CN108079115B - 一种治疗静脉曲张的中药组合物及其制备方法 - Google Patents
一种治疗静脉曲张的中药组合物及其制备方法 Download PDFInfo
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- CN108079115B CN108079115B CN201810158670.4A CN201810158670A CN108079115B CN 108079115 B CN108079115 B CN 108079115B CN 201810158670 A CN201810158670 A CN 201810158670A CN 108079115 B CN108079115 B CN 108079115B
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Abstract
本发明涉及一种治疗静脉曲张的中药组合物包括外用组分和内服组分。外用内服同时进行,从内到外改善经脉血栓病灶处的血液循环,并有温阳、生肌和解毒功效,改善病灶处的血液微循环障碍,提高毛细血管通透性,恢复下肢经脉瓣膜功能,抑制静脉血栓的形成,从而彻底治愈静脉曲张。本发明的治疗静脉曲张的中药组合物的制备方法,根据外用与内服需求,制定具体工艺,得到药效良好的外用药剂与内服药剂,达到良好的逐瘀、活血、通络、温阳、止痛之功效。
Description
技术领域
本发明属于中药技术领域,具体涉及一种治疗静脉曲张的中药组合物及其制备方法。
背景技术
静脉曲张是静脉系统最常见的疾病,形成的主要原因是先天性血管壁膜比较薄弱或长时间维持相同姿势很少改变,血液积蓄下肢,日积月累破坏静脉瓣膜而产生静脉压过高,是血管突出皮肤表面的症状。其中下静脉曲张在经理10多年的病程后,随着静脉血液的倒流和淤血的情况加重,会导致下肢水肿、小腿皮肤颜色变黑、淤积性皮炎、静脉血栓疼痛甚至溃疡。
静脉曲张目前为止多采用西医治疗,轻者用硬化剂注射,重者只能用手术的方法治疗,单治疗效果都不理想。硬化剂注射易引起静脉血栓形成,从而诱发局部溃疡而形成臁疮;手术治疗易导致下肢循环障碍,产生患肢浮肿,而且容易复发。如果手术不能将曲张的静脉全部剥脱,留下的曲张静脉内可以注射硬化剂,使静脉壁产生无菌性炎症,对壁相互粘着,不再曲张。经多年临床实践,不少病人手术后还会复发,疗效不确切,多次手术也未能治愈。手术法不仅对病人有一定的痛苦,而且费用较高,治愈率很低。药物疗法目前还没有效果较佳的药品。
发明内容
基于以上问题,本发明的其一目的是提供一种治疗静脉曲张的中药组合物。
其二目的是提供一种所述中药组合物的制备方法。
本发明的技术方案为:
本发明提供一种治疗静脉曲张的中药组合物,包括以下重量份组分:
外用组分:红花10-25份、怀牛膝15-30份、透骨草10-30份、灵仙10-30份、伸筋草10-30份、仙人掌20-30份、延胡索10-15份、细辛2-4份、丹参2-3份,生地黄5-10份和鸡血藤10-30份;
内服组分:断续20-30份、怀牛膝20-30份、丹参10-20份、木瓜40-50份、桑枝5-10份、桂枝10-15份、川椒5-10份、石斛10-20份、玄参5-10份、地黄20-30份和酒糟50-60份。
根据本发明的治疗静脉曲张的中药组合物,包括以下重量份组分:
外用组分:红花20份、怀牛膝20份、透骨草20份、灵仙15份、伸筋草15份、仙人掌20份、延胡索12份、细辛3份、丹参3份,生地黄8份和鸡血藤20份;
内服组分:断续25份、怀牛膝20份、丹参10份、木瓜50份、桑枝8份、桂枝15份、川椒10份、石斛15份、玄参10份、地黄30份和酒糟60份。
