CN108101842A - A kind of preparation method of 2- hydroxyls -4- carboxyl quinolines - Google Patents
A kind of preparation method of 2- hydroxyls -4- carboxyl quinolines Download PDFInfo
- Publication number
- CN108101842A CN108101842A CN201711469792.7A CN201711469792A CN108101842A CN 108101842 A CN108101842 A CN 108101842A CN 201711469792 A CN201711469792 A CN 201711469792A CN 108101842 A CN108101842 A CN 108101842A
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- CN
- China
- Prior art keywords
- acetic acid
- carboxyl
- glacial acetic
- preparation
- quinolines
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/50—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 4
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Description
Claims (10)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201711469792.7A CN108101842B (en) | 2017-12-29 | 2017-12-29 | Preparation method of 2-hydroxy-4-carboxyquinoline |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
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CN201711469792.7A CN108101842B (en) | 2017-12-29 | 2017-12-29 | Preparation method of 2-hydroxy-4-carboxyquinoline |
Publications (2)
Publication Number | Publication Date |
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CN108101842A true CN108101842A (en) | 2018-06-01 |
CN108101842B CN108101842B (en) | 2021-04-30 |
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Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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CN201711469792.7A Active CN108101842B (en) | 2017-12-29 | 2017-12-29 | Preparation method of 2-hydroxy-4-carboxyquinoline |
Country Status (1)
Country | Link |
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CN (1) | CN108101842B (en) |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20140075082A (en) * | 2012-12-10 | 2014-06-19 | 주식회사 이큐스앤자루 | Dihydroquinoline derivatives, preparation method thereof and pharmaceutically composition containing the same as an active ingredient for preventing or treatment of disease by influenza A virus |
CN104302624A (en) * | 2012-04-10 | 2015-01-21 | 邓迪大学 | Anti-malarial agents |
-
2017
- 2017-12-29 CN CN201711469792.7A patent/CN108101842B/en active Active
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104302624A (en) * | 2012-04-10 | 2015-01-21 | 邓迪大学 | Anti-malarial agents |
KR20140075082A (en) * | 2012-12-10 | 2014-06-19 | 주식회사 이큐스앤자루 | Dihydroquinoline derivatives, preparation method thereof and pharmaceutically composition containing the same as an active ingredient for preventing or treatment of disease by influenza A virus |
Non-Patent Citations (1)
Title |
---|
KEN S. FELDMAN ET AL.: "Synthesis of the pentacyclic core of lihouidine", 《TETRAHEDRON LETTERS》 * |
Also Published As
Publication number | Publication date |
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CN108101842B (en) | 2021-04-30 |
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Legal Events
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PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
GR01 | Patent grant | ||
GR01 | Patent grant | ||
PE01 | Entry into force of the registration of the contract for pledge of patent right | ||
PE01 | Entry into force of the registration of the contract for pledge of patent right |
Denomination of invention: A preparation method of 2-hydroxy-4-carboxyquinoline Effective date of registration: 20220616 Granted publication date: 20210430 Pledgee: Shandong Pingyuan Rural Commercial Bank Co.,Ltd. Pledgor: SHANDONG CHENGHUI SHUANGDA PHARMACEUTICAL CO.,LTD. Registration number: Y2022980007784 |
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PC01 | Cancellation of the registration of the contract for pledge of patent right | ||
PC01 | Cancellation of the registration of the contract for pledge of patent right |
Date of cancellation: 20230726 Granted publication date: 20210430 Pledgee: Shandong Pingyuan Rural Commercial Bank Co.,Ltd. Pledgor: SHANDONG CHENGHUI SHUANGDA PHARMACEUTICAL CO.,LTD. Registration number: Y2022980007784 |