CN108145970B

CN108145970B - Many business turn over shower nozzle of biomaterial 3D printer

Info

Publication number: CN108145970B
Application number: CN201810006671.7A
Authority: CN
Inventors: 杨陈
Original assignee: Abe Three Di Printing Technology (chongqing) Co Ltd
Current assignee: Abe Three Di Printing Technology (chongqing) Co Ltd
Priority date: 2018-01-04
Filing date: 2018-01-04
Publication date: 2020-02-18
Anticipated expiration: 2038-01-04
Also published as: CN108145970A

Abstract

The invention relates to a multi-inlet one-outlet nozzle of a biomaterial 3D printer, which comprises a cylinder on the upper part and a cone gradually changed at the lower part of the cylinder, wherein a plurality of feeding holes are uniformly distributed in the cylinder along the circumference, the side surface of the cylinder is provided with a mounting hole for fixing the nozzle, the center of the cone is provided with a discharging hole, each feeding hole comprises a straight line section and an inclined transition section, and is communicated with the discharging hole through the inclined transition section, and the feeding holes are mutually independent and not communicated at the position communicated with the discharging hole; the lower end of the discharge hole is connected with a nozzle; the printer nozzle is made of titanium alloy. The spray head structure provided by the invention has multiple inlets and one outlet, and solves the problems that the existing biomaterial 3D printer needs multiple needle cylinders when printing multiple materials, the printing at the joint is not stable, and the materials are discontinuous.

Description

Many business turn over shower nozzle of biomaterial 3D printer

Technical Field

The invention relates to the field of materials, in particular to a multi-inlet one-outlet nozzle of a biological material 3D printer.

Background

3D printing is developed on the basis of laser cladding and rapid prototyping technology, and is a technology for constructing an object by using a powder material in a layer-by-layer printing mode on the basis of a digital model file. The method comprises the steps of layering a three-dimensional model designed in a computer to obtain a two-dimensional plane graph, printing the two-dimensional graph layer by utilizing materials made of various materials, and stacking the two-dimensional graph to form a three-dimensional entity with rapid solidification organization characteristics.

In recent years, 3D printing has become an emerging technology that is of global interest. The method is widely applied to the fields of manufacturing industry, aerospace industry and the like. The applications of 3D printing in the biomedical field are currently dominated by the manufacture of anatomical models, surgical instruments, implants and prostheses.

The development of 3D bioprinting technology has brought hope and eosin to living tissue printing and organ printing. 3D prints and is honored as the representative technique of "third industrial revolution", and 3D biological printing is the leading edge of 3D printing technique and the most abundant research field of vitality. 3D bioprinting can be defined as a novel cross-disciplined and field regenerative medical engineering technique that takes a purpose-built bioprinter as a main means, processes active materials including cells, growth factors, biomaterials, etc. as main contents, and reconstructs human tissues and organs as a main target.

Due to the particularity of the printed materials, in particular the biological materials, among which cells, gels, etc., are involved, higher demands are made on the compatibility, biocompatibility, long-term physicochemical stability, etc., of the surfaces of the printing instruments which come into contact with these materials. The traditional 3D biomaterial sprayer (needle tube) is made of copper alloy materials, and along with the development of the technology, the use requirement cannot be met more and more. However, the common titanium alloy material, such as Ti-6Al-4V alloy, has potential toxicity to human body due to the element V contained in the alloy, and cannot completely meet the requirement.

Moreover, the traditional biomaterial 3D printer mostly adopts a multi-syringe design, one material is filled in each syringe, and then the printing is performed respectively according to design requirements, although the design is simple and convenient, when different materials are switched, the unevenness and discontinuity of the joint are easily caused, and the consistency of the printed materials is poor.

Disclosure of Invention

In order to solve the problems, the invention provides a multi-inlet and one-outlet nozzle of a biomaterial 3D printer, which can solve the problems of the nozzles in the prior art.

