CN108210860A - Invigorating the spleen to arrest diarrhea preparation - Google Patents

Invigorating the spleen to arrest diarrhea preparation Download PDF

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CN108210860A
CN108210860A CN201611203937.4A CN201611203937A CN108210860A CN 108210860 A CN108210860 A CN 108210860A CN 201611203937 A CN201611203937 A CN 201611203937A CN 108210860 A CN108210860 A CN 108210860A
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rhizoma
chinese medicine
spleen
rhizoma atractylodis
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董早霞
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • A61K36/9068Zingiber, e.g. garden ginger
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/07Basidiomycota, e.g. Cryptococcus
    • A61K36/076Poria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/284Atractylodes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/34Campanulaceae (Bellflower family)
    • A61K36/344Codonopsis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481Astragalus (milkvetch)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/54Lauraceae (Laurel family), e.g. cinnamon or sassafras
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/57Magnoliaceae (Magnolia family)
    • A61K36/575Magnolia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/68Plantaginaceae (Plantain Family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/752Citrus, e.g. lime, orange or lemon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/884Alismataceae (Water-plantain family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/894Dioscoreaceae (Yam family)
    • A61K36/8945Dioscorea, e.g. yam, Chinese yam or water yam
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/899Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • A61K36/8994Coix (Job's tears)

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  • Health & Medical Sciences (AREA)
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Abstract

The invention discloses one kind for treating chronic colitis innerwear Chinese medicine preparation, which is characterized in that the Chinese medicine material and parts by weight of selection be respectively:10 grams of rhizoma atractylodis, 6 grams of Cortex Magnoliae Officinalis, 10 grams of dried orange peel, 15 grams of Radix Astragali, 15 grams of Radix Codonopsis, 15 grams of Poria cocos, 15 grams of Rhizoma Atractylodis Macrocephalae, 30 grams of Chinese yam, 15 grams of rhizoma alismatis, 30 grams of coix seed, 30 grams of plantain seed, 10 grams of rhizoma zingiberis, 6 grams of cassia twig.Raw medicinal material pharmacological property effect selected by the present invention is complementary, evaded the mutual inhibition of compatibility between drug, mutual restraint between two drugs, the mutual-detoxication choosing, make drug mutual reinforcement between, mutually make effect notable, there is strengthening the spleen and replenishing qi, dampness removing antidiarrheal.Oral administration for treating chronicity colitis has definite curative effect.

