CN103654883A - Plugging device with locking mechanism - Google Patents

Plugging device with locking mechanism Download PDF

Info

Publication number
CN103654883A
CN103654883A CN201310659952.XA CN201310659952A CN103654883A CN 103654883 A CN103654883 A CN 103654883A CN 201310659952 A CN201310659952 A CN 201310659952A CN 103654883 A CN103654883 A CN 103654883A
Authority
CN
China
Prior art keywords
locking
occluder
end
locking member
section
Prior art date
Application number
CN201310659952.XA
Other languages
Chinese (zh)
Other versions
CN103654883B (en
Inventor
陈贤淼
刘香东
陈杰
张智伟
Original Assignee
先健科技(深圳)有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 先健科技(深圳)有限公司 filed Critical 先健科技(深圳)有限公司
Priority to CN201310659952.XA priority Critical patent/CN103654883B/en
Publication of CN103654883A publication Critical patent/CN103654883A/en
Application granted granted Critical
Publication of CN103654883B publication Critical patent/CN103654883B/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022Occluding by internal devices, e.g. balloons or releasable wires
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022Occluding by internal devices, e.g. balloons or releasable wires
    • A61B17/12027Type of occlusion
    • A61B17/12031Type of occlusion complete occlusion
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022Occluding by internal devices, e.g. balloons or releasable wires
    • A61B17/12099Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder
    • A61B17/12122Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder within the heart
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/0057Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect
    • A61B2017/00575Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect for closure at remote site, e.g. closing atrial septum defects
    • A61B2017/00606Implements H-shaped in cross-section, i.e. with occluders on both sides of the opening

Abstract

The invention relates to a plugging device with a locking mechanism. The plugging device with the locking mechanism comprises a near-end plugging unit, a far-end plugging unit connected with the near-end plugging unit, a fastener arranged at the near end of the near-end plugging unit, and a locking mechanism. A grid frame is arranged on the far-end plugging unit. The fastener is provided with a passageway which is communicated with the near-end plugging unit. The locking mechanism comprises a locking screw and a locking piece, wherein the locking piece is connected with the locking screw, the locking piece and the locking screw are movably arranged in a space defined by the far-end plugging unit and the near-end plugging unit, the locking screw penetrates through the grid frame and the passageway, the locking screw is pulled to drive the far-end plugging unit to compress the near-end plugging unit, and the locking piece moves out of the passageway and is stopped by the fastener. After being released, the plugging device is fixedly attached to the two sides of a damaged portion only by pulling the locking screw and the locking piece to retrain the two plugging units, and the plugging device is simple in structure and easy to operate. The plugging units are restrained by the locking screw instead of a rigid connecting rod, and therefore the formed plugging device is good in deformation harmony, and violent beating of the heart is easily harmonized.

Description

带锁定机构的封堵器 Occluder with locking mechanism

技术领域 FIELD

[0001 ] 本发明涉及介入型医疗器械,尤其涉及可用于封堵心脏或血管内缺损的带锁定机构的封堵器。 [0001] The present invention relates to interventional medical devices, particularly to be used for closure of heart defects or locking with intravascular occluder mechanism.

背景技术 Background technique

[0002] 随着介入治疗器械和介入心脏病学的不断发展,经导管介入封堵器微创治疗房间隔缺损、室间隔缺损、动脉导管未闭和卵圆孔未闭等先天性心脏病成为重要方法,同样用介入方式进行血管腔内封堵也是广为接受的治疗手段。 [0002] With the development of interventional therapeutic devices and interventional cardiology, interventional transcatheter occluder minimally invasive treatment of atrial septal defect, ventricular septal defect, patent ductus arteriosus and patent foramen ovale, congenital heart disease as the other important way, in the same manner endovascular interventions for closure is also widely accepted treatment. 现有技术中的封堵器一般包括有两个封堵单元,用来盖住缺损部位的两侧壁的组织,但某些封堵器由于本身的构造以及材料等原因导致它的两个封堵单元之间的收缩力不足,并不能贴紧缺损部位的两侧而影响封堵效果,因此往往在这类封堵器中还设计有用来保持两个封堵单元之间的距离稳定的锁定机构,但是这些带有锁定机构的封堵器都存在某些使用上的缺陷。 Prior art occluder typically comprises two blocking means for covering both sides of the tissue wall defect site, but some of the occluder and due to the construction material itself, as a result of its two seal insufficient contractile force between the blocking means and snapping not affect both the defect site blocking effect, it is often also designed in such occluder for holding the distance between the two stable locking block units It means, with a locking mechanism but these are flawed occluder on some use. [0003] 例如,如图1所示,公开号为US2007/0250115A1的专利申请文献涉及一种封堵器:其包括封堵器本体I和锁定机构,该封堵器本体I是由金属管材激光切割再通过热定型成预定的形状,其中锁定机构的详细构成如图2所示,由连接杆9和漏斗帽4所组成。 [0003] For example, as shown in FIG Publication No. US2007 / 0250115A1 Patent Document application relates to an occluder: I comprising occluder body and locking mechanism, the occluder body I is made of a metal pipe laser restyling cut into a predetermined shape by heat, wherein the locking mechanism of the detailed configuration shown in Figure 2, by the connecting rods 9 and composed of four funnel cap. 封堵器本体I具有远端8和近端3以及它们之间的两个封堵单元,近端3上具有外螺纹并开设有缺口,连接杆9的一端连接在远端8上,另一端上具有锥形部件2,在连接杆9上具有锥形部件2的这一端与输送拉丝5远端的螺纹7连接。 I occluder body having a proximal end and a distal end 8 between the two sealing means and their 3, the proximal end having an external thread 3 and defines a gap, one end of the connecting rod 9 is connected to the distal end 8, and the other end 2 having a tapered member having a tapered end of the member 2 in the connecting rod 9 and the screw conveyor 7 is connected to the distal end of the wire drawing 5. 漏斗帽4中内螺纹形成的内径具有一定的锥度,内径较小的一端连接输送鞘管6,内径较大的一端与带有缺口的近端3相配合。 The inner diameter of the funnel threaded cap 4 is formed has a certain taper, smaller inner diameter end connected to the delivery sheath 6, the inner diameter of the larger proximal end and cooperates with a notch 3. 当需要将递送至预定位置的封堵器收紧时,首先回撤输送拉丝5,使连接杆9上的锥形部件2穿过近端3的内腔,然后操作输送鞘管6使漏斗帽4相对近端3旋紧,由于漏斗帽4内径具有一个锥度,这样在旋紧过程中可使近端3的端口收缩,锥形部件2被卡扣在收缩的端口处,从而可以收紧封堵器本体I的两个端部,使近端3和远端8之间的距离保持稳定。 When it is desired to deliver to a predetermined position of the occluder tightened first conveying retracement drawing 5, the connecting rod having a tapered member 92 on the proximal end through the lumen 3, the operation of the delivery sheath 6 and then the funnel cap 4 relative to the proximal end 3 is screwed, since the inner diameter of the funnel cap 4 has a taper, so that the proximal port can shrink 3, the conical member 2 is snap-fastened during contraction at a port, thereby tightening the seal both end portions of the block body I, a distal end and a proximal end 3 the distance between the stable 8.

[0004] 该封堵器在体内释放后,左右两个封堵单元之间通过锁定机构的约束作用,可以使得封堵器左右两个封堵单元紧密贴合在缺损部位的两侧,但是该锁定机构的设计较为复杂,增加了较多组件,同时锁定机构中需要使用多个螺纹相互配合以达到锁定封堵器的目的,这种锁定机构在人体内操作较为困难,会提高手术操作难度,从而降低手术成功率。 [0004] After releasing the occluder body, between the left and right two units by the restriction effect closure of the locking mechanism can be made about two closure units occluder close contact with both sides of the defect site, but this more complex design of the locking mechanism, larger components increase, while the locking mechanism requires the use of multiple threads cooperate to achieve the purpose of locking the occluder, such a locking mechanism is difficult to operate in the body, increase the difficulty of the surgical procedure, thereby reducing the success rate of surgery. 此外,该锁定机构的连接杆9刚性过大,使得成型后的封堵器本体I变形协调性差,难以协调心脏的剧烈跳动。 In addition, the locking mechanism is too rigid connecting rod 9, so that the occluder body after molding is poor coordination modification I, it is difficult to coordinate the pounding heart.

[0005] 又如,如图3所示,公开号为W02010151510A1的专利申请文献涉及的另一种封堵器:其包括金属框架11、阻流膜13、远端12及近端15、锁环16。 [0005] In another example, shown in Figure 3, Publication No. another occluder Patent Application Publication W02010151510A1 according to: which comprises a metal frame 11, flow blocking film 13, a proximal end 15 and distal end 12, locking ring 16. 金属框架11用于支撑整个封堵器,金属框架11的腰部14提供使用时对缺损部位的封堵张力,阻流膜13覆在金属框架11上用于封堵血流,近端15用于连接和释放封堵器。 A metal frame for supporting the entire closure device 11, the metal frame 11 of the waist 14 is used to provide tension to the closure of the defect site, choke cover film 13 for sealing the blood flow on the metal frame 11, a proximal end 15 for attachment and release occluder. 锁环16的一端连接于远端12上,它用于将金属框架11的两个封堵单元的相对位置固定以防其扩张,近端15和腰部14中心各加工有一个小孔,可供锁环16通过。 One end of the lock ring 16 is connected to the distal end 12, which is used to block the relative positions of the two units of the metal frame 11 is fixed to prevent its expansion, the center 14 and the proximal waist 15 there is formed a small hole each, for 16 by the lock ring. 该封堵器使用时通过输送系统将其放入人体心脏或血管缺损部位,其在释放后两个封堵单元恢复至图3所示的形态,锁环16在自然状态下靠近远端12。 The occluder into which the human cardiac or vascular defect through the delivery system when used, in which the two closure means to return to the release of the embodiment shown in FIG. 3, the locking ring 16 near the distal end 12 in a natural state. 当需要将封堵器的两个封堵单元锁紧改善其成型形态时,可通过拉紧锁环16使之伸展开来,穿过腰部14和近端15中心的小孔,到达近端15的外侧,进而缠绕在近端15上,从而使封堵器左右两个封堵单元贴合缺损部位的两侧并防止鼓起,如图4所示。 When it is desired occluder two locking units occluder improve its molded shape, may be passed through the tension lock ring 16 spread out, through the aperture 15 in the center of the waist 14 and a proximal end, to the proximal end 15 the outside, and then wound on a proximal end 15, so that the right and left occluder two closure units bonded to both sides of the defect and to prevent bulging, as shown in FIG.

[0006] 这种锁定机构虽然手术操作简单,但由于其中的锁环16为一卷曲的金属丝,它是靠弹性的作用自动缠绕在封堵器近端15上,在手术过程中或者术后容易发生缠绕不紧而脱离的情况,从而造成锁定作用失效;而且锁环16局部不能很好地贴紧封堵器的近端15,锁环16局部过分突出的部分从而不容易形成内皮爬覆,容易导致血栓的形成。 [0006] Such a locking mechanism, although simple operation, but the locking ring 16 which is a coiled wire, which is wound automatically by the action of the elastic occluder on the proximal end 15, during surgery or after surgery prone wound tight and without departing thereby causing failure of the locking action; and lock ring 16 is not well localized adhesion of the proximal end of the occluder 15, the lock ring 16 partially protrudes over the portion to be formed is not easily climb overlying endothelium , easily lead to thrombosis. 同时锁环16卷曲的金属丝的尾端比较尖锐,所以非常容易造成心脏内组织的损伤。 At the same time the end of the lock ring 16 crimped wire relatively sharp, so it is very likely to cause tissue damage in the heart.

[0007] 综上所述,图1和图2所描述的封堵器使用一根刚性的连接杆9来约束封堵器两端的距离,该方式的锁定机构结构复杂,操作麻烦,容易降低手术成功率,同时该锁定机构的刚性过大,使得成型后的封堵器I变形协调性差,难以协调心脏的剧烈跳动。 [0007] In summary, FIG. 1 and FIG. 2 occluder described using a rigid connecting rods 9 to ends of the occluder distance constraint, the complex structure of the locking mechanism of the embodiment, the operation is troublesome, reducing the easy operation success rate, while the rigidity of the locking mechanism is too large, so that the molded occluder I modification poor coordination, pounding of the heart is difficult to coordinate. 图3和图4所描述的封堵器中的锁环16为一卷曲的金属丝,它的一端固定于远端12上,并可以通过操作穿过另一侧的近端15的中间圆孔,使左右两个封堵单元贴合于缺损的两侧并防止其鼓起。 FIGS. 3 and 4 of the occluder is described in a lock ring 16 is crimped wire, one end of which is fixed to the distal end 12, and the other by operating through the proximal side of the intermediate circular hole 15 the left and right sealing unit bonded to both sides of the defect and to prevent its bulging. 但由于锁环16在近端15的位置过分突出从而造成该区域不容易形成内皮爬覆,容易导致血栓的形成。 However, due to the lock ring 16 at a position projecting over the proximal end region 15 causing the coating is not easily formed endothelial climb, easily lead to thrombosis. 同时锁环16作为一根卷曲的带尖端的金属丝也非常容易造成心脏内组织的损伤。 At the same time as the lock ring 16 with a coiled wire tip is also very easy to damage the heart tissue.

