detail, tool
Body is seen shown in above-described embodiment or figure.
In this present embodiment, the plug rack 100 is self-expanding structure, and material is preferably elasticity or super-elasticity material
Material, the more preferably elastic material with shape memory function.In addition, it is also covered on the outer surface of the plug rack 110
Film, the material of the film is high molecular material.In addition, the material of the proximal end fixing piece 120 and distal end fixing piece 130 is preferred
For biocompatible materials.
It, can also be by grid list since the plug rack of the present invention is not limited to the frame structure disclosed in above-described embodiment
The frame structure that member is formed, therefore the present invention does not require the frame structure of plug rack particularly, as long as its characteristic expires
The demand of the foot present invention.In addition, the proximal end is fixed and distal end fixing piece does not limit to the cylinder of diagram, can separately be made
The structure of other shapes.In addition, the distal end fixing piece is not limited to the shell structure or entity knot of one end open
Structure.Moreover plug rack of the invention is not limited to mutually assemble realization with connector by support rib, it can also be for example, by laser
Cutting processing is realized.
Compared with prior art, left atrial appendage occlusion system, occluder for left auricle and its delivery instrument of the invention have as follows
Advantage：
Firstth, the both ends of plug rack are connected a fixing piece by the present invention respectively, wherein the distal end positioned at distal end is fixed
Part can be located relatively at the proximal end kinematic mount of proximal end, can not only shorten the axial length of plug rack in this way, so as to subtract
Small length when assembled, and then reduce the length of delivery sheath, cost can be so saved, reduces surgical procedure difficulty, is shortened
Operation time.
Secondth, when the proximally facing kinematic mount of the distal end fixing piece of the present invention, in addition to plug rack can be shortened
Outside axial length, the outer diameter of plug rack on the one hand can be also reduced, by least part weight of plug rack during in order to discharge
It is newly recycled in delivery sheath, then is positioned and discharged, on the other hand so that the fixed structure on plug rack is solid in distal end
Determine to may be located remotely from left auricle of heart inner wall under the drive of part, avoid the muscle injury tissue in resetting, removal process, it is ensured that recycling
The safety and reliability of operation.
Third, the present invention only constrain plug rack by traction body, simple in structure plug rack to be enabled to shrink, recycling behaviour
Facilitate.
Foregoing description is only the description to present pre-ferred embodiments, not to any restriction of the scope of the invention, this hair
Any change, the modification that the those of ordinary skill in bright field does according to the disclosure above content, belong to the protection of claims
Range.
Claims (16)
1. a kind of occluder for left auricle, which is characterized in that including：
Plug rack has the first opposite proximal end and the first distal end；
Proximal end fixing piece is connect with first proximal end；And
Distal end fixing piece is arranged at intervals with the proximal end fixing piece and is connect with the described first distal end；
Wherein, it is provided with through-hole on the distal end fixing piece, the proximal end fixing piece has a first inner chamber of perforation, and described first
Inner cavity has first axle, and the through-hole has second axis, described when the first axle is parallel with the second axis
The quantity of through-hole is two, and when the first axle is vertical with the second axis, the quantity of the through-hole is at least one.
2. occluder for left auricle as described in claim 1, which is characterized in that the plug rack includes more support ribs, institute
The axis that more support ribs are stated around the plug rack is arranged；One end of the more support ribs connects with the proximal end fixing piece
It connects, the other end of the more support ribs is connect with the distal end fixing piece.
3. occluder for left auricle as claimed in claim 2, which is characterized in that the plug rack further includes connector, described
It is connected between more support ribs by the connector.
4. occluder for left auricle as claimed in claim 3, which is characterized in that the support rib includes the first support rib and second
Support rib, more first support ribs are evenly arranged around the proximal end fixing piece, and more second support ribs surround institute
Distal end fixing piece is stated to be evenly arranged；
Wherein, one end of more first support ribs is connect with the proximal end fixing piece, more first support ribs it is another
One end is connect with one end of the connector；One end of more second support ribs is connect with the distal end fixing piece, described
The other end of more second support ribs is connect with the other end of the connector.
5. occluder for left auricle as claimed in claim 4, which is characterized in that the connector include more head rods and
More second connecting rods, one end of the head rod are connect with one end of second connecting rod；First support rib
The other end connect with the head rod and/or second connecting rod；The other end of second support rib with it is described
Head rod and/or second connecting rod connection.
6. occluder for left auricle as claimed in claim 5, which is characterized in that the other end of the head rod and described the
The other end connection of two connecting rods.
