CN108136120A - Automatic injector - Google Patents

Automatic injector Download PDF

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Publication number
CN108136120A
CN108136120A CN201680055020.6A CN201680055020A CN108136120A CN 108136120 A CN108136120 A CN 108136120A CN 201680055020 A CN201680055020 A CN 201680055020A CN 108136120 A CN108136120 A CN 108136120A
Authority
CN
China
Prior art keywords
main body
actuating sleeve
automatic injector
projecting positions
actuating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CN201680055020.6A
Other languages
Chinese (zh)
Other versions
CN108136120B (en
Inventor
D·法比恩
O·伊斯
A·索赛
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aptar France SAS
Original Assignee
Valois SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Valois SAS filed Critical Valois SAS
Publication of CN108136120A publication Critical patent/CN108136120A/en
Application granted granted Critical
Publication of CN108136120B publication Critical patent/CN108136120B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/20Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M5/2033Spring-loaded one-shot injectors with or without automatic needle insertion
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/32Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3202Devices for protection of the needle before use, e.g. caps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/32Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3202Devices for protection of the needle before use, e.g. caps
    • A61M5/3204Needle cap remover, i.e. devices to dislodge protection cover from needle or needle hub, e.g. deshielding devices
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/32Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3205Apparatus for removing or disposing of used needles or syringes, e.g. containers; Means for protection against accidental injuries from used needles
    • A61M5/321Means for protection against accidental injuries by used needles
    • A61M5/3243Means for protection against accidental injuries by used needles being axially-extensible, e.g. protective sleeves coaxially slidable on the syringe barrel
    • A61M5/326Fully automatic sleeve extension, i.e. in which triggering of the sleeve does not require a deliberate action by the user
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/32Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3205Apparatus for removing or disposing of used needles or syringes, e.g. containers; Means for protection against accidental injuries from used needles
    • A61M5/321Means for protection against accidental injuries by used needles
    • A61M5/3243Means for protection against accidental injuries by used needles being axially-extensible, e.g. protective sleeves coaxially slidable on the syringe barrel
    • A61M5/3271Means for protection against accidental injuries by used needles being axially-extensible, e.g. protective sleeves coaxially slidable on the syringe barrel with guiding tracks for controlled sliding of needle protective sleeve from needle exposing to needle covering position
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/20Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M2005/2006Having specific accessories
    • A61M2005/2013Having specific accessories triggering of discharging means by contact of injector with patient body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/20Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M2005/206With automatic needle insertion
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/20Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M2005/2073Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically preventing premature release, e.g. by making use of a safety lock

Abstract

Automatic injector,It includes the main body (1) for being suitable for receiving reservoir (S),Reservoir (S) is comprising fluid product and including piston (P) and syringe needle (A),Such as pre-filled syringe,Automatic injector includes can be relative to the actuating sleeve (10) that main body (1) is moved between projecting positions and actuated position,In projecting positions,Actuating sleeve (10) is at least partly projected into main body (1) outside,In actuated position,Actuating sleeve (10) is moved axially into main body (1),Actuating sleeve (10) is positioned at the first projecting positions before automatic injector actuating,Actuating sleeve is located at the second projecting positions after automatic injector actuating,Actuating sleeve (10) pushes projecting positions to by spring (9),Automatic injector is included in using the dismountable the cover (20) being fixed on before automatic injector in main body (1),When dismountable the cover is fixed in main body (1),The active force that dismountable the cover (20) makes actuating sleeve (10) resist spring (9) moves axially a distance (d) with respect to the first projecting positions into main body (1),So that when dismountable the cover (20) is removed from main body (1),Spring (9) takes actuating sleeve to first projecting positions.

