CN108078889A - A kind of hand cleanser and preparation method - Google Patents
A kind of hand cleanser and preparation method Download PDFInfo
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- CN108078889A CN108078889A CN201711305307.2A CN201711305307A CN108078889A CN 108078889 A CN108078889 A CN 108078889A CN 201711305307 A CN201711305307 A CN 201711305307A CN 108078889 A CN108078889 A CN 108078889A
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- vitamin
- hand cleanser
- essential oil
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/987—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/365—Hydroxycarboxylic acids; Ketocarboxylic acids
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/10—Washing or bathing preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/52—Stabilizers
- A61K2800/524—Preservatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/596—Mixtures of surface active compounds
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- Birds (AREA)
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Abstract
The invention discloses a kind of hand cleanser and preparation methods, belong to daily chemical product technical field.Include the raw material components of following mass fraction：3~5 parts of 45~50 parts of lanolin glycerine, 8~15 parts of surfactant, 5~10 parts of ethyl alcohol, 3~8 parts of vitamin, 5~8 parts of essential oil and pearl powder, remaining is deionized water, further include citric acid, cosurfactant and emulsifier, by lanolin glycerine, surfactant, cosurfactant, vitamin, pearl powder, deionized water and emulsifier after weighing, being stirred and heat, add ethyl alcohol and essential oil, it stirs to uniformly mixed, pH value is finally adjusted to faintly acid, it packs to get final product.This product can not only realize effective decontamination purpose, and easily rinse well in a short time, and hand skin is maintained to be in comfortable, pure and fresh state, there is fabulous skin care effect.
Description
Technical field
Present invention relates particularly to a kind of hand cleanser and preparation methods, belong to daily chemical product technical field.
Background technology
Hand-washing article belongs to one kind of skin cleaner, and in China, very long one period, people are mostly used fertilizer in the past（It is fragrant）Soap,
Washing powder, gasoline, liquid detergent etc. are washed one's hands, although with good dirt-removing power, fertilizer（It is fragrant）Soap easily slides, meets when in use
Water and high temperature can soften and consume naturally, larger to the irritation of skin, wash rear skin and drying, crackle, decortication etc. often occur now
As and dirt dirt-removing power of other hand-washing articles to some special work post operating personnel on hand is very undesirable, especially gasoline
Etc. oils, due to toxicity, the body that can be given people brings harm, especially easily contamination dirt on hand and bacterium, becomes two
Secondary source of pollution.The transformation of mass consumption idea makes hand cleanser be increasingly becoming the substitute of traditional hand-washing article in recent years, extensively should
For public arenas such as family, hotel, restaurant, airport, station and hospitals.Hand cleanser has that performance is mild, does not stimulate skin, makes
With convenient, hard water resistance, easy cleaning, foaming abundancy and the features such as rear skin lubrication sense is good is washed, and sanitation and hygiene, it is easily stored.Especially
It uses bottle pump head squash type taken amount, avoids cross-infection when different crowd uses, thus is subject to consumers in general's
Popular welcome.With the maturation of hand cleanser production technology and the popularization in market, consumer has hand cleanser higher expectation, removes
Outside the basic performance of cleaning hand dirt, it is also called to have more functional, there have been the species of a variety of hand cleanser.
With being on the increase for hand cleanser species, people also constantly require hand cleanser performance.And washing currently on the market
Hand liquid there is a problem as follows：1. pair oil stain dirt-removing power wretched insufficiency；2. after washing one's hands, being not easy to rinse well, and cause hand
Skin is not easy to do, even more so that hand skin is too sliding；3. after placing a period of time, qualitative change easily occurs, the smell is awful for appearance, matter
Ground corruption.Therefore it is badly in need of a kind of hand cleanser of suitable people.
The content of the invention
Present invention seek to address that prior art problem, and propose a kind of hand cleanser and preparation method.Using this hand cleanser,
It not only realizes effective decontamination purpose, but also using after this hand cleanser, is easily rinsed well in the short time, hand skin is maintained to be in and is relaxed
Suitable, pure and fresh state；Meanwhile using essential oil, fragrance is eliminated, after washing one's hands, hand stays lingering fragrance, and essential oil has fabulous skin care effect.
