CN108125866A - 一种活力祛斑精华液及其制备方法 - Google Patents

一种活力祛斑精华液及其制备方法 Download PDF

Info

Publication number
CN108125866A
CN108125866A CN201810062118.5A CN201810062118A CN108125866A CN 108125866 A CN108125866 A CN 108125866A CN 201810062118 A CN201810062118 A CN 201810062118A CN 108125866 A CN108125866 A CN 108125866A
Authority
CN
China
Prior art keywords
parts
nti
skin
freckle
vigor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
CN201810062118.5A
Other languages
English (en)
Inventor
王丹
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to CN201810062118.5A priority Critical patent/CN108125866A/zh
Publication of CN108125866A publication Critical patent/CN108125866A/zh
Withdrawn legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/31Hydrocarbons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/35Ketones, e.g. benzophenone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37Esters of carboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/81Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
    • A61K8/817Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen; Compositions or derivatives of such polymers, e.g. vinylimidazol, vinylcaprolactame, allylamines (Polyquaternium 6)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/89Polysiloxanes
    • A61K8/891Polysiloxanes saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone
    • A61K8/893Polysiloxanes saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone modified by an alkoxy or aryloxy group, e.g. behenoxy dimethicone or stearoxy dimethicone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/925Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of animal origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/02Preparations for care of the skin for chemically bleaching or whitening the skin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Emergency Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Zoology (AREA)
  • Cosmetics (AREA)

Abstract

本发明活力祛斑精华液,由以下重量份数的原料制成:聚乙烯吡咯烷酮3~4份、棕榈酸异丙酯5~6份、角鲨烷8~10份、香兰素1.3~1.5份、马油10~12份、聚甲基苯基硅氧烷1~1.2份、杏仁油6~8份、素馨花提取物2~2.5份、鸡蛋果提取物3~4份、砂生槐提取物2.5~3份、山梨醇酐油酸酯2~3份、去离子水50~58份。本发明活力祛斑精华液含有多种营养护肤元素,尤其是加入了素馨花提取物、鸡蛋果提取物、砂生槐提取物;各个营养元素有效配合,协同效应十分突出,通过特殊的工艺制成,形成突出的祛斑、以及增强肌肤活力的效果,相对于一般的化妆品,本发明在祛斑、以及增加肌肤弹性提高肌肤活力方面的功效尤其突出。