Description

Automatic injector
Technical field
The present invention relates to a kind of automatic injectors.
Background technology
Automatic injector is commonly known in the art.The main purpose of these devices is that realize will be in syringe Hold in automatic injection to patient body.Existing now makes syringe needle go deep into patient body and inject to be included in syringe automatically The various systems of fluid product.Automatic injector is more complicated device, in order to reliable, should meet a certain number of limitation items Part requirement.The fastness of device, it operability and it be also key factor to the ease of use of user.In addition, The major part of these automatic injectors is first use, and manufacture and assembly cost are also the factor that must take into consideration.
In the market there are many automatic injectors, but they all there are the shortcomings that certain amount.
Therefore, in order to avoid the unexpected automatic startup of automatic injector, such as during transport or storage, device should include Reliable locking member.Equally, when user is desirable for automatic injector, device does not answer accidental activation, but can only be Start when user really wishes, i.e., when it sticks on the body part for wishing implement injection.However, especially when use from When the personnel of dynamic syringe are aged or disableds, it may occur that user makes dress at the time of he is desirable for syringe Put situation about falling.It is desirable that in this case, automatic injector is not activated individually.Therefore, setting is reliable starts lock It is critically important to determine device.On the other hand, the use of automatic injector should not be too difficult, because this can prevent weak people from cannot make Use syringe.In addition, in order to avoid danger injured after device use, automatic injector should include needle safety apparatus, avoid Device still keeps exposed using rear syringe needle.The safety device obviously also should be reliable, and cannot easily discharge very much.Even In user's accidental activation automatic injector, for example, he before injection terminates from his body remove syringe it is too early when can also transport Row.
However, automatic injector just uses after the long period sometimes only after assembling, and therefore, different component parts, It is critically important especially to start lock and needle safety apparatus or even still keep reliability service after storage for a long period.This is just It is the target that the present invention answers this problem.
Document WO201375140, WO2013175142, WO2015075399, WO2012045833, FR2884722, WO9632974 and WO2012000832 all describes the device of the prior art.
The content of invention
The purpose of the present invention is to propose to a kind of automatic injector for not generating disadvantages mentioned above, which can meet not Same important requirement and restrictive condition, safely and reliably to use automatic injector.
The present invention also aims to provide a kind of automatic injector, the automatic injector is even after storage for a long period All using reliable, safety and risk of injury can be prevented, and the manufacture and assembling of the automatic injector are simple, cheap.
Therefore, it is an object of the present invention to a kind of automatic injector, including for receiving the main body of reservoir, the storage Device includes fluid product and including piston and syringe needle, such as pre-filled syringe, and the automatic injector includes can be with respect to institute The actuating sleeve that main body moves between projecting positions and actuated position is stated, in projecting positions, the actuating sleeve is at least partly It is projected into outside the main body, in actuated position, the actuating sleeve is moved axially into the main body, is activated in automatic injector The preceding actuating sleeve is located at the first projecting positions, and the actuating sleeve is located at the second projection position after automatic injector actuating It puts, the actuating sleeve pushes the projecting positions to by spring, and the automatic injector is included in using solid before automatic injector Fixed dismountable the cover on the body, it is described detachable when dismountable the cover is fixed on the body The cover relatively described first projecting positions of active force that the actuating sleeve is made to resist the spring it is axial into the main body A mobile distance so that when dismountable the cover is removed from the main body, the spring is by the cover band to described First projecting positions.
Advantageously, one in the actuating sleeve and the main body includes flexible pawl, when the actuating sleeve moves, The flexibility is grabbed suitable for relatively described actuating sleeve and/or relatively described main body be lateral or radial deformation, the actuating sleeve and institute Another stated in main body includes guide profile, and when the actuating sleeve moves, which coordinates with the flexible pawl.