In order to realize above-mentioned technical purpose, following technical solution is proposed：
A kind of hand cleanser includes the raw material components of following mass fraction：45~50 parts of lanolin glycerine, surfactant 8~15
Part, 5~10 parts of ethyl alcohol, 3~8 parts of vitamin, 5~8 parts of essential oil and 3~5 parts of pearl powder, remaining is deionized water.
Preferably, the raw material components of following mass fraction are included：48 parts of lanolin glycerine, 12 parts of surfactant, ethyl alcohol 7
Part, 6 parts of vitamin, 7 parts of essential oil and 4 parts of pearl powder, remaining is deionized water.
Citric acid, cosurfactant and emulsifier are further included in hand cleanser.
The surfactant includes one kind or arbitrary two or more mixing in AES, AESA, SAS and AOS.
The cosurfactant includes Cocoalkyl amido propyl betaine, coconut monoethanol amide and ethylene glycol
One kind or arbitrary two or more mixing in distearate.
The vitamin includes one kind or arbitrary two or more mixing in vitamin B, vitamin C and vitamin E.
The extraction of essential oil raw material include a kind of in rose, lemon, aloe, chamomile, honeysuckle, Chinese grooseberry and tea seed
Or arbitrary two or more mixing.
One kind is washed one's hands liquid and preparation method thereof, is included the following steps：
A. after weighing lanolin glycerine, surfactant, cosurfactant, vitamin, pearl powder by metering respectively, put
In in container, deionized water then is being added in being stirred during emulsifier, and 25~30min is heated under the conditions of 55~65 DEG C, it is quiet
30~60min is put, it is spare；
B. ethyl alcohol and essential oil are added in gained mixture into step A, stirred to being uniformly mixed, it is spare；
C. citric acid is added in gained mixture into step B, and adjusts product pH value to faintly acid, packed to get end
Product.
The mixing speed is 350~400 r/min.
The hand cleanser pH value is 4.3-6.4.
Using the technical program, the advantageous effects brought are：
In the present invention, this product can realize effective decontamination by the collective effect of surfactant and cosurfactant
Purpose, and easily rinse well in a short time.Ethyl alcohol improves clean effect, while is a kind of organic solvent, common with emulsifier
Improve hand cleanser quality.Vitamin, essential oil and pearl powder promote hand skin to be in comfortable, pure and fresh state；Meanwhile it provides
Aromatic odor, hand stay lingering fragrance；And with good skin care effect, promote that skin is fine and smooth, soft and smooth and moist state；
In the present invention, citric acid is not only used as preservative, and can be used for adjusting pH value, meanwhile, citric acid belongs to tartaric acid
One kind accelerates cutin update, and the update of cutin contributes to the peeling of the middle melanin of skin, and the receipts of pore are thin, the dissolving of blackhead
Deng；
In the present invention, hand cleanser pH value is 4.3-6.4, and the pH value is close with human skin pH value, in order to avoid human skin is made
Into stimulation.
Specific embodiment
It is clearly and completely described below by the technical solution in the embodiment of the present invention, it is clear that described reality
The part of the embodiment that example is only the present invention is applied, instead of all the embodiments.Based on the embodiments of the present invention, this field is general
All other embodiment that logical technical staff is obtained without making creative work belongs to what the present invention protected
Scope.
Embodiment 1
A kind of hand cleanser includes the raw material components of following mass fraction：45 parts of lanolin glycerine, 8 parts of surfactant, ethyl alcohol 5
Part, 3 parts of vitamin, 5 parts of essential oil and 3 parts of pearl powder, remaining is deionized water.
Citric acid, cosurfactant and emulsifier are further included in hand cleanser.
The surfactant is AES.
The cosurfactant is the mixing of Cocoalkyl amido propyl betaine and coconut monoethanol amide.
The vitamin is vitamin B.
The essential oil is Rosa Damascana.
Embodiment 2
A kind of hand cleanser includes the raw material components of following mass fraction：48 parts of lanolin glycerine, 12 parts of surfactant, ethyl alcohol 7
Part, 6 parts of vitamin, 7 parts of essential oil and 4 parts of pearl powder, remaining is deionized water.
Citric acid, cosurfactant and emulsifier are further included in hand cleanser.
The surfactant is the mixing of SAS and AOS.
