CN108211137A - A kind of compact rotary frame for proton therapeutic - Google Patents

A kind of compact rotary frame for proton therapeutic Download PDF

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Publication number
CN108211137A
CN108211137A CN201810071324.2A CN201810071324A CN108211137A CN 108211137 A CN108211137 A CN 108211137A CN 201810071324 A CN201810071324 A CN 201810071324A CN 108211137 A CN108211137 A CN 108211137A
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CN
China
Prior art keywords
deflection magnet
deflection
rotary frame
magnet
proton therapeutic
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201810071324.2A
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Chinese (zh)
Inventor
张满洲
陈沅
方守贤
李德明
赵振堂
杜涵文
吴军
殷重先
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Shanghai Alliance Investment Ltd
Shanghai Institute of Applied Physics of CAS
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Shanghai Institute of Applied Physics of CAS
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Priority to CN201810071324.2A priority Critical patent/CN108211137A/en
Publication of CN108211137A publication Critical patent/CN108211137A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1077Beam delivery systems
    • A61N5/1081Rotating beam systems with a specific mechanical construction, e.g. gantries
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N2005/1085X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy characterised by the type of particles applied to the patient
    • A61N2005/1087Ions; Protons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N2005/1092Details

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Magnetic Treatment Devices (AREA)
  • Radiation-Therapy Devices (AREA)

Abstract

The present invention relates to a kind of compact rotary frames for proton therapeutic, with the deflection magnet with magnetic field gradient, the deflection magnet is made of the first deflection magnet and the second deflection magnet, two blocks of quadrupole iron for optical match are installed before the first deflection magnet, four blocks of quadrupole iron for optical match are installed between the first deflection magnet and the second deflection magnet, wherein, at least the second deflection magnet be segmentation structure, every section of gradient difference.It is according to the present invention to reduce rotary frame size for the compact rotary frame of proton therapeutic, reduce rotary frame weight so that manufacture and install it is simpler, reduce production cost and operation power consumption.

