CN108133744A - Health detection method and its system based on intestinal flora detection - Google Patents
Health detection method and its system based on intestinal flora detection Download PDFInfo
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- CN108133744A CN108133744A CN201711422366.8A CN201711422366A CN108133744A CN 108133744 A CN108133744 A CN 108133744A CN 201711422366 A CN201711422366 A CN 201711422366A CN 108133744 A CN108133744 A CN 108133744A
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- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
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- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
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- G—PHYSICS
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Abstract
The invention discloses a kind of health detection method and system based on intestinal flora detection, wherein method includes the following steps：Human excrement and urine's sample is detected, obtains the intestinal flora parameter of user, if the intestinal flora parameter includes intestinal flora ratio and dry strain content；Diet guide information is sent to user according to the intestinal flora parameter of user.By the intestinal flora parameter for obtaining user, and diet guide information is sent to user according to the intestinal flora parameter of the user, user to be instructed to take in corresponding probiotics, so as to targetedly improve to the health status of user, it realizes the discovery as early as possible to potential inferior health or morbid state and appropriate disposition, reduces the risk that health status further deteriorates.
Description
Technical field
The present invention relates to health detection field, more particularly to a kind of health detection based on intestinal flora detection
Method and its system.
Background technology
With the improvement of living standards, people increasingly pay close attention to the health status of itself, it is a variety of right also to occur in the market
The system that health is managed and instructs, but it is existing it is health management system arranged in be by directly can be from body surface mostly
The characteristic parameters such as body temperature, blood pressure, the fat content of measurement are monitored and instruct to the health condition of human body, though with certain
Effect is instructed, but is not obvious, be primarily due to user and does not know about the reason of generating health problem, cannot also carry out needle
Improvement to property.And with the continuous quickening of rhythm of life, irregular, more and more groups' appearance of the eating habit of people
Gastrointestinal problems, especially based on city white collar and light physical labor and mental labour, are mainly reflected in diarrhea, flatulence etc.
Malaise symptoms；And there is the reason of this symptom and be primarily due to：Not only live probiotics in the gastrointestinal tract of human body, also occupies
The neutral bacterium such as stomach Helicobacter pylori, Escherichia coli, Pseudomonas aeruginosa and harmful bacteria are lived, they are maintained in the gastrointestinal tract of human body
Certain balance, remains the health of human body, and works as high in fat, high protein in human body and takes in excessively, food fiber was taken in
It is few, it is easy to the colony balance in human body intestinal canal to be caused to be broken, if when the probiotics quantity in gastrointestinal tract is reduced to centainly
During degree, the harmful bacteria in enteron aisle will stir up trouble, and the gastrointestinal tract immunity of human body will decline, and go out so as to cause human body
Existing above-mentioned gastrointestinal problems, and sub-health state is in when allowing for human body under the torment for a long time in this problem, even
Generate disease.Lack in the prior art and effectively human health status is directed to according to the actual conditions of human body intestinal canal flora
The method that property is improved.
Invention content
In view of this, the present invention provides a kind of health detection method and its system based on intestinal flora detection, can
Diet guide information is sent to user with the intestinal flora parameter according to user, with instruct user carry out corresponding dietetic nutrition and
The adjustment of living habit, so as to improve the health status of user.
The health detection method based on intestinal flora detection of the present invention, includes the following steps：
Human excrement and urine's sample is detected, obtains the intestinal flora parameter of user, intestinal flora parameter includes intestinal flora ratio
If with dry strain content；
Diet guide information is sent to user according to the intestinal flora parameter of user.
Further, human excrement and urine's sample is detected, the intestinal flora parameter of user is obtained, includes the following steps：
By human excrement and urine's sample of gram stain microscopy Preliminary detection user, intestinal flora ratio is determined；
If detect dry strain content in human excrement and urine's sample.
Further, wherein, if in detection human excrement and urine's sample dry strain content be specially detect it is double in human excrement and urine's sample
Discrimination bacillus, Lactobacillus casei kind, lactobacillus acidophilus, enterococcus, enterobacteria and Eubacterium content.
Further, diet guide information is sent to user according to the intestinal flora parameter of user, including：
The intestinal flora parameter detected and pre-stored flora ratio correspondence and strain data sample are carried out
It compares, to determine intestinal flora index out of proportion in user's body；
It is sent and the corresponding diet guide information of intestinal flora index out of proportion to user.