根据本发明的治疗静脉曲张的中药组合物,内服组分中还包括干姜3-5份和延胡索10-15份。干姜加入,与川椒、木瓜协同作用,加强内服组分的驱寒温阳功效,延胡索加入,与怀牛膝和丹参协同作用,活血化瘀、止痛的作用更好。
根据本发明的治疗静脉曲张的中药组合物,内服组分中还包括细辛10-20份,散寒通窍,止痛功效更好。
根据本发明的治疗静脉曲张的中药组合物,内服组分中还包括枳壳10-15份,枳壳的加入更有利于缓解血栓症状。
根据本发明的治疗静脉曲张的中药组合物,包括以下重量份组分:
外用组分:红花20份、怀牛膝20份、透骨草20份、灵仙15份、伸筋草15份、仙人掌20份、延胡索12份、细辛3份、丹参3份,生地黄8份和鸡血藤20份;
内服组分:断续25份、怀牛膝20份、丹参10份、木瓜50份、桑枝8份、桂枝15份、川椒10份、石斛15份、玄参10份、地黄30份、干姜4份、延胡索12份、细辛15份、枳壳13份和酒糟60份。
所述治疗静脉曲张的中药组合物中部分组分的功效和作用为:
红花:活血化瘀、散湿祛肿、活血通经,祛瘀止痛。
怀牛膝:活血化瘀、强筋骨、逐瘀通经、引血下行。
木瓜:疏筋化湿、平肝舒筋、和胃化湿。
透骨草:舒筋活络、活血止痛。
灵仙:祛风除湿、通络止痛。
伸筋草:祛风除湿、舒筋活络。
干姜:温中散寒、回阳通脉。
延胡索:活血、利气、止痛。
细辛:祛风散寒、通窍止痛。
枳壳:理气宽中,行滞消涨。
丹参:祛瘀止痛,活血通经。
桑枝:祛风湿、利关节。
桂枝:温通经脉、通阳化气。
鸡血藤:活血舒筋、补血、通络。
玄参:凉血滋阴,泻火解毒。
断续:通利血脉、补肝肾、强筋骨。
地黄:清热凉血。
石斛:滋阴清热。
所述外用组分和内用组分均以各自组分辅助作用,起到逐瘀、活血、通络、温阳、止痛之功效。
本发明的治疗静脉曲张的中药组合物的制备方法,包括以下步骤:
(1)制备外用药剂:将外用组分的各原料混合,加入混合物总质量5-8倍的乙醇浓度为80-90%的乙醇溶液进行回流浸提,过滤,得到第一外用组分提取液;将过滤得到的药渣加入药渣质量3-5倍的乙醇浓度为80-90%的乙醇溶液进行回流浸提,过滤,得到第二外用组分提取液;将第一外用组分提取液和第二外用组分提取液混合,减压浓缩去除乙醇溶剂,干燥获得含水率为8-10%的膏剂;将膏剂进行粉碎,得外用药剂;
(2)制备内服药剂:将桂枝、玄参、地黄和石斛与酒糟混合,30-40℃浸泡,过滤,得到酒糟滤液和酒糟滤渣;将酒糟滤渣和其他内服组分混合,加入酒糟滤渣和其他内服组分混合物3-5倍的乙醇浓度为90%的乙醇溶液进行回流浸提,过滤,得到第一内用组分提取液;将过滤后的药渣加入药渣质量2-3倍的乙醇浓度为90%的乙醇溶液进行回流浸提,过滤,得到第二内用组分提取液;将第一内用组分提取液和第二内用组分提取液混合,减压浓缩去除乙醇溶剂,得内用组分混合提取液,将所述酒糟滤液与所述内用组分混合提取液混合,得内服药剂。
以上制备方法,列出了所述中药组合物中,外用组分和内服组分分别制成外用药剂和内服药剂的具体方法。其中内服组分先将桂枝、玄参、地黄和石斛与酒糟混合浸泡,缓解玄参、地黄和石斛的寒性,发挥其解毒功效。其次,以酒糟直接浸泡桂枝、玄参、地黄和石斛得到酒糟滤液,直接与提取得到的内用组分混合提取液混合,供病人直接内服,保留酒糟固有的活血止痛、温中散寒功效。
本发明的治疗静脉曲张的中药组合物的制备方法,在步骤(1)中,第一次回流浸提3-5小时,第二次回流浸提1-2小时;在步骤(2)中,第一次回流浸提2-3小时,第二次回流浸提1-2小时。在步骤(1)中,干燥后的膏剂含水率为8-10%,保证膏剂更加容易粉碎至目的粒径,不粘粘于破碎设备上,造成原料浪费,及清洗不便。
本发明的治疗静脉曲张的中药组合物的制备方法,在步骤(1)中,得到的所述外用药剂的粒径为300-500目。
