CN108183383A - A kind of excimer laser applied to therapy of vitiligo - Google Patents

A kind of excimer laser applied to therapy of vitiligo Download PDF

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Publication number
CN108183383A
CN108183383A CN201810058011.3A CN201810058011A CN108183383A CN 108183383 A CN108183383 A CN 108183383A CN 201810058011 A CN201810058011 A CN 201810058011A CN 108183383 A CN108183383 A CN 108183383A
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CN
China
Prior art keywords
cavity
therapy
excimer laser
vitiligo
electrode
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Granted
Application number
CN201810058011.3A
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Chinese (zh)
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CN108183383B (en
Inventor
梁勖
方晓东
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Anhui ouwu Technology Co.,Ltd.
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Hefei Institutes of Physical Science of CAS
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    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01SDEVICES USING THE PROCESS OF LIGHT AMPLIFICATION BY STIMULATED EMISSION OF RADIATION [LASER] TO AMPLIFY OR GENERATE LIGHT; DEVICES USING STIMULATED EMISSION OF ELECTROMAGNETIC RADIATION IN WAVE RANGES OTHER THAN OPTICAL
    • H01S3/00Lasers, i.e. devices using stimulated emission of electromagnetic radiation in the infrared, visible or ultraviolet wave range
    • H01S3/02Constructional details
    • H01S3/03Constructional details of gas laser discharge tubes
    • H01S3/036Means for obtaining or maintaining the desired gas pressure within the tube, e.g. by gettering, replenishing; Means for circulating the gas, e.g. for equalising the pressure within the tube
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01SDEVICES USING THE PROCESS OF LIGHT AMPLIFICATION BY STIMULATED EMISSION OF RADIATION [LASER] TO AMPLIFY OR GENERATE LIGHT; DEVICES USING STIMULATED EMISSION OF ELECTROMAGNETIC RADIATION IN WAVE RANGES OTHER THAN OPTICAL
    • H01S3/00Lasers, i.e. devices using stimulated emission of electromagnetic radiation in the infrared, visible or ultraviolet wave range
    • H01S3/02Constructional details
    • H01S3/03Constructional details of gas laser discharge tubes
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01SDEVICES USING THE PROCESS OF LIGHT AMPLIFICATION BY STIMULATED EMISSION OF RADIATION [LASER] TO AMPLIFY OR GENERATE LIGHT; DEVICES USING STIMULATED EMISSION OF ELECTROMAGNETIC RADIATION IN WAVE RANGES OTHER THAN OPTICAL
    • H01S3/00Lasers, i.e. devices using stimulated emission of electromagnetic radiation in the infrared, visible or ultraviolet wave range
    • H01S3/02Constructional details
    • H01S3/03Constructional details of gas laser discharge tubes
    • H01S3/038Electrodes, e.g. special shape, configuration or composition

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  • Physics & Mathematics (AREA)
  • Electromagnetism (AREA)
  • Engineering & Computer Science (AREA)
  • Plasma & Fusion (AREA)
  • Optics & Photonics (AREA)
  • Lasers (AREA)

Abstract

The invention discloses a kind of excimer lasers applied to therapy of vitiligo, electrode is installed in the inside of cavity, preionization part is separately installed in the left and right sides of electrode, conductive column is installed at the top of cavity, described conductive column one end is connected with high voltage pulse generation module, the cathode of other end connection electrode, on the end cap at the left and right end of cavity disresonance window is had at the position of face electrode, diaphragm is separately installed at both ends disresonance window, two non-parallel installations of diaphragm, at inside of cavity or so end, end cap inner wall is separately installed with motor, both ends motor is synchronized with the movement, drive external coupler rotation, external coupler drives intercoupler to rotate by magnetic coupling, intercoupler drives circulating fan high-speed rotation by axis.The present invention preferably can be applied to Gao Zhongying therapy of vitiligo demand and be more suitable for the modular requirement of medical product application, and manufacturing cost and use cost is low, convenient for safeguarding and repairing.

