CN108186983B - Plaster for treating rheumatoid bone diseases and preparation method thereof - Google Patents

Plaster for treating rheumatoid bone diseases and preparation method thereof Download PDF

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CN108186983B
CN108186983B CN201810093895.6A CN201810093895A CN108186983B CN 108186983 B CN108186983 B CN 108186983B CN 201810093895 A CN201810093895 A CN 201810093895A CN 108186983 B CN108186983 B CN 108186983B
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plaster
bone diseases
fine powder
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CN108186983A (en
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麻礽聪
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232—Angelica
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/63—Arthropods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/21—Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/236—Ligusticum (licorice-root)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/26—Aristolochiaceae (Birthwort family), e.g. heartleaf
    • A61K36/268—Asarum (wild ginger)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/286—Carthamus (distaff thistle)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/32—Burseraceae (Frankincense family)
    • A61K36/324—Boswellia, e.g. frankincense
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/32—Burseraceae (Frankincense family)
    • A61K36/328—Commiphora, e.g. mecca myrrh or balm of Gilead
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/54—Lauraceae (Laurel family), e.g. cinnamon or sassafras
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/56—Loganiaceae (Logania family), e.g. trumpetflower or pinkroot
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/708—Rheum (rhubarb)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/714—Aconitum (monkshood)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/716—Clematis (leather flower)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/888—Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
    • A61K36/8884—Arisaema, e.g. Jack in the pulpit
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/888—Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
    • A61K36/8888—Pinellia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8966—Fritillaria, e.g. checker lily or mission bells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/898—Orchidaceae (Orchid family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/906—Zingiberaceae (Ginger family)
    • A61K36/9066—Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms

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Abstract

The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a plaster for treating rheumatic bone diseases and a preparation method thereof, wherein the plaster is prepared from the following raw materials in parts by weight: the traditional Chinese medicine composition is prepared by combining multiple Chinese herbal medicines, comprehensively applying treatment, wherein the effective components of the medicine penetrate into a focus through skin, improving blood circulation of a lesion part, promoting regression of local inflammatory edema, and relieving muscle tension and spasm, so that the traditional Chinese medicine composition is suitable for rapidly relieving symptoms, and is suitable for various rheumatic bone diseases such as rheumatism, rheumatoid arthritis, degenerative arthritis and the like. The medicine components have low price and are suitable for industrial production.

