CN108138176B - 使用基于核酸引导的核酸酶的系统捕获核酸 - Google Patents
使用基于核酸引导的核酸酶的系统捕获核酸 Download PDFInfo
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- CN108138176B CN108138176B CN201680057464.3A CN201680057464A CN108138176B CN 108138176 B CN108138176 B CN 108138176B CN 201680057464 A CN201680057464 A CN 201680057464A CN 108138176 B CN108138176 B CN 108138176B
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- C12Q2521/00—Reaction characterised by the enzymatic activity
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- C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
- C12Q2525/10—Modifications characterised by
- C12Q2525/191—Modifications characterised by incorporating an adaptor
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Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
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US201562207359P | 2015-08-19 | 2015-08-19 | |
US62/207,359 | 2015-08-19 | ||
PCT/US2016/047631 WO2017031360A1 (en) | 2015-08-19 | 2016-08-18 | Capture of nucleic acids using a nucleic acid-guided nuclease-based system |
Publications (2)
Publication Number | Publication Date |
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CN108138176A CN108138176A (zh) | 2018-06-08 |
CN108138176B true CN108138176B (zh) | 2022-05-24 |
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Application Number | Title | Priority Date | Filing Date |
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CN201680057464.3A Active CN108138176B (zh) | 2015-08-19 | 2016-08-18 | 使用基于核酸引导的核酸酶的系统捕获核酸 |
Country Status (8)
Country | Link |
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US (3) | US10538758B2 (de) |
EP (2) | EP3337898B1 (de) |
JP (2) | JP6986509B2 (de) |
CN (1) | CN108138176B (de) |
AU (1) | AU2016308283B2 (de) |
CA (1) | CA2995983A1 (de) |
DK (1) | DK3337898T3 (de) |
WO (1) | WO2017031360A1 (de) |
Families Citing this family (48)
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US9359599B2 (en) | 2013-08-22 | 2016-06-07 | President And Fellows Of Harvard College | Engineered transcription activator-like effector (TALE) domains and uses thereof |
US9322037B2 (en) | 2013-09-06 | 2016-04-26 | President And Fellows Of Harvard College | Cas9-FokI fusion proteins and uses thereof |
US9340799B2 (en) | 2013-09-06 | 2016-05-17 | President And Fellows Of Harvard College | MRNA-sensing switchable gRNAs |
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AU2016308283A1 (en) | 2018-03-15 |
AU2016308283B2 (en) | 2022-04-21 |
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CN108138176A (zh) | 2018-06-08 |
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EP3337898B1 (de) | 2021-07-28 |
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JP2018529326A (ja) | 2018-10-11 |
JP6986509B2 (ja) | 2021-12-22 |
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