[0008] 此外,以上两种锁定机构也对封堵器自身的结构提出了要求,即封堵器必须具有远端结构来固定锁定机构的一端。 [0008] In addition, two or more types of self-locking mechanism configuration occluder requests, i.e., a distal occluder having a structure must be fixed to one end of the locking mechanism. 这种封堵器的远端结构将增加封堵器的材料用量,其释放的大量金属离子或小分子会增加机体的负担;另外,远端结构与封堵器框架结构不同,两者之间的过渡部分容易产生应力集中,从而增加该处材料断裂的风险;且远端结构突出,即使释放封堵器后也不能完全展开,不仅容易造成对人体心脏内组织的损害,而且也不利于内皮组织爬覆。 Such distal occluder structure will increase the amount of material occluder, the release of a large number of small molecules or metal ions will increase the burden on the body; Further, the structure of the distal end of the occluder different frame structure, between the transition prone to stress concentration, thereby increasing the risk of fracture where the material; and prominent distal structure, even after the release of the occluder can not be fully extended, not only easily lead to tissue damage in the human heart, and is not conducive endothelial organization climb cover.

发明内容 SUMMARY

[0009] 本发明的目的在于提供一种带锁定机构的封堵器,当该封堵器在体内释放后其左右两个封堵单元能通过锁定机构进行收紧,并贴合于缺损部位的两侧。 [0009] The object of the present invention is to provide a closure device with a locking mechanism, for tightening the occluder when the two left and right after releasing the closure body by the lock mechanism unit, and bonded to the defect site both sides.

[0010] 解决本发明的技术问题所采用的技术方案是:提供一种带锁定机构的封堵器,包括近端封堵单元、与所述近端封堵单元相连的远端封堵单元、设于所述近端封堵单元近端的紧固件、以及锁定机构;所述远端封堵单元设有网格框架;所述紧固件具有与所述近端封堵单元相通的通道;所述锁定机构包括锁丝和锁定件,所述锁定件与所述锁丝相连且可动地设于所述远端封堵单元和所述近端封堵单元合围形成的空间内,所述锁丝穿过所述网格框架后穿过所述通道,拉动所述锁丝带动所述远端封堵单元压缩所述近端封堵单元,且把所述锁定件移至所述通道外后,所述锁定件由所述紧固件抵挡。 [0010] Solving the problem of the invention is employed: to provide a tape locking mechanism of the occluder, the occluder includes a proximal section, a distal end and a proximal end blocking unit connected to the sealing unit, sealing means provided on the proximal end of the proximal fastener, and a locking mechanism; said distal occluder element is provided with a grid frame; blocking the fastener having a proximal end in communication with said passage means ; the locking mechanism includes a lock wire and a locking member, said locking member and said lock wire is connected and movably disposed in the distal end of the inner space and sealing means sealing the proximal end of the unit cooperatively define, the said lock wire after passing through the mesh of said frame through passage, pulling the distal end of the lock wire driving means compresses the occluder proximal end closure means and said locking member to move into the channel after the addition, the locking member by the fastener to resist.

[0011 ] 在依据本发明实施例的带锁定机构的封堵器中,所述锁丝包括均与所述锁定件相连的锁定段和牵引段;所述锁定段穿过所述网格框架;所述牵引段穿过所述通道。 [0011] In the locking mechanism in accordance with an embodiment of the present invention, occluder, the lock wire comprises both the locking member and a locking section coupled to the traction section; said locking segment through said grid frame; the traction section through the channel.

[0012] 在依据本发明实施例的带锁定机构的封堵器中,所述锁定件上设有通孔,所述牵引段穿过所述通孔与所述锁定件相连。 [0012] In the locking mechanism in accordance with an embodiment of the present invention, occluder, the locking member is provided with a through hole, said traction member is connected to the section through the locking through hole.

[0013] 在依据本发明实施例的带锁定机构的封堵器中,所述锁定件包括两个锁定球,每个所述锁定球的直径小于所述通道的最小直径,且所述两个锁定球的直径之和大于所述通道的近端直径;所述锁定段的两端分别与一个所述锁定球相连,所述牵引段分为两根,每一根牵引段的一端与一个所述锁定球相连,另一端穿过所述通道;所述封堵器的总高度大于所述锁定段总长度的二分之一。 [0013] In the locking mechanism in accordance with an embodiment of the present invention, occluder, the locking member comprises two locking balls, the locking balls each having a diameter smaller than the smallest diameter of the passage, and the two locking ball diameter greater than the diameter of the proximal end of the channel; the locking end sections are connected to one of said locking ball, pulling the segment is divided into two, one end of each of the traction segment with a said lock balls connected to the other end of the through passage; the obturator is greater than the total height of the lock half of the total length of the segments.

[0014] 在依据本发明实施例的带锁定机构的封堵器中,所述锁定件进一步包括连接在所述牵引段上的调节球;每个调节球的直径均小于所述通道的最小直径,且所述两个调节球的直径之和或者任意一个所述锁定球与任意一个调节球的直径之和均大于所述通道的近端直径;所述封堵器的总高度大于一根所述牵引段上的所述锁定球和所述调节球中的一个与另一根所述牵引段上的所述锁定球和所述调节球中的一个之间的锁丝长度的二分之一。 [0014] In the locking mechanism in accordance with an embodiment of the present invention, occluder, the locking member further comprising a regulator connected to a ball on the traction section; minimum diameter of each ball is less than the diameter of said adjusting channel and adjusting the two balls and the diameter of the ball, or any one of the locking and adjusting any one ball diameter and greater than the diameter of the proximal end of the channel; the total height is greater than the one of the occluder drawing the upper section of said ball and said one locking ball and the other in the traction segment of the locking ball and adjusting one-half the length of the wire between the lock ball in one of said adjusting .

[0015] 在依据本发明实施例的带锁定机构的封堵器中,所述锁定件呈长条形;所述锁定段的一端连接所述锁定件的长边侧,另一端穿过所述网格框架后与所述紧固件的远端相连;所述牵引段的一端连接所述锁定件的短边侧,另一端穿过所述通道;所述封堵器的总高度大于所述锁定段的总长度的二分之一。 [0015] In the locking mechanism in accordance with an embodiment of the present invention, occluder, the locking member elongated strip; end of the locking section is connected to the long side of the locking member, the other end through the after the grid frame is coupled to the distal end of the fastener; end of the pulling section connected to the short side of the locking member, the other end of the through passage; the obturator is greater than the overall height of one-half of the total length of the locking section.

[0016] 在依据本发明实施例的带锁定机构的封堵器中,所述锁定件呈长条形;所述锁定段的两端均连接所述锁定件的长边侧;所述牵引段的一端连接所述锁定件的短边侧,另一端穿过所述通道;所述封堵器的总高度大于所述锁定段的总长度的二分之一。 [0016] In the locking mechanism in accordance with an embodiment of the present invention, occluder, the locking member elongated strip; locking said end sections are connected to the long side of the locking member; said tensioned the short side of the one end connected to the locking member, the other end of the through passage; the obturator is greater than the total height of the lock half of the total length of the segments.

[0017] 在依据本发明实施例的带锁定机构的封堵器中,所述锁定件呈长条形;所述锁定段为闭合结构,在所述锁定件的长边侧穿过所述锁定件;所述牵引段的一端连接所述锁定件的短边侧,另一端穿过所述通道;所述封堵器的总高度大于所述锁定段的总长度的二分之一O [0017] In the locking mechanism in accordance with an embodiment of the present invention, occluder, the locking member elongated strip; said locking segment is closed configuration, through the locking of the long side of the locking member member; traction section end of the short side is connected to the locking member, the other end of the through passage; total height of the obturator is greater than the total length of the locking section of one-half of O

[0018] 在依据本发明实施例的带锁定机构的封堵器中,所述紧固件包括外套筒、以及嵌设在所述外套筒内的内套筒;编织所述网格框架的丝固定在所述内套筒与所述外套筒之间的间隙内。 [0018] In the locking mechanism in accordance with an embodiment of the present invention, the occluder, the fastener comprising an outer sleeve and an inner sleeve embedded in said outer sleeve; knit the mesh frame yarn fixing the gap between the outer sleeve and the inner sleeve.

[0019] 在依据本发明实施例的带锁定机构的封堵器中,所述紧固件还设有与所述通道相通的凹槽;所述锁定件拉出所述通道后收容于所述凹槽内。 [0019] In the locking mechanism in accordance with an embodiment of the present invention, the occluder, the fastener is also provided with a groove communicating with said passage; said locking member received in the channel after the pull-out in the groove.

`[0020] 在依据本发明实施例的带锁定机构的封堵器中,所述封堵器还包括位于所述远端封堵单元和所述近端封堵单元合围形成的空间内的弹性漏斗,所述弹性漏斗的漏斗口朝向远端,所述弹性漏斗通过漏嘴在所述通道的远端与所述通道连通。 `[0020] In the locking mechanism in accordance with an embodiment of the present invention, occluder, the occluder further comprises a sealing means at the distal and proximal end of the resilient element in the space formed by sealing the encirclement funnel, the funnel mouth elastic funnel toward the distal end, the distal end of the elastic funnel in communication with said drain passage through said channel mouth.

[0021] 在依据本发明实施例的带锁定机构的封堵器中,所述近端封堵单元内、所述远端封堵单元内以及所述远端封堵单元与所述近端封堵单元的连接部内均设有阻流膜;且所述近端封堵单元内和所述连接部内的所述阻流膜上设有用于通过所述锁定件的孔。 [0021] In the locking mechanism in accordance with an embodiment of the present invention, occluder, the occluder proximal end of the inner unit, the inner blocking unit and the distal end of the distal end of the proximal end of the sealing unit and blocking inner connecting portions are provided with means blocking flow blocking film; and the proximal end of the occluder within the baffle means and the connection film portion is provided with inner through holes for the locking member.

[0022] 在依据本发明实施例的带锁定机构的封堵器中,所述封堵器由生物相容的高分子材料制成。 [0022] In the locking mechanism in accordance with an embodiment of the present invention, the occluder, the occluder is made of a biocompatible polymer material.

[0023] 与现有技术相比,依据本发明实施例的封堵器在体内释放后,仅需通过拉动锁丝带动远端封堵单元压缩近端封堵单元,并由锁定件卡位即可约束两个封堵单元,使其固定贴合于缺损部位两侧,结构简单且操作简易;相比刚性连接杆,采用锁丝约束封堵单元,使成型后的封堵器变形协调性较好,易于协调心脏的剧烈跳动。 [0023] Compared with the prior art, according to the embodiment of the occluder embodiment of the present invention in vivo upon release, driven only by pulling the lock wire distal occluder proximal end of the compression unit block unit, i.e., by latching the locking member two block units may be bound, it is fixed attached on both sides of the defect site, a simple structure and easy operation; compared to rigid connecting rod, using the lock wire constraint closure means, so that the deformation coordination occluder after molding than well, easier to coordinate heart pounding.

附图说明 BRIEF DESCRIPTION

[0024] 下面将结合附图及实施例对本发明作进一步说明,附图中:[0025] 图1是现有技术中公开号为US20070250115A1的专利申请文献涉及的封堵器的结构示意图; [0024] conjunction with the following drawings and embodiments of the present invention is further illustrated drawings in which: [0025] FIG. 1 is a prior art schematic structure Publication No. US20070250115A1 occluder patent application relates to a document;

[0026] 图2是图1中封堵器的锁定机构的结构示意图; [0026] FIG. 2 is a schematic configuration diagram of a locking mechanism in the closure device;

[0027] 图3是现有技术中公开号为W02010151510A1的专利申请文献涉及的封堵器处于松驰状态时的结构示意图; Schematic structural view of [0027] FIG. 3 is a prior art disclosed in Patent Application No. W02010151510A1 occluder according to the literature in the relaxed state;

[0028] 图4是图3的封堵器中左右两个封堵单元锁紧时的结构示意图; [0028] FIG. 4 is a schematic block two locking units occluder of FIG. 3 at the left and right;

[0029] 图5是依据本发明实施例一的封堵器处于松驰状态时的示意图; [0029] FIG. 5 is a schematic diagram of an embodiment of the occluder is in a relaxed state according to embodiments of the present invention;

[0030] 图6是图5中封堵器处于锁紧状态时的示意图; [0030] FIG. 6 is a schematic view of the locked state of FIG. 5 in an occluder;

[0031] 图7是依据本发明实施例的封堵器的紧固件的剖视图; [0031] FIG. 7 is a sectional view of the fastener according to embodiments of the occluder embodiment of the present invention;

[0032] 图8是图7中的紧固件的一种替换实施的剖视图; [0032] FIG. 8 is a sectional view of an alternative embodiment of the fastener of FIG 7;

[0033] 图9是依据本发明实施例的紧固件和弹性漏斗结合的剖视图; [0033] FIG. 9 is a sectional view of the fastener and the resilient hopper embodiments of the present invention based on binding;

[0034] 图10是依据本发明实施例的具有通孔的锁定件的示意图; [0034] FIG. 10 is a schematic view of the locking member having a through hole in accordance with an embodiment of the present invention;