Further, wherein, flora ratio correspondence is, when G+ bacillus>90% be ratio normal type, G+ bacillus 10%~
90% be ratio osculant, G+ bacillus<10% is type out of proportion.
Further, according to the human parameters of user after user sends diet guide information, method further includes：
It obtains after user receives diet guide information and selected the probiotic products and content taken in daily in N days；
Human excrement and urine's sample of user is detected after N days again, obtains current intestinal flora parameter；
Intestinal flora parameter is detected before diet guide information being received compared with current intestinal flora parameter pair, and to
User, which sends intestinal flora, improves information.
The invention also discloses it is a kind of based on intestinal flora detection human health detection system, including：
First acquisition module, for obtaining the intestinal flora parameter of user, intestinal flora parameter includes intestinal flora ratio
If with dry strain content；
Sending module starts diet guide information for the intestinal flora parameter of basis to user.
Further, sending module includes：
First comparing unit, for by intestinal flora parameter and pre-stored flora ratio correspondence and strain data
Sample is compared, to determine intestinal flora index out of proportion in user's body；
First transmitting element is believed for being sent to user with the corresponding diet guide of intestinal flora index out of proportion
Breath.
Further, system further includes：
Second acquisition module selected the prebiotic of intake daily for obtaining after user receives diet guide information in N days
Bacterium product and content；
Second comparing unit, for detecting intestinal flora parameter with being obtained after N days before receiving diet guide information
The intestinal flora parameter taken compared to pair；
Intestinal flora improvement information after sending module can also compare the second comparing unit is sent to user.
Further, the first acquisition module includes：
First detection device, for using the intestinal flora ratio of gram stain microscopy equipment detection user；
Second detection device, for using the content of strain in PCR detection devices detection user's human excrement and urine's sample.
Compared with prior art, the invention has the advantages that：The human body based on intestinal flora detection of the present invention
Health detecting method and its system, by obtaining the intestinal flora parameter of user, and according to the intestinal flora parameter of the user to
User sends diet guide information, user to be instructed to take in corresponding probiotics, so as to targetedly to the healthy shape of user
State is improved, and realizes discovery as early as possible and appropriate disposition to potential inferior health or morbid state, reduces health status into one
Walk the risk deteriorated.
Description of the drawings
The invention will be further described with reference to the accompanying drawings and examples.
Fig. 1 is the step flow chart of the embodiment one of the health detecting method of the present invention；
Fig. 2 is the step flow chart of the embodiment two of the health detecting method of the present invention；
Fig. 3 is the step flow chart of the embodiment three of the health detecting method of the present invention；
Fig. 4 is the schematic diagram of the health detecting system of the present invention.
Specific embodiment
The technical solution in the embodiment of the present invention is carried out below in conjunction with the attached drawing in the embodiment of the present invention clear, complete
Description, it is clear that described embodiment be only the present invention part of the embodiment, instead of all the embodiments.It is based on
The embodiment of the present invention, the every other reality that those of ordinary skill in the art are obtained without making creative work
Example is applied, shall fall within the protection scope of the present invention.In addition, the technical solution between each embodiment can be combined with each other, but must
Must can be implemented as basis with those of ordinary skill in the art, when the combination of technical solution occurs conflicting or can not realize
When will be understood that the combination of this technical solution is not present, also not the present invention claims protection domain in.
The present invention proposes a kind of health detection method based on intestinal flora detection, it should be noted that the present invention
Personal computer, personal digital assistant (PDA), Intelligent mobile equipment can be combined in each embodiment (including mobile phone, movement
Computer, tablet computer etc.) etc. equipment use, health management service device, health management service device memory storage flora ratio can be set
Correspondence and strain data sample, and data processing can be carried out and with mobile equipment into row data communication, it realizes to single
Or the health control to multiple users simultaneously.
