CN108159129A - It is a kind of for pharmaceutical composition of knife sore wound and preparation method thereof and purposes - Google Patents
It is a kind of for pharmaceutical composition of knife sore wound and preparation method thereof and purposes Download PDFInfo
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- CN108159129A CN108159129A CN201810122540.5A CN201810122540A CN108159129A CN 108159129 A CN108159129 A CN 108159129A CN 201810122540 A CN201810122540 A CN 201810122540A CN 108159129 A CN108159129 A CN 108159129A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/18—Iodine; Compounds thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/02—Medicinal preparations containing materials or reaction products thereof with undetermined constitution from inanimate materials
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/19—Acanthaceae (Acanthus family)
- A61K36/195—Strobilanthes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/31—Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
- A61K36/315—Isatis, e.g. Dyer's woad
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/54—Lauraceae (Laurel family), e.g. cinnamon or sassafras
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
- A61K36/704—Polygonum, e.g. knotweed
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Abstract
The invention discloses a kind of for pharmaceutical composition of knife sore wound and preparation method thereof and purposes, which counts in parts by weight includes：White 280 ~ 320 parts of keel, 4 ~ 6 parts of Borneolum, 4 ~ 6 parts of iodoform, 45 ~ 55 parts of indigo naturalis, 120 ~ 150 parts of camphor.Preferably, the composition is counted include in parts by weight：White 300 parts of keel, 5 parts of Borneolum, 5 parts of iodoform, 50 parts of indigo naturalis, 140 parts of camphor.It is highly preferred that the composition includes by weight：White keel 30g, Borneolum 0.5g, iodoform 0.5g, indigo naturalis 5g, camphor 14g；The common 50g compositions dose of all the components.The present invention also provides the preparation methods and purposes of the pharmaceutical composition.Pharmaceutical composition provided by the present invention for knife sore wound and preparation method thereof and purposes, have the characteristics that reasonable recipe, dosage it is few, it is significant in efficacy, have no toxic side effect, be rapidly reached effect.
Description
Technical field
The present invention relates to a kind of pharmaceutical composition for curing mainly traumatic injury and preparation method thereof and purposes, and in particular, to
It is a kind of for pharmaceutical composition of knife sore wound and preparation method thereof and purposes.
Background technology
Bruise damage, exterior trauma are the common wounds of integrative therapy.Traumatic hemorrhage needs hemostasis in time, Massive Bleeding
When can cause to suffer a shock, cause life danger, while bleeding is also with pain, inflammation etc..If bleeding cannot stop blooding in time, can
It deposits in vivo, macrophage phagocytosis bacterium, initiationization takes or cause other diseases.Therefore, haemostatic medicament is clinically without can
What is substituted must use product, have the characteristics that Clinical practice compliance is strong.
In the prior art, the various traumatic hemorrhages of whole body skin, the method for especially treating knife wound, sore wound, golden wound etc.
Typically using suture, then with composite medicine, injection treatment, achieve the purpose that anti-inflammatory.But at present both at home and abroad to bone traumatism, bruise
The therapeutic effect of damage is unsatisfactory.Since western medical treatment is mostly using operation and oral drug therapy, the trouble that operative treatment has
Person cannot receive, and oral drug therapy side effect is larger, can bring stimulating gastrointestinal, cause upset,gastro-intestinal, thrombosis induces the heart
Cranial vascular disease causes blood pressure drastically to increase, the toxic side effects such as allergic reaction.In Chinese traditional treatment, oral medicinal herb is all multiple
Side, therefore have the shortcomings that taking dose is big, purity is not high, quality is unstable, unsatisfactory curative effect.And the knife sore medicine or gold of external application
Sore medicine cures mainly the damage of knife axe, falls servant and smash i.e. traumatic injury, although disclosing a certain number of test in the Chinese medicine preparation in China
Side, but there are it is effective slowly, the course for the treatment of is long the shortcomings that.
Invention content
The object of the present invention is to provide a kind of for more effectively treating the medicine of bone traumatism, traumatic injury, external wound etc.
Compositions and preparation method thereof and purposes can solve existing issue, without suture, only can just cure the whole body with externally applied Chinese medicine
Stain caused by the various traumatic hemorrhages of skin, especially knife wound, bullet wound are shown in blood person and the various causes of disease is rotten etc..
