CN108120683B - Adjustable light source device for biochemical analyzer - Google Patents
Adjustable light source device for biochemical analyzer Download PDFInfo
- Publication number
- CN108120683B CN108120683B CN201711430777.1A CN201711430777A CN108120683B CN 108120683 B CN108120683 B CN 108120683B CN 201711430777 A CN201711430777 A CN 201711430777A CN 108120683 B CN108120683 B CN 108120683B
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- light path
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- 230000003287 optical effect Effects 0.000 claims description 13
- 230000000149 penetrating effect Effects 0.000 claims description 6
- 239000013307 optical fiber Substances 0.000 claims description 4
- 238000001514 detection method Methods 0.000 abstract description 19
- 238000004519 manufacturing process Methods 0.000 abstract description 2
- 238000004458 analytical method Methods 0.000 description 7
- 230000007246 mechanism Effects 0.000 description 5
- 238000004879 turbidimetry Methods 0.000 description 3
- 230000009471 action Effects 0.000 description 2
- 230000005540 biological transmission Effects 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 239000000758 substrate Substances 0.000 description 2
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 229910052736 halogen Inorganic materials 0.000 description 1
- 150000002367 halogens Chemical class 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 238000004848 nephelometry Methods 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 229910052710 silicon Inorganic materials 0.000 description 1
- 239000010703 silicon Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
Abstract
The invention discloses an adjustable light source device for a biochemical analyzer, which comprises a first base and a second base, wherein at least one first light path channel is horizontally arranged between the front wall and the rear wall of the first base, a first lens is arranged at the front end of the first light path channel, and a first light source is arranged at the rear end of the first light path channel; the second base is arranged at one end of the first base in parallel along the transverse direction, can rotate around a rotating shaft relative to the first base and extends along the transverse direction of the axis of the rotating shaft; at least one inclined second light path channel is arranged between the front wall and the rear wall of the second base, a second lens is arranged at the front end of the second light path channel, and a second light source is arranged at the rear end of the second light path channel. According to the technical scheme, when in actual detection, the light source on the first base or the second base can be adopted to detect the sample in the color comparison cup according to actual needs, and the color comparison cup is simple in structure, low in manufacturing cost, convenient to adjust and wide in application range.
Description
Technical Field
The invention relates to the technical field of medical detection instruments, in particular to an adjustable light source device for a biochemical analyzer.
Background
The structure of the biochemical detection and analysis device generally adopts a turntable structure, a plurality of cuvette slots are distributed on the circumference of the turntable, the detection device is arranged at a position matched with one of the cuvette slots, and the cuvette in the plurality of slots is sequentially detected by rotating the turntable, and the biochemical detection and analysis device has the advantages of complex structure, high design precision requirement and high cost, and is not beneficial to popularization into a social rehabilitation center or a small medical institution;
the biochemical detection and analysis device usually adopts a scattering immune turbidimetry principle or a projection immune turbidimetry principle to detect and analyze a sample, but the light source of the existing biochemical detection and analysis device is fixedly arranged but cannot be adjusted, namely, the light path channel through which the light emitted by the light source passes is fixed, so that the two detection and analysis modes cannot be simultaneously considered, and the use has limitations.
Disclosure of Invention
The invention aims to at least solve the defects in the prior art to a certain extent and provides a tunable light source device for a biochemical analyzer.
To achieve the above object, the present invention provides a tunable light source apparatus for a biochemical analyzer, comprising:
the device comprises a first base, wherein at least one first light path channel is horizontally arranged between the front wall and the rear wall of the first base, a first lens is arranged at the front end of the first light path channel, and a first light source is arranged at the rear end of the first light path channel;
the second base is arranged at one end of the first base in parallel along the transverse direction, can rotate around a rotating shaft relative to the first base and extends along the transverse direction along the axial direction of the rotating shaft; at least one second light path channel is arranged between the front wall and the rear wall of the second base, a second lens is arranged at the front end of the second light path channel, and a second light source is arranged at the rear end of the second light path channel; the irradiation angle of the second light path channel is adjusted by the rotation angle of the second base.
Preferably, a limiting member is disposed between the first base and the second base to limit the rotation angle of the second base.
Preferably, the second base is provided with an arc sliding hole in a penetrating way along the transverse direction, and the circle center of the arc sliding hole is positioned on the axis of the rotating shaft;
the limiting piece is a limiting screw, a threaded hole extending transversely is formed in the end face, facing the second base, of the first base, the limiting screw penetrates through the arc-shaped sliding hole to be connected into the threaded hole, and the second base is fixed to the first base.