Description

A kind of excimer laser applied to therapy of vitiligo
Technical field
The present invention relates to medical apparatus technical field more particularly to a kind of excimer laser applied to therapy of vitiligo Device.
Background technology
Leucoderma is one of a kind of idiopathic skin pigment depigmentation disease, three big chronic disease of world's skin disease, the trouble of crowd Sick rate about 1~2%, China is there are about 20,000,000 populations with leucoderma.Its skin lesion directly affects patient's appearance, particular on The skin lesion of exposure portion brings serious psychological pressure to patient, and patient is made to feel that distress, anxiety, setback, self-confidence decline, from And influence the quality of life of patient
Traditional therapy of vitiligo method mainly have epidermic grafting and melanocyte transplanting based on surgical operation therapy, with hormone With immunosuppressor based on drug therapy, with long wave ultraviolet (ultraviolet A UVA) and ultraviolet B radiation Phototherapy or photochemotherapy based on (ultraviolet B UVB) etc., but due to curative effect, safety, convenience etc., It is not very satisfied.
308 nm excimer laser therapy of vitiligo are a kind of novel therapies to come into vogue in recent years, its profit With the uv excimer laser of 308 nanometers of wavelength to affected skin direct irradiation, promote activated T lymphocytes growth, so as to lead Melanocyte in leucoderma affected skin is caused to restore, reaches therapeutic effect.There is this method quick, treatment to facilitate, use peace Congruent feature.
Existing excimer laser periodic maintenance cleaning and replacement in due course are inconvenient, and are unsuitable for Gao Zhongying operation and length Time runs.
Invention content
The defects of the object of the invention is exactly to make up prior art, provides a kind of quasi-molecule applied to therapy of vitiligo Laser.
The present invention is achieved by the following technical solutions:
A kind of excimer laser applied to therapy of vitiligo, includes cavity, and cavity both ends are respectively equipped with end cap, in cavity Portion is equipped with electrode, in the left and right of electrode filled with the working gas that can generate 308 nm excimer lasers in the inside of cavity Side is separately installed with preionization part, and conductive column is equipped at the top of cavity, and described conductive column one end is connected with pulse height Generation module is pressed, the cathode of other end connection electrode is opened respectively on the end cap at the left and right end of cavity at the position of face electrode There is disresonance window, diaphragm, two non-parallel installations of diaphragm, in cavity are separately installed at both ends disresonance window Internal left and right end end cap inner wall is separately installed with motor, external coupler is separately installed on the output shaft of two motors, two The side of a external coupler is separately installed with intercoupler, and circulating fan is equipped with by axis between two intercouplers, and two End motor is synchronized with the movement, and drives external coupler rotation, and external coupler drives intercoupler to rotate by magnetic coupling, intercoupler Circulating fan high-speed rotation is driven by axis.
The ceramics that the preionization part includes solid metal grounding rod and is sleeved on outside solid metal grounding rod The cathode of pipe, the solid metal grounding rod and electrode connects.
The top of the cavity is ceramic wafer, and the conductive column is mounted on ceramic wafer.
The ceramic wafer is fixed on cavity by ceramic wafer briquetting.
Multiple wind deflectors are installed in the inside of cavity.
Isolation cover is covered with outside motor and external coupler.
The axis is mounted on bearings, and bearing is externally connected with support element, and the support element is fixedly mounted in the cavity Wall.
Sealing ring is equipped between diaphragm and end cap.
1)Filled with the working gas that can generate 308 nm excimer lasers inside laser cavity, pressure reaches several big Air pressure;
2)Both ends motor is synchronized with the movement under the action of signal is controlled, and drives external coupler rotation;External coupler passes through magnetic force coupling Crossed belt moves intercoupler rotation, and intercoupler drives circulating fan high-speed rotation by axis;Circulating fan on axis by installing Bearing and then connection support element are fixed on cavity.In this way, under circulating fan high-speed rotation, pass through wind deflector shape in laser cavity Into the airflow circulating of specific wind path;
3)Conductive column conducts the high-voltage pulse that the high voltage pulse generation module that top connects generates to cathode;Then cathode first with Corona discharge occurs for the ground connection preionization stick of ceramic tube isolation, forms the preionization of laser gas;Subsequent cathode and the sun of ground connection Interpolar forms main discharge, activates two interelectrode gases, generates 308 nm excimer lasers;