本发明的治疗静脉曲张的中药组合物的制备方法,在步骤(2)中,浸泡时间为5-7天。
本发明的有益效果为:
本发明的治疗静脉曲张的中药组合物包括外用组分和内服组分。外用内服同时进行,从内到外改善经脉血栓病灶处的血液循环,并有温阳、生肌和解毒功效,改善病灶处的血液微循环障碍,提高毛细血管通透性,恢复下肢经脉瓣膜功能,抑制静脉血栓的形成,从而彻底治愈静脉曲张。
本发明的治疗静脉曲张的中药组合物的制备方法,根据外用与内服需求,制定具体工艺。可以得到药效良好的外用药剂与内服药剂,达到良好的逐瘀、活血、通络、温阳、止痛之功效。
具体实施方式
为使本发明的目的、技术方案和优点更加清楚,下面将对本发明的技术方案进行详细的描述。显然,所描述的实施例仅仅是本发明一部分实施例,而不是全部的实施例。基于本发明中的实施例,本领域普通技术人员在没有做出创造性劳动的前提下所得到的所有其它实施方式,都属于本发明所保护的范围。
以下实施例以1份为1g。
实施例1
本发明的一种治疗静脉曲张的中药组合物,其特征在于,包括以下重量份组分:外用组分:红花20份、怀牛膝20份、透骨草20份、灵仙15份、伸筋草15份、仙人掌20份、延胡索12份、细辛3份、丹参3份,生地黄8份和鸡血藤20份;
内服组分:断续25份、怀牛膝20份、丹参10份、木瓜50份、桑枝8份、桂枝15份、川椒10份、石斛15份、玄参10份、地黄30份和酒糟60份。
所述的治疗静脉曲张的中药组合物的制备方法,其特征在于,包括以下步骤:
(1)制备外用药剂:将外用组分的各原料混合,加入混合物总质量5-8倍的乙醇浓度为90%的乙醇溶液进行回流浸提3-5小时,过滤,得到第一外用组分提取液;将过滤得到的药渣加入药渣质量3-5倍的乙醇浓度为90%的乙醇溶液进行回流浸提1-2小时,过滤,得到第二外用组分提取液;将第一外用组分提取液和第二外用组分提取液混合,减压浓缩去除乙醇溶剂,干燥获得含水率为8-10%的膏剂;将膏剂进行粉碎后过300-500目筛,得外用药剂;
(2)制备内服药剂:将桂枝、玄参、地黄和石斛与酒糟混合,30-40℃浸泡5-7天,过滤,得到酒糟滤液和酒糟滤渣;将酒糟滤渣和其他内服组分混合,加入酒糟滤渣和其他内服组分混合物3-5倍的乙醇浓度为80%的乙醇溶液进行回流浸提2-3小时,过滤,得到第一内用组分提取液;将过滤后的药渣加入药渣质量2-3倍的乙醇浓度为90%的乙醇溶液进行回流浸提1-2小时,过滤,得到第二内用组分提取液;将第一内用组分提取液和第二内用组分提取液混合,减压浓缩去除乙醇溶剂,得内用组分混合提取液,将所述酒糟滤液与所述内用组分混合提取液混合,得内服药剂。
实施例2
本发明的一种治疗静脉曲张的中药组合物,包括以下重量份组分:
外用组分:红花25份、怀牛膝15份、透骨草30份、灵仙10份、伸筋草30份、仙人掌25份、延胡索15份、细辛2份、丹参2份,生地黄5份和鸡血藤30份;
内服组分:断续20份、怀牛膝30份、丹参15份、木瓜45份、桑枝5份、桂枝10份、川椒5份、石斛20份、玄参8份、地黄25份、干姜3份、延胡索10份和酒糟55份。
所述的治疗静脉曲张的中药组合物的制备方法,其特征在于,包括以下步骤:
(1)制备外用药剂:将外用组分的各原料混合,加入混合物总质量5倍的乙醇浓度为90%的乙醇溶液进行回流浸提5小时,过滤,得到第一外用组分提取液;将过滤得到的药渣加入药渣质量3倍的乙醇浓度为80%的乙醇溶液进行回流浸提2小时,过滤,得到第二外用组分提取液;将第一外用组分提取液和第二外用组分提取液混合,减压浓缩去除乙醇溶剂,干燥获得含水率为8%的膏剂;将膏剂进行粉碎后过500目筛,得外用药剂;