[0035] 图11是依据本发明实施例的具有凹槽的紧固件的示意图; [0035] FIG. 11 is a schematic view of a fastener having a recess in an embodiment according to the present invention;

[0036] 图12是依据本发明实施例二的封堵器处于松驰状态时的示意图; [0036] FIG. 12 is a schematic view when in the relaxed state occluder according to the second embodiment of the present invention;

[0037] 图13是图12中的封堵器处于一种锁紧状态时的示意图; [0037] FIG. 13 is a schematic view of a locked state in FIG. 12 is an occluder;

[0038] 图14是依据本发明实施例三的封堵器的示意图; [0038] FIG. 14 is a schematic diagram according to a third embodiment of a closure device according to the present invention;

[0039] 图15是依据本发明实施例四的封堵器的示意图; [0039] FIG. 15 is a schematic diagram of the fourth embodiment of the present invention according occluder;

[0040] 图16是依据本发明实施例五的封堵器的示意图; [0040] FIG. 16 is a schematic diagram of the embodiment occluder embodiment of the present invention is based on five;

[0041] 图17是图16中的封堵器中缝合有阻流膜的示意图; [0041] FIG. 17 is a schematic flow blocking film 16 are sewn occluder;

[0042] 图18是图16中的封堵器的锁定件的局部示意图; [0042] FIG. 18 is a partial schematic view of the locking member 16 of the occluder;

[0043] 图19是图18中的锁定件的一种替换实施方式的示意图; [0043] FIG. 19 is a schematic view of an alternative embodiment of the embodiment in FIG. 18 of the locking member;

具体实施方式 Detailed ways

[0044] 为了使本发明的目的、技术方案及优点更加清楚明白,以下结合附图及实施例,对本发明进行进一步详细说明。 [0044] To make the objectives, technical solutions and advantages of the present invention will become more apparent hereinafter in conjunction with the accompanying drawings and embodiments of the present invention will be further described in detail. 应当理解,此处所描述的具体实施例仅仅用以解释本发明,并不用于限定本发明。 It should be understood that the specific embodiments described herein are only intended to illustrate the present invention and are not intended to limit the present invention.

[0045] 为了更加清楚地描述封堵器的结构,此处限定术语“远端”、“近端”、以及“封堵器的总高度”,这些术语为介入医疗器械领域惯用术语。 [0045] In order to more clearly describe the structure of the occluder, defined herein the term "distal", "proximal" and "total height occluder", as these terms are conventional terms interventional surgical field. 具体而言,“远端”表示手术过程中远离操作者的一端,“近端”表示手术过程中靠近操作者的一端;“封堵器的总高度”表示封堵器在释放后,处于自由状态或松弛状态时封堵器的远端到封堵器的近端之间的距离或高度。 Specifically, the "distal end" indicates an end of the operator away from the surgical procedure, "proximal" means a surgical procedure near an end of the operator; "total height of the occluder" indicates occluder after releasing, consisting in state or the relaxed state of the distal end of the occluder to a height or distance between the proximal end of the occluder.

[0046] 下面将结合附图和多个具体实施例对本发明做进一步详细说明。 [0046] The following specific examples will be described in further detail in conjunction with the accompanying drawings of the present invention and a plurality.

[0047] 图5示出了依据本发明实施例一的封堵器20的示意图,该封堵器20包括锁定机构、设置在远端26的远端封堵单元42、设置在近端27的近端封堵单元43、以及设于近端封堵单元43近端的紧固件23,紧固件23具有与近端封堵单元43相通的通道24。 [0047] FIG. 5 shows a schematic diagram of an embodiment 20 of the present embodiment of the invention according to the occluder, the occluder 20 includes a locking mechanism 26 disposed at the distal end of the distal occluder element 42, 27 is provided at the proximal end of plugging the proximal end section 43, and a fastener 43 provided on the proximal end of the proximal end of the blocking unit 23, the fastener 23 has a proximal end blocking units 43 communicating passage 24.

[0048] 远端封堵单元42与近端封堵单元43延伸相连,均可由超弹性材料制成的编织网框架41构成。 [0048] The distal end of the blocking unit 42 is connected with the proximal end 43 extending sealing means, can be made of a woven mesh frame 41 composed of a superelastic material. 编织网框架41可为采用高分子等材料通过编织、管材切割、注塑成型等方式制成网状结构。 Woven mesh frame 41 can be made of a mesh structure by weaving the use of polymer materials and the like, pipe cutting, injection molding or the like. 在本发明的实施例中,当远端封堵单元42由编织丝编织而成时,网格框架41a可为远端封堵单元42的一部分,例如,网格框架41a是上述编织网框架41的一部分;或者网格框架41a可为连接在远端封堵单元42上的一部分附加编织结构体。 In an embodiment of the present invention, when the distal closure means 42 formed by weaving woven wire mesh 41a of the frame 42 for sealing the distal end portion of the cells, e.g., the above-described grid frame 41a is braided mesh frame 41 part; grid frame 41a or additional woven structure portion 42 of the body unit may be connected at the distal occluder. 本领域的普通技术人员可以根据需要或封堵器的类型选择适合的网格框架41a。 Those of ordinary skill in the art can choose the type of grid frame 41a according to need or occluder.

[0049] 因封堵器的自身结构、材料或热处理工艺等原因容易导致其两个封堵单元之间的收缩力不足,即远端封堵单元42和近端封堵单元43并不能很好地贴紧缺损部位,从而影响封堵效果。 [0049] The reasons occluder own structure, material, or other heat treatment process easily lead to insufficient contractive force between its two sealing units, i.e., a distal end and a proximal closure means 42 closure means is not a good 43 snapping the defect site, thus affecting the sealing effect. 为了改善封堵器的封堵效果,需在封堵器上的远端封堵单元42和近端封堵单元43之间增设锁定机构,通过限定封堵器的总高度来使两者贴紧缺损部位。 To improve the sealing effect of the occluder, a distal occluder on the required closure means 42 and a proximal end additional closure means between the locking mechanism 43, defined by the overall height of the occluder to make close contact with both the defect site. 例如,若编织网框架41是由可降解高分子丝编织形成,则因高分子材料与传统的NiTi合金相比,弹性模量较低,弹性范围较小,使编织网框架41定型后并不能很好地保持其预定型形态,此时则需要通过锁定机构来改善上述封堵器在体内的成型性能。 For example, if the frame 41 is a woven mesh formed of woven biodegradable polymer filaments, due to polymer materials compared with conventional NiTi alloys, lower modulus of elasticity, a small elastic range, so that a woven mesh frame 41 after setting and can not type well maintain its predetermined shape, it is necessary at this time to improve the performance of the above-described molded occluder in the body by the locking mechanism.

[0050] 锁定机构包括锁丝25,21 ;以及锁定件50。 [0050] The locking mechanism comprises a locking wire 25,21; 50 and a locking member. 其中,锁定件50与锁丝25,21相连且可动地设于远端封堵单元42和近端封堵单元43合围形成的空间44内(以下称为合围空间);锁丝25穿过网格框架41a,具体而言锁丝25穿过网格框架41a后再次进入上述合围空间内。 Wherein, the locking member 50 is connected with the lock wire 25,21 and may be provided in the distal end of the movable block 44 and a proximal end blocking unit 42 unit 43 cooperatively define a space (hereinafter, referred to surround the space); lock wire 25 passes through the grid frame 41a, specifically, lock wire 25 passes through the grid frame 41a after re-entering the above space encircled. 且锁丝21穿过通道24,拉动锁丝21带动远端封堵单元42压缩近端封堵单元43,且把锁定件50移至通道外后,锁定件50由紧固件23抵挡。 And the lock wire 21 through the passage 24, the lock wire 21 is pulled to drive the distal end of the proximal occluder blocking compression unit 42 unit 43, and the outer passage 50 to move the locking member, the locking member 50 by the fastener 23 to withstand.

[0051] 例如,编织网框架41为整体网状结构,具有多个网孔,因此可将编织网框架41远端的一部分作为网格框架41a。 [0051] For example, the frame 41 is integrally woven mesh net structure having a plurality of cells, and therefore may be braided mesh grid frame as a frame part 41a of the distal end 41. 锁丝25可从网格框架41a的任意一个网孔穿出到达编织网框架41的外侧,同时又从网格框架41a的另一个不同的网孔穿进返回到网状框架41的内部,即合围空间内部。 Lock wire 25 can be a cell from any piercing grid frame 41a reaches the outside of the braided mesh frame 41, while the other and from different grid frame 41a is returned to the cell through the mesh into the interior of the frame 41, i.e., encirclement internal space. 为了保持受力的均匀性,上述穿进穿出的两个网孔的位置优选位于封堵器20的远端26处位置对称的两个网孔。 In order to maintain the uniformity of the force of the two cells through piercing position into the distal end of the occluder 20 is preferably located at the two symmetrical positions 26 mesh.

[0052] 锁丝包括锁定段25和牵引段21,锁定件50包括两个锁定球22。 [0052] The lock includes a lock segment 25 and the wire pulling section 21, the locking member 50 comprises two locking balls 22. 每个锁定球22均与锁定段25和牵引段21相连,各锁定球22固定在锁丝上,即各锁定球22相对锁丝不可移动。 Each locking ball 22 is connected to the locking segments 25 are tensioned and 21, each locking ball 22 is fixed in the lock wire, i.e. opposite the respective locking balls 22 lock the wire immovable. 每个锁定球22的直径均小于通道24的最小直径,且两个锁定球22的直径之和大于通道24的近端直径;封堵器20的总高度大于锁定段25总长度的二分之一。 Each locking ball 22 has a diameter less than the minimum diameter of the passageway 24, and the diameter of the two locking ball 22 is greater than the diameter of the proximal end of channel 24; the total height of the occluder 20 is greater than the overall length of the locking section 25 of two-thirds One.

[0053] 具体地,锁定段25的两端分别与一个锁定球22相连。 [0053] In particular, the locking end sections 25 and 22 are respectively connected to a locking ball. 牵引段21分为两根,每一根牵引段21的一端与一个锁定球22相连,另一端穿出通道24,并通过输送系统一直延伸到病人的体外,医生可操作牵引段21的体外端来改变锁定球22的相对位置。 Traction segment 21 is divided into two, each of the traction section 21 with one end connected to a locking ball 22, the other end of the piercing channel 24, and extend through the delivery system to the outside of the patient, the doctor operable end section 21 of the traction vitro changing the relative position of the locking ball 22. 需要说明的是,上述锁定段25和牵引段21可以是同一根较柔软的细丝,而两个锁定球22分别固定在这根细丝上具有固定长度的两个位置上。 Incidentally, the traction segment 25 and the lock section 21 may be a filament with a relatively soft, while the two locking balls 22 are fixed to two positions having the fixed length in this filaments. 拉动牵引段21可以带动两个锁定球22在合围空间以及通道内自由移动,当把锁定件50移至通道24外后,锁定件50由紧固件23抵挡。 Pulling the segment 21 can drive two traction lock balls 22 to move freely within the space and surround channel, when the locking member 50 moves to the outer passage 24, the locking member 50 by the fastener 23 to withstand.

[0054] 由此,上述封堵器20释放后包括第一状态和第二状体。 [0054] Accordingly, the above-described release occluder 20 comprises a first state and a second state thereof. 第一状态为自由状态或松弛状态,此时锁定件50位于合围空间内,通过拉动牵引段21可自由地带动锁定件50在合围空间44以及通道24内活动。 The first state is a relaxed state or a free state, when the locking member 50 is located within the space encircled by pulling the pulling section 21 can be freely driven lock 50 and a channel 24 surround the space 44 within the activity. 当拉动牵引段21将锁定件50移出通道并由紧固件23抵挡在合围空间44或封堵器20的外部时,封堵器20处于第二状态,即所谓的锁定状态。 When the locking member 21 is pulled pulled out of the channel section 50 by a fastener 23 to withstand the external space encircled occluder 44 or 20, the occluder 20 is in a second state, i.e. a so-called locked state. 如果要释放锁定状态,只要通过操作牵引段21将锁定件50返回合围空间44即可。 To release the lock state, as long as the traction section 21 by operating the locking member 50 returns to space 44 encircled.

[0055] 图5显示的封堵器20处于自然状态,未被锁定,此时两个锁定球22在合围空间44以及通道24内可以由牵引段21带动移动。 [0055] FIG. 5 shows the occluder 20 in a natural state, it is not locked, and the two locking ball 22 can be moved by a traction drive section 21 in the channel 24 and the space 44 encircled. 参见图6,拉动牵引段21,使两个锁定球22依次从通道24穿出,并并排位于通道的近端端口处,由于两个锁定球22的直径之和大于通道24的近端直径,因此两个锁定球·22在此处由紧固件23抵挡,而无法自主返回通道24内。 Referring to Figure 6, the traction section 21 to pull the two locking balls 22 out through passageway 24 in sequence and side by side at the proximal end of the channel ports, since the two locking ball 22 and the diameter is larger than the diameter of the proximal end 24 of the channel, Thus two locking balls 23 · 22 by the fastener to resist herein, unable to return to the passage 24 customize. 由于封堵器20的总高度大于锁定段25总长度的二分之一,而此时封堵器20的远端到近端的距离通过锁丝约束,具体由锁定段25总长度的二分之一来限定,使得远端封堵单元和近端封堵单元能够更紧密地贴合在一起,从而有效地锁定封堵器。 Since the total height of the occluder 20 is greater than one-half of the locking sections 25 of the total length, at which point the distal end of the occluder 20 from the proximal end of the lock wire through constraints, particularly by a locking segment 25 of the total length of the two points one is defined such that the distal and proximal sealing means sealing unit can be bonded together more closely, thereby effectively locking the occluder.