4)The laser of generation forms shaking for laser by the window at both ends between the two pieces of resonant cavity sheets installed outside laser cavity Swing amplification, final output;
5)The air-flow of high-speed circulating causes interelectrode gas to update in laser cavity, waits for the arrival of next pulse high pressure And energized gas light extraction.
It is an advantage of the invention that:The present invention includes more the preionization structure of clean and effective, interior-type both-end magnetic coupling and drives Dynamic circulating air duct design and disresonance window design, can preferably be applied to Gao Zhongying therapy of vitiligo demand, Yi Jigeng Add the modular requirement for being suitable for medical product application, manufacturing cost and use cost is low, convenient for safeguarding and repairing.
Description of the drawings
Fig. 1 is the side view of the present invention.
Fig. 2 is the front view of the present invention.
Fig. 3 is the preionization part-structure figure of the present invention.
Fig. 4 is the circulating air duct part-structure figure of the present invention.
Fig. 5 is window portion structure chart of the present invention.
Specific embodiment
As shown in Figure 1, 2, a kind of excimer laser applied to therapy of vitiligo includes cavity 1,1 both ends of cavity End cap 2 is respectively equipped with, filled with the working gas that can generate 308 nm excimer lasers inside cavity 1, in the inside of cavity 1 Electrode 3 is installed, preionization part 13 is separately installed in the left and right sides of electrode 3, conductive column 4 is installed at the top of cavity 1, Described 4 one end of conductive column is connected with high voltage pulse generation module 5, the cathode 6 of other end connection electrode 3, in the left and right of cavity 1 Disresonance window 7 is had at the position of face electrode 3 on the end cap 2 at end, is separately installed at both ends disresonance window 7 Diaphragm 8, two 8 non-parallel installations of diaphragm, inside of cavity 1 or so end, 2 inner wall of end cap is separately installed with motor 9, External coupler 10 is separately installed on the output shaft of two motors 9, interior coupling is separately installed in the side of two external couplers 10 Clutch 11 is equipped with circulating fan 12 between two intercouplers 11 by axis, and both ends motor 9 is synchronized with the movement, and drives outer coupling Clutch 10 rotates, and external coupler 10 drives intercoupler 11 to rotate by magnetic coupling, and intercoupler 11 is driven by axis and recycled 12 high-speed rotation of wind turbine.
It is connect as shown in figure 3, the preionization part 13 includes solid metal grounding rod 14 and is sleeved on solid metal The ceramic tube 15 of 14 outside of ground stick, the solid metal grounding rod 14 are connect with the cathode 6 of electrode 3.
The top of the cavity 1 is ceramic wafer 16, and the conductive column 4 is mounted on ceramic wafer 16.
The ceramic wafer 16 is fixed on cavity 1 by ceramic wafer briquetting 17.
Multiple wind deflectors 18 are installed in the inside of cavity 1.
Isolation cover 19 is covered in the outside of motor 9 and external coupler 10.
The axis is mounted on bearing 20, and bearing 20 is externally connected with support element 21, and the support element 21 is fixedly mounted In 1 inner wall of cavity.
Sealing ring 22 is equipped between diaphragm 8 and end cap 2.
1)Preionization part is as shown in figure 3, using 14 housing ceramic tube of solid metal grounding rod, 15 structure.Different from common Spark preionization mode, more efficient and cleaning are suitable for the operation of laser Gao Zhongying and long-play, adapt to medical product Using;
2)As shown in figure 4, being worked asynchronously first using both-end motor, can reduce the power of single motor needs for circulating air duct part It asks;Secondly using interior-type magnetic coupling arrangement, motor and external coupler 10 are integrally sunk in the case where isolation cover is isolated sharp Light inside cavity so that laser cavity is disassembled and installed without outer projecting device convenient for the integral moduleization of laser cavity.
3)Window portion is as shown in figure 5, using non-resonant window design, two pieces of non-parallel installations of diaphragm only serve The effect of thang-kng and confining gas;And laserresonator piece is external, facilitates the design of optical system first, it may be convenient to use Average resonator or unsteady cavity structure;Secondly because, it is fixed to there are needs in consumptive material of the resonant cavity sheet as cavity in medical applications The problem of phase safeguards cleaning and replaces in due course, which adds the design of external resonant cavity sheet, can facilitate later stage resonator The work such as maintenance, the replacement of piece.