Description

Invigorating the spleen to arrest diarrhea preparation
Technical field
The present invention relates to the field of Chinese medicines, and in particular to a kind of invigorating the spleen to arrest diarrhea preparation, for treating during chronic colitis takes orally Medicine preparation has effects that strengthening the spleen and replenishing qi, dampness removing antidiarrheal.
Background technology
Chronic colitis is a kind of cause of disease colon still not fully aware of and rectum chronic nonspecific inflammation disease, disease Change is confined to colorectal mucosa and submucosa.Lesion multidigit also may extend to colon descendens or even entire in sigmoid colon and rectum Colon.The course of disease is very long, normal recurrent exerbation.The unknown colon chronic inflammation of other reasons should be directed on the basis of the clear and definite cause of disease The diagnosis and treatment of property ground.The initial performance of chronic ulcerative colitis can be there are many form.Bloody diarrhea is most common early symptom.Its His symptom have successively abdominal pain, have blood in stool, weight loss, it is tenesmus, vomiting etc..It is mainly shown as arthritis, iris ciliary once in a while Body is scorching, hepatosis and cutaneous lesions.It is a uncommon sign that fever is then opposite, this disease shows in Most patients It is in acute, the calamitous process broken out in small number of patients (accounting for about 15%) to be chronic, low pernicious.These patients show as frequency Numerous courage and uprightness excrement, can up to 30 times/day and high fever, abdominal pain.Sign is directly related with stadium and clinical manifestation, and patient often has Weight loss and pale complexion, in disease activity phase abdomen examination, colon site often has tenderness.There may be acute abdomen sign companion Fever and gurgling sound are reduced, particularly evident in acute attack or fulminant type case.Can have during toxic megacolon abdominal distension, fever and Acute abdomen sign.Due to frequent diarrhea, anal skin can have scratch, strip off.Crissum inflammation such as anal fissure or anal fistula can also occur.Directly Intestines refer to inspection sense pain.Skin, mucous membrane, tongue, the inspection of joint and eye are particularly important.
Invention content
The present invention relates to the field of Chinese medicines, and in particular to one kind has strong for treating chronic colitis innerwear Chinese medicine preparation The effect of spleen QI invigorating, dampness removing antidiarrheal.It is for oral administration, it can be used for chronic colitis treatment, there is definite curative effect.
Present invention employs following technical solutions to achieve the above object:The medicinal material of Chinese medicine preparation selection of the present invention And parts by weight are respectively:10 grams of rhizoma atractylodis, 6 grams of Cortex Magnoliae Officinalis, 10 grams of dried orange peel, 15 grams of Radix Astragali, 15 grams of Radix Codonopsis, 15 grams of Poria cocos, 15 grams of Rhizoma Atractylodis Macrocephalae, 30 grams of Chinese yam, 15 grams of rhizoma alismatis, 30 grams of coix seed, 30 grams of plantain seed, 10 grams of rhizoma zingiberis, 6 grams of cassia twig.
In the Chinese medicine material that the present invention selects:Rhizoma atractylodis:Medicinal part, the dry rhizome of plant.Nature and flavor:Acrid flavour, hardship, property Temperature.Channel tropism, returns spleen, stomach, Liver Channel.Effect:It is drying damp and strengthening spleen, expelling wind and clearing away cold, improving eyesight.It cures mainly:For damp retention in middle-jiao, abdominal fullness and distention, Diarrhea, oedema, tinea pedis impotence are knitted, arthralgia pain due to rheumatism, anemofrigid cold, yctalopia, and eyes dusk is puckery.
Cortex Magnoliae Officinalis:【Nature and flavor】:It is bitter;It is pungent;It is warm-natured【Channel tropism】:The spleen channel;Stomach;Large intestine channel.【Function】:Gas consumption product;Eliminating dampness is removed It is full;Relieving asthma【It cures mainly】:Stagnation of QI due to dyspepsia;Abdominal distention constipation;Damp retention in middle-jiao, abdominal swelling and diarrhea;Phlegm stops up the circulation of vital energy in the wrong direction;Chest full of cough.
Dried orange peel:Dried orange peel contains hesperidine about 8.4%, Nobiletin (nobiletin) about 0.15%. separately containing synephrine (to hydroxyl Forint) 0.28%-2.54%.【Nature and flavor】It is bitter, acrid in flavour and warm in nature.【Channel tropism】Return lung, the spleen channel.【Attending effectiveness】:Regulating qi-flowing for strengthening spleen, it is dry in tune It is wet, resolving sputum.Cure mainly the abdominal fullness and distention of the taste stagnation of the circulation of vital energy or pain, indigestion.Abdominal distension uncomfortable in chest, indigestion and loss of appetite loose stool in wet turbid resistance.Phlegm The wet cough and asthma for stopping up lung.For chest gastral cavity turgor, deficiency of food is vomited and diarrhoea, coughing with a lot of sputum.
Radix Astragali:With invigorating qi for strengthening superficies, profit water detumescence, pus draining and toxin expelling, myogenic and other effects.Radix Astragali containing saponin, sucrose, polysaccharide, The various trace elements such as a variety of amino acid, folic acid and selenium, zinc, copper.Have enhancing body's immunity, liver protection, diuresis, anti-aging, Resisting stress, decompression and wide antibacterial action.
Radix Codonopsis:With tonifying middle-Jiao and Qi, the effect of strengthening spleen and tonifying lung.For spleen and lung weakness, shortness of breath and palpitation, anorexia and loose stool, void asthma Cough, Heat Diabetes etc..Meridian distribution of property and flavor:It is mild-natured, it is sweet in flavor, slightly sour.Returns spleen, lung channel.
Poria cocos:Property slightly sweet flavor is put down, and enters the heart, lung, the spleen channel.With eliminating dampness and diuresis, the effect of strengthening the spleen and stomach, antitoxic heart-soothing and sedative.Energy Enhance body's immunity, pachymaran has apparent antitumor and liver protecting effect.Difficult urination, oedema turgor, phlegm can be controlled It is inverse to drink cough, vomits inverse, vomiting during early pregnancy, diarrhea, seminal emission, stranguria with turbid discharge is palpitated with fear, forgetful to wait diseases.
Rhizoma Atractylodis Macrocephalae:【Meridian distribution of property and flavor】Bitter, sweet, warm.Returns spleen, stomach.Effect:Strengthening the spleen and replenishing qi, eliminate dampness and have diuretic effect, hidroschesis, tocolysis.With In spleen eating less, abdominal distention diarrhea, phlegm retention anti-dazzle nervous, oedema, spontaneous perspiration, fetal irritability.