Description

一种活力祛斑精华液及其制备方法
技术领域
本发明属于化妆品制备技术领域,具体涉及一种活力祛斑精华液及其制备方法。
背景技术
雀斑是最常见脸部斑点,好发于面部,常呈褐色素点状色素沉着,分布于脸颊、鼻子,严重者会分布全脸。治疗雀斑的方法很多,但效果因人而异,并且很容易复发。果酸祛斑,用高浓度果酸剥脱表皮,较以往的化学剥脱安全可靠,达到“换肤”目的。酵素祛斑,酵素是治疗雀斑、黄褐斑、黑斑的常见方法,作用机理是中和体内自由基源,解除蛋白质变性,从而达到祛斑的目的。在正常情况下,所有肌肤都富有一定的弹性,显得光滑、柔嫩而有张力。但是经过了风吹日晒、季节的变换和现代压力等各种因素,皮肤弹性往往已经不如当初。当皮肤没有弹性,会让女人更加显老,也是女人最丑陋的时候。玻尿酸是常用的曾经肌肤活性的物质,口服玻尿酸吸收水分后,使得弹力纤维及胶原蛋白处在充满湿润的环境中,为外来补充的胶原蛋白合成自身的胶原提供了适宜的环境,提高了胶原蛋白的利用率,皮肤因此具有了弹性。玻尿酸的作用也就体现了出来。常用的祛斑和增强皮肤活力的营养成分有牛油果:从多英霓细岗岩上的坚果里提取,非洲妇女热衷在烹饪及皮肤保养中添加这一物质已有几百年历史。它含 有纯天然润肤成份,保护皮肤免受阳光紫外线伤害,迅速提升、收紧皮肤。 月见草油:作为在纯天然食品和整个医药史上具有重要意义的成份,它在皮肤护理方面功效非凡,尤其能帮助缓解 皮肤干燥缺水的状况。
发明内容
本发明的目的是提供一种能够激发皮肤活力提高皮肤弹性和具有祛斑效果的活力祛斑精华液及其制备方法。
本发明活力祛斑精华液,由以下重量份数的原料制成:聚乙烯吡咯烷酮3~4份、棕榈酸异丙酯5~6份、角鲨烷8~10份、香兰素1.3~1.5份、马油10~12份、聚甲基苯基硅氧烷1~1.2份、杏仁油6~8份、素馨花提取物2~2.5份、鸡蛋果提取物3~4份、砂生槐提取物2.5~3份、山梨醇酐油酸酯2~3份、去离子水50~58份。
作为优化,该活力祛斑精华液,是由以下重量份数的原料制成:聚乙烯吡咯烷酮3.3份、棕榈酸异丙酯5.2份、角鲨烷9份、香兰素1.4份、马油11份、聚甲基苯基硅氧烷1份、杏仁油8份、素馨花提取物2.2份、鸡蛋果提取物3.5份、砂生槐提取物2.8份、山梨醇酐油酸酯2.3份、去离子水55份。
制备本发明活力祛斑精华液的方法,包括以下步骤:
a、将所述重量份数的棕榈酸异丙酯、角鲨烷、马油、聚甲基苯基硅氧烷、杏仁油,在72℃~78℃条件下,加入搅拌机中以1000转/分钟的转速搅拌12分钟;
b、将所述重量份数的聚乙烯吡咯烷酮、香兰素、去离子水,在45℃~ 50℃条件下,加入搅拌机中以800转/分钟的转速搅拌8分钟;
c、将所述重量份数的素馨花提取物、鸡蛋果提取物、砂生槐提取物、山梨醇酐油酸酯(Span-80)加入到步骤b中的混合物中,在55℃~60℃条件下,以800转/分钟的转速搅拌10分钟;然后加入步骤a中的混合物,在60℃~65℃条件下,以1000转/分钟的转速搅拌25分钟即成。
本发明活力祛斑精华液组分中,鸡蛋果中富含的VC、胡萝卜素、SOD酶能够清除体内自由基,起养颜抗衰老作用。鸡蛋果提取物为鸡蛋果的乙醇提取物,可以通过乙醇回流提取法获得。素馨花的气味非常芳香,是常用的花类药,有舒肝解郁、行气止痛、生津益气、养肝明目、排毒养颜及健胃消积的作用。素馨花提取物为素馨花的乙醇提取物,可以通过乙醇回流提取法获得。砂生槐具有消炎解毒功效;砂生槐提取物,由砂生槐的果实通过乙醇回流提取法获得。角鲨烷为最接近人体皮脂的一种脂类,亲和力强,能够与人类自身的皮脂膜融为一体,在皮肤表面形成一层天然的屏障。马油是一种动物油,含有丰富的自然营养素、高度不饱和脂肪酸,及维他命E,使得马油可以渗入极微小的间隙中。杏仁油富含蛋白质、不饱和脂肪酸、维生素、无机盐、膳食纤维及人体所需的微量元素,具有润肺、健胃、补充体力的作用,其苦杏仁甙更是天然的抗癌活性物质。
本发明活力祛斑精华液含有多种营养护肤元素,尤其是加入了素馨花提取物、鸡蛋果提取物、砂生槐提取物;各个营养元素有效配合,协同效应十分突出,通过特殊的工艺制成,形成突出的祛斑、以及增强肌肤活力的效果,相对于一般的化妆品,本发明在祛斑、以及增加肌肤弹性提高肌肤活力方面的功效尤其突出。