Description

A kind of compact rotary frame for proton therapeutic
Technical field
The present invention relates to proton therapeutics, relate more specifically to a kind of compact rotary frame for proton therapeutic.
Background technology
Accurate and conformal radiation therapy technology is proved to be using the radiotherapy of proton, it can be by high dose proton Target area is transported to, while minimizes the dosage around health tissues.
Proton therapy equipment includes accelerator and transit, wherein, the accelerator is for generating high energy proton, the transit For proton beam to be transported to target from multiple radiation direction.Rotary frame is a kind of support machine of known rotation beam transit Structure, target are positioned in the consolidating of limiting of intersecting by the export center axis of the rotation axis and last block deflection magnet of rotary frame Positioning is put, which also referred to as waits centers.
Traditional rotary frame structure as seen in figure la and lb, including several deflection magnets 1 and quadrupole iron 2.Obviously, should The longitudinal length of traditional rotary frame is longer, very big so as to cause weight.General rotary frame weight is high in the world at present Up to more than 100 tons.It is analyzed from rotary frame weight composition, the weight of magnet accounts for about 1/5 or so, remaining most of weight is branch Frame construction weight in itself and counterweight.Therefore, cable architecture is transported by changing, although the quantity of magnet may be increased or changed Become the quantity of bending magnet, that is, magnet weight may be increased, still, since magnet weight only accounts for rotary frame total weight 1/5, the total weight of rotary frame is it is possible that reduce.In order to ensure that the beam center in rotation process waits centers from above-mentioned Error be maintained in the range of very little, that is, reduce rotation caused by line position in target area variation, rotating The deformation requirements of entire stent are controlled in the range of very little in journey, and last block deflection magnet is with a distance from support shaft and weight It determines the maximum torque of deformation, therefore reduces weight support frame there are two approach, one is the radius of turn of stent is reduced, secondly It is the longitudinal length for reducing stent.
CN104105527A discloses a kind of small-sized, light weight pallet and the particle beam therapeutic apparatus using the pallet, leads to The radius of turn of over-subtraction limited bracket reaches light-weighted purpose.But due to the program using sweeping magnet mounted on last Before one block of deflection magnet, it is very big to cause last block deflection magnet gap, and weight is extremely heavy, this also has led to entirely rotating The reduction of the total weight of rack is not obvious.
CN201720221304.X proposes a kind of optimization structure of compact rotary frame, uses three blocks of deflection magnets Structure so that rotating part heavier-weight, second and the gap of third deflection magnet can also increase the length of rotary frame.This Outside, longer treatment head so that its SAD is larger, causes radius of turn larger, considerably increases the weight of rotary frame.
Invention content
The present invention is intended to provide a kind of compact rotary frame for proton therapeutic, passes through the longitudinal length for reducing stent To mitigate the total weight for rotating integrally rack.
A kind of compact rotary frame for proton therapeutic of the present invention has the deflection magnetic with magnetic field gradient Iron, the deflection magnet are made of the first deflection magnet and the second deflection magnet, are equipped with before the first deflection magnet for optics Matched two blocks of quadrupole iron is equipped with four pieces of quadrupoles for optical match between the first deflection magnet and the second deflection magnet Iron, wherein, at least the second deflection magnet be segmentation structure, every section of gradient difference.
Treatment head for scanning or scattering is mounted on the position after the second deflection magnet.
There is gradient between first deflection magnet and the second deflection magnet.
Segmentation structure is respectively adopted in first deflection magnet and the second deflection magnet.
First deflection magnet and the second deflection magnet respectively have gradient.
First deflection magnet is unistage type structure, and the second deflection magnet is three stage structure.
First deflection magnet is two-part structure, and the second deflection magnet is four-part form structure.
First deflection magnet and the second deflection magnet are the deflection magnet for turning 90 degrees proton beam total partially.
The present invention shortens the longitudinal length of rotary frame by the deflection magnet with gradient, reduces the number of quadrupole iron, In addition, the use with gradient deflection magnet, can greatly reduce the envelope function in transmission process, so that deflection magnet Aperture reduces, and weight reduces.Although with gradient deflection magnet there is gradient to lock and cannot arbitrarily adjust with deflection magnet field strength Adjusting, still, the present invention by the combination of the gradient and quadrupole iron intensity that design deflection magnet forms it into 1:1 transmission requirement Rotary frame (i.e.《The beam optics design of proton therapeutic beam match system based on Geant4 simulations》The rack designed in text, Referring to《Nuclear technology》, 2013,36 (7), 21-25 pages), since transmission matrix M is 1:1, it is not needed in different angle to focusing on Intensity is adjusted, it is only necessary to is adjusted in synchronism when transmitting different-energy with deflection magnet, ideally avoid band gradient and deflect magnetic The weakness of iron.Moreover, the first deflection magnet and the second deflection magnet, using amounting to 90 degree, reasonably selecting every piece of rotation angle can Not only to reduce the longitudinal length of rotary frame, but also reduce the weight of rotary frame.It can using shorter compact scanning treatment head It is greatly shortened so as to export to isocentric distance from the second deflection magnet, so as to reduce the radius of rotary frame, reaches reduction The purpose of torque and support section weight.In short, according to the present invention reduce for the compact rotary frame of proton therapeutic Rotary frame size reduces rotary frame weight so that manufacture and install it is simpler, reduce production cost and operation work( Consumption.
