CN108207932A - A kind of novel stem cells storage container - Google Patents

A kind of novel stem cells storage container Download PDF

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Publication number
CN108207932A
CN108207932A CN201711480810.1A CN201711480810A CN108207932A CN 108207932 A CN108207932 A CN 108207932A CN 201711480810 A CN201711480810 A CN 201711480810A CN 108207932 A CN108207932 A CN 108207932A
Authority
CN
China
Prior art keywords
liner
renovated
outer courage
stem cells
storage container
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201711480810.1A
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Chinese (zh)
Inventor
韩洪起
鲁振宇
张冰晶
徐悦
秦臻
王瑶
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tianjin Puri Purcell Biotechnology Co Ltd
Original Assignee
Tianjin Puri Purcell Biotechnology Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tianjin Puri Purcell Biotechnology Co Ltd filed Critical Tianjin Puri Purcell Biotechnology Co Ltd
Priority to CN201711480810.1A priority Critical patent/CN108207932A/en
Publication of CN108207932A publication Critical patent/CN108207932A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02Preservation of living parts
    • A01N1/0236Mechanical aspects
    • A01N1/0242Apparatuses, i.e. devices used in the process of preservation of living parts, such as pumps, refrigeration devices or any other devices featuring moving parts and/or temperature controlling components

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  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Thermal Sciences (AREA)
  • Mechanical Engineering (AREA)
  • Health & Medical Sciences (AREA)
  • Dentistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Packages (AREA)

Abstract

The present invention proposes a kind of novel stem cells storage container, including:Outer courage, liner, first is equipped at the top of outer courage renovates renovated with second, first renovates the one end renovated with second crosses hinge connection with outer Hymecromone, first other end renovated and the second other end slitless connection renovated, arc pressuring plate is equipped at first semicircular indentations renovated, arc pressuring plate also is provided at second semicircular indentations renovated, first arc pressuring plate renovated is butted into cylindric nozzle with the second arc pressuring plate renovated, liner is set in outer courage, the bottleneck of liner is located at the cylindric nozzle of outer courage, and stretch out cylindric nozzle, twist-on has corking on the bottleneck of liner, the bottom of liner is equipped with pallet, the inner wall surrounding of liner is uniformly installed with multiple locating rings, holding groove is correspondingly provided with immediately below each locating ring, holding groove is set on pallet, refrigerant is filled between liner and outer courage.The configuration of the present invention is simple totally, can be stored efficiently.