Description

Plaster for treating rheumatoid bone diseases and preparation method thereof
Technical Field
The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a plaster for treating rheumatic bone diseases and a preparation method thereof.
Background
Common rheumatic bone diseases include rheumatism, rheumatoid arthritis, degenerative arthritis, ankylosing spondylitis, cervical spondylosis, lumbar spondylosis, scapulohumeral periarthritis, hyperosteogeny, femoral head necrosis, fracture, joint dislocation, soft tissue injury, etc. For the treatment of the diseases, western medicines are mainly used for pain relief, operation and the like, although the curative effect is quick, the side effect and the operation injury are large, the cost is high, and the influence on the liver, the kidney and the gastrointestinal tract is large after the western medicines are taken for a long time. The traditional Chinese medicine ointment is externally used, has the effects of promoting blood circulation to remove blood stasis, dispelling wind and removing arthralgia, reuniting bones and curing injuries, reducing swelling and relieving pain and the like, is convenient to use, low in price, light in side effect of the whole body, small in influence on the liver and the kidney, free of stimulation of the gastrointestinal tract, good in acceptability, and quick in effect and exact in curative effect when the medicine acts on the local part through transdermal absorption.
Disclosure of Invention
The invention aims to solve the defects of the technical problems and provide the plaster for treating the rheumatoid bone diseases, which has the advantages of quick response, good effect, low price, convenient use and no obvious side effect.
The second purpose of the invention is to provide a preparation method of the plaster for treating the rheumatoid bone disease, which has simple preparation process.
In order to achieve the above purpose, the technical scheme of the invention is as follows:
a plaster for treating rheumatism bone disease is prepared from the following raw materials in parts by weight: 3 parts of angelica, 3 parts of ligusticum wallichii, 3 parts of frankincense, 3 parts of myrrh, 2 parts of cassia twig, 2 parts of safflower, 2 parts of ground beetle, 2 parts of radix clematidis, 2 parts of sappan wood, 3 parts of achyranthes, 2 parts of asarum, 2 parts of prepared kusnezoff monkshood root, 2 parts of prepared monkshood, 2 parts of prepared arisaema, 2 parts of prepared pinellia ternate, 3 parts of rheum officinale, 3 parts of bletilla striata, 2 parts of thunberg fritillary bulb, 2 parts of radix angelicae, 2 parts of nux vomica, 3 parts of turmeric and 10 parts.
The invention also provides a preparation method of the plaster for treating the rheumatism bone disease, which is characterized by comprising the following steps:
s1: uniformly mixing various components except the borneol sesame oil in the formula, crushing at normal temperature, and sieving with a 100-mesh sieve to obtain fine powder for later use;
s2: separately pulverizing Borneolum Syntheticum in the composition into fine powder;
s3: adding the sesame oil in parts by mass, and decocting into paste;
s4: adding the fine powder obtained in the step S1 into melted sesame oil, and stirring uniformly, and adding the fine powder of borneol obtained in the step S2 when the temperature is reduced to 70 ℃, and stirring uniformly;
s5: the plaster prepared by the steps is evenly spread on special cloth or other substrates of various specifications, and the plaster for treating the rheumatoid bone diseases is prepared.
The invention has the following beneficial effects:
the invention adopts a plurality of Chinese herbal medicines to jointly act and comprehensively treat, the effective components of the medicine permeate into focus through skin, improve the blood circulation of the lesion part, promote the regression of local inflammatory edema and relieve muscle tension and spasm, thereby rapidly relieving symptoms, and the medicine is suitable for various rheumatic bone diseases such as rheumatism, rheumatoid arthritis, degenerative arthritis, ankylosing spondylitis, cervical spondylosis, lumbar spondylosis, scapulohumeral periarthritis, hyperosteogeny, femoral head necrosis, fracture, dislocation of joints, soft tissue injury and the like. The medicine components have low price and are suitable for industrial production.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention clearer, the technical solutions in the embodiments of the present invention are clearly and completely described below, and it is obvious that the described embodiments are a part of the embodiments of the present invention, but not all of the embodiments. Thus, the following detailed description of the embodiments of the present invention is not intended to limit the scope of the invention as claimed, but is merely representative of selected embodiments of the invention. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
The present invention will be further illustrated by the following specific examples.
Example 1
Plaster for treating rheumatoid bone diseases
The invention provides a plaster for treating osteopathy, which comprises the following components in parts by weight: 3 parts of angelica, 3 parts of ligusticum wallichii, 3 parts of frankincense, 3 parts of myrrh, 2 parts of cassia twig, 2 parts of safflower, 2 parts of ground beetle, 2 parts of radix clematidis, 2 parts of sappan wood, 3 parts of achyranthes, 2 parts of asarum, 2 parts of prepared kusnezoff monkshood root, 2 parts of prepared monkshood, 2 parts of prepared arisaema, 2 parts of prepared pinellia ternate, 3 parts of rheum officinale, 3 parts of bletilla striata, 2 parts of thunberg fritillary bulb, 2 parts of radix angelicae, 2 parts of nux vomica, 3 parts of turmeric, 10.
The preparation method of the plaster for treating the rheumatoid bone disease provided by the invention comprises the following steps:
s1: mixing the Chinese herbal medicines except Borneolum Syntheticum, pulverizing at room temperature, sieving with 200 mesh sieve, and making into fine powder;
s2: separately pulverizing Borneolum Syntheticum in the composition into fine powder;
s3: 500 parts of balm, and melting at 120 ℃;
s4: adding the fine powder obtained in the step S1 into melted balm, stirring, and adding the fine powder of borneol obtained in the step S2 when the temperature is reduced to 70 ℃, and stirring uniformly;
s5: the plaster prepared by the steps is evenly coated on special cloth or other substrates with various specifications to obtain the plaster for treating the rheumatoid bone diseases.
Example 2
The clinical effects of the agent for treating bone diseases according to the present invention will be further described below by taking only a few typical cases.
Yang women, 28 years old, shop salers suffer from lumbar muscle strain, supraspinal ligament strain and impaired lumbar activity due to long-term sitting and standing. When the plaster is used for external application for 2 times, the waist pain disappears, and the waist moves freely.
Mr. Dai, 72 years old, suffered from knee joint hyperosteogeny, knee joint swelling, pain, and difficulty in movement for many years. The ointment of the invention takes effect for the first time, and the pain and swelling of the knee joint are reduced. After the ointment is continuously used for 3 times, knee joint symptoms are obviously improved, pain and swelling disappear, and joint movement is obviously improved.
The plum female, aged 40 years, suffered from lumbar intervertebral disc protrusion for 3 years, suffered from lumbago and pain of lower limbs, numbness, and difficulty in walking when sitting and standing, the pain is relieved for the first time by using the ointment of the invention, and the plum female is basically recovered for 5 times by using the ointment of the invention.
Mr. Ke, 66 years old, straight lower radius fracture, after using the ointment of the invention for 4 courses of treatment, the fracture has healed, the function of the affected limb is basically recovered.
Mr. Zhang, 53 years old, suffered from gouty arthritis for years, repeatedly suffered from attack, ankle joint swelling and severe pain, and can not walk, and after using the plaster of the invention for 3 times, the plaster is basically cured.
The above disclosure is only for the purpose of illustrating the preferred embodiments of the present invention, and it is therefore to be understood that the invention is not limited by the scope of the appended claims.