In order to achieve the purpose, the technical scheme provided by the invention is as follows:

a biomaterial 3D printer advances one and goes out shower nozzle more, the said shower nozzle includes a cylinder and a cone that the cylinder inferior part changes gradually on the upper side, equip multiple feed ports along the circumference in the cylinder, the side of the cylinder has mounting holes to fix shower nozzle, there is a discharge opening in the centre of the cone, every feed port includes straight line section and slope transition section, and communicate with discharge opening through the slope transition section, and every feed port is independent each other, each other not communicated in the place where communicates with discharge opening; the lower end of the discharge hole is connected with a nozzle; the printer nozzle is made of titanium alloy, and the titanium alloy consists of the following components: 3.5 to 4.5 weight percent of AlAl, 1.0 to 1.4 weight percent of Zr, 2.5 to 3.5 weight percent of Cr2, 15 to 3 weight percent of Mn, 13 to 15 weight percent of Si19 to 21 weight percent of Fe1.8 to 2.2 weight percent of Cu2.2 to 2.4 weight percent of Ce0.1 to 0.2 weight percent of Ti and inevitable impurities as the rest.

Furthermore, the diameter of the cylinder is phi 38-42mm, the height is 20-30mm, the height of the cone is 25-30mm, the aperture of the straight line section of the feeding hole is phi 7-8mm, the aperture of the discharging hole is phi 4-5mm, the aperture of the inclined transition section is gradually reduced, the minimum aperture of the connection part of the inclined transition section of each feeding hole and the discharging hole is phi 1.2-2mm, and the aperture of the nozzle is phi 0.45-0.55 mm.

Further, each feeding hole on the upper surface of the cylinder is provided with an internal thread for connecting with a feeding needle cylinder; the mounting hole is provided with an internal thread for mounting, and the inner wall of the discharge hole is also provided with an internal thread and is connected with the nozzle through the thread.

Furthermore, the roughness of the inner surfaces of the feed hole and the discharge hole of the spray head is Ra0.1-Ra0.2.

Further, the spray head is formed by adopting the titanium alloy precision casting process to form a blank, then carrying out surface machining, manufacturing threads, grinding and polishing the inner walls of the feeding hole and the discharging hole.

Further, the spray head is formed by adopting titanium alloy powder prepared from the titanium alloy, then adopting a laser synchronous powder feeding additive manufacturing technology to form a blank, then carrying out surface machining, manufacturing threads, grinding and polishing the inner walls of the feed hole and the discharge hole.

Furthermore, the number of the feed holes of the multiple-inlet and one-outlet spray head is 2-8.

Furthermore, the number of the feed holes of the multiple-inlet and one-outlet spray head is 6.

The biological material comprises cells, hydrogel and other materials.

Preferably, the titanium alloy consists of the following components: 4.0wt% of Al4, 1.2 wt% of Zr, 3.0wt% of Cr3, 14 wt% of Mn, 20 wt% of Si, 2.0wt% of Fe2, 3.3 wt% of Cu0.15wt% of Ce, and the balance of Ti and inevitable impurities;

in the titanium alloy, the functions of the alloy elements are as follows:

aluminum mainly plays a role in solid solution strengthening, and the tensile strength at room temperature is increased by 50MPa when 1% of Al is added independently. In the invention, the strengthening effect is not ideal when the content of Al is less than 3.5 percent, and although the limit solubility of Al in titanium is 7.5 percent, the alloy system of the invention can generate harmful phases when the content of Al exceeds 4.5 percent; the plasticity, toughness and stress corrosion of the titanium alloy are not good.

The zirconium and the manganese are matched to play a role in supplementing and strengthening, the heat resistance is improved, the effect of singly adopting the zirconium is not ideal, particularly, the content range is adopted, Mn is taken as the main component, Zr is taken as the auxiliary component, tests show that the zirconium and the manganese are matched to have a better effect in a system, the zirconium can weaken the slow eutectoid reaction of Mn and titanium, the creep resistance is improved, and in addition, Mn can improve the welding performance.