Description

A kind of novel stem cells storage container
Technical field
The present invention relates to storage container technical field, more particularly to a kind of novel stem cells storage container.
Background technology
Stem cell (Stem cell, SC) is that a kind of pluripotency with self-renewing (self-renewing) ability is thin Born of the same parents, under certain condition, it can be divided into a variety of APSC pluripotent cells, be that one kind has self-replacation and multi-lineage potential Initial cell, i.e. stem cell keeps not orienting differentiation state and with proliferative capacity, suitable condition or give it is suitable Signal, it can be divided into multiple functions cell or tissue organ, and medical field is called " general-purpose cell ", and also someone is popular and shape As ground is called " all right cell of What for ".Source of human stem cell is in embryo, fetal tissue and adult tissue.From embryo and tire The embryonic stem cell of youngster's tissue has pluripotent differentiation characteristic, can be divided into ripe individual more than 200 kinds of almost all or more in vivo Mature cell type.And the adult stem cell (adult stem cell) that group of individuals of growing up knits source has candidate stem cell, god Through stem cell and pancreatic stem cells etc..
After stem cell is isolated and cultured from different tissues, using Testing and appraisal, then frozen In -196 DEG C of profound hypothermia, in order to which stem cell can recover to feed back to patient when clinic needs, reach treatment The purpose of disease.
Therefore the storage of stem cell is then particularly important, and the present invention devises a kind of novel stem cells storage container,
Invention content
In view of the above-mentioned problems, it is an object of the invention to propose a kind of novel stem cells storage container, it is simple in structure, it can Totally, it is efficiently stored.
Technical solution is used by the present invention solves above-mentioned technical problem:A kind of novel stem cells storage container, including: Outer courage, liner, the outer courage are square babinet, open top, are equipped with first at the top of the outer courage and renovate and are renovated with second, Hinge connection is crossed in described first one end renovated with the outer Hymecromone, and hinge is crossed in described second one end renovated with the outer Hymecromone Connection, first other end renovated and the described second other end slitless connection renovated, first other end renovated Center be equipped with semicircular indentations, the center of second other end renovated is equipped with corresponding semicircle lack Mouthful, described first, which renovates the semicircular indentations renovated with second, is butted into a circular hole, first semicircular indentations renovated Place be equipped with arc pressuring plate, the arc pressuring plate with described first renovate it is vertical be fixedly connected, second semicircle renovated Also is provided with arc pressuring plate at v notch v, and with described second renovate it is vertical be fixedly connected, the described first arc connection renovated Plate and the second arc pressuring plate renovated are butted into cylindric nozzle, and the liner is set in the outer courage, and the liner is Ampuliform structure, the bottleneck of liner are located at the cylindric nozzle of the outer courage, and stretch out the cylindric nozzle, the liner Twist-on has corking on bottleneck, and the corking lower end is abutted with the cylindric nozzle upper end, and the bottom of the liner is equipped with support Disk, the pallet are threadedly coupled with the liner, and the pallet is positioned over bottom in the outer courage, wherein, inside the liner Center upper end is equipped with neck tube, and the upper end of the neck tube is fixedly connected with liner bottleneck, and the inner wall surrounding of the liner is uniformly fixed Multiple locating rings are installed, the locating ring is used to carry out guide-localization to carrying cylinder, and the underface of each locating ring corresponds to Equipped with holding groove, the holding groove is set on the pallet, and refrigerant is filled between the liner and the outer courage.
Further, it described first renovates to renovate with second and is respectively equipped with handle, described first renovates and turned over described second Lid is equipped with seal washer with the outer courage junction.
Further, it is installed with idler wheel respectively in the bottom four corners of the outer courage.
Further, it is equipped with sealing shroud before the bottleneck of the liner and the cylindric nozzle of the outer courage.
Further, the refrigerant is liquid nitrogen.
Further, ecto-entad is equipped with heat insulation layer, getter layer successively on the outer courage inner wall, and the getter layer uses Propylene glycol.
The advantage of the invention is that:Locating ring is set on the inner wall of liner, the cylinder edge that carries for storing stem cell positions Circle is placed, and is not only able to be oriented to, is made to carry the surface that cylinder is placed exactly in holding groove, prevents the stem cell fallen from polluting Liner, and fixation can be positioned, it prevents from proposing cylinder shaking;At the top of outer courage, setting first is renovated renovates with second, can beat Taking-up liner is opened, and backs out pallet, clears up the stem cell in holding groove.
Description of the drawings