[0056] 图7示出了紧固件23的结构示意图,应当注意的是,此处描述的紧固件23结构仅用作举例,并不是对本发明的限制,本领域的普通技术人员可以在本发明的启示下选择其它任意适合的紧固件23结构,也可以将该紧固件23结构应用到其它实施例中。 [0056] FIG. 7 shows a schematic structure of the fastener 23, it should be noted that the structure of the fastener 23 described herein way of example only, not limitation of the present invention, those of ordinary skill in the art may be select any other suitable fasteners 23 to the structure of the teachings of the invention, the fastener 23 may be applied to the structure of other embodiments.

[0057] 如图7所示,紧固件23包括外套筒60、嵌设在外套筒60内的内套筒61、以及两个套筒之间的栓头62。 [0057] As shown in FIG 7, the fastener 23 includes an outer sleeve 60, the plug is embedded between the inner sleeve 61 within the outer sleeve 60, 62 and two socket head. 由上面的描述可知,网状框架41可以是由NiTi记忆合金或者可降解高分子材料的编织丝编织构成,由于编织后的网状框架41其近端27的编织丝端部在没固定前是散开的,紧固件23中的外套筒60和内套筒61的作用在于约束和固定这些散开的编织丝,以防止编制好后的网状框架41散开,此时,编织丝固定在外套筒60和内套筒61之间的间隙内。 Apparent from the above description, the mesh frame 41 may be a NiTi shape memory alloy wires knitted or braided biodegradable polymer material composition, since the knitting yarn 41 which is a proximal end portion of the frame 27 mesh before knitting is not fixed spread, the effect of the fastener 23 in the outer sleeve 60 and inner sleeve 61 and the fixing of these constraints is that the spread woven wire mesh to prevent the frame 41 after the preparation of a good spread, this time, the knitting yarn fixing the gap between the outer sleeve 60 and inner sleeve 61.

[0058] 外套筒60和内套筒61固定编织丝的具体的操作方法为:把内套筒61套入外套筒60之内,将编织网框架41的近端27散开的编织丝均匀地插入到两个套筒之间的空隙中,通过焊接的方式将编织丝的端部熔融在一起,形成上述的栓头62,从而可以有效地防止编织网框架41散开。 [0058] Specific methods of operation the outer sleeve 60 and inner sleeve 61 is fixed to the knitting yarn: the inner sleeve into the outer sleeve 61 of the sleeve 60, the proximal end of the braided mesh 27 to the frame 41 of the knitted filament spread uniformly into a space between the two sleeve, by welding the end portion of the knitting yarn fused together, forming the above-described bolt head 62, thereby effectively preventing the spread braided mesh frame 41. 其中内套筒61的中空部分形成了通道24,是上述锁定件50以及牵引段21进出封堵器20的通道。 Wherein the hollow portion of the inner sleeve 61 forms a passage 24, the lock member 50 and is pulled out of the channel section 21 of the occluder 20. 同时内套筒61的内壁经过处理较为光滑,可以减小锁定件50通过的阻力。 While the inner wall of the sleeve 61 is treated smoother, the resistance can be reduced by the locking member 50.

[0059] 参见图8,为了提高锁定件50穿过近端紧固件通道时的顺畅性和增加运动的导向作用,可将通道24由图7中的直筒状设为梯形筒状(即圆台形),同时也可将套筒同时也设计为圆台形。 [0059] Referring to Figure 8, in order to improve the smooth action and increased movement of the guide through the proximal end of the fastener passage when the locking member 50, can be set by the straight cylindrical passage 24 in FIG. 7 trapezoidal tubular (i.e. circular trapezoidal), while the sleeve can also be designed as a truncated cone. 圆台形孔朝向网状框架内部的部分直径较大,可以增加锁定件在运动过程中与其接触的机会,当圆台形孔与锁定件发生接触之后,锁定件在牵引段拉力的作用下将沿着圆锥面向封堵器近端运动,直至离开通道。 The larger diameter portion toward the truncated cone hole of the inner mesh frame, can increase the chance of contact therewith during movement of the locking member, when the frustum-shaped aperture into contact with the locking member, the locking member under the influence of the tensioned tension along conical faces occluder proximal movement, until exit the channel.

[0060] 对于图8中的紧固件而言,圆台的锥度不能做得太大,这是因为栓头的尺寸有限,如果片面地增加圆台的锥度,即增加圆台形套筒朝向远端的直径,必然会增加栓头的外径,从而增加相应的鞘管直径,不利于手术的操作。 [0060] For the fastener in FIG. 8, the taper of the round table can not be made too large, this is because of the limited size of the bolt head, if one-sided truncated cone taper increases, i.e. truncated cone sleeve increases toward the distal end diameter, will inevitably increase the outer diameter of the bolt head, thereby increasing the diameter of the corresponding sheath, is not conducive to the operation procedure. 为了解决上述圆台型套筒存在的问题,可在封堵器的合围空间内增设弹性漏斗。 In order to solve the problem of a truncated cone sleeve type, can be added in the encircled space of the elastic funnel occluder. 参见图9,该弹性漏斗67的漏斗口朝向远端,弹性漏斗67通过漏嘴在通道24的远端与通道24连通。 Referring to Figure 9, the resilient hopper funnel 67 opening toward the distal end, the resilient hopper mouth 67 through the drain passage communicating with the distal end 24 of the channel 24. 通过将弹性漏斗67与通道24连通串接,可以进一步增加锁定件在运动过程中进入通道24机会,从而降低锁定封堵器的操作难度。 By the resilient hopper 67 communicates with the channel 24 connected in series, can further increase the locking member 24 into the passage during movement opportunities, thereby reducing the difficulty of operating the locking occluder.

[0061] 上述锁丝(牵引段21和锁定段25)由柔软而高强度的、且具有良好生物相容性的材料制成,如金属丝,弹性模量较低的高分子丝等;外套筒60和内套筒61可以由弹性较好的并具有良好生物相容性的材料制成,如弹性模量较高的高分子材料制成;锁定球22由刚度较大,不易变形的,且具有良好生物相容性的材料所制成,包括NiTi合金、不锈钢等金属以及弹性模量较高的高分子材料等。 Made of a material [0061] of the lock wire (pulling segment 21 and the locking segment 25) of a soft and high strength, and have good biocompatibility, such as a wire, lower modulus of elasticity of the polymer fiber and the like; outer sleeve 60 and inner sleeve 61 may be made of an elastic and preferably biocompatible material having good made, such as higher modulus of elasticity made of a polymer material; locking ball 22 by the larger stiffness, easily deformed and a material with good biocompatibility made, including metals and higher modulus of elasticity of the polymer material NiTi alloys, stainless steel and the like.

[0062] 其中具有良好生物相容性的的高分子材料可包括聚苯二甲酸乙二醇酯(PET:Polyethylene Terephthalate)、聚乳酸(PLA:Poly-L_lactide Acid)、聚乙醇酸(PGA:Poly-glycolide)、聚羟基脂肪酸脂(PHA:Poly_hydroxyalkanoate)、聚二氧环己酮(PD0:Poly-dioxanone),聚己内酯(PCL:Poly_caprolactone)等。 [0062] wherein the polymer material has good biocompatibility may include polyethylene terephthalate (PET: Polyethylene Terephthalate), polylactic acid (PLA: Poly-L_lactide Acid), polyglycolic acid (PGA: Poly -glycolide), poly hydroxy fatty acid ester (PHA: Poly_hydroxyalkanoate), poly dioxanone (PD0: poly-dioxanone), polycaprolactone (PCL: Poly_caprolactone) and the like. 由于同一种高分子材料经过不同的处理方式,可得到刚度不同的状态,如定向拉延后,结晶度较高的高分子材料刚性或弹性模量较大,可用来编织上述的编织网框架41和制作锁定球22 ;而无定型态的高分子材料柔性较大,可用来制作上述牵引段21和锁定段25。 Since the same polymer material through a different approach, the state of different stiffness can be obtained, such as after drawing orientation, high crystallinity rigid or elastic modulus of the polymer is large, the above can be used to weave woven mesh frame 41 and making the lock balls 22; set patterns without large flexible polymer material, used to make the take-off section 21 and the locking segments 25. 为了增加手术可操作性,采用高分子材料制成的部件包括牵引段21、锁定段25和锁定球22等。 In order to increase the operability of the operation, using components made of polymeric material comprises a traction segment 21, locking sections 25 and the lock balls 22 and the like. 同时还可以在部件外面增加可显影材料制成的涂层,便于在体外操作时通过透视等仪器下观察各自在体内的位置。 But also can increase the coating may be made of a developing material on the outside member, to facilitate observation by the respective positions of the body under fluoroscopy like in vitro instrument operation.

[0063] 锁定机构在手术中实现锁定功能可采取如下操作:首先,将封堵器20收紧进入一个直径较小的鞘管之中并输送到预定的病灶部位,并将封堵器20在病灶部位自然展开,使得封堵器20的两个封堵单元(远端封堵单元42和近端封堵单元43)尽量紧贴缺损部位的两侧;保持其中一根牵引段21的体外端不动,拽拉另一根牵引段21的体外端,在透视等仪器下可以观察到该牵引段21连接的锁定球22会往封堵器20的近端27运动。 [0063] The locking mechanism locking function implemented during surgery may take the following actions: First, the occluder 20 into the tightening into a smaller diameter sheath and delivered to a predetermined portion of the lesion, and the occluder 20 NATURAL expand the lesion site, two closure units such that occluder 20 (the distal end 42 and a proximal sealing means sealing unit 43) against both sides of the defect site as possible; wherein an outer end of holding section 21 of the traction does not move, the other end of the in vitro pull traction section 21, it can be observed that the traction section 21 is connected to the locking balls 22 will be moving toward the proximal end 27 of the occluder 20 under fluoroscopy and other equipment.

[0064] 由于单个锁定球22的直径小于通道24的直径,因此单个锁定球22在牵引段21的拽拉作用下,可以顺着牵引段21通过近端紧固件23的通道24,到达通道24的外侧;然后保持该锁定球22连接的牵引段21的体外端不动,再拽拉另一根牵引段22的体外端,使其连接的锁定球22也通过近端紧固件23的通道24,到达通道24的外侧;当这两个锁定球22都通过了通道24到达其外侧时,在透视等仪器下观察两个锁定球22的位置,并通过在体外拽拉或放松两根牵引段21调整两个锁定球22的相对位置,使其处于并排位置。 [0064] Since the diameter of the single locking ball 22 is smaller than the diameter of the channel 24, a single locking ball 22 in the pulling action of the traction section 21, the section 21 may be pulled down through the proximal end 24 of the fastener passage 23, reaches channel the outer side 24; then holds the locking ball 21 in vitro traction section 22 is connected to the fixed end, and then pull the other end of the traction vitro segment 22, so the lock balls 22 are also connected through the proximal end 23 of the fastener channel 24, to the outside of the passage 24; when both of the locking balls 22 through the passage 24 reaches its outer side, the locking balls 22 of two observation position under fluoroscopy and other equipment, and by pulling or relaxing two in vitro traction section 21 adjusts the relative position of the two locking ball 22, it is in a position side by side.

[0065] 由于在拽拉两根牵引段21的过程中,锁定段25的牵制作用改变了编织网框架41的形状,使得远端封堵单元42压缩近端封堵单元43,两者之间的距离收缩变小,并由锁定段25的长度限定。 [0065] Since the process of pulling two pulling segment 21, the locking section 25 changes the shape of the pinning effect of braided mesh frame 41, such that the distal end of the proximal occluder blocking unit 42 compression unit 43 therebetween contraction distance becomes smaller, defined by the length of the locking section 25. 然而编织网框架41自身是采用具有良好弹性的材料制成,具有形状记忆特性,因此编织网框架41有恢复至其原有形状的倾向,这样使得锁定段25对其连接的两个锁定球22产生一个拉力作用,在锁定段25的拉力以及近端处的紧固件23的阻挡作用力的平衡作用下,最终可使得这两个锁定球22并排位于通道24的外侧,如图6所示。 However, braided mesh frame 41 itself is made of a material having good elasticity, shape memory characteristics, so braided mesh frame 41 tends to return to its original shape, so that its arresting portion 25 connected to two locking balls 22 generating a tensile force, the locking force equilibration period and a fastener 25 at the proximal end 23 of the lower barrier force, eventually the locking ball 22 such that the two side by side positioned outside the channel 24, as shown in FIG. 6 .