Chinese yam:Have nourish it is strong, it is aid digestion, hold back abnormal sweating, the effect of antidiarrheal, cure mainly insufficiency of the spleen diarrhoea, cough due to deficiency of the lung, diabetes It quenches one's thirst, oliguria frequency, road essence, women is with lower and dyspeptic chronic enteritis.Nature and flavor:It is sweet, flat, nontoxic.Channel tropism:Returns spleen, lung, Kidney channel.Function:Tonifying spleen nourishing the stomach, engender liquid and benefic lung, the puckery essence of kidney tonifying.For spleen eating less, endless diarrhea, the deficiency syndrome of the lung is breathed with cough, emission due to the kidney deficiency, Under band, frequent micturition, abnormal heat is quenched one's thirst.Rhizoma Dioscoreae (parched with bran) good efficacy to suffering from a deficiency of the kidney.For spleen eating less, diarrhea loose stool, leukorrhea.
Rhizoma alismatis:Nature and flavor:It is sweet, it trembles with fear.Channel tropism:Enter kidney, bladder warp.Effect:Li Shui, excreting dampness expel the heat-evil.Control difficult urination, oedema Turgor, vomiting, rush down dysentery, phlegm and retained fluid, tinea pedis, gonorrhoea, hematuria.
Coix seed:Property slightly sweet flavor is slightly cold, and has inducing diuresis for removing edema, invigorating spleen to remove dampness, relaxing muscles and tendons eliminating impediment, clearing away heat and eliminating pus and other effects, is normal Damp-clearing drug.Adlay is a kind of beauty food again, and often feeding can keep human skin gloss fine and smooth, eliminate acne, sparrow Spot, senile plaque, cyasma, butterfly macules have good efficacy to furfur, acne, chap, pachylosis etc..【Major function】:It is strong Spleen excreting dampness, remove numbness antidiarrheal.Semen Coicis can be used for treatment oedema, tinea pedis, difficult urination, arthritis with fixed pain caused by dampness contraction, splenasthenic diarrhea.It is the clear of mitigation The product of hot clearing damp, the traditional Chinese medical science often use it to the illnesss such as treatment insufficiency of the spleen diarrhoea, muscle acid weight, arthralgia, oedema, tinea pedis.
Plantain seed:Nature and flavor:It is sweet;It is light;Cold nature.Channel tropism:It is distributed in lung channel;Liver Channel;Kidney channel;Bladder warp.Function:Reducing fever and causing diuresis; Excreting dampness antidiarrheal;Improving eyesight;Eliminating the phlegm.It cures mainly:Main difficult urination;Under stranguria with turbid discharge band;Oedema turgor;Summer-heat and damp rush down dysentery;Hot eyes is hidden from view;Phlegm heat-syndrome cough Asthma.
Rhizoma zingiberis:【Nature and flavor, channel tropism】Acrid flavour, property heat.Returns spleen, stomach, the heart, lung channel.【Effect】Warming spleen and stomach for dispelling cold, recover Yang and smooth venation are dry Wet dissolving phlegm, warming lung and resolving fluid.【It cures mainly】Coldness and pain in the epigastrium;Vomiting;Diarrhea, yang depletion are fainted inverse;Cold drink is breathed with cough;Numbness and ache of cold dampness.
Cassia twig:【It cures mainly】Expelling cold and relieving exterior syndrome;Warming meridian;Activating YANG and prormoting functioning of QI.Main exterior syndrome due to wind-cold;Numbness and ache of cold dampness;Peripheral coldness;Through Close dysmenorrhoea;Abdominal mass caking;The obstruction of qi in the chest;Palpitaition;Phlegm and retained fluid;Difficult urination.For anemofrigid cold, coldness and pain in the epigastrium, blood trembles with fear Amenorrhea, joint numbness Bitterly, phlegm and retained fluid, oedema, palpitaition, run quickly globefish.【Effect】Sweating expelling pathogenic factors from muscles and skin, warming meridians and promoting circulation of qi, helps yang transforming qi, eliminating cold to stop pain.
Raw medicinal material pharmacological property effect selected by the present invention is complementary, evaded the mutual inhibition of compatibility between drug, mutual restraint between two drugs, the mutual-detoxication it The effect of choosing, makes drug mutual reinforcement between, mutually makes effect notable, has and improves immunity, strengthening the spleen and replenishing qi, dampness removing antidiarrheal.Orally taken for curing is slow Property colitis, have definite curative effect.
Using of the present invention for treating chronic colitis innerwear Chinese medicine preparation, by clinical practice, achieve imaginary Less than promising result;
Drug therapy chronic colitis clinical observation of the present invention:
1. general information
Accept out-patient totally 40 for medical treatment, wherein man 30, female 10, the ratio between men and women be 20~30 years old 3: 1 age 3,31 ~40 years old 17,41~50 years old 10,50 years old or more 10.
It is as follows that 2. case is embodied:Lee XX, man, 56 years old.The big loose stool of readme is thin, number increased with more than ten years, when serious Defecate thin, day up to 6 times or more, over nearly two months because diet slightly it is cool stool it is thin, day up to 5 times or more, with receive it is poor, weak, Sallow complexion, dynamic then shortness of breath etc..Tongue nature is light, corpulent tongue, and deficient and weak pulse once did colonoscopy and shows:Chronic colitis.With throwing present invention side 7 doses of agent, takes daily 1 dose, divides 2 times sooner or later and warmly takes.As a treatment course to do decoction oral treatment, when examining again in the future, readme is defecated slightly thick, day Twice, it received food slightly once, and still had weak, sallow complexion, dynamic then shortness of breath.20 courses for the treatment of of following the service, all diseases are all removed.It is enjoined, continues to control It treats a course for the treatment of and consolidates curative effect.Take several doses i.e. more.
Specific embodiment
It is described to be used to treat chronic colitis innerwear Chinese medicine preparation, which is characterized in that the Chinese medicine material and parts by weight of selection It is respectively:10 grams of rhizoma atractylodis, 6 grams of Cortex Magnoliae Officinalis, 10 grams of dried orange peel, 15 grams of Radix Astragali, 15 grams of Radix Codonopsis, 15 grams of Poria cocos, 15 grams of Rhizoma Atractylodis Macrocephalae, Chinese yam 30 Gram, 15 grams of rhizoma alismatis, 30 grams of coix seed, 30 grams of plantain seed, 10 grams of rhizoma zingiberis, 6 grams of cassia twig;
Preparation method:10 grams of rhizoma atractylodis, 6 grams of Cortex Magnoliae Officinalis, 10 grams of dried orange peel, 15 grams of Radix Astragali, 15 grams of Radix Codonopsis, 15 grams of Poria cocos, Rhizoma Atractylodis Macrocephalae 15 Gram, 30 grams of Chinese yam, 15 grams of rhizoma alismatis, 30 grams of coix seed, 30 grams of plantain seed, 10 grams of rhizoma zingiberis, 6 grams of cassia twig;Medicine materical crude slice is respectively prepared, passes through Pressure cooker cooking disinfection 50-70 minutes, dries, and obtains aseptic raw material, is sealed packaging, obtains commodity Chinese medicine preparation drink Product.