Preferably, each of the first light source and the second light source is mounted on the rear end of the corresponding first light path channel and the corresponding second light path channel through a light source mounting seat and a connecting pipe, one end of the light source mounting seat is provided with a light source mounting hole, the other end of the light source mounting seat is provided with a communication hole connected with the light source mounting hole, one end of the connecting pipe is fixedly inserted into the communication hole, the other end of the connecting pipe is fixedly inserted into the rear end of the first light path channel or the second light path channel, and the central axis of each connecting pipe is provided with an optical fiber penetrating through two ends of the connecting pipe.
Preferably, the rear end of the first base corresponds to each first light path channel and is provided with a first locking screw hole vertically communicated with the first light path channel, the rear end of the second base corresponds to each second light path channel and is provided with a second locking screw hole vertically communicated with the second light path channel, the light source mounting seat corresponds to each communication hole and is provided with a third locking screw hole vertically communicated with the communication hole, one end of the connecting pipe is fixed with the light source mounting seat through the cooperation of the locking screw and each locking screw hole, and the other end of the connecting pipe is fixed with the first base or the second base.
Preferably, a light source mounting plate is disposed at one end of each light source mounting seat corresponding to the light source mounting hole, so as to fix the first light source or the second light source in the light source mounting hole.
Preferably, the front end of each of the first optical path channel and the second optical path channel is provided with a lens mounting hole, the front ends of the first base and the second base are respectively provided with a lens mounting plate corresponding to each lens mounting hole, the first lens and the second lens are fixed in the lens mounting holes of the corresponding first optical path channel and the second optical path channel, and each lens mounting plate is provided with a through hole opposite to the lens mounting hole.
According to the technical scheme, the first base and the second base are arranged side by side, the first base is provided with the horizontal first light path channel, the second base is provided with the inclined second light path channel, and the second base can rotate around a transversely arranged rotating shaft relative to the second base, so that the inclination angle of the second light path channel can be adjusted; when in actual detection, the light source on the first base or the second base can be adopted to detect the sample in the color comparison cup according to actual needs, and the color comparison cup has the advantages of simple structure, low manufacturing cost, convenient adjustment and wide application range.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings that are required in the embodiments or the description of the prior art will be briefly described, and it is obvious that the drawings in the following description are only some embodiments of the present invention, and other drawings may be obtained according to the structures shown in these drawings without inventive effort for a person skilled in the art.
FIG. 1 is a schematic diagram of a tunable light source apparatus according to the present invention;
FIG. 2 is an exploded view of FIG. 1;
FIG. 3 is a schematic cross-sectional view of a first light path of the present invention;
FIG. 4 is a schematic cross-sectional view of a second light path of the present invention;
FIG. 5 is a schematic diagram of a biochemical analyzer according to an embodiment of the present invention.
Detailed Description
Embodiments of the present invention are described in detail below, examples of which are illustrated in the accompanying drawings, wherein like or similar reference numerals refer to like or similar elements or elements having like or similar functions throughout. The embodiments described below are exemplary and intended to illustrate the present invention and should not be construed as limiting the invention, and all other embodiments, based on the embodiments of the present invention, which may be obtained by persons of ordinary skill in the art without inventive effort, are within the scope of the present invention.
In the description of the present invention, it should be understood that the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", "axial", "circumferential", "radial", etc. indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings are merely for convenience in describing the present invention and simplify the description, and do not indicate or imply that the device or element being referred to must have a specific orientation, be configured and operated in a specific orientation, and therefore should not be construed as limiting the present invention.
Furthermore, the terms "first," "second," and the like, are used for descriptive purposes only and are not to be construed as indicating or implying a relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defining "a first" or "a second" may explicitly or implicitly include one or more such feature. In the description of the present invention, the meaning of "a plurality" is two or more, unless explicitly defined otherwise.
In the present invention, unless explicitly specified and limited otherwise, the terms "mounted," "connected," "secured," and the like are to be construed broadly and may be, for example, fixedly connected, detachably connected, or integrally connected; can be mechanically or electrically connected; can be directly connected or indirectly connected through an intermediate medium, and can be communication between two elements. The specific meaning of the above terms in the present invention can be understood by those of ordinary skill in the art according to the specific circumstances.