Advantageously, when then the actuating sleeve is moved from its first projecting positions to its actuated position from its actuated position When returning to its second projecting positions, it is lateral and/or radially that the flexibility grabs relatively described actuating sleeve and/or relatively described main body Deformation.
Advantageously, the guide profile includes the initial trench at least partly limited by convex shoulder, when the actuating sleeve position When first projecting positions, the convex shoulder coordinates with the flexible pawl.
Advantageously, in first projecting positions, the active force of the spring is applied to the flexible pawl and the convex shoulder Between contact point on.
Advantageously, dismountable the cover includes fixed fixed component on the body.
Advantageously, the fixed component includes the air ring in fixed face, such as radially-inwardly protrusion, fixed face with it is described The complementary exterior section cooperation of main body, the exterior section of the complementation are generally the air ring of radially outward protrusion.
Advantageously, the fixed component includes two diameters relatively and surrounds the axially extending pawl of the main body, each Axial pawl includes a fixed face.
Advantageously, the actuating sleeve includes the contact end contacted for the body with user.
Advantageously, the main body includes the flexible pawl, and the actuating sleeve includes the guide profile.
As modification, the main body includes the guide profile, and the actuating sleeve includes the flexible pawl.
Description of the drawings
By reading referring to only be used as the detailed description of attached drawing progress that non-limiting example provides, of the invention this A little feature and advantage and other feature and advantage, which will be clearly shown, to be come, in attached drawing:
Fig. 1 a are that the automatic injector of an Advantageous embodiments according to the present invention is schematic before protective cover is removed Side view;
Fig. 1 b are the schematic side elevations from the partial cut of the automatic injector of Fig. 1 a in terms of other direction;
Fig. 1 c are the partial schematic cross-sectional views of the automatic injector of Fig. 1 a and 1b;
Fig. 1 d are the partial schematic diagrams of the thin portion of the cut-away portions of Fig. 1 b;
Fig. 2 a-2d be after protective cover is removed and automatic injector actuating before the figure similar with Fig. 1 a-1d respectively;
Fig. 3 a are the schematic diagrames of the thin portion compared with the proximal part of automatic injector removes front and back position with protective cover;
Fig. 3 b are from the figure similar with Fig. 3 a in terms of other direction.
Specific embodiment
In the following description, term " on ", " under ", "high", " low " are with reference to position shown in figure.Term " near ", " remote " syringe needle with reference to automatic injector.The longitudinal center axis X of term " axial direction " and " radial direction " with reference to shown on Fig. 1 c.
Automatic injector is described next, with reference to an Advantageous embodiments of automatic injector.However, it is noted that Automatic injector is complicated instrument, including multiple modules for being used to implement multiple functions.These various modules can divide mutually It opens and uses independently of each other, not necessarily combined with other modules, it especially can be with to that indicated in the drawings variform It is used in the automatic injector of shape.It is further noted that attached drawing is schematic diagram, it is not necessary to represent the composition portion of syringe The exact shape of part, and especially for clear purpose, it is not necessary in proportion.In addition, attached drawing is not required to show All constituent element of automatic injector, and element necessary to the operation to the present invention is only shown.Therefore, it is various supplement and/ Or the element and module of complementation can be incorporated into the automatic injector shown on attached drawing.
Automatic injector shown on attached drawing includes main body 1, and actuating sleeve 10 slides axially in main body, actuating sleeve Lower end 101 is used to contact with the patient body around injection zone.In the example shown on attached drawing, under automatic injector includes Portion main body 1a, intermediate host 1b and upper body 1c, they assemble the main body 1 to form automatic injector, on Fig. 1 a and 2a It is shown.In the following, term " main body " and reference numeral " 1 " will be used to representing the sub-body 1a and intermediate host 1b and The upper body 1c assembles the single main body to be formed.It is noted that main body 1 can be by any amount of main part shape Into, such as two parts, and the embodiment of attached drawing is not restricted there are three main part.