It, below will be to specific in order to illustrate more clearly of the specific embodiment of the invention or technical solution of the prior art Embodiment or attached drawing needed to be used in the description of the prior art are briefly described, it should be apparent that, in being described below Attached drawing is some embodiments of the present invention, for those of ordinary skill in the art, before not making the creative labor It puts, can also be obtained according to these attached drawings other attached drawings.
Fig. 1 is a kind of perspective structure figure of novel stem cells storage container of the present invention;
Fig. 2 is a kind of structure diagram of the outer courage of novel stem cells memory of the present invention.
Wherein:1st, outer courage;2nd, it first renovates;3rd, it second renovates;4th, hinge;5th, corking;6th, liner;7th, pallet;8th, idler wheel; 9th, neck tube;10th, cylinder is carried;11st, locating ring;12nd, holding groove;13rd, handle;14th, arc pressuring plate.
Specific embodiment
Technical scheme of the present invention is clearly and completely described below in conjunction with attached drawing, it is clear that described implementation Example is part of the embodiment of the present invention, instead of all the embodiments.Based on the embodiments of the present invention, ordinary skill Personnel's all other embodiments obtained without making creative work belong to the model of the utility model protection It encloses.
In the description of the present invention, it should be noted that term " " center ", " on ", " under ", "left", "right", " vertical ", The orientation or position relationship of the instructions such as " level ", " interior ", " outer " be based on orientation shown in the drawings or position relationship, merely to Convenient for the description present invention and simplify description rather than instruction or imply signified device or element must have specific orientation, With specific azimuth configuration and operation, therefore it is not intended that limitation to the utility model.In addition, term " first ", " the Two ", " third " is only used for description purpose, and it is not intended that instruction or hint relative importance.
As depicted in figs. 1 and 2, a kind of novel stem cells storage container, including:Outer courage 1, liner 6, the outer courage 1 is just Cube babinet, open top, 1 top of outer courage, which is equipped with first, renovates 2 and second and renovates 3, and described first renovates 2 one end It being connect with the outer courage 1 by hinge 4, described second one end for renovating 3 is connect with the outer courage 1 by hinge 4, and described One renovate 2 other end and described second renovate 3 other end slitless connection, described first renovates the centre bit of 2 other end Installing semicircular indentations, the described second center for renovating 3 other end is equipped with corresponding semicircular indentations, and described the One, which renovates 2 and second, renovates 3 semicircular indentations and is butted into a circular hole, and described first renovates and be equipped at 2 semicircular indentations Arc pressuring plate 14, the arc pressuring plate 14 with described first renovate 2 it is vertical be fixedly connected, described second renovates 3 semicircle Also is provided with arc pressuring plate 14 at v notch v, and with described second renovate 3 it is vertical be fixedly connected, described first renovates 2 arc Connecting plate 14 and second renovates 3 arc pressuring plate 14 and is butted into cylindric nozzle, and the liner 6 is set in the outer courage 1, The liner 6 is ampuliform structure, and the bottleneck of liner 6 is located at the cylindric nozzle of the outer courage 1, and stretch out the cylindrical pipe Mouthful, twist-on has corking 5 on the bottleneck of the liner 6, and 5 lower end of corking is abutted with the cylindric nozzle upper end, described interior The bottom of courage 6 is equipped with pallet 7, and the pallet 7 is threadedly coupled with the liner 6, and the pallet 7 is positioned in the outer courage 1 Bottom, wherein, the 6 inside center upper end of liner is equipped with neck tube 9, and the upper end of the neck tube 9 is fixedly connected with 6 bottleneck of liner, The inner wall surrounding of the liner 6 is uniformly installed with multiple locating rings 11, and the locating ring 11 is used to lead to carrying cylinder 10 To positioning, the underface of each locating ring 11 is correspondingly provided with holding groove 12, and the holding groove 12 is set on the pallet 7, Refrigerant is filled between the liner 6 and the outer courage 1.
Further, it described first 2 and second are renovated renovates handle 13 is respectively equipped on 3, described first renovates 2 and described Two renovate 3 is equipped with seal washer with outer 1 junction of courage.
Further, it is installed with idler wheel 8 respectively in the bottom four corners of the outer courage 1.
Further, it is equipped with sealing shroud before the bottleneck of the liner 6 and the cylindric nozzle of the outer courage 1.
Further, the refrigerant is liquid nitrogen.
Further, ecto-entad is equipped with heat insulation layer, getter layer successively on 1 inner wall of outer courage, and the getter layer is adopted Use propylene glycol.
Finally it should be noted that:The above embodiments are only used to illustrate the technical solution of the present invention., rather than its limitations;To the greatest extent Pipe is described in detail the present invention with reference to foregoing embodiments, it will be understood by those of ordinary skill in the art that:Its according to Can so modify to the technical solution recorded in foregoing embodiments either to which part or all technical features into Row equivalent replacement;And these modifications or replacement, various embodiments of the present invention technology that it does not separate the essence of the corresponding technical solution The range of scheme.