In the present invention, unless expressly stated or limited otherwise, a first feature "above" or "below" a second feature may include both the first and second features being in direct contact, as well as the first and second features not being in direct contact but being in contact with each other through additional features therebetween. Moreover, a first feature being "above," "over" and "on" a second feature includes the first feature being directly above and obliquely above the second feature, or simply indicating that the first feature is higher in level than the second feature. The first feature being "under", "below" and "beneath" the second feature includes the first feature being directly under and obliquely below the second feature, or simply means that the first feature is less level than the second feature.
The adjustable light source device for a biochemical analyzer according to an embodiment of the present invention is described in detail below with reference to the accompanying drawings.
As shown in fig. 1 to 4, the adjustable light source device 20 according to the embodiment of the invention includes a first base 21 connected to the first driving mechanism 40 and a second base 22 disposed side by side with the first base 21 along a lateral direction, wherein the second base 22 can be rotationally adjusted around a rotation axis 214 relative to the first base 21, and the axial direction of the rotation axis 214 extends along the lateral direction.
At least one first light path channel 212 is horizontally arranged between the front wall and the rear wall of the first base 21, a first lens 24A is disposed at the front end of the first light path channel 212, and a first light source 25A is disposed at the rear end of the first light path channel. At least one second light path channel 223 is arranged between the front wall and the rear wall of the second base 22, the front end of the second light path channel 223 is provided with a second lens 24B, and the rear end is provided with a second light source 25B; the irradiation angle of the second optical path 223 is adjusted by the rotation angle of the second base 22.
Further, as shown in fig. 1 and 2, a limiting member is disposed between the first base 21 and the second base 22 to limit the rotation angle of the second base 22, and the rotation angle of the second base 22 is limited to limit the angle of the second light path 223, so that the incident light of the second light source 25B is emitted along the second light path 223 in an upward inclination and then irradiates on the cuvette to be detected, and the angle between the second light path 223 and the horizontal plane is adjustable between 10 ° and 37 °.
Specifically, the second base 22 is provided with an arc sliding hole 222 penetrating in the transverse direction, and the center of the arc sliding hole 222 is located on the axis of the rotating shaft 214; the limiting member is a limiting screw 23, a threaded hole 211 extending in a transverse direction is provided on an end surface of the first base 21 facing the second base 22, and the limiting screw 23 passes through the arc sliding hole 222 to be connected to the threaded hole 211, and fixes the second base 22 on the first base 21.
The rotating shaft 214 is arranged on the first base 21, and protrudes and extends from the first base 21 to the second base 22 along the transverse direction, and the distance between the axis of the rotating shaft 214 and the axis of the threaded hole 211 is equal to the radius of the arc-shaped sliding hole 222; the second base 22 is provided with a shaft hole 221 for sleeving the rotating shaft 214 along the transverse direction on the center of the arc sliding hole 222; when the device is installed, the second base 22 is sleeved on the rotating shaft 214 along the transverse direction, and the screw rod of the limit screw 23 passes through the arc-shaped sliding hole 222 to be connected to the threaded hole 211 in a threaded manner, so that the head of the limit screw 23 presses and fixes the second base 22 on the first base 21, and the second base 22 and the first base 21 are fixed; when the angle of the second light path 223 of the second base 22 needs to be adjusted, the limit screw 23 is loosened slightly, the second base 22 is rotated to a desired angle around the axis of the rotation shaft 214, and then the limit screw 23 is tightened to fix the second base 22.
The first light path channels 212 on the first base 21 of the present embodiment are four and parallel to each other, and the corresponding first light sources 25A are also four, and the wavelengths of the light emitted by the first light sources 25A are different; the second light path 223 on the second base 22 has two second light sources 25B, which are parallel to each other, and the wavelengths of the light emitted by the two second light sources 25B are different. That is, the tunable light source device for a biochemical analyzer of the present embodiment can determine whether to use the first light source 25A or the second light source 25B for irradiation according to the principle of scattering immunonephelometry or transmission immunonephelometry, and select the light source with the corresponding wavelength according to the detection requirement; for example, when the detection is performed according to the principle of the nephelometry by scattering, a second light path 223 on the second base 22 is aligned with the cuvette containing the sample, the light emitted by the second light source 25B is injected into the cuvette along the second light path 223 at a preset angle, and the light is deflected by the refraction of the compound particles in the sample, is emitted from the second light through hole and is received by the detection head of the biochemical analyzer for detection and analysis; if the detection is performed according to the principle of transmission turbidimetry, a first light path 212 on the first base 21 is used for aligning the cuvette, and the light emitted by the second light source 25B passes through the cuvette along the horizontal direction and is received by the detection head for detection and analysis.