Reservoir S is inserted in the automatic injector.Reservoir S includes fluid product, and including piston P and syringe needle A.Piston P is suitable for moving in the reservoir S, to be passed through the syringe needle A injecting fluid products.This specification will be with reference to can To be that any kind of syringe S is described., it is more common that certainly, the term " syringe " in this specification enumerates Any kind of reservoir combined with syringe needle.Preferably, reservoir S is pre-filled syringe.
Automatic injector further includes automatic injection system, which especially includes piston rod 5, and piston rod is used for Coordinate with piston P, so that piston moves in reservoir S, to be passed through syringe needle A distribution fluid products.In general, the piston rod 5 The dispensing position that spring 8 pushes piston rod to is injected, and piston rod is maintained at by appropriate injection lock before actuating Resting position.Describing some in document WO2013175148 and the PCT/FR2015/050940 of co-pending application has The example of the injection lock of profit.As can schematically see very much on Fig. 1 c and 2c, injection lock can include It is at least one and preferably three locked rings 7 are maintained at the locking member 6 of latched position.The piston rod 5 can include receiving The radial groove of the movable locking member between locked and unlocked positions.The locking member is preferably substantially ball Shape, such as some beads.Advantageously, the bead is radially outward pushed by the piston rod 5, and passes through the locking ring 7 It is maintained at latched position.The locking ring 7 can relatively described piston rod 5 axially upwardly moved between locked position and unlocked position Dynamic, in locked position, the bead is maintained at latched position by piston rod, and in unlocked position, the bead is released, to because This unlocks the injection lock, enables the injection spring 8 that the piston rod 5 to be made to be moved to its injection position.Favorably Ground, when the syringe needle A of syringe S enters in the body of user, locking ring 7 axially upwardly moves, and effect is from bead Latched position discharges bead, then bead moves radially outward.Then piston rod 5 is no longer kept by bead, therefore piston rod is to lower axle To movement, to realize the injection of product.
Automatic injector may also include vision, sound and/or haptic indication device, so as to especially by audible sound Sound indicates that he can remove automatic injection from injection position by vibration and/or by vision and/or haptic indication to user Device.Especially, instruction device can include one or more indicator elments, and indicator elment on the one hand can be by main body 1 Enough displays in one or more windows 11, which provide, to be visually indicated, and on the other hand provide sound and/or haptic indication.
Actuating sleeve 10 can be that any kind of spring 9 pushes its projecting positions to.9 one side of spring and the cause Moving sleeve 10 coordinates, and on the other hand the part 12 with being fixed together with main body 1 coordinates.Before actuating, actuating sleeve 10 is located at It surrounds the first projecting positions of syringe needle A, as shown in figs. 2 a-2 c.During actuating, actuating sleeve 10 is in main body 1 to actuated position It slides, so that exposed needle A can simultaneously be punctured, then injecting fluid product.After injection, when user removes certainly from injection position During dynamic syringe, actuating sleeve 10 is returned to using the second projecting positions terminated, and in second projecting positions, it surrounds needle again Head arrangement, to avoid any danger stabbed by the syringe needle A.It is noted that the first and second projections of actuating sleeve 10 Position can be different position or identical position.
According to the present invention, dismountable the cover 20 that the automatic injector person of including the use of should remove before actuating.
Before automatic injector is used, the syringe needle A of syringe S is advantageously subjected to protect generally made of elastic material The protection of cover 2, the end of syringe needle are punctured in protective cover.In this case, removing dismountable the cover 20 advantageously makes institute Protective cover 2 is stated to remove from syringe needle A.
The cover 20 includes the fixed component 21 being fixed on the proximal part of the main body 1.Advantageously, the fixation Component 21 includes fixed face 25, the air ring such as radially protruded, fixed face and the complementary external portion of the main body 1 Divide 15 cooperations, the exterior section of the complementation is generally the air ring of outward radial protrusion.Therefore, the air ring 15 and 25 is matched Dismountable the cover 20 is maintained in the main body 1, and user should apply predetermined axial force by conjunction, so as to The cover 20 can be made to be detached from the main body 1.
Advantageously, the fixed component 21 includes two diameters relatively and surrounds the 1 axially extending pawl of main body, often A axial direction pawl includes a fixed face 25, as shown in Fig. 1 a and 3b.