Claims (2)

1. for treating chronic colitis innerwear Chinese medicine preparation, which is characterized in that the Chinese medicine material and parts by weight of selection be respectively: 10 grams of rhizoma atractylodis, 6 grams of Cortex Magnoliae Officinalis, 10 grams of dried orange peel, 15 grams of Radix Astragali, 15 grams of Radix Codonopsis, 15 grams of Poria cocos, 15 grams of Rhizoma Atractylodis Macrocephalae, 30 grams of Chinese yam, rhizoma alismatis 15 Gram, 30 grams of coix seed, 30 grams of plantain seed, 10 grams of rhizoma zingiberis, 6 grams of cassia twig.
2. treatment chronic colitis innerwear Chinese medicine preparation according to claim 1, it is characterised in that:Preparation method be with Lower step:
Step 1:Weigh raw medicinal material:10 grams of rhizoma atractylodis, 6 grams of Cortex Magnoliae Officinalis, 10 grams of dried orange peel, 15 grams of Radix Astragali, 15 grams of Radix Codonopsis, 15 grams of Poria cocos, 15 grams of Rhizoma Atractylodis Macrocephalae, 30 grams of Chinese yam, 15 grams of rhizoma alismatis, 30 grams of coix seed, 30 grams of plantain seed, 10 grams of rhizoma zingiberis, 6 grams of cassia twig;
Step 2:The medicine materical crude slice that will be obtained by pressure cooker cooking disinfection 50-70 minutes, dries, and obtains aseptic raw material;
Step 3:The aseptic raw material that will be obtained is sealed packaging, obtains commodity Chinese medicine preparation drink.
CN201611203937.4A 2016-12-12 2016-12-12 Invigorating the spleen to arrest diarrhea preparation Pending CN108210860A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106822683A (en) * 2017-04-11 2017-06-13 史逸凡 A kind of benefit holds back anti-diarrheal decoction and preparation method thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105395731A (en) * 2015-12-30 2016-03-16 刘建伟 Medicine for treating infantile diarrhea caused by improper diet and spleen depression

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105395731A (en) * 2015-12-30 2016-03-16 刘建伟 Medicine for treating infantile diarrhea caused by improper diet and spleen depression

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106822683A (en) * 2017-04-11 2017-06-13 史逸凡 A kind of benefit holds back anti-diarrheal decoction and preparation method thereof

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Application publication date: 20180629