Embodiment one
As shown in Figure 1, in the present embodiment, detection method includes the following steps for health：
Step S11, human excrement and urine's sample is detected, obtains the intestinal flora parameter of user, intestinal flora parameter includes enteron aisle
If flora ratio and dry strain content；Specifically, existing detection can be passed through by taking human excrement and urine's sample of specific user
If method measures the intestinal flora proportionate relationship in its fecal sample and dry strain content, wherein, intestinal flora ratio
Relationship is mainly embodied by the proportionate relationship of gram-positive bacteria and Gram-negative bacteria, and the content of specific strain can detect more
The content of common probiotics and the content of common pathogen are planted, concretely Bifidobacterium, Lactobacillus casei kind, acidophilus breast bar
Bacterium, enterococcus, enterobacteria and Eubacterium content；In addition, specific detection method can add bacterium colony by traditional Bacteria Culture
Counting method or molecular biology quantitative analysis method；
Step S12, diet guide information is sent to user according to the intestinal flora parameter of user；In the enteron aisle for obtaining user
Flora parameter rear line sends detected intestinal flora parameter, including intestinal flora ratio and strain content, and synchronizes
To user's transmission and the detected corresponding diet guide information of intestinal flora parameter, user is reasonably instructed to currently lacking
Few probiotics strain is taken in by way of diet, to adjust the flora ratio in user's human body intestinal canal.
The health detecting method of the present embodiment, by obtaining the intestinal flora parameter of user, and according to the enteron aisle of the user
Flora parameter sends diet guide information to user, user to be instructed to take in corresponding probiotics, so as to targetedly to
The health status at family is improved, and realizes discovery as early as possible and appropriate disposition to potential inferior health or morbid state, is reduced strong
The risk that health situation further deteriorates.
Embodiment two
The health detecting method of the present embodiment is on the basis of above-described embodiment one, and further more detailed introduction is originally
The technical solution of invention.As shown in Fig. 2, detection method includes the following steps for health in the present embodiment：
S21, human excrement and urine's sample by gram stain microscopy Preliminary detection user, determine intestinal flora ratio.
Specifically, using the fecal sample of direct smear Microscopical Method For Detection detection user, 1/3rd in normal fecal stools sample
Weight is bacterium, and the ratio that each bacterium accounts for is also different, and it is out of proportion that this method mainly observation different strain whether there is.Just
Grain-positive bacillus has comparative advantage, secondly gram negative bacilli or coccus, a small amount of yeast fungus in normal excrement.When human body by
In system infections, using a large amount of antibacterials, the bacterium in the range of antimicrobial spectrum is greatly suppressed and other flora raised growths,
The imbalance of body microecological balance can often occur while infection control, and faecal microbiota variation is the sensitive mark of microbial state treatment
Will.It is any strain that although method of direct smear, which cannot directly be told, when flora changes, from Grain stain and form
Feature can make preliminary judgement.During detection, fresh excreta thick smear is taken, Gram dyeing counts.
If dry strain content in S22, detection human excrement and urine's sample.
I.e. using the 16SrDNA for enterobacteriaceae, using universal primer PCR and specific probe and new-generation sequencing sequence
Row, detect human excrement and urine's sample in Bifidobacterium, Lactobacillus casei kind, lactobacillus acidophilus, enterococcus, enterobacteria and Eubacterium and
Its content.Specifically, using the fecal sample of PCR detection users, i.e., directly detect clinical samples by analyzing microbial nucleic acids
The method of middle bacterium, the analysis of the crystallinity that the DNA of extraction bacterium comes from sample qualitatively and quantitatively.Expanded with specific PCR primers
Increase Bifidobacterium, Lactobacillus casei, lactobacillus acidophilus, enterococcus, enterobacteria, Eubacterium 16SrDNA sequence fragment；It will
16SrDNA segments are inserted into carrier T, are transferred in competent cell made from DH5 α Escherichia coli, are chosen by the screening of blue hickie and contained
There is the thalline of Insert Fragment, then confirm that Insert Fragment is the special 16srDNA segments of each Pseudomonas by sequencing；Single bacterium colony is for a large amount of
Culture, then extract the standard items DNA that Plasmid DNA obtains each Pseudomonas.The mark being pumped finally by UV detector measure
Quasi- product DNA concentration, then it is diluted to a 109copies/uL；6 kinds of Pseudomonas standard items obtained are set according to table is uniformly distributed
The scheme mixing of meter, is utilized respectively 16SrDNA universal primers and is expanded, using PCR product as template, probe hybrid plan is same
The parting detection of Shi Jinhang LDR and LCR, finally obtain fluorescence signal by sequenator, using template concentrations ratio as abscissa, signal ratio
For ordinate, linear regression analysis is done, obtains standard curve；The detection of sample is carried out at the same time with standard items, last reference standard
Curve reads or calculates the relative concentration of above-mentioned bacterium.