相关测试如下,测试分组:共纳入女性试用者243 人,年龄最大48 岁,最小26 岁,平均年龄36岁左右。分为三组每组81人,分别为A组,空白组;B组,日本北海道LOSHI护肤滋润面霜乳霜;C组,本发明实施例1中的活力祛斑精华液。每人每天早、晚使用一次。30日之后观察结果。
祛斑效果测试:评价标准:皮损颜色评分:正常肤色0分,淡褐色1分,褐色2分,深褐色3分。皮损面积评分:无皮损0分:皮损面积小于2cm为1分,皮损面积2~4cm为2分;皮损面积大于4cm为3分。下降指数计算:总积分=颜色评分+面积评分。下降指数I=(治疗前积分一治疗后积分)/ 治疗前总积。
效果标准:(1)痊愈:色斑面积90%以上消退,基本颜色消失:下降指数I大于等于0.8。 (2)显效:色斑面积60%以上消退,明显颜色变淡;下降指数I大于0.5。 (3)好转:色斑面积30%以上消退,颜色略有变淡;下降指数I大于0.3。(4)无效:斑消退面积小于30%,颜色消退不明显;治疗后下降指数小于0。一个月后测试结果见表1。
皮肤弹性测试,使用MPA580弹性测试仪,弹性的测定指数为R2,R2=(e(a) - e(a+b) / e(a):即无负压时皮肤的回弹量和有负压时的最大拉伸量之比,比值越接近于1,说明皮肤弹性越好。一个月后测试结果见表2。
通过以上测试可见,C组采用本发明活力祛斑精华液,使用后C组测试者的祛斑效果明显大与A组和B组中的祛斑效果;通过MPA580弹性测试仪测试可见C组使用者的使用后的皮肤弹性明显大于其他组。因此,本发明活力祛斑精华液在祛斑、以及增强肌肤弹性提高肌肤活力方面的功效尤其突出。
具体实施方式
下面给出的实施例拟对本发明作进一步说明,但不能理解为是对本发明保护范围的限制,本领域技术人员根据本发明内容对本发明的一些非本质的改进和调整,仍属于本发明的保护范围。
实施例1:a、取棕榈酸异丙酯5.2千克、角鲨烷9千克、马油11千克、聚甲基苯基硅氧烷1千克、杏仁油8千克,在72℃~78℃条件下,加入搅拌机中以1000转/分钟的转速搅拌12分钟;
b、取聚乙烯吡咯烷酮3.3千克、香兰素1.4千克、去离子水55千克,在45℃~ 50℃条件下,加入搅拌机中以800转/分钟的转速搅拌8分钟;
c、取素馨花提取物2.2千克、鸡蛋果提取物3.5千克、砂生槐提取物2.8千克、山梨醇酐油酸酯2.3千克加入到步骤b中的混合物中,在55℃~60℃条件下,以800转/分钟的转速搅拌10分钟;然后加入步骤a中的混合物,在60℃~65℃条件下,以1000转/分钟的转速搅拌25分钟即成。
实施例2:a、取棕榈酸异丙酯5千克、角鲨烷8千克、马油10千克、聚甲基苯基硅氧烷1千克、杏仁油6千克,在72℃~78℃条件下,加入搅拌机中以1000转/分钟的转速搅拌12分钟;
b、取聚乙烯吡咯烷酮3千克、香兰素1.3千克、去离子水50千克,在45℃~ 50℃条件下,加入搅拌机中以800转/分钟的转速搅拌8分钟;
c、取素馨花提取物2千克、鸡蛋果提取物3千克、砂生槐提取物2.5千克、山梨醇酐油酸酯2千克(Span-80)加入到步骤b中的混合物中,在55℃~60℃条件下,以800转/分钟的转速搅拌10分钟;然后加入步骤a中的混合物,在60℃~65℃条件下,以1000转/分钟的转速搅拌25分钟即成。
实施例3:a、取棕榈酸异丙酯6千克、角鲨烷10千克、马油12千克、聚甲基苯基硅氧烷1.2千克、杏仁油8千克,在72℃~78℃条件下,加入搅拌机中以1000转/分钟的转速搅拌12分钟;
b、取聚乙烯吡咯烷酮4千克、香兰素1.5千克、去离子水58千克,在45℃~ 50℃条件下,加入搅拌机中以800转/分钟的转速搅拌8分钟;
c、取素馨花提取物2.5千克、鸡蛋果提取物4千克、砂生槐提取物3千克、山梨醇酐油酸酯3千克加入到步骤b中的混合物中,在55℃~60℃条件下,以800转/分钟的转速搅拌10分钟;然后加入步骤a中的混合物,在60℃~65℃条件下,以1000转/分钟的转速搅拌25分钟即成。