(2)制备内服药剂:将桂枝、玄参、地黄和石斛与酒糟混合,30℃浸泡7天,过滤,得到酒糟滤液和酒糟滤渣;将酒糟滤渣和其他内服组分混合,加入酒糟滤渣和其他内服组分混合物3倍的乙醇浓度为90%的乙醇溶液进行回流浸提3小时,过滤,得到第一内用组分提取液;将过滤后的药渣加入药渣质量2倍的乙醇浓度为90%的乙醇溶液进行回流浸提2小时,过滤,得到第二内用组分提取液;将第一内用组分提取液和第二内用组分提取液混合,减压浓缩去除乙醇溶剂,得内用组分混合提取液,将所述酒糟滤液与所述内用组分混合提取液混合,得内服药剂。
实施例3
本发明的一种治疗静脉曲张的中药组合物,包括以下重量份组分:外用组分:红花10份、怀牛膝30份、透骨草10份、灵仙30份、伸筋草10份、仙人掌30份、延胡索10份、细辛4份、丹参2份,生地黄10份和鸡血藤10份;
内服组分:断续30份、怀牛膝25份、丹参20份、木瓜40份、桑枝10份、桂枝12份、川椒8份、石斛10份、玄参5份、地黄20份、细辛20份和酒糟50份。
所述的治疗静脉曲张的中药组合物的制备方法,其特征在于,包括以下步骤:
(1)制备外用药剂:将外用组分的各原料混合,加入混合物总质量8倍的乙醇浓度为90%的乙醇溶液进行回流浸提3小时,过滤,得到第一外用组分提取液;将过滤得到的药渣加入药渣质量5倍的乙醇浓度为85%的乙醇溶液进行回流浸提1小时,过滤,得到第二外用组分提取液;将第一外用组分提取液和第二外用组分提取液混合,减压浓缩去除乙醇溶剂,干燥获得含水率为10%的膏剂;将膏剂进行粉碎后过300目筛,得外用药剂;
(2)制备内服药剂:将桂枝、玄参、地黄和石斛与酒糟混合,40℃浸泡5天,过滤,得到酒糟滤液和酒糟滤渣;将酒糟滤渣和其他内服组分混合,加入酒糟滤渣和其他内服组分混合物5倍的乙醇浓度为90%的乙醇溶液进行回流浸提2小时,过滤,得到第一内用组分提取液;将过滤后的药渣加入药渣质量3倍的乙醇浓度为90%的乙醇溶液进行回流浸提1小时,过滤,得到第二内用组分提取液;将第一内用组分提取液和第二内用组分提取液混合,减压浓缩去除乙醇溶剂,得内用组分混合提取液,将所述酒糟滤液与所述内用组分混合提取液混合,得内服药剂。
实施例4
本发明的一种治疗静脉曲张的中药组合物,包括以下重量份组分:外用组分:红花25份、怀牛膝15份、透骨草30份、灵仙10份、伸筋草30份、仙人掌20份、延胡索15份、细辛2份、丹参3份,生地黄5份和鸡血藤30份;
内服组分:断续20份、怀牛膝30份、丹参15份、木瓜45份、桑枝5份、桂枝10份、川椒5份、石斛20份、玄参8份、地黄25份、干姜5份、延胡索15份、细辛10份、枳壳10份和酒糟52份。
所述的治疗静脉曲张的中药组合物的制备方法,包括以下步骤:
(1)制备外用药剂:将外用组分的各原料混合,加入混合物总质量6倍的乙醇浓度为90%的乙醇溶液进行回流浸提4小时,过滤,得到第一外用组分提取液;将过滤得到的药渣加入药渣质量4倍的乙醇浓度为90%的乙醇溶液进行回流浸提1小时,过滤,得到第二外用组分提取液;将第一外用组分提取液和第二外用组分提取液混合,减压浓缩去除乙醇溶剂,干燥获得含水率为9%的膏剂;将膏剂进行粉碎后过400目筛,得外用药剂;
(2)制备内服药剂:将桂枝、玄参、地黄和石斛与酒糟混合,35℃浸泡6天,过滤,得到酒糟滤液和酒糟滤渣;将酒糟滤渣和其他内服组分混合,加入酒糟滤渣和其他内服组分混合物4倍的乙醇浓度为85%的乙醇溶液进行回流浸提2小时,过滤,得到第一内用组分提取液;将过滤后的药渣加入药渣质量2倍的乙醇浓度为90%的乙醇溶液进行回流浸提1小时,过滤,得到第二内用组分提取液;将第一内用组分提取液和第二内用组分提取液混合,减压浓缩去除乙醇溶剂,得内用组分混合提取液,将所述酒糟滤液与所述内用组分混合提取液混合,得内服药剂。
实施例5
本发明的一种治疗静脉曲张的中药组合物,包括以下重量份组分:外用组分:外用组分:红花20份、怀牛膝20份、透骨草20份、灵仙15份、伸筋草15份、仙人掌20份、延胡索12份、细辛3份、丹参3份,生地黄8份和鸡血藤20份;