Each first light source 25A or each second light source 25B is respectively mounted on the corresponding first light path channel 212 or second light path channel 223 through a light source mounting seat 26 and a connecting pipe 27, one end of the light source mounting seat 26 is provided with a light source mounting hole 261, the other end is provided with a communication hole 262 connected with the light source mounting hole 261, one end of the connecting pipe 27 is inserted and fixed in the communication hole 262 and is opposite to the first light source 25A or the second light source 25B positioned in the light source mounting hole 261, the other end of the connecting pipe 27 is inserted and fixed on one end of the first light path channel 212 or the second light path channel 223 far away from the sample frame 10, and the central axis of each connecting pipe 27 is provided with an optical fiber 271 penetrating through two ends of the connecting pipe 27; thus, the light emitted by the first light source 25A or the second light source 25B on the light source mounting seat 26 enters the corresponding light path channel after passing through the optical fiber 271, and irradiates on the cuvette through the focusing action of the lens.
The first base 21 is provided with a first locking screw hole 213 vertically communicated with the first light path channel 212 on the end, which is inserted with the connecting pipe 27, corresponding to each first light path channel 212, the second base 22 is provided with a second locking screw hole 224 vertically communicated with each second light path channel 223 on the end, which is inserted with the connecting pipe 27, corresponding to each second light path channel 223, and the light source mounting seat 26 is provided with a third locking screw hole 263 vertically communicated with the communication hole 262 on the end, which is inserted with the connecting pipe 27; after one end of the connection pipe 27 is inserted into the communication hole 262, the connection pipe 27 is fixed with the light source mounting seat 26 by pressing the connection pipe 27 in the third locking screw hole 263 by adopting a locking screw; after the other end of the connection pipe 27 is inserted into the first optical path channel 212 or the second optical path channel 223, the connection pipe 27 is connected in the corresponding first locking screw hole 213 or second locking screw hole 224 by using a locking screw to press the connection pipe 27, so that the connection pipe 27 is fixed with the first base 21 or the second base 22.
A light source mounting plate 264 is disposed at one end of each light source mounting seat 26 corresponding to the light source mounting hole 261 for fixing the first light source 25A or the second light source 25B in the light source mounting hole 261 of the corresponding light source mounting seat 26.
A lens mounting hole is formed at one end of each of the first optical path channel 212 or the second optical path channel 223 near the sample frame 10, a lens mounting plate 28 is disposed at one end of the first base 21 or the second base 22 corresponding to each lens mounting hole, for fixing the first lens 24A or the second lens 24B in each lens mounting hole of the corresponding first optical path channel 212 or the second optical path channel 223, and a through hole 281 opposite to the lens mounting hole is formed in each lens mounting plate 28.
As shown in fig. 5, the present invention provides a biochemical analyzer using the above-mentioned adjustable light source device 20, which includes a substrate 100, and a sample holder 10, an adjustable light source device 20 and a receiving assembly 30 disposed on the substrate.
Wherein, the sample rack 10 is provided with a plurality of cuvette slots 11 at intervals along the transverse direction, each cuvette slot 11 can be inserted to accommodate one cuvette 60, and the cuvette 60 is used for accommodating a sample to be detected and a chemical reagent reacting with the sample; and the sample rack 10 is provided with a first light through hole and a second light through hole which are opposite to each other on the front side wall and the rear side wall of each cuvette slot 11.
The adjustable light source device 20 and the receiving assembly 30 are respectively disposed on the front and rear sides of the sample rack 10, and the adjustable light source device 20 and the receiving assembly 30 can be respectively moved to a position opposite to each cuvette 60 along the lateral direction under the action of the first driving mechanism 40 and the second driving mechanism 50, so that the sample in each cuvette 60 can be detected and analyzed through the interaction of the adjustable light source device 20 and the receiving assembly 30.
It should be noted that, the first driving mechanism 40 is connected to the first base 21, and drives the first base 21 to move laterally and simultaneously drives the second base 22 to move together; the first light source 25A and the second light source 25B on the two bases may be LED light sources, laser diodes or halogen lamps, and the receiving assembly 30 includes a third base connected to the second driving mechanism 50, and a detection head disposed on a side of the third base facing the sample rack; the detection head is a spectrometer or a silicon photocell, and can receive the light emitted by the first light source 25A or the second light source 25B, convert the received light into an electrical signal according to the received light, and send the electrical signal to the control unit to obtain the content parameter of the required detection substance.