Actuating sleeve 10 includes guide profile, which includes multiple grooves, especially initial trench 100, main body 1 Including flexible pawl 110, when actuating sleeve is moved when automatic injector is activated relative to main body 1, flexible pawl and actuating sleeve 10 Groove cooperation.This cooperation between the flexible pawl 110 of main body 1 and the guide profile of actuating sleeve 10 can realize that actuating is opened The startup locking and the locking of home of beginning is equivalent to the second projecting positions of the actuating sleeve.
As described in document WO2013175140, WO2013175142 and WO2015075399, flexible pawl 110 is in the guiding It is lateral and/or move radially in type face, to ensure the startup of automatic injector and then lock, therefore the reliability service of the flexibility pawl It is critically important.However, before actuating, and during no dismountable the cover 20, spring 9 pushes actuating sleeve to its first projection Position, therefore, the head of flexible pawl 110 is at the contact point C between the flexible head of pawl 110 and the convex shoulder 13 of main body 1 Under the stress of the spring, the bottom wall of the guide profile is limited, particularly limits initial trench 100.Contact point C exists It can see on Fig. 2 d.
However, the active force that spring 9 applies at contact point C has the tendency that being stretched by flexible 110 axial deformation of pawl.This Kind tensioning may change the mechanical strength property of flexible pawl 110, therefore reduce its performance, in needle safety at the end of particularly activating The intensity of position.The time for being tensioned holding is longer, and the danger of destruction is bigger.Therefore, the long-time of automatic injector before use Storage increases this danger.
According to the present invention, the fixation of dismountable the cover 20 on the body 1 causes actuating sleeve 10 axially upwardly to move, from And make the flexible pawl from the stress release for being subjected to spring 9.
More precisely, when dismountable the cover 20 is fixed on the body 1, actuating sleeve 10 axially upwardly moves (i.e. To the direction of the distal portions of main body 1) a distance d, mild compression spring 9.As on Fig. 1 d it can be seen that, then main body 1 It is not in contact between the head of convex shoulder 13 and flexible pawl 110, this axial stress that flexible pawl is just made to apply from spring 9 releases Come.Therefore, the fixation of dismountable the cover 20 on the body 1 should be more stronger than the active force that spring 9 is applied on actuating sleeve 10. In fact, when being not in contact between flexible pawl 110 and the convex shoulder 13 of main body 1, the active force of spring 9 is applied to removably In the cover 20, actuating sleeve is maintained at the position for the distance d that is staggered upwards by dismountable the cover.Therefore, the active force is more accurate Ground, which is applied to, fixes dismountable the cover 20 in fixed component on the body 1, i.e., in the example shown, fixes in fig 3b On the air ring 15 and 25 that can see.Therefore user should be more than spring 9 application active force axial force axially downwardly Dismountable the cover 20 is pulled down, so as to remove the cover from the main body 1.
When user removes dismountable the cover 20, spring 9 will make the actuating sleeve move axially downwards institute Distance d is stated, brings it to the first projecting positions, in first projecting positions, as can be seen on Fig. 2 d, the head of flexible pawl 110 Portion is contacted with the convex shoulder 13 of main body 1.
Fig. 3 a and 3b shows do not have the position of the cover with right side with position of the left side with the cover in figure in two different directions It puts and compares, when dismountable the cover 20 is fixed on the body 1, the upward displacement distance d of actuating sleeve 10.
Therefore, two locks of actuating sleeve, that is, the locking lock spy started after lock and actuating before activating It is not effectively and reliable, while mold and assembling are firm, easy and therefore cheap.Particularly, lock only includes two components, Actuating sleeve 10 and main body 1.
Of course, it is possible to change the shape of guide profile and flexible pawl with desired feature as needed.
It is noted that above-mentioned component can be made of opposite mode, i.e., main body 1 can include guide profile, and outstanding It is initial trench 100, and actuating sleeve 10 can include flexible pawl 110.
Especially, the present invention is applied to the device that uses for the treatment of autoimmune disease, such as rheumatoid arthritis, a variety of Sclerosis, Crow grace type disease, for anticancer therapy, for antiviral therapy, such as hepatitis, for treating diabetes, for poor Blood is treated or is broken out for allergy and treats, such as in the case of anaphylactic shock.
Although with reference to an Advantageous embodiments, invention has been described, certainly, those skilled in the art can To be carry out various modifications to it, and without departing from the scope of the present invention defined in the appended claims.