In order to achieve the above object, the present invention provides a kind of pharmaceutical composition, wherein, the composition is counted in parts by weight
Comprising：White 280 ~ 320 parts of keel, 4 ~ 6 parts of Borneolum, 4 ~ 6 parts of iodoform, 45 ~ 55 parts of indigo naturalis, 120 ~ 150 parts of camphor.White keel are Gu
In generation, large-scale mammal was as the fossil of the bones such as class, Hippocampal cortex class, rhinoceros class, deer class, ox class；Gas, taste：It is sweet, flat, nontoxic, puckery,
It is cool, nontoxic；It is demented to cure mainly frightened epilepsy, palpitation is forgetful, insomnia and dreamful sleep, spontaneous sweating, and stranguria with turbid discharge of passing out semen, hematemesis is had blood in stool, under uterine bleeding band, rushed down
Dysentery rectal prolapse, ulcer do not close up long.Trunk extraction crystallization of the Borneolum for Spore density kapur, gas faint scent, acrid flavour, cool, tool
Volatility, the thoughts of returning home, spleen, lung channel cure mainly logical all keys, dissipate stagnated fire, swelling and pain relieving, go screen improving eyesight, for apoplexy lockjaw, frightened carbuncle phlegm
Larynx numbness dentalgia, aphtha Yong Yi, hot eyes skin screen are controlled in fan, external application.Iodoform is also iodoform, is pharmaceutically used as disinfectant, and general wound should
With must not exceed 2g.Indigo naturalis is justicia reward section plant acanthaceous indigo, polygonaceae plant indigo plant, the leaf of cruciferae isatis or cauline leaf warp
Dried powder made from processing, agglomerate or particle, nature and flavor are salty, cold, return liver warp, clearing heat and detoxicating, blood cooling and ecchymoses removing, purging intense heat arresting convulsion, main
Control febrile virulent maculae, blood-head tells nosebleed, pectoralgia hemoptysis, aphtha, mumps, larynx numbness, pediatric epilepsy scared.Camphor for canella camphor tree root, it is dry,
Branch, leaf, through crystalline particulate made of refinement；Nature and flavor are pungent, warm, enter the heart, spleen two passes through, and enter meridian of Foot-JUE YIN；Sensible, desinsection, analgesic,
It wards off dirty, cures mainly trusted subordinate's distending pain, tinea pedis, sore mange, toothache, traumatic injury.
Above-mentioned pharmaceutical composition, wherein, preferably meter includes the composition in parts by weight：White 300 parts of keel,
5 parts of Borneolum, 5 parts of iodoform, 50 parts of indigo naturalis, 140 parts of camphor.
Above-mentioned pharmaceutical composition, wherein, the composition more preferably includes by weight：White keel 30g, Borneolum
0.5g, iodoform 0.5g, indigo naturalis 5g, camphor 14g；The common 50g compositions dose of all the components.
The present invention also provides the preparation method of above-mentioned pharmaceutical composition, wherein, the method is：It weighs in proportion
Each drug, grinds and is sieved respectively, is then uniformly mixed, last bagging and packaging.
The preparation method of above-mentioned pharmaceutical composition, wherein, the particle size range ground in the method be less than or
Equal to 300 mesh.
The preparation method of above-mentioned pharmaceutical composition, wherein, the bagging and packaging in the method, the solid in every bag
Grain weight is 50g.
Present invention provides the purposes of pharmaceutical composition prepared by above-mentioned method, wherein, the pharmaceutical composition
It is used to prepare the externally applied formulation of knife sore wound.
The purposes of above-mentioned pharmaceutical composition, wherein, the pharmaceutical composition is externally applied to wound affected part when in use.
Pharmaceutical composition provided by the present invention for knife sore wound and preparation method thereof has the following advantages with purposes：
The treatment bruise that pharmaceutical composition provided by the present invention is a kind of short treating period, curative effect is high, is had no adverse reaction with side effect
The Chinese medicine preparation of damage, have the characteristics that reasonable recipe, dosage it is few, it is significant in efficacy, have no toxic side effect, be rapidly reached effect.This
Invention is directed to the various bleedings of whole body skin injury, such as：Knife wound, sore wound, golden wound, sinus, festers, hemorrhoid hemorrhage, sugar at bullet wound
Sick wound open-ended of urine etc. has the effect of notable, can quick-acting haemostatic powder, the speed that cicatrizes a wound compared with the prior art faster, can
It is strong to rapidly promote cytothesis, reactivity, imposes on affected part layer by layer deeply, each layer damaged part is made to heal rapidly, sees up to vertical pole
, there is the wounded in the effect of shadow good therapeutic effect, and has sedation.Traditional wound can partly be replaced using the present invention
The therapeutic modality that must be sutured, scar is small or without scar after good analgesic effect, healing.