The cosurfactant is coconut monoethanol amide.
The vitamin is vitamin E.
The essential oil is tea seed essential oil.
One kind is washed one's hands liquid and preparation method thereof, is included the following steps：
A. after weighing lanolin glycerine, surfactant, cosurfactant, vitamin, pearl powder by metering respectively, put
In in container, deionized water then is being added in being stirred during emulsifier, and 25min is heated under the conditions of 55 DEG C, stands 30min,
It is spare；
B. ethyl alcohol and essential oil are added in gained mixture into step A, stirred to being uniformly mixed, it is spare；
C. citric acid is added in gained mixture into step B, and adjusts product pH value to faintly acid, packed to get end
Product.
The mixing speed is 350 r/min.
The hand cleanser pH value is 4.3.
Embodiment 3
A kind of hand cleanser includes the raw material components of following mass fraction：45 parts of lanolin glycerine, 15 parts of surfactant, ethyl alcohol 5
Part, 8 parts of vitamin, 5 parts of essential oil and 3 parts of pearl powder, remaining is deionized water.
Citric acid, cosurfactant and emulsifier are further included in hand cleanser.
The surfactant is the mixing of SAS and AOS.
The cosurfactant is glycol distearate.
The vitamin is the mixing of vitamin C and vitamin E.
The extraction of essential oil raw material include the mixing of lemon, aloe and chamomile.
One kind is washed one's hands liquid and preparation method thereof, is included the following steps：
A. after weighing lanolin glycerine, surfactant, cosurfactant, vitamin, pearl powder by metering respectively, put
In in container, deionized water then is being added in being stirred during emulsifier, and 25min is heated under the conditions of 65 DEG C, stands 30min,
It is spare；
B. ethyl alcohol and essential oil are added in gained mixture into step A, stirred to being uniformly mixed, it is spare；
C. citric acid is added in gained mixture into step B, and adjusts product pH value to faintly acid, packed to get end
Product.
The mixing speed is 400 r/min.
The hand cleanser pH value is 6.4.
Embodiment 4
A kind of hand cleanser includes the raw material components of following mass fraction：50 parts of lanolin glycerine, 15 parts of surfactant, ethyl alcohol
5 parts of 10 parts, 8 parts of vitamin, 8 parts of essential oil and pearl powder, remaining is deionized water.
Citric acid, cosurfactant and emulsifier are further included in hand cleanser.
The surfactant is AOS.
The cosurfactant is the mixing of Cocoalkyl amido propyl betaine and glycol distearate.
The vitamin is the mixing of vitamin B, vitamin C and vitamin E.
The extraction of essential oil raw material are the mixing of rose, lemon, aloe, chamomile, honeysuckle, Chinese grooseberry and tea seed.
One kind is washed one's hands liquid and preparation method thereof, is included the following steps：
A. after weighing lanolin glycerine, surfactant, cosurfactant, vitamin, pearl powder by metering respectively, put
In in container, deionized water then is being added in being stirred during emulsifier, and 30min is heated under the conditions of 65 DEG C, stands 60min,
It is spare；
B. ethyl alcohol and essential oil are added in gained mixture into step A, stirred to being uniformly mixed, it is spare；
C. citric acid is added in gained mixture into step B, and adjusts product pH value to faintly acid, packed to get end
Product.
The mixing speed is 400 r/min.
The hand cleanser pH value is 4.3-6.4.
Embodiment 5
A kind of hand cleanser includes the raw material components of following mass fraction：48 parts of lanolin glycerine, 10 parts of surfactant, ethyl alcohol 5
Part, 9 parts of vitamin, 7 parts of essential oil and 4 parts of pearl powder, remaining is deionized water.
Citric acid, cosurfactant and emulsifier are further included in hand cleanser.
The surfactant is AESA.
The cosurfactant Cocoalkyl amido propyl betaine.
The vitamin is the mixing of vitamin B and vitamin E.
The extraction of essential oil raw material are the mixing of chamomile, honeysuckle and Chinese grooseberry.