[0066] 为了更好地完成上述的手术操作,封堵器20的各个部件具有一个优选的尺寸关系。 [0066] In order to accomplish the above surgical procedures, the various components of the occluder 20 has a preferred dimensional relationship. 封堵器20 —般采用介入手术的方式对缺损部位进行封堵,因此植入器械必须可以收紧进入一个直径较小的鞘管之中。 Occluder 20 - as by way of surgical intervention for closure of the defect site, and therefore must be tightened into the implantation instrument into a small diameter sheath. 在本实施例中,鞘管的大小可以根据封堵器20的规格来选择,一般内径可以为4F~14F (F为常用的长度单位,lmm=3F)。 In the present embodiment, the size of the sheath may be selected according to the specifications of the occluder 20, the inner diameter may be generally 4F ~ 14F (F is a common unit of length, lmm = 3F). 而为了使封堵器20能在鞘管内顺利输送,单个锁定球22的直径可以为0.5~1.8_,两个锁定球22的直径之和比鞘管的直径要小0.3~1_,因此封堵器20连同锁定机构可以被收紧进入鞘管,进而沿着输送系统到达指定的缺损部位。 In order occluder 20 can be smoothly conveyed in the sheath, the single locking ball 22 may have a diameter of from 0.5 to 1.8_, two locking ball diameter and the ratio of the diameter of the sheath 22 is less 0.3 ~ 1_, thus blocking 20 together with the locking mechanism can be tightened into the sheath, and thus reaches the specified defect along the conveyor system.

[0067] 为了使得单个锁定球22可以顺利的通过通道24,单个锁定球22的直径要比位于紧固件23的通道24的近端直径小0.1~0.5mm。 [0067] In order that a single locking ball 22 can smoothly through the passage 24, a single locking ball 22 is located in diameter than the small-diameter passage 23 proximal fastener 24 of 0.1 ~ 0.5mm. 而实施锁定功能之后的封堵器20的高度由锁定段25的长度来限定,因此为了确保远端封堵单元42和近端封堵单元43之间的距离与缺损位置的厚度相适应,锁定段25的长度可以为7~25mm。 While occluder 25 lengths after the height of the embodiment of the locking function of the lock 20 is defined, so in order to ensure the thickness of the distal occluder element 42 and the distance between the position of the defect occluder means 43 to adapt the proximal end, the locking length 25 may be 7 ~ 25mm. 该远端封堵单元42和近端封堵单元42的总高度大于该锁定段25总长度的二分之一。 The distal end 42 and a proximal sealing means sealing unit 42 is greater than the total height of the lock half of the total length of the section 25.

[0068] 当锁定机构完成对封堵器20的锁定之后,需要将牵引段21沿输送鞘管撤出体外,撤出的方式有多种,一般可以采用在输送系统中连接钢缆的端部增加的剪刀、钳子等剪断工具将牵引段21在锁定件50的连接点处剪断,并将剪断后的两根牵引段21撤出体外。 [0068] When locking the locking mechanism after the completion of the occluder 20, 21 need to be tensioned in the conveying vitro sheath withdrawn, the withdrawal of a variety of ways, generally the ends of the connecting cable may be used in the delivery system increased scissors, pliers and other tools to cut the traction section 21 cut at the connection point of the locking member 50, 21 and the withdrawal period after the in vitro two pulling cut. 这种处理方式存在一个弊端,就是在通道24外侧残留的一小段牵引段21容易造成对心脏内组织的损伤。 A disadvantage of this approach exist, a short passage 24 that is outside residual traction segment 21 is likely to cause damage to the heart tissue.

[0069] 图10中的锁定件的结构解决了上述问题,应当注意的是,此处的锁定件结构仅用作举例,并不是对本发明的限制,本领域的普通技术人员基于本发明的启示也可以选择其它适合的锁定件结构,例如锁定段25的端部可以通过焊接,胶接等方式与锁定球22相连;且该锁定件结构也适用于其它实施例。 [0069] The configuration in FIG. 10 of the locking member to solve the above problems, it should be noted that the structure of the locking member here way of example only, not limitation of the invention, the revelation of ordinary skill in the art based on the present invention. can also select other suitable locking member structure, such as a locking end section 25 by welding, gluing, etc. is connected with the lock balls 22; and the locking member configuration is also applicable to other embodiments.

[0070] 如图10所示,锁定球22 (也可以是其它任意结构的锁定件)上设有通孔39,牵引段21穿过该通孔39与锁定件连接,并且牵引段21的两端均穿过通道24沿着输送系统一直延伸到体外用于操控。 [0070] 10, the locking ball 22 (may be any other configuration of the locking member) 39 provided with a through hole, through which the traction portion 21 connecting the through hole with the locking member 39, and the traction of the two sections 21 through the end of each passage 24 extends along the transport system to the in vitro for manipulation. 在这种情况下,体外共有四个牵引段21的体外端,同一根牵引段21上的两个体外端用来控制一个锁定球22。 In this case, a total of four in vitro pulling the outer end portion 21, two in vitro with a traction on an end section 21 for controlling a locking ball 22. 当需要锁定封堵器20时,可以同时拽拉同一根牵引段21的两个体外端,带动该牵引段21上的锁定球22运动。 When it is desired to lock the occluder 20, the two may simultaneously pull the outer end with a traction section 21 to drive the locking ball 22 moves on the traction section 21. 随着两个锁定球22都被拉至近端紧固件23上通道24的外侧,并通过锁定段25约束封堵器20的远端封堵单元42和近端封堵单元43达到理想的形态时,松开牵引段21的任意一个体外端,然后拽拉该牵引段21的另一个体外端,牵引段21上的松开的那个体外端会通过小孔39,最终脱离锁定球22完全撤出体外。 With two locking balls 22 are pulled to the proximal end of the fastener 23 on the outside of the channels 24, 25 and constrained by the locking section occluder distal end 20 and a proximal end 42 of the closure means 43 closure means to achieve the desired when the form, the outer end of a traction release any segment 21, and then pulling the other outer end section 21 of the tow, pulling on the outer end section 21 will be loosened through the apertures 39, the final locking ball 22 is completely disengaged withdraw from the body. 利用同样的方法,可以使得两根牵引段21都分别脱离相应的锁定球22。 Using the same method, so that the two sections 21 are respectively pulled out of the respective locking balls 22.

[0071] 从以上可以看出,采用图10中的锁定件结构,可以完全去除锁定件上外露的锁丝,避免残留外露的牵引段21对心脏内组织造成损伤的问题,从而防止外露的锁丝对心脏组织或血管组织的损伤。 [0071] As can be seen from the above, the locking member employed in the structure of FIG. 10, the lock may be completely removed wire exposed on the lock member, to avoid residual tissue sections exposed traction problems caused by damage to the heart 21, thereby preventing the exposed lock silk tissue damage to the heart or vascular tissue.

[0072] 为了减少约束后的锁定件50在封堵器20的通道24外侧的过分突出,以及进一步加强锁定件50在通道24外的约束,以增加锁定机构的稳定性,如图11所示,可以在紧固件23的近端处设置与通道24相通的凹槽28,锁定件拉出通道24后收容于该凹槽28中。 [0072] In order to reduce the locking member 50 in the constrained outer passage 24 of the occluder 20 protrude excessively, and further enhance the locking member 50 constrained passage 24 outside, in order to increase the stability of the locking mechanism shown in Figure 11 , fastener 23 may be provided at the proximal end of the passage 24 communicating with the recess 28, the locking member 24 is pulled out after the channel received in the recess 28. 应当注意的是,此处的紧固件结构仅用作举例,并不是对本发明的限制,封堵器中可以选用其它任意适合的紧固件结构;且该紧固件也可用于其它实施例中的封堵器。 It should be noted that the structure of the fastener here way of example only, not limitation of the invention, the occluder may choose any other suitable fastener structure; and the fastener may also be used in other embodiments the occluder.

[0073] 该凹槽28的宽度要比两个锁定球22的直径之和略大,在实际产品设计中凹槽28的宽度要比两个锁定球22的直径之和大0.1~0.5mm。 Width [0073] The recess 28 is slightly larger than the sum of the two diameters of the lock balls 22, in the actual product design than two diameters of the locking ball 22 and the large 0.1 ~ 0.5mm width of the groove 28. 当这两个锁定球22都被拽拉穿过通道24后可正好位于凹槽28内,凹槽28可以精确的定位两个锁定球22的位置,有效地防止两个锁定球22在横向上发生偏移而导致其中一个锁定球22穿过通道24自主回到编织网框架41的内部,从而丧失锁定的功能。 When the two lock balls 22 are pulled through the channels 24 may be located just inside the recess 28, the recess 28 can be precisely positioned locking balls 22 in two positions, in the lateral direction effectively prevents two locking balls 22 resulting in one of the locking ball 22 back into the interior through the passage 24 customize braided mesh frame 41, so that the locking function is offset loss. 可以理解的是,这种开设凹槽的设计同样可以应用于后面的具体实施例中。 It will be appreciated that this open groove behind the design is equally applicable to the specific embodiments.

[0074] 从以上可以看出,锁定机构仅包括锁丝21,25 ;以及锁定件50,结构简单。 [0074] As can be seen from the above, only the locking mechanism comprises a locking wire 21, 25; and a locking member 50, a simple structure. 操作中,拉动锁丝21以使封堵器20的远端封堵单元42压缩近端封堵单元43,并通过紧固件23抵挡锁定件50来保持这种压缩状态,以实现锁定封堵器,操作简易。 In operation, pulling the lock wire 21 to cause the distal occluder 20 of the occluder proximal end of the compression unit 42 blocking unit 43, and to maintain this compressed state by fasteners 50 to resist the locking member 23, in order to achieve locking closure , a simple operation. 封堵器20锁定后,第二状态下的封堵器20的远端到近端的距离小于该封堵器20的总高度,因此锁定状态下的近端封堵单43和远端封堵单元42能固定贴合,从而改善封堵器在体内的成型形态,防止其成型不良导致的各类手术并发症,比如血栓,内皮不能完全爬覆等。 After the occluder 20 is locked, the distal end of the occluder 20 in the second state to a distance less than the total height of the proximal end of the occluder 20, thus locking the proximal end of the blocking state of the single block 43 and a distal end fixing unit 42 can be bonded, thereby improving the occluder body molded form, to prevent the molding failure caused by various types of surgical complications, such as thrombosis, endothelial crawl not completely cover the like.

[0075] 由于仅通过拉动锁丝21即可实现锁定状态,因此可以在体外操作锁丝21来完成锁定过程以及锁丝21撤出的操作,使得手术操作相对简单和方便,而且锁定稳定性好,不易失效,提高了封堵器在体内的封堵稳定性,防止其从缺损部位脱落,减少封堵器制作过程中对编织丝性能的要求。 [0075] Because only 21 to realize the locked state by pulling the wire lock, the lock can be manipulated in vitro lock wire 21 to complete the operation and during the withdrawal of the lock wire 21, so that the surgical operation is relatively simple and easy, good stability and locking , easy to failure to improve the stability of the occluder in the body of the occluder to prevent it from coming off the defect site, reducing the occluder production process of claim knitting yarn properties.

[0076] 采用柔软的、弹性较好的丝线作为锁丝来约束封堵器两个封堵单元之间的距离,因锁丝本身具有一定程度的弹性变形能力,可以进一步提高封堵器的变形协调能力。 [0076] The flexible, preferably elastic threads as a lock wire to restrict the distance between the two closure units occluder, because the lock wire itself has a certain degree of elastic deformability, can be further improved modification occluder Coordination.

[0077] 锁丝穿过网格框架41a,无需固定连接于封堵器的远端结构,因此适用于无远端结构的封堵器。 [0077] Lock part through the grid frame 41a, without a fixed connection to the distal end of the occluder structure, it is applied to the distal end of the occluder without structure. [0078] 实施例一中封堵器20的两个锁定球22之间锁定段25的长度固定不变,可能不易适应各种不同厚度的缺损。 [0078] In one embodiment the occluder two locking balls 20 locking section 25 of fixed length 22, may be difficult to adapt to various thicknesses of the defect. 为了使同一封堵器可以适应不同厚度的缺损,需要一种封堵器,可通过调节锁定机构以使远端封堵单元42和近端封堵单元43之间保持不同的距离,从而能够适应不同个体或不同组织部位之间所产生的差异。 In order that the same can be adapted to the defect occluder of different thicknesses, a need for an occluder, by adjusting the locking mechanism to block the distal end 43 to maintain a distance between the different cells 42 and a proximal sealing means, it is possible to accommodate difference generated between the different tissues or different individuals.

[0079] 如图12所示,在实施例一的基础上,实施例二中的封堵器30的锁定件包括锁定球22a,22b、以及连接在牵引段上的至少一个调节球,例如图13中的调节球22c,22d。 [0079], in an embodiment based on the embodiment, the locking occluder 12 according to the second embodiment of the member 30 includes a locking ball 22a, 22b, and connected to the leader section of the at least one adjustment of the ball, for example, FIG. adjusting the ball 13 22c, 22d. 每个调节球的直径均小于通道的最小直径,且两个调节球的直径之和或者任意一个锁定球与任意一个调节球的直径之和均大于通道24的近端直径。 Adjusting the diameter of each ball is less than the smallest diameter channel, and adjusting the diameter of the two balls and a locking ball or any adjustment with any of a ball diameter and greater than the diameter of the proximal end 24 of the passage. 牵引段21分为两根,每一根牵引段的一端与一个锁定球相连,每一根牵引段的另一端穿出通道24 ;封堵器30的总高度大于一根牵引段上的锁定球和调节球中的一个与另一根牵引段上的锁定球和调节球中的一个之间的锁丝长度的二分之一。 Traction segment 21 is divided into two, one end of each of the traction section is connected with a locking ball, pulling the other end of each of the piercing channel section 24; total height of the occluder 30 is greater than a traction on the locking ball segment and adjusting the locking balls and the other on a traction ball segment and one-half lock regulating filament length between one ball.

