CN108148754A - A kind of double ejecting devices of 3D biometric prints - Google Patents

A kind of double ejecting devices of 3D biometric prints Download PDF

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Publication number
CN108148754A
CN108148754A CN201810051026.7A CN201810051026A CN108148754A CN 108148754 A CN108148754 A CN 108148754A CN 201810051026 A CN201810051026 A CN 201810051026A CN 108148754 A CN108148754 A CN 108148754A
Authority
CN
China
Prior art keywords
nozzle
fixed seat
straight line
driving mechanism
line driving
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201810051026.7A
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Chinese (zh)
Inventor
张琦
陈冬冬
周骥平
姜娅妮
吴鹏鹏
梁国栋
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yangzhou University
Original Assignee
Yangzhou University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yangzhou University filed Critical Yangzhou University
Priority to CN201810051026.7A priority Critical patent/CN108148754A/en
Publication of CN108148754A publication Critical patent/CN108148754A/en
Pending legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M33/00Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus

Abstract

The invention discloses a kind of double ejecting devices of 3D biometric prints, including electric rotating machine, connecting shaft, straight line driving mechanism, nozzle, fixed seat;The fixed seat upper end is connected by connecting shaft with the rotation axis of electric rotating machine;It is monosymmetric in the fixed seat to be equipped with straight line driving mechanism;The nozzle is two, is symmetricly set on the straight line driving mechanism of both sides;The straight line driving mechanism can drive nozzle horizontal linear in fixed seat to slide;Single nozzle printing can be realized in the double ejecting devices of 3D biometric prints of the present invention, can also realize double nozzle printings;The switching frequency that nozzle can be reduced improves the efficiency of printing;It can realize the one-pass molding printing of two kinds of biomass composites, the survival rate of cell after printing can be improved, suitable for a variety of biological materials, use scope is extensive.

