CN108126111A

CN108126111A - A kind of Chinese medicine preparation for treating trigeminal neuralgia

Info

Publication number: CN108126111A
Application number: CN201810197948.9A
Authority: CN
Inventors: 杨磊
Original assignee: Individual
Current assignee: Individual
Priority date: 2018-03-12
Filing date: 2018-03-12
Publication date: 2018-06-08

Abstract

The present invention provides a kind of Chinese medicine preparation for treating trigeminal neuralgia, including earthworm, decumbent corydalis tuber, madder, rabbit hair wormwood artemisia, maidenhair, the bletilla striata, convexutricle sedge herb, bog starwort herb, digua fig stem and leaf, Cortex Eucommiae, kuh-seng, cassia twig, Flos Hibisci Rosae-Sinensis, root of Twelve stamen Melastoma, swertia mileensis, franzenbach rhubarb root and rhizome, big Ye Nansu, myrrh, radix scrophulariae, the flower bud of lily magnolia and Radix Glycyrrhizae.By Chinese medicine, on the one hand dredging is through gas, and gas is to then reaching the effect of analgesic, on the other hand by the efficacy of a drug diffusion reach relieve pain, lenitive effect, it is more easy to obtain satisfied clinical therapeutic efficacy, and few relative to traditional remedies medical expense on the whole, have no toxic side effect.

Description

A kind of Chinese medicine preparation for treating trigeminal neuralgia

Technical field

The present invention relates to technical field of Chinese medicine more particularly to a kind of Chinese medicine preparations for treating trigeminal neuralgia.

Background technology

Trigeminal neuralgia is clinically relatively conventional, means ictal, the transience severe pain in trigeminal neuralgia distributed area.Every time The several seconds break out to several minutes, the panic attacks phase, up to tens of times, the sample that such as shocks by electricity bitterly burns sample, cut sample, needle thorn to severe one within one day Sample.This disease be apt to occur in, the elderly, 70%~80% patient fell ill at 40 years old or more.Therapy about trigeminal neuralgia There are many planting, from simple oral drug therapy, physical therapy, to each drug injection closed treating and operation cut-out, avulsion Art, radiofrequency thermoagulation, microvascular decompression etc..Treatment trigeminal neuralgia clinic common method mainly have operation, gamma knife, Radio frequency art, closing, laser, oral western medicine etc..These methods mostly by inhibiting nerve, blocking nerves, destroying nerve, cause three Fork nerve loses normal physiological function, has the function that temporarily to relieve pain.Not only treatment time is long, and medical expense is also relatively It is high；Some results even in damage cranial nerve or brain tissue, also occurs the serious sequelae such as blindness, cerebral hemorrhage, paresis. Western medicine side effect is more apparent, and it is bad to occur dizzy weak, nausea and vomiting, Neuroleptic Leukocytopenia, fash etc. after some patient's uses Reaction.

This disease belongs to the scopes such as the traditional Chinese medical science " wind disease ", " prosopodynia ", mostly excessive due to thinking labor, consumes impairment of yin blood, hyperactivity of yang due to yin deficiency；Or the deficiency of blood Blood stasis, it is impossible to upper honor head channels and collaterals；Or exopathogen wind, phlegm, dampness numbness are with the passing of time, it is strongly fragrant and change fire, it is upper criminal in head.The traditional Chinese medical science falls ill to it Reason, be construed to " this Foot yangming Channel network is passed to channels and collaterals by wind toxin, blood stagnation and it is not all right, therefore have this disease ... ".More Yin Silao mistakes Degree, old age it is hot-tempered with it is melancholy, consumption impairment of yin blood and cause hyperactivity of yang due to yin deficiency.The deficiency of blood or blood stasis cannot go up flourish head channels and collaterals, additional ailment said due to cold or exposure, Phlegm wet resistance numbness is with the passing of time, strongly fragrant and change and violate and cause in Head And Face on fire.This disease eventually be since wind toxin causes, it is determined that using wind-dispelling removing toxic substances as Base therapy principle.Traditional Chinese medicine thinks that malicious heresy is exactly to refer to the substance or script being not present in body in normal living process The substance for adapting to body vital movement has been more than the demand of viable organism and body is formed and is endangered.Therefore in the treatment with heat-clearing Removing toxic substances, temperature three-way meridian, sensible analgesic, nourishing yin and lessening fire, soft liver kidney tonifying are principle, and the present invention is exactly the base in this Chinese traditional treatment theory The Chinese medicine preparation for the treatment of trigeminal neuralgia proposed on plinth, is matched by controlling outside with interior control, and by liniment, gets through patient Blood vessels and channels and collaterals are occluded, promotes qi and blood unobstructed, alleviates the state of an illness, play the role of " controlling outside "；It " is inside controlled " by oral drugs, the two knot It closes, Chinese medicine, on the one hand through gas, on the other hand gas reaches alleviation to the effect of analgesic is then reached by efficacy of a drug diffusion for dredging Pain, lenitive effect are more easy to obtain satisfied clinical therapeutic efficacy on the whole.