[0080] 可以根据实际需要在锁定件50的锁定球和调节球中选择两个球体(将锁定球和调节球统称为球体)以形成合适的组合来锁定封堵器,选择球体的不同,造成限定封堵器的远端到近端的距离的锁丝长度不同,从而可以适应不同厚度的缺损。 [0080] In the lock according to actual needs and the adjustment member locking ball select two balls of the ball 50 (ball lock balls and collectively adjusted sphere) to form a suitable combination lock occluder, select a different sphere, resulting in defining the distal end of the lock occluder filament length different from the proximal end, which can accommodate different thicknesses of the defect. 以如图12为例,其中一个锁定球22a固定在一根牵引段的一端;另外一个个锁定球22b和两个调节球22c和22d依次固定在另一根牵引段上。 In Example 12, a ball 22a which is fixed to one end of a traction lock segment; additional one locking ball 22b, and two balls 22c and 22d are sequentially adjusted on the other fixed to the traction section. 这四个球体之间锁丝的长度设置可以优选为:锁定球22a与22b之间锁丝的长度为7~25mm,用以大致适应远端封堵单元42和近端封堵单元43之间的距离与缺损位置的厚度。 The length of the wire lock may be provided between the four spheres preferably: the length of the locking balls 22a and 22b of the lock wire between 7 ~ 25mm, a distal end adapted for substantially blocking unit 42 and the proximal occluder element 43 the thickness of the distance from the defect sites. 锁定球22b、调节球22c和22d可以依次等距排布,例如间距可以为I~2mm,用于调整封堵器以达到最佳的形态。 Locking ball 22b, 22c and 22d may be adjusted balls arranged sequentially equally, for example, the pitch may be I ~ 2mm, for adjusting the occluder to achieve the best morphology.

[0081] 为了操作的可靠性,锁定段25上每个球体的直径尺寸设定为基本相同。 [0081] For reliable operation, the locking segment 25 on the diameter of each sphere is set to be substantially the same. 在手术过程中医生可以根据实际预先测量得到的缺损厚度尺寸来选择适当的两个球体对封堵器30的两个封堵单元进行约束,以得到封堵器30最为理想的成型形态,如图13所示,选用图12中的锁定球22a和调节球22c对封堵器进行锁定操作。 During the procedure the physician may be selected according to the thickness dimension of the defect actually measured in advance to obtain an appropriate two spheres of two units occluder occluder 30 is constrained to obtain the most desirable molding 30 forms occluder as , the selection and adjustment locking ball 22a in the ball of FIG. 12 22c 13 occluders perform the locking operation.

[0082] 在手术过程中通过显影观察,选定的两个球体可以顺利地依次通过通道24到达该通道24的近端外侧,此时作为锁定件50的第一状态,即指的是锁定件50可以自由地通过通道24。 [0082] In the procedure developed by observation, two spheres may be selected sequentially smoothly to the proximal end of the outer passage 24 through the passage 24, this time as the first state of the locking member 50, referring to the locking member 50 can freely through the passage 24. 当选定的两个球体先后被牵引段21拉至封堵器30的通道24的外侧,并被调整位置并排位于通道24的外侧后形成锁定件50的第二状态,即锁定件50其横向尺寸(两个球体圆心连线方向上的尺寸,即等于两个球体直径之和)大于通道24的近端直径,使得约束后的锁定件50很难通过通道24再自主返回到编织网框架41的内部,从而达到改善封堵器30的成型性能的目的。 When the selected two spherical segment 21 has been pulled to pull the occluder 30 of the outer channel 24, and is positioned in parallel to adjust the position of the locking member 50 is formed of a second state after the outer passage 24, i.e., locking member 50 transversely after the locking member (dimension in the direction connecting the centers of the two spheres, which is equal to the sum of two spherical diameter) larger than the diameter of the proximal end 24 of the passage, so that constraints difficult to customize 50 returns to the frame 41 through the passage braid 24 interior, so as to achieve the purpose of improving the moldability of the occluder 30.

[0083] 本实施例中的锁定操作过程与实施例一相同,在显影观察条件下选择的两个球体定位完成后,可以采用在连接钢缆端部增加的剪刀、钳子等剪断工具,将外露的锁丝在靠近并排的两个球体的位置进行剪断,剪断后的部分可以被牵引段21拉至体外。 [0083] a locking same procedure as in Example embodiments of the present embodiment, after selecting two spheres positioned in the developing complete viewing conditions, may be employed to increase the connecting cable ends scissors, pliers and other tools to cut, the exposed the lock yarn was cut at a position near the two spheres side by side, the cut portion of the rear section 21 can be pulled to pull out of the body.

[0084] 图14示出了依据本发明实施例三的封堵器40的示意图,其与上述实施例一和二的区别在于锁定机构。 [0084] FIG. 14 shows a schematic view of an occluder 40 according to a third embodiment according to the present invention, which differs from the above embodiment in that a locking mechanism and II. 如图14所示,锁定件为一个长条形锁定件31,锁定段25的一端连接锁定件31的长边侧,优选为长边侧中部,另一端穿过网格框架41a后返回到编织网框架41的内部,即合围空间内,并通过固定点34固定在紧固件23的远端。 14, the locking member is a locking elongated member 31, one end of the locking section 25 is connected to the long side of the locking member 31, preferably the central long side, through the other end of the grid frame 41a is returned to the knitting intranet frame 41, i.e. the space encircled and secured by a fixing point 34 in the distal end 23 of the fastener. 锁定段25穿出和穿进的网孔优选位于封堵器20的远端26处位置对称的两个网孔,锁定段25从其中一个网孔穿出,从对称的另一个网孔穿入,穿入编织网框架41的内部的锁定段25末端连接长条形锁定件31,封堵器40的总高度大于锁定段25的总长度的二分之一。 The locking section 25 and piercing through the mesh into the distal end of the occluder 20 is preferably located at the two symmetrical positions 26 mesh, wherein the locking section 25 out through a mesh, another mesh from penetration symmetrical penetrates into the woven mesh 41 inside the frame locking section 25 connected to the end of the elongated locking member 31, the total height of the occluder 40 is greater than one-half the total length of the locking sections 25. 牵引段21的一端连接在锁定件31的短边侧,另一端穿出通道,并沿着输送系统一直延伸到患者体外,供医生操作。 One end section 21 is connected to the traction on the short side of the locking member 31, the other end of the piercing channel, and extends along the conveyor system outside the patient, the doctor for the operation. 锁定件与锁丝之间可以通过打结、焊接等方式固定。 Between the locking member and the lock wire through knotting, welding or the like is fixed. 锁定段25也可以是编织网框架41在编织时,在远端封堵单元42的远端26位置处预留的额外编织丝。 The locking section 25 may be a braided mesh frame 41 when knitting, braiding the wire in the distal end blocking additional remote unit 42 at a position 26 reserved. [0085] 长条形锁定件31的长边侧尺寸大于短边侧尺寸,当长条形锁定件31的长边侧与通道24轴向平行时,由于通道24的直径设置比长条形锁定件31的短边侧尺寸大,因此长条形锁定件31可以顺利地通过通道24,此时作为长条形锁定件31的第一状态。 [0085] The elongate locking member 31 of the long side dimension is larger than the size of the short side, when the elongated locking member 31 with the long side parallel to the axial passage 24, since the diameter of the passage 24 is longer than the locking strip size of the short side member 31 is large, so the elongated locking member 31 can be smoothly through the passage 24, this time as a first elongated member 31 of the locking state. 而当长条形锁定件31的长度方向与通道24轴向垂直时,由于通道24的最大直径设置为比长条形锁定件31的长边侧尺寸小,长条形锁定件31被卡住无法通过通道24再回到编织网框架41的内部,此时作为长条形锁定件31的第二状态,实现封堵器40的锁定。 When the elongated longitudinal direction of the locking member 24 perpendicular to the axial passage 31, since the maximum diameter of the passage 24 of the long side member 31 is smaller in size, than the elongated locking member 31 is elongated locking caught We can not go back inside braided mesh frame 41 through the passage 24, the second state at this time as the elongated locking member 31, 40 to achieve locking closure.

[0086] 为了增加封堵器植入缺损部位后的封堵效果,封堵器中还可以缝合有阻流膜,阻流膜的数量可以不同,且阻流膜上设有用于通过锁定件的开孔。 [0086] In order to increase the effect of blocking the implant the defect occluder, the occluder may also be sewn in the flow blocking film, the number of flow blocking film may be different, and the baffle is provided with a film by a locking member opening. 应当注意的是,此处的阻流膜设置仅用作举例,并不是对本发明的限制。 It should be noted that the flow blocking film is provided herein only as example not limitative of the present invention. 另外,其它实施例的封堵器中同样可以设置阻流膜,并可以根据需要选择阻流膜设置的位置和数量。 Additionally, other embodiments of the occluder may be provided in the same flow blocking film, and may be the position and number of flow blocking film provided according to need to choose.

[0087] 为了更好地达到锁定的功能,长条形锁定件31和通道24的尺寸具有一个最优的范围。 [0087] In order to achieve the locking function, the locking member 31 elongated channel 24 having dimensions and an optimal range. 例如,通道24的直径取值范围为0.6~2.3mm,比长条形锁定件31横截面方向的最大直径(即上述的宽度尺寸)大0.1~0.5mm,从而使得长条形锁定件31可以沿着长度方向方便穿过通道24。 For example, the diameter of the channel 24 in the range of 0.6 ~ 2.3mm, the locking member 31 is longer than the maximum diameter of the strip (i.e., the above-mentioned width dimension) of 0.1 ~ 0.5mm in the cross-sectional direction, so that the elongated locking member 31 can be to facilitate passage through the longitudinal direction 24. 为了实现锁定的功能,长条形锁定件31的长边侧尺寸比通道24的直径大0.5~3_。 In order to achieve the locking function, the locking member 31 is elongated long-side size larger than the diameter of the passage 24 0.5 ~ 3_. 当存在阻流膜时,为了减少阻流膜开孔对封堵器阻流效果的影响,阻流膜上的开孔直径也有一定的要求。 When there is flow blocking film, to reduce the effect of the flow blocking diaphragm opening occluder choking effect of the baffle film opening diameter have certain requirements. 中央开孔的最大孔径为I~4mm,比长条形锁定件31横截面方向的最大直径大0.5~2.2mm。 The maximum pore diameter of central opening I ~ 4mm, the elongated locking member 31 than the cross-sectional direction of the maximum diameter of 0.5 ~ 2.2mm.

[0088] 图15示出了依据本发明实施例四的封堵器70的示意图,其与上述实施例三中的封堵器40的区别在于锁定段25的连接方式。 [0088] FIG. 15 shows a schematic diagram 70 according to a fourth embodiment of the present invention according to the occluder, which differs from the embodiment described above three occluder 40 in that the locking section 25 of the connection. 如图15所示,锁定件为一个长条形锁定件31a,锁定段25的两端固定在锁定件31a的长边侧,优选固定在长边侧中部同一横截面上位置对称的两个点。 15, the elongated locking member is a locking member 31a, the locking section 25 is fixed to both ends of the long side 31a of the locking member is preferably fixed to the long side of the central position of the same cross-section symmetrical two points . 锁定段25可以从网格框架41a的任意一个网孔穿出到达编织网框架41的外侧,同时又从网格框架41a的另一个不同的网孔穿进返回到网状框架41形成的合围空间内部。 Piercing the locking segment 25 may reach the outer braided mesh frame 41 from any one cell of the grid frame 41a, while the other grid frame and from a different cell 41a penetrate into the frame 41 to return to the mesh spaces formed encirclement internal. 为了保持受力的均匀性,上述穿进穿出的两个网孔的位置优选位于封堵器20的远端26处位置对称的两个网孔。 In order to maintain the uniformity of the force of the two cells through piercing position into the distal end of the occluder 20 is preferably located at the two symmetrical positions 26 mesh.

[0089] 图16示出了依据本发明实施例五的封堵器80的示意图,其与上述实施例三中的封堵器40的区别在于锁定段25的连接方式。 [0089] FIG. 16 shows a schematic view of the occluder 80 according to a fifth embodiment according to the present invention, which differs from the above three embodiments in that the occluder 40 is connected to the locking section 25 of the embodiment. 如图16所示,锁定段25是自闭合的。 16, the locking section 25 is self-closing. 锁定件31b的长边侧设有通孔71,通孔71优选位于长边侧中部。 The long side 31b of the locking member 71 is provided with a through hole, the through hole 71 preferably located in the middle of the long sides. 锁定段25从网格框架41a的任意一个网孔穿出到达编织网框架41的外侧,接着从网格框架41a的另一个不同的网孔穿进返回到网状框架41的内部,同时再穿过长边侧小孔71,形成一个闭合结构。 A locking section 25 from any cell grid frame 41a reaches the outside of the piercing braided mesh frame 41, and then from the other grid frame 41a is different from the mesh into the interior through the return to the mesh frame 41, while wear long side of aperture 71, to form a closed structure.