Description

A kind of double ejecting devices of 3D biometric prints
Technical field
The invention belongs to field of tissue engineering technology, the double ejecting devices of particularly a kind of 3D biometric prints.
Background technology
For being damaged the treatment of bulk soft tissue and internal organs, the transplanting of human tissue organ is a kind of extremely effective Therapy.But since the shortage of organ donor source, the problems such as immunological rejection exist, organ transplant is treated in practice In the presence of the difficulty for being difficult to overcome.And biological 3D printing technique utilizes CAD, the method by being layering will be thin Born of the same parents, cellular matrix and other biological material framework three-dimensional racks, with certain porosity, generation has certain function Living human's organ-tissue.
Current 3D biometric prints method or relatively simple in 3D organizational projects are built, is only capable of the biology of printing list one Material, during compound bio material is continually developed, it is necessary to printing is carried out at the same time to a variety of biomaterials, and it is single The printing equipment of nozzle needs constantly to switch nozzle, troublesome in poeration.
Invention content
Technical problem solved by the invention is to provide a kind of 3D biometric prints double ejecting devices, to solve existing beat Printing equipment puts single nozzle, the problem of being only capable of the biomaterial of printing list one.
Realize the object of the invention technical solution be:
The double ejecting devices of a kind of 3D biometric prints, including electric rotating machine, connecting shaft, straight line driving mechanism, nozzle, fixation Seat;
The fixed seat upper end is connected by connecting shaft with the rotation axis of electric rotating machine;It is monosymmetric in the fixed seat Equipped with straight line driving mechanism;The nozzle is two, is symmetricly set on the straight line driving mechanism of both sides;The straight line driving mechanism Nozzle horizontal linear in fixed seat can be driven to slide.
Compared with prior art, the present invention its remarkable advantage:
(1) single nozzle printing can be realized in the double ejecting devices of 3D biometric prints of the invention, can also realize double nozzle printings; The switching frequency that nozzle can be reduced improves the efficiency of printing.
(2) single nozzle printing can be realized in the double ejecting devices of 3D biometric prints of the invention, is driven by electric rotating machine solid Reservation rotates, and realizes the printing of multi-angle, so as to flexibly build complicated organizational project;It can realize two kinds of biomass The one-pass molding printing of composite material, can improve the survival rate of cell after printing, suitable for a variety of biological materials, use model It encloses extensively.
(3) the double ejecting devices of 3D biometric prints of the invention by straight line driving mechanism, it can be achieved that nozzle level prints position That puts freely adjusts.
The present invention is described in further detail below in conjunction with the accompanying drawings.
Description of the drawings
Fig. 1 is the front view of the double ejecting devices of 3D biometric prints of the present invention.
Fig. 2 is the left view of the double ejecting devices of 3D biometric prints of the present invention.
Specific embodiment
In order to illustrate technical scheme of the present invention and technical purpose, below in conjunction with the accompanying drawings and specific embodiment is the present invention It is further to introduce.
With reference to Fig. 1, a kind of double ejecting devices of 3D biometric prints of the invention drive including electric rotating machine 1, connecting shaft 2, straight line Motivation structure, nozzle 5, fixed seat 8;
8 upper end of fixed seat is connected by connecting shaft 2 with the rotation axis of electric rotating machine 1;Both sides pair in the fixed seat 8 What is claimed is equipped with straight line driving mechanism;The nozzle 5 is two, is symmetricly set on the straight line driving mechanism of both sides;The straight line drives Motivation structure can drive the horizontal linear in fixed seat 8 of nozzle 5 to slide.
In some embodiments, the straight line driving mechanism includes driving motor 4, ball-screw;The driving motor 4 Drive shaft be connected with ball-screw.The ball-screw is arranged on by two spring bearings in fixed seat 8, ball-screw Feed screw nut is connected by ball nut with sliding block, and the nozzle 5 is fixed on sliding block.Driving motor 4 rotates, and drives ball wire Thick stick rotates, and is further driven to nozzle 5 and moves horizontally, so as to fulfill freely adjusting for 5 horizontal print position of nozzle.
Further, above-mentioned driving motor 4 controls dc motor using PMW, the speed of motor can be carried out smooth The adjustment of property.
As shown in Fig. 2, in other embodiment, the straight line driving mechanism includes driving motor 4, sliding block 6, slides Rail;The driving motor 4 is linear stepping motor;Linear stepping motor is connected with sliding block 6, and the sliding rail is arranged on fixed seat 8 On, sliding block 6 coordinates with sliding rail;The nozzle 5 is fixed on sliding block 6, and driving motor band movable slider 6 is transported along sliding rail horizontal linear It is dynamic, it is further driven to nozzle 5 and moves horizontally, so as to fulfill the adjustment of 5 print position of nozzle.
Further, shutter 10 is additionally provided on the sliding rail, dust-proof effect can be played.
Single nozzle printing can be realized in the double ejecting devices of 3D biometric prints of the present invention, can also realize double nozzle printings;When When need to complete the printing of two kinds of biomaterials simultaneously, after the nozzle 5 of one end completes printing, electric rotating machine 1 rotates fixed seat 8 180 °, the nozzle 5 of the other end proceeds by the printing of second of biomaterial;It need to only be loaded in the nozzle 5 at both ends different Biological material is so as to printing different compound mixed biologic materials.It can realize two kinds of one layer one of biological materials It is laminated plus different materials, the number for reducing nozzle switching is decreased in print procedure simultaneously, the heat that printing equipment generates Measure the influence to biological material.Particularly print competent cell, extracellular matrix, growth factor and biomaterial.It is beating Electric rotating machine 1 can also be opened during print and realizes that the printing of multi-angle promotes the structure of complicated organizational project.The present invention It can realize the isochronous printing of cell and biological material, improve the efficiency of 3D biometric prints.