Description of the drawings
Fig. 1 a and Fig. 1 b are rotary frame structure schematic diagrames of the prior art;
Fig. 2 is rotary frame structure figure according to a preferred embodiment of the present invention;
Fig. 3 is the envelope function schematic diagram of the rotary frame of Fig. 2;
Fig. 4 is rotary frame structure figure according to a further advantageous embodiment of the invention;
Fig. 5 is the envelope function schematic diagram of the rotary frame of Fig. 4.
Specific embodiment
Below in conjunction with the accompanying drawings, presently preferred embodiments of the present invention is provided, and is described in detail.
The whirler according to a preferred embodiment of the present invention of the angle perpendicular to horizontal plane is in shown in Fig. 2 Frame, has the first deflection magnet 11 and the second deflection magnet 12, which carries magnetic field gradient.First deflection magnet 11 It is useful for two blocks of quadrupole iron 21,22 of optical match before, this two blocks of quadrupole iron 21,22 is not take up rotating weight, and positioned at rotation Shaft in the heart, does not increase rotary frame longitudinal length, can increase matched flexibility.First deflection magnet 11 and second is inclined Turn that four blocks of quadrupole iron 23,24,25,26 for optical match are installed between magnet 12.For the treatment head for scanning or scattering (not shown) is mounted on the position after the second deflection magnet 12, ensures that (equivalent source is away from slightly smaller than the second deflection magnet 12 by SAD Outlet is away from isocentric distance) obtain preferable therapeutic effect more than 2.3 meters.No matter the rack uses barrel type, frame-type also It is girder structure, shorter longitudinal length and smaller radius of turn can be obtained.Wherein, the second deflection magnet is segmented Structure, every section has different gradients.In the present embodiment, which is divided into 3 sections.
By carefully optimizing the hop count of deflection magnet 11,12 and every section of gradient and quadrupole iron 21,22,23,24,25,26 Intensity, obtain from rotary frame entrance 00 to wait centers 01 transmission matrix be 1:1 a set of optical characteristics, and meet De-dispersion condition at the centers of grade ensures in entire transmission process line envelope (3sigma) less than 6mm, envelope function such as Fig. 3 institutes Show, than《The beam optics design of proton therapeutic beam match system based on Geant4 simulations》Envelope function smaller in text, so as to Substantially reduce aperture and the weight of deflection magnet 11,12 and quadrupole iron 21,22,23,24,25,26.Centers 01 are waited in order to reach The beam spot size of position can reconcile to be remained unchanged in each rotation angle of rotary frame, and beam spot ruler is needed at rotary frame entrance 00 It is very little to be adjusted to be round, and according to the shapes and sizes for the treatment of requirement.The horizontal and vertical coupling that rotation is brought is excluded in this way There are more quadrupole iron to be easier to match the beam spot size for the treatment of requirement after conjunction, and on transit.Compared to old rotation Rack needs to meet that horizontal and vertical emittance is identical, mutually equal maximum of condition loosens envelope function.
Fig. 4 gives one kind and is more preferably laid out, and has the first deflection magnet 110 and the second deflection magnet 120, the deflection Magnet carries magnetic field gradient.Two blocks of quadrupole iron 210,220 of optical match are useful for before first deflection magnet 110.First partially Turn that four blocks of quadrupole iron 230,240,250,260 for optical match are installed between 110 and second deflection magnet 120 of magnet. Difference lies in the first deflection magnets 110 to be divided into 2 sections, and the second deflection magnet 120 is divided into 4 sections, obtains than the envelope letter in Fig. 3 Number smaller, it is meant that the reduction of magnet gap and weight.
In short, the compact rotary frame backbone mark according to the present invention for proton therapeutic is by two pieces of deflection magnet groups Into they are sequentially arranged in beam transfer plane, and the first and second deflection magnets utilize opposite magnetic direction, and line is inclined It goes on the track vertical with former line.Quadrupole iron auxiliary control line envelope is installed to press between this two blocks of deflection magnets Contracting magnet gap.The compact rotary frame for being used for proton therapeutic reduces longitudinal direction using the superelevation field strength deflection magnet with gradient Size;Using compact scanning treatment head, radius of turn is reduced;Reduce magnet weight;Simultaneously meet from the inlet to the outlet 1:1 transmission, reduces regulated quantity.Wherein, amounting to 90 degree of deflection magnets using two pieces causes longitudinal size to reduce, magnet total weight It reduces.1 is both realized by the combination of the gradient and quadrupole iron intensity that design deflection magnet:The envelope letter of line is compressed in 1 transmission again Number so that the gap that deflection magnet needs reduces, so as to reduce the weight of deflection magnet.The reduction of deflection magnet weight is again into one Step waits the rack weight needed for errors of centration to reduce so that maintaining like.
Above-described, only presently preferred embodiments of the present invention is not limited to the scope of the present invention, of the invention is upper Stating embodiment can also make a variety of changes, and such as the first deflection iron is one section, and the second deflection iron is four sections of even more multistages.It is i.e. all It is claims for applying according to the present invention and simple, equivalent changes and modifications that description is made, falls within this hair The claims of bright patent.The not detailed description of the present invention is routine techniques content.