Specific embodiment
The specific embodiment of the present invention is further described below.
Pharmaceutical composition provided by the invention is counted in parts by weight to be included：White 280 ~ 320 parts of keel, 4 ~ 6 parts of Borneolum, iodoform
4 ~ 6 parts, 45 ~ 55 parts of indigo naturalis, 120 ~ 150 parts of camphor.
Preferably, the composition is counted include in parts by weight：White 300 parts of keel, 5 parts of Borneolum, 5 parts of iodoform, 50 parts of indigo naturalis,
140 parts of camphor.
It is highly preferred that the composition includes by weight：White keel 30g, Borneolum 0.5g, iodoform 0.5g, indigo naturalis 5g, camphor
14g；The common 50g compositions dose of all the components.
White keel are ancient times large size mammal as the fossil of the bones such as class, Hippocampal cortex class, rhinoceros class, deer class, ox class；
Gas, taste：It is sweet, flat, nontoxic, it is puckery, cool, nontoxic；It is demented to cure mainly frightened epilepsy, palpitation is forgetful, insomnia and dreamful sleep, spontaneous sweating, stranguria with turbid discharge of passing out semen,
Hematemesis is had blood in stool, and under uterine bleeding band, rush down dysentery rectal prolapse, ulcer does not close up long.Trunk extraction knot of the Borneolum for Spore density kapur
Crystalline substance, gas faint scent, acrid flavour, cool, tool volatility, the thoughts of returning home, spleen, lung channel cure mainly logical all keys, dissipate stagnated fire, swelling and pain relieving, go screen improving eyesight,
For apoplexy lockjaw, frightened carbuncle phlegm confusing heart, larynx numbness dentalgia, aphtha Yong Yi, hot eyes skin screen are controlled in external application.Iodoform is also iodoform, pharmaceutically uses
Disinfectant is made, general wound application must not exceed 2g.Indigo naturalis is justicia reward section plant acanthaceous indigo, polygonaceae plant indigo plant, Cruciferae
The processed dried powder obtained of the leaf or cauline leaf of plant woaded blue, agglomerate or particle, nature and flavor are salty, cold, return liver warp, clearing heat and detoxicating,
Blood cooling and ecchymoses removing, purging intense heat arresting convulsion, cure mainly febrile virulent maculae, blood-head tells nosebleed, pectoralgia hemoptysis, aphtha, mumps, larynx numbness, pediatric epilepsy scared.Camphor
Root, dry, branch, leaf for canella camphor tree, through crystalline particulate made of refinement；Nature and flavor are pungent, warm, enter the heart, spleen two passes through, and enter foot and faint
Yin channel；Sensible, desinsection relieves pain, wards off dirty, cures mainly trusted subordinate's distending pain, tinea pedis, sore mange, toothache, traumatic injury.
The present invention also provides the preparation methods of the pharmaceutical composition, weigh each drug in proportion, grind respectively simultaneously
Sieving, is then uniformly mixed, last bagging and packaging.
Preferably, the particle size range ground in this method is less than or equal to 300 mesh；Consolidating in every bag of bagging and packaging
Body particle weight is 50g.
Present invention provides the purposes of pharmaceutical composition prepared by this method, which is used to prepare outside knife sore
The externally applied formulation of wound is externally applied to wound affected part when in use.
With reference to embodiment to pharmaceutical composition provided by the present invention for knife sore wound and preparation method thereof with
Way is further described.
Embodiment 1 ~ 4
Material composition proportioning shown in each embodiment difference according to the form below 1 prepares pharmaceutical composition.Each raw material corresponds with accordingly
National standard.
The list of ingredients of 1. pharmaceutical composition of table（By weight）.
The present invention also provides the preparation method of the pharmaceutical composition of each embodiment and the drugs of each embodiment prepared
The purposes of composition.