Wherein, PCR is beforehand through to the positive template for inhibiting the different extension rates of copy number, makes standard curve,
The contents of beneficial bacteria of intestinal tract and pathogenic bacteria is stored as data sample, sample by with large database concept data sample standard curve into
Row relatively can obtain quantitative result, to determine the content of the beneficial bacteria of intestinal tract of user and pathogenic bacteria.
S23, by the intestinal flora parameter detected and pre-stored flora ratio correspondence and strain data sample
It is compared, to determine intestinal flora index out of proportion in user's body；Wherein, flora ratio correspondence is, when G+ bacillus>
90% be ratio normal type, G+ bacillus 10%~90% be ratio osculant, G+ bacillus<10% is type out of proportion；In addition, intestines
Flora index out of proportion in road can be designed according to flora ratio correspondence and strain content, can set one to ten grades, than
Example normal type is level-one, and type out of proportion is ten grades, and user determines certainly according to the index out of proportion (i.e. series) received
The situation of the present intestinal flora of body.
S24, it is sent and the corresponding diet guide information of intestinal flora index out of proportion to user.That is, correspondence is each
Grade intestinal flora index out of proportion simultaneously summarizes detected strain content correspondence and is designed with diet guide information, can instruct to use
Family improves intestinal flora by diet.
Embodiment three
The health detecting method of the present embodiment is on the basis of above-described embodiment one, and further more detailed introduction is originally
The technical solution of invention.As shown in figure 3, detection method includes the following steps for health in the present embodiment：
S31, human excrement and urine's sample by gram stain microscopy Preliminary detection user, determine intestinal flora ratio.
Specifically, using the fecal sample of direct smear Microscopical Method For Detection detection user, 1/3rd in normal fecal stools sample
Weight is bacterium, and the ratio that each bacterium accounts for is also different, and it is out of proportion that this method mainly observation different strain whether there is.Just
Grain-positive bacillus has comparative advantage, secondly gram negative bacilli or coccus, a small amount of yeast fungus in normal excrement.When human body by
In system infections, using a large amount of antibacterials, the bacterium in the range of antimicrobial spectrum is greatly suppressed and other flora raised growths,
The imbalance of body microecological balance can often occur while infection control, and faecal microbiota variation is the sensitive mark of microbial state treatment
Will.It is any strain that although method of direct smear, which cannot directly be told, when flora changes, from Grain stain and form
Feature can make preliminary judgement.During detection, fresh excreta thick smear is taken, Gram dyeing counts.
If dry strain content in S32, detection human excrement and urine's sample.
I.e. using the 16SrDNA for enterobacteriaceae, using universal primer PCR and specific probe and new-generation sequencing sequence
Row, detect human excrement and urine's sample in Bifidobacterium, Lactobacillus casei kind, lactobacillus acidophilus, enterococcus, enterobacteria and Eubacterium and
Its content.Specifically, using the fecal sample of PCR detection users, i.e., directly detect clinical samples by analyzing microbial nucleic acids
The method of middle bacterium, the analysis of the crystallinity that the DNA of extraction bacterium comes from sample qualitatively and quantitatively.Expanded with specific PCR primers
Increase Bifidobacterium, Lactobacillus casei, lactobacillus acidophilus, enterococcus, enterobacteria, Eubacterium 16SrDNA sequence fragment；It will
16SrDNA segments are inserted into carrier T, are transferred in competent cell made from DH5 α Escherichia coli, are chosen by the screening of blue hickie and contained
There is the thalline of Insert Fragment, then confirm that Insert Fragment is the special 16srDNA segments of each Pseudomonas by sequencing；Single bacterium colony is for a large amount of
Culture, then extract the standard items DNA that Plasmid DNA obtains each Pseudomonas.The mark being pumped finally by UV detector measure
Quasi- product DNA concentration, then it is diluted to a 109copies/uL；6 kinds of Pseudomonas standard items obtained are set according to table is uniformly distributed
The scheme mixing of meter, is utilized respectively 16SrDNA universal primers and is expanded, using PCR product as template, probe hybrid plan is same
The parting detection of Shi Jinhang LDR and LCR, finally obtain fluorescence signal by sequenator, using template concentrations ratio as abscissa, signal ratio
For ordinate, linear regression analysis is done, obtains standard curve；The detection of sample is carried out at the same time with standard items, last reference standard
Curve reads or calculates the relative concentration of above-mentioned bacterium.
