CN108096706A - A kind of retina prosthese with multiple stimulation components - Google Patents

A kind of retina prosthese with multiple stimulation components Download PDF

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Publication number
CN108096706A
CN108096706A CN201810044189.2A CN201810044189A CN108096706A CN 108096706 A CN108096706 A CN 108096706A CN 201810044189 A CN201810044189 A CN 201810044189A CN 108096706 A CN108096706 A CN 108096706A
Authority
CN
China
Prior art keywords
component
multiple stimulation
eyeball
components according
stimulation components
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201810044189.2A
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Chinese (zh)
Inventor
杨佳威
陈南
张臣
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hagnzhou Warm Caramel Core Electronic Technology Co Ltd
Hangzhou Nanochap Electronics Co Ltd
Original Assignee
Hagnzhou Warm Caramel Core Electronic Technology Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hagnzhou Warm Caramel Core Electronic Technology Co Ltd filed Critical Hagnzhou Warm Caramel Core Electronic Technology Co Ltd
Priority to CN201810044189.2A priority Critical patent/CN108096706A/en
Publication of CN108096706A publication Critical patent/CN108096706A/en
Pending legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36046Applying electric currents by contact electrodes alternating or intermittent currents for stimulation of the eye
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/14Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/05Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/0526Head electrodes
    • A61N1/0543Retinal electrodes

Abstract

The present invention relates to medical instruments fields, specifically belong to a kind of retina prosthese with multiple stimulation components, including the stimulation component being implanted to inside eyeball tissue and it is arranged on the episcleral communication part of eyeball tissue outer wall, component is stimulated to include substrate and the multiple stimulating electrodes being arranged in substrate, communication part includes packaging body and coupling coil, it is multiple to stimulate component, multiple stimulation components are reasonably distributed according to the construction of macular area on macular area and its enclosure region, each stimulate is connected with chip on component, it is brought together and is then attached on external communication component by chip wiring line, effect of stimulation is good, wiring is convenient.