One kind is washed one's hands liquid and preparation method thereof, is included the following steps：
A. after weighing lanolin glycerine, surfactant, cosurfactant, vitamin, pearl powder by metering respectively, put
In in container, deionized water then is being added in being stirred during emulsifier, and 28min is heated under the conditions of 60 DEG C, stands 50min,
It is spare；
B. ethyl alcohol and essential oil are added in gained mixture into step A, stirred to being uniformly mixed, it is spare；
C. citric acid is added in gained mixture into step B, and adjusts product pH value to faintly acid, packed to get end
Product.
The mixing speed is 380r/min.
The hand cleanser pH value is 4.5.
Embodiment 6
A kind of hand cleanser includes the raw material components of following mass fraction：47 parts of lanolin glycerine, 13 parts of surfactant, ethyl alcohol 9
Part, 6 parts of vitamin, 7 parts of essential oil and 4 parts of pearl powder, remaining is deionized water.
Citric acid, cosurfactant and emulsifier are further included in hand cleanser.
The surfactant is SAS.
The cosurfactant is the mixing in coconut monoethanol amide and glycol distearate.
The vitamin is vitamin C.
The extraction of essential oil raw material are aloe.
One kind is washed one's hands liquid and preparation method thereof, is included the following steps：
A. after weighing lanolin glycerine, surfactant, cosurfactant, vitamin, pearl powder by metering respectively, put
In in container, deionized water then is being added in being stirred during emulsifier, and 26min is heated under the conditions of 56 DEG C, stands 33min,
It is spare；
B. ethyl alcohol and essential oil are added in gained mixture into step A, stirred to being uniformly mixed, it is spare；
C. citric acid is added in gained mixture into step B, and adjusts product pH value to faintly acid, packed to get end
Product.
The mixing speed is 360 r/min.
The hand cleanser pH value is 4.8.
Embodiment 7
A kind of hand cleanser includes the raw material components of following mass fraction：49 parts of lanolin glycerine, 14 parts of surfactant, ethyl alcohol 9
Part, 6 parts of vitamin, 6 parts of essential oil and 4.5 parts of pearl powder, remaining is deionized water.
Citric acid, cosurfactant and emulsifier are further included in hand cleanser.
The surfactant is SAS.
The cosurfactant is the mixing of coconut monoethanol amide and glycol distearate.
The vitamin is the mixing of vitamin C and vitamin E.
The extraction of essential oil raw material include the mixing of lemon, chamomile and tea seed.
One kind is washed one's hands liquid and preparation method thereof, is included the following steps：
A. after weighing lanolin glycerine, surfactant, cosurfactant, vitamin, pearl powder by metering respectively, put
In in container, deionized water then is being added in being stirred during emulsifier, and 28min is heated under the conditions of 62 DEG C, stands 55min,
It is spare；
B. ethyl alcohol and essential oil are added in gained mixture into step A, stirred to being uniformly mixed, it is spare；
C. citric acid is added in gained mixture into step B, and adjusts product pH value to faintly acid, packed to get end
Product.
The mixing speed is 390 r/min.
The hand cleanser pH value is 5.5.
Claims (10)
1. a kind of hand cleanser, which is characterized in that include the raw material components of following mass fraction：45~50 parts of lanolin glycerine, table
3~5 parts of 8~15 parts of face activating agent, 5~10 parts of ethyl alcohol, 3~8 parts of vitamin, 5~8 parts of essential oil and pearl powder, remaining for go from
Sub- water.
2. hand cleanser according to claim 1, which is characterized in that include the raw material components of following mass fraction：Lanolin
4 parts of 48 parts of glycerine, 12 parts of surfactant, 7 parts of ethyl alcohol, 6 parts of vitamin, 7 parts of essential oil and pearl powder, remaining is deionized water.
3. hand cleanser according to claim 1, which is characterized in that citric acid, auxiliary surface are further included in the hand cleanser
Activating agent and emulsifier.
4. hand cleanser according to claim 1 or 2, which is characterized in that the surfactant includes AES, AESA, SAS
And one kind in AOS or arbitrary two or more mixing.
5. hand cleanser according to claim 3, which is characterized in that the cosurfactant includes Cocoalkyl amide
One kind or arbitrary two or more mixing in base propyl betaine, coconut monoethanol amide and glycol distearate.
6. hand cleanser according to claim 1 or 2, which is characterized in that the vitamin include vitamin B, vitamin C and
One kind or arbitrary two or more mixing in vitamin E.