[0090] 图17示出的封堵器中缝合有三片阻流膜(66a,66b和66c)。 [0090] FIG. 17 shows the occluder in the baffle is sewn three films (66a, 66b, and 66c). 具体而言,可在封堵器40的近端封堵单元内43、远端封堵单元42内以及远端封堵单元42与近端封堵单元43的连接部45 (即通常所说的腰部)内均设有阻流膜。 Specifically, the proximal occluder 40 of the occluder means 43, the distal end 42 and a distal closure means 42 closure means sealing the proximal end portion 45 connected to unit 43 (i.e., commonly referred to as the waist) are provided with flow blocking film. 优选地,近端封堵单元内43和连接部45内的阻流膜66b和66c上设有用于通过锁定件的孔。 Preferably, the flow blocking film provided for 66b and 66c and the connecting portion 45 within the proximal end 43 through the hole blocking unit lock member.

[0091] 手术过程中,封堵器具有两个极限的状态,一是封堵器完全被收进鞘管;二是锁定件穿过栓头中心孔到达封堵器的外侧,使得封堵器展开为其预定型的形状。 [0091] During surgery, the occluder having two limit state, one occluder is fully incorporated into the sheath; two locking pin member passing through the central bore to the outside of the first occluder, the occluder such that its predetermined expanded shape type. 由于位于远端封堵单元42的阻流膜66a与远端封堵单元42的直径相同或者更大,因此当封堵器被完全收进鞘管时,阻流膜66a可以完全紧贴远端封堵单元42的编织结构而发生折叠。 Since the flow blocking closure membrane at the distal end 66a and the diameter of the distal occluder element 42 of the same unit 42 or greater, so that when the closure is fully retracted into the sheath flow blocking film 66a may completely close the distal end knitted structure folded closure unit 42 occurs. 然而在收进鞘管过程中66a和腰部的阻流膜66b之间的距离会变大,超过锁丝的长度。 However, the distance between the baffle film 66b 66a becomes larger in the waist and incorporated into the process of the sheath, more than the length of the locking wire. 因此当封堵器被完全收进鞘管时,锁定件31b会位于阻流膜66a和66b之间。 Therefore, when the occluder is fully retracted into the sheath, the locking member 31b will be positioned between the film 66a and the baffle 66b.

[0092] 显然当锁定件31b要完成锁定功能时,它需要穿过两层阻流膜66b和66c。 [0092] Obviously, when the locking member 31b to complete the lock function, it needs to pass through two flow blocking films 66b and 66c. 因此为了使得锁定件50可以顺利地通过阻流膜66b和66c,这两层阻流膜必须经过处理,需要在阻流膜66b和66c的中央增加一个开孔,可以为一个线状开孔,十字开孔,圆形开孔或者其它形状的开孔。 Therefore, in order that the locking member 50 can smoothly pass through the film baffle 66b and 66c, these two baffle films must be treated in the required central flow blocking film 66b and an opening 66c is increased, and may be a linear opening, cross openings, circular openings or openings of other shapes. 由于位于近端封堵单元43中心处的紧固件23 (即栓头)附近编织丝的密度较大,可以起到一定的阻流作用,而两个封堵单元和腰部的边缘位置处,由于编织丝的密度较为疏松,对血液流动的阻碍作用较小。 Since the proximal end of the occluder is located in the center of the fastener 23 unit 43 (i.e., bolt head) near a knitting yarn of a larger density, the flow resistance can play a role, and the positions of the two edges and waist closure units, Since the knitting yarn density looser, less impediment to blood flow. 因此阻流膜中央位置开一个小孔对阻流效果影响较小。 Thus flow blocking film for a small opening in a central location choking effect less affected. [0093] 如图18所示,锁定件31b上设有通过锁定段25的通孔71,并在近端尾部设有通过牵引段21的通孔39,通孔39和71优选为两个平行的通孔。 [0093] As shown in FIG 18, the locking member 31b is provided on 71, and a tail portion at the proximal end through the locking section 25 of the through hole by pulling segment 21 of the through hole 39, the through holes 39 and 71 is preferably two parallel the through-hole. 一旦锁定件31b移出封堵器,抽出牵引段21到体外以确保牵引段21在体内无残留。 Once the locking member 31b out of the occluder, pulled out from the body 21 in the body section 21 to ensure that no residual tensioned.

[0094] 为了使长条形锁定件31b可以顺利进入通道24内,还可以在长条形锁定件31b连接牵引段21的端部位置设置成圆弧形过渡区域45。 [0094] In order to lock the elongated member 31b can smoothly enter the channel 24 may also be locked in the elongated member 31b connected to the trailing end portion 21 is set to position segment arc-shaped transition region 45. 为了保证锁定机构功能的稳定性,需合理设置锁定段25与长条形锁定件31b连接点,锁定段25与长条形锁定件31b的固定连接点离连接有牵引段21的端部顶点的距离定义为LI,长条形锁定件31b的长度尺寸定义为L2,在本实施例中L1/L2的比值优选为0.25~0.75。 In order to ensure the stability of the function of the locking mechanism, the locking section 25 is provided for an reasonable elongated locking member 31b and the connection point, the connection point 25 and the fixed locking elongated member 31b of the locking section is connected with the traction section end portion 21 from the apex of is defined as the distance LI, elongated length dimension of the locking member 31b is defined as L2, the ratio embodiment L1 / L2 is preferably 0.25 to 0.75 in the present embodiment. 如图19所示,为了使得长条形锁定件31b能够更加顺利地进入通道24,也可将长条形锁定件31b的近端设置成锥形引导区域32,该锥形引导区域32的顶点处位置连接牵引段21,这里的锥形引导区域32所起的作用与上述的圆弧形过渡区域45类似。 , In order that the elongate locking member 31b can be more smoothly into the channel 24, also the elongated locking member may be arranged to the proximal end 31b of the guide tapered region 32, the tapered guide region 32 of the apex 19 in FIG. at the position of the connecting section 21 of traction, where the tapered guide role similar to the above region 32 transition region 45 of arc-shaped.

[0095] 参见图19,长条形锁定件31b的远端或者可设有楔形端面65,当长条形锁定件31b被拽拉到通道24的外侧时,长条形锁定件31b可以沿着该楔形端面65滑动,更加自由地发生旋转,从第一状态转变为第二状态,而不会发生长条形锁定件31b边缘卡在通道24处无法旋转的现象。 [0095] Referring to Figure 19, the distal end 31b elongated locking member or may be provided with wedge-65, when the elongated locking member 31b is drawn to the outside passage 24 is pulled, the locking member 31b can be elongated along the wedge-slide 65, the rotation occurs more freely, transition from a first state to a second state, does not occur while the elongated locking member 31b in the phenomenon of edge card 24 can not be rotated at the channel.

[0096] 参见图14~19,为了加强各封堵器的两个封堵单元的贴合效果,改善成型形态,利用锁定机构来锁定封堵器(40,70,80,90)的操作如下:通过体外操作拽拉该牵引段21的体外端,使得长条形锁定件(31,31a, 31b)可以沿着牵引段21向封堵器的近端27运动,优选地,在上述锥形引导区域32或圆弧形过渡区域45的导引作用下,长条形锁定件能够顺利的进入近端紧固件23的通道24内,由于通道24的约束,长条形锁定件31可以顺着孔腔通过通道24。 [0096] Referring to FIGS. 14 to 19, the effect to strengthen the bonding of the two occluder block units, to improve the molding form, to lock the occluder (40,70,80,90) by the lock mechanism operates as follows : in vitro pull the pulling operation of the outer end section 21, so that the elongated locking member (31,31a, 31b) can be pulled in the proximal segment 21 to the motion 27 of the occluder, preferably, in the above-described tapered active area 32 under the guidance of the guide or arc-shaped transition region 45, the elongated locking member can smoothly into the proximal end of the fastener 24 within the channel 23, since the constraints of channel 24, the locking member 31 can be elongated cis the bore 24 through the passage.

[0097] 而当长条形锁定件完全通过通道24时,该长条形锁定件失去通道24的限制,同时在锁定段25和牵引段21的共同作用下,长条形锁定件所受到的总的拉力的方向与其长度方向不一致,导致长条形锁定件与锁定段25之间会形成一定的角度,当逐渐松开牵引段21时长条形锁定件发生旋转,旋转后的长条形锁定件其长度方向不再与近端紧固件23的通道24平行,并且长条形锁定件其长度方向的尺寸要大于通道24的直径,导致长条形锁定件被卡在通道24外侧,很难再通过通道24再回到编织网框架41的内部。 [0097] When the locking member is completely elongated through passage 24, the elongated locking member 24 to limit the loss of the channel, while the locking section 25 and section 21 of the traction interaction, the elongated locking member is subjected total inconsistent pull direction to the longitudinal direction, resulting in elongated locking member and the locking segments form an angle between 25, when gradually release the tensioned elongated locking the rotary member 21 occurs, the rotation of the elongated locking member longitudinal direction is no longer parallel to the proximal end 23 of the fastener passage 24, and an elongated locking member in the longitudinal direction dimension greater than the diameter of the passage 24, resulting in elongated locking member 24 is caught at the outer channel, is braided mesh can no longer return to the internal frame 41 through the passage 24. 由于锁定段25的两端距离是固定的,这样封堵器的远端封堵单元42和近端封堵单元43之间的距离可被压缩至预定的大小并保持恒定。 Since the distance between ends of the locking segment 25 is fixed, so that the distal end of the occluder 42 and occluder proximal occluder means a distance between the unit 43 may be compressed to a predetermined size and kept constant.

[0098] 当长条形锁定件定位好后,对于牵引段21的处理,可以采用与实施例一相同的方式。 [0098] When the elongate locking member positioned, the processing section 21 for traction can be employed the same manner as in Example a. 即可以在连接钢缆端部增加剪刀、钳子等剪断工具,将外露的牵引段21进行剪断。 That can increase the scissors, pliers and other tools to cut the connecting cable end portion, exposed to the traction section 21 cut. 此外,设计了如图18和19所示的锁定件结构,可以完全避免剪断后残留的牵引段21对组织的损伤以及产生血栓等问题。 Furthermore, the design of the structure 18 and the locking member 19 shown, can be completely avoided injury remaining cut segments 21 of the traction of tissue and generating thrombosis problem. 长条形锁定件31的近端尾部设有通孔39,牵引段21是一段开环的、柔软的金属丝或高分子丝,该牵引段21的穿过通孔39并且它的两端沿着输送系统一直延伸到体外,因此在牵引段21体外共有两个体外端。 The proximal end of elongated tail portion 31 of the locking member is provided with a through hole 39, 21 is tensioned section of the ring-opening, flexible wire or a polymer wire, through the through bore section 21 of the traction 39 and its both ends in the the conveying system extends to the outside, so the traction vitro segment 21 has two ends in vitro. 当需要锁定封堵器时,同时拽拉该牵引段21的两个体外端,使得长条形锁定件31b随着牵引段21同时运动,随着长条形锁定件31b完全通过紧固件23上的通道24,并约束封堵器达到理想的形态时,然后再释放牵引段21的其中任意一个体外端,拽拉另一体外端,牵引段21的另一体外端会通过通孔39,最终脱离长条形锁定件31b,直至整根牵引段21被完全撤出体外。 When the occluder to be locked, while pulling the two pulled vitro end section 21 such that the elongated locking member 31b with simultaneous movement of the traction section 21, with the elongate locking member 23 by a fastener 31b is completely when the channel 24, and constrain the occluder to achieve the desired shape, and then release the traction section 21 wherein any one of the outer end, the outer end of the other pulled, pulling the other end of segment 21 would in vitro through the through hole 39, final departing elongated locking member 31b, until the entire root portion 21 is fully withdrawn traction vitro.

[0099] 以上仅为本发明的较佳实施例而已,并不用以限制本发明,凡在本发明的精神和原则之内所作的任何修改、等同替换和改进等,均应包含在本发明的保护范围之内。 [0099] The above description is only preferred embodiments of the present invention but are not intended to limit the present invention, any modifications within the spirit and principle of the present invention, equivalent substitutions and improvements should be included in the present invention. within the scope of protection.

