CN108159429B - Water-soluble rosemary antioxidant and preparation method thereof - Google Patents
Water-soluble rosemary antioxidant and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a water-soluble rosemary antioxidant, which comprises a powdery rosemary fat-soluble antioxidant, Tween 80, polyglycerol fatty acid ester and monoglyceride, wherein the mass ratio of the powdery rosemary fat-soluble antioxidant to the Tween 80 to the polyglycerol fatty acid ester to the monoglyceride is (1-5): (2-5):(0.1-0.5):(0.1-0.5). Meanwhile, the invention also provides a preparation method of the water-soluble rosemary antioxidant. The water-soluble rosemary antioxidant provided by the invention is in a flowing liquid state, is stable in state, does not delaminate or precipitate after being placed for a long time, can be uniformly dispersed in water, and has a very good water-dissolving effect. Meanwhile, the preparation method is simple, low in cost and applicable to large-scale production and application.
Description
Technical Field
The invention belongs to the technical field of chemical industry, and particularly relates to a water-soluble rosemary antioxidant and a preparation method thereof.
Background
Rosemary, which is evergreen shrub of Labiatae, aromatic plant, is cultivated in the region of the original midsea along the coast, is widely cultivated all over the world, and is also cultivated in partial provinces in the southwest of China, wherein the main cultivation areas are Guizhou, Xinjiang, Yunnan, Hunan and Hainan. The main substances such as rosemary essential oil, carnosic acid, carnosol, rosmarinic acid and the like can be extracted from the leaves of rosemary, wherein the rosemary essential oil is used as essence to be applied to daily chemical industries such as spice, air freshener, ant repellent, sterilization, disinsection and the like; carnosic acid, carnosol and rosmarinic acid are used as high-quality natural antioxidants and widely applied to the preservation and quality guarantee of medicines, fried foods, oil-rich foods and various oils and fats.
Rosmarinic acid is highly polar and readily soluble in water, while carnosic acid and carnosol are less polar, poorly soluble in water, readily soluble in low polar solvents, and poorly soluble in edible oils. The commercial rosemary extract products are mainly divided into rosemary essential oil, rosemary oil-soluble antioxidants (the content of rosmarinic acid is taken as the product specification), and rosemary fat-soluble antioxidants (the content of carnosic acid and carnosol is taken as the product specification). Because the content of the rosemary fat-soluble antioxidant in the active ingredients of the rosemary is the maximum, and the antioxidant effect of the rosemary fat-soluble antioxidant is the strongest of the active ingredients, the rosemary fat-soluble antioxidant is the mainstream rosemary antioxidant in the market, the product state of the rosemary fat-soluble antioxidant is solid powder and oily liquid, the rosemary fat-soluble antioxidant is a primary extract of the rosemary fat-soluble antioxidant, the content of the carnosic acid can be controlled to be 5-99%, and the rosemary fat-soluble antioxidant is insoluble in water and also insoluble in edible oil; the latter is solid powdered liposoluble rosemary extract, which is obtained by dissolving the effective components in edible oil through a series of treatments, and is insoluble in water and soluble in edible oil. At present, no rosemary fat-soluble antioxidant product which can be dissolved in water exists in the market, which greatly limits the application range of the rosemary extract as an antioxidant, and therefore, the development of the rosemary fat-soluble antioxidant which can be dissolved in water is very necessary.
Disclosure of Invention
Based on the above, the invention aims to overcome the defects of the prior art and provide the water-soluble rosemary antioxidant which is simple in preparation method and very good in water-dissolving effect.
In order to achieve the purpose, the invention adopts the technical scheme that: a water-soluble rosemary antioxidant comprises a powdery rosemary fat-soluble antioxidant, Tween 80, polyglycerol fatty acid ester and monoglyceride, wherein the mass ratio of the powdery rosemary fat-soluble antioxidant to the powdery rosemary fatty acid ester to the powdery rosemary monoglyceride is (1-5): (2-5): (0.1-0.5): (0.1-0.5).