Chromium, iron and silicon have a strengthening effect and strong β phase stabilizing capacity, wherein one part of silicon is in solid solution to improve the heat resistance, and the other part of silicon is in dispersion strengthening effect;

copper, a proper amount of copper have the effect of improving alloy toughness and corrosion resistance, and the copper also has the bactericidal effect and is favorable for the antibacterial requirement of the follow-up biomaterial 3D printer nozzle.

Cerium, dispersion strengthening, Ce in the above content range can be matched with copper to improve corrosion resistance and antibacterial action.

Compared with the prior art, the technical scheme of the invention has the following advantages:

1. the titanium alloy material developed by the invention has good mechanical property, tensile strength of 1100-1200MPa, high pressure resistance, capability of withstanding reciprocating pressure circulation and room temperature elongation of more than 20 percent, and thus, has good toughness and excellent high temperature resistance and corrosion resistance.

2. The spray head structure provided by the invention has multiple inlets and one outlet, and solves the problems that the existing biomaterial 3D printer needs multiple needle cylinders when printing multiple materials, the printing at the joint is not stable, and the materials are discontinuous.

3. The size design of the nozzle structure of the invention fully considers the smoothness of material flow, the height sizes of the cylinder and the cone determine the stability when switching materials, when the size is higher than the maximum value of the range, the material is easy to break, and when the size is lower than the minimum value of the range, the control is difficult; when the aperture of the feeding hole and the discharging hole and the smooth finish of the inner wall are not in the range, the biological material can not smoothly flow out. It is determined that the speed and flow rate of advancing the printed material is consistent with the 3D printing needs.

Drawings

Various other advantages and benefits will become apparent to those of ordinary skill in the art upon reading the following detailed description of the preferred embodiments. The drawings are only for purposes of illustrating the preferred embodiments and are not to be construed as limiting the invention. Also, like reference numerals are used to refer to like parts throughout the drawings. In the drawings:

FIG. 1 is a schematic view showing an external form of a head according to the present invention;

figure 2 shows a cross-sectional view of a spray head of the invention.

Detailed Description

Exemplary embodiments of the present disclosure will be described in more detail below with reference to the accompanying drawings. While exemplary embodiments of the present disclosure have been shown, it should be understood that the present disclosure may be embodied in various forms and should not be limited by the embodiments set forth herein. Rather, these embodiments are provided so that this disclosure will be thorough and complete, and will fully convey the scope of the disclosure to those skilled in the art.

According to the specific embodiment of the invention, a multi-inlet and one-outlet nozzle 100 of a biomaterial 3D printer is provided, the nozzle 100 comprises an upper cylinder 101 and a lower tapered cone 102, 6 feed holes 106 are uniformly distributed in the cylinder along the circumference, the side surface of the cylinder is provided with a mounting hole (not shown) for fixing the nozzle, the center of the cone is provided with a discharge hole 108, each feed hole 106 comprises a straight line section 109 and an inclined transition section 110 and is communicated with the discharge hole 108 through the inclined transition section 110, and the feed holes 106 are independent of each other and are not communicated with each other at the position where the feed holes are communicated with the discharge hole 108; the lower end of the discharge hole 108 is connected with a nozzle 103; the printer nozzle is made of titanium alloy, and the titanium alloy consists of the following components: 4.0wt% of Al4, 1.2 wt% of Zr, 3.0wt% of Cr3, 14 wt% of Mn, 20 wt% of Si, 2.0wt% of Fe2, 3.3 wt% of Cu0.15wt% of Ce, and the balance of Ti and inevitable impurities. In the implementation mode, the diameter of the cylinder is phi 40mm, the height is 25mm, the height of the cone is 27mm, the aperture of the straight line section of the feeding hole is phi 7.5mm, the aperture of the discharging hole is phi 4.5mm, the aperture of the inclined transition section is gradually reduced, the minimum aperture of the connection part of the inclined transition section of each feeding hole and the discharging hole is phi 1.5mm, and the aperture of the nozzle is phi 0.5 mm. Each feeding hole on the upper surface of the cylinder is provided with an internal thread 107 for connecting with the feeding needle cylinder 104; the needle cylinder is connected to an inlet line 105 for the drive of the material. The mounting hole is provided with an internal thread for mounting, and the inner wall of the discharge hole is also provided with an internal thread and is connected with the nozzle through the thread. The spray head is formed by adopting titanium alloy powder prepared from the titanium alloy, then adopting a laser synchronous powder feeding additive manufacturing technology to form a blank, then carrying out surface machining, manufacturing threads, grinding the inner walls of a feed hole and a discharge hole, and polishing. And controlling the roughness of the inner surfaces of the feed hole and the discharge hole of the spray head to be Ra0.1-Ra0.2.