Invention content

The technical problems to be solved by the invention are to provide a kind of Chinese medicine preparation for treating trigeminal neuralgia, pass through inside and outside conjunction It controls, on the one hand through gas, on the other hand gas is reached by efficacy of a drug diffusion to the effect of analgesic is then reached and relieves pain, mitigates for dredging The effect of pain is more easy to obtain satisfied clinical therapeutic efficacy, and, nontoxic pair few relative to traditional remedies medical expense on the whole Effect.

In order to solve the above technical problems, the present invention provides a kind of Chinese medicine preparation for treating trigeminal neuralgia, bulk pharmaceutical chemicals Including earthworm, decumbent corydalis tuber, madder, rabbit hair wormwood artemisia, maidenhair, the bletilla striata, convexutricle sedge herb, bog starwort herb, digua fig stem and leaf, Cortex Eucommiae, kuh-seng, cassia twig, Flos Hibisci Rosae-Sinensis, root of Twelve stamen Melastoma, swertia mileensis, franzenbach rhubarb root and rhizome, big Ye Nansu, myrrh, radix scrophulariae, the flower bud of lily magnolia and Radix Glycyrrhizae.

Wherein, the weight of each bulk pharmaceutical chemicals is respectively earthworm 45g~55g, decumbent corydalis tuber 25g~35g, madder in the drug 15g~25g, rabbit hair wormwood artemisia 20g~30g, maidenhair 20g~30g, bletilla striata 30g~40g, convexutricle sedge herb 10g~20g, bog starwort herb 15g ~25g, digua fig stem and leaf 15g~25g, Cortex Eucommiae 20g~30g, kuh-seng 15g~25g, cassia twig 20g~30g, Flos Hibisci Rosae-Sinensis 25g~35g, M.-dodecandrum roots 5g~15g, swertia mileensis 20g~30g, franzenbach rhubarb root and rhizome 10g~20g, great Ye south Soviet Union 15g~25g, myrrh 15g~25g, radix scrophulariae 30g~40g, flower bud of lily magnolia 25g~35g and Radix Glycyrrhizae 10g~20g.

Beneficial effects of the present invention:

The Chinese medicine preparation for the treatment of trigeminal neuralgia provided by the invention, by Chinese medicine, on the one hand dredging is through gas, and gas is to then reaching To analgesic the effect of, on the other hand by the efficacy of a drug diffusion reach relieve pain, lenitive effect, be more easy to be expired on the whole The clinical therapeutic efficacy of meaning, and it is few relative to traditional remedies medical expense, it has no toxic side effect.

Specific embodiment

The present invention will be described in detail below with reference to the drawings of preferred embodiments, whereby to the present invention how applied technology method To solve technical problem, and the realization process for reaching technique effect can fully understand and implement according to this.