Description

A kind of retina prosthese with multiple stimulation components
Technical field
The invention belongs to medical instruments fields, relate in particular to a kind of retina prosthese with multiple stimulation components.
Background technology
Application of the people to microelectrode, is typically implanted to animal or patient's body, by loading telecommunications by microelectrode It number is studied to stimulate or inhibit nervous activity or nervous activity is converted to electric signal using microelectrode records. In artificial retina, be frequently necessary to by microelectrode be implanted to animal or human eyeball's organization internal human eyeball is organized into It assassinates and swashs patient is helped to improve eyesight, but since human body retina is covered on entire eyeball, integrally there are certain radian, It is difficult still covering well if going to stimulate only with a stimulating electrode or expanding the area of single stimulating chip merely Retina whole region (fringe region electrode can not come into full contact with retina neural), effect of stimulation can give a discount;It passes simultaneously The stimulating electrode of system generally only acts on macula retinae area, does not carry out electrode stimulating with exterior domain to macular area, so suffers from The field-of-view angle that person recovers is also smaller, can not realize the effect for recovering functional vision.
The content of the invention
The present invention is intended to provide a kind of tool can cover entire retinal area, the good retina prosthese of effect of stimulation, this hair The scheme of bright use is as follows:A kind of retina prosthese with multiple stimulation components, which is characterized in that including being implanted to eyeball group It knits internal stimulation component and is arranged on the episcleral communication part of eyeball tissue outer wall, it is described to stimulate component to be multiple, it is multiple Stimulating components distribution, the stimulation component includes substrate and is arranged on the substrate in human eyeball's macular area and its near zone On multiple stimulating electrodes, the communication part include packaging body and coupling coil, it is the multiple stimulation component connected by signal Wiring is connected through eyewall with communication part on eyeball tissue outer wall.
Preferably, the first processing chip is provided in the communication part, is also set up on each stimulation component There is second processing chip, the second processing chip and the substrate link together.
Preferably, also it is covered with chip package lid on the second processing chip, the chip package lid will be at second Manage chip sealing.
Preferably, the stimulating electrode on each stimulation component is connected with second processing chip, and second processing chip passes through Pad in substrate picks out signal connecting line.
Preferably, multiple signal connecting lines stimulated on components are gathered together to form a winding displacement, and the winding displacement is from eyeball It is connected internally on the episcleral communication part of eyeball tissue outer wall.
Preferably, the multiple stimulation component is distributed according to the cambered surface structure of human eyeball's macular area and its near zone.
Preferably, the density of the stimulating electrode on the multiple stimulation component is not exactly the same.Component electrode assembly it is close Degree can be adjusted according to the region that it is specifically covered and set, while stimulate the size of motor that can also change.
Preferably, the packaging body in the communication part and coupling coil are bundled together by silica gel, and silica gel, which is formed, to be connected Tape splicing, communication part form a closed loop by connect band and are fixed on human eyeball's tissue.
Preferably, the communication part or connect band position are provided with suture mouth, the suture mouth is used in implantation Retina prosthese is sewn on eyeball tissue.
Preferably, the cross section of the winding displacement is in " flat ".
Preferably, the winding displacement rotates in the shape of a spiral picks out.
Beneficial effects of the present invention:Macular area of the present invention inside patient's eyeball tissue and its nearby on be provided with it is multiple Stimulate component, it is multiple stimulation components be reasonably distributed according to macular area and its construction of enclosure region, stimulate component density and Size can be arranged to differ according to stimulated zone difference, and effect of stimulation is good.Meanwhile each stimulate is connected with core on component Piece is brought together by signal connecting line and is then attached on external communication component, and it is few to pick out connecting line quantity, operation wound It is small.
Description of the drawings
Fig. 1 is schematic structural view of the invention;
Fig. 2 is moderate stimulation component structure diagram of the present invention;
Fig. 3 is this communication part structure diagram;
Fig. 4 is multiple stimulation component installation structure schematic diagrames.
Wherein 1 is stimulates component, and 2 be communication part, and 21 be packaging body, and 22 be coupling coil, and 23 be connect band, and 24 be seam It heals up, 3 be substrate, and 4 be stimulating electrode, and 5 be second processing chip, and 6 be chip package lid, and 7 be winding displacement, and 71 connect for signal Line, 8 be eyeball tissue.
Specific embodiment
In order to facilitate the understanding of the present invention, it is described below in conjunction with the accompanying drawings:
As shown in Figs 1-4, the present invention provides a kind of retina prosthese with multiple stimulation components, including being implanted to Stimulation component 1 inside eyeball tissue and the episcleral communication part 2 of eyeball tissue outer wall is arranged on, stimulates component 1 to be multiple, Multiple stimulation components 1 are distributed in human body sclera macular area and its near zone, multiple shapes for stimulating component 1 according to eyeball macular area Shape is distributed.
In general, organize macular area and near zone can be there are certain radian, in order to fully stimulate eye in human eyeball Ball tissue, multiple retinas stimulate component 1 that can be distributed according to its construction features in cambered surface, component 1 are stimulated not only to only act upon Huang On macular area, the region near macular area can also be stimulated.
Each multiple stimulating electrodes 4 that component 1 is stimulated to include substrate 3 and be arranged in substrate, communication part 2 include encapsulation Body 21 and coupling coil 22, multiple stimulating electrodes 1 pass through communication group on eyewall and eyeball tissue outer wall by signal connecting line 71 Part 2 connects.
Since each stimulating electrode 1 is required for picking out signal connecting line 71, multiple stimulating electrodes are intended to pick out more More signal connecting lines, when 71 quantity of signal connecting line is excessive, picking out the diameter of circuit will become larger, to people in implantation process The wound of body can also increase, and in order to overcome this defect, each stimulate on component be additionally provided with second processing core in the present invention Piece 5, second processing chip 5 and substrate 3 link together, and 5, second processing core is realized first and the connection of stimulating electrode 1, so Circuit is picked out by the pad structure on second processing chip 5 afterwards, the first processing in last and eyeball external communication component Chip (not marked in figure) is connected, and need not pick out connecting line for every stimulating electrode, greatly reduce the number of connecting line Amount.
Multiple signal connecting lines 71 stimulated on component 1 are gathered together to form a winding displacement 7, and the winding displacement 7 is out of eyeball Portion is connected on the episcleral communication part 2 of eyeball tissue outer wall.
The cross section of winding displacement 7 can be in " flat ", and such winding displacement is also " flat to its wound when through wall of eyeball Shape ", the wound of this " flat " are easier to heal.In addition, winding displacement can also become one by way of spiral rotating Root " it is compact " signal connecting line, the signal connecting line diameter is small, and with certain elasticity, during operation to wound wound It is small, and be not easily broken.
In order to avoid tissue fluid penetrates into component internal is stimulated to cause to damage to the second chip 5, on each stimulation component Second processing chip on be also covered with chip package lid 6, which seals second processing chip 5, can so keep away Exempt from tissue fluid penetrate into stimulate component internal chip is caused to damage, in general, chip package cover be provided with metal feedback Logical structure, metal feed through structures inside are connected with pad, and outside is picked out by connecting line, and sealing effect is good.
In stimulating course, since stimulated zone is different, site of action tissue nerve has differences, multiple stimulations The density of stimulating electrode on component is arranged to not exactly the same, and specific apparent size can also be according to practical function region Adjustment.
Packaging body and coupling coil on the communication part outside eyeball are wrapped with one layer of silica gel, and communication part passes through Connect band 23 forms a closed loop and is fixed on human eyeball's tissue, is set in communication part 2 or 23 position of connect band seamed Heal up 24, the suture mouth 24 is used for retina prosthese being sewn on eyeball tissue in implantation.
Above example is only presently preferred embodiments of the present invention, not limiting the present invention, it is noted that Any modification, equivalent substitution, improvement and etc. made within the spirit and principles of the invention are in protection scope of the present invention Within.