Wherein, PCR is beforehand through to the positive template for inhibiting the different extension rates of copy number, makes standard curve,
The contents of beneficial bacteria of intestinal tract and pathogenic bacteria is stored as data sample, sample by with large database concept data sample standard curve into
Row relatively can obtain quantitative result, to determine the content of the beneficial bacteria of intestinal tract of user and pathogenic bacteria.
S33, by the intestinal flora parameter detected and pre-stored flora ratio correspondence and strain data sample
It is compared, to determine intestinal flora index out of proportion in user's body；Wherein, flora ratio correspondence is, when G+ bacillus>
90% be ratio normal type, G+ bacillus 10%~90% be ratio osculant, G+ bacillus<10% is type out of proportion；In addition, intestines
Flora index out of proportion in road can be designed according to flora ratio correspondence and strain content, can set one to ten grades, than
Example normal type is level-one, and type out of proportion is ten grades, and user determines certainly according to the index out of proportion (i.e. series) received
The situation of the present intestinal flora of body.
S34, it is sent and the corresponding diet guide information of intestinal flora index out of proportion to user.That is, correspondence is each
Grade intestinal flora index out of proportion simultaneously summarizes detected strain content correspondence and is designed with diet guide information, can instruct to use
Family improves intestinal flora by diet.
S35, the probiotic products and content taken in were selected daily in N days after obtaining user's reception diet guide information.
After user receives diet guide information, corresponding probiotic products can be taken according to the selection of diet guide information in N days,
To supplement the probiotics strain lacked in vivo, such as Bifidobacterium, Lactobacillus casei kind, lactobacillus acidophilus, this part is obtained
Data improve situation in order to calculate the intestinal flora of user.Wherein, N is more than or equal to 7 days.
Human excrement and urine's sample of user is detected after S36, N days again, obtains current intestinal flora parameter；I.e. repeat again into
Row step S31 and S32.
S37, intestinal flora parameter is detected before diet guide information being received compared with current intestinal flora parameter pair,
And send intestinal flora improvement information to user；A process for improving evaluation is formed, fecal sample will be detected finally twice
The intestinal flora parameter obtained is compared, and improves situation clearly to assess the intestinal flora of user.
The invention also discloses a kind of human health detection system based on intestinal flora detection, as shown in figure 4, disclosing
A kind of specific embodiment of system, in this embodiment, detecting system includes：First acquisition module, for obtaining the intestines of user
Road flora parameter, if intestinal flora parameter includes intestinal flora ratio and dry strain content；
Sending module starts diet guide information for the intestinal flora parameter of basis to user.
In the present embodiment, sending module includes：
First comparing unit, for by intestinal flora parameter and pre-stored flora ratio correspondence and strain data
Sample is compared, to determine intestinal flora index out of proportion in user's body；
First transmitting element is believed for being sent to user with the corresponding diet guide of intestinal flora index out of proportion
Breath.
In the present embodiment, system further includes：
Second acquisition module selected the prebiotic of intake daily for obtaining after user receives diet guide information in N days
Bacterium product and content；
Second comparing unit, for detecting intestinal flora parameter with being obtained after N days before receiving diet guide information
The intestinal flora parameter taken compared to pair；
Intestinal flora improvement information after sending module can also compare the second comparing unit is sent to user.
In the present embodiment, the first acquisition module includes：
First detection device, for using the intestinal flora ratio of gram stain microscopy equipment detection user；
Second detection device, for using the content of strain in PCR detection devices detection user's human excrement and urine's sample.
The health detecting system of the present embodiment, by using above-mentioned module realize to user send diet guide information, with
The realization mechanism of the health status of user is improved, it is identical with the realization mechanism of the health detecting method of the embodiment in above-mentioned Fig. 3,
It can refer to the specific record of above-mentioned embodiment illustrated in fig. 3 in detail, details are not described herein.
Finally illustrate, the above embodiments are merely illustrative of the technical solutions of the present invention and it is unrestricted, although with reference to compared with
The present invention is described in detail in good embodiment, it will be understood by those of ordinary skill in the art that, it can be to the skill of the present invention
Art scheme is modified or replaced equivalently, and without departing from the objective and range of technical solution of the present invention, should all be covered at this
In the right of invention.
Claims (10)
1. a kind of health detection method based on intestinal flora detection, it is characterised in that：Include the following steps：
Human excrement and urine's sample is detected, obtains the intestinal flora parameter of user, the intestinal flora parameter includes intestinal flora ratio
If with dry strain content；
Diet guide information is sent to user according to the intestinal flora parameter of user.