Embodiment 1

Take earthworm 50g, decumbent corydalis tuber 30g, maidenhair 25g, bletilla striata 35g, convexutricle sedge herb 15g, cassia twig 25g, Flos Hibisci Rosae-Sinensis 30g, root of Twelve stamen Melastoma 10g, swertia mileensis 25g, franzenbach rhubarb root and rhizome 15g, great Ye south Soviet Union 20g, radix scrophulariae 35g, flower bud of lily magnolia 30g and Radix Glycyrrhizae 15g, are respectively crushed into powder, It is put into stirrer for mixing to stir evenly, add water to cook twice, for the first time plus water 3.6kg, decoction 2h second plus water 3kg, are decocted Boil 1.5h, collecting decoction, 0.08MPa, relative density is 1.15 when being concentrated under reduced pressure into 70 DEG C at 70 DEG C, adds 95% (v/v) ethyl alcohol Make alcohol content up to 75% (v/v), stirring is stood overnight, and is filtered, and filtrate is concentrated under reduced pressure under the conditions of 0.08MPa, 65 DEG C into 65 DEG C when relative density be 1.15g/mL, obtain the first extracting solution, by madder 20g, rabbit hair wormwood artemisia 25g, bog starwort herb 20g, digua fig stem and leaf 20g, Cortex Eucommiae 25g, kuh-seng 20g, myrrh 20g are respectively crushed into powder, are put into stirrer for mixing by weight and stir evenly, and add in The determining alcohol of 900g is 65% ethyl alcohol, is heated to reflux 3 hours, is filtered；The ethyl alcohol that the determining alcohol that filter residue adds in 600g is 65%, It is heated to reflux 2 hours, filters；It filtrate will mix twice, vacuum distillation removes ethyl alcohol, obtains the second extracting solution, by the second extraction Liquid is added in the first extracting solution, is stirred evenly, and it is 1.30 to be concentrated into 70 DEG C of relative densities, obtains Chinese medical concrete, takes Chinese medical concrete 150g adds in honey 100g, sucrose 90g, sodium benzoate 3.0g and appropriate amount of water, mixing, add sodium hydroxide test solution tune pH value to 5~ 6, add water to 1000ml, filter, embedding, sterilize to get.

Embodiment 2

Take earthworm 48g, decumbent corydalis tuber 28g, maidenhair 23g, bletilla striata 33g, convexutricle sedge herb 13g, cassia twig 23g, Flos Hibisci Rosae-Sinensis 28g, root of Twelve stamen Melastoma 8g, swertia mileensis 23g, franzenbach rhubarb root and rhizome 13g, great Ye south Soviet Union 18g, radix scrophulariae 33g, flower bud of lily magnolia 28g and Radix Glycyrrhizae 13g, are respectively crushed into powder, put Enter stirrer for mixing to stir evenly, add water to cook twice, for the first time plus water 3.6kg, decoction 2h second plus water 3kg, are decocted 1.5h, collecting decoction, 0.08MPa, relative density is 1.15 when being concentrated under reduced pressure into 70 DEG C at 70 DEG C, and 95% (v/v) ethyl alcohol is added to make Alcohol content is stood overnight up to 75% (v/v), stirring, is filtered, and filtrate is concentrated under reduced pressure under the conditions of 0.08MPa, 65 DEG C into 65 DEG C When relative density be 1.15g/mL, obtain the first extracting solution, by madder 18g, rabbit hair wormwood artemisia 23g, bog starwort herb 18g, digua fig stem and leaf 18g, Cortex Eucommiae 23g, kuh-seng 18g, myrrh 18g are respectively crushed into powder, are put into stirrer for mixing by weight and stir evenly, and add in 900g Determining alcohol be 65% ethyl alcohol, be heated to reflux 3 hours, filter；The ethyl alcohol that the determining alcohol that filter residue adds in 600g is 65%, heating Reflux 2 hours, filtering；It filtrate will mix twice, vacuum distillation removes ethyl alcohol, obtains the second extracting solution, the second extracting solution is added Enter in the first extracting solution, stir evenly, it is 1.30 to be concentrated into 70 DEG C of relative densities, obtains Chinese medical concrete, takes Chinese medical concrete 150g, Honey 100g, sucrose 90g, sodium benzoate 3.0g and appropriate amount of water, mixing are added in, sodium hydroxide test solution tune pH value is added to add to 5~6 Water is to 1000ml, filtration, embedding, sterilize to get.