Claims (8)

1. a kind of compact rotary frame for proton therapeutic, which is characterized in that this is used for the compact rotation of proton therapeutic Rack has the deflection magnet with magnetic field gradient, which is made of the first deflection magnet and the second deflection magnet, and first Two blocks of quadrupole iron for optical match before deflection magnet are installed, are installed between the first deflection magnet and the second deflection magnet Be useful for four blocks of quadrupole iron of optical match, wherein, at least the second deflection magnet be segmentation structure, every section of gradient difference.
2. the compact rotary frame according to claim 1 for proton therapeutic, which is characterized in that for scanning or dissipating The treatment head penetrated is mounted on the position after the second deflection magnet.
3. the compact rotary frame according to claim 1 for proton therapeutic, which is characterized in that the first deflection magnetic There is gradient between iron and the second deflection magnet.
4. the compact rotary frame according to claim 1 for proton therapeutic, which is characterized in that the first deflection magnetic Segmentation structure is respectively adopted in iron and the second deflection magnet.
5. the compact rotary frame according to claim 4 for proton therapeutic, which is characterized in that the first deflection magnetic Iron and the second deflection magnet respectively have gradient.
6. the compact rotary frame according to claim 4 for proton therapeutic, which is characterized in that the first deflection magnetic Iron is unistage type structure, and the second deflection magnet is three stage structure.
7. the compact rotary frame according to claim 4 for proton therapeutic, which is characterized in that the first deflection magnetic Iron is two-part structure, and the second deflection magnet is four-part form structure.
8. the compact rotary frame according to claim 1 for proton therapeutic, which is characterized in that the first deflection magnet With the second deflection magnet for proton beam is amounted to the deflection magnet turning 90 degrees partially.
CN201810071324.2A 2018-01-25 2018-01-25 A kind of compact rotary frame for proton therapeutic Pending CN108211137A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111249633A (en) * 2020-03-21 2020-06-09 华中科技大学 High momentum acceptance superconducting rotating gantry for proton therapy
CN114796895A (en) * 2022-04-11 2022-07-29 中国科学院近代物理研究所 Terminal treatment system based on 90-degree rotating beam line and operation method thereof

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH08257148A (en) * 1995-03-24 1996-10-08 Hitachi Ltd Rotary gantry
JPH1094617A (en) * 1996-09-24 1998-04-14 Toshiba Corp Accelerator irradiation apparatus for radiotherapy
CN106139419A (en) * 2016-07-29 2016-11-23 中国原子能科学研究院 For treating the rotary frame of tumor
CN106669050A (en) * 2017-03-08 2017-05-17 中国科学院上海应用物理研究所 Compact rotating frame
CN206759798U (en) * 2017-05-12 2017-12-15 合肥中科离子医学技术装备有限公司 A kind of compact proton beam energy and energy spread control structure
CN208493023U (en) * 2018-01-25 2019-02-15 中国科学院上海应用物理研究所 A kind of compact rotary frame for proton therapeutic

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH08257148A (en) * 1995-03-24 1996-10-08 Hitachi Ltd Rotary gantry
JPH1094617A (en) * 1996-09-24 1998-04-14 Toshiba Corp Accelerator irradiation apparatus for radiotherapy
CN106139419A (en) * 2016-07-29 2016-11-23 中国原子能科学研究院 For treating the rotary frame of tumor
CN106669050A (en) * 2017-03-08 2017-05-17 中国科学院上海应用物理研究所 Compact rotating frame
CN206759798U (en) * 2017-05-12 2017-12-15 合肥中科离子医学技术装备有限公司 A kind of compact proton beam energy and energy spread control structure
CN208493023U (en) * 2018-01-25 2019-02-15 中国科学院上海应用物理研究所 A kind of compact rotary frame for proton therapeutic

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111249633A (en) * 2020-03-21 2020-06-09 华中科技大学 High momentum acceptance superconducting rotating gantry for proton therapy
CN114796895A (en) * 2022-04-11 2022-07-29 中国科学院近代物理研究所 Terminal treatment system based on 90-degree rotating beam line and operation method thereof

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