Claims (11)

1. a kind of retina prosthese with multiple stimulation components, which is characterized in that including the thorn being implanted to inside eyeball tissue Swash component and be arranged on the episcleral communication part of eyeball tissue outer wall, the stimulation component is multiple, multiple stimulation components point Cloth macular area and its near zone in human eyeball, it is described that component is stimulated to include substrate and on the substrate multiple are set Stimulating electrode, the communication part include packaging body and coupling coil, and the multiple stimulation component passes through signal connecting line and eye Communication part connects on ball tissue outer wall.
2. a kind of retina prosthese with multiple stimulation components according to claim 1, which is characterized in that described logical The first processing chip is provided in news component, second processing chip is additionally provided on component in each stimulate, described second Processing chip and the substrate link together.
3. a kind of retina prostheses with multiple stimulation components according to claim 2, which is characterized in that described the Chip package lid is also covered in two processing chips, the chip package lid seals second processing chip.
4. a kind of retina prosthese with multiple stimulation components according to claim 2, which is characterized in that in each thorn The stimulating electrode swashed on component is connected with second processing chip, and second processing chip is by the pad in substrate by signal connecting line It picks out.
A kind of 5. retina prosthese with multiple stimulation components according to claim 4, which is characterized in that multiple stimulations Signal connecting line on component is gathered together to form a winding displacement, which is connected internally to eyeball tissue outer wall from eyeball and consolidates On communication part on film.
6. a kind of retina prosthese with multiple stimulation components according to any one in claim 1-4, feature It is, the multiple stimulation component is distributed along the cambered surface structure of human eyeball's macular area and its near zone.
7. a kind of retina prosthese with multiple stimulation components according to any one in claim 1-4, feature It is, the density of the stimulating electrode on the multiple stimulation component is not exactly the same.
A kind of 8. retina prosthese with multiple stimulation components according to claim 1, which is characterized in that the communication Packaging body and coupling coil in component are bundled together by silica gel, and communication part forms a closed loop by connect band and fixes In human eyeball's tissue.
9. a kind of retina prosthese with multiple stimulation components according to claim 4, which is characterized in that described logical News component or connect band position are provided with suture mouth, and in implantation, the suture mouth is used for retina prosthese being sewn to eyeball group It knits.
A kind of 10. retina prosthese with multiple stimulation components according to claim 5, which is characterized in that the row The cross section of line is in " flat ".
A kind of 11. retina prosthese with multiple stimulation components according to claim 5, which is characterized in that the row Line rotates in the shape of a spiral to be picked out.
CN201810044189.2A 2018-01-17 2018-01-17 A kind of retina prosthese with multiple stimulation components Pending CN108096706A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201810044189.2A CN108096706A (en) 2018-01-17 2018-01-17 A kind of retina prosthese with multiple stimulation components

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201810044189.2A CN108096706A (en) 2018-01-17 2018-01-17 A kind of retina prosthese with multiple stimulation components

Publications (1)

Publication Number Publication Date
CN108096706A true CN108096706A (en) 2018-06-01

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3586909A1 (en) * 2018-06-22 2020-01-01 Greatbatch Ltd. Implantable pulse generator with multiple suture ports
CN111588984A (en) * 2020-05-27 2020-08-28 微智医疗器械有限公司 Implanted retina electric stimulator and implant thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7003355B1 (en) * 2001-11-20 2006-02-21 Suaning Gregg J Vision prosthesis for the blind and method for implementing same
CN107519575A (en) * 2017-09-26 2017-12-29 杭州暖芯迦电子科技有限公司 A kind of retina prosthese
CN208081664U (en) * 2018-01-17 2018-11-13 杭州暖芯迦电子科技有限公司 A kind of retina prosthese with multiple stimulation components

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7003355B1 (en) * 2001-11-20 2006-02-21 Suaning Gregg J Vision prosthesis for the blind and method for implementing same
CN107519575A (en) * 2017-09-26 2017-12-29 杭州暖芯迦电子科技有限公司 A kind of retina prosthese
CN208081664U (en) * 2018-01-17 2018-11-13 杭州暖芯迦电子科技有限公司 A kind of retina prosthese with multiple stimulation components

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3586909A1 (en) * 2018-06-22 2020-01-01 Greatbatch Ltd. Implantable pulse generator with multiple suture ports
US11331501B2 (en) 2018-06-22 2022-05-17 Greatbatch Ltd. Implantable pulse generator with multiple suture ports
CN111588984A (en) * 2020-05-27 2020-08-28 微智医疗器械有限公司 Implanted retina electric stimulator and implant thereof
CN111588984B (en) * 2020-05-27 2021-02-19 微智医疗器械有限公司 Implanted retina electric stimulator and implant thereof

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