Embodiment 3

Take earthworm 52g, decumbent corydalis tuber 32g, maidenhair 27g, bletilla striata 37g, convexutricle sedge herb 17g, cassia twig 27g, Flos Hibisci Rosae-Sinensis 32g, root of Twelve stamen Melastoma 12g, swertia mileensis 27g, franzenbach rhubarb root and rhizome 17g, great Ye south Soviet Union 22g, radix scrophulariae 37g, flower bud of lily magnolia 32g and Radix Glycyrrhizae 17g, are respectively crushed into powder, It is put into stirrer for mixing to stir evenly, add water to cook twice, for the first time plus water 3.6kg, decoction 2h second plus water 3kg, are decocted Boil 1.5h, collecting decoction, 0.08MPa, relative density is 1.15 when being concentrated under reduced pressure into 70 DEG C at 70 DEG C, adds 95% (v/v) ethyl alcohol Make alcohol content up to 75% (v/v), stirring is stood overnight, and is filtered, and filtrate is concentrated under reduced pressure under the conditions of 0.08MPa, 65 DEG C into 65 DEG C when relative density be 1.15g/mL, obtain the first extracting solution, by madder 22g, rabbit hair wormwood artemisia 27g, bog starwort herb 22g, digua fig stem and leaf 22g, Cortex Eucommiae 27g, kuh-seng 22g, myrrh 22g are respectively crushed into powder, are put into stirrer for mixing by weight and stir evenly, and add in The determining alcohol of 900g is 65% ethyl alcohol, is heated to reflux 3 hours, is filtered；The ethyl alcohol that the determining alcohol that filter residue adds in 600g is 65%, It is heated to reflux 2 hours, filters；It filtrate will mix twice, vacuum distillation removes ethyl alcohol, obtains the second extracting solution, by the second extraction Liquid is added in the first extracting solution, is stirred evenly, and it is 1.30 to be concentrated into 70 DEG C of relative densities, obtains Chinese medical concrete, takes Chinese medical concrete 150g adds in honey 100g, sucrose 90g, sodium benzoate 3.0g and appropriate amount of water, mixing, add sodium hydroxide test solution tune pH value to 5~ 6, add water to 1000ml, filter, embedding, sterilize to get.

The above described is only a preferred embodiment of the present invention, being not that the invention has other forms of limitations, appoint What those skilled in the art changed or be modified as possibly also with the technology contents of the disclosure above equivalent variations etc. Imitate embodiment.But it is every without departing from technical solution of the present invention content, technical spirit according to the present invention is to above example institute Any simple modification, equivalent variations and the remodeling made still fall within the protection domain of technical solution of the present invention.

Claims

1. a kind of Chinese medicine preparation for treating trigeminal neuralgia, it is characterised in that：Bulk pharmaceutical chemicals are by earthworm, decumbent corydalis tuber, madder, the rabbit hair Wormwood artemisia, maidenhair, the bletilla striata, convexutricle sedge herb, bog starwort herb, digua fig stem and leaf, Cortex Eucommiae, kuh-seng, cassia twig, Flos Hibisci Rosae-Sinensis, root of Twelve stamen Melastoma, swertia mileensis, mountain are big Yellow, big Ye Nansu, myrrh, radix scrophulariae, the flower bud of lily magnolia and Radix Glycyrrhizae are formed；

The weight of each bulk pharmaceutical chemicals be respectively earthworm 45g~55g, decumbent corydalis tuber 25g~35g, madder 15g~25g, rabbit hair wormwood artemisia 20g~ 30g, maidenhair 20g~30g, bletilla striata 30g~40g, convexutricle sedge herb 10g~20g, bog starwort herb 15g~25g, digua fig stem and leaf 15g~25g, Cortex Eucommiae 20g~30g, kuh-seng 15g~25g, cassia twig 20g~30g, Flos Hibisci Rosae-Sinensis 25g~35g, root of Twelve stamen Melastoma 5g~15g, swertia mileensis 20g ~30g, franzenbach rhubarb root and rhizome 10g~20g, great Ye south Soviet Union 15g~25g, myrrh 15g~25g, radix scrophulariae 30g~40g, flower bud of lily magnolia 25g~35g With Radix Glycyrrhizae 10g~20g.