Claims (11)

1. a kind of automatic injector, including suitable for receiving the main body (1) of reservoir (S), the reservoir (S) is produced comprising fluid Product and including piston (P) and syringe needle (A), such as pre-filled syringe, the automatic injector includes being capable of relatively described main body (1) actuating sleeve (10) moved between projecting positions and actuated position, in projecting positions, the actuating sleeve (10) is at least It is partially project into the main body (1) outside, in actuated position, the actuating sleeve (10) moves axially into the main body (1), The actuating sleeve (10) is positioned at the first projecting positions before automatic injector actuating, the actuating set after automatic injector actuating Cylinder is located at the second projecting positions, and the actuating sleeve (10) pushes the projecting positions, the automatic injector packet to by spring (9) The dismountable the cover (20) being fixed on before automatic injector is used in the main body (1) is included,
It is characterized in that, when being fixed in the main body (1), dismountable the cover (20) and the actuating sleeve (10) Cooperation so that the actuating sleeve resists relatively described first projecting positions of active force of the spring (9) to the main body (1) Interior one distance (d) of axial movement so that when dismountable the cover (20) is removed from the main body (1), the spring (9) The actuating sleeve (10) is shifted onto in first projecting positions.
2. automatic injector according to claim 1, wherein, one in the actuating sleeve (10) and the main body (1) It is a including flexible pawl (110), when the actuating sleeve (10) is mobile, the flexibility pawl is suitable for relatively described actuating sleeve (10) And/or relatively described main body (1) is lateral and/or radial deformation, another in the actuating sleeve (10) and the main body (1) Including guide profile, when the actuating sleeve (10) is mobile, the guide profile coordinates with the flexible pawl (110).
3. automatic injector according to claim 2, wherein, when the actuating sleeve (10) from its first projecting positions to When the movement of its actuated position returns to its second projecting positions from its actuated position then, described flexibility pawl (110) relatively described cause Moving sleeve (10) and/or relatively described main body (1) be lateral and/or radial deformation.
4. the automatic injector according to Claims 2 or 3, wherein, the guide profile is included at least partly by convex shoulder (13) initial trench (100) limited, when the actuating sleeve (10) is positioned at first projecting positions, the convex shoulder and institute State flexible pawl (110) cooperation.
5. automatic injector according to claim 4, wherein, in first projecting positions, the flexibility pawl (110) with The convex shoulder (13) coordinates at contact point (C) so that the spring (9) axially pushes the flexible pawl (110).
6. automatic injector according to any one of the preceding claims, wherein, dismountable the cover (20) includes The fixed component (21) being fixed in the main body (1).
7. automatic injector according to claim 6, wherein, the fixed component (21) includes fixed face (25), such as The radially-inwardly air ring of protrusion, fixed face and the complementary exterior section (15) of the main body (1) coordinate, outside the complementation Portion part is generally the air ring of radially outward protrusion.
8. automatic injector according to claim 7, wherein, the fixed component (21) it is opposite including two diameters and Around the main body (1) axially extending pawl, each axial direction pawl includes a fixed face (25).
9. automatic injector according to any one of the preceding claims, wherein, the actuating sleeve (10) is including being used for The contact end (101) contacted with the body of user.
10. automatic injector according to any one of the preceding claims, wherein, the main body (1) includes the flexibility Pawl (110), the actuating sleeve (10) include the guide profile.
11. according to the automatic injector described in any one of claim 1-9, wherein, the main body (1) includes the leading type Face, the actuating sleeve (10) include the flexible pawl (110).
CN201680055020.6A 2015-09-22 2016-09-20 Automatic injector Active CN108136120B (en)

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FR1558927A FR3041262B1 (en) 2015-09-22 2015-09-22 AUTOINJECTOR
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PCT/FR2016/052384 WO2017051113A1 (en) 2015-09-22 2016-09-20 Auto-injector

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EP3352819A1 (en) 2018-08-01
EP3352819B1 (en) 2021-02-03
US11305062B2 (en) 2022-04-19
FR3041262B1 (en) 2020-11-20
WO2017051113A1 (en) 2017-03-30
CN108136120B (en) 2021-06-15
US20180264196A1 (en) 2018-09-20
FR3041262A1 (en) 2017-03-24
JP6861204B2 (en) 2021-04-21
JP2018528016A (en) 2018-09-27

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