Claims (13)

1.一种带锁定机构的封堵器,包括近端封堵单元、与所述近端封堵单元相连的远端封堵单元、设于所述近端封堵单元近端的紧固件、以及锁定机构;其特征在于:所述远端封堵单元设有网格框架;所述紧固件具有与所述近端封堵单元相通的通道;所述锁定机构包括锁丝和锁定件,所述锁定件与所述锁丝相连且可动地设于所述远端封堵单元和所述近端封堵单元合围形成的空间内,所述锁丝穿过所述网格框架后穿过所述通道,拉动所述锁丝带动所述远端封堵单元压缩所述近端封堵单元,且把所述锁定件移至所述通道外后,所述锁定件由所述紧固件抵挡。 1. A tape locking mechanism of the occluder, the occluder includes a proximal section, a distal section connected to said proximal occluder blocking means provided on the proximal end of the proximal fastener closure means , and a locking mechanism; characterized in that: said distal occluder element is provided with a grid frame; said fastener closure means having a passage communicating with said proximal end; said locking mechanism includes a locking member and a locking wire after said locking member and said lock wire is connected and movably disposed in the distal end of the proximal occluder and occluder means unit cooperatively define a space, said lock wire through said grid frame through the passage, pulling the distal end of the lock wire driving means compresses the occluder proximal end closure means and said locking member moves outside of the passage, the tightening of the locking member by the firmware resist.
2.如权利要求1所述的带锁定机构的封堵器,其特征在于:所述锁丝包括均与所述锁定件相连的锁定段和牵引段;所述锁定段穿过所述网格框架;所述牵引段穿过所述通道。 2. The belt as claimed in claim 1 occluder locking mechanism, characterized in that: said lock wire comprises both the locking member and a locking section coupled to the traction section; said locking segment through the grid a frame; the pulling section through the channel.
3.如权利要求2所述的带锁定机构的封堵器,其特征在于:所述锁定件上设有通孔,所述牵引段穿过所述通孔与所述锁定件相连。 3. A belt as claimed in claim 2, the occluder locking mechanism, characterized in that: said locking member is provided with a through hole, said traction member is connected to the section through the locking through hole.
4.如权利要求2或3所述的带锁定机构的封堵器,其特征在于:所述锁定件包括两个锁定球,每个所述锁定球的直径小于所述通道的最小直径,且所述两个锁定球的直径之和大于所述通道的近端直径;所述锁定段的两端分别与一个所述锁定球相连,所述牵引段分为两根,每一根牵引段的一端与一个所述锁定球相连,另一端穿过所述通道;所述封堵器的总高度大于所述锁定段总长度的二分之一。 4. The belt of claim 2 or claim 3 occluder locking mechanism, characterized in that: the minimum diameter of the locking member comprises two balls, each ball is smaller than the diameter of the locking of the locking of the channel, and locking the two ball diameter greater than the diameter of the proximal end of the channel; the locking end sections respectively connected to one of said locking ball, pulling the segment is divided into two, each of the traction segment one end of the locking ball and the other end of the through passage; the obturator is greater than the total height of the lock half of the total length of the segments.
5.如权利要求4所述的带锁定机构的封堵器,其特征在于:所述锁定件进一步包括连接在所述牵引段上的调节球;每个调节球的直径均小于所述通道的最小直径,且所述两个调节球的直径之和或者任意一个所述锁定球与任意一个调节球的直径之和均大于所述通道的近端直径;所述封堵器的总高度大于一根所述牵引段上的所述锁定球和所述调节球中的一个与另一根所述牵引段上的所述锁定球和所述调节球中的一个之间的锁丝长度的二分之一。 5. The belt as claimed in claim 4, wherein the locking mechanism occluder, characterized in that: further comprising a member connected to the pulling of the locking ball adjusting section; adjusting the diameter of each ball is less than the channel minimum diameter, and the diameter of the two balls with any or any one of the locking and adjusting a regulating balls and ball diameter greater than the diameter of the proximal end of the channel; total height of the obturator is greater than a the upper root section of the traction balls and a locking ball and the other on the adjustment of the segments of the locking ball and the traction regulating filament length dichotomy between the lock ball in a one.
6.如权利要求2或3所述的带锁定机构的封堵器,其特征在于:所述锁定件呈长条形;所述锁定段的一端连接所述锁定件的长边侧,另一端穿过所述网格框架后与所述紧固件的远端相连;所述牵引段的一端连接所述`锁定件的短边侧,另一端穿过所述通道;所述封堵器的总高度大于所述锁定段的总长度的二分之一。 6. The belt of claim 2 or claim 3 occluder locking mechanism, characterized in that: said locking member elongated strip; end of the locking section is connected to the long side of the locking member, the other end after passing through the mesh frame is connected to the distal end of the fastener; the traction section end is connected to the short side of the `locking member, the other end of the through passage; said occluder the total height is greater than half of the total length of the locking segments.
7.如权利要求2或3所述的带锁定机构的封堵器,其特征在于:所述锁定件呈长条形;所述锁定段的两端均连接所述锁定件的长边侧;所述牵引段的一端连接所述锁定件的短边侦U,另一端穿过所述通道;所述封堵器的总高度大于所述锁定段的总长度的二分之一。 7. The belt of claim 2 or claim 3 occluder locking mechanism, characterized in that: said locking member elongated strip; locking said end sections are connected long side of the locking member; the traction section end is connected to the short side of the locking member investigation U, the other end of the through passage; the obturator is greater than the total height of the lock half of the total length of the segments.
8.如权利要求2或3所述的带锁定机构的封堵器,其特征在于:所述锁定件呈长条形;所述锁定段为闭合结构,在所述锁定件的长边侧穿过所述锁定件;所述牵引段的一端连接所述锁定件的短边侧,另一端穿过所述通道;所述封堵器的总高度大于所述锁定段的总长度的二分之一。 8. The belt of claim 2 or claim 3 occluder locking mechanism, characterized in that: said locking member elongated strip; said locking segment is closed configuration, wear of the long side of the locking member through the locking member; end of the traction section is connected to the short side of the locking member, the other end of the through passage; said occluder overall height greater than the total length of the locking section one-half One.
9.如权利要求1所述的带锁定机构的封堵器,其特征在于:所述紧固件包括外套筒、以及嵌设在所述外套筒内的内套筒;编织所述网格框架的丝固定在所述内套筒与所述外套筒之间的间隙内。 9. The belt as claimed in claim 1, the locking of the occluder mechanism, wherein: the fastener comprises an outer sleeve, and outer sleeve embedded in said inner sleeve; said woven mesh wire grid frame is fixed in the gap between the inner sleeve and the outer sleeve.
10.如权利要求1所述的带锁定机构的封堵器,其特征在于:所述紧固件还设有与所述通道相通的凹槽;所述锁定件拉出所述通道后收容于所述凹槽内。 10. The belt as claimed in claim 1, said occluder locking mechanism, characterized in that: the fastener is also provided with a groove communicating with said passage; said rear locking member received in said passage drawn the recess.
11.如权利要求1所述的带锁定机构的封堵器,其特征在于:所述封堵器还包括位于所述远端封堵单元和所述近端封堵单元合围形成的空间内的弹性漏斗,所述弹性漏斗的漏斗口朝向远端,所述弹性漏斗通过漏嘴在所述通道的远端与所述通道连通。 11. The belt as claimed in claim 1, said occluder locking mechanism, characterized in that: the obturator further comprises a space at the distal occluder element and the proximal end of the closure means cooperatively define an elastic funnel, the funnel mouth elastic funnel toward the distal end, the distal end of the elastic funnel in communication with said drain passage through said channel mouth.
12.如权利要求1所述的带锁定机构的封堵器,其特征在于:所述近端封堵单元内、所述远端封堵单元内以及所述远端封堵单元与所述近端封堵单元的连接部内均设有阻流膜;且所述近端封堵单元内和所述连接部内的所述阻流膜上设有用于通过所述锁定件的孔。 12. The belt as claimed in claim 1 occluder locking mechanism, characterized in that: said proximal end of inner sealing means, said sealing means and the distal end of the inner blocking unit and the distal end near inner connecting end portion are provided with blocking means flow blocking film; and the proximal end of the occluder within the baffle means and the connection film portion is provided with inner through holes for the locking member.
13.如权利要求1所述的带锁定机构的封堵器,其特征在于:所述封堵器由生物相容的高分子材料制成。 13. A belt as claimed in claim 1, said occluder locking mechanism, characterized in that: the occluder is made of a biocompatible polymer material.
CN201310659952.XA 2013-12-06 2013-12-06 Occluder with locking mechanism CN103654883B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201310659952.XA CN103654883B (en) 2013-12-06 2013-12-06 Occluder with locking mechanism

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201310659952.XA CN103654883B (en) 2013-12-06 2013-12-06 Occluder with locking mechanism

Publications (2)

Publication Number Publication Date
CN103654883A true CN103654883A (en) 2014-03-26
CN103654883B CN103654883B (en) 2017-01-04

Family

ID=50294483

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201310659952.XA CN103654883B (en) 2013-12-06 2013-12-06 Occluder with locking mechanism

Country Status (1)

Country Link
CN (1) CN103654883B (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104287803A (en) * 2014-07-04 2015-01-21 先健科技(深圳)有限公司 Occluder and occlusion device
CN108236479A (en) * 2016-12-26 2018-07-03 上海微创医疗器械(集团)有限公司 Left aurcle plugging system, left aurcle plugging device and conveyor thereof
WO2018184438A1 (en) * 2017-04-06 2018-10-11 先健科技(深圳)有限公司 Occluder and occlusion device

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004069055A2 (en) * 2003-02-04 2004-08-19 Ev3 Sunnyvale Inc. Patent foramen ovale closure system
US20070118176A1 (en) * 2005-10-24 2007-05-24 Opolski Steven W Radiopaque bioabsorbable occluder
US20080077180A1 (en) * 2006-09-26 2008-03-27 Nmt Medical, Inc. Scaffold for tubular septal occluder device and techniques for attachment
CN101257852A (en) * 2005-07-07 2008-09-03 科迪斯公司 Patent foramen oval closure device with steerable delivery system
CN102149424A (en) * 2008-09-11 2011-08-10 Aga医药有限公司 Device for occluding vascular defects
CN202458502U (en) * 2012-03-21 2012-10-03 张湘鲁 Symmetrical heart interventricular septum plugging device
US20120316602A1 (en) * 2004-05-07 2012-12-13 W.L. Gore & Associates, Inc. Catching Mechanisms for Tubular Septal Occluder
CN203576563U (en) * 2013-12-06 2014-05-07 先健科技(深圳)有限公司 Plugging device with locking mechanism

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004069055A2 (en) * 2003-02-04 2004-08-19 Ev3 Sunnyvale Inc. Patent foramen ovale closure system
US20120316602A1 (en) * 2004-05-07 2012-12-13 W.L. Gore & Associates, Inc. Catching Mechanisms for Tubular Septal Occluder
CN101257852A (en) * 2005-07-07 2008-09-03 科迪斯公司 Patent foramen oval closure device with steerable delivery system
US20070118176A1 (en) * 2005-10-24 2007-05-24 Opolski Steven W Radiopaque bioabsorbable occluder
US20080077180A1 (en) * 2006-09-26 2008-03-27 Nmt Medical, Inc. Scaffold for tubular septal occluder device and techniques for attachment
CN102149424A (en) * 2008-09-11 2011-08-10 Aga医药有限公司 Device for occluding vascular defects
CN202458502U (en) * 2012-03-21 2012-10-03 张湘鲁 Symmetrical heart interventricular septum plugging device
CN203576563U (en) * 2013-12-06 2014-05-07 先健科技(深圳)有限公司 Plugging device with locking mechanism

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104287803A (en) * 2014-07-04 2015-01-21 先健科技(深圳)有限公司 Occluder and occlusion device
CN108236479A (en) * 2016-12-26 2018-07-03 上海微创医疗器械(集团)有限公司 Left aurcle plugging system, left aurcle plugging device and conveyor thereof
WO2018184438A1 (en) * 2017-04-06 2018-10-11 先健科技(深圳)有限公司 Occluder and occlusion device
CN108685599A (en) * 2017-04-06 2018-10-23 先健科技(深圳)有限公司 Packer and sealing device

Also Published As

Publication number Publication date
CN103654883B (en) 2017-01-04

Similar Documents

Publication Publication Date Title
US6206907B1 (en) Occlusion device with stranded wire support arms
AU2008292790B2 (en) Closure medical device
EP1844797B1 (en) Yarns containing thermoplastic elastomer copolymer and polyolefin filaments
EP2223657B1 (en) Device for suturing intracardiac defects
JP4210602B2 (en) Intravascular flow rate restricting device
US8992545B2 (en) Implant-catheter attachment mechanism using snare and method of use
US4981149A (en) Method for suturing with a bioabsorbable needle
US8764848B2 (en) Occluder device double securement system for delivery/recovery of such occluder device
US9259225B2 (en) Medical devices for treating a target site and associated method
US6966916B2 (en) Device and method for surgical repair of abdominal wall hernias
US8945211B2 (en) Tissue plication device and method for its use
DE60119944T2 (en) splintvorrichtungen endovascular
US5178629A (en) Method of forming a suture knot
US5074874A (en) Suture devices particularly useful in endoscopic surgery
EP2074953B1 (en) Percutaneous catheter directed intravascular occlusion devices
US9456811B2 (en) Vascular closure methods and apparatuses
EP2152171B1 (en) Loader and threader for knotting element
US4932962A (en) Suture devices particularly useful in endoscopic surgery and methods of suturing
US7875052B2 (en) Tissue closure and tissue closing device
EP1929961B1 (en) Knotless wound closure device
AU2005299369B2 (en) Yarns containing filaments made from shape memory alloys
US8029534B2 (en) Closure device with string retractable umbrella
CN102166124B (en) And manufacturing method occluder
CN101257852B (en) Patent foramen oval closure device with steerable delivery system
US20050187568A1 (en) Devices and methods for closing a patent foramen ovale with a coil-shaped closure device

Legal Events

Date Code Title Description
C10 Entry into substantive examination
C41 Transfer of patent application or patent right or utility model
C14 Grant of patent or utility model