7. occluder for left auricle as claimed in claim 5, which is characterized in that the other end of the head rod and described the
The other end of two connecting rods connects second support rib respectively.
8. occluder for left auricle as claimed in claim 5, which is characterized in that the plug rack further includes third support rib,
A piece third support rib is set between the first support rib described in any adjacent two；One end of the third support rib and institute
Proximal end fixing piece connection is stated, the other end and the head rod and second connector of the third support rib connect respectively
It connects.
9. occluder for left auricle as described in claim 1, which is characterized in that be provided with one or more on the plug rack
Fixed structure, one end of the fixed structure connect first support rib, and the other end is directed away from the axis of the plug rack
The direction extension of line；
When the distal end fixing piece is close to the proximal end fixing piece, the fixed structure is located at the non-periphery of the plug rack
The position in face；
When the distal end fixing piece is far from the proximal end fixing piece, the fixed structure is located at the peripheral surface of the plug rack
Position.
10. occluder for left auricle as described in claim 1, which is characterized in that the distal end fixing piece includes having centre bore
Hanging ring, the centre bore forms the through-hole.
11. occluder for left auricle as described in claim 1, which is characterized in that the width of the first inner chamber is less than described remote
Hold the width of fixing piece.
12. occluder for left auricle as described in claim 1, which is characterized in that the distal end fixing piece has the second of perforation
Inner cavity, the width of the second inner chamber are less than the width of the proximal end fixing piece.
13. a kind of conveyer of occluder for left auricle for as described in any one of claim 1 to 12, which is characterized in that
Including；Push hollow tube and traction body；The push hollow tube has the second distal end to match with the proximal end fixing piece,
To realize that the push hollow tube and the plug rack are detachably connectable；The traction body is used to penetrate described at least one
A through-hole is simultaneously detachably connectable with the distal end fixing piece.
14. conveyer as claimed in claim 13, which is characterized in that it is described push hollow tube second distal end with it is described
Proximal end fixing piece thread fitting connection.
15. conveyer as claimed in claim 13, which is characterized in that the traction body is medical guidewire.
16. a kind of left atrial appendage occlusion system, which is characterized in that including the left auricle of heart as described in any one of claim 1 to 12
Plugging device and the conveyer as described in any one of claim 13 to 15.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611218481.9A CN108236479A (en) | 2016-12-26 | 2016-12-26 | Left atrial appendage occlusion system, occluder for left auricle and its conveyer |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611218481.9A CN108236479A (en) | 2016-12-26 | 2016-12-26 | Left atrial appendage occlusion system, occluder for left auricle and its conveyer |
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| Publication Number | Publication Date |
|---|---|
| CN108236479A true CN108236479A (en) | 2018-07-03 |
Family
ID=62701474
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201611218481.9A Pending CN108236479A (en) | 2016-12-26 | 2016-12-26 | Left atrial appendage occlusion system, occluder for left auricle and its conveyer |
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| CN (1) | CN108236479A (en) |
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| CN110934664A (en) * | 2018-09-25 | 2020-03-31 | 先健科技(深圳)有限公司 | Heart valve |
| WO2020063348A1 (en) * | 2018-09-29 | 2020-04-02 | 上海微创医疗器械（集团）有限公司 | Left atrial appendage occluder and left atrial appendage occlusion system |
| CN110974316A (en) * | 2019-11-19 | 2020-04-10 | 先健科技(深圳)有限公司 | Plugging device |
| WO2021082974A1 (en) * | 2019-10-28 | 2021-05-06 | 上海微创医疗器械（集团）有限公司 | Medical instrument |
| WO2022127354A1 (en) * | 2020-12-17 | 2022-06-23 | 先健科技(深圳)有限公司 | Occluder and occlusion system |
| WO2023087497A1 (en) * | 2021-11-18 | 2023-05-25 | 河北省胸科医院 | Stent occlusion umbrella for pleural fistula |
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| WO2023087497A1 (en) * | 2021-11-18 | 2023-05-25 | 河北省胸科医院 | Stent occlusion umbrella for pleural fistula |
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Effective date of registration: 20210402 Address after: Room 911, building 1, No. 1601, Zhangdong Road, China (Shanghai) pilot Free Trade Zone, Pudong New Area, Shanghai, 201203 Applicant after: Shanghai Zuoxin Medical Technology Co.,Ltd. Address before: 201 203 No. 501, Newton Road, Zhangjiang High-tech Park, Pudong New Area, Shanghai Applicant before: SHANGHAI MICROPORT MEDICAL (Group) Co.,Ltd. |
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Application publication date: 20180703 |