Claims (5)

1. the double ejecting devices of a kind of 3D biometric prints, which is characterized in that including electric rotating machine (1), connecting shaft (2), linear drives Mechanism, nozzle (5), fixed seat (8);
Fixed seat (8) upper end is connected by connecting shaft (2) with the rotation axis of electric rotating machine (1);Two on the fixed seat (8) Side is symmetrically equipped with straight line driving mechanism;The nozzle (5) is two, is symmetricly set on the straight line driving mechanism of both sides;It is described Straight line driving mechanism can drive nozzle (5) horizontal linear in fixed seat (8) to slide.
A kind of 2. double ejecting devices of 3D biometric prints according to claim 1, which is characterized in that the straight line driving mechanism Including driving motor (4), ball-screw;The drive shaft of the driving motor (4) is connected with ball-screw;The ball-screw leads to It crosses two spring bearings to be arranged in fixed seat (8), the feed screw nut of ball-screw is connected by ball nut with sliding block, described Nozzle (5) is fixed on sliding block;Driving motor (4) rotates, and drives ball screw turns, is further driven to the horizontal shifting of nozzle (5) It is dynamic, so as to fulfill freely adjusting for nozzle (5) horizontal print position.
A kind of 3. double ejecting devices of 3D biometric prints according to claim 2, which is characterized in that the driving motor (4) Dc motor is controlled using PMW.
A kind of 4. double ejecting devices of 3D biometric prints according to claim 1, which is characterized in that the straight line driving mechanism Including driving motor (4), sliding block (6), sliding rail;The driving motor (4) is linear stepping motor;Linear stepping motor and sliding block (6) it is connected, the sliding rail is arranged in fixed seat (8), and sliding block (6) coordinates with sliding rail;The nozzle (5) is fixed on sliding block (6) On, driving motor band movable slider (6) is further driven to nozzle (5) and moves horizontally, so as to fulfill spray along sliding rail horizontal rectilinear motion The adjustment of head (5) print position.
5. the double ejecting devices of a kind of 3D biometric prints according to claim 4, which is characterized in that be additionally provided on the sliding rail Shutter (10).
CN201810051026.7A 2018-01-19 2018-01-19 A kind of double ejecting devices of 3D biometric prints Pending CN108148754A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201810051026.7A CN108148754A (en) 2018-01-19 2018-01-19 A kind of double ejecting devices of 3D biometric prints

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201810051026.7A CN108148754A (en) 2018-01-19 2018-01-19 A kind of double ejecting devices of 3D biometric prints

Publications (1)

Publication Number Publication Date
CN108148754A true CN108148754A (en) 2018-06-12

Family

ID=62461569

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201810051026.7A Pending CN108148754A (en) 2018-01-19 2018-01-19 A kind of double ejecting devices of 3D biometric prints

Country Status (1)

Country Link
CN (1) CN108148754A (en)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106137457A (en) * 2015-04-24 2016-11-23 周惠兴 A kind of manufacturing platform system printed for 3D blood vessel
US20170198252A1 (en) * 2014-09-05 2017-07-13 Private Institution Lab For Biotechnological Research "3D Bioprinting Solutions" Device and methods for printing biological tissues and organs
CN107028681A (en) * 2017-04-11 2017-08-11 清华大学深圳研究生院 A kind of 3D printing device and method of tissue engineering bracket
CN107498865A (en) * 2017-09-14 2017-12-22 西安交通大学 A kind of rotary more material 3D printing ejecting devices

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20170198252A1 (en) * 2014-09-05 2017-07-13 Private Institution Lab For Biotechnological Research "3D Bioprinting Solutions" Device and methods for printing biological tissues and organs
CN106137457A (en) * 2015-04-24 2016-11-23 周惠兴 A kind of manufacturing platform system printed for 3D blood vessel
CN107028681A (en) * 2017-04-11 2017-08-11 清华大学深圳研究生院 A kind of 3D printing device and method of tissue engineering bracket
CN107498865A (en) * 2017-09-14 2017-12-22 西安交通大学 A kind of rotary more material 3D printing ejecting devices

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Application publication date: 20180612

RJ01 Rejection of invention patent application after publication