Claims (2)

1. A plaster for treating rheumatism bone diseases is characterized by being prepared from the following raw materials in parts by weight: 3 parts of angelica, 3 parts of ligusticum wallichii, 3 parts of frankincense, 3 parts of myrrh, 2 parts of cassia twig, 2 parts of safflower, 2 parts of ground beetle, 2 parts of radix clematidis, 2 parts of sappan wood, 3 parts of achyranthes, 2 parts of asarum, 2 parts of prepared kusnezoff monkshood root, 2 parts of prepared monkshood, 2 parts of prepared arisaema, 2 parts of prepared pinellia ternate, 3 parts of rheum officinale, 3 parts of bletilla striata, 2 parts of thunberg fritillary bulb, 2 parts of radix angelicae, 2 parts of nux vomica, 3 parts of turmeric and 500.
2. A method for preparing a plaster for treating rheumatoid bone disease according to claim 1, which comprises the steps of:
s1: uniformly mixing various components except the borneol sesame oil in the formula, crushing at normal temperature, and sieving with a 100-mesh sieve to obtain fine powder for later use;
s2: separately pulverizing Borneolum Syntheticum in the composition into fine powder;
s3: 500 parts of balm, and melting at 120 ℃;
s4: adding the fine powder obtained in the step S1 into melted balm, stirring, and adding the fine powder of borneol obtained in the step S2 when the temperature is reduced to 70 ℃, and stirring uniformly;
s5: the plaster prepared by the steps is evenly spread on special cloth or other substrates of various specifications, and the plaster for treating the rheumatoid bone diseases is prepared.
CN201810093895.6A 2018-01-31 2018-01-31 Plaster for treating rheumatoid bone diseases and preparation method thereof Active CN108186983B (en)

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CN112089779A (en) * 2020-11-12 2020-12-18 赵艳霞 Plaster for treating wind-cold-dampness pain

Citations (1)

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Publication number Priority date Publication date Assignee Title
CN102697899A (en) * 2012-05-24 2012-10-03 侯俊 Traditional Chinese medicine composition for treating osteoarthritis and preparation method thereof

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102697899A (en) * 2012-05-24 2012-10-03 侯俊 Traditional Chinese medicine composition for treating osteoarthritis and preparation method thereof

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* Cited by examiner, † Cited by third party
Title
综合治疗膝关节增生性关节炎体会;甄志刚等;《中医正骨》;19971220;第9卷(第06期);第26页 *

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