7. hand cleanser according to claim 1 or 2, which is characterized in that the extraction of essential oil raw material include rose, lemon
A kind of or arbitrarily two or more mixing in lemon, aloe, chamomile, honeysuckle, Chinese grooseberry and tea seed.
8. the liquid and preparation method thereof of washing one's hands in a kind of 1-7 according to claim described in any one, which is characterized in that including walking as follows
Suddenly：
A. after weighing lanolin glycerine, surfactant, cosurfactant, vitamin, pearl powder by metering respectively, put
In in container, deionized water then is being added in being stirred during emulsifier, and 25~30min is heated under the conditions of 55~65 DEG C, it is quiet
30~60min is put, it is spare；
B. ethyl alcohol and essential oil are added in gained mixture into step A, stirred to being uniformly mixed, it is spare；
C. citric acid is added in gained mixture into step B, and adjusts product pH value to faintly acid, packed to get end
Product.
9. liquid and preparation method thereof according to claim 8 of washing one's hands, which is characterized in that the mixing speed is 350~400 r/
min。
10. liquid and preparation method thereof according to claim 8 of washing one's hands, which is characterized in that the hand cleanser pH value is 4.3-6.4.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711305307.2A CN108078889A (en) | 2017-12-11 | 2017-12-11 | A kind of hand cleanser and preparation method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711305307.2A CN108078889A (en) | 2017-12-11 | 2017-12-11 | A kind of hand cleanser and preparation method |
Publications (1)
| Publication Number | Publication Date |
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| CN108078889A true CN108078889A (en) | 2018-05-29 |
Family
ID=62174166
Family Applications (1)
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| CN201711305307.2A Pending CN108078889A (en) | 2017-12-11 | 2017-12-11 | A kind of hand cleanser and preparation method |
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111920708A (en) * | 2020-09-21 | 2020-11-13 | 青岛格林维尔环保技术有限公司 | Hand-washing-free disinfection gel and preparation method thereof |
| US10959933B1 (en) | 2020-06-01 | 2021-03-30 | The Procter & Gamble Company | Low pH skin care composition and methods of using the same |
| CN112972305A (en) * | 2019-12-13 | 2021-06-18 | 北京多宝德健康科技产业发展有限公司 | Healthy lotion of haw kernel distilled oil and its preparation technology |
| US11110049B2 (en) | 2017-06-23 | 2021-09-07 | The Procter & Gamble Company | Composition and method for improving the appearance of skin |
| US11583488B2 (en) | 2020-06-01 | 2023-02-21 | The Procter & Gamble Company | Method of improving penetration of a vitamin B3 compound into skin |
| US11622963B2 (en) | 2018-07-03 | 2023-04-11 | The Procter & Gamble Company | Method of treating a skin condition |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104644458A (en) * | 2014-06-10 | 2015-05-27 | 莫治玲 | Hand sanitizer |
-
2017
- 2017-12-11 CN CN201711305307.2A patent/CN108078889A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104644458A (en) * | 2014-06-10 | 2015-05-27 | 莫治玲 | Hand sanitizer |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11110049B2 (en) | 2017-06-23 | 2021-09-07 | The Procter & Gamble Company | Composition and method for improving the appearance of skin |
| US11622963B2 (en) | 2018-07-03 | 2023-04-11 | The Procter & Gamble Company | Method of treating a skin condition |
| CN112972305A (en) * | 2019-12-13 | 2021-06-18 | 北京多宝德健康科技产业发展有限公司 | Healthy lotion of haw kernel distilled oil and its preparation technology |
| US10959933B1 (en) | 2020-06-01 | 2021-03-30 | The Procter & Gamble Company | Low pH skin care composition and methods of using the same |
| US11583488B2 (en) | 2020-06-01 | 2023-02-21 | The Procter & Gamble Company | Method of improving penetration of a vitamin B3 compound into skin |
| US11911498B2 (en) | 2020-06-01 | 2024-02-27 | The Procter & Gamble Company | Low pH skin care composition and methods of using the same |
| CN111920708A (en) * | 2020-09-21 | 2020-11-13 | 青岛格林维尔环保技术有限公司 | Hand-washing-free disinfection gel and preparation method thereof |
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