内服组分:断续25份、怀牛膝20份、丹参10份、木瓜50份、桑枝8份、桂枝15份、川椒10份、石斛15份、玄参10份、地黄30份、干姜4份、延胡索12份、细辛15份、枳壳13份和酒糟60份。
所述的治疗静脉曲张的中药组合物的制备方法,包括以下步骤:
(1)制备外用药剂:将外用组分的各原料混合,加入混合物总质量6倍的乙醇浓度为90%的乙醇溶液进行回流浸提3小时,过滤,得到第一外用组分提取液;将过滤得到的药渣加入药渣质量5倍的乙醇浓度为90%的乙醇溶液进行回流浸提2小时,过滤,得到第二外用组分提取液;将第一外用组分提取液和第二外用组分提取液混合,减压浓缩去除乙醇溶剂,干燥获得含水率为10%的膏剂;将膏剂进行粉碎后过500目筛,得外用药剂;
(2)制备内服药剂:将桂枝、玄参、地黄和石斛与酒糟混合,40℃浸泡5天,过滤,得到酒糟滤液和酒糟滤渣;将酒糟滤渣和其他内服组分混合,加入酒糟滤渣和其他内服组分混合物5倍的乙醇浓度为90%的乙醇溶液进行回流浸提2小时,过滤,得到第一内用组分提取液;将过滤后的药渣加入药渣质量2倍的乙醇浓度为90%的乙醇溶液进行回流浸提1小时,过滤,得到第二内用组分提取液;将第一内用组分提取液和第二内用组分提取液混合,减压浓缩去除乙醇溶剂,得内用组分混合提取液,将所述酒糟滤液与所述内用组分混合提取液混合,得内服药剂。
实施例6
本发明的一种治疗静脉曲张的中药组合物,包括以下重量份组分:外用组分:红花20份、怀牛膝20份、透骨草20份、灵仙20份、伸筋草20份、仙人掌25份、延胡索10份、细辛2份、丹参3份、生地黄5份和鸡血藤10份;
内服组分:断续25份、怀牛膝25份、丹参10份、木瓜40份、桑枝10份、桂枝10份、川椒10份、石斛10份、玄参10份、地黄20份、枳壳15份和酒糟60份。
所述的治疗静脉曲张的中药组合物的制备方法,包括以下步骤:
(1)制备外用药剂:将外用组分的各原料混合,加入混合物总质量8倍的乙醇浓度为90%的乙醇溶液进行回流浸提5小时,过滤,得到第一外用组分提取液;将过滤得到的药渣加入药渣质量5倍的乙醇浓度为90%的乙醇溶液进行回流浸提2小时,过滤,得到第二外用组分提取液;将第一外用组分提取液和第二外用组分提取液混合,减压浓缩去除乙醇溶剂,干燥获得含水率为10%的膏剂;将膏剂进行粉碎后过350目筛,得外用药剂;
(2)制备内服药剂:将桂枝、玄参、地黄和石斛与酒糟混合,40℃浸泡5天,过滤,得到酒糟滤液和酒糟滤渣;将酒糟滤渣和其他内服组分混合,加入酒糟滤渣和其他内服组分混合物5倍的乙醇浓度为90%的乙醇溶液进行回流浸提2小时,过滤,得到第一内用组分提取液;将过滤后的药渣加入药渣质量3倍的乙醇浓度为90%的乙醇溶液进行回流浸提1小时,过滤,得到第二内用组分提取液;将第一内用组分提取液和第二内用组分提取液混合,减压浓缩去除乙醇溶剂,得内用组分混合提取液,将所述酒糟滤液与所述内用组分混合提取液混合,得内服药剂。
实验例
1、征集患有下肢静脉曲张的患者100例,其中男58例,女42例。随机分为5组,每组25人。五组志愿者在年龄、性别、病情轻重方便比较差异无统计学意义,具有可比性。
2、治疗方法
5组分别选用实施例1、实施例2、实施例3、实施例4和实施例6的中药组合物。将由外用组分制得的外用药剂100g用沸水冲开,待10分钟后,清洗患处,每次30分钟,每日一次;将内服组分制得的内服药剂每次饮用50g,每日3次,以上以2周为一个疗程。
3、疗效评定
痊愈:症状完全消失;显效:症状基本消除;有效:症状减轻;无效:症状无明显变化。
4、治疗结果
以痊愈、显效和有效的总数为总有效率。
表1为实验各组的治疗情况对比
表1