Claims (1)

1.一种活力祛斑精华液,其特征在于是由以下步骤制成:
a、取棕榈酸异丙酯5份、角鲨烷8份、马油10份、聚甲基苯基硅氧烷1份、杏仁油6份,在72℃~78℃条件下,加入搅拌机中以1000转/分钟的转速搅拌12分钟;
b、取聚乙烯吡咯烷酮3份、香兰素1.3份、去离子水50份,在45℃~ 50℃条件下,加入搅拌机中以800转/分钟的转速搅拌8分钟;
c、取素馨花提取物2份、鸡蛋果提取物3份、砂生槐提取物2.5份、山梨醇酐油酸酯2份,加入到步骤b中的混合物中,在55℃~60℃条件下,以800转/分钟的转速搅拌10分钟;然后加入步骤a中的混合物,在60℃~65℃条件下,以1000转/分钟的转速搅拌25分钟即成。
CN201810062118.5A 2015-10-15 2015-10-15 一种活力祛斑精华液及其制备方法 Withdrawn CN108125866A (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201810062118.5A CN108125866A (zh) 2015-10-15 2015-10-15 一种活力祛斑精华液及其制备方法

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN201810062118.5A CN108125866A (zh) 2015-10-15 2015-10-15 一种活力祛斑精华液及其制备方法
CN201510664438.4A CN105168067B (zh) 2015-10-15 2015-10-15 一种活力祛斑精华液及其制备方法

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CN201510664438.4A Division CN105168067B (zh) 2015-10-15 2015-10-15 一种活力祛斑精华液及其制备方法

Publications (1)

Publication Number Publication Date
CN108125866A true CN108125866A (zh) 2018-06-08

Family

ID=54890851

Family Applications (2)

Application Number Title Priority Date Filing Date
CN201510664438.4A Active CN105168067B (zh) 2015-10-15 2015-10-15 一种活力祛斑精华液及其制备方法
CN201810062118.5A Withdrawn CN108125866A (zh) 2015-10-15 2015-10-15 一种活力祛斑精华液及其制备方法

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CN201510664438.4A Active CN105168067B (zh) 2015-10-15 2015-10-15 一种活力祛斑精华液及其制备方法

Country Status (1)

Country Link
CN (2) CN105168067B (zh)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111920853B (zh) * 2020-08-14 2022-04-08 五邑大学 素馨花及其提取物在制备治疗高脂血症、代谢综合征或非酒精性脂肪肝病药物中的应用
CN116019759A (zh) * 2023-03-03 2023-04-28 杨森 儿童修复保湿洗发沐浴二合一组合物

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20100042090A (ko) * 2008-10-15 2010-04-23 인하대학교 산학협력단 자스민 추출물을 유효성분으로 함유하는 미백용 조성물
CN104257575A (zh) * 2014-09-04 2015-01-07 杨珍 祛皱抗氧化维他命c养肤粉

Also Published As

Publication number Publication date
CN105168067A (zh) 2015-12-23
CN105168067B (zh) 2018-03-02

Similar Documents

Publication Publication Date Title
KR101373636B1 (ko) 천연물 복합 발효 추출물을 유효성분으로 하는 피부 및 두피 상태 개선용 조성물
CN103340817B (zh) 一种葛根美白面膜
CN105687055A (zh) 一种眼部修护精华液及其制备方法
CN105168054A (zh) 一种补水增白祛皱面膜及其制备方法
CN106265478A (zh) 一种具有丰胸功效的护肤组合物及其应用
CN108653013A (zh) 一种植物保湿水润晒后修复霜及其制备方法
KR101839013B1 (ko) 모자반 추출물, 청각 추출물 및 참미역 추출물을 함유하는 화장료 조성물
CN106420482A (zh) 一种肌能赋活水光精华液
CN107693456A (zh) 一种天然茶油面霜及其制备方法
CN106236689A (zh) 一种美白保湿霜及其制备方法
KR101312965B1 (ko) 양파, 컴프리, 한련초 및 카카오 추출물을 함유하는 탄력 증진 및 주름 개선 화장용 조성물
CN108653006A (zh) 一种植物保湿全效眼霜及其制备方法
CN105616312A (zh) 一种祛斑化妆品及其制备方法
CN106309340A (zh) 一种柚子汁抗皱去纹护肤配方
CN113952258A (zh) 孕期专用的植萃保湿水润精油及其制备工艺
CN108785163A (zh) 丰胸乳膏及其制备方法和使用方法
CN108495616A (zh) 有效成分包含海洋燕窝复合发酵提取物的用于改善皮肤皱纹的组合物以及利用该组合物用于改善皮肤皱纹的贴片和面膜
CN105168109B (zh) 一种祛斑保湿护肤品及其制备方法
CN105168067B (zh) 一种活力祛斑精华液及其制备方法
KR101418825B1 (ko) 바다제비집 및 병풀의 복합발효추출물을 유효성분으로 포함하는 피부 자극 완화용 조성물
KR101835799B1 (ko) 프로폴리스를 유효성분으로 함유하는 화장품 조성물 및 상기 조성물을 포함하는 화장품
CN104224676A (zh) 螺旋藻抗皱防衰老面膜
CN106333897A (zh) 一种含辣木活性成分的修复精华液及其制备方法
CN107441340B (zh) 一种消肿止痛止痒滋养皮肤的手足皴裂膏及其制备方法
CN109330925A (zh) 一种纯天然海藻泥面膜及其制备方法

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
WW01 Invention patent application withdrawn after publication
WW01 Invention patent application withdrawn after publication

Application publication date: 20180608