Claims (6)

1. a kind of novel stem cells storage container, which is characterized in that including:Outer courage, liner, the outer courage are square babinet, Open top is equipped with first at the top of the outer courage and renovates and renovated with second, described first one end renovated and the outer Hymecromone Hinge connection is crossed, hinge connection, first other end renovated and institute are crossed in described second one end renovated with the outer Hymecromone The second other end slitless connection renovated is stated, the center of first other end renovated is equipped with semicircular indentations, described The center of second other end renovated is equipped with corresponding semicircular indentations, and described first renovates the semicircle renovated with second V notch v is butted into a circular hole, and arc pressuring plate, the arc pressuring plate are equipped at first semicircular indentations renovated With described first renovate it is vertical be fixedly connected, also be provided with arc pressuring plate at second semicircular indentations renovated, and with institute It states second and renovates and be vertically fixedly connected, first arc pressuring plate renovated is butted into circle with the second arc pressuring plate renovated Tubular nozzle, the liner are set in the outer courage, and the liner is ampuliform structure, and the bottleneck of liner is located at the outer courage At cylindric nozzle, and the cylindric nozzle is stretched out, twist-on has corking, the corking lower end and institute on the bottleneck of the liner It states cylindric nozzle upper end to abut, the bottom of the liner is equipped with pallet, and the pallet is threadedly coupled with the liner, described Pallet is positioned over bottom in the outer courage, wherein, the liner inside center upper end be equipped with neck tube, the upper end of the neck tube with it is interior Vase mouth is fixedly connected, and the inner wall surrounding of the liner is uniformly installed with multiple locating rings, and the locating ring is used for carrying Cylinder carries out guide-localization, and holding groove is correspondingly provided with immediately below each locating ring, and the holding groove is set on the pallet, Refrigerant is filled between the liner and the outer courage.
2. a kind of novel stem cells storage container according to claim 1, which is characterized in that described first renovates and second Renovate and be respectively equipped with handle, described first renovate with described second renovate with the outer courage junction be equipped with seal washer.
A kind of 3. novel stem cells storage container according to claim 1, which is characterized in that the bottom four corners of the outer courage It is upper to be installed with idler wheel respectively.
4. a kind of novel stem cells storage container according to claim 1, which is characterized in that the bottleneck of the liner and institute Sealing shroud is equipped with before stating the cylindric nozzle of outer courage.
5. a kind of novel stem cells storage container according to claim 1, which is characterized in that the refrigerant is liquid Nitrogen.
6. a kind of novel stem cells storage container according to claim 1, which is characterized in that by outer on the outer courage inner wall It is inwardly equipped with heat insulation layer, getter layer successively, the getter layer uses propylene glycol.
CN201711480810.1A 2017-12-29 2017-12-29 A kind of novel stem cells storage container Pending CN108207932A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201711480810.1A CN108207932A (en) 2017-12-29 2017-12-29 A kind of novel stem cells storage container

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201711480810.1A CN108207932A (en) 2017-12-29 2017-12-29 A kind of novel stem cells storage container

Publications (1)

Publication Number Publication Date
CN108207932A true CN108207932A (en) 2018-06-29

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Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6119465A (en) * 1999-02-10 2000-09-19 Mullens; Patrick L. Shipping container for storing materials at cryogenic temperatures
CN203958956U (en) * 2014-05-28 2014-11-26 成都盛杰低温设备有限公司 The suspended type pallet rotary system of liquid nitrogen biological container
CN204560763U (en) * 2015-04-13 2015-08-19 湖南省生宝生物科技有限公司 Cord blood stem cell holding vessel
CN204560761U (en) * 2015-04-08 2015-08-19 泰州市疾病预防控制中心 A kind of liquid nitrogen cell or biological sample cryopreservation device
CN205865771U (en) * 2016-05-27 2017-01-11 沈阳航天新光低温容器制造有限责任公司 500 liters of holding vessels of medical stem cell
CN106939964A (en) * 2017-03-04 2017-07-11 杭州医学院 A kind of thermos bottle type liquid nitrogen container and inner bag replacement method
CN206641292U (en) * 2017-04-14 2017-11-17 青岛瑞思德生物科技有限公司 A kind of cell liquid nitrogen storage device

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6119465A (en) * 1999-02-10 2000-09-19 Mullens; Patrick L. Shipping container for storing materials at cryogenic temperatures
CN203958956U (en) * 2014-05-28 2014-11-26 成都盛杰低温设备有限公司 The suspended type pallet rotary system of liquid nitrogen biological container
CN204560761U (en) * 2015-04-08 2015-08-19 泰州市疾病预防控制中心 A kind of liquid nitrogen cell or biological sample cryopreservation device
CN204560763U (en) * 2015-04-13 2015-08-19 湖南省生宝生物科技有限公司 Cord blood stem cell holding vessel
CN205865771U (en) * 2016-05-27 2017-01-11 沈阳航天新光低温容器制造有限责任公司 500 liters of holding vessels of medical stem cell
CN106939964A (en) * 2017-03-04 2017-07-11 杭州医学院 A kind of thermos bottle type liquid nitrogen container and inner bag replacement method
CN206641292U (en) * 2017-04-14 2017-11-17 青岛瑞思德生物科技有限公司 A kind of cell liquid nitrogen storage device

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
权凯 等: "《牛羊人工授精技术图解》", 31 December 2009, 金盾出版社 *

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Application publication date: 20180629