2. according to the method described in claim 1, it is characterized in that：Human excrement and urine's sample is detected, obtains the intestinal flora of user
Parameter includes the following steps：
By human excrement and urine's sample of gram stain microscopy Preliminary detection user, intestinal flora ratio is determined；
If detect dry strain content in human excrement and urine's sample.
3. according to the method described in claim 2, it is characterized in that：Wherein, if detecting dry strain content in human excrement and urine's sample
Specially detect Bifidobacterium, Lactobacillus casei kind, lactobacillus acidophilus, enterococcus, enterobacteria and true bar in human excrement and urine's sample
The content of bacterium.
4. according to the method described in claim 2, it is characterized in that：Diet is sent to user according to the intestinal flora parameter of user
Tutorial message, including：
The intestinal flora parameter detected and pre-stored flora ratio correspondence and strain data sample are compared,
To determine intestinal flora index out of proportion in user's body；
It is sent and the corresponding diet guide information of intestinal flora index out of proportion to the user.
5. according to the method described in claim 4, it is characterized in that：Wherein, the flora ratio correspondence is, when G+ bacillus
>90% be ratio normal type, G+ bacillus 10%~90% be ratio osculant, G+ bacillus<10% is type out of proportion.
6. according to the method described in claim 2, it is characterized in that：Diet guide is sent to user according to the human parameters of user
After information, the method further includes：
User is obtained according to the probiotic products and content for selecting intake after the diet guide information daily in N days；
Human excrement and urine's sample of user is detected after N days again, obtains current intestinal flora parameter；
Intestinal flora parameter is detected before diet guide information being received compared with current intestinal flora parameter pair, and to user
Sending intestinal flora improves information.
7. a kind of human health detection system based on intestinal flora detection, it is characterised in that：Including：
First acquisition module, for obtaining the intestinal flora parameter of user, the intestinal flora parameter includes intestinal flora ratio
If with dry strain content；
Sending module, for starting diet guide information to the user according to the intestinal flora parameter.
8. system according to claim 7, it is characterised in that：The sending module includes：
First comparing unit, for by the intestinal flora parameter and pre-stored flora ratio correspondence and strain data
Sample is compared, to determine intestinal flora index out of proportion in user's body；
First transmitting element is believed for being sent to the user with the corresponding diet guide of intestinal flora index out of proportion
Breath.
9. system according to claim 7, it is characterised in that：The system also includes：
Second acquisition module, it is prebiotic according to selecting to take in daily in N days after the diet guide information for obtaining user
Bacterium product and content；
Second comparing unit, for will receive detect before diet guide information behind intestinal flora parameter and N days acquired in
Intestinal flora parameter compared to pair；
Intestinal flora improvement information after the sending module can also compare the second comparing unit is sent to user.
10. system according to claim 7, it is characterised in that：First acquisition module includes：
First detection device, for detecting the intestinal flora ratio of the user using gram stain microscopy equipment；
Second detection device, for detecting the content of strain in the user human excrement and urine sample using PCR detection devices.
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Cited By (7)
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| CN110060778A (en) * | 2019-04-23 | 2019-07-26 | 完美(上海)健康科技有限公司 | Using intestinal flora as the health management scheme of target spot |
| CN110718271A (en) * | 2019-09-25 | 2020-01-21 | 君维安(武汉)生命科技有限公司 | Probiotic formula for inhibiting colorectal cancer pathogenic bacteria and screening method thereof |
| CN111139180A (en) * | 2020-01-07 | 2020-05-12 | 山东大学齐鲁医院(青岛) | Culture protection system of intestinal flora |
| WO2020202738A1 (en) * | 2019-03-29 | 2020-10-08 | コニカミノルタ株式会社 | Intestinal flora analysis system, information processor, and information processing method and program |
| JP2020201972A (en) * | 2019-04-16 | 2020-12-17 | 株式会社電通 | Ped food recommendation device, pet food recommendation method, supplement recommendation device, supplement recommendation method, intestinal age calculation formula determination method and intestinal age calculation method |
| CN112712856A (en) * | 2020-12-25 | 2021-04-27 | 北京群峰纳源健康科技有限公司 | Method for analyzing dietary structure based on intestinal flora |
| CN112992351A (en) * | 2021-03-09 | 2021-06-18 | 广西爱生生命科技有限公司 | Feature expression method and evaluation method for human intestinal health state |
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