The above description is only for the preferred embodiment of the present invention, but the scope of the present invention is not limited thereto, and any changes or substitutions that can be easily conceived by those skilled in the art within the technical scope of the present invention are included in the scope of the present invention. Therefore, the protection scope of the present invention shall be subject to the protection scope of the appended claims.

Claims

1. A biomaterial 3D printer advances a shower nozzle more, characterized by that, the said shower nozzle includes a cylinder above and a cone that the cylinder inferior part changes gradually, equip multiple feed ports along the circumference in the cylinder, the side of the cylinder has mounting holes to fix shower nozzle, there is a discharge opening in the centre of the cone, every feed port includes straight line section and slope changeover portion, and communicate with discharge opening through the slope changeover portion, the aperture of the slope changeover portion diminishes gradually, and each feed port is independent each other, each other not communicated in the place where communicates with discharge opening; the lower end of the discharge hole is connected with a nozzle; the printer nozzle is made of titanium alloy, and the titanium alloy consists of the following components: 3.5 to 4.5 weight percent of Al, 1.0 to 1.4 weight percent of Zr, 2.5 to 3.5 weight percent of Cr, 13 to 15 weight percent of Mn, 19 to 21 weight percent of Si, 1.8 to 2.2 weight percent of Fe, 2.2 to 2.4 weight percent of Cu, 0.1 to 0.2 weight percent of Ce, and the balance of Ti and inevitable impurities.

2. The biomaterial 3D printer multiple-in one-out nozzle as claimed in claim 1, wherein the cylinder has a diameter of Φ 38-42mm, a height of 20-30mm, a height of the cone of 25-30mm, a diameter of straight line segment of the feed holes of Φ 7-8mm, a diameter of discharge holes of Φ 4-5mm, a minimum diameter of the connection between the inclined transition section of each feed hole and the discharge hole of Φ 1.2-2mm, and a diameter of the nozzle of Φ 0.45-0.55 mm.

3. The biomaterial 3D printer multiple-in one-out nozzle as claimed in claim 1, wherein each feed hole on the upper surface of the cylinder is internally threaded for connection with a feed syringe; the mounting hole is provided with an internal thread for mounting, and the inner wall of the discharge hole is also provided with an internal thread and is connected with the nozzle through the thread.

4. The biomaterial 3D printer multiple-in one-out nozzle as claimed in claim 1, wherein the roughness of the inner surface of the feed hole and the discharge hole of the nozzle is ra0.1-ra0.2.

5. The biomaterial 3D printer multiple-inlet one-outlet nozzle as claimed in claim 1, wherein the nozzle is formed by adopting the titanium alloy precision casting process to form a blank, then carrying out surface machining, manufacturing threads, grinding and polishing the inner walls of the feed hole and the discharge hole.

6. The biomaterial 3D printer multiple-in one-out nozzle as claimed in claim 1, wherein the nozzle is made by using titanium alloy powder prepared from the titanium alloy, then forming a blank by using a laser synchronous powder feeding additive manufacturing technology, then performing surface machining, making threads, grinding and polishing the inner walls of a feed hole and a discharge hole.

7. The biomaterial 3D printer multiple-in one-out nozzle as claimed in claim 1, wherein the multiple-in one-out nozzle has 2-8 feed holes.

8. The biomaterial 3D printer multiple-in one-out nozzle as claimed in claim 7, wherein the number of feed holes of the multiple-in one-out nozzle is 6.