组别 | 痊愈/人 | 显效 | 有效 | 无效 | 总有效/% |
实施例1 | 12 | 3 | 3 | 2 | 90 |
实施例2 | 14 | 2 | 3 | 1 | 95 |
实施例3 | 14 | 3 | 2 | 1 | 95 |
实施例4 | 15 | 2 | 3 | 0 | 100 |
实施例6 | 13 | 2 | 3 | 2 | 90 |
由表1可以看出5个实施例的志愿者的治疗情况的总有效率均在90%以上。以本发明的中药组合物治疗静脉曲张效果好,疗效确切。
以上所述,仅为本发明的具体实施方式,但本发明的保护范围并不局限于此,任何熟悉本技术领域的技术人员在本发明揭露的技术范围内,可轻易想到变化或替换,都应涵盖在本发明的保护范围之内。因此,本发明的保护范围应以所述权利要求的保护范围为准。
Claims (5)
1.一种治疗静脉曲张的中药组合物,其特征在于,由以下重量份组分制成:
外用组分:红花10-25份、怀牛膝15-30份、透骨草10-30份、灵仙10-30份、伸筋草10-30份、仙人掌20-30份、延胡索10-15份、细辛2-4份、丹参2-3份,生地黄5-10份和鸡血藤10-30份;
内服组分:续断20-30份、怀牛膝20-30份、丹参10-20份、木瓜40-50份、桑枝5-10份、桂枝10-15份、川椒5-10份、石斛10-20份、玄参5-10份、地黄20-30份、干姜3-5份、延胡索10-15份、细辛10-20份、枳壳10-15份、酒糟50-60份;
所述的治疗静脉曲张的中药组合物的制备方法,包括以下步骤:
(1)制备外用药剂:将外用组分的各原料混合,加入混合物总质量5-8倍的乙醇浓度为80-90%的乙醇溶液进行回流浸提,过滤,得到第一外用组分提取液;将过滤得到的药渣加入药渣质量3-5倍的乙醇浓度为80-90%的乙醇溶液进行回流浸提,过滤,得到第二外用组分提取液;将第一外用组分提取液和第二外用组分提取液混合,减压浓缩去除乙醇溶剂,干燥获得含水率为8-10%的膏剂,将膏剂进行粉碎,得外用药剂;
(2)制备内服药剂:将桂枝、玄参、地黄和石斛与酒糟混合,30-40℃浸泡,过滤,得到酒糟滤液和酒糟滤渣;将酒糟滤渣和其他内服组分混合,加入酒糟滤渣和其他内服组分混合物3-5倍的乙醇浓度为90%的乙醇溶液进行回流浸提,过滤,得到第一内用组分提取液;将过滤后的药渣加入药渣质量2-3倍的乙醇浓度为90%的乙醇溶液进行回流浸提,过滤,得到第二内用组分提取液;将第一内用组分提取液和第二内用组分提取液混合,减压浓缩去除乙醇溶剂,得内用组分混合提取液,将所述酒糟滤液与所述内用组分混合提取液混合,得内服药剂。
2.根据权利要求1所述的治疗静脉曲张的中药组合物,其特征在于,由以下重量份组分制成:
外用组分:红花20份、怀牛膝20份、透骨草20份、灵仙15份、伸筋草15份、仙人掌20份、延胡索12份、细辛3份、丹参3份,生地黄8份和鸡血藤20份;
内服组分:续断25份、怀牛膝20份、丹参10份、木瓜50份、桑枝8份、桂枝15份、川椒10份、石斛15份、玄参10份、地黄30份、干姜4份、延胡索12份、细辛15份、枳壳13份、酒糟60份。
3.根据权利要求1所述的治疗静脉曲张的中药组合物,其特征在于,在步骤(1)中,第一次回流浸提3-5小时,第二次回流浸提1-2小时;在步骤(2)中,第一次回流浸提2-3小时,第二次回流浸提1-2小时。
4.根据权利要求1所述的治疗静脉曲张的中药组合物,其特征在于,在步骤(1)中,得到的所述外用药剂的粒径为300-500目。
5.根据权利要求1所述的治疗静脉曲张的中药组合物,其特征在于,在步骤(2)中,浸泡时间为5-7天。
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