Each drug in pharmaceutical composition is weighed in proportion, is ground and is sieved respectively, particle size range is less than or equal to
300 mesh, are then uniformly mixed, last bagging and packaging, and the solid particle weight in every bag is 50g.
The pharmaceutical composition is used to prepare the externally applied formulation of knife sore wound, is externally applied to wound affected part when in use.
Using the pharmaceutical composition prepared by the embodiment of the present invention 1, to nearly over thousands of example bone traumatism, traumatic injury and traumatic
The patient of wound has carried out the diagnosis and treatment based on an overall analysis of the illness and the patient's condition clinical test of Syndrome Types of TCM, efficient up to more than 98%, obvious effective rate reach 95% with
On, cure rate reaches 92%.
Pharmaceutical composition provided by the present invention for knife sore wound and preparation method thereof and purposes, the pharmaceutical composition are
The clinical test of many cases is have passed through, to its function per taste Chinese medicine with curing mainly and being formed according to the research of modern Chinese herbal medicine pharmacology
A kind for the treatment of prescription for treating traumatic injury, there is scientific formulation is reasonable, production method is simple and practicable, easy to spread spy
Point, short treating period, curative effect are high, medical expense is low, have no adverse reaction and side effect.
Although present disclosure is discussed in detail by above preferred embodiment, but it should be appreciated that above-mentioned
Description is not considered as limitation of the present invention.After those skilled in the art have read the above, for the present invention's
A variety of modifications and substitutions all will be apparent.Therefore, protection scope of the present invention should be limited to the appended claims.
Claims (8)
1. a kind of pharmaceutical composition for knife sore wound, which is characterized in that the composition is counted include in parts by weight：
White 280 ~ 320 parts of keel, 4 ~ 6 parts of Borneolum, 4 ~ 6 parts of iodoform, 45 ~ 55 parts of indigo naturalis, 120 ~ 150 parts of camphor.
2. it to be used for the pharmaceutical composition of knife sore wound as described in claim 1, which is characterized in that the composition is by weight
Number meter includes：
White 300 parts of keel, 5 parts of Borneolum, 5 parts of iodoform, 50 parts of indigo naturalis, 140 parts of camphor.
3. it to be used for the pharmaceutical composition of knife sore wound as claimed in claim 2, which is characterized in that the composition is by weight
Meter includes：
White keel 30g, Borneolum 0.5g, iodoform 0.5g, indigo naturalis 5g, camphor 14g；
The common 50g compositions dose of all the components.
4. a kind of preparation method of pharmaceutical composition for knife sore wound as described in any one in claim 1 ~ 3,
It is characterized in that, the method is：Each drug is weighed in proportion, grinds and is sieved respectively, is then uniformly mixed, and is finally sealed
Bag packaging.
5. as claimed in claim 4 for the preparation method of the pharmaceutical composition of knife sore wound, which is characterized in that the side
The particle size range ground in method is less than or equal to 300 mesh.
6. as claimed in claim 4 for the preparation method of the pharmaceutical composition of knife sore wound, which is characterized in that the side
Bagging and packaging in method, the solid particle weight in every bag are 50g.
A kind of 7. purposes of pharmaceutical composition prepared by method as claimed in claim 4, which is characterized in that the medicine group
Close the externally applied formulation that object is used for knife sore wound.
8. the purposes of pharmaceutical composition as claimed in claim 7, which is characterized in that the pharmaceutical composition is outer when in use
Spread on wound affected part.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810122540.5A CN108159129A (en) | 2018-02-07 | 2018-02-07 | It is a kind of for pharmaceutical composition of knife sore wound and preparation method thereof and purposes |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810122540.5A CN108159129A (en) | 2018-02-07 | 2018-02-07 | It is a kind of for pharmaceutical composition of knife sore wound and preparation method thereof and purposes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN108159129A true CN108159129A (en) | 2018-06-15 |
Family
ID=62513088
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810122540.5A Pending CN108159129A (en) | 2018-02-07 | 2018-02-07 | It is a kind of for pharmaceutical composition of knife sore wound and preparation method thereof and purposes |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN108159129A (en) |
-
2018
- 2018-02-07 CN CN201810122540.5A patent/CN108159129A/en active Pending
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| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20180615 |
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| RJ01 | Rejection of invention patent application after publication |