Preferably, the mass ratio of the powdery rosemary liposoluble antioxidant to the Tween 80 to the polyglycerol fatty acid ester to the monoglyceride is 2: 4: 0.3: 0.2.
preferably, the mass ratio of the powdery rosemary liposoluble antioxidant to the Tween 80 to the polyglycerol fatty acid ester to the monoglyceride is 4: 3: 0.2: 0.3.
preferably, the mass ratio of the powdery rosemary liposoluble antioxidant to the Tween 80 to the polyglycerol fatty acid ester to the monoglyceride is 1: 4: 0.4: 0.4.
the powdery rosemary fat-soluble antioxidant is a commercial product and can be directly obtained by purchase, for example, directly purchased from Wuling sunshine biological technology company limited in Luxi county or Hainan Shupu biological technology company limited.
The invention also aims to provide a preparation method of the water-soluble rosemary antioxidant.
In order to achieve the purpose, the invention adopts the technical scheme that: a method for preparing water-soluble rosemary antioxidant comprises the following steps: weighing the powdery rosemary fat-soluble antioxidant, the Tween 80, the polyglycerol fatty acid ester and the monoglyceride according to the proportion, stirring at the constant temperature of 50-70 ℃ for 20-40 min, and cooling to obtain the rosemary fat-soluble antioxidant.
Preferably, the rosemary lipid-soluble antioxidant, tween 80, polyglycerol fatty acid ester and monoglyceride in powder form are stirred at a constant temperature of 60 ℃ for 30min, and then cooled to obtain the rosemary lipid-soluble antioxidant.
The water-soluble rosemary antioxidant provided by the invention can be used in the fields of medicines, foods and cosmetics.
Compared with the prior art, the invention has the beneficial effects that: (1) the water-soluble rosemary antioxidant provided by the invention has a very good water-dissolving effect, so that the rosemary extract plays an anti-oxidation role in an aqueous solution, and the market range of the rosemary extract is expanded; (2) the product of the invention is in a flowing liquid state, has stable state, can not be layered and precipitated after being placed for a long time, and can be uniformly dispersed in water; (3) the water-soluble rosemary fat-soluble antioxidant is simple in preparation method and low in cost, and can be produced and applied in a large scale.
Detailed Description
To better illustrate the objects, aspects and advantages of the present invention, the present invention will be further described with reference to specific examples.
Example 1
One embodiment of the water-soluble rosemary antioxidant comprises a powdery rosemary liposoluble antioxidant, tween 80, polyglycerol fatty acid ester and monoglyceride, wherein the mass ratio of the powdery rosemary liposoluble antioxidant to the tween 80 to the polyglycerol fatty acid ester to the monoglyceride is 1: 2: 0.1: 0.1.
example 2
One embodiment of the water-soluble rosemary antioxidant comprises powdered rosemary fat-soluble antioxidant, tween 80, polyglycerol fatty acid ester and monoglyceride, wherein the mass ratio of the powdered rosemary fat-soluble antioxidant to the tween 80 to the polyglycerol fatty acid ester to the monoglyceride is 5: 5: 0.5: 0.5.
example 3
One embodiment of the water-soluble rosemary antioxidant comprises a powdery rosemary liposoluble antioxidant, tween 80, polyglycerol fatty acid ester and monoglyceride, wherein the mass ratio of the powdery rosemary liposoluble antioxidant to the tween 80 to the polyglycerol fatty acid ester to the monoglyceride is 2: 4: 0.3: 0.2.
example 4
One embodiment of the water-soluble rosemary antioxidant comprises a powdery rosemary liposoluble antioxidant, tween 80, polyglycerol fatty acid ester and monoglyceride, wherein the mass ratio of the powdery rosemary liposoluble antioxidant to the tween 80 to the polyglycerol fatty acid ester to the monoglyceride is 4: 3: 0.2: 0.3.
example 5
One embodiment of the water-soluble rosemary antioxidant comprises a powdery rosemary liposoluble antioxidant, tween 80, polyglycerol fatty acid ester and monoglyceride, wherein the mass ratio of the powdery rosemary liposoluble antioxidant to the tween 80 to the polyglycerol fatty acid ester to the monoglyceride is 1: 4: 0.4: 0.4.
example 6
One embodiment of the method for preparing a water-soluble rosemary antioxidant of the present invention comprises the following steps: weighing the powdery rosemary liposoluble antioxidant, tween 80, polyglycerol fatty acid ester and monoglyceride according to a certain proportion, stirring at a constant temperature of 70 ℃ for 20min, and cooling to obtain the rosemary liposoluble antioxidant.
Example 7
One embodiment of the method for preparing a water-soluble rosemary antioxidant of the present invention comprises the following steps: weighing the powdery rosemary liposoluble antioxidant, tween 80, polyglycerol fatty acid ester and monoglyceride according to a certain proportion, stirring at a constant temperature of 50 ℃ for 40min, and cooling to obtain the rosemary liposoluble antioxidant.
Example 8
One embodiment of the method for preparing a water-soluble rosemary antioxidant of the present invention comprises the following steps: weighing the powdery rosemary liposoluble antioxidant, tween 80, polyglycerol fatty acid ester and monoglyceride according to a certain proportion, stirring at a constant temperature of 60 ℃ for 30min, and cooling to obtain the rosemary liposoluble antioxidant.
Example 9
In this example, the water solubility of the water-soluble rosemary antioxidants of examples 1 to 5 was examined.
First, experiment method
The water-soluble rosemary antioxidant obtained in examples 1 to 5 was used (the preparation method was the same as in example 8), and a control group was prepared in which the rosemary fat-soluble antioxidant was obtained from the powdery rosemary fat-soluble antioxidant component in the water-soluble rosemary antioxidant of the present invention. The water-soluble rosemary antioxidant obtained in examples 1 to 5 and the powdery rosemary fat-soluble antioxidant of the control group were dissolved in water at a ratio of 0.1%, and the dissolution behavior of the antioxidants of each group was observed.
Second, experimental results
The solubility behavior of each group of antioxidants in water is shown in table 1:
TABLE 1 results of the experiment
From the above experimental results, it can be seen that the rosemary antioxidant provided by the invention (examples 1 to 5) has very good solubility in water, high dissolution rate, stable state, no delamination and no precipitation after long-term storage, and can be uniformly dispersed in water. The best results are obtained in example 5. Whereas the powdered rosemary fat-soluble antioxidant of the control group was not dissolved at all in water.
Example 10
The invention discloses a water-soluble rosemary antioxidant, which comprises a powdery rosemary fat-soluble antioxidant, Tween 80, polyglycerol fatty acid ester and monoglyceride, wherein the mass ratio of the powdery rosemary fat-soluble antioxidant to the Tween 80 to the polyglycerol fatty acid ester to the monoglyceride is (1-5): (2-5):(0.1-0.5):(0.1-0.5). The usage amount of each raw material is obtained by a great deal of research and statistical analysis of the inventor, and the antioxidant can be ensured to have good water solubility in the ratio range. This example investigated the effect of raw material usage on antioxidant water solubility.
First, experimental design
In order to study the influence of the usage amount of the raw materials on the water solubility of the water-soluble rosemary antioxidant, experimental groups 1-3 and control groups 1-4 were designed, and are specifically shown in table 2. Groups of water soluble rosemary antioxidants were prepared as in example 8.
TABLE 2 Experimental design
Second, detection method
The water solubility of the water soluble rosemary antioxidants was determined as in example 9. Third, experimental results
The results of the water solubility test for water soluble rosemary antioxidants for each group are shown in table 3:
TABLE 3 results of the experiment
From the above experimental results, it can be seen that the mass ratio of the powdered rosemary fat-soluble antioxidant, tween 80, polyglycerol fatty acid ester and monoglyceride is (1-5): (2-5): (0.1-0.5): 0.1-0.5) the rosemary antioxidant prepared has the best water solubility (experimental groups 1-3), and the water-soluble effect of the rosemary lipid-soluble antioxidant is obviously influenced by the amount of the raw materials which are not within the range (control groups 1-4).
Finally, it should be noted that the above embodiments are only used for illustrating the technical solutions of the present invention and not for limiting the protection scope of the present invention, and although the present invention is described in detail with reference to the preferred embodiments, it should be understood by those skilled in the art that modifications or equivalent substitutions can be made on the technical solutions of the present invention without departing from the spirit and scope of the technical solutions of the present invention.
Claims (7)
1. The water-soluble rosemary antioxidant is characterized by comprising a powdery rosemary fat-soluble antioxidant, Tween 80, polyglycerol fatty acid ester and monoglyceride, wherein the mass ratio of the powdery rosemary fat-soluble antioxidant to the Tween 80 to the polyglycerol fatty acid ester to the monoglyceride is (1-5): (2-5): (0.1-0.5): (0.1-0.5).
2. A water soluble rosemary antioxidant according to claim 1, wherein the powdered rosemary lipid soluble antioxidant, tween 80, polyglycerol fatty acid ester and monoglyceride are present in a mass ratio of 2: 4: 0.3: 0.2.
3. a water soluble rosemary antioxidant according to claim 1, wherein the powdered rosemary lipid soluble antioxidant, tween 80, polyglycerol fatty acid ester and monoglyceride are present in a mass ratio of 4: 3: 0.2: 0.3.
4. a water soluble rosemary antioxidant according to claim 1, wherein the powdered rosemary lipid soluble antioxidant, tween 80, polyglycerol fatty acid ester and monoglyceride are present in a mass ratio of 1: 4: 0.4: 0.4.
5. a process for the preparation of a water soluble rosemary antioxidant according to any of the claims 1 to 4 comprising the steps of: weighing the powdery rosemary fat-soluble antioxidant, the Tween 80, the polyglycerol fatty acid ester and the monoglyceride according to the proportion, stirring at the constant temperature of 50-70 ℃ for 20-40 min, and cooling to obtain the rosemary fat-soluble antioxidant.
6. The method according to claim 5, wherein the powdered rosemary lipid-soluble antioxidant, Tween 80, polyglycerin fatty acid ester and monoglyceride are stirred at a constant temperature of 60 ℃ for 30min and cooled to obtain the rosemary lipid-soluble antioxidant.
7. Use of a water-soluble rosemary antioxidant according to any one of claims 1 to 4 in the preparation of a medicament, a food product and a cosmetic product.
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| KR20170004712A (en) * | 2015-07-03 | 2017-01-11 | 주식회사 다인소재 | Preparation method of rosemary extract by enzyme treatment, and water-soluble antioxidant composition comprising the same |
| CN106509585A (en) * | 2015-09-09 | 2017-03-22 | 易大军 | High-efficiency safe food oxidation-resistant fresh-keeping agent |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN102604640A (en) * | 2011-01-19 | 2012-07-25 | 广州合诚三先生物科技有限公司 | Method for comprehensively extracting rosmarinus officinalis and preparing fat-soluble instant antioxidant |
| CN102293261A (en) * | 2011-07-12 | 2011-12-28 | 中国农业大学 | Waterless biscuit oil and preparation method thereof |
| CN103462173A (en) * | 2013-09-23 | 2013-12-25 | 天津春发生物科技集团有限公司 | Composite antioxidant with emulsifying property and use method thereof |
| KR20170004712A (en) * | 2015-07-03 | 2017-01-11 | 주식회사 다인소재 | Preparation method of rosemary extract by enzyme treatment, and water-soluble antioxidant composition comprising the same |
| CN106509585A (en) * | 2015-09-09 | 2017-03-22 | 易大军 | High-efficiency safe food oxidation-resistant fresh-keeping agent |
| CN105124546A (en) * | 2015-09-24 | 2015-12-09 | 珠海雅富兴源食品工业有限公司 | Preparation method of natural carotene preparation |
| CN105360273A (en) * | 2015-11-23 | 2016-03-02 | 江南大学 | Longsnout catfish fillet coating antistaling agent, preparation method and fresh-keeping method thereof |
| CN106036355A (en) * | 2016-08-20 | 2016-10-26 | 陈爱梅 | Preparation method of antioxidant |
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