The foregoing description is only of the preferred embodiments of the present invention and is not intended to limit the scope of the invention, and all equivalent structural changes made by the description of the present invention and the accompanying drawings or direct/indirect application in other related technical fields are included in the scope of the invention.
Claims (4)
1. A tunable light source apparatus for a biochemical analyzer, comprising:
the device comprises a first base, wherein at least one first light path channel is horizontally arranged between the front wall and the rear wall of the first base, a first lens is arranged at the front end of the first light path channel, and a first light source is arranged at the rear end of the first light path channel;
the second base is arranged at one end of the first base in parallel along the transverse direction, can rotate around a rotating shaft relative to the first base and extends along the transverse direction along the axial direction of the rotating shaft; at least one second light path channel is arranged between the front wall and the rear wall of the second base, a second lens is arranged at the front end of the second light path channel, and a second light source is arranged at the rear end of the second light path channel; the irradiation angle of the second light path channel is adjusted through the rotation angle of the second base;
a limiting piece is arranged between the first base and the second base so as to limit the rotation angle of the second base;
each first light source and each second light source are respectively arranged at the rear ends of the corresponding first light path channel and the corresponding second light path channel through a light source mounting seat and a connecting pipe, one end of each light source mounting seat is provided with a light source mounting hole, the other end of each light source mounting seat is provided with a communication hole connected with the light source mounting hole, one end of each connecting pipe is fixedly inserted into the corresponding communication hole in a plugging manner, the other end of each connecting pipe is fixedly inserted into the rear end of the corresponding first light path channel or the corresponding second light path channel in a plugging manner, and the central axis of each connecting pipe is provided with an optical fiber penetrating through the two ends of each connecting pipe;
the rear end of the first base corresponds to each first light path channel and is provided with a first locking screw hole which is vertically communicated with the first light path channel, the rear end of the second base corresponds to each second light path channel and is provided with a second locking screw hole which is vertically communicated with the second light path channel, the light source mounting seat corresponds to each communication hole and is provided with a third locking screw hole which is vertically communicated with the communication hole, one end of the connecting pipe is fixed with the light source mounting seat through the cooperation of the locking screw and each locking screw hole, and the other end of the connecting pipe is fixed with the first base or the second base.
2. The adjustable light source device for biochemical analyzer according to claim 1, wherein the second base is provided with an arc slide hole penetrating transversely, and the center of the arc slide hole is located on the axis of the rotating shaft;
the limiting piece is a limiting screw, a threaded hole extending transversely is formed in the end face, facing the second base, of the first base, the limiting screw penetrates through the arc-shaped sliding hole to be connected into the threaded hole, and the second base is fixed to the first base.
3. The adjustable light source device for a biochemical analyzer according to claim 1, wherein a light source mounting plate is provided at one end of each light source mounting seat corresponding to the light source mounting hole for fixing the first light source or the second light source in the light source mounting hole.
4. The adjustable light source device for biochemical analyzer according to claim 1, wherein a lens mounting hole is formed at a front end of each of the first and second optical path channels, a lens mounting plate is respectively provided at a front end of the first and second bases corresponding to each of the lens mounting holes, the first and second lenses are fixed in the lens mounting holes of the corresponding first and second optical path channels, and a through hole opposite to the lens mounting hole is formed in each lens mounting plate.
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CN201711430777.1A CN108120683B (en) | 2017-12-26 | 2017-12-26 | Adjustable light source device for biochemical analyzer |
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CN201711430777.1A CN108120683B (en) | 2017-12-26 | 2017-12-26 | Adjustable light source device for biochemical analyzer |
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CN108120683B true CN108120683B (en) | 2024-02-09 |
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CN112326606B (en) * | 2020-09-11 | 2022-05-10 | 广州万孚生物技术股份有限公司 | In-vitro diagnosis and analysis system, optical detection device and motion disc module |
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JP4774157B2 (en) * | 2000-04-13 | 2011-09-14 | 株式会社リコー | Multi-beam light source device and optical scanning device |
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EP1998167A2 (en) * | 2007-06-01 | 2008-12-03 | Samsung Electronics Co., Ltd. | Fluorescence detecting module for microreaction and fluorescence detecting system having the same |
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