Claims (8)

1. a kind of excimer laser applied to therapy of vitiligo, it is characterised in that:Include cavity, cavity both ends are set respectively There is end cap, inside cavity is equipped with electricity filled with the working gas that can generate 308 nm excimer lasers in the inside of cavity Pole is separately installed with preionization part in the left and right sides of electrode, and conductive column, the conductive column one are equipped at the top of cavity End is connected with high voltage pulse generation module, the cathode of other end connection electrode, the face electrode on the end cap at the left and right end of cavity Position at have disresonance window, diaphragm is separately installed at both ends disresonance window, two diaphragms are non-flat Row installation, inside of cavity or so end, end cap inner wall is separately installed with motor, is installed respectively on the output shaft of two motors There is external coupler, be separately installed with intercoupler in the side of two external couplers, pacified between two intercouplers by axis Equipped with circulating fan, both ends motor is synchronized with the movement, and drives external coupler rotation, and external coupler drives interior couple by magnetic coupling Device rotates, and intercoupler drives circulating fan high-speed rotation by axis.
2. a kind of excimer laser applied to therapy of vitiligo according to claim 1, it is characterised in that:Described The ceramic tube that preionization part includes solid metal grounding rod and is sleeved on outside solid metal grounding rod, the solid gold The cathode for belonging to grounding rod and electrode connects.
3. a kind of excimer laser applied to therapy of vitiligo according to claim 1, it is characterised in that:Described The top of cavity is ceramic wafer, and the conductive column is mounted on ceramic wafer.
4. a kind of excimer laser applied to therapy of vitiligo according to claim 3, it is characterised in that:Described Ceramic wafer is fixed on cavity by ceramic wafer briquetting.
5. a kind of excimer laser applied to therapy of vitiligo according to claim 1, it is characterised in that:In cavity Inside multiple wind deflectors are installed.
6. a kind of excimer laser applied to therapy of vitiligo according to claim 1, it is characterised in that:In motor With isolation cover is covered with outside external coupler.
7. a kind of excimer laser applied to therapy of vitiligo according to claim 1, it is characterised in that:Described Axis is mounted on bearings, and bearing is externally connected with support element, and the support element is fixedly mounted on cavity inner wall.
8. a kind of excimer laser applied to therapy of vitiligo according to claim 1, it is characterised in that:In window Sealing ring is equipped between piece and end cap.
CN201810058011.3A 2018-01-22 2018-01-22 Excimer laser applied to vitiligo treatment Active CN108183383B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201810058011.3A CN108183383B (en) 2018-01-22 2018-01-22 Excimer laser applied to vitiligo treatment

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201810058011.3A CN108183383B (en) 2018-01-22 2018-01-22 Excimer laser applied to vitiligo treatment

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CN108183383A true CN108183383A (en) 2018-06-19
CN108183383B CN108183383B (en) 2020-03-17

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020122450A1 (en) * 2001-03-02 2002-09-05 Sparrow Robert W. High repetition rate UV excimer laser
CN101635427A (en) * 2009-05-21 2010-01-27 中国科学院长春光学精密机械与物理研究所 Magnetic coupling hollow-shaft combined cross flow fan in vacuum optical resonant cavity
CN102810810A (en) * 2012-03-02 2012-12-05 中国科学院光电研究院 Single-cavity dual-electrode discharging cavity and quasimolecule laser

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020122450A1 (en) * 2001-03-02 2002-09-05 Sparrow Robert W. High repetition rate UV excimer laser
CN1524323A (en) * 2001-03-02 2004-08-25 �����ɷ� High repetition rate excimer laser system
CN101635427A (en) * 2009-05-21 2010-01-27 中国科学院长春光学精密机械与物理研究所 Magnetic coupling hollow-shaft combined cross flow fan in vacuum optical resonant cavity
CN102810810A (en) * 2012-03-02 2012-12-05 中国科学院光电研究院 Single-cavity dual-electrode discharging cavity and quasimolecule laser

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Effective date of registration: 20210812

Address after: 230088 no.4899, Wangjiang West Road, high tech Zone, Hefei City, Anhui Province

Patentee after: Anhui ouwu Technology Co.,Ltd.

Address before: 230031 Shushan Lake Road, Shushan District, Hefei, Anhui 350

Patentee before: HEFEI INSTITUTES OF